ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2598 check: MH C KOG1772 Energy production and conversion Vacuolar H+-ATPase V1 sector, subunit G
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2598 913999 912080 -640
(640 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G 877 0.0
SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase 497 e-140
At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase 348 2e-95
YER073w [C] KOG2450 Aldehyde dehydrogenase 189 9e-48
Hs4507229 [C] KOG2451 Aldehyde dehydrogenase 187 4e-47
SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase 180 7e-45
YOR374w [C] KOG2450 Aldehyde dehydrogenase 175 2e-43
HsM4502031 [C] KOG2450 Aldehyde dehydrogenase 175 2e-43
Hs21361176 [C] KOG2450 Aldehyde dehydrogenase 175 2e-43
SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase 174 3e-43
CE07233 [C] KOG2450 Aldehyde dehydrogenase 174 4e-43
7301355 [C] KOG2451 Aldehyde dehydrogenase 174 4e-43
Hs4502047 [C] KOG2450 Aldehyde dehydrogenase 171 4e-42
7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 170 5e-42
SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase 170 7e-42
At1g79440 [C] KOG2451 Aldehyde dehydrogenase 168 3e-41
Hs10835045 [C] KOG2450 Aldehyde dehydrogenase 166 1e-40
At3g48170 [C] KOG2450 Aldehyde dehydrogenase 166 1e-40
Hs4502041 [C] KOG2450 Aldehyde dehydrogenase 165 2e-40
At2g24270 [C] KOG2450 Aldehyde dehydrogenase 164 3e-40
7297513 [C] KOG2450 Aldehyde dehydrogenase 164 4e-40
YPL061w [C] KOG2450 Aldehyde dehydrogenase 162 1e-39
YMR170c [C] KOG2450 Aldehyde dehydrogenase 160 6e-39
HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 159 9e-39
At3g48000 [C] KOG2450 Aldehyde dehydrogenase 159 2e-38
CE24573 [C] KOG2450 Aldehyde dehydrogenase 158 3e-38
Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 157 4e-38
At1g23800 [C] KOG2450 Aldehyde dehydrogenase 157 5e-38
Hs19923115 [C] KOG2450 Aldehyde dehydrogenase 156 8e-38
Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 156 8e-38
SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase 154 3e-37
Hs12007648 [C] KOG2450 Aldehyde dehydrogenase 152 2e-36
Hs11436533 [C] KOG2450 Aldehyde dehydrogenase 152 2e-36
CE23852 [C] KOG2450 Aldehyde dehydrogenase 152 2e-36
Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 151 3e-36
CE10542 [C] KOG2451 Aldehyde dehydrogenase 150 4e-36
YMR169c [C] KOG2450 Aldehyde dehydrogenase 150 7e-36
SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase 149 1e-35
CE29393 [C] KOG2450 Aldehyde dehydrogenase 149 1e-35
7301524 [C] KOG2450 Aldehyde dehydrogenase 149 1e-35
YBR006w [C] KOG2451 Aldehyde dehydrogenase 147 6e-35
CE13415 [C] KOG2456 Aldehyde dehydrogenase 145 1e-34
CE06980 [C] KOG2450 Aldehyde dehydrogenase 144 5e-34
CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 143 7e-34
Hs4502033 [C] KOG2450 Aldehyde dehydrogenase 142 2e-33
CE27441 [C] KOG2456 Aldehyde dehydrogenase 141 3e-33
At1g44170 [C] KOG2456 Aldehyde dehydrogenase 140 6e-33
At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase 139 1e-32
At1g74920 [C] KOG2450 Aldehyde dehydrogenase 139 1e-32
Hs4557303 [C] KOG2456 Aldehyde dehydrogenase 137 5e-32
Hs18603595 [C] KOG2456 Aldehyde dehydrogenase 137 5e-32
Hs21359829 [C] KOG2456 Aldehyde dehydrogenase 132 2e-30
HsM4502035 [C] KOG2456 Aldehyde dehydrogenase 131 4e-30
CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 127 7e-29
Hs4502043 [C] KOG2456 Aldehyde dehydrogenase 125 2e-28
Hs4557343 [C] KOG2453 Aldehyde dehydrogenase 120 8e-27
7304212 [C] KOG2456 Aldehyde dehydrogenase 116 1e-25
CE01232 [C] KOG2453 Aldehyde dehydrogenase 113 1e-24
7293810 [C] KOG2453 Aldehyde dehydrogenase 111 4e-24
Hs4502045 [C] KOG2456 Aldehyde dehydrogenase 110 5e-24
At4g36250 [C] KOG2456 Aldehyde dehydrogenase 107 6e-23
At1g54100 [C] KOG2453 Aldehyde dehydrogenase 106 9e-23
7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase 105 3e-22
SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrog... 96 2e-19
CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 90 1e-17
YMR110c [C] KOG2456 Aldehyde dehydrogenase 88 3e-17
Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 88 5e-17
7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 87 6e-17
Hs20481620 [C] KOG2456 Aldehyde dehydrogenase 84 9e-16
YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 79 3e-14
At4g34240 [C] KOG2456 Aldehyde dehydrogenase 67 6e-11
Hs20546780 [C] KOG2450 Aldehyde dehydrogenase 62 4e-09
7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase 54 1e-06
>YHR039c [C] KOG1772 Vacuolar H+-ATPase V1 sector subunit G
Length = 644
Score = 877 bits (2266), Expect = 0.0
Identities = 428/643 (66%), Positives = 517/643 (79%), Gaps = 8/643 (1%)
Query: 6 TQVYLNSSVLQQLNATIQAYLTDLVSTGQTFNSSQ--IVSENVRFTS-GTLVVGLISIYF 62
++VYLNS ++ LN+T+QAY + SQ I+ +N + TLV + ++Y
Sbjct: 2 SKVYLNSDMINHLNSTVQAYFNLWLEKQNAIMRSQPQIIQDNQKLIGITTLVASIFTLYV 61
Query: 63 IYQWVFSKSKLPSA---VQFKLYIPDAAHKHWKGKRMFPCSVYNPEQPHMIQSYCPATGQ 119
+ + + + +K S+ V+F L P+AA +WKGKR +++NPE+P+ IQ +CPATGQ
Sbjct: 62 LVKIISTPAKCSSSYKPVKFSLPAPEAAQNNWKGKRSVSTNIWNPEEPNFIQCHCPATGQ 121
Query: 120 FLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRD 179
+LGSF S ++ DIDE+V A +AQ W + RL+VL SL ++IL NQ+ IARVACRD
Sbjct: 122 YLGSFPSKTEADIDEMVSKAGKAQSTWGNSDFSRRLRVLASLHDYILNNQDLIARVACRD 181
Query: 180 SGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVV 239
SGKTMLDASMGEILVTLEKIQW I+HG+ L+PS RPGPTNFFMKWYKGAE+RYEPLGV+
Sbjct: 182 SGKTMLDASMGEILVTLEKIQWTIKHGQRALQPSRRPGPTNFFMKWYKGAEIRYEPLGVI 241
Query: 240 GAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLV 299
+IVSWNYPFHNLLGPI+A++FTGNA+VVKCSEQVVWSS+FF L+++ L+AC DP+LV
Sbjct: 242 SSIVSWNYPFHNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKCLEACDEDPDLV 301
Query: 300 QLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAF 359
QLCYCLPPT NDD+ANYFTSHP FKH+TFIGS+PVAH++LK AA SLTPVVVELGGKDAF
Sbjct: 302 QLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTPVVVELGGKDAF 361
Query: 360 IVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRV--GQLRLG 417
IVLDS K+L ALSSIIMRGTFQS+GQNCIGIERVIVS +NYD LV ILNDR+ LR G
Sbjct: 362 IVLDSAKNLDALSSIIMRGTFQSSGQNCIGIERVIVSKENYDDLVKILNDRMTANPLRQG 421
Query: 418 SDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLL 477
SDID+LE+VDMGAMISDNRF +LE L+ DA++KGA+LL GGSR+ HP YPQGH+FQPTLL
Sbjct: 422 SDIDHLENVDMGAMISDNRFDELEALVKDAVAKGARLLQGGSRFKHPKYPQGHYFQPTLL 481
Query: 478 VDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSL 537
VDVT +M+I+ NEVFGPIL +M+AK+TD C++LAN+APFGLGGS+FGAD ECN VANSL
Sbjct: 482 VDVTPEMKIAQNEVFGPILVMMKAKNTDHCVQLANSAPFGLGGSVFGADIKECNYVANSL 541
Query: 538 TTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVCFDTLPFISTQIPK 597
TGNVAINDFATFYVCQLPFGG+N CNAKSVCFDTLPF+STQIPK
Sbjct: 542 QTGNVAINDFATFYVCQLPFGGINGSGYGKFGGEEGLLGLCNAKSVCFDTLPFVSTQIPK 601
Query: 598 PLDYPIKSNSKAWEFVKAFITGAYAVSTWQRIKSLVSLAKNAN 640
PLDYPI++N+KAW FVK+FI GAY STWQRIKSL SLAK A+
Sbjct: 602 PLDYPIRNNAKAWNFVKSFIVGAYTNSTWQRIKSLFSLAKEAS 644
>SPBC21C3.15c [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 522
Score = 497 bits (1279), Expect = e-140
Identities = 246/509 (48%), Positives = 332/509 (64%), Gaps = 11/509 (2%)
Query: 113 YCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAI 172
YCP G LG K + +DID+ ++LAE AQ +W TS ER L +LK I+ NQ+
Sbjct: 8 YCPGDGSLLGEVKLFNKSDIDQSIILAEEAQKEWKSTSFAERRNFLKALKENIIRNQDKY 67
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVR 232
A +AC+D+GKT++DA+ GEILVTLEKI W + +GE L+P+ RP N + YKG V+
Sbjct: 68 AEIACKDTGKTLVDAAFGEILVTLEKINWTLANGEQSLRPTKRP---NSLLTSYKGGYVK 124
Query: 233 YEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKAC 292
YEPLGV+ A+VSWNYP HN LGPI++++F GNA+VVK SE WS+ + +V+ L++
Sbjct: 125 YEPLGVIAALVSWNYPLHNALGPIISALFAGNAIVVKGSELTAWSTHQYCEMVRSLLQSM 184
Query: 293 GHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVE 352
GH P LVQ CLP D A++ TSH KH+TFIGS+P+A V +AA LTP+ +E
Sbjct: 185 GHSPELVQCITCLP-----DVADHLTSHSGIKHITFIGSQPIAKLVAASAAKQLTPLCLE 239
Query: 353 LGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVG 412
LGGKD I+ D + L+ + SI+MRG FQSAGQNCIGIER+I YD +++ L +R+
Sbjct: 240 LGGKDPCILTDDHR-LEEILSIVMRGVFQSAGQNCIGIERIIALDGVYDTIITKLYNRIS 298
Query: 413 QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFF 472
+RLG N DVDMGAM+S+NRF LE+LI DA+SKGA+L++GG R+ HP YP+G++F
Sbjct: 299 TMRLGMYTQN--DVDMGAMVSNNRFDHLESLIQDAVSKGARLVYGGHRFQHPKYPKGNYF 356
Query: 473 QPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNR 532
PTLLVD T +M+I+ E F PI V RAK + + +AN FGLG S+FG D C
Sbjct: 357 LPTLLVDATNEMKIAQEECFAPIALVFRAKSPEHALEIANGTEFGLGASVFGRDKQLCQY 416
Query: 533 VANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVCFDTLPFIS 592
++L TG VA+NDF FY+ Q+PFGG CN+K++ +D I
Sbjct: 417 FTDNLETGMVAVNDFGAFYLLQMPFGGCKKSGYGRFAGYEGLRGICNSKAIAYDRFSAIH 476
Query: 593 TQIPKPLDYPIKSNSKAWEFVKAFITGAY 621
T IP +DYPI + KAW+FV+ + Y
Sbjct: 477 TGIPPAVDYPIPDSQKAWQFVRGLMGTVY 505
>At3g66658 [C] KOG2454 Betaine aldehyde dehydrogenase
Length = 578
Score = 348 bits (892), Expect = 2e-95
Identities = 195/529 (36%), Positives = 297/529 (55%), Gaps = 33/529 (6%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQ 169
+Q Y PAT ++LG F ++S T+++E V L+ +AQ WA++S K R Q L L +I+E+Q
Sbjct: 66 VQCYEPATMKYLGYFPALSPTEVEERVTLSRKAQKTWAQSSFKLRRQFLRILLKYIIEHQ 125
Query: 170 EAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGA 229
E I V+ RD+GKTM+DAS+GEI+ T EKI W++ GE LKP +R +K +
Sbjct: 126 ELICEVSSRDTGKTMVDASLGEIMTTCEKITWLLSEGERWLKPESRSSGRAML---HKVS 182
Query: 230 EVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEAL 289
V + PLGV+GAIV WNYPFHN+ P++A++F+GN +V+K SE WS F+ ++Q AL
Sbjct: 183 RVEFHPLGVIGAIVPWNYPFHNIFNPMLAAVFSGNGIVIKVSEHASWSGCFYFRIIQAAL 242
Query: 290 KACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPV 349
A G NLV + TG ++ + F+GS V +++ AA++LTPV
Sbjct: 243 AAVGAPENLVDVITGFAETGEALVSS-------VDKMIFVGSTAVGKMIMRNAAETLTPV 295
Query: 350 VVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILND 409
+ELGGKDAFI+ + D+ ++ + +RGT QS+GQNC G ER V Y A + +
Sbjct: 296 TLELGGKDAFIICEDA-DVSHVAQVAVRGTLQSSGQNCAGAERFYVHKDIYTAFIGQVTK 354
Query: 410 RVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQG 469
V + G + DMGA+ L++L++DAL KGA++ GS +
Sbjct: 355 IVKSVSAGPPLTG--RYDMGAICLQEHSEHLQSLVNDALDKGAEIAVRGSFGHLGEDAVD 412
Query: 470 HFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGE 529
+F PT+L++V +M+I E FGPI+ +M+ ++ I+LAN + + LG ++F
Sbjct: 413 QYFPPTVLINVNHNMKIMKEEAFGPIMPIMQFSTDEEVIKLANDSRYALGCAVFSGSKHR 472
Query: 530 CNRVANSLTTGNVAINDFATFYVCQ-LPFGGLNXXXXXXXXXXXXXXXXCNAKSVCFDTL 588
++A+ + G AINDFA+ Y+CQ LPFGG+ C KSV
Sbjct: 473 AKQIASQIQCGVAAINDFASNYMCQSLPFGGVKDSGFGRFAGIEGLRACCLVKSV----- 527
Query: 589 PFISTQIPKPLDYPIKSNSKAWEFVKAFITGAYAVSTWQRIKSLVSLAK 637
YP+ N A+EF +A + Y ++ W R++SL+ + K
Sbjct: 528 ------------YPVAEN--AFEFQEALVETLYGLNIWDRLRSLIDVLK 562
>YER073w [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 189 bits (481), Expect = 9e-48
Identities = 134/437 (30%), Positives = 220/437 (49%), Gaps = 26/437 (5%)
Query: 124 FKSMSDTDIDEIVLLAERA-QLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGK 182
+K+M D D+DE V A++A + +W+ + R + L +L + + ++QE +A + D+GK
Sbjct: 76 YKAMED-DVDEAVAAAKKAFETKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGK 134
Query: 183 TMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAI 242
++ A G++ + + ++ + + G +F EPLGV G I
Sbjct: 135 SLFCAR-GDVALVSKYLRSCGGWADKIYGNVIDTGKNHFTYSIK-------EPLGVCGQI 186
Query: 243 VSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLC 302
+ WN+P I ++ TGN VV+K +E S+ F + L QEA G +V +
Sbjct: 187 IPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEA----GIPAGVVNI- 241
Query: 303 YCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVL 362
LP +G ++HP K + F GS H++K AAD++ V +ELGGK IV
Sbjct: 242 --LPGSGRV-VGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVF 298
Query: 363 DSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDN 422
DL I G F ++G+ C R+ + Y+ ++ L D L++G D
Sbjct: 299 ADA-DLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFD- 356
Query: 423 LEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTE 482
E+V GA SD + ++ + + A S+GA+L+ GG+R+ +G+F +PT+ DV
Sbjct: 357 -EEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGS----KGYFVKPTVFADVKG 411
Query: 483 DMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNV 542
DM+I EVFGPI+TV + D+ I +AN + +GL I D + V+ + G V
Sbjct: 412 DMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTV 471
Query: 543 AINDFATFYVCQLPFGG 559
IN + F+ +PFGG
Sbjct: 472 WINTYNNFHQ-NVPFGG 487
>Hs4507229 [C] KOG2451 Aldehyde dehydrogenase
Length = 535
Score = 187 bits (475), Expect = 4e-47
Identities = 142/501 (28%), Positives = 230/501 (45%), Gaps = 36/501 (7%)
Query: 93 GKRMFPCSVYNPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLK 152
G R P + P Q PA+G LG + V A A +W + S K
Sbjct: 66 GGRWLPAAATFPVQD-------PASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAK 118
Query: 153 ERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGE----D 208
ER +L N +++N++ +AR+ +SGK + +A GEIL + ++W E D
Sbjct: 119 ERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAH-GEILYSAFFLEWFSEEARRVYGD 177
Query: 209 VLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVV 268
++ A+ + A V +P+GV I WN+P + + A++ G VVV
Sbjct: 178 IIHTPAKD----------RRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVV 227
Query: 269 KCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTF 328
K +E +S+ L + E G + + C + + P+ ++F
Sbjct: 228 KPAEDTPFSA----LALAELASQAGIPSGVYNVIPCSRKNAKE-VGEAICTDPLVSKISF 282
Query: 329 IGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCI 388
GS +L AA+S+ V +ELGG FIV DS QA++ M F++ GQ C+
Sbjct: 283 TGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGA-MASKFRNTGQTCV 341
Query: 389 GIERVIVSAKNYDALVSILNDRVGQ-LRLGSDIDNLEDVDMGAMISDNRFGQLENLISDA 447
+ +V +DA V + + + LR+G+ + E G +I++ ++E ++DA
Sbjct: 342 CSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFE--EGTTQGPLINEKAVEKVEKQVNDA 399
Query: 448 LSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDC 507
+SKGA ++ GG R+ +FF+PTLL +VT+DM +H E FGP+ V++ ++
Sbjct: 400 VSKGATVVTGGKRHQLGK----NFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEA 455
Query: 508 IRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXX 567
I +ANAA GL G + D + RVA L G V +N+ V + PFGG+
Sbjct: 456 IAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSV-ECPFGGVKQSGLGR 514
Query: 568 XXXXXXXXXXCNAKSVCFDTL 588
K VC+ L
Sbjct: 515 EGSKYGIDEYLELKYVCYGGL 535
>SPAC9E9.09c [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 180 bits (456), Expect = 7e-45
Identities = 132/454 (29%), Positives = 220/454 (48%), Gaps = 28/454 (6%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLLSLKNFIL 166
++ Y P+T + + + D+D V +A A W K S +R + L L + I
Sbjct: 40 VKVYSPSTEKLICEVADADEEDVDIAVKVARAAFQTDAPWRKFSSAQRGRCLSRLADCIE 99
Query: 167 ENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWY 226
+N E +A + D+GK+ + + G++ + ++ +G K + T+
Sbjct: 100 QNLEYLASIETLDNGKS-ITLARGDVQAAADCFRY---YGGWADKDYGQTIETDI----K 151
Query: 227 KGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQ 286
+ A R+EP+GV G I+ WN+PF I ++ GN +++K +E S+ T V
Sbjct: 152 RFAYTRHEPIGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLSALCLTKFVP 211
Query: 287 EALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS- 345
E CG P ++ + L G N +SH + F GS V V++AAA S
Sbjct: 212 E----CGFPPGVINV---LSGDGRR-CGNAISSHMDIDKVAFTGSTGVGRMVMRAAASSN 263
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
L V +ELGGK IV + DL + + G F ++GQ C RV V YD +
Sbjct: 264 LKKVTLELGGKSPNIVFNDA-DLDSAAVWTNYGIFYNSGQVCCAGSRVYVQEDVYDEFIK 322
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
+ + L++G ED GA +S ++ ++ + I ++ GAKL GG R+ +
Sbjct: 323 RMVAKAKTLKVGDPF--AEDTFQGAQVSKQQYERIVSYIESGIAHGAKLEIGGKRHGN-- 378
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGA 525
G+F +PT+L +VTEDM + E+FGP+L V++ K ++ IR N + +GL +
Sbjct: 379 --LGYFVEPTILSNVTEDMAVGKEEIFGPVLAVIKFKTIEEAIRRGNNSTYGLAAGVHTN 436
Query: 526 DFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
+ +V+N+L G V +N + + Q+PFGG
Sbjct: 437 NITNAIKVSNALEAGTVWVNCYNLLH-HQIPFGG 469
>YOR374w [C] KOG2450 Aldehyde dehydrogenase
Length = 519
Score = 175 bits (444), Expect = 2e-43
Identities = 123/449 (27%), Positives = 211/449 (46%), Gaps = 26/449 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P+T + + + D++E V A+RA W +R + L L I ++++ I
Sbjct: 67 PSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVI 126
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVR 232
A + D+GK + +S G++ + + ++ + + G T+F + +
Sbjct: 127 ASIETLDNGKA-ISSSRGDVDLVINYLKSSAGFADKIDGRMIDTGRTHF-------SYTK 178
Query: 233 YEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKAC 292
+PLGV G I+ WN+P I ++ TGN VV+K +E S+ L V + +
Sbjct: 179 RQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAE----STPLSALYVSKYIPQA 234
Query: 293 GHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVE 352
G P ++ + T+HP K + F GS H+ ++AA L V +E
Sbjct: 235 GIPPGVINIVSGFGKI----VGEAITNHPKIKKVAFTGSTATGRHIYQSAAAGLKKVTLE 290
Query: 353 LGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVG 412
LGGK IV + +A+ +II+ G + ++G+ C RV V YD +
Sbjct: 291 LGGKSPNIVFADAELKKAVQNIIL-GIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASE 349
Query: 413 QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFF 472
+++G D E GA S + ++ + ++GA L+ GG R +G+F
Sbjct: 350 SIKVGDPFD--ESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGS----KGYFI 403
Query: 473 QPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNR 532
+PT+ DV EDM+I E+FGP++TV + K D+ I +AN + +GL I ++ +
Sbjct: 404 KPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALK 463
Query: 533 VANSLTTGNVAINDFATFYVCQLPFGGLN 561
VA+ + G V IN + F+ +PFGG N
Sbjct: 464 VADRVNAGTVWINTYNDFHHA-VPFGGFN 491
>HsM4502031 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 175 bits (443), Expect = 2e-43
Identities = 141/484 (29%), Positives = 224/484 (46%), Gaps = 41/484 (8%)
Query: 80 KLYIPDAAHKHWKGKRMFPCSVYNPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLA 139
K++I + H GK+ FP V+NP AT + L + D+D+ V A
Sbjct: 22 KIFINNEWHDSVSGKK-FP--VFNP-----------ATEEELCQVEEGDKEDVDKAVKAA 67
Query: 140 ERA---QLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTL 196
+A W ER ++L L + I ++ +A + + GK +A + ++ +
Sbjct: 68 RQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCI 127
Query: 197 EKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPI 256
+ +++ D ++ P NFF R+EP+GV G I+ WN+P L+ I
Sbjct: 128 KTLRYCAGWA-DKIQGRTIPIDGNFF------TYTRHEPIGVCGQIIPWNFPLVMLIWKI 180
Query: 257 VASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANY 316
++ GN VVVK +EQ ++ L++EA G P +V + PT A
Sbjct: 181 GPALSCGNTVVVKPAEQTPLTALHVASLIKEA----GFPPGVVNIVPGYGPT----AGAA 232
Query: 317 FTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVVVELGGKDAFIVLDSVKDLQALSSII 375
+SH + F GS V + +AA S L V +ELGGK IVL DL
Sbjct: 233 ISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADA-DLDNAVEFA 291
Query: 376 MRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDN 435
G F GQ CI R+ V YD V +R + LG+ + V G I
Sbjct: 292 HHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLT--PGVTQGPQIDKE 349
Query: 436 RFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPI 495
++ ++ +LI +GAKL GG + + +G+F QPT+ +VT++M+I+ E+FGP+
Sbjct: 350 QYDKILDLIESGKKEGAKLECGGGPWGN----KGYFVQPTVFSNVTDEMRIAKEEIFGPV 405
Query: 496 LTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQL 555
+M+ K DD I+ AN +GL +F D + ++++L G V +N + Q
Sbjct: 406 QQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGV-VSAQC 464
Query: 556 PFGG 559
PFGG
Sbjct: 465 PFGG 468
>Hs21361176 [C] KOG2450 Aldehyde dehydrogenase
Length = 501
Score = 175 bits (443), Expect = 2e-43
Identities = 141/484 (29%), Positives = 224/484 (46%), Gaps = 41/484 (8%)
Query: 80 KLYIPDAAHKHWKGKRMFPCSVYNPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLA 139
K++I + H GK+ FP V+NP AT + L + D+D+ V A
Sbjct: 22 KIFINNEWHDSVSGKK-FP--VFNP-----------ATEEELCQVEEGDKEDVDKAVKAA 67
Query: 140 ERA---QLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTL 196
+A W ER ++L L + I ++ +A + + GK +A + ++ +
Sbjct: 68 RQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCI 127
Query: 197 EKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPI 256
+ +++ D ++ P NFF R+EP+GV G I+ WN+P L+ I
Sbjct: 128 KTLRYCAGWA-DKIQGRTIPIDGNFF------TYTRHEPIGVCGQIIPWNFPLVMLIWKI 180
Query: 257 VASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANY 316
++ GN VVVK +EQ ++ L++EA G P +V + PT A
Sbjct: 181 GPALSCGNTVVVKPAEQTPLTALHVASLIKEA----GFPPGVVNIVPGYGPT----AGAA 232
Query: 317 FTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVVVELGGKDAFIVLDSVKDLQALSSII 375
+SH + F GS V + +AA S L V +ELGGK IVL DL
Sbjct: 233 ISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADA-DLDNAVEFA 291
Query: 376 MRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDN 435
G F GQ CI R+ V YD V +R + LG+ + V G I
Sbjct: 292 HHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLT--PGVTQGPQIDKE 349
Query: 436 RFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPI 495
++ ++ +LI +GAKL GG + + +G+F QPT+ +VT++M+I+ E+FGP+
Sbjct: 350 QYDKILDLIESGKKEGAKLECGGGPWGN----KGYFVQPTVFSNVTDEMRIAKEEIFGPV 405
Query: 496 LTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQL 555
+M+ K DD I+ AN +GL +F D + ++++L G V +N + Q
Sbjct: 406 QQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGV-VSAQC 464
Query: 556 PFGG 559
PFGG
Sbjct: 465 PFGG 468
>SPAC922.07c [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 174 bits (442), Expect = 3e-43
Identities = 121/447 (27%), Positives = 202/447 (45%), Gaps = 23/447 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
P+ + + + +ID V A+ A W K E+ ++L+ L ++ + +A
Sbjct: 41 PSIEEVIAKVYLAGEKEIDYAVKSAKEAFKTWKKVPGSEKGELLMKLAELTEKHADTLAA 100
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYE 234
+ DSGK ++ + G++ T+ +++ + + GP K A +
Sbjct: 101 IEAMDSGKPLVSNARGDVDGTIALLRYCAGWADKIYGQVIPTGPE-------KLAYAKRT 153
Query: 235 PLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGH 294
P+GV G IV WNYP + I ++ GN +++K +E S +F LV+EA G
Sbjct: 154 PIGVCGQIVPWNYPLNMAGWKIAPALAAGNCIIIKSAETTPLSLLYFATLVEEA----GF 209
Query: 295 DPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELG 354
+V + L A +Y HP + F GS V V + AA +L V +E G
Sbjct: 210 PKGVVNIISGLGTV----AGSYMAKHPGIDKIAFTGSTKVGVIVQQLAASNLKAVTLECG 265
Query: 355 GKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQ- 413
GK F+V + DL G ++GQ C R+ V YD + + V Q
Sbjct: 266 GKSPFLVFEDA-DLDQAVKWAALGIMYNSGQICTSNSRIYVQDSVYDKFIELFKKHVIQD 324
Query: 414 LRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQ 473
+G D ++ +G +++ ++ +++N I +GAKL+ G QG+F
Sbjct: 325 YIVGMPFD--DNTVVGPVVNKTQYNRIKNYIEQGKKEGAKLVLGDEPLP---LKQGYFIS 379
Query: 474 PTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRV 533
PT+ D +E+M I E+FGP++ + + K D+ I AN +GL F D +RV
Sbjct: 380 PTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIEKANNTTYGLAAMCFTKDLERAHRV 439
Query: 534 ANSLTTGNVAINDFATFYVCQLPFGGL 560
++ L G V IN + Q PFGG+
Sbjct: 440 SDELEAGMVFINSTENSDI-QAPFGGI 465
>CE07233 [C] KOG2450 Aldehyde dehydrogenase
Length = 687
Score = 174 bits (441), Expect = 4e-43
Identities = 129/474 (27%), Positives = 209/474 (43%), Gaps = 22/474 (4%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
P +G+ + ++ + +D V A++AQ QWAK+S ER ++L + + + IA
Sbjct: 228 PRSGKPMATWHYATRDQVDLTVKEAKKAQKQWAKSSWMERSEILKKTGDLLKTHCNDIAY 287
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYE 234
C +GK + +A ++L ++ + D+L + + A R
Sbjct: 288 WECISNGKPIAEAK-ADVLSCVDTFYFYSGIASDLLGQHVPLDASRY-------AYTRRL 339
Query: 235 PLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGH 294
P+GVV AI +WNYP ++ GNAV+ K S S L++ E LK+ G
Sbjct: 340 PVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSPL----SPVTALILAEILKSAGL 395
Query: 295 DPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAAD-SLTPVVVEL 353
+ + G+ + A H ++F GS P ++KA AD ++ PV +EL
Sbjct: 396 PDGVFNVIQ-----GDAETAQDLIHHDGVSKVSFTGSIPTGKKIMKACADRNIKPVTLEL 450
Query: 354 GGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQ 413
GGK A IV D D+ + S M F S GQ C +V+V L D +
Sbjct: 451 GGKSALIVFDDA-DIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVLKEFTKKLVDHTQK 509
Query: 414 LRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQ 473
+++G + ED +G+ IS ++E IS A+++GA L GG R G +
Sbjct: 510 MKIGDPLK--EDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVAVHGLENGFYLS 567
Query: 474 PTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRV 533
P +L +T M + E+FG +L ++ D+ I++AN GL + D RV
Sbjct: 568 PCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGLVTKDLSRSYRV 627
Query: 534 ANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVCFDT 587
+ L GNV +N + +PFGG+ + KSV +T
Sbjct: 628 SEQLNAGNVYVNTYNDVSPL-VPFGGVGESGFGRENGTAVLEHYTHLKSVFVNT 680
>7301355 [C] KOG2451 Aldehyde dehydrogenase
Length = 509
Score = 174 bits (441), Expect = 4e-43
Identities = 129/484 (26%), Positives = 216/484 (43%), Gaps = 35/484 (7%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
PA G +G +M+ D + + A++A +W + K+R +L I ++ + I
Sbjct: 52 PANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLKKWHKLIEQHSQEI 111
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDV---LKPSARPGPTNFFMKWYKGA 229
A + +SGK ++ S GE+ ++W E + + PSA P MK
Sbjct: 112 AEIMTAESGKP-INESKGEVAYGNAFVEWFAEEARRIYGEIVPSASPNREIIVMK----- 165
Query: 230 EVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEAL 289
+P+GV I WN+P + A++ G VVVK SE ++ L +A
Sbjct: 166 ----QPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDA- 220
Query: 290 KACGHDPNLVQLCYCLPPTGNDDA--ANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLT 347
G ++ + T N A + F P + ++F GS V + + +AD +
Sbjct: 221 ---GIPKGVINVV-----TTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIK 272
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
+ +ELGG FIV DS D++ M F++ GQ C+ R V YD V L
Sbjct: 273 RICLELGGNAPFIVFDSA-DIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQL 331
Query: 408 NDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYP 467
RV L++G DV +G +I++ +F ++ + DA SK A ++ GG P
Sbjct: 332 KKRVEALKIGDGQGC--DVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQ----PLPD 385
Query: 468 QGH-FFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGAD 526
+G F+ PT++ DV Q+ EVFGP+++++R +D ++ ++ AN GL G + +
Sbjct: 386 KGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSEN 445
Query: 527 FGECNRVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVCFD 586
+ RVA L G V +N+ + PFGG+ + K +C
Sbjct: 446 LQQVFRVAKRLEVGMVGVNE-GIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYICMG 504
Query: 587 TLPF 590
L +
Sbjct: 505 NLKY 508
>Hs4502047 [C] KOG2450 Aldehyde dehydrogenase
Length = 493
Score = 171 bits (432), Expect = 4e-42
Identities = 127/483 (26%), Positives = 215/483 (44%), Gaps = 33/483 (6%)
Query: 111 QSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQE 170
+++ PATG+ + +F + +++ V A+ A W++ S ER ++LL I E ++
Sbjct: 29 KAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAARIIRERED 88
Query: 171 AIARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKW 225
IA + C ++GK++ +A + +I ++ + +++ GE + P G T
Sbjct: 89 EIATMECINNGKSIFEARL-DIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYT------ 141
Query: 226 YKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLV 285
R EPLGV I +WNYPF ++ GNA+V K S S+ LL+
Sbjct: 142 ------RREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSA----LLL 191
Query: 286 QEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS 345
E G P L + TG + HP ++F GS P +++ +A
Sbjct: 192 AEIYSEAGVPPGLFNVVQGGAATGQ-----FLCQHPDVAKVSFTGSVPTGMKIMEMSAKG 246
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
+ PV +ELGGK I+ A+ +M F + GQ C RV V + D
Sbjct: 247 IKPVTLELGGKSPLIIFSDCDMNNAVKGALM-ANFLTQGQVCCNGTRVFVQKEILDKFTE 305
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRY--NH 463
+ + ++++G + LED MG +I+ ++ + A +GAK+L GG Y
Sbjct: 306 EVVKQTQRIKIGDPL--LEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPED 363
Query: 464 PNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIF 523
P G++ +P +L + +DM E+FGP+++++ + + AN FGL +F
Sbjct: 364 PKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVF 423
Query: 524 GADFGECNRVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSV 583
D +RV L G IN++ V +LPFGG K+V
Sbjct: 424 TRDIQRAHRVVAELQAGTCFINNYNVSPV-ELPFGGYKKSGFGRENGRVTIEYYSQLKTV 482
Query: 584 CFD 586
C +
Sbjct: 483 CVE 485
>7290043 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 552
Score = 170 bits (431), Expect = 5e-42
Identities = 118/436 (27%), Positives = 208/436 (47%), Gaps = 20/436 (4%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQ 169
I + PAT Q + + ++ + ++A W+ S+ R QV+ L+ I EN
Sbjct: 75 IDVHDPATNQVVTRVPKATQAEMQAALESNKKAFRSWSNQSILTRQQVMFKLQALIKENM 134
Query: 170 EAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGA 229
+A+ ++ GKT+ DA G++L L+ ++EH + PS + G T +
Sbjct: 135 GELAKNITKEQGKTLADAE-GDVLRGLQ----VVEHCCSI--PSLQMGETVANVARDMDT 187
Query: 230 EVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEAL 289
PLGV + +N+P L +I TGN +++K SE+V + T+L+ E L
Sbjct: 188 YSLVLPLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGA----TMLLMELL 243
Query: 290 KACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPV 349
G P +V + + G DA N+ P K ++F+GS ++ + A + V
Sbjct: 244 NEAGCPPGVVNVIH-----GQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRV 298
Query: 350 VVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILND 409
+G K+ I+L L+ + F +AGQ C+ + + + A + L +
Sbjct: 299 QSNMGAKNHGIILGDANKENTLNQLA-GAAFGAAGQRCMALSTAVFVG-DAQAWIPDLVE 356
Query: 410 RVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQG 469
R +L++ + ++ D+G +IS ++ +LI + +GAKL+ G + P Y G
Sbjct: 357 RAQKLKVNAG--HVPGTDVGPVISAASRQRINDLIESGVKEGAKLILDGRKITVPGYEDG 414
Query: 470 HFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGE 529
+F PT+L DVT M+ E+FGP+L +++A DD I + NA P+G G ++F +
Sbjct: 415 YFVGPTILSDVTPSMKCYTEEIFGPVLVILKADTLDDAIGIVNANPYGNGTAVFTTNGAA 474
Query: 530 CNRVANSLTTGNVAIN 545
+ N + G V +N
Sbjct: 475 ARKFVNEIDAGQVGVN 490
>SPAC1002.12c [C] KOG2451 Aldehyde dehydrogenase
Length = 498
Score = 170 bits (430), Expect = 7e-42
Identities = 122/477 (25%), Positives = 220/477 (45%), Gaps = 27/477 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
P + L MS + + + +A A L + + +KER +L + I+EN + +A
Sbjct: 46 PGLNETLAPVTDMSVEETRKAIKVAHEAFLSYRNSDIKERYAILRRWYDLIMENADDLAT 105
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPG-PTNFFMKWYKGAEVRY 233
+ ++GK + DA GE++ + I W + S+ P N +
Sbjct: 106 MMTLENGKALGDAK-GEVVYAAKFIDWFAGEALRISGDSSMSSNPQNRII-------TIK 157
Query: 234 EPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACG 293
+P+GVVG I WN+P + + A++ G VV++ + + + F L + + + G
Sbjct: 158 QPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAE----TPFTALALAKLAERAG 213
Query: 294 HDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVEL 353
++ + P+ + T++P+ + ++F GS V + K ++ +L + +EL
Sbjct: 214 VPAGVLNMVTANSPS---EHGIELTTNPLIRKVSFTGSTNVGKILAKQSSSTLKKLSLEL 270
Query: 354 GGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQ 413
GG FIV + DL+ + +M F+ +GQ C+ R+ V + YDA V ++ +RV +
Sbjct: 271 GGNAPFIVFEDA-DLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFVDLVTERVSK 329
Query: 414 LRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNH--PNYPQGHF 471
+LG +D V G +IS+ +++ + DA+ KG ++ GG ++ P Y
Sbjct: 330 FKLGYGLD--AGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLGPMY----- 382
Query: 472 FQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECN 531
F+PT++++ + M IS E FGP+ + + D+ + AN +P GL G +F D
Sbjct: 383 FEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDISRVF 442
Query: 532 RVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVCFDTL 588
RV +L G V N V PFGG+ + KS+ TL
Sbjct: 443 RVGEALQVGMVGCNTGLVSDVLS-PFGGVKESGFGREGSKYGISEYLDIKSLTISTL 498
>At1g79440 [C] KOG2451 Aldehyde dehydrogenase
Length = 528
Score = 168 bits (425), Expect = 3e-41
Identities = 123/447 (27%), Positives = 213/447 (47%), Gaps = 25/447 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
PATG+ + M + ++ + + A W++ + ER +VL + ++ ++E + +
Sbjct: 75 PATGEIIADVACMGTKETNDAIASSYEAFTSWSRLTAGERSKVLRRWYDLLIAHKEELGQ 134
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYE 234
+ + GK + +A +GE+ I++ E + V P ++ + V +
Sbjct: 135 LITLEQGKPLKEA-IGEVAYGASFIEYYAEEAKRVYGDIIPPNLSD------RRLLVLKQ 187
Query: 235 PLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGH 294
P+GVVGAI WN+P + + ++ +G VVVK SE ++ L E G
Sbjct: 188 PVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTA----LAAAELALQAGV 243
Query: 295 DPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELG 354
P + + P + + + P + +TF GS V ++ AAA ++ V +ELG
Sbjct: 244 PPGALNVVMGNAP----EIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKVSLELG 299
Query: 355 GKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQL 414
G IV D DL + F+++GQ C+ RV+V YD ++ V +L
Sbjct: 300 GNAPSIVFDDA-DLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEAVQKL 358
Query: 415 RLGSDIDNLED-VDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQ 473
+G D D G +I+D ++E + DA+SKGAK++ GG R++ F++
Sbjct: 359 EVG---DGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMT----FYE 411
Query: 474 PTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRV 533
PT++ DV+++M +S E+FGP+ ++R K +D IR+AN GL IF RV
Sbjct: 412 PTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRV 471
Query: 534 ANSLTTGNVAINDFATFYVCQLPFGGL 560
+L G V +N+ PFGG+
Sbjct: 472 FEALEYGLVGVNE-GLISTEVAPFGGV 497
>Hs10835045 [C] KOG2450 Aldehyde dehydrogenase
Length = 518
Score = 166 bits (420), Expect = 1e-40
Identities = 129/461 (27%), Positives = 209/461 (44%), Gaps = 27/461 (5%)
Query: 103 NPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLL 159
N E + Y PATG+ + + DID+ V A A W + ER ++L
Sbjct: 48 NSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSVWRRMDASERGRLLD 107
Query: 160 SLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPT 219
L + + ++ +A + + GK L A ++ ++ ++ D + P
Sbjct: 108 KLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA-DKIHGMTIPVDG 166
Query: 220 NFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSK 279
++F R+EP+GV G I+ WN+P I ++ GN VV+K +EQ S+
Sbjct: 167 DYF------TFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSAL 220
Query: 280 FFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVL 339
+ L++EA G P ++ + PT A SH + F GS V +
Sbjct: 221 YMGALIKEA----GFPPGVINILPGYGPT----AGAAIASHIGIDKIAFTGSTEVGKLIQ 272
Query: 340 KAAADS-LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAK 398
+AA S L V +ELGGK I+ DL +G F + GQ C R+ V
Sbjct: 273 EAAGRSNLKRVTLELGGKSPNIIFADA-DLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331
Query: 399 NYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGG 458
Y+ V +R + +GS D + G I ++ ++ LI +++GAKL GG
Sbjct: 332 IYEEFVRRSVERAKRRIVGSPFD--PTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGG 389
Query: 459 SRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGL 518
+G F +PT+ +VT+DM+I+ E+FGP+ ++R K D+ I AN + FGL
Sbjct: 390 KGLGR----KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 445
Query: 519 GGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
++F D + V++++ G V IN + Q PFGG
Sbjct: 446 VAAVFTNDINKALTVSSAMQAGTVWINCYNALN-AQSPFGG 485
>At3g48170 [C] KOG2450 Aldehyde dehydrogenase
Length = 503
Score = 166 bits (419), Expect = 1e-40
Identities = 121/452 (26%), Positives = 214/452 (46%), Gaps = 27/452 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQ-----WAKTSLKERLQVLLSLKNFILENQ 169
PAT +G + + D++ V A +A + WA+ + R + L ++ ++E +
Sbjct: 30 PATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDWARATGAVRAKYLRAIAAKVIERK 89
Query: 170 EAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLK--PSARPGPTNFFMKWYK 227
+A + D GK + +A+ ++ + E+ D+ + + + P + M +K
Sbjct: 90 SELANLEAIDCGKPLDEAAWD-----MDDVAGCFEYYADLAEGLDAKQKTPLSLPMDTFK 144
Query: 228 GAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQE 287
G ++ EP+GVVG I WNYP + + S+ G ++K SE + L + +
Sbjct: 145 GYILK-EPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPSEL----ASLTCLELAD 199
Query: 288 ALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLT 347
+ G P ++ + L +A SHP + F GS ++ +AA +
Sbjct: 200 ICREVGLPPGVLNILTGL----GTEAGAPLASHPHVDKIVFTGSTTTGSSIMTSAAKLVK 255
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
PV +ELGGK IV D V D+ M G F + GQ C R++V + D + L
Sbjct: 256 PVSLELGGKSPIIVFDDV-DIDKAVEWTMFGCFWTNGQICSATSRLLVHERIADEFLDKL 314
Query: 408 NDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYP 467
+++ + E +G ++S ++ ++ +S+A ++GA +L GG R H
Sbjct: 315 VKWTKNIKISDPFE--EGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGVRPEH--LK 370
Query: 468 QGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADF 527
+G+F +P ++ +VT M+I EVFGP L V D+ I+LAN + +GL G++ D
Sbjct: 371 KGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAGAVLSNDL 430
Query: 528 GECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
C+RV+ + G V +N + CQ P+GG
Sbjct: 431 ERCDRVSKAFQAGIVWVNCSQPCF-CQAPWGG 461
>Hs4502041 [C] KOG2450 Aldehyde dehydrogenase
Length = 512
Score = 165 bits (418), Expect = 2e-40
Identities = 128/484 (26%), Positives = 226/484 (46%), Gaps = 41/484 (8%)
Query: 80 KLYIPDAAHKHWKGKRMFPCSVYNPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLA 139
K++I + H+ GK+ C+ P+T + + + D+D+ V A
Sbjct: 33 KIFINNEWHESKSGKKFATCN--------------PSTREQICEVEEGDKPDVDKAVEAA 78
Query: 140 ERAQLQ---WAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTL 196
+ A + W + R ++L L + + ++ +A + D+GK L A ++ +
Sbjct: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138
Query: 197 EKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPI 256
+++ + + + PT+ + + R+EP+GV GAI WN+P L+ +
Sbjct: 139 RTLRYFAGWADKI---QGKTIPTDDNVVCF----TRHEPIGVCGAITPWNFPLLMLVWKL 191
Query: 257 VASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANY 316
++ GN +V+K +EQ ++ + L++EA G P +V + PT
Sbjct: 192 APALCCGNTMVLKPAEQTPLTALYLGSLIKEA----GFPPGVVNIVPGFGPT----VGAA 243
Query: 317 FTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVVVELGGKDAFIVLDSVKDLQALSSII 375
+SHP + F GS V V +AA+ S L V +ELGGK+ IV DL
Sbjct: 244 ISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA-DLDLAVECA 302
Query: 376 MRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDN 435
+G F + GQ C RV V + Y V + + +G D + G I
Sbjct: 303 HQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFD--VKTEQGPQIDQK 360
Query: 436 RFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPI 495
+F ++ LI +GAKL GGS +G F +PT+ +VT++M+I+ E+FGP+
Sbjct: 361 QFDKILELIESGKKEGAKLECGGSAMED----KGLFIKPTVFSEVTDNMRIAKEEIFGPV 416
Query: 496 LTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQL 555
+++ K ++ I+ AN+ +GL ++F + + ++A++L +G V IN + Y Q
Sbjct: 417 QPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALY-AQA 475
Query: 556 PFGG 559
PFGG
Sbjct: 476 PFGG 479
>At2g24270 [C] KOG2450 Aldehyde dehydrogenase
Length = 496
Score = 164 bits (416), Expect = 3e-40
Identities = 129/450 (28%), Positives = 218/450 (47%), Gaps = 30/450 (6%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
PAT + ++ + +++ ++ LA+ AQ WAKT L +R ++L + +N+ +A
Sbjct: 38 PATRKTQYKVQACTQEEVNAVMELAKSAQKSWAKTPLWKRAELLHKAAAILKDNKAPMAE 97
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPS----ARPGPTNFFMKWYKGAE 230
++ K D S+ E++ + + I + E G +L + P N K+ ++
Sbjct: 98 SLVKEIAKPAKD-SVTEVVRSGDLISYCAEEGVRILGEGKFLLSDSFPGNDRTKYCLTSK 156
Query: 231 VRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALK 290
+ PLGVV AI +NYP + + I ++ GN++V+K Q S L +
Sbjct: 157 I---PLGVVLAIPPFNYPVNLAVSKIAPALIAGNSLVLKPPTQGAVSC----LHMVHCFH 209
Query: 291 ACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVV 350
G L+ C+ G++ ++ T HP ++F G KA + P+
Sbjct: 210 LAGFPKGLIS---CITGKGSE-IGDFLTMHPAVNCISFTGGDTGISISKKAG---MIPLQ 262
Query: 351 VELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDR 410
+ELGGKDA IVLD DL ++S I++G F +GQ C ++ V+V D LV + +
Sbjct: 263 MELGGKDACIVLDDA-DLDLVASNIIKGGFSYSGQRCTAVKVVLVMESVADELVEKVKAK 321
Query: 411 VGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGH 470
V +L +G +N D+ A++S++ +E L+ DA KGA R +G+
Sbjct: 322 VAKLTVGPPEENS---DITAVVSESSANFIEGLVMDAKEKGATFCQEYKR-------EGN 371
Query: 471 FFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGEC 530
P LL +V DM+I+ E FGP++ V+R ++ I NA+ FGL G +F D +
Sbjct: 372 LIWPLLLDNVRPDMRIAWEEPFGPVVPVLRINSVEEGINHCNASNFGLQGCVFTKDINKA 431
Query: 531 NRVANSLTTGNVAINDFATFYVCQLPFGGL 560
+++++ TG V IN PF GL
Sbjct: 432 ILISDAMETGTVQINSAPARGPDHFPFQGL 461
>7297513 [C] KOG2450 Aldehyde dehydrogenase
Length = 520
Score = 164 bits (415), Expect = 4e-40
Identities = 125/454 (27%), Positives = 208/454 (45%), Gaps = 37/454 (8%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLLSLKNFILENQEA 171
P T + + + DID V A A W + ER ++L L + + +Q
Sbjct: 62 PTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVY 121
Query: 172 IARVACRDSGKTMLDASMGEILVTLEKIQWII-----EHGEDVLKPSARPGPTNFFMKWY 226
+A + D+GK + ++ ++ +++ HG+ + P +FF
Sbjct: 122 LASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTI------PMDGDFF---- 171
Query: 227 KGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQ 286
R+EP+GV G I+ WN+P + + ++ TGN +V+K +EQ ++ + LV+
Sbjct: 172 --TYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVK 229
Query: 287 EALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS- 345
EA G +V + +P G AA +H + F GS V + A+ ++
Sbjct: 230 EA----GFPEGVVNV---VPGFGTAGAA--LANHCDVDKVAFTGSTDVGKLIQLASGNTN 280
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
L V +ELGGK I+L D+ G F + GQ C R V K YD V
Sbjct: 281 LKRVTLELGGKSPNIILSDT-DMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVE 339
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
+R + +G+ D + + G +++ + ++ +I +GAKL+ GGSR P
Sbjct: 340 RSAERAKKRTVGNPFDL--NTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSR---PE 394
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGA 525
G+F QPT+ DV +DM I+ E+FGP+ ++R K D+ I AN + +GL ++F
Sbjct: 395 GLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTK 454
Query: 526 DFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
D + N + L G V +N + Q PFGG
Sbjct: 455 DLDKANYIVGGLRAGTVWVNTY-NVLAAQAPFGG 487
>YPL061w [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 162 bits (410), Expect = 1e-39
Identities = 123/450 (27%), Positives = 218/450 (48%), Gaps = 28/450 (6%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P+T + S + D++ + A+RA +WA +ER ++L L + + + +
Sbjct: 48 PSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLV 107
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVR 232
+ + D+GKT L + G++ + + ++ + + V + G + +M +
Sbjct: 108 SSIEALDNGKT-LALARGDVTIAINCLRDAAAYADKVNGRTINTG--DGYMNF-----TT 159
Query: 233 YEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKAC 292
EP+GV G I+ WN+P L I ++ GN ++K + ++ +F L K
Sbjct: 160 LEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLC----KKV 215
Query: 293 GHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVVV 351
G +V + +P G A T+ P + L F GS V V +++S L + +
Sbjct: 216 GIPAGVVNI---VPGPGRTVGAA-LTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITL 271
Query: 352 ELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRV 411
ELGGK A +V D + L +++ G F++AGQ C R+ V YD L++ +
Sbjct: 272 ELGGKSAHLVFDDANIKKTLPNLV-NGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYL 330
Query: 412 G-QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGH 470
++++G+ D GA+ + +F + N I +GAK+L GG + +G+
Sbjct: 331 ETEIKVGNPFDKANF--QGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGD----KGY 384
Query: 471 FFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGEC 530
F +PT+ DV EDM+I E+FGP++TV + K ++ + +AN++ FGLG I
Sbjct: 385 FIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTG 444
Query: 531 NRVANSLTTGNVAINDFATFYVCQLPFGGL 560
+VA L G V IN + F ++PFGG+
Sbjct: 445 LKVAKMLKAGTVWINTYNDF-DSRVPFGGV 473
>YMR170c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 160 bits (405), Expect = 6e-39
Identities = 126/458 (27%), Positives = 211/458 (45%), Gaps = 29/458 (6%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERA-QLQWAKTSLKERLQVLLSLKNFILEN 168
I++ PATG+ + SF++ ++ D+D+ V A A W+KTS ++R L +L I E
Sbjct: 38 IETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEE 97
Query: 169 QEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKG 228
Q+ +A + D+GK + G++ L+ ++ + K + P N F K
Sbjct: 98 QDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFNKFAYTLK- 156
Query: 229 AEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEA 288
P GVV IV WNYP + ++ GN V++K +E S +F L+++A
Sbjct: 157 -----VPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKA 211
Query: 289 LKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LT 347
G P +V + P SH ++F GS V VL+A+ S L
Sbjct: 212 ----GFPPGVVNIV----PGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLK 263
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
V +E GGK +V + DL I G F ++GQNC RV V + YD V
Sbjct: 264 DVTLECGGKSPALVFEDA-DLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKF 322
Query: 408 NDRVG-QLRLGSDIDNLED-VDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
+ + + D ++ +G +IS ++ ++++ I + KL +
Sbjct: 323 KETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERG-KREEKL----DMFQTSE 377
Query: 466 YP----QGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGS 521
+P +G+F PT+ DV + ++ +E+FGP++ V + + DD ++LAN +GL +
Sbjct: 378 FPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASA 437
Query: 522 IFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
+F D + + A + G V IN V +PFGG
Sbjct: 438 VFTKDVKKAHMFARDIKAGTVWINSSNDEDV-TVPFGG 474
>HsM7110595 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 159 bits (403), Expect = 9e-39
Identities = 130/482 (26%), Positives = 213/482 (43%), Gaps = 34/482 (7%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P G + TD+D+ V A+ A +W K S ++R +++ L + + ++QE +
Sbjct: 444 PTDGSVICQVSLAQVTDVDKAVAAAKGAFENGRWGKISARDRGRLMYRLADLMEQHQEEL 503
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWYK 227
A + D+G A + ++++ ++ G + ARP N +
Sbjct: 504 ATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPN-RNLTL---- 558
Query: 228 GAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQE 287
R EP+GV G I+ WNYP L A + GN VV+K ++ ++ F L +
Sbjct: 559 ---TRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLK 615
Query: 288 ALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-L 346
A G +V + LP +G+ + HP + + F GS V H++K+ A S +
Sbjct: 616 A----GIPKGVVNV---LPGSGSL-VGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNV 667
Query: 347 TPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSI 406
V +ELGG+ FI+ DL + M F S G+NCI R+ V +D V
Sbjct: 668 KKVSLELGGESPFIIFADC-DLNKAVQMGMSSVFFSKGENCIAAGRLFVEDSIHDEFVRR 726
Query: 407 LNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNY 466
+ + V ++++G+ +D D D G +L + +GA L+ GG++ P
Sbjct: 727 VVEEVRKMKVGNPLD--RDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRP-- 782
Query: 467 PQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAK--DTDDCIRLANAAPFGLGGSIFG 524
G FF+PT+ DV + M I+ E FGP++ + R D D + ANA FGL +F
Sbjct: 783 --GFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFT 840
Query: 525 ADFGECNRVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVC 584
D + V++ L G V +N + V PFGG K+V
Sbjct: 841 RDINKALYVSDKLQAGTVFVNTYNKTDVA-APFGGFKQSGFGKDLGEAALNEYLRVKTVT 899
Query: 585 FD 586
F+
Sbjct: 900 FE 901
>At3g48000 [C] KOG2450 Aldehyde dehydrogenase
Length = 538
Score = 159 bits (401), Expect = 2e-38
Identities = 124/448 (27%), Positives = 198/448 (43%), Gaps = 26/448 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P TG+ + DI+ V A A + W K S ER +VLL + + ++ E +
Sbjct: 80 PRTGEVIAHVAEGDAEDINRAVKAARTAFDEGPWPKMSAYERSRVLLRFADLVEKHSEEL 139
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVR 232
A + D+GK + EI + ++ D + P N+ +
Sbjct: 140 ASLETWDNGKPYQQSLTAEIPMFARLFRYYAGWA-DKIHGLTIPADGNYQV------HTL 192
Query: 233 YEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKAC 292
+EP+GV G I+ WN+P + ++ GN +V+K +EQ ++ + L EA
Sbjct: 193 HEPIGVAGQIIPWNFPLLMFAWKVGPALACGNTIVLKTAEQTPLTAFYAGKLFLEA---- 248
Query: 293 GHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVVV 351
G P ++ + T A SH L F GS +L AA+S L PV +
Sbjct: 249 GLPPGVLNIVSGFGAT----AGAALASHMDVDKLAFTGSTDTGKVILGLAANSNLKPVTL 304
Query: 352 ELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRV 411
ELGGK FIV + D+ + F + GQ C R V K YD V R
Sbjct: 305 ELGGKSPFIVFEDA-DIDKAVELAHFALFFNQGQCCCAGSRTFVHEKVYDEFVEKSKARA 363
Query: 412 GQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHF 471
+ +G + ++ G I +F ++ I + A L GG + +G+F
Sbjct: 364 LKRVVGDPFR--KGIEQGPQIDLKQFEKVMKYIKSGIESNATLECGGDQIGD----KGYF 417
Query: 472 FQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECN 531
QPT+ +V +DM I+ +E+FGP+ ++++ D D+ I+ AN +GL +F + N
Sbjct: 418 IQPTVFSNVKDDMLIAQDEIFGPVQSILKFSDVDEVIKRANETKYGLAAGVFTKNLDTAN 477
Query: 532 RVANSLTTGNVAINDFATFYVCQLPFGG 559
RV+ +L G V +N F F +PFGG
Sbjct: 478 RVSRALKAGTVWVNCFDVFDAA-IPFGG 504
>CE24573 [C] KOG2450 Aldehyde dehydrogenase
Length = 574
Score = 158 bits (399), Expect = 3e-38
Identities = 138/511 (27%), Positives = 231/511 (45%), Gaps = 52/511 (10%)
Query: 63 IYQWVFSKSKL----PSAVQFKLYIPDAAHKHWKGKRMFPCSVYNPEQPHMIQSYCPATG 118
++ +FS SK+ PS + LY + GKR ++ + E +I+ P G
Sbjct: 66 VFNTIFSVSKMVFTVPSDLSGGLYFLN-------GKRT---TIESTETFDVIE---PRIG 112
Query: 119 QFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACR 178
Q + + +D+ V A AQ W +T+ +R +VL + + I E+ E IA +
Sbjct: 113 QVVAKCPKATADIVDQYVKAAADAQSAWGETTALDRGKVLHKVADLIREHAEEIAIWEVK 172
Query: 179 DSGKTMLDA-----SMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRY 233
+GK + +A S + I + G+ + P GP+ + A R
Sbjct: 173 TNGKPIYEARCDIASSADTFDFFGGIATAVLQGDSLELPG---GPSQ------RIAYTRR 223
Query: 234 EPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACG 293
EP GVVG I +WNYPF + + ++ GNAVV K S S +L+ E L A G
Sbjct: 224 EPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPASP----VLLGEILTAAG 279
Query: 294 HDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLK-AAADSLTPVVVE 352
+ + G +A H + ++F GS V + AA ++ PV +E
Sbjct: 280 VPKGVYNVIQ-----GEQEAGVALCEHNLVAKVSFTGSVASGEAVQRQAATKNVKPVTLE 334
Query: 353 LGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVS----AKNYDALVSILN 408
LGGK I+ D D+++ + M F + GQ C RV V A +A+V N
Sbjct: 335 LGGKSEIIIFDD-SDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFTEAIVQEAN 393
Query: 409 DRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQ 468
D+ L++G + LED +GA I++ ++ + A +G +L GG R +
Sbjct: 394 DK---LKVGDPL--LEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHPTGVEG 448
Query: 469 GHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFG 528
G +F+P ++ ++++ + E+FG ++ ++ + ++ I AN +GL +F +
Sbjct: 449 GAYFEPAIITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAGVFSGNLA 508
Query: 529 ECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
+RVA L G V IN + V +PFGG
Sbjct: 509 RGHRVAARLQAGTVFINTYNDTEV-NVPFGG 538
>Hs21614513 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 902
Score = 157 bits (398), Expect = 4e-38
Identities = 129/482 (26%), Positives = 212/482 (43%), Gaps = 34/482 (7%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P G + TD+D+ V A+ A +W K S ++R +++ L + + ++QE +
Sbjct: 444 PTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEEL 503
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWYK 227
A + D+G A + ++++ ++ G + ARP N +
Sbjct: 504 ATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPN-RNLTL---- 558
Query: 228 GAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQE 287
R EP+GV G I+ WNYP L A + GN VV+K ++ ++ F L +
Sbjct: 559 ---TRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLK 615
Query: 288 ALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-L 346
A G +V + LP +G+ + HP + + F GS V H++K+ A S +
Sbjct: 616 A----GIPKGVVNV---LPGSGSL-VGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNV 667
Query: 347 TPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSI 406
V +ELGGK I+ DL + M F + G+NCI R+ V +D V
Sbjct: 668 KKVSLELGGKSPLIIFADC-DLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRR 726
Query: 407 LNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNY 466
+ + V ++++G+ +D D D G +L + +GA L+ GG++ P
Sbjct: 727 VVEEVRKMKVGNPLD--RDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRP-- 782
Query: 467 PQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAK--DTDDCIRLANAAPFGLGGSIFG 524
G FF+PT+ DV + M I+ E FGP++ + R D D + ANA FGL +F
Sbjct: 783 --GFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFT 840
Query: 525 ADFGECNRVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVC 584
D + V++ L G V +N + V PFGG K+V
Sbjct: 841 RDINKALYVSDKLQAGTVFVNTYNKTDVA-APFGGFKQSGFGKDLGEAALNEYLRVKTVT 899
Query: 585 FD 586
F+
Sbjct: 900 FE 901
>At1g23800 [C] KOG2450 Aldehyde dehydrogenase
Length = 508
Score = 157 bits (397), Expect = 5e-38
Identities = 122/448 (27%), Positives = 200/448 (44%), Gaps = 26/448 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P G+ + D++ V A +A + W K + ER ++L + I ++ + I
Sbjct: 50 PRNGEVIAQVSEGDAEDVNRAVAAARKAFDEGPWPKMTAYERSKILFRFADLIEKHNDEI 109
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVR 232
A + D+GK ++ E+ + L ++ D + PG + +
Sbjct: 110 AALETWDNGKPYEQSAQIEVPM-LARVFRYYAGWADKIHGMTMPGDGPHHV------QTL 162
Query: 233 YEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKAC 292
+EP+GV G I+ WN+P L + ++ GN VV+K +EQ S+ LLV + L
Sbjct: 163 HEPIGVAGQIIPWNFPLLMLSWKLGPALACGNTVVLKTAEQTPLSA----LLVGKLLHEA 218
Query: 293 GHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVVV 351
G +V + T A SH + F GS V +L+ A+ S L V +
Sbjct: 219 GLPDGVVNIVSGFGAT----AGAAIASHMDVDKVAFTGSTDVGKIILELASKSNLKAVTL 274
Query: 352 ELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRV 411
ELGGK FIV + D+ + F + GQ C R V + YD V R
Sbjct: 275 ELGGKSPFIVCEDA-DVDQAVELAHFALFFNQGQCCCAGSRTFVHERVYDEFVEKAKARA 333
Query: 412 GQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHF 471
+ +G + ++ G + +F ++ I + GA L GG R +G++
Sbjct: 334 LKRNVGDPFKS--GIEQGPQVDSEQFNKILKYIKHGVEAGATLQAGGDRLGS----KGYY 387
Query: 472 FQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECN 531
QPT+ DV +DM I+ +E+FGP+ T+++ KD D+ I AN + +GL +F + +
Sbjct: 388 IQPTVFSDVKDDMLIATDEIFGPVQTILKFKDLDEVIARANNSRYGLAAGVFTQNLDTAH 447
Query: 532 RVANSLTTGNVAINDFATFYVCQLPFGG 559
R+ +L G V IN F +PFGG
Sbjct: 448 RLMRALRVGTVWINCFDVL-DASIPFGG 474
>Hs19923115 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 156 bits (395), Expect = 8e-38
Identities = 121/454 (26%), Positives = 199/454 (43%), Gaps = 37/454 (8%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLLSLKNFILENQEA 171
P TG+ +G D+D V A A W + ER ++L L + + ++
Sbjct: 59 PTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVERDRVY 118
Query: 172 IARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWY 226
+A + D+GK ++ ++ ++ ++ HG+ + P F
Sbjct: 119 LASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTI------PMDGQHF---- 168
Query: 227 KGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQ 286
R+EP+GV G I+ WN+P + ++ TGN VV+K +EQ S+ + L++
Sbjct: 169 --CFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIK 226
Query: 287 EALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS- 345
EA G P +V + PT A H + F GS V H + KAA DS
Sbjct: 227 EA----GFPPGVVNIITGYGPT----AGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSN 278
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
L V +ELGGK IVL D++ F + GQ C R V Y+ +
Sbjct: 279 LKRVTLELGGKSPSIVLADA-DMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLE 337
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
++ Q ++G+ + D G + +F ++ I +GAKLL GG R+
Sbjct: 338 RTVEKAKQRKVGNPFEL--DTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGE-- 393
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGA 525
+G F +PT+ V +DM+I+ E+FGP+ + + K ++ + AN +GL ++F
Sbjct: 394 --RGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTR 451
Query: 526 DFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
D + +L G V +N + C PFGG
Sbjct: 452 DLDKAMYFTQALQAGTVWVNTY-NIVTCHTPFGG 484
>Hs18579349 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 975
Score = 156 bits (395), Expect = 8e-38
Identities = 120/456 (26%), Positives = 203/456 (44%), Gaps = 34/456 (7%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
P G + S D+D+ V A+ A +W + + +ER +++ L + + ENQE +
Sbjct: 465 PTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEEL 524
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWYK 227
A + DSG A I ++++ ++ G + ARP F K
Sbjct: 525 ATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTK--- 581
Query: 228 GAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQE 287
EPLGV I+ WNYP L A + GN +V+K ++ ++ F L +
Sbjct: 582 -----KEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVK 636
Query: 288 ALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKA-AADSL 346
A G ++ + P A + HP + L F GS P+ ++K+ A +L
Sbjct: 637 A----GFPKGVINII----PGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNL 688
Query: 347 TPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSI 406
V +ELGGK I+ + +L + M F + G+NCI R+ V +D V+
Sbjct: 689 KKVSLELGGKSPLIIFNDC-ELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTR 747
Query: 407 LNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNY 466
+ + + ++++G +D D G +L + +GA L++GG + P
Sbjct: 748 VVEEIKKMKIGDPLD--RSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRP-- 803
Query: 467 PQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAK--DTDDCIRLANAAPFGLGGSIFG 524
G F +PT+ DV + M ++ E FGPI+ + + + D D ++ AN+ +GL +F
Sbjct: 804 --GFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFT 861
Query: 525 ADFGECNRVANSLTTGNVAINDFATFYVCQLPFGGL 560
D + V+ L G V IN + V PFGG+
Sbjct: 862 RDINKAMYVSEKLEAGTVFINTYNKTDVA-APFGGV 896
>SPCC550.10 [C] KOG2450 Aldehyde dehydrogenase
Length = 500
Score = 154 bits (390), Expect = 3e-37
Identities = 118/435 (27%), Positives = 203/435 (46%), Gaps = 21/435 (4%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQ--WAKTSLKERLQVLLSLKNFILENQEAI 172
PAT + +G+ + S D+D V A WAK K+R VL + + E +E +
Sbjct: 45 PATEEIIGTCANASAKDVDSAVENAYNTFRSGIWAKWPGKQRGLVLRKIAKMMREKRELL 104
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVR 232
A + + GK A + +I + ++ E E P P N + E R
Sbjct: 105 AGIDTINCGKPTPYA-LFDIDSCADMFEYYAEVAETDNPTVKVPLPNN---PGFCAFEKR 160
Query: 233 YEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKAC 292
+ P GV+G I WN+P L +V +I +GN VV+K SE WS F L+ +EA
Sbjct: 161 F-PRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELAPWSCLEFALICKEAGLPD 219
Query: 293 GHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVE 352
G + + +G + A + HP +L F GS ++ AAA+++ P+ +E
Sbjct: 220 G-------VLNVIIGSGKESGAA-LSCHPKIAYLAFTGSLATGKKIMHAAAENIVPLTLE 271
Query: 353 LGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVG 412
LGGK I+ + A+ S F + G+ C R+IV D ++ L
Sbjct: 272 LGGKSPLIICEDADLSLAIPSAAF-AIFFNQGEACTAASRLIVHESVADEVLGGLVSEAN 330
Query: 413 QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFF 472
+L +G+ +D V +G ++S +F ++ + I A+++G K + GG + +G+F
Sbjct: 331 KLIIGNGLD--PQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLPRSEQ---KGYFI 385
Query: 473 QPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNR 532
PT+ +V +I E+FGP+L V ++ + LAN + +GLG +F +
Sbjct: 386 PPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGLGSGVFSTNPKTLEF 445
Query: 533 VANSLTTGNVAINDF 547
+N++ G ++N++
Sbjct: 446 FSNNIEAGMCSLNNY 460
>Hs12007648 [C] KOG2450 Aldehyde dehydrogenase
Length = 487
Score = 152 bits (383), Expect = 2e-36
Identities = 118/472 (25%), Positives = 213/472 (45%), Gaps = 34/472 (7%)
Query: 95 RMFPCSVYNPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKER 154
+ PCS Y I SY P+TG+ + +I+ V A A W+ S +ER
Sbjct: 17 KFLPCSSY-------IDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQER 69
Query: 155 LQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIE---HGEDVLK 211
+VL + + + ++ E A+ +D GKT+ A +I +++ ++ H
Sbjct: 70 SRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECT 129
Query: 212 PSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCS 271
G ++ ++ P+GV G I WN P + L I ++ GN V+ K S
Sbjct: 130 QMDHLGCMHYTVR---------APVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPS 180
Query: 272 EQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGS 331
E ++ L+ +A G P +V + + P SHP ++F GS
Sbjct: 181 ELTSVTAWMLCKLLDKA----GVPPGVVNIVFGTGPR----VGEALVSHPEVPLISFTGS 232
Query: 332 KPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIE 391
+P A + + +A + +ELGGK+ I+ + +L +R +F + G+ C+
Sbjct: 233 QPTAERITQLSAPHCKKLSLELGGKNPAIIFEDA-NLDECIPATVRSSFANQGEICLCTS 291
Query: 392 RVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKG 451
R+ V Y + + + ++G D L V +GA+IS ++ + + AL++G
Sbjct: 292 RIFVQKSIYSEFLKRFVEATRKWKVGIPSDPL--VSIGALISKAHLEKVRSYVKRALAEG 349
Query: 452 AKLL--HGGSRYNHPNYPQ-GHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCI 508
A++ G + + P Q G+F PT++ D+ ++ E+FGP+ V+ ++ I
Sbjct: 350 AQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVI 409
Query: 509 RLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGGL 560
AN +GL +++ ++ G +RVA L +G V N + LPFGG+
Sbjct: 410 ERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCW-LIRELNLPFGGM 460
>Hs11436533 [C] KOG2450 Aldehyde dehydrogenase
Length = 517
Score = 152 bits (383), Expect = 2e-36
Identities = 122/454 (26%), Positives = 209/454 (45%), Gaps = 37/454 (8%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA-QL--QWAKTSLKERLQVLLSLKNFILENQEA 171
P+TG+ + D+D+ V A A QL W + R ++L L + I ++
Sbjct: 59 PSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTY 118
Query: 172 IARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWY 226
+A + D+GK + + + ++ + L+ +++ HG+ + P +FF
Sbjct: 119 LAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTI------PIDGDFF---- 168
Query: 227 KGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQ 286
+ R+EP+GV G I+ WN+P + ++ TGN VV+K +EQ ++ + L++
Sbjct: 169 --SYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIK 226
Query: 287 EALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS- 345
EA G P +V + PT A SH + F GS + + AA S
Sbjct: 227 EA----GFPPGVVNIVPGFGPT----AGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSN 278
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
L V +ELGGK I++ D+ F + GQ C R V YD V
Sbjct: 279 LKRVTLELGGKSPNIIMSDA-DMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVE 337
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
R +G+ D+ + G + + +F ++ I+ +GAKLL GG
Sbjct: 338 RSVARAKSRVVGNPFDS--KTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAAD-- 393
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGA 525
+G+F QPT+ DV + M I+ E+FGP++ +++ K ++ + AN + +GL ++F
Sbjct: 394 --RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 526 DFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
D + N ++ +L G V +N + F Q PFGG
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVF-GAQSPFGG 484
>CE23852 [C] KOG2450 Aldehyde dehydrogenase
Length = 537
Score = 152 bits (383), Expect = 2e-36
Identities = 118/449 (26%), Positives = 204/449 (45%), Gaps = 27/449 (6%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLLSLKNFILENQEA 171
PA G+ L + D+D V A++A +W + R +L L + + ++
Sbjct: 79 PANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDASHRGVLLNRLADLMERDRVI 138
Query: 172 IARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEV 231
+A + D+GK +A ++ ++++ ++ + + + G F
Sbjct: 139 LASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHGKTIPVGGDYF-------TYT 191
Query: 232 RYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKA 291
R+EP+GV G I+ WN+P + ++ GN VV+K + + S+ L++EA
Sbjct: 192 RHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSALHVASLIKEAQFP 251
Query: 292 CGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVV 350
G + +P G D A SH + F GS V ++KAAA+S + V
Sbjct: 252 EG-------VVNIIPGRGTD-AGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESNVKKVT 303
Query: 351 VELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDR 410
+ELGGK IV DL+ F + GQ C R V K YD V+ +
Sbjct: 304 LELGGKSPNIVFADA-DLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVAKAKEL 362
Query: 411 VGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGH 470
V + +G D E+ G I +++ + I +GA+L+ GG ++ QG+
Sbjct: 363 VEKTVIGDPFD--ENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGD----QGY 416
Query: 471 FFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGEC 530
F +PT+ +V + M+I+ E+FGP++ V+R ++ I AN +GL + D +
Sbjct: 417 FVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNKA 476
Query: 531 NRVANSLTTGNVAINDFATFYVCQLPFGG 559
+VAN++ G+V +N + F PFGG
Sbjct: 477 LQVANTIRAGSVWVNCYDVFDPA-APFGG 504
>Hs11095441 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 535
Score = 151 bits (382), Expect = 3e-36
Identities = 110/436 (25%), Positives = 201/436 (45%), Gaps = 20/436 (4%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQ 169
I + PAT + +G + ++D + +RA WA TS+ R QVLL + I EN
Sbjct: 57 IDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENL 116
Query: 170 EAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGA 229
+ IA++ + GKT+ DA G++ L+ ++EH V S G T +
Sbjct: 117 KEIAKLITLEQGKTLADAE-GDVFRGLQ----VVEHACSVT--SLMMGETMPSITKDMDL 169
Query: 230 EVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEAL 289
PLGV I +N+P L ++ GN ++K SE+V + T+L+ + L
Sbjct: 170 YSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGA----TMLLAKLL 225
Query: 290 KACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPV 349
+ G + + + G +A N+ HP K ++F+GS ++ + + V
Sbjct: 226 QDSGAPDGTLNIIH-----GQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRV 280
Query: 350 VVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILND 409
+G K+ +V+ L+ ++ F +AGQ C+ + ++ + L ++ +
Sbjct: 281 QANMGAKNHGVVMPDANKENTLNQLV-GAAFGAAGQRCMALSTAVLVGEAKKWLPELV-E 338
Query: 410 RVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQG 469
LR+ + + D+G +I+ ++ NLI +GA +L G + Y G
Sbjct: 339 HAKNLRVNAG--DQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENG 396
Query: 470 HFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGE 529
+F PT++ +V +M E+FGP+L V+ + D+ I++ N P+G G +IF +
Sbjct: 397 NFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGAT 456
Query: 530 CNRVANSLTTGNVAIN 545
+ A+ + G V +N
Sbjct: 457 ARKYAHLVDVGQVGVN 472
>CE10542 [C] KOG2451 Aldehyde dehydrogenase
Length = 569
Score = 150 bits (380), Expect = 4e-36
Identities = 117/421 (27%), Positives = 188/421 (43%), Gaps = 29/421 (6%)
Query: 145 QWAKT-SLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWII 203
+WA T S K+R +L +++ + +A + ++ GK + +A GEI + W
Sbjct: 70 KWAHTYSAKQRGAILHKWFEILVQRETELATLLTKEQGKPLAEAR-GEIQYSAAYFDWYA 128
Query: 204 EHGEDV---LKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASI 260
V + PSA + + EP+GVV I WN+P + A++
Sbjct: 129 GEARRVYGQVVPSAVVNRLHLHTR---------EPIGVVALIAPWNFPTAMIARKAAAAL 179
Query: 261 FTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSH 320
G + VVK S S+ +EA G V + + + Y
Sbjct: 180 SVGCSAVVKPSGDTPLSALALAQTAEEAGIPAG-----VFNVITADHSNTAEISKYLCES 234
Query: 321 PVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTF 380
++F GS PV +L +A ++ V +ELGG IV D DL + M F
Sbjct: 235 TDVSAISFTGSTPVGKLLLAQSASTVKRVCLELGGNAPLIVFDDA-DLDVAVNGTMATKF 293
Query: 381 QSAGQNCIGIERVIVSAKNYDALVSILNDRVGQ-LRLGSDIDNLEDVDMGAMISDNRFGQ 439
+ +GQ C+ R+ V K +D +S L + + L LG ++ G +++ +
Sbjct: 294 RCSGQTCVSANRIYVHEKIHDQYISKLAAAMKEKLVLGDGLN--PKTTQGPLVNQKAVDK 351
Query: 440 LENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVM 499
E L+SDAL KG++L+ GG R H G ++PTL+ +V + I+H E+FGPI +V
Sbjct: 352 CELLLSDALGKGSELICGGKRGEH-----GTSYEPTLITNVQSNTNIAHTEIFGPIASVQ 406
Query: 500 RAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
+ +D + + AN GL G +FG D RVA L G V +N+ + FGG
Sbjct: 407 KFRDEQEVLEAANNCRVGLAGYVFGRDQSRLQRVARKLEVGMVGVNE-GLISCAEAAFGG 465
Query: 560 L 560
+
Sbjct: 466 V 466
>YMR169c [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 150 bits (378), Expect = 7e-36
Identities = 121/458 (26%), Positives = 207/458 (44%), Gaps = 29/458 (6%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERA-QLQWAKTSLKERLQVLLSLKNFILEN 168
I++ PATG+ + SF++ ++ D+D+ V A A W+KTS ++R L +L I E
Sbjct: 38 IETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEE 97
Query: 169 QEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKG 228
Q+ +A + D+GK + ++ +E ++ + P N F K
Sbjct: 98 QDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFNKFAYTLK- 156
Query: 229 AEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEA 288
P GVV IV WNYP + ++ GN V++K +E S +F L+++A
Sbjct: 157 -----VPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKA 211
Query: 289 LKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LT 347
G P +V + P +H ++F GS V VL+A+ S L
Sbjct: 212 ----GFPPGVVNVI----PGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLK 263
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
+ +E GGK +V + DL + G F ++GQ C RV V + YD V
Sbjct: 264 DITLECGGKSPALVFEDA-DLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKF 322
Query: 408 NDRVG-QLRLGSDIDNLED-VDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
+ + + D ++ +G +IS ++ ++++ I K KL +
Sbjct: 323 KETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERG-KKEEKL----DMFQTSE 377
Query: 466 YP----QGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGS 521
+P +G+F PT+ DV E ++ +E+FGP++ V + + DD ++LAN +GL +
Sbjct: 378 FPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASA 437
Query: 522 IFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
+F D + + A + G V IN ++PFGG
Sbjct: 438 VFTKDVKKAHMFARDIKAGTVWINQ-TNQEEAKVPFGG 474
>SPAC139.05 [C] KOG2451 Aldehyde dehydrogenase
Length = 493
Score = 149 bits (377), Expect = 1e-35
Identities = 116/433 (26%), Positives = 206/433 (46%), Gaps = 23/433 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
PATG+ +G +S + + + A A + + +R Q+L I+EN++ + +
Sbjct: 40 PATGEIIGKVADVSVEETKKAISAANEAFKTYKNFTHVQRSQLLERWAELIMENKDDLVK 99
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYE 234
+ ++GK + A M E+ ++W + + ++ P++ + + ++ +
Sbjct: 100 MLTLENGKPLSQAEM-EVTTCSGYLKW---YAAEAVRTFGDVAPSSLQSQNFL-ISIK-Q 153
Query: 235 PLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGH 294
P+GV I WN+P + A++ G + + + + L QEA G
Sbjct: 154 PVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRTPYVCLGLVRLAQEA----GF 209
Query: 295 DPNLVQLCYCLPPTGNDDAAN--YFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVE 352
++ + T +D +A+ T++P+ + ++F GS V ++ +A ++ V +E
Sbjct: 210 PDGVLNVI-----TSSDASAHGKELTTNPIVRKVSFTGSTNVGKILMGQSASTIKKVSME 264
Query: 353 LGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVG 412
LGG FIV QA+ S F S GQ C+ RV V YD VS L ++V
Sbjct: 265 LGGNAPFIVFPDFPIDQAVESFCTI-KFNSCGQVCVCPNRVYVHKNVYDEFVSKLTEKVK 323
Query: 413 QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFF 472
+++G D+ V G +IS + ++ I DA+SKGAK+ GG + +G+FF
Sbjct: 324 TIKVGDGFDSSSAV--GPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISSS---KGYFF 378
Query: 473 QPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNR 532
+PT+L VT+DM ++ E FGP+ +V + DT++ I AN + GL G +F +
Sbjct: 379 EPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFTNNLSTMIH 438
Query: 533 VANSLTTGNVAIN 545
VA L G V N
Sbjct: 439 VAKELEVGLVGAN 451
>CE29393 [C] KOG2450 Aldehyde dehydrogenase
Length = 510
Score = 149 bits (376), Expect = 1e-35
Identities = 118/449 (26%), Positives = 202/449 (44%), Gaps = 27/449 (6%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLLSLKNFILENQEA 171
PA G+ L TD++ V A+ A +W + +R +L L + + ++
Sbjct: 52 PANGKVLAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRMDASQRGVLLNRLADLMERDRVI 111
Query: 172 IARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEV 231
+A + D+GK A ++ ++++ ++ ++ D P ++F
Sbjct: 112 LASLESLDNGKPYAVAYNADLPLSIKTLR-LLRRMADKNHGKTIPIEGDYF------TYT 164
Query: 232 RYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKA 291
R+EP+GV G I+ WN+P + ++ GN VV+K +EQ S+ L +EA
Sbjct: 165 RHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALTKEA--- 221
Query: 292 CGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LTPVV 350
G +V + +P G+ A +SH + F GS V V+KAAA+S + V
Sbjct: 222 -GFPDGVVNI---IPGYGHT-AGQAISSHMDVDKVAFTGSTEVGRLVMKAAAESNVKKVT 276
Query: 351 VELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDR 410
+ELGGK I+ DL G F + GQ C R V K YD V+ +
Sbjct: 277 LELGGKSPNIIFADA-DLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYDDFVARSKEL 335
Query: 411 VGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGH 470
+ +G D G + + + I+ GA+L+ GG+++ QGH
Sbjct: 336 AEKAVIGDPFDL--KTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAKHGD----QGH 389
Query: 471 FFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGEC 530
F +PT+ +V + M I+ E+FGP++T++R ++ + AN +GL + D +
Sbjct: 390 FVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGLAAGVMTKDIDKA 449
Query: 531 NRVANSLTTGNVAINDFATFYVCQLPFGG 559
+AN+ G+V +N + F PFGG
Sbjct: 450 LHIANATRAGSVWVNCYDVFDAA-APFGG 477
>7301524 [C] KOG2450 Aldehyde dehydrogenase
Length = 659
Score = 149 bits (376), Expect = 1e-35
Identities = 121/455 (26%), Positives = 201/455 (43%), Gaps = 35/455 (7%)
Query: 112 SYCPATGQFLGSFKSMSDTDIDEIVLLAERA---QLQWAKTSLKERLQVLLSLKNFILEN 168
++ PAT + + DID V A++A +W K S +R ++ L + +
Sbjct: 204 TFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRD 263
Query: 169 QEAIARVACRDSGKTMLDASMG---EILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKW 225
+ +A + +D+GK +A IL W + D + P F+
Sbjct: 264 KAFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDKFFGDTI-------PAGGFVSM 316
Query: 226 YKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLV 285
R EP+GVVG I+ WNYP L ++ G +++K +EQ ++ L
Sbjct: 317 -----TRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALA 371
Query: 286 QEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS 345
+EA G ++ + PT A ++HP + F GS + V++AAA S
Sbjct: 372 KEA----GFPAGVINVVNGFGPT----AGAAISAHPDIAKVAFTGSVEIGRIVMQAAATS 423
Query: 346 -LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALV 404
L V +ELGGK +V D D+ F + GQ+C R V K YD V
Sbjct: 424 NLKRVSLELGGKSPVVVFDDA-DIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFV 482
Query: 405 SILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHP 464
+ + ++G+ + ++V G I D+ ++ I +GAKL GG R +
Sbjct: 483 AKAAAKAKARKVGNPFE--QNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNV 540
Query: 465 NYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFG 524
G F +PT+ DV +DM+I+ E+FGP+ ++ + ++ I AN +GL +
Sbjct: 541 ----GFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVIT 596
Query: 525 ADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
D + + AN++ G+V IN + + PFGG
Sbjct: 597 NDINKALKFANNVDAGSVWINCYDA-VLPSTPFGG 630
>YBR006w [C] KOG2451 Aldehyde dehydrogenase
Length = 497
Score = 147 bits (370), Expect = 6e-35
Identities = 119/449 (26%), Positives = 199/449 (43%), Gaps = 26/449 (5%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
PA+G+ + + ++E + +A + T+ +ER + L ++ N +LEN + +A
Sbjct: 40 PASGEIIARVPEQPVSVVEEAIDVAYETFKTYKNTTPRERAKWLRNMYNLMLENLDDLAT 99
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARP-GPTNFFMKWYKGAEVRY 233
+ ++GK + +A GEI +W E + + +P P N + +R
Sbjct: 100 IITLENGKALGEAK-GEIKYAASYFEWYAEEAPRLYGATIQPLNPHN------RVFTIR- 151
Query: 234 EPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACG 293
+P+GV G I WN+P + A++ G VV+K Q S+ L ++A G
Sbjct: 152 QPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPKG 211
Query: 294 HDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVEL 353
N++ P G P K +TF GS V ++K ++ +L + EL
Sbjct: 212 SF-NVILSHANTPKLGKT-----LCESPKVKKVTFTGSTNVGKILMKQSSSTLKKLSFEL 265
Query: 354 GGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQ 413
GG FIV + QAL M F+ GQ C+ R+ V + D +L +RV +
Sbjct: 266 GGNAPFIVFEDADLDQALEQA-MACKFRGLGQTCVCANRLYVHSSIIDKFAKLLAERVKK 324
Query: 414 LRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNH--PNYPQGHF 471
+G +D G +I+ + ++E DA+ KGAK++ G R PN F
Sbjct: 325 FVIGHGLD--PKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPN-----F 377
Query: 472 FQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECN 531
+ P +L V +S E FGP+ + ++ + AN FGL +F +
Sbjct: 378 YAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTLY 437
Query: 532 RVANSLTTGNVAINDFATFYVCQLPFGGL 560
V+ +L TG V+ N F C +PFGG+
Sbjct: 438 TVSEALETGMVSCNT-GVFSDCSIPFGGV 465
>CE13415 [C] KOG2456 Aldehyde dehydrogenase
Length = 437
Score = 145 bits (367), Expect = 1e-34
Identities = 123/427 (28%), Positives = 198/427 (45%), Gaps = 26/427 (6%)
Query: 136 VLLAERAQLQWAKTSLKE-RLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILV 194
++ A+RA T E R + LL LK I EN+ A+ V +D + E+
Sbjct: 6 IVEAQRAYFNTGATKPAEFRKEQLLQLKKLIEENRAALTEVVWKDLRRRHEVTEPMELGG 65
Query: 195 TLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLG 254
+LE+I + +++ +D +KP+ PT + K V+ +P GVV I WNYP +L
Sbjct: 66 SLEEIAYYLKNLDDWMKPTYVE-PTVATLPTDKPYIVK-DPKGVVLVISPWNYPVSMVLL 123
Query: 255 PIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAA 314
P++ SI GN +V+K SE ++ F L+ + DP V + G +
Sbjct: 124 PMIPSIAAGNTIVIKPSELSENTAILFEKLIPKYF-----DPKYVTIVN----GGIPETT 174
Query: 315 NYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSI 374
F H+ + G PVA ++ AAA LTPV +ELGGK +V D D++ +
Sbjct: 175 ELLKER--FDHIIYTGCPPVAKIIMAAAAKHLTPVTLELGGKCPVVVEDDA-DIEISAQR 231
Query: 375 IMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISD 434
I RG + + GQ C+ + ++VS+ V+ + + + G+ E D +I+
Sbjct: 232 IARGKWLNCGQTCLAPDYILVSSATKPKFVAAIQKCLKEFYGGNA---KESKDYSRVINQ 288
Query: 435 NRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGP 494
F ++ L+ + SKG L N + + F P ++DV + H+E+FGP
Sbjct: 289 RHFDRISALLDE--SKGVVLAG-----NEESRDRSDRFIPPTVLDVEKTDPFMHDEIFGP 341
Query: 495 ILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFY-VC 553
+L ++ K+ + I N L IF D + R N T+G V +ND V
Sbjct: 342 VLPIITVKNLCESIDFINKGEKPLAAYIFTKDEAKVQRFLNETTSGGVTVNDVIMHVAVI 401
Query: 554 QLPFGGL 560
LPFGG+
Sbjct: 402 TLPFGGV 408
>CE06980 [C] KOG2450 Aldehyde dehydrogenase
Length = 506
Score = 144 bits (362), Expect = 5e-34
Identities = 118/477 (24%), Positives = 206/477 (42%), Gaps = 20/477 (4%)
Query: 109 MIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILEN 168
++ S P+TG+ + ++D+ V A+ A W KT++++R +L + N I E
Sbjct: 42 LMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKTWKKTTVQQRSALLNKVANLIEEF 101
Query: 169 QEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSA-RPGPTNFFMKWYK 227
+ IA + RD GK + A + +I ++ + L S PT F+ + K
Sbjct: 102 NDDIAILESRDQGKPIGLAKVMDIPRCVQNFRDFANAALYSLSTSTILEQPTGKFVNYVK 161
Query: 228 GAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQE 287
+P+GV G I WN P + L + ++ GN VV K SE + ++
Sbjct: 162 N-----DPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEM----TSVTAWVLMH 212
Query: 288 ALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLT 347
A K G P +V + A H ++F GS + + + A
Sbjct: 213 AFKLVGFPPGVVNMVI----GEGKSAGQRLVDHVDVPLISFTGSTVIGKKIQEDGAKLNK 268
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
V +E+GGK+ IV + + S I R +F + G+ C+ R+ V + V
Sbjct: 269 KVSLEMGGKNPGIVYSNYRKSDIAS--IARSSFLNQGEICLCTSRLFVQKPIFADFVKSY 326
Query: 408 NDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYP 467
+ + +G D V +GAM S + ++++ I A +GA +L GG
Sbjct: 327 VEEAKKFTVG---DPTTQVQIGAMNSKVHYEKVKSYIELAKKEGADILCGGVTTIQNGCE 383
Query: 468 QGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADF 527
G+F PT++V + + ++ +E+FGP++ + ++ I AN+ P+GL +++ +D
Sbjct: 384 NGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGLSATVWSSDS 443
Query: 528 GECNRVANSLTTGNVAINDFATFYVCQLPFGGLNXXXXXXXXXXXXXXXXCNAKSVC 584
E AN L G V N + + +PFGG +AK+VC
Sbjct: 444 DELLNTANELRAGTVWCNTWLARDL-SMPFGGCKQSGNGREGLHDSLHFYSDAKTVC 499
>CE02183 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 523
Score = 143 bits (361), Expect = 7e-34
Identities = 109/431 (25%), Positives = 194/431 (44%), Gaps = 20/431 (4%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
PAT + + + + ++ V A+ A W TS R Q + L+ I + + +A
Sbjct: 52 PATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLTRQQCMFKLQALIKRDMKKLAE 111
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYE 234
+ GKT+ DA G++ L+ ++EH V PS G T +
Sbjct: 112 SITIEQGKTLPDAE-GDVSRGLQ----VVEHACSV--PSLMMGETLPNVSRDMDTHSYRI 164
Query: 235 PLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGH 294
PLGV I +N+P L ++ TGN +V+K SEQ +++ L +EA G
Sbjct: 165 PLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEA----GV 220
Query: 295 DPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELG 354
V + + G A N+ +P K ++F+G H+ + A + V +G
Sbjct: 221 PDGCVNIIH-----GQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMG 275
Query: 355 GKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQL 414
K+ +++ Q L+ + F +AGQ C+ + ++ + L ++ ++ L
Sbjct: 276 AKNHGVIMADANKEQTLNQLTA-AAFGAAGQRCMALTTAVLVGEARAWLPELV-EKAKNL 333
Query: 415 RLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQP 474
++ + D D+G +IS ++ LI A +GA++ GS P + G+F P
Sbjct: 334 KVNAGWK--PDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNFVGP 391
Query: 475 TLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVA 534
T+L V +M E+FGP+L VM A++ ++ I + N P+G G +IF ++ +
Sbjct: 392 TILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATARKFT 451
Query: 535 NSLTTGNVAIN 545
N + G + IN
Sbjct: 452 NEVDVGQIGIN 462
>Hs4502033 [C] KOG2450 Aldehyde dehydrogenase
Length = 516
Score = 142 bits (357), Expect = 2e-33
Identities = 111/420 (26%), Positives = 193/420 (45%), Gaps = 34/420 (8%)
Query: 146 WAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIE- 204
W + ++L L + I ++ +A + D+GK + + + ++ + L+ +++
Sbjct: 92 WRRMDASHSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGW 151
Query: 205 ----HGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASI 260
HG+ + P +FF + R+EP+GV G I+ WN+P + ++
Sbjct: 152 ADKYHGKTI------PIDGDFF------SYTRHEPVGVCGQIIPWNFPLLMQAWKLGPAL 199
Query: 261 FTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSH 320
TGN VV+K +EQ ++ + L++EA G P +V + PT A SH
Sbjct: 200 ATGNVVVMKVAEQTPLTALYVANLIKEA----GFPPGVVNIVPGFGPT----AGAAIASH 251
Query: 321 PVFKHLTFIGSKPVAHHVLKAAADS-LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGT 379
+ F GS + + AA S L V +ELGGK I++ D+
Sbjct: 252 EDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDA-DMDWAVEQAHFAL 310
Query: 380 FQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQ 439
F + GQ C R V YD V R +G+ D+ + G + + +F +
Sbjct: 311 FFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDS--KTEQGPQVDETQFKK 368
Query: 440 LENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVM 499
+ I+ +GAKLL GG +G+F QPT+ DV + M I+ E+FGP++ ++
Sbjct: 369 ILGYINTGKQEGAKLLCGGGIAAD----RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQIL 424
Query: 500 RAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
+ K ++ + AN + +GL ++F D + N ++ +L G V +N + F Q PFGG
Sbjct: 425 KFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVF-GAQSPFGG 483
>CE27441 [C] KOG2456 Aldehyde dehydrogenase
Length = 493
Score = 141 bits (356), Expect = 3e-33
Identities = 114/411 (27%), Positives = 188/411 (45%), Gaps = 28/411 (6%)
Query: 151 LKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVL 210
+K R Q LL LK FI EN+EA++ +D + + EI +T+++I + +++ +D +
Sbjct: 22 VKFRKQQLLKLKKFIEENREALSEAVWKDLRRRHESTEILEIGMTIQEIDYFLKNIDDWV 81
Query: 211 KPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKC 270
KP+ F + +P GVV I WNYP +L P+V +I GN VV+K
Sbjct: 82 KPTH---VEKTFTTALDKPVIEKDPKGVVLIISPWNYPVSMILLPMVPAIAAGNTVVIKP 138
Query: 271 SEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIG 330
SE + F L+ P + Y G F H+ + G
Sbjct: 139 SELSENVAATFEKLI----------PKYFESKYVTVVNGGIPETTDLLKER-FDHILYTG 187
Query: 331 SKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGI 390
PVA ++ AAA LTPV +ELGGK +V D D+ + I G + + GQ C+
Sbjct: 188 CPPVAKIIMTAAAKHLTPVTLELGGKCPVVVEDDA-DIDISAKRIAWGKWLNCGQTCLAP 246
Query: 391 ERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSK 450
+ ++V++ LV+ + V + G D+ D MI+ F ++ L+ ++
Sbjct: 247 DYILVNSTVKPKLVAAIRKYVNEF-YGEDVK--ASKDYARMINQRHFDRISGLLDK--TQ 301
Query: 451 GAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRL 510
GA L+ GG R + + P ++DV + H+E+FGP+L ++ + + +
Sbjct: 302 GAVLI-GGER------DRADLYIPPTVLDVEKSDPFMHDEIFGPVLPIITVQSFSESLEY 354
Query: 511 ANAAPFGLGGSIFGADFGECNRVANSLTTGNVAIND-FATFYVCQLPFGGL 560
L IF + + R+ N ++G V +ND V LPFGG+
Sbjct: 355 IADGEKPLAAYIFTRNEAKVKRLLNETSSGGVTVNDVLMHITVDTLPFGGV 405
>At1g44170 [C] KOG2456 Aldehyde dehydrogenase
Length = 484
Score = 140 bits (353), Expect = 6e-33
Identities = 122/451 (27%), Positives = 209/451 (46%), Gaps = 43/451 (9%)
Query: 145 QWAKTSLKERLQVLLSLKNFILENQEAIARVACRDS-GKTMLDASMGEILVTLEKIQWII 203
+W T LK+ + I +N E A RD GK L++S+ E+ + I+ +
Sbjct: 32 EWRVTQLKKLM--------IICDNHEPEIVAALRDDLGKPELESSVYEVSLLRNSIKLAL 83
Query: 204 EHGEDVLKPS-ARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFT 262
+ ++ + P A+ T F AE+ EPLGVV I +WNYPF + P++ +I
Sbjct: 84 KQLKNWMAPEKAKTSLTTF----PASAEIVSEPLGVVLVISAWNYPFLLSIDPVIGAISA 139
Query: 263 GNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTS--- 319
GNAVV+K SE SS T L+++ L DP+ V++ + A TS
Sbjct: 140 GNAVVLKPSELAPASSALLTKLLEQYL-----DPSAVRVV---------EGAVTETSALL 185
Query: 320 HPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGT 379
+ + + GS + ++ AAA LTPVV+ELGGK +V+DS DL+ I+ G
Sbjct: 186 EQKWDKIFYTGSSKIGRVIMAAAAKHLTPVVLELGGKSP-VVVDSDTDLKVTVRRIIVGK 244
Query: 380 FQ-SAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFG 438
+ + GQ C+ + ++ + + L+ + +L + +E DM +++ N F
Sbjct: 245 WGCNNGQACVSPDYILTTKEYAPKLIDAMK---LELEKFYGKNPIESKDMSRIVNSNHFD 301
Query: 439 QLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTV 498
+L L+ D K+++GG + + PT+L+DV D I E+FGP+L +
Sbjct: 302 RLSKLL-DEKEVSDKIVYGGEKDR-----ENLKIAPTILLDVPLDSLIMSEEIFGPLLPI 355
Query: 499 MRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQ-LPF 557
+ + ++ + + P L +F + R A +++ G + +ND A LPF
Sbjct: 356 LTLNNLEESFDVIRSRPKPLAAYLFTHNKKLKERFAATVSAGGIVVNDIAVHLALHTLPF 415
Query: 558 GGLNXXXXXXXXXXXXXXXXCNAKSVCFDTL 588
GG+ + K+V + +L
Sbjct: 416 GGVGESGMGAYHGKFSFDAFSHKKAVLYRSL 446
>At2g14170 [EG] KOG2449 Methylmalonate semialdehyde dehydrogenase
Length = 607
Score = 139 bits (351), Expect = 1e-32
Identities = 115/440 (26%), Positives = 198/440 (44%), Gaps = 38/440 (8%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIAR 174
PAT + + ++ + V A++A W T + R +V+L + I +N + +A
Sbjct: 136 PATQEVVSKVPLTTNEEFKAAVSAAKQAFPLWRNTPITTRQRVMLKFQELIRKNMDKLAM 195
Query: 175 VACRDSGKTMLDASMGEILVTLEKIQWI-----IEHGEDVLKPSARPGPTNFFMKWYKGA 229
+ GKT+ D S G+I LE ++ ++ GE + P+ G + ++
Sbjct: 196 NITTEQGKTLKD-SHGDIFRGLEVVEHACGMATLQMGEYL--PNVSNGVDTYSIR----- 247
Query: 230 EVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEAL 289
EPLGV I +N+P L ++ GN ++K SE+ +S L EA
Sbjct: 248 ----EPLGVCAGICPFNFPAMIPLWMFPVAVTCGNTFILKPSEKDPGASVILAELAMEA- 302
Query: 290 KACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPV 349
G ++ + + G +D N + ++F+GS H+ AA +
Sbjct: 303 ---GLPDGVLNIVH-----GTNDTVNAICDDEDIRAVSFVGSNTAGMHIYARAAAKGKRI 354
Query: 350 VVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIV--SAKNYDALVSIL 407
+G K+ +VL L++++ G F +AGQ C+ + V+ AK+++ L
Sbjct: 355 QSNMGAKNHGLVLPDANIDATLNALLAAG-FGAAGQRCMALSTVVFVGDAKSWE---DKL 410
Query: 408 NDRVGQLRL--GSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
+R L++ GS+ D D+G +IS ++ LI + GAKLL G P
Sbjct: 411 VERAKALKVTCGSE----PDADLGPVISKQAKERICRLIQSGVDDGAKLLLDGRDIVVPG 466
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGA 525
Y +G+F PT+L VT DM+ E+FGP+L M+A D+ I + N +G G +IF +
Sbjct: 467 YEKGNFIGPTILSGVTPDMECYKEEIFGPVLVCMQANSFDEAISIINKNKYGNGAAIFTS 526
Query: 526 DFGECNRVANSLTTGNVAIN 545
+ + G + IN
Sbjct: 527 SGAAARKFQMDIEAGQIGIN 546
>At1g74920 [C] KOG2450 Aldehyde dehydrogenase
Length = 481
Score = 139 bits (350), Expect = 1e-32
Identities = 123/448 (27%), Positives = 200/448 (44%), Gaps = 55/448 (12%)
Query: 121 LGSFKSMSDTDIDEIVLLAERAQLQ-----WAKTSLKERLQVLLSLKNFILENQEAIARV 175
+G + + D+D V A RA + WAK R + L ++ + E + +A++
Sbjct: 42 IGDIPAATTEDVDVAVNAARRALSRNKGKDWAKAPGAVRAKYLRAIAAKVNERKTDLAKL 101
Query: 176 ACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLK--PSARPGPTNFFMKWYKGAEVRY 233
D GK + E + ++ + E D+ + + + P + M+ +K ++
Sbjct: 102 EALDCGKPL-----DEAVWDMDDVAGCFEFYADLAEGLDAKQKAPVSLPMESFKSYVLK- 155
Query: 234 EPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACG 293
+PLGVVG I WNYP + + S+ G ++K SE + L + + + G
Sbjct: 156 QPLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAILKPSEL----ASVTCLELADICREVG 211
Query: 294 HDPNLVQLCYCLPPTG-NDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVE 352
P ++ + TG +A SHP + F GS V+ AAA + PV +E
Sbjct: 212 LPPGVLNVL-----TGFGSEAGAPLASHPGVDKIAFTGSFATGSKVMTAAAQLVKPVSME 266
Query: 353 LGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVG 412
LGGK IV D V DL + + G F + GQ C R++V SI ++ +
Sbjct: 267 LGGKSPLIVFDDV-DLDKAAEWALFGCFWTNGQICSATSRLLVHE-------SIASEFIE 318
Query: 413 QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFF 472
+L S N++ ISD + +G +L S+ H +G F
Sbjct: 319 KLVKWS--KNIK-------------------ISDPMEEGCRLGPVVSKGQH--LEKGFFI 355
Query: 473 QPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNR 532
+PT++ DVT MQI EVFGP+L V D+ I LAN + +GLG ++ D C+R
Sbjct: 356 EPTIITDVTTSMQIWREEVFGPVLCVKTFASEDEAIELANDSHYGLGAAVISNDTERCDR 415
Query: 533 VANSLTTGNVAINDFATFYVCQLPFGGL 560
++ + G V IN + Q P+GG+
Sbjct: 416 ISEAFEAGIVWINCSQPCFT-QAPWGGV 442
>Hs4557303 [C] KOG2456 Aldehyde dehydrogenase
Length = 485
Score = 137 bits (345), Expect = 5e-32
Identities = 114/421 (27%), Positives = 195/421 (46%), Gaps = 29/421 (6%)
Query: 141 RAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQ 200
+A L L+ RLQ L +L+ + E ++ I D K+ + E++ L +I
Sbjct: 10 QAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEID 69
Query: 201 WIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASI 260
+++E+ + + +A+P N + A ++ +PLGVV I +WNYPF + P++ +I
Sbjct: 70 FMLENLPEWV--TAKPVKKNV-LTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAI 126
Query: 261 FTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSH 320
GNAV++K SE ++K L+ + L Q Y + G ++
Sbjct: 127 AAGNAVIIKPSELSENTAKILAKLLPQYLD---------QDLYIVINGGVEETTELLKQR 177
Query: 321 PVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTF 380
F H+ + G+ V V++AAA LTPV +ELGGK +D DL + I G +
Sbjct: 178 --FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSP-CYIDKDCDLDIVCRRITWGKY 234
Query: 381 QSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQL 440
+ GQ CI + ++ A + +V + + V + G +I E D +I+ F ++
Sbjct: 235 MNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-YGENIK--ESPDYERIINLRHFKRI 291
Query: 441 ENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMR 500
+L+ +G K+ GG Y PT+L DV ++ E+FGPIL ++
Sbjct: 292 LSLL-----EGQKIAFGGETDEATRY-----IAPTVLTDVDPKTKVMQEEIFGPILPIVP 341
Query: 501 AKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAIND-FATFYVCQLPFGG 559
K+ D+ I N L +F + R+ + ++G V ND F + PFGG
Sbjct: 342 VKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGG 401
Query: 560 L 560
+
Sbjct: 402 V 402
>Hs18603595 [C] KOG2456 Aldehyde dehydrogenase
Length = 508
Score = 137 bits (345), Expect = 5e-32
Identities = 114/421 (27%), Positives = 195/421 (46%), Gaps = 29/421 (6%)
Query: 141 RAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQ 200
+A L L+ RLQ L +L+ + E ++ I D K+ + E++ L +I
Sbjct: 10 QAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEID 69
Query: 201 WIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASI 260
+++E+ + + +A+P N + A ++ +PLGVV I +WNYPF + P++ +I
Sbjct: 70 FMLENLPEWV--TAKPVKKNV-LTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAI 126
Query: 261 FTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSH 320
GNAV++K SE ++K L+ + L Q Y + G ++
Sbjct: 127 AAGNAVIIKPSELSENTAKILAKLLPQYLD---------QDLYIVINGGVEETTELLKQR 177
Query: 321 PVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTF 380
F H+ + G+ V V++AAA LTPV +ELGGK +D DL + I G +
Sbjct: 178 --FDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSP-CYIDKDCDLDIVCRRITWGKY 234
Query: 381 QSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQL 440
+ GQ CI + ++ A + +V + + V + G +I E D +I+ F ++
Sbjct: 235 MNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-YGENIK--ESPDYERIINLRHFKRI 291
Query: 441 ENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMR 500
+L+ +G K+ GG Y PT+L DV ++ E+FGPIL ++
Sbjct: 292 LSLL-----EGQKIAFGGETDEATRY-----IAPTVLTDVDPKTKVMQEEIFGPILPIVP 341
Query: 501 AKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAIND-FATFYVCQLPFGG 559
K+ D+ I N L +F + R+ + ++G V ND F + PFGG
Sbjct: 342 VKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGG 401
Query: 560 L 560
+
Sbjct: 402 V 402
>Hs21359829 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 132 bits (331), Expect = 2e-30
Identities = 118/431 (27%), Positives = 189/431 (43%), Gaps = 31/431 (7%)
Query: 132 IDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGE 191
I E V A A L+ R+Q L +L+ I E ++ + D K +A E
Sbjct: 4 ISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEE 63
Query: 192 ILVTLEKIQWIIEH-GEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFH 250
++ LE+I+++I+ E P + Y + EPLGVV I +WNYPF+
Sbjct: 64 VVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELY----IHSEPLGVVLVIGTWNYPFN 119
Query: 251 NLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGN 310
+ P+V +I GNAVV+K SE + ++ + L D +L Y + G
Sbjct: 120 LTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYL-----DKDL----YPVINGGV 170
Query: 311 DDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQA 370
+ F H+ + GS V ++ AAA LTPV +ELGGK V D DL
Sbjct: 171 PETTELLKER--FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYV-DKNCDLDV 227
Query: 371 LSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGA 430
I G F ++GQ C+ + ++ + +V L + + G D + D G
Sbjct: 228 ACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAK--KSRDYGR 284
Query: 431 MISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNE 490
+IS F ++ LI +G K+ +GG+ Y PT+L DV + E
Sbjct: 285 IISARHFQRVMGLI-----EGQKVAYGGTGDAATRY-----IAPTILTDVDPQSPVMQEE 334
Query: 491 VFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATF 550
+FGP+L ++ + ++ I+ N L +F ++ ++ ++G VA ND
Sbjct: 335 IFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVH 394
Query: 551 YVC-QLPFGGL 560
LPFGG+
Sbjct: 395 ITLHSLPFGGV 405
>HsM4502035 [C] KOG2456 Aldehyde dehydrogenase
Length = 453
Score = 131 bits (329), Expect = 4e-30
Identities = 118/431 (27%), Positives = 188/431 (43%), Gaps = 31/431 (7%)
Query: 132 IDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGE 191
I E V A A L+ R Q L +L+ I E ++ + D K +A E
Sbjct: 4 ISEAVKRARAAFSSGRTRPLQFRFQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEE 63
Query: 192 ILVTLEKIQWIIEH-GEDVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFH 250
++ LE+I+++I+ E P + Y + EPLGVV I +WNYPF+
Sbjct: 64 VVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELY----IHSEPLGVVLVIGTWNYPFN 119
Query: 251 NLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGN 310
+ P+V +I GNAVV+K SE + ++ + L D +L Y + G
Sbjct: 120 LTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYL-----DKDL----YPVINGGV 170
Query: 311 DDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQA 370
+ F H+ + GS V ++ AAA LTPV +ELGGK V D DL
Sbjct: 171 PETTELLKER--FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYV-DKNCDLDV 227
Query: 371 LSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGA 430
I G F ++GQ C+ + ++ + +V L + + G D + D G
Sbjct: 228 ACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAK--KSRDYGR 284
Query: 431 MISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNE 490
+IS F ++ LI +G K+ +GG+ Y PT+L DV + E
Sbjct: 285 IISARHFQRVMGLI-----EGQKVAYGGTGDAATRY-----IAPTILTDVDPQSPVMQEE 334
Query: 491 VFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATF 550
+FGP+L ++ + ++ I+ N L +F ++ ++ ++G VA ND
Sbjct: 335 IFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVH 394
Query: 551 YVC-QLPFGGL 560
LPFGG+
Sbjct: 395 ITLHSLPFGGV 405
>CE05817 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 887
Score = 127 bits (318), Expect = 7e-29
Identities = 117/456 (25%), Positives = 193/456 (41%), Gaps = 57/456 (12%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERA--QLQWAKTSLKERLQVLLSLKNFILENQEAI 172
PAT + + + D+D V A++A + +W + S +ER + L L + E++E +
Sbjct: 450 PATEKPICELPLATVADVDRAVRAAKKAFERGEWRQMSARERGKRLYKLAELMEEHKEEL 509
Query: 173 ARVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWYK 227
A + D+G A + ++++ ++ G+ + +ARP
Sbjct: 510 ATLESLDAGAVYTLALKTHVGMSIDVWRYFAGWCDKIQGKTIPISNARPNKNLCL----- 564
Query: 228 GAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQE 287
EP+GVVG I WNYP L + A + +++ S +
Sbjct: 565 ---TLREPIGVVGLITPWNYPLMMLSWKMAACLAAAKIKLIEISGVI------------- 608
Query: 288 ALKACGHDPNLVQLCYCLPPTGNDD-AANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS- 345
N+V TG+ N T+HP + + F GS + V+++ A S
Sbjct: 609 ---------NIV--------TGSGSLVGNRLTAHPDVRKIGFTGSTEIGATVMESCAKSN 651
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
+ V +ELGGK I+ DL+ F + G+NCI RV ++ +D V
Sbjct: 652 IKKVSLELGGKSPLIIFADA-DLEKAVKQACGAVFFNKGENCIAAGRVFIAKSIHDDFVK 710
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
L + Q ++G +D G +L + A++ GAK+ GG R
Sbjct: 711 KLVEEAKQYQIGDPLD--RSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVEVGGKRLER-- 766
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTD--DCIRLANAAPFGLGGSIF 523
+G +F PT+L ++ ++ + E FGPI+ V D D D +R AN FGL +F
Sbjct: 767 --EGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRANDTEFGLAAGVF 824
Query: 524 GADFGECNRVANSLTTGNVAINDFATFYVCQLPFGG 559
D + RVA +L G V +N + V PFGG
Sbjct: 825 TRDSSKSLRVAEALHAGTVFVNTYQKTDVA-APFGG 859
>Hs4502043 [C] KOG2456 Aldehyde dehydrogenase
Length = 468
Score = 125 bits (315), Expect = 2e-28
Identities = 112/409 (27%), Positives = 179/409 (43%), Gaps = 31/409 (7%)
Query: 154 RLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPS 213
R L L F+ EN++ + +D K+ ++ + E+ ++ ++ + + +K
Sbjct: 26 RAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMKDE 85
Query: 214 ARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQ 273
P A +R EP G+V I WNYP + L P+V ++ GN VV+K SE
Sbjct: 86 RVP---KNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSE- 141
Query: 274 VVWSSKFFTLLVQEALKACGHDPNLV-QLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSK 332
SK ++ E L P V Q C+ + G + F ++ F GS
Sbjct: 142 ---ISKNVEKILAEVL------PQYVDQSCFAVVLGGPQETGQLLEHR--FDYIFFTGSP 190
Query: 333 PVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIER 392
V V+ AAA LTPV +ELGGK+ V D+ D Q +++ + + +AGQ C+ +
Sbjct: 191 RVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNC-DPQTVANRVAWFRYFNAGQTCVAPDY 249
Query: 393 VIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGA 452
V+ S + + L+ L + R D D ++G +I+ +F +L AL
Sbjct: 250 VLCSPEMQERLLPALQSTI--TRFYGD-DPQSSPNLGRIINQKQFQRLR-----ALLGCG 301
Query: 453 KLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLAN 512
++ GG Y PT+LVDV E + E+FGPIL ++ + D+ I N
Sbjct: 302 RVAIGGQSDESDRY-----IAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFIN 356
Query: 513 AAPFGLGGSIFGADFGECNRVANSLTTGNVAIND-FATFYVCQLPFGGL 560
L F RV ++G ND F + LPFGG+
Sbjct: 357 RREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGV 405
>Hs4557343 [C] KOG2453 Aldehyde dehydrogenase
Length = 511
Score = 120 bits (300), Expect = 8e-27
Identities = 100/430 (23%), Positives = 179/430 (41%), Gaps = 31/430 (7%)
Query: 109 MIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILEN 168
+I +YCPA + + + S D +E V A A WA +R +++ + + + E
Sbjct: 37 VITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREK 96
Query: 169 QEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDV---LKPSARPGPTNFFMKW 225
+ + + + GK +++ +GE+ ++ + + + + PS R G +W
Sbjct: 97 IQVLGSLVSLEMGKILVEG-VGEVQEYVDICDYAVGLSRMIGGPILPSERSGHA-LIEQW 154
Query: 226 YKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLV 285
P+G+VG I ++N+P VA NA+ + C +W T L+
Sbjct: 155 --------NPVGLVGIITAFNFP--------VAVYGWNNAIAMICGNVCLWKGAPTTSLI 198
Query: 286 QEALK---ACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAA 342
A+ A + N + C G D L+F GS V V
Sbjct: 199 SVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV 258
Query: 343 ADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDA 402
+ ++ELGG +A I + DL + + +AGQ C R+ + +D
Sbjct: 259 QERFGRSLLELGGNNAIIAFEDA-DLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDE 317
Query: 403 LVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYN 462
+V+ L Q+R+G+ D +V G + + + +A +G +++GG +
Sbjct: 318 VVNRLKKAYAQIRVGNPWD--PNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMD 375
Query: 463 HPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSI 522
P G++ +PT++ + D I+H E F PIL V + K+ ++ N GL SI
Sbjct: 376 RP----GNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSI 431
Query: 523 FGADFGECNR 532
F D G R
Sbjct: 432 FTKDLGRIFR 441
>7304212 [C] KOG2456 Aldehyde dehydrogenase
Length = 561
Score = 116 bits (290), Expect = 1e-25
Identities = 96/340 (28%), Positives = 148/340 (43%), Gaps = 27/340 (7%)
Query: 218 PTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWS 277
P F+ ++ +P GVV I +WNYP LL P+ ++I GN VV+K SE
Sbjct: 87 PPKSFVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANC 146
Query: 278 SKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHH 337
+KF ++ + L CY + G + A F ++ + GS V
Sbjct: 147 AKFIADVIPKYLD---------NDCYPVVCGGPSETAELLNQR--FDYIFYTGSTRVGKI 195
Query: 338 VLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSA 397
+ AA LTP +ELGGK + SV D++ I+ G + GQ CI + ++ S
Sbjct: 196 IHAAANKYLTPTTLELGGKSPCYIDKSV-DMRTAVKRILWGKLINCGQTCIAPDYILCSK 254
Query: 398 KNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHG 457
+ + + D + + G +I + D+ +I+ N F +L L+ K ++ G
Sbjct: 255 EVQEKFIVEAKDVLKEW-YGENIQS--SPDLSRVINANNFQRLLGLM-----KSGRVAVG 306
Query: 458 GSRYNHPNYPQGH-FFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPF 516
G NY F +PT+LVDV E I E+FGPIL + + D I+ NA
Sbjct: 307 G------NYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIKFINARES 360
Query: 517 GLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQLP 556
L IF N N +G + +ND Y + P
Sbjct: 361 PLVLYIFTPTAEVQNLFINGTQSGGLCVNDTIMHYAGKNP 400
>CE01232 [C] KOG2453 Aldehyde dehydrogenase
Length = 514
Score = 113 bits (282), Expect = 1e-24
Identities = 98/420 (23%), Positives = 184/420 (43%), Gaps = 27/420 (6%)
Query: 109 MIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILEN 168
++QS+ PA + + ++ + D + + A++A W + R +++ + + +
Sbjct: 38 VVQSFAPANNSPIANVQNGNVQDYEIAISEAKKAYNDWCEVPAPRRGEIVRQIGDKLRTQ 97
Query: 169 QEAIARVACRDSGKTMLDASMGEILVTLEKIQW---IIEHGEDVLKPSARPGPTNFFMKW 225
+ + ++ + GK + +GE+ ++ + + E + PS RPG +W
Sbjct: 98 LQNLGKLVSLEMGKISAEG-VGEVQEYVDICDYATGLSRSLEGKIFPSERPGHA-LLEQW 155
Query: 226 YKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLV 285
PLGVVG I ++N+P ++ TGN+VV K + ++ T LV
Sbjct: 156 --------NPLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLV 207
Query: 286 QEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS 345
+E L A +P L L G D ++F GS + V +
Sbjct: 208 EEVLVANNVNPALCSLV-----CGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQAR 262
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
+++ELGG +A IV + DL + + +AGQ C R+IV K YD ++
Sbjct: 263 FGKLLLELGGNNAIIVNEDA-DLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQVLE 321
Query: 406 ILNDRVGQL--RLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNH 463
L Q R+G +D+ + +G + + G+ + +++A++ G K+ +GG
Sbjct: 322 RLKKAYAQFESRIGCPLDS--NTIIGPLHNQQAVGKYKASVAEAVASGGKIEYGGKVLER 379
Query: 464 PNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIF 523
G+F PT++ + D + E F PIL V++ ++ I + N GL S+F
Sbjct: 380 ----DGNFVLPTIVTGLKHDSPVVLRETFAPILYVLKFSTLEEAIAINNEVDQGLSSSLF 435
>7293810 [C] KOG2453 Aldehyde dehydrogenase
Length = 594
Score = 111 bits (277), Expect = 4e-24
Identities = 99/427 (23%), Positives = 183/427 (42%), Gaps = 32/427 (7%)
Query: 110 IQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQ 169
+ SY P TGQ + + + +++ + LA A QW + R +++ + + + + +
Sbjct: 118 VTSYDPGTGQPIAKVRQGNVQELEHTIGLAVEAYKQWRQVPAPVRGEIVRQIGDELRKYK 177
Query: 170 EAIARVACRDSGKTMLDASMGEILVTLEKIQWI-----IEHGEDVLKPSARPGPTNFFMK 224
E + ++ + GK + GE+ ++ + I G+ + ++ +
Sbjct: 178 EPLGKLVSLEVGK-IYSEGQGEVQEFIDICDYAVGLSRIYSGQLI---NSERADHSILEA 233
Query: 225 WYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLL 284
W PLGVVG I ++N+P ++ TGN+V+ K + S T +
Sbjct: 234 W--------RPLGVVGVISAYNFPNAVFGWNAAIALTTGNSVLWKGAPSTPLVSVATTKI 285
Query: 285 VQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAAD 344
V E L+ + P +V LC G D + ++F GS V
Sbjct: 286 VAEVLRR-NNLPPVVTLCQ-----GGTDVGQTLVADKRVNLVSFTGSCQTGRDVGVEVQR 339
Query: 345 SLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALV 404
V++ELGG +A I+ +S AL + + G ++GQ C R+IV K +D V
Sbjct: 340 RFGKVILELGGNNALIIDESANVKMALDAALF-GCIGTSGQRCTTTRRIIVHEKLHDQFV 398
Query: 405 SILNDRVGQL--RLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYN 462
L + QL ++G ++ +G + + + I++A S G + GG+
Sbjct: 399 KELVGKYKQLISKIGHQLE--AQTLVGPVHTQQNVENYKAAIAEAKSLGGTVAFGGNVIQ 456
Query: 463 HPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSI 522
G + +PT++ + D + H E F PI+ +++AK+ D I N GL +I
Sbjct: 457 R----DGFYVEPTVITGLPHDASVVHRETFAPIVYILKAKNVDQAIEWNNEVEQGLSSAI 512
Query: 523 FGADFGE 529
F + G+
Sbjct: 513 FTENIGQ 519
>Hs4502045 [C] KOG2456 Aldehyde dehydrogenase
Length = 385
Score = 110 bits (276), Expect = 5e-24
Identities = 95/346 (27%), Positives = 156/346 (44%), Gaps = 27/346 (7%)
Query: 216 PGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVV 275
P TN FMK + EP G+V I WNYP + L +V ++ GN VV+K SE
Sbjct: 5 PRSTNLFMK-LDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQ 63
Query: 276 WSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVA 335
+ K ++ + L Q C+ + G H + ++ F GS V
Sbjct: 64 GTEKVLAEVLPQYLD---------QSCFAVV-LGGPQETGQLLEHKL-DYIFFTGSPRVG 112
Query: 336 HHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIV 395
V+ AA LTPV +ELGGK+ V D+ D Q +++ + + +AGQ C+ + V+
Sbjct: 113 KIVMTAATKHLTPVTLELGGKNPCYVDDNC-DPQTVANRVAWFCYFNAGQTCVAPDYVLC 171
Query: 396 SAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLL 455
S + + L+ L + R D D ++G +I+ +F +L L+ G +
Sbjct: 172 SPEMQERLLPALQSTI--TRFYGD-DPQSSPNLGRIINQKQFQRLRALL------GCGRV 222
Query: 456 HGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAP 515
G + N + + PT+LVDV E + E+FGPIL ++ + D+ I+ N
Sbjct: 223 AIGGQSNESD----RYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQE 278
Query: 516 FGLGGSIFGADFGECNRVANSLTTGNVAIND-FATFYVCQLPFGGL 560
L F N++ ++G+ N+ F + +PFGG+
Sbjct: 279 KPLALYAFSNSRQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGV 324
>At4g36250 [C] KOG2456 Aldehyde dehydrogenase
Length = 433
Score = 107 bits (267), Expect = 6e-23
Identities = 102/412 (24%), Positives = 166/412 (39%), Gaps = 72/412 (17%)
Query: 150 SLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDV 209
SLK R + ++ + +N++ I +D GK +A E+ V L I +
Sbjct: 26 SLKWRKAQIGAIYEMVKDNEDKICNALFQDLGKHSTEAFRDELGVVLRTATVAINCLDKW 85
Query: 210 LKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVK 269
P P F+ KG +V EP G V + SWN+P L P++ +I GN V++K
Sbjct: 86 AVPKHSKLPLLFYPA--KG-KVISEPYGTVLVLSSWNFPISLSLDPLIGAIAAGNTVLLK 142
Query: 270 CSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFI 329
SE +S F + L D +++ G D A H + + F
Sbjct: 143 SSELSPNASAFLAKTIPAYL-----DTKAIKVI-----EGGPDVATILLQHQ-WDKIFFT 191
Query: 330 GSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIG 389
GS + ++ AAA LTPV +ELGGK +CI
Sbjct: 192 GSPKIGRIIMAAAAQHLTPVTLELGGK-----------------------------SCIS 222
Query: 390 IERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALS 449
++ V++ L+ +L + G + E + + + + +L L+SD
Sbjct: 223 VDYVLIEKSFAPTLIDMLKPTIKSF-FGE--NPKESGCLSRIANKHHVQRLSRLLSDP-- 277
Query: 450 KGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIR 509
+PT+L+D D +I + E+FGPIL ++ +D + I
Sbjct: 278 -----------------------RPTILLDPPLDSEIMNEEIFGPILPIITVRDIQESIG 314
Query: 510 LANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFYVCQ-LPFGGL 560
+ N P L F D R+ + ++G+V ND Y+C LPFGG+
Sbjct: 315 IINTKPKPLAIYAFTNDENLKTRILSETSSGSVTFNDVMIQYMCDALPFGGV 366
>At1g54100 [C] KOG2453 Aldehyde dehydrogenase
Length = 508
Score = 106 bits (265), Expect = 9e-23
Identities = 92/418 (22%), Positives = 180/418 (43%), Gaps = 26/418 (6%)
Query: 109 MIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILEN 168
++ + PA Q + S D ++ + E A W + + +R ++ + + +
Sbjct: 35 LVSTLNPANNQPIAQVVEASLEDYEQGLKACEEAAKIWMQVTAPKRGDIVRQIGDALRSK 94
Query: 169 QEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDV---LKPSARPGPTNFFMKW 225
+ + R+ + GK + + +GE+ ++ + + + + PS RP M
Sbjct: 95 LDYLGRLLSLEMGKILAEG-IGEVQEVIDMCDFAVGLSRQLNGSVIPSERPNHMMLEM-- 151
Query: 226 YKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLV 285
+ PLG+VG I ++N+P L ++ GN VV K + + T LV
Sbjct: 152 -------WNPLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLV 204
Query: 286 QEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS 345
E L+ + P + C G + ++F GS V V +
Sbjct: 205 AEVLEK-NNLPGAIFTAMC----GGAEIGEAIAKDTRIPLVSFTGSSRVGSMVQQTVNAR 259
Query: 346 LTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVS 405
++EL G +A IV+D D+Q + ++ +AGQ C R+++ YD ++
Sbjct: 260 SGKTLLELSGNNAIIVMDDA-DIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLE 318
Query: 406 ILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPN 465
L Q+++G+ ++ + +G + + E I S+G K+L GG
Sbjct: 319 QLLTSYKQVKIGNPLE--KGTLLGPLHTPESKKNFEKGIEVIKSQGGKILTGGKAVEG-- 374
Query: 466 YPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIF 523
+G+F +PT+ ++++ D + E+F P+L V++ K + + + N+ P GL SIF
Sbjct: 375 --EGNFVEPTI-IEISADAAVVKEELFAPVLYVLKFKSFGEAVAINNSVPQGLSSSIF 429
>7298784 [F] KOG2452 Formyltetrahydrofolate dehydrogenase
Length = 816
Score = 105 bits (261), Expect = 3e-22
Identities = 91/348 (26%), Positives = 149/348 (42%), Gaps = 26/348 (7%)
Query: 115 PATGQFLGSFKSMSDTDIDEIVLLAERAQL-QWAKTSLKERLQVLLSLKNFILENQEAIA 173
P + L S TD+D+ V A A W + + ++R Q++L+L + + N+E +A
Sbjct: 451 PTNEEVLCKVACASATDVDKAVRAAHSAFYGSWRQITPRQRGQLMLNLADLMERNKEELA 510
Query: 174 RVACRDSGKTMLDASMGEILVTLEKIQWIIE-----HGEDVLKPSARPGPTNFFMKWYKG 228
+ DSG A + +++E ++ G + ARP F
Sbjct: 511 TIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTF------ 564
Query: 229 AEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEA 288
R EP+GV G I WNYP L + A I GN ++K ++ ++ F L A
Sbjct: 565 --TRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRA 622
Query: 289 LKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADS-LT 347
G P ++ + LP G+ DA H + + L F GS P+ H++K+ ADS L
Sbjct: 623 ----GFPPGVINV---LPGKGS-DAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLK 674
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
+ELGGK I+ D+ M F + G+NCI R+ V + +D + +
Sbjct: 675 KCSLELGGKSPLIIFADC-DMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRV 733
Query: 408 NDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLL 455
+ + +G +D G F +L + +GAKL+
Sbjct: 734 LKDLRTMTIGDPLD--RSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLV 779
>SPBC24C6.04 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 548
Score = 95.9 bits (237), Expect = 2e-19
Identities = 109/450 (24%), Positives = 193/450 (42%), Gaps = 47/450 (10%)
Query: 132 IDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFI-LENQEAIARVACRDSGKTMLDASMG 190
+++ + A R + W +R + L + I + + + GK + A +
Sbjct: 83 VEDAIEAALRGKKVWESLPFADRSAIFLKAAHLISTKYRYKLMAATMIGQGKNIWQAEID 142
Query: 191 EILVTLEKIQWIIEHGEDVLK---PSARPGPTNFFMKWYKGAEVRYEPL-GVVGAIVSWN 246
+ ++ +++ ++ ++ P PG N + Y PL G V AI +N
Sbjct: 143 AGMEIIDFLRFNTKYASELYASQPPENTPGVWN---------RMEYRPLEGFVYAITPFN 193
Query: 247 YPFHNLLGPIVAS-IFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCL 305
F + G + A+ + GN V++K S+ V SS +V + + G +Q
Sbjct: 194 --FTAIAGNLAAAPLLMGNVVLMKPSDHAVLSS----YIVYQIFREAGLPAGALQFI--- 244
Query: 306 PPTGNDDAANYFTSHPVFKHLTFIGSKPV--------AHHVLKAAADSLTPVVVELGGKD 357
P + + +HP F L F GS V +V + +V E GGK+
Sbjct: 245 -PGDAVEVSKVCFNHPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIVGETGGKN 303
Query: 358 AFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYD-ALVSILNDRVGQLRL 416
+V S + A+ + + R F+ GQ C + R+ VS ++ L +V L++
Sbjct: 304 FHLVHSSAEIKSAVVNAV-RAAFEYQGQKCSALSRLYVSKYAWENGFRDELTKQVKSLKV 362
Query: 417 GSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGA-KLLHGGSRYNHPNYPQGHFFQPT 475
G+ + + + +G +I F +L+ ++ A S ++L GG + +G F +PT
Sbjct: 363 GAPLTDFANF-VGPVIHQASFNKLKKVLESAASDSEIEVLAGGKADDS----EGFFVEPT 417
Query: 476 LLVDVTEDMQISHNEVFGPILTVMRAKDTD---DCIRLANAAPFGLGGSIFGADFGECNR 532
+L+ I NE+FGP+L+V +D + C + P+GL GSIF D +
Sbjct: 418 VLLSKNPKHDIFVNELFGPVLSVYVYEDDNLDAVCDLIDTTTPYGLTGSIFAQDRVVVRK 477
Query: 533 VANSL--TTGNVAINDFAT-FYVCQLPFGG 559
+ + L GN IND T V + PFGG
Sbjct: 478 LTDRLRNAAGNFYINDKCTGAVVGEQPFGG 507
>CE29047 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 89.7 bits (221), Expect = 1e-17
Identities = 116/482 (24%), Positives = 203/482 (42%), Gaps = 64/482 (13%)
Query: 105 EQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNF 164
EQ +I S +T L + + I E + +A +A+ W + LKER ++LL +
Sbjct: 78 EQKQVIPSDHRST---LAKYTYATGEQIQEAIDVALQARGAWERKPLKERAEILLRAADL 134
Query: 165 ILENQEAIARVACRDSGKTMLDAS----MGEILVTLEKIQWI---------IEHGEDVLK 211
A + + + TML EI E I + +EH E +
Sbjct: 135 ------AAGKYRMKLNASTMLGQGKNIIQAEIDAACELIDFFRFNAVFAMELEHYEPIST 188
Query: 212 PSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCS 271
+ ++G E G V AI +N+ P ++ GN + K S
Sbjct: 189 KITKN------TMQFRGME------GFVAAIAPFNFTAIGGNLPTAPALM-GNVSLWKPS 235
Query: 272 EQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGS 331
V S+ ++ E L+ G P ++ P+ + T+ P + F GS
Sbjct: 236 NTAVLSN----YIIYELLEEAGMPPGILSFL----PSDGPVFGDVITASPHLSAVNFTGS 287
Query: 332 KPVAHHVLKAAADSLTPVVV------ELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQ 385
P + + A++L V E GGK+ V S + A+++ R ++ +GQ
Sbjct: 288 VPTFKTIWRKVAENLDNYVTFPKLIGECGGKNFHFVHPSAH-VDAVAAGTARSAWEYSGQ 346
Query: 386 NCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLIS 445
C R+ + ++ ++ +++LG D V + A+I D F +L+ I
Sbjct: 347 KCSACSRMYAPKSIWPKILEKISAIHKEIKLGDVRDG--SVFLSAVIDDKAFARLKAYID 404
Query: 446 DALS--KGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKD 503
A + GA ++ GG + G+F +PTL+ ++ E+FGP++TV+ +D
Sbjct: 405 FAKTGADGANVVLGGKCDDKT----GYFIEPTLITVTDPKSKLLTEEMFGPVVTVLVYED 460
Query: 504 T--DDCI-RLANAAPFGLGGSIFGADFGECNRVANSL--TTGNVAINDFAT-FYVCQLPF 557
+ D+ + + +A P+GL G++F D R + L GN+ +ND +T V Q PF
Sbjct: 461 SKVDEVLATVKDATPYGLTGAVFSQDKEFLYRARDVLRDAVGNMYLNDKSTGSIVGQQPF 520
Query: 558 GG 559
GG
Sbjct: 521 GG 522
>YMR110c [C] KOG2456 Aldehyde dehydrogenase
Length = 532
Score = 88.2 bits (217), Expect = 3e-17
Identities = 93/417 (22%), Positives = 173/417 (41%), Gaps = 22/417 (5%)
Query: 148 KTSLKERLQVLLSLKNFILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGE 207
K L+ R L L + +++E + +D + +++ + E + I +IE
Sbjct: 43 KKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILP 102
Query: 208 DVLKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVV 267
++KP + FM + V G V I +N+P P+ A++ GN +V
Sbjct: 103 KLIKPRRVSDSSPPFM--FGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIV 160
Query: 268 VKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLT 327
+K SE ++ ++++ L G L+Q+ G D F +
Sbjct: 161 LKPSELTPHTA----VVMENLLTTAGFPDGLIQVVQ-----GAIDETTRLLDCGKFDLIF 211
Query: 328 FIGSKPVAHHVLKAAADSLTPVVVELGGKDAFIVLDSVK--DLQALSSIIMRGTFQSAGQ 385
+ GS V V + AA SLTP V+ELGGK + ++ K +++ I G F ++GQ
Sbjct: 212 YTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQ 271
Query: 386 NCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLIS 445
C+ + ++V Y ++ + + D E D MI + + + I+
Sbjct: 272 ICVSPDYLLVHKSIYPKVIKECESVLNEFYPSFD----EQTDFTRMIHEPAYKKAVASIN 327
Query: 446 DALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTD 505
+ G+K++ N + PT++ ++ D + E F P+L ++ +D D
Sbjct: 328 S--TNGSKIVPSKISIN-SDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLD 384
Query: 506 DCI-RLANAAPFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFY-VCQLPFGGL 560
+ I ++ L IF E NR+ L +G+ + D + PFGG+
Sbjct: 385 ETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGI 441
>Hs4502037 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 563
Score = 87.8 bits (216), Expect = 5e-17
Identities = 113/487 (23%), Positives = 200/487 (40%), Gaps = 56/487 (11%)
Query: 91 WKGKRMFPCSVYNPEQPHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLAERAQLQWAKTS 150
W + S +N H + +C A L ++ + A A+ +W
Sbjct: 74 WTSDVQYQVSPFN--HGHKVAKFCYADKSLL-----------NKAIEAALAARKEWDLKP 120
Query: 151 LKERLQVLLSLKNFILENQEA-IARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDV 209
+ +R Q+ L + + + A I GKT++ A + ++ ++ ++ ++
Sbjct: 121 IADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVEL 180
Query: 210 --LKPSARPGPTNFFMKWYKGAEVRYEPLGVVGAIVSWNYPF--HNLLGPIVASIFTGNA 265
+P + P TN + Y+G E G V AI +N+ NL G A GN
Sbjct: 181 EGQQPISVPPSTNSTV--YRGLE------GFVAAISPFNFTAIGGNLAG---APALMGNV 229
Query: 266 VVVKCSEQVVWSSKFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKH 325
V+ K S+ + +S V L+ G PN++Q P D TS
Sbjct: 230 VLWKPSDTAMLAS----YAVYRILREAGLPPNIIQFVPADGPLFGDTV----TSSEHLCG 281
Query: 326 LTFIGSKPVAHHVLKAAADSLTP------VVVELGGKDAFIVLDSVKDLQALSSIIMRGT 379
+ F GS P H+ K A +L + E GGK+ V S D++++ S +R
Sbjct: 282 INFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSA-DVESVVSGTLRSA 340
Query: 380 FQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQ 439
F+ GQ C R+ V + + L + ++++G ++ A+I F +
Sbjct: 341 FEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTF-FSAVIDAKSFAR 399
Query: 440 LENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVM 499
++ + A S + + G + + G+F +P ++ I E+FGP+L+V
Sbjct: 400 IKKWLEHARSSPSLTILAGGKCDDS---VGYFVEPCIVESKDPQEPIMKEEIFGPVLSVY 456
Query: 500 RAKDT--DDCIRLANA-APFGLGGSIFGAD---FGECNRVANSLTTGNVAINDFAT-FYV 552
D + ++L ++ +GL G++F D E +V + GN IND +T V
Sbjct: 457 VYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRN-AAGNFYINDKSTGSIV 515
Query: 553 CQLPFGG 559
Q PFGG
Sbjct: 516 GQQPFGG 522
>7296504 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 574
Score = 87.4 bits (215), Expect = 6e-17
Identities = 108/458 (23%), Positives = 198/458 (42%), Gaps = 44/458 (9%)
Query: 121 LGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFILENQEAIARVACRDS 180
L SF I++ + A Q +W + S+ +RL++ + + A
Sbjct: 100 LASFYYADKKLIEKAIKTAVETQPKWDRVSIADRLKIWEKAADLMATTYRQDLNAA---- 155
Query: 181 GKTMLDASMGEILVTLEKIQWIIEH---GEDVLKPSARPGPTNFFMKWYKGAEVRYEPL- 236
TML S I ++ +I+ LK + P + +K K + +RY +
Sbjct: 156 --TMLGQSKTAIQAEIDSAAELIDFIRMNAYFLKEVTKYQPISENIKVTKNS-LRYRGID 212
Query: 237 GVVGAIVSWNYPFHNLLGPIVA--SIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGH 294
G + A+ +N+ +G ++ GN V+ K S+ + S+ +++EA G
Sbjct: 213 GFIAAVSPFNF---TAIGGNLSYTPALMGNGVLWKPSDTAMLSNWIIFKIMREA----GV 265
Query: 295 DPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVV--- 351
+V P D T+ P + F GS P + + K +++ V
Sbjct: 266 PDGVVNFVPADGPVFGDT----ITASPHLAGINFTGSVPTFNRLWKQVGNNIDNYVNFPR 321
Query: 352 ---ELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILN 408
E GGK+ F + + D++++ + +R F+ GQ C R+ V + + L
Sbjct: 322 LTGECGGKN-FHFIHASADVESVVTSTIRSAFEYCGQKCSACSRMYVPESLWPQIKEGLV 380
Query: 409 DRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDAL-SKGAKLLHGGSRYNHPNYP 467
+L++G D+ + A+I D F ++ I A S ++L GG+ +
Sbjct: 381 CEAAKLKIG-DVQDFSSFT-SAVIDDKAFKRITGYIEHAKKSPNLEILAGGTYSDS---- 434
Query: 468 QGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTD--DCIRLAN-AAPFGLGGSIFG 524
+G+F PT+++ +I E+FGP+L++ K++D + ++L + + F L G++FG
Sbjct: 435 KGYFVNPTIVLSKDPKDRIMTEEIFGPVLSIYVYKESDLLETMKLVHTSTKFALTGAVFG 494
Query: 525 --ADFGECNRVANSLTTGNVAINDFAT-FYVCQLPFGG 559
DF +C + GN IND +T V Q PFGG
Sbjct: 495 QDEDFVKCALQEFKMAAGNFYINDKSTGSVVGQQPFGG 532
>Hs20481620 [C] KOG2456 Aldehyde dehydrogenase
Length = 292
Score = 83.6 bits (205), Expect = 9e-16
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 17/217 (7%)
Query: 229 AEVRYEPLGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEA 288
A +R EP G+V I WNYP + L P+V ++ GN VV+K SE SK ++ E
Sbjct: 61 AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSE----ISKNVEKILAEV 116
Query: 289 LKACGHDPNLV-QLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLT 347
L P V Q C+ + G + F ++ F GS V V+ AAA LT
Sbjct: 117 L------PQYVDQSCFAVVLGGPQETGQLLEHR--FDYIFFTGSPRVGKIVMTAAAKHLT 168
Query: 348 PVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSIL 407
PV +ELGGK+ V D+ D Q +++ + + +AGQ C+ + V+ S + + L+ L
Sbjct: 169 PVTLELGGKNPCYVDDNC-DPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPAL 227
Query: 408 NDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLI 444
+ R D D ++G +I+ +F +L L+
Sbjct: 228 QSTI--TRFYGD-DPQSSPNLGRIINQKQFQRLRALL 261
>YHR037w [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 575
Score = 78.6 bits (192), Expect = 3e-14
Identities = 117/468 (25%), Positives = 186/468 (39%), Gaps = 50/468 (10%)
Query: 119 QFLGSFKSMSDTDIDEIVLLAERAQLQWAKTSLKERLQVLLSLKNFI-LENQEAIARVAC 177
Q L + ++ D+ V A+ A+ W +R + L + I + + +
Sbjct: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM 148
Query: 178 RDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFMKWYKGAEVRYEPL- 236
GK + A + I + ++ +++ D+ A+ + W K Y PL
Sbjct: 149 LGQGKNVYQAEIDCITELSDFFRYYVKYASDLY---AQQPVESADGTWNKA---EYRPLE 202
Query: 237 GVVGAIVSWNYPF--HNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEA------ 288
G V A+ +N+ NL+G A GN VV K S+ S+ +++EA
Sbjct: 203 GFVYAVSPFNFTAIAANLIG---APALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGV 259
Query: 289 LKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTP 348
+ DP VQ+ + + A ++ S VFK L + V++
Sbjct: 260 INFIPGDP--VQVTDQVLADKDFGALHFTGSTNVFKSLY----GKIQSGVVEGKYRDYPR 313
Query: 349 VVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILN 408
++ E GGK+ +V S A+ S I RGTF+ GQ C R+ + + L+
Sbjct: 314 IIGETGGKNFHLVHPSANISHAVLSTI-RGTFEFQGQKCSAASRLYLPESKSE---EFLS 369
Query: 409 DRVGQLRLGSDID-----------NLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHG 457
D G L+ + + NL MG +I + F +L +I DA +
Sbjct: 370 DMFGILQSQNVVPMNTSASPISGGNLRGF-MGPVIHEQSFDKLVKVIEDAKKDPELEILY 428
Query: 458 GSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDT---DDCIRLANAA 514
G +Y+ QG F PT++ D E FGPILTV DT + C + N +
Sbjct: 429 GGQYDKS---QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTS 485
Query: 515 PFGLGGSIFGADFGECNRVANSL--TTGNVAINDFAT-FYVCQLPFGG 559
+ L G+IF D L + GN IND T V Q FGG
Sbjct: 486 QYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533
>At4g34240 [C] KOG2456 Aldehyde dehydrogenase
Length = 533
Score = 67.4 bits (163), Expect = 6e-11
Identities = 104/468 (22%), Positives = 190/468 (40%), Gaps = 65/468 (13%)
Query: 107 PHMIQSYCPATGQFLGSFKSMSDTDIDEIVLLAE--RAQLQWAKTSLKE-RLQVLLSLKN 163
P+ ++ C AT + + SD E LL + R+ +T E R+ L ++
Sbjct: 48 PYRLKFTCYATLSAVVK-EQASDFSGKEAALLVDELRSNFNSGRTKSYEWRISQLQNIAR 106
Query: 164 FILENQEAIARVACRDSGKTMLDASMGEILVTLEKIQWIIEHGEDVLKPSARPGPTNFFM 223
I E ++ I +D K L+A + E+ + ++ ++
Sbjct: 107 MIDEKEKCITEALYQDLSKPELEAFLAEVFYIISMSRFFTAFHLSTVESL---------- 156
Query: 224 KWYKGAEVRYEPLGVVGAI---VSWNYPFHNLLG--PIVASIFTGNAVVVKCSEQVVWSS 278
WY + +E ++ A V N+L P++ +I GNAVV+K SE +S
Sbjct: 157 -WYFSRFLDFEYKIILYACNQRVKELDGSRNVLSVEPVIGAIAAGNAVVLKPSEIAPAAS 215
Query: 279 KFFTLLVQEALKACGHDPNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHV 338
L E L D +++ P + F L+ + + H +
Sbjct: 216 SLLAKLFSEYL-----DNTTIRVIEGGVPE-TTALLDQKWDKIFFTDLSLL----LKHKI 265
Query: 339 LKAAADSLTPVVVELGGKDAFIVLDSVKDLQALSSIIMRGTFQ-SAGQNCIGIERVIVS- 396
+K + +L V+ L+ + I+ G + ++GQ CIG++ VI +
Sbjct: 266 VKFRSHTLIVVLW----------------LKVAARRIIAGKWACNSGQACIGVDYVITTK 309
Query: 397 ---AKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAK 453
+K DAL + L GQ + LE D+ +++ F +LE+++ + K
Sbjct: 310 DFASKLIDALKTELETFFGQ-------NALESKDLSRIVNSFHFKRLESMLKEN-GVANK 361
Query: 454 LLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANA 513
++HGG R PT+L+DV E + E+FGP+L ++ + +D ++ +
Sbjct: 362 IVHGG-RITEDKLK----ISPTILLDVPEASSMMQEEIFGPLLPIITVQKIEDGFQVIRS 416
Query: 514 APFGLGGSIFGADFGECNRVANSLTTGNVAINDFATFY-VCQLPFGGL 560
P L +F + + ++ G + IND V LPFGG+
Sbjct: 417 KPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGV 464
>Hs20546780 [C] KOG2450 Aldehyde dehydrogenase
Length = 637
Score = 61.6 bits (148), Expect = 4e-09
Identities = 66/313 (21%), Positives = 129/313 (41%), Gaps = 28/313 (8%)
Query: 236 LGVVGAIVSWNYPFHNLLGPIVASIFTGNAVVVKCSEQVVWSSKFFTLLVQEALKACGHD 295
+GV+G I+ + F ++ I ++ G VV +V + LL+ + G
Sbjct: 1 MGVIGLILPPTFSFLEMMWRICPALAVGCTVVA-----LVPPASPAPLLLAQLAGELGPF 55
Query: 296 PNLVQLCYCLPPTGNDDAANYFTSHPVFKHLTFIGSKPVAHHVLKAAADSLTPVVVELG- 354
P ++ + +G S P + + F G+ +A SL ELG
Sbjct: 56 PGILNVL-----SGPASLVPILASQPGIRKVAFCGAPEEG----RALRRSLAGECAELGL 106
Query: 355 --GKDAFIVLDSVKDLQALSSIIMRGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVG 412
G ++ ++L D+ + ++ + G + R+++ +D + L +R+G
Sbjct: 107 ALGTESLLLLTDTADVDSAVEGVVDAAWSDRGPGGL---RLLIQESVWDEAMRRLQERMG 163
Query: 413 QLRLGSDIDNLEDVDMGAMISDNRFGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFF 472
+LR G +D VDMGA ++ + +A S+GA++ G + + F+
Sbjct: 164 RLRSGRGLDGA--VDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGDVPS-----ERPFY 215
Query: 473 QPTLLVDVTEDMQISHNEVFGPILTVMRAKDTDDCIRLANAAPFGLGGSIFGADFGECNR 532
PTL+ ++ + EV P++ + + + +AN P G S++ G+
Sbjct: 216 PPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALE 275
Query: 533 VANSLTTGNVAIN 545
+ L G V IN
Sbjct: 276 LGYGLQVGTVWIN 288
>7294423 [E] KOG2455 Delta-1-pyrroline-5-carboxylate dehydrogenase
Length = 560
Score = 53.5 bits (127), Expect = 1e-06
Identities = 67/250 (26%), Positives = 111/250 (43%), Gaps = 23/250 (9%)
Query: 323 FKHLTFIGSKPVAHHVLKAAADSLTP------VVVELGGKDAFIVLDSVKDLQALSSIIM 376
F L S HV K +D + +V E G++ V S K ++++ S +
Sbjct: 279 FAGLNTQASAAFYRHVHKLVSDRMERYICFPRLVAECPGQNFHFVHASAK-VESVVSATV 337
Query: 377 RGTFQSAGQNCIGIERVIVSAKNYDALVSILNDRVGQLRLGSDIDNLEDVDMGAMISDNR 436
+ F AGQ + R+ V + + L L + QL +G I++ + D+GAM+ N
Sbjct: 338 QAAFGFAGQYANSLSRMYVPSSMWPRLREELVEATEQLTIGDPIES--ETDIGAMVHIND 395
Query: 437 FGQLENLISDALSKGAKLLHGGSRYNHPNYPQGHFFQPTLLVDVTEDMQ-ISHNEVFGPI 495
F +++ L+ +K + L GGS + G F PT +V V++ + + GP
Sbjct: 396 FRRMQKLLQ--RTKNMEQLCGGS----CDDSTGRFVDPT-IVRVSDPLDPLLCEPCCGPF 448
Query: 496 LTVMRAKDT--DDCIRL-ANAAPFGLGGSIFGADFGECNRVANSL--TTGNVAINDFATF 550
L V D + ++L AN + + L GSIF + N L + N+ +N+ T
Sbjct: 449 LPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLYVNERCTG 508
Query: 551 YVCQL-PFGG 559
L PFGG
Sbjct: 509 STYGLTPFGG 518
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,188,346
Number of Sequences: 60738
Number of extensions: 1582938
Number of successful extensions: 3772
Number of sequences better than 1.0e-05: 73
Number of HSP's better than 0.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3462
Number of HSP's gapped (non-prelim): 84
length of query: 640
length of database: 30,389,216
effective HSP length: 113
effective length of query: 527
effective length of database: 23,525,822
effective search space: 12398108194
effective search space used: 12398108194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)