ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2628 check: MH A KOG4150 RNA processing and modification Predicted ATP-dependent RNA helicase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2628 924258 921022 -1079
(1079 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR291w [A] KOG4150 Predicted ATP-dependent RNA helicase 1439 0.0
SPAC23A1.19c [A] KOG4150 Predicted ATP-dependent RNA helicase 350 7e-96
At5g08110 [A] KOG4150 Predicted ATP-dependent RNA helicase 238 5e-62
SPAC2G11.12 [L] KOG0351 ATP-dependent DNA helicase 71 8e-12
ECU07g1130 [L] KOG0351 ATP-dependent DNA helicase 71 8e-12
CE26682 [R] KOG0353 ATP-dependent DNA helicase 62 4e-09
Hs13787209 [A] KOG0331 ATP-dependent RNA helicase 62 6e-09
Hs14591902 [R] KOG0353 ATP-dependent DNA helicase 61 1e-08
SPBC13G1.10c [A] KOG0952 DNA/RNA helicase MER3/SLH1 DEAD-box sup... 57 2e-07
Hs18548973 [A] KOG0952 DNA/RNA helicase MER3/SLH1 DEAD-box super... 57 2e-07
At5g08620 [A] KOG0342 ATP-dependent RNA helicase pitchoune 57 2e-07
At5g08610 [A] KOG0342 ATP-dependent RNA helicase pitchoune 53 2e-06
YHR065c [A] KOG0330 ATP-dependent RNA helicase 53 3e-06
>YDR291w [A] KOG4150 Predicted ATP-dependent RNA helicase
Length = 1077
Score = 1439 bits (3724), Expect = 0.0
Identities = 715/1057 (67%), Positives = 844/1057 (79%), Gaps = 4/1057 (0%)
Query: 20 DEFWELKNIFFRLNTFYTFLLTRNHVITTFDVLKPAVQKAVKRPLLEQDFAKICVIMPSD 79
D F + FFRLNT YTFL+ R HV+ TF L ++ A+KR + ++D A + +MP +
Sbjct: 21 DAFRNFEQFFFRLNTLYTFLICRKHVVPTFKTLCGPIETALKRTVTKEDLAMVMALMPRE 80
Query: 80 TIFKYIDRNQFQVEEKVFNFKNGGYQQKDNDIFDLKAEDHQVNDEVEDSQVLVFQFKDGX 139
+FKYID NQ E K+F+F NGG+QQK+NDIF+LK D Q N + +Q+L+F+F DG
Sbjct: 81 CVFKYIDENQIYTETKIFDFNNGGFQQKENDIFELKDVDDQ-NQTQKSTQLLIFEFIDGT 139
Query: 140 XXXXXXXXXXXSDMNAPEFTTDAMKKMISRRKLSFESALNRFIFNCKLEGKTPMEELERL 199
S + P +TT+ MKKMIS+R+ F+S L FI + P EL L
Sbjct: 140 MQRSWSASDRFSQIKIPTYTTEEMKKMISKREALFKSRLREFILEKEKANLDPFSELTNL 199
Query: 200 SAARVPKKKDFMDPIESMLQAKKNI-ETEVVNEAGDSR-PTIPILLEKIKHSSIYNDQIT 257
+ +P+++D+ DPIE+M++AK+ E + N + +S TIP ++EK+K + Y QI
Sbjct: 200 AQKYIPRERDYEDPIEAMMKAKQESNEMSIPNYSNNSVITTIPQMIEKLKSTEFYASQIK 259
Query: 258 NSYIIPERIAKYGELEFALSPEVYQALEYKDFYSHQAAAINCIHKGENVIITTSTSSGKS 317
+ + IP R AKY L F L+PEVYQ +E+++FYSHQA AIN +H+GENVIITTSTSSGKS
Sbjct: 260 HCFTIPSRTAKYKGLCFELAPEVYQGMEHENFYSHQADAINSLHQGENVIITTSTSSGKS 319
Query: 318 LIYQLSAIDALLKDPHSTFMYIFPTKALAQDQKRSFQKLLSKIPELSHVIVDTYDGDTEQ 377
LIYQL+AID LLKDP STFMYIFPTKALAQDQKR+F+ +LSKIPEL + +VDTYDGDTE
Sbjct: 320 LIYQLAAIDLLLKDPESTFMYIFPTKALAQDQKRAFKVILSKIPELKNAVVDTYDGDTEP 379
Query: 378 QARAGIRISARVIFTNPDMIHTSILPNHPNWKMFLDNLRYVVVDELHIYKGFFGSHVALV 437
+ RA IR +ARVIFTNPDMIHTSILPNH NW+ FL +L+ VVVDELHIYKG FGSHVALV
Sbjct: 380 EERAYIRKNARVIFTNPDMIHTSILPNHANWRHFLYHLKLVVVDELHIYKGLFGSHVALV 439
Query: 438 MRRLVRIVKGFYKNEKLQFISCSATLKHPIQHMQDIFGIEQVTLINEDGSPRGTKHLVVW 497
MRRL+R+ FY+N LQFISCSATLK P+QHM+D+FGI +VTLI+EDGSP G KHLVVW
Sbjct: 440 MRRLLRLCHCFYENSGLQFISCSATLKSPVQHMKDMFGINEVTLIHEDGSPTGAKHLVVW 499
Query: 498 NPPKLSQHDRKRENFIGESAKILVQLIIQNVRTIAFCYVRRVCELLMKEVRIILQDMGKL 557
NPP L QH+RKRENFI ESAKILVQLI+ NVRTIAFCYVRRVCELLMKEVR I + G+
Sbjct: 500 NPPILPQHERKRENFIRESAKILVQLILNNVRTIAFCYVRRVCELLMKEVRNIFIETGRE 559
Query: 558 QLINEVMSYRGGYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSL 617
L+ EVMSYRGGYSASDRRKIE+EMFHGNL+AV+STNALELGIDIGGLD+VLMCGFPLS+
Sbjct: 560 DLVTEVMSYRGGYSASDRRKIEREMFHGNLKAVISTNALELGIDIGGLDAVLMCGFPLSM 619
Query: 618 ANFHQQSGRAGRRNRDSLTLVVASDSPVDQHYVAHSESLLEVDNPESYQDLVLDFDNMLM 677
ANFHQQSGRAGRRN DSLTLVVASDSPVDQHYVAH ESLLEV+N ESYQDLVLDF+N+L+
Sbjct: 620 ANFHQQSGRAGRRNNDSLTLVVASDSPVDQHYVAHPESLLEVNNFESYQDLVLDFNNILI 679
Query: 678 FESHIQCAAFELPIDIDRDSQYFDRKNLTTICETRLQHDANGYHANDRFLPWPSALISLR 737
E HIQCAAFELPI+ +RD QYF +L IC RL H+ +GYHA++RFLPWPS +SLR
Sbjct: 680 LEGHIQCAAFELPINFERDKQYFTESHLRKICVERLHHNQDGYHASNRFLPWPSKCVSLR 739
Query: 738 GSEEDIFAVVDITNGRNIIIEEVEASRTSFTLYDGGIFIHQGYPYLVKEFNPDDKYAKVQ 797
G EED FAVVDITNGRNIIIEE+EASRTSFTLYDGGIFIHQGYPYLVKEFNPD++YAKVQ
Sbjct: 740 GGEEDQFAVVDITNGRNIIIEEIEASRTSFTLYDGGIFIHQGYPYLVKEFNPDERYAKVQ 799
Query: 798 RVDVDWTTSQRDFTDVDPEEIEQIRSMQNSDVPAYYGKIRTTIIVFGFFKIDKQGRILDA 857
RVDVDW T+QRDFTDVDP+EIE IRS++NSDVP Y+GKI+TTIIVFGFFK+DK RI+DA
Sbjct: 800 RVDVDWVTNQRDFTDVDPQEIELIRSLRNSDVPVYFGKIKTTIIVFGFFKVDKYKRIIDA 859
Query: 858 VETHNPPVIINSKGLWIDIPKRALELIESKHLNSAGGIHAAQHAILGLLPRFIVAGVDEI 917
+ETHNPPVIINSKGLWID+PK ALE+ + K LN AG IH AQHAI+G+LPRFIVAGVDEI
Sbjct: 860 IETHNPPVIINSKGLWIDMPKYALEICQKKQLNVAGAIHGAQHAIMGMLPRFIVAGVDEI 919
Query: 918 STECKAPEKEFAERQTSRKRPARLVFYDSKGGKQGSGLCMKTFEHIEEILNGALQRVXXX 977
TECKAPEKEFAERQT RKRPARL+FYDSKGGK GSGLC+K FEHI++I+ +L+R+
Sbjct: 920 QTECKAPEKEFAERQTKRKRPARLIFYDSKGGKYGSGLCVKAFEHIDDIIESSLRRIEEC 979
Query: 978 XXXXXXXXXVAAAFCKENSLVLSKPAALVILHCILGHKESSFMTRIKDGPEPNMPEILVE 1037
VAA+FCKENSLVLSKP A V+LHCILGH E SF+ IKDGPEPNMPEI VE
Sbjct: 980 PCSDGCPDCVAASFCKENSLVLSKPGAQVVLHCILGHSEDSFIDLIKDGPEPNMPEIKVE 1039
Query: 1038 TIEPVSGHVKFSKDLQVIDTRE-IKNGEENLVTIKKE 1073
T+ PVS HV FS D ++ID R K+ IKKE
Sbjct: 1040 TVIPVSEHVNFSDDFKIIDVRRATKDDTHTNEIIKKE 1076
>SPAC23A1.19c [A] KOG4150 Predicted ATP-dependent RNA helicase
Length = 452
Score = 350 bits (898), Expect = 7e-96
Identities = 167/385 (43%), Positives = 255/385 (65%), Gaps = 6/385 (1%)
Query: 590 VVSTNALELGIDIGGLDSVLMCGFPLSLANFHQQSGRAGRRNRDSLTLVVASDSPVDQHY 649
+++TNALELGIDIG LD+V+ GFP SL+N QQ GRAGRRN+ SL + + PVDQ Y
Sbjct: 3 IIATNALELGIDIGSLDAVITIGFPYSLSNLRQQFGRAGRRNKSSLAVYIVETFPVDQFY 62
Query: 650 VAHSESLLEVDNPESYQDLVLDFDNMLMFESHIQCAAFELPIDIDRDSQYFDRKNLTTIC 709
+ H + N E L LD N ++ SH+QCAA+ELPI+I D ++F + + IC
Sbjct: 63 LKHPILIHTQPNAE----LTLDLTNEVLLASHLQCAAYELPINIRSDEKFFGNQ-IQDIC 117
Query: 710 ETRLQHDANGYHANDRFLPWPSALISLRGSEEDIFAVVDITNGRNIIIEEVEASRTSFTL 769
E L+ Y + ++LP+P++ + +R ED+F +VD+TN +N+I+E +E R + T
Sbjct: 118 EANLEMVEESYRPHPKYLPFPASQVRIRSVSEDMFTLVDVTNDKNVILELLEPFRVALTA 177
Query: 770 YDGGIFIHQGYPYLVKEFNPDDKYAKVQRVDVDWTTSQRDFTDVDPEEIEQIRSMQNSDV 829
Y+G ++++QG ++++ N + + +VDV+W+T QRDFTDVDP ++M S
Sbjct: 178 YEGAVYVYQGKTFIIRLLNINKRIITAHQVDVEWSTLQRDFTDVDPVRSLMKKTMHGS-T 236
Query: 830 PAYYGKIRTTIIVFGFFKIDKQGRILDAVETHNPPVIINSKGLWIDIPKRALELIESKHL 889
Y+G ++ T+ VFG+FK++KQ ILD V+ + PV I+S+G WID+P +E++ K +
Sbjct: 237 NIYFGAVKATLHVFGYFKVNKQKDILDVVDITDHPVEIDSRGFWIDVPWHIIEVLSLKKI 296
Query: 890 NSAGGIHAAQHAILGLLPRFIVAGVDEISTECKAPEKEFAERQTSRKRPARLVFYDSKGG 949
N A IHAAQHA+L L+P FI ++I TECKA EKE+ E ++ R+RP+RL+FYD+ G
Sbjct: 297 NGAASIHAAQHALLSLMPIFISNSGNDIRTECKAGEKEYKEAKSERRRPSRLIFYDNCGD 356
Query: 950 KQGSGLCMKTFEHIEEILNGALQRV 974
G+GLC K +EH +E++ A++R+
Sbjct: 357 SSGAGLCNKAYEHTDELITMAIERI 381
>At5g08110 [A] KOG4150 Predicted ATP-dependent RNA helicase
Length = 1058
Score = 238 bits (606), Expect = 5e-62
Identities = 169/575 (29%), Positives = 282/575 (48%), Gaps = 55/575 (9%)
Query: 472 DIFGIEQVTLINEDGSPRGTKHLVVWNP--PKLSQHDRKRENF----------------- 512
++ + ++ L+ DGSP K V+WNP P S+ ++ +
Sbjct: 493 ELANLSELELVTIDGSPSSEKLFVLWNPSAPPTSKSEKSSKVVSSSEAAADKPSGAAVDT 552
Query: 513 ----IGESAKILVQLIIQNVRTIAFCYVRRVCELLMKEVRIILQDMGKLQLINEVMSYRG 568
E + + +++ +R IAFC R++CEL++ R IL + L+ + SYRG
Sbjct: 553 LSGPASEVSHLFAEMVQHGLRCIAFCPSRKLCELVLCLTREILAETAP-HLVEAITSYRG 611
Query: 569 GYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSLANFHQQSGRAG 628
GY A DRRKIE ++F G L + +TNALELGID+G +D L GFP S+A+ QQ+GR+G
Sbjct: 612 GYIAEDRRKIESDLFGGKLCGIAATNALELGIDVGHIDVTLHLGFPGSIASLWQQAGRSG 671
Query: 629 RRNRDSLTLVVASDSPVDQHYVAHSESLLEVDNPESYQDLVLDFDNMLMFESHIQCAAFE 688
RR + SL + VA P+DQ+Y++ + L + +D N + H+ CAA E
Sbjct: 672 RRQKPSLAVYVAFLGPLDQYYMSFPDKLF----GSPIECCHIDSQNKHVLMQHLACAALE 727
Query: 689 LPIDIDRDSQYFDRKNLTTICETR----LQHDANGYHANDRFLPW------PSALISLRG 738
P+ + D Q+F + E R L D + ++ R + P+ ++S+R
Sbjct: 728 HPLSLQYDQQHFGSGLSDPLAELRNKGFLSFDPS-RDSSSRIWNYIGREKNPARIVSIRA 786
Query: 739 SEEDIFAVVDITNGRNIIIEEVEASRTSFTLYDGGIFIHQGYPYLVKEFNPDDKYAKVQR 798
E + V++ +++E+E S+ F +Y+G I+++QG YLV + +K A +
Sbjct: 787 IETVRYRVME--KKSKDVLDEIEESKAFFHVYEGAIYMNQGRNYLVTSLDIKEKVALCEL 844
Query: 799 VDVDWTTSQRDFTDVDPEEIEQIRSMQNSDVPA-YYGKIRTTIIVFGFFKIDKQ-GRILD 856
V+VD+ T RD+TD+ + ++ P R T FGF +I ++ ++D
Sbjct: 845 VNVDYYTRTRDYTDIKVTGGDTAYPVKAPKKPTPQTHACRVTTKWFGFLRIRRRNNEVID 904
Query: 857 AVETHNPPVIINSKGLWIDIPKRALELIESKHLNSAGGIHAAQHAILGLLPRFIVAGVDE 916
VE P S+ +WI +P +E+ +L G+HAA HA++ ++P + +
Sbjct: 905 DVELSLPSYTYQSQAVWIQVPMSVKLAVETANLPFRAGLHAACHALVNVVPTRVTCNYSD 964
Query: 917 ISTECKAPEKEFAERQTSRKRPARLVFYDSKGGKQGSGLCMKTFEHIEEILNGA--LQRV 974
I+ EC P+++ R PAR++ YD G G+G+ K E+L A L R
Sbjct: 965 IAPECPNPQEQ-------RYFPARILVYDRHPG--GTGISAKICPLFFELLKDARDLLRS 1015
Query: 975 XXXXXXXXXXXXVAAAF-CKENSLVLSKPAALVIL 1008
A F C+ + +L K AA++I+
Sbjct: 1016 CEKCPPETGCPKCAQTFGCRGYNELLHKKAAIMIM 1050
Score = 94.0 bits (232), Expect = 1e-18
Identities = 57/169 (33%), Positives = 88/169 (51%), Gaps = 5/169 (2%)
Query: 242 LLEKIKHSSIYNDQITNSYIIPERIAKYGELEFALSPEVYQALE---YKDFYSHQAAAIN 298
++E +++ Q+ + +I R + Y E+ LS AL+ YSHQA AI+
Sbjct: 344 MVEHLRNGIGSKGQVVHVEVIKARKSAYVEMSDKLSETTKSALKRIGLNTLYSHQAEAIS 403
Query: 299 CIHKGENVIITTSTSSGKSLIYQLSAIDALLKDPHSTFMYIFPTKALAQDQKRSFQKLLS 358
G+NV + T TSSGKSL Y + + L KD +S +Y+FPTKALAQDQ R+ L+
Sbjct: 404 AALAGKNVAVATMTSSGKSLCYNVPVFEELCKDTNSCALYLFPTKALAQDQLRALSDLIK 463
Query: 359 KIPELSHVIVDTYDGDTEQQARAGIRISARVIFTNPDMIHTSILPNHPN 407
+ + + YDGDT + R +R +AR+ N + + P+
Sbjct: 464 GFE--ASINMGVYDGDTPYKDRTRLRSNARLELANLSELELVTIDGSPS 510
>SPAC2G11.12 [L] KOG0351 ATP-dependent DNA helicase
Length = 1328
Score = 71.2 bits (173), Expect = 8e-12
Identities = 90/370 (24%), Positives = 161/370 (43%), Gaps = 44/370 (11%)
Query: 272 LEFALSPEVYQALEYK----DFYSHQAAAINCIHKGENVIITTSTSSGKSLIYQLSAIDA 327
L + S EV L++K F +Q AIN G++V I T GKSL YQL A+
Sbjct: 499 LSYPWSKEVLGCLKHKFHLKGFRKNQLEAINGTLSGKDVFILMPTGGGKSLCYQLPAVIE 558
Query: 328 LLKDPHSTFMYIFPTKALAQDQKRSFQKLLSKIPELSHVIVDTYDGDTEQQARAGI---R 384
T + I P +L QDQ +KL IP L + D +Q + +
Sbjct: 559 GGASRGVTLV-ISPLLSLMQDQLDHLRKL--NIPSLP--LSGEQPADERRQVISFLMAKN 613
Query: 385 ISARVIFTNPDMIH-----TSILPNHPNWKMFLDNLRYVVVDELHIYKGFFGSHVALVMR 439
+ ++++ P+ + T +L + K+ L +V+DE H + H
Sbjct: 614 VLVKLLYVTPEGLASNGAITRVLKSLYERKL----LARIVIDEAHCVSHW--GHDFRPDY 667
Query: 440 RLVRIVKGFYKNEKLQFISCSATLKHPIQHMQDIFGIEQVTLINEDGSPRGTKHLVVWNP 499
+ + +++ Y+ + F++ +AT ++ +DI ++ E S +N
Sbjct: 668 KQLGLLRDRYQG--IPFMALTATANEIVK--KDIINTLRMENCLELKSS--------FNR 715
Query: 500 PKLSQHDRKRENFIGESAKILVQLIIQNVRTIAFCYVRRVCELLMKEVRIILQDMGKLQL 559
P L + +++ E + + + I +C R CE + ++R D G
Sbjct: 716 PNLFYEIKPKKDLYTELYRFISNGHLHE-SGIIYCLSRTSCEQVAAKLR---NDYGL--- 768
Query: 560 INEVMSYRGGYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSLAN 619
+ Y G +R++I+ E G+ + +V+T A +G+D G + V+ FP SL
Sbjct: 769 --KAWHYHAGLEKVERQRIQNEWQSGSYKIIVATIAFGMGVDKGDVRFVIHHSFPKSLEG 826
Query: 620 FHQQSGRAGR 629
++Q++GRAGR
Sbjct: 827 YYQETGRAGR 836
>ECU07g1130 [L] KOG0351 ATP-dependent DNA helicase
Length = 766
Score = 71.2 bits (173), Expect = 8e-12
Identities = 79/360 (21%), Positives = 159/360 (43%), Gaps = 35/360 (9%)
Query: 282 QALEYKDFYSHQAAAINCIHKGENVIITTSTSSGKSLIYQLSAIDALLKDPHSTFMYIFP 341
+ + K+F ++Q I G++V + T GKS+ YQL A L+ D + + P
Sbjct: 231 EVFKMKEFRTNQREVIQACLSGKDVFVLMPTGGGKSICYQLPA---LVYD--GITIVVSP 285
Query: 342 TKALAQDQKRSF-QKLLSKIPELSHVIVDTYDGDTEQQARAGIRISARVIFTNPDMIHTS 400
+L QDQ R+ QK + +P S++ + D Q G + ++ + P++I S
Sbjct: 286 LLSLVQDQIRNLLQKGILALPINSNL--SRAERDLVFQVLGGDELICKIFYVTPELIAKS 343
Query: 401 -ILPNHPNWKMFLDNLRYVVVDELHIYKGFFGSHVALVMRRLVRIVKGFYKNEKLQFISC 459
+ + + L+ V+DE H + H + + ++ Y + + ++
Sbjct: 344 GHFHDVLSGLVCRGRLKRFVIDEAHCVSQW--GHDFRPDYKELGSMRARYPSVPIIALTA 401
Query: 460 SATLKHPIQHMQDIFGIEQVTLINEDGSPRGTKHLVV-WNPPKLSQHDRKRENFIGESAK 518
+AT K + ++++ GI RG + + +N L R + + +
Sbjct: 402 TATQKVEMDILENL-GI------------RGCETFKMSFNRSNLRYEVRAKTSTVELDIA 448
Query: 519 ILVQLIIQNVRTIAFCYVRRVCELLMKEVRIILQDMGKLQLINEVMSYRGGYSASDRRKI 578
VQ + I +C ++ CE++ ++ +GK Y G S ++R +
Sbjct: 449 SFVQTHFPDCCGIIYCTSKKECEMISEK-------LGKYM---GTAFYHAGLSKNERNSV 498
Query: 579 EQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSLANFHQQSGRAGRRNRDSLTLV 638
+++ G + +V+T A +GID + V+ P SL ++Q++GRAGR +S+ ++
Sbjct: 499 QEKWNRGEFKVIVATIAFGMGIDKKDVRFVIHYCIPKSLEGYYQETGRAGRDGLESVCVL 558
>CE26682 [R] KOG0353 ATP-dependent DNA helicase
Length = 674
Score = 62.4 bits (150), Expect = 4e-09
Identities = 72/335 (21%), Positives = 132/335 (38%), Gaps = 27/335 (8%)
Query: 293 QAAAINCIHKGENVIITTSTSSGKSLIYQLSAIDALLKDPHSTFMYIFPTKALAQDQKRS 352
Q AAIN + E+ ++ ST GKSL YQL A+ A + + + P +L +DQ
Sbjct: 114 QRAAINAVMSKEDAVVILSTGGGKSLCYQLPALLA-----NGLALVVSPLISLVEDQILQ 168
Query: 353 FQKLLSKIPELSHVIVDTYDGDTEQQARAGIRISARVIFTNPDMIHTS-ILPNHPNWKMF 411
+ L L + + + A R+++ P+ + S + N +
Sbjct: 169 LRSLGIDSSSL-NANTSKEEAKRVEDAITNKDSKFRLLYVTPEKLAKSKKMMNKLEKSLS 227
Query: 412 LDNLRYVVVDELHIYKGFFGSHVALVMRRLVRIVKGFYKNEKLQFISCSATLKHPIQHMQ 471
+ L+ + +DE+H + H + ++K +K + ++ +AT + + ++
Sbjct: 228 VGFLKLIAIDEVHCCSQW--GHDFRTDYSFLNVLKRQFKGVPILGLTATAT-SNVLDDVK 284
Query: 472 DIFGIEQVTLINEDGSPRGTKHLVVWNPPKLSQHDRKRENFIGESAKILVQLIIQNVRTI 531
D+ GI+ + K+ VV P E+ E ++ I
Sbjct: 285 DMLGIQAALTFRAGFNRSNLKYKVVQKPGS--------EDECTEEIAKTIKRDFAGQTGI 336
Query: 532 AFCYVRRVCELLMKEVRIILQDMGKLQLINEVMSYRGGYSASDRRKIEQEMFHGNLRAVV 591
+C R CE + K L+ G + Y DR Q G ++ +V
Sbjct: 337 IYCLSRNDCEKVAK----ALKSHG-----IKAKHYHAYMEPVDRSGAHQGWISGKIQVIV 387
Query: 592 STNALELGIDIGGLDSVLMCGFPLSLANFHQQSGR 626
+T A +GID + V+ P S+ N++Q S R
Sbjct: 388 ATVAFGMGIDKPNVRFVIHHSLPKSIENYYQASAR 422
>Hs13787209 [A] KOG0331 ATP-dependent RNA helicase
Length = 715
Score = 61.6 bits (148), Expect = 6e-09
Identities = 110/514 (21%), Positives = 205/514 (39%), Gaps = 73/514 (14%)
Query: 153 MNAPEFTTDAMKKMISRRKLSFESALNRFIFNCKLEGKTPMEELERLSAARVPKKKDFMD 212
MN+P+ K+ S+ +S ++ R + K P+E+ ++ +++ K +
Sbjct: 1 MNSPKSKKAKKKEEPSQNDISPKTKSLR-------KKKEPIEK--KVVSSKTKKVTKNEE 51
Query: 213 PIESMLQAKKNIETEVVNEA-GDSRPTIPILLEKIKH-----------SSIYNDQITNSY 260
P E + A K + + E G++R P L H S N +I
Sbjct: 52 PSEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQEI 111
Query: 261 IIPERIAKYGELEFALSPEVYQALEYKD---FYSHQAAAINCIHKGENVIITTSTSSGKS 317
+ ++ + F +S E + L+ + + QA + ++ G+++I T +GK+
Sbjct: 112 PVEQKEGAFSN--FPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKT 169
Query: 318 LIYQLSAIDAL---LKDPHS----TFMYIFPTKALAQDQKRSFQKLLSKIPELSHVIVDT 370
+ + I+ L L+D + + PT+ LA + F + K+
Sbjct: 170 FSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACFYGGTP 229
Query: 371 YDGDTEQQARAGIRISARVIFTNPDMIHTSILPNHPNWKMFLDNLRYVVVDELH--IYKG 428
Y G E+ R GI I + P I I N K+ L L++VV+DE+ + G
Sbjct: 230 YGGQFERM-RNGIDI----LVGTPGRIKDHI----QNGKLDLTKLKHVVLDEVDQMLDMG 280
Query: 429 FFGSHVALVMRRLVRIVKGFYKNEKLQFISCSATLKHPI-----QHMQDIFGIEQVTLIN 483
F A + ++ + + Q + SAT H + ++M+ + EQV LI
Sbjct: 281 F-----ADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTY--EQVDLIG 333
Query: 484 EDGSPRGTKHLVVWNPPKLSQHDRKRENFIGESAKILVQLIIQNVRTIAFCYVRRVCELL 543
+ + K + + H +R IG+ ++ RTI FC +
Sbjct: 334 K----KTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSG---HQGRTIIFCETK------ 380
Query: 544 MKEVRIILQDMGKLQLINEVMSYRGGYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIG 603
KE + + Q+ Q + S G R + +G+ +V+TN G+DI
Sbjct: 381 -KEAQELSQNSAIKQ---DAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIP 436
Query: 604 GLDSVLMCGFPLSLANFHQQSGRAGRRNRDSLTL 637
+D V+ P + ++ +SGR GR R + +
Sbjct: 437 EVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCI 470
>Hs14591902 [R] KOG0353 ATP-dependent DNA helicase
Length = 649
Score = 60.8 bits (146), Expect = 1e-08
Identities = 103/454 (22%), Positives = 180/454 (38%), Gaps = 74/454 (16%)
Query: 202 ARVPKKKDFMDPIESMLQAKKNIETEVVNEAGDSRPTIPILLEKIKHSSIYNDQ-ITNSY 260
A V + +D I S L A + E+ + +L +KIK +D +N Y
Sbjct: 2 ASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTKKIKQCLEDSDAGASNEY 61
Query: 261 IIPERIAKYGELEFALSPEVYQALE----YKDFYSHQAAAINCIHKGENVIITTSTSSGK 316
A + + +F S +V L+ + F Q IN G+ V + T GK
Sbjct: 62 --DSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLVMPTGGGK 119
Query: 317 SLIYQLSAIDALLKDPHSTFMYIFPTKALAQDQKRSFQKL---------LSKIPELSHVI 367
SL YQL A L D + + I P +L +DQ ++L S + V
Sbjct: 120 SLCYQLPA---LCSDGFT--LVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVH 174
Query: 368 VDTYDGDTEQQARAGIRISARVIFTNPDMIHTSILPNHPNWKMFLDNLRY---------V 418
+ + ++E ++I+ P+ I S KMF+ L +
Sbjct: 175 AEMVNKNSE----------LKLIYVTPEKIAKS--------KMFMSRLEKAYEARRFTRI 216
Query: 419 VVDELHIYKGFFGSHVALVMRRLVRIVKGFYKNEKLQFISCSATLKHPIQHMQDIFGIEQ 478
VDE+H + H + + I+K + N L ++ +AT H + Q I IE+
Sbjct: 217 AVDEVHCCSQW--GHDFRPDYKALGILKRQFPNASLIGLTATAT-NHVLTDAQKILCIEK 273
Query: 479 VTLINEDGSPRGTKHLVVWNPPKLSQHDRKRENFIGESAKILVQLI---IQNVRTIAFCY 535
+N P L R++ + + + +V+LI + I +C+
Sbjct: 274 CFTFTAS-----------FNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCF 322
Query: 536 VRRVCELLMKEVRIILQDMGKLQLINEVMSYRGGYSASDRRKIEQEMFHGNLRAVVSTNA 595
++ E +V + LQ++G +Y D+ + ++ ++ VV+T A
Sbjct: 323 SQKDSE----QVTVSLQNLGI-----HAGAYHANLEPEDKTTVHRKWSANEIQVVVATVA 373
Query: 596 LELGIDIGGLDSVLMCGFPLSLANFHQQSGRAGR 629
+GID + V+ S+ N++Q+SGRAGR
Sbjct: 374 FGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGR 407
>SPBC13G1.10c [A] KOG0952 DNA/RNA helicase MER3/SLH1 DEAD-box superfamily
Length = 1935
Score = 57.0 bits (136), Expect = 2e-07
Identities = 89/407 (21%), Positives = 174/407 (41%), Gaps = 51/407 (12%)
Query: 301 HKGENVIITTSTSSGKSLIYQLSAIDALLKDPHSTFMYIFPTKALAQDQKRSFQKLLSKI 360
H N+ + T SGK++ +L+ AL P S +YI P KAL +++ + + L +
Sbjct: 1148 HTDTNIFVGAPTGSGKTMAAELATWRALHNYPKSKVVYIAPMKALVKERVKDWGHRLVEP 1207
Query: 361 PELSHVIVDTYDGDTEQQARAGIRISARVIFTNPDMIHTSILPNHPNWK--MFLDNLRYV 418
+S + GDT +A +A +I T P+ +WK ++ ++ +
Sbjct: 1208 MGISMI---ELTGDTNPDVKA--VTNANIIITTPEKWDGIT----RSWKSRKYVQDVSLI 1258
Query: 419 VVDELHIYKGFFGSHVALVMRRLVRIVKGFYKNEKLQFISCSATLKHPIQHMQDI----- 473
++DE+H+ G + +++ R+ + K ++ +S + + + + +I
Sbjct: 1259 ILDEIHLLGSDRGPVLEMIVSRMNYVASQTNKKVRVLGLSTAVANANDLANWLNIRDGLF 1318
Query: 474 ---FGIEQVTL-INEDGSPRGT--KHLVVWNPP---KLSQHDRKRENFIGESAKILVQLI 524
+ V L I DG P ++ N P + H + I S++ +L
Sbjct: 1319 NFRHSVRPVPLEIYIDGFPGRAYCPRMMSMNKPAFQAIKTHSPTQPVLIFVSSRRQTRLT 1378
Query: 525 IQNVRTIAFCYV----RRVCELLMKEVRIILQDMG----KLQLINEVMSYRGGYSASDRR 576
+++ IAFC + RR + +E+ +I+ ++ KL L + + G + +D R
Sbjct: 1379 AKDL--IAFCGLEDNPRRFLYMDEEELEMIVSEVEDKSLKLALPFGIALHHAGLTEND-R 1435
Query: 577 KIEQEMFHGN-LRAVVSTNALELGIDIGG----------LDSVLMCGFPLSLANFHQQSG 625
KI +E+F N ++ +++T+ L G++ D+ + + L + Q G
Sbjct: 1436 KISEELFVNNKVQILIATSTLAWGVNTPAHLVIVKGTEYYDAKIGGYKDMDLTDVLQMLG 1495
Query: 626 RAGRRNRDSLTLVVASDSPVDQHYVAHSESLLEVDNP-ESYQDLVLD 671
RAGR D+ + + + + H L P ESY VLD
Sbjct: 1496 RAGRPQFDNSGVARIFVQDIKKSFYKH---FLHSGFPVESYLHKVLD 1539
>Hs18548973 [A] KOG0952 DNA/RNA helicase MER3/SLH1 DEAD-box superfamily
Length = 731
Score = 56.6 bits (135), Expect = 2e-07
Identities = 85/381 (22%), Positives = 157/381 (40%), Gaps = 57/381 (14%)
Query: 305 NVIITTSTSSGKSLIYQLSAIDALLKDP----HSTFMYIFPTKALAQ----DQKRSFQKL 356
N +I T SGK+++++L+ L++ P + +Y+ P KAL D K F +
Sbjct: 315 NFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDWKEKFGPI 374
Query: 357 LSKIPELSHVIVDTYDGDTEQQARAGIRISARVIFTNPDMIHTSILPNHPNWKMFLDNLR 416
EL+ GDT I+ A +I T P+ + N + L +R
Sbjct: 375 GLNCKELT--------GDTVMDDLFEIQ-HAHIIMTTPEKWDSMTRKWRDNSLVQL--VR 423
Query: 417 YVVVDELHIYKGFF-GSHVALVMRRL--VRIVKGFYKNEK----LQFISCSATLKHPIQH 469
++DE+HI K G + +V+ R+ V+ V KN ++F++ SAT+ +
Sbjct: 424 LFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAEDI 483
Query: 470 MQDIFGIEQVTL---INEDGSPRGTKHLVVWNPPKLSQHDRKRENFIGESAKILVQLIIQ 526
+ + E+ + ++E P + +V+ P +Q + K + + ++Q+
Sbjct: 484 AEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEFKFDLTLNYKIASVIQMYSD 543
Query: 527 NVRTIAFCYVRR----VCELLMKEVRIILQDMGKLQLINEVMSYR--------------- 567
T+ FC R+ +L+K+ + I+ K +L S R
Sbjct: 544 QKPTLVFCATRKGVQQAASVLVKDAKFIMTVEQKQRLQKYAYSVRDSKLRDILKDGAAYH 603
Query: 568 -GGYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSLANFHQQS-- 624
G SDR+ +E G+L + +T+ L +G+++ V+ + F + S
Sbjct: 604 HAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGLFEEYSET 663
Query: 625 ------GRAGRRNRDSLTLVV 639
GRAGR D+ V
Sbjct: 664 DILQMIGRAGRPQFDTTATAV 684
>At5g08620 [A] KOG0342 ATP-dependent RNA helicase pitchoune
Length = 563
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/401 (20%), Positives = 165/401 (40%), Gaps = 45/401 (11%)
Query: 273 EFALSPEVYQALE---YKDFYSHQAAAINCIHKGENVIITTSTSSGKSLIYQLSAIDALL 329
+F LSP + +E +K Q A + I +G++++ T +GK++ + L +I+A++
Sbjct: 84 QFPLSPLTLKGIEDAGFKTMTVVQEATLPLILQGKDILAKAKTGTGKTVAFLLPSIEAVI 143
Query: 330 KDPHST---------FMYIFPTKALAQDQKRSFQKLLSKIPELS-HVIVDTYDGDTEQQA 379
K P ++ + + PT+ LA LL P + V++ TEQ+
Sbjct: 144 KAPPASRDNRHPPIIVLVVCPTRELACQAAAEANILLKYHPSIGVQVVIGGTKLPTEQRR 203
Query: 380 RAGIRISARVIFTNPDMIHTSILPNHPNWKMFLDNLRYVVVDEL-HIYKGFFGSHVALVM 438
+ +++ P + I N + L ++ +V+DE H+ F
Sbjct: 204 LQ--KSPCQILVATPGRLKDHI-DNTSGFATRLMGVKVLVLDEADHLLDMGF-------R 253
Query: 439 RRLVRIVKGFYKNEKLQFISCSATLKHPIQHMQDIFGIEQVTLINEDGSPRGTKHLVVWN 498
R + RI+ K Q SAT+ ++ + + +N G H V
Sbjct: 254 REIERIIAAVPKQR--QTFLFSATVSDEVRQICHVALKRDHEFVNCVQEGAGETHQKVSQ 311
Query: 499 PPKLSQHDRKRENFIGESAKILVQLIIQNV--RTIAFCYVRRVCELLMKEVRIILQDMGK 556
++ DR G +L + I NV + I FC V R++ +GK
Sbjct: 312 MYMIASLDRHFSLLYG----LLKKHITDNVGYKVIIFCTTAMV-------TRLVADLLGK 360
Query: 557 LQL-INEVMSYRGGYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPL 615
L L + E+ S + S R ++ E +V+++ G+D + V+ G P
Sbjct: 361 LSLNVREIHSRK---PQSYRTRVSDEFRKSKSIILVTSDVSARGVDYPDVSLVVQMGLPS 417
Query: 616 SLANFHQQSGRAGRRNRDSLTLVVASDSPVDQHYVAHSESL 656
+ + GR GR+ ++ +++ +P ++++++ + L
Sbjct: 418 DREQYIHRLGRTGRKGKEGEGVLLL--APWEEYFLSSVKDL 456
>At5g08610 [A] KOG0342 ATP-dependent RNA helicase pitchoune
Length = 827
Score = 53.1 bits (126), Expect = 2e-06
Identities = 89/442 (20%), Positives = 179/442 (40%), Gaps = 47/442 (10%)
Query: 240 PILLEKIKHSSIYNDQITNSYI--IPERIAKYGELEFALSPEVYQALEYKDFYSH---QA 294
P++ + ++ D+ T ++ ++K +F LSP +A++ F + Q
Sbjct: 328 PLIKKAASAKAVQTDKPTGEHVKTSDSYLSKTRFDQFPLSPLSLKAIKDAGFETMTVVQE 387
Query: 295 AAINCIHKGENVIITTSTSSGKSLIYQLSAIDALLKDPHST---------FMYIFPTKAL 345
A + I +G++V+ T +GK++ + L AI+A++K P ++ + + PT+ L
Sbjct: 388 ATLPIILQGKDVLAKAKTGTGKTVAFLLPAIEAVIKSPPASRDSRQPPIIVLVVCPTREL 447
Query: 346 AQDQKRSFQKLLSKIPELS-HVIVDTYDGDTEQQARAGIRISARVIFTNPDMIHTSILPN 404
A LL P + V++ TEQ R +++ P + I N
Sbjct: 448 ASQAAAEANTLLKYHPSIGVQVVIGGTKLPTEQ--RRMQTNPCQILVATPGRLKDHI-EN 504
Query: 405 HPNWKMFLDNLRYVVVDEL-HIYKGFFGSHVALVMRRLVRIVKGFYKNEKLQFISCSATL 463
+ L ++ +V+DE H+ F R + RI+ K Q SAT+
Sbjct: 505 TSGFATRLMGVKVLVLDEADHLLDMGF-------RRDIERIIAAVPKQR--QTFLFSATV 555
Query: 464 KHPIQHMQDIFGIEQVTLINEDGSPRGTKHLVVWNPPKLSQHDRKRENFIGESAKILVQL 523
++ + + IN G H V ++ DR +L +
Sbjct: 556 PEEVRQICHVALKRDHEFINCVQEGSGETHQKVTQMYMIASLDR----HFSLLHVLLKEH 611
Query: 524 IIQNV--RTIAFCYVRRVCELLMKEVRIILQDMGKLQL-INEVMSYRGGYSASDRRKIEQ 580
I NV + I FC V R++ + +L L + E+ S + S R ++
Sbjct: 612 IADNVDYKVIIFCTTAMV-------TRLVADLLSQLSLNVREIHSRK---PQSYRTRVSD 661
Query: 581 EMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSLANFHQQSGRAGRRNRDSLTLVVA 640
E +V+++ G+D + V+ G P + + GR GR+ ++ +++
Sbjct: 662 EFRKSKAIILVTSDVSARGVDYPDVSLVVQMGLPSDREQYIHRLGRTGRKGKEGEGVLLL 721
Query: 641 SDSPVDQHYVAHSESLLEVDNP 662
+P ++++++ + L +P
Sbjct: 722 --APWEEYFMSSVKDLPITKSP 741
>YHR065c [A] KOG0330 ATP-dependent RNA helicase
Length = 543
Score = 52.8 bits (125), Expect = 3e-06
Identities = 102/467 (21%), Positives = 184/467 (38%), Gaps = 62/467 (13%)
Query: 215 ESMLQAKKNIETEVVNEAGDSRPTIPILLEKIKHSSIYNDQITNSYIIPERIAKYGELEF 274
+ +++A+K +E +E + +L K K + ++ TN E + EL
Sbjct: 74 KKLIEAEKEGGSESDSEEDATAEKKKVLKSKSKSTVSTQNENTNE---DESFESFSELN- 129
Query: 275 ALSPEVYQA---LEYKDFYSHQAAAINCIHKGENVIITTSTSSGKSLIYQLSAIDALLKD 331
L PE+ QA L Y Q+ AI +G ++I T SGK+ + + ++ L D
Sbjct: 130 -LVPELIQACKNLNYSKPTPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIPILNRLWHD 188
Query: 332 PHSTFMYIF-PTKALAQDQKRSFQKLLSKIPELSHVIVDTYDGDTEQQARAGIRISARVI 390
+ I PT+ LAQ K +F L S + S IV + QAR +R +I
Sbjct: 189 QEPYYACILAPTRELAQQIKETFDSLGSLMGVRSTCIVGGM--NMMDQARDLMR-KPHII 245
Query: 391 FTNPDMIHTSILPNHPNWKMF-LDNLRYVVVDEL-HIYKGFFGSHVALVMRRLVRIVKGF 448
P ++ + N K F L L+++V+DE + FG + +++ + +
Sbjct: 246 IATPG----RLMDHLENTKGFSLRKLKFLVMDEADRLLDMEFGPVLDRILKIIPTQERTT 301
Query: 449 Y--------KNEKLQFISCSATLKHPIQHMQDIFGIEQVTLINEDGSPRGTKHLVVWNPP 500
Y K +KLQ S + +K + + TL+ G + T + + N
Sbjct: 302 YLFSATMTSKIDKLQRASLTNPVKCAVSNKYQTVDTLVQTLMVVPGGLKNTYLIYLLN-- 359
Query: 501 KLSQHDRKRENFIGESAKILVQLIIQNVRTIAFCYVRRVCELLMKEVRIILQDMGKLQLI 560
FIG++ I + R + +C LL + D+ + Q +
Sbjct: 360 ----------EFIGKTMIIFTRTKANAER------LSGLCNLLEFSATALHGDLNQNQRM 403
Query: 561 NEVMSYRGGYSASDRRKIEQEMFHGNLRAVVSTNALELGIDIGGLDSVLMCGFPLSLANF 620
+ ++ G +R I +V+T+ G+DI +D V+ P+ ++
Sbjct: 404 GSLDLFKAG-----KRSI-----------LVATDVAARGLDIPSVDIVVNYDIPVDSKSY 447
Query: 621 HQQSGRAGRRNRDSLTLVVASDSPVDQHYVAHSESLLEVDNPESYQD 667
+ GR R R ++ + S D + E +L P+ D
Sbjct: 448 IHRVGRTARAGRSGKSISLVSQ--YDLELILRIEEVLGKKLPKESVD 492
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.137 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,025,313
Number of Sequences: 60738
Number of extensions: 2804177
Number of successful extensions: 7139
Number of sequences better than 1.0e-05: 13
Number of HSP's better than 0.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 7109
Number of HSP's gapped (non-prelim): 25
length of query: 1079
length of database: 30,389,216
effective HSP length: 117
effective length of query: 962
effective length of database: 23,282,870
effective search space: 22398120940
effective search space used: 22398120940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)