ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2649 check: MH J KOG1035 Translation, ribosomal structure and biogenesis eIF-2alpha kinase GCN2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2649 931934 926919 -1672
(1672 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR283c [J] KOG1035 eIF-2alpha kinase GCN2 1967 0.0
SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2 357 9e-98
Hs20553830 [J] KOG1035 eIF-2alpha kinase GCN2 346 2e-94
7302048 [J] KOG1035 eIF-2alpha kinase GCN2 281 8e-75
At3g59410 [J] KOG1035 eIF-2alpha kinase GCN2 220 1e-56
CE23118 [J] KOG1035 eIF-2alpha kinase GCN2 175 5e-43
Hs11125768 [J] KOG1035 eIF-2alpha kinase GCN2 148 8e-35
SPAC222.07c [J] KOG1035 eIF-2alpha kinase GCN2 140 2e-32
SPAC20G4.03c [J] KOG1035 eIF-2alpha kinase GCN2 140 2e-32
HsM4758892 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 127 2e-28
Hs21361155 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 127 2e-28
Hs6996014 [J] KOG1936 Histidyl-tRNA synthetase 122 6e-27
7296749 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 122 6e-27
Hs15029520 [J] KOG1936 Histidyl-tRNA synthetase 115 8e-25
Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 114 2e-24
SPBC2G2.12 [J] KOG1936 Histidyl-tRNA synthetase 111 9e-24
7293481 [J] KOG1936 Histidyl-tRNA synthetase 108 7e-23
At3g02760 [J] KOG1936 Histidyl-tRNA synthetase 106 3e-22
At5g57630 [T] KOG0583 Serine/threonine protein kinase 103 2e-21
At5g01810 [T] KOG0583 Serine/threonine protein kinase 103 3e-21
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 102 5e-21
At5g10930 [T] KOG0583 Serine/threonine protein kinase 100 2e-20
YPR033c [J] KOG1936 Histidyl-tRNA synthetase 100 2e-20
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 100 2e-20
At5g07070 [T] KOG0583 Serine/threonine protein kinase 100 3e-20
At2g30360 [T] KOG0583 Serine/threonine protein kinase 99 6e-20
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 98 1e-19
At5g45820 [T] KOG0583 Serine/threonine protein kinase 97 2e-19
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 97 3e-19
At2g26980 [T] KOG0583 Serine/threonine protein kinase 97 3e-19
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 96 4e-19
At5g58380 [T] KOG0583 Serine/threonine protein kinase 96 5e-19
At5g25110 [T] KOG0583 Serine/threonine protein kinase 96 5e-19
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 95 8e-19
At3g15220 [T] KOG0201 Serine/threonine protein kinase 95 1e-18
CE18695 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3 94 2e-18
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 93 3e-18
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 93 4e-18
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 93 4e-18
At1g30270 [T] KOG0583 Serine/threonine protein kinase 92 5e-18
At4g14580 [T] KOG0583 Serine/threonine protein kinase 92 7e-18
At1g01140 [T] KOG0583 Serine/threonine protein kinase 92 7e-18
YHR102w [T] KOG0201 Serine/threonine protein kinase 91 1e-17
At3g23000 [T] KOG0583 Serine/threonine protein kinase 91 1e-17
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 91 2e-17
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 91 2e-17
At5g45810 [T] KOG0583 Serine/threonine protein kinase 91 2e-17
At1g53165 [T] KOG0201 Serine/threonine protein kinase 91 2e-17
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 91 2e-17
At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase 90 3e-17
At2g38490 [T] KOG0583 Serine/threonine protein kinase 90 3e-17
YDR523c [T] KOG0201 Serine/threonine protein kinase 89 6e-17
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 89 6e-17
Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase k... 89 6e-17
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 89 8e-17
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 89 8e-17
At5g01820 [T] KOG0583 Serine/threonine protein kinase 89 8e-17
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 89 8e-17
CE06427 [J] KOG1936 Histidyl-tRNA synthetase 88 1e-16
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 88 1e-16
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 88 1e-16
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 88 1e-16
At4g30960 [T] KOG0583 Serine/threonine protein kinase 88 1e-16
At4g18700 [T] KOG0583 Serine/threonine protein kinase 88 1e-16
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 87 2e-16
CE23001 [R] KOG0589 Serine/threonine protein kinase 87 2e-16
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 87 2e-16
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 87 2e-16
At3g29160 [T] KOG0583 Serine/threonine protein kinase 87 2e-16
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 87 2e-16
YDR507c [D] KOG0588 Serine/threonine protein kinase 87 3e-16
YDR477w [T] KOG0583 Serine/threonine protein kinase 87 3e-16
CE27768 [R] KOG0586 Serine/threonine protein kinase 87 3e-16
CE23838 [R] KOG0586 Serine/threonine protein kinase 87 3e-16
YHR079c [T] KOG1027 Serine/threonine protein kinase and endoribo... 86 5e-16
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 86 5e-16
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 86 5e-16
CE06762 [T] KOG0660 Mitogen-activated protein kinase 86 5e-16
At2g34180 [T] KOG0583 Serine/threonine protein kinase 86 5e-16
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 86 7e-16
At4g24400 [T] KOG0583 Serine/threonine protein kinase 86 7e-16
7294217 [D] KOG0588 Serine/threonine protein kinase 86 7e-16
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 85 9e-16
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 85 9e-16
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 85 9e-16
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 85 9e-16
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 85 9e-16
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 85 9e-16
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 85 9e-16
Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase k... 85 9e-16
CE28643 [T] KOG0583 Serine/threonine protein kinase 85 9e-16
At2g25090 [T] KOG0583 Serine/threonine protein kinase 85 9e-16
CE28218 [D] KOG0588 Serine/threonine protein kinase 85 1e-15
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 85 1e-15
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 85 1e-15
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 84 1e-15
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 1e-15
Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase k... 84 1e-15
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 2e-15
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 84 2e-15
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 84 2e-15
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 84 2e-15
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 84 2e-15
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 2e-15
CE07458 [T] KOG0583 Serine/threonine protein kinase 84 2e-15
At1g54510 [R] KOG0589 Serine/threonine protein kinase 84 2e-15
At1g29230 [T] KOG0583 Serine/threonine protein kinase 84 2e-15
7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 84 2e-15
7291043 [T] KOG0660 Mitogen-activated protein kinase 84 2e-15
HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase k... 84 2e-15
Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase 84 2e-15
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 2e-15
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 84 2e-15
CE00847 [T] KOG0583 Serine/threonine protein kinase 84 2e-15
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 84 2e-15
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 84 2e-15
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 83 3e-15
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 83 3e-15
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 83 3e-15
At5g39440 [T] KOG0583 Serine/threonine protein kinase 83 3e-15
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 83 3e-15
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 83 3e-15
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 83 3e-15
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 83 4e-15
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 83 4e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 83 4e-15
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 83 4e-15
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 83 4e-15
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 83 4e-15
CE17284 [T] KOG0583 Serine/threonine protein kinase 83 4e-15
At5g35410 [T] KOG0583 Serine/threonine protein kinase 83 4e-15
SPBC660.14 [D] KOG0601 Cyclin-dependent kinase WEE1 82 6e-15
At3g01090 [T] KOG0583 Serine/threonine protein kinase 82 6e-15
7300224 [T] KOG0201 Serine/threonine protein kinase 82 6e-15
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 82 7e-15
SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase 82 7e-15
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 82 7e-15
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 7e-15
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 7e-15
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 82 7e-15
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 82 9e-15
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 82 9e-15
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 81 1e-14
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 81 1e-14
Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 81 1e-14
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 81 1e-14
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 81 1e-14
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 81 1e-14
At5g28290 [R] KOG0589 Serine/threonine protein kinase 81 1e-14
At2g45490 [D] KOG0580 Serine/threonine protein kinase 81 1e-14
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 1e-14
YPL150w [T] KOG0583 Serine/threonine protein kinase 81 2e-14
YLR113w [T] KOG0660 Mitogen-activated protein kinase 81 2e-14
YCL024w [T] KOG0583 Serine/threonine protein kinase 81 2e-14
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 81 2e-14
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 81 2e-14
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 81 2e-14
Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase 81 2e-14
CE07737 [T] KOG0198 MEKK and related serine/threonine protein ki... 81 2e-14
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 81 2e-14
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 81 2e-14
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 80 2e-14
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 2e-14
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 80 2e-14
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 80 2e-14
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 80 2e-14
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 80 2e-14
At3g04810 [R] KOG0589 Serine/threonine protein kinase 80 2e-14
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 80 2e-14
7290150 [T] KOG0583 Serine/threonine protein kinase 80 2e-14
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 80 3e-14
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 80 3e-14
CE24971 [T] KOG0660 Mitogen-activated protein kinase 80 3e-14
CE17343 [T] KOG0583 Serine/threonine protein kinase 80 3e-14
CE15235 [R] KOG0589 Serine/threonine protein kinase 80 3e-14
CE01583 [T] KOG0660 Mitogen-activated protein kinase 80 3e-14
At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase 80 3e-14
At3g20860 [R] KOG0589 Serine/threonine protein kinase 80 3e-14
7302464 [R] KOG0586 Serine/threonine protein kinase 80 3e-14
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 80 4e-14
Hs4506401 [T] KOG0193 Serine/threonine protein kinase RAF 80 4e-14
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 80 4e-14
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 80 4e-14
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 80 4e-14
7299438 [R] KOG0586 Serine/threonine protein kinase 80 4e-14
7290147 [T] KOG0583 Serine/threonine protein kinase 80 4e-14
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 79 5e-14
Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase 79 5e-14
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 79 5e-14
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 79 5e-14
ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases 79 5e-14
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 5e-14
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 5e-14
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 79 5e-14
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 79 5e-14
At1g64630_2 [R] KOG0584 Serine/threonine protein kinase 79 5e-14
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 79 6e-14
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 79 6e-14
CE27573 [T] KOG0198 MEKK and related serine/threonine protein ki... 79 6e-14
CE18366 [T] KOG0583 Serine/threonine protein kinase 79 6e-14
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 79 6e-14
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 79 8e-14
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 79 8e-14
Hs4506091 [T] KOG0660 Mitogen-activated protein kinase 79 8e-14
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 79 8e-14
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 79 8e-14
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 79 8e-14
YKL101w [D] KOG0588 Serine/threonine protein kinase 78 1e-13
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 78 1e-13
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 78 1e-13
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 78 1e-13
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 78 1e-13
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 78 1e-13
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 78 1e-13
CE28674 [T] KOG0201 Serine/threonine protein kinase 78 1e-13
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 78 1e-13
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 78 1e-13
CE07510 [T] KOG0201 Serine/threonine protein kinase 78 1e-13
At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase 78 1e-13
7301213 [R] KOG0589 Serine/threonine protein kinase 78 1e-13
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 78 1e-13
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 78 1e-13
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 78 1e-13
Hs20562757 [T] KOG0660 Mitogen-activated protein kinase 78 1e-13
CE29020 [T] KOG0660 Mitogen-activated protein kinase 78 1e-13
CE09940 [D] KOG0601 Cyclin-dependent kinase WEE1 78 1e-13
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 78 1e-13
At3g17510 [T] KOG0583 Serine/threonine protein kinase 78 1e-13
CE14884_1 [D] KOG0601 Cyclin-dependent kinase WEE1 78 1e-13
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 77 2e-13
At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GT... 77 2e-13
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 2e-13
At1g09600 [D] KOG0600 Cdc2-related protein kinase 77 2e-13
7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 77 2e-13
7290313 [T] KOG0193 Serine/threonine protein kinase RAF 77 2e-13
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 77 2e-13
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 77 2e-13
SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase 77 2e-13
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 77 2e-13
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 77 2e-13
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 2e-13
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 77 2e-13
At1g48260 [T] KOG0583 Serine/threonine protein kinase 77 2e-13
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 77 3e-13
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 77 3e-13
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 77 3e-13
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 77 3e-13
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 77 3e-13
At5g41990 [R] KOG0584 Serine/threonine protein kinase 77 3e-13
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 77 3e-13
At2g18170 [T] KOG0660 Mitogen-activated protein kinase 77 3e-13
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 3e-13
7298087 [T] KOG0660 Mitogen-activated protein kinase 77 3e-13
7296451 [D] KOG0600 Cdc2-related protein kinase 77 3e-13
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 77 3e-13
YKL139w [D] KOG0600 Cdc2-related protein kinase 76 4e-13
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 76 4e-13
Hs5453860 [R] KOG0594 Protein kinase PCTAIRE and related kinases 76 4e-13
Hs4506089 [T] KOG0660 Mitogen-activated protein kinase 76 4e-13
Hs15011928 [R] KOG0594 Protein kinase PCTAIRE and related kinases 76 4e-13
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 76 4e-13
ECU06g0620 [J] KOG1936 Histidyl-tRNA synthetase 76 4e-13
CE21025 [D] KOG0580 Serine/threonine protein kinase 76 4e-13
At1g02970 [D] KOG0601 Cyclin-dependent kinase WEE1 76 4e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 76 4e-13
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 76 4e-13
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 76 5e-13
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 76 5e-13
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 76 5e-13
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 76 5e-13
Hs4506085 [T] KOG0660 Mitogen-activated protein kinase 76 5e-13
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 76 5e-13
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 76 5e-13
7293601 [T] KOG0577 Serine/threonine protein kinase 76 5e-13
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 75 7e-13
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 75 7e-13
Hs5454094 [T] KOG0574 STE20-like serine/threonine kinase MST 75 7e-13
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 75 7e-13
Hs16178962 [T] KOG0574 STE20-like serine/threonine kinase MST 75 7e-13
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 7e-13
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 7e-13
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 75 7e-13
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 75 7e-13
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 75 9e-13
SPBC18H10.15 [R] KOG0663 Protein kinase PITSLRE and related kinases 75 9e-13
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 9e-13
Hs20986501 [T] KOG0660 Mitogen-activated protein kinase 75 9e-13
Hs20986497 [T] KOG0660 Mitogen-activated protein kinase 75 9e-13
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 75 9e-13
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 9e-13
At3g44200 [R] KOG0589 Serine/threonine protein kinase 75 9e-13
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 75 9e-13
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 75 9e-13
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 75 1e-12
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 75 1e-12
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 75 1e-12
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 75 1e-12
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 75 1e-12
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 75 1e-12
Hs20986499 [T] KOG0660 Mitogen-activated protein kinase 75 1e-12
Hs20128774 [T] KOG0660 Mitogen-activated protein kinase 75 1e-12
CE06686 [T] KOG0660 Mitogen-activated protein kinase 75 1e-12
At5g39420 [D] KOG0600 Cdc2-related protein kinase 75 1e-12
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 75 1e-12
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 1e-12
At1g59580 [T] KOG0660 Mitogen-activated protein kinase 75 1e-12
7302570 [R] KOG0586 Serine/threonine protein kinase 75 1e-12
7301110 [T] KOG0660 Mitogen-activated protein kinase 75 1e-12
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 75 1e-12
7297080 [T] KOG0583 Serine/threonine protein kinase 75 1e-12
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 74 2e-12
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 74 2e-12
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 74 2e-12
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 74 2e-12
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 74 2e-12
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 2e-12
At4g04710 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 2e-12
YHR082c [T] KOG0583 Serine/threonine protein kinase 74 2e-12
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 74 2e-12
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 74 2e-12
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 74 2e-12
CE28479 [T] KOG0583 Serine/threonine protein kinase 74 2e-12
CE07599 [T] KOG0576 Mitogen-activated protein kinase kinase kina... 74 2e-12
At1g03740 [D] KOG0600 Cdc2-related protein kinase 74 2e-12
YPR161c [D] KOG0600 Cdc2-related protein kinase 74 3e-12
YJL187c [D] KOG0601 Cyclin-dependent kinase WEE1 74 3e-12
SPBC19F8.07 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polyme... 74 3e-12
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 74 3e-12
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 74 3e-12
Hs4507719 [D] KOG0596 Dual specificity; serine/threonine and tyr... 74 3e-12
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 3e-12
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 74 3e-12
Hs20547712 [D] KOG0596 Dual specificity; serine/threonine and ty... 74 3e-12
CE20717 [T] KOG0583 Serine/threonine protein kinase 74 3e-12
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 74 3e-12
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 3e-12
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 3e-12
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 73 3e-12
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 73 3e-12
Hs4757868 [T] KOG0193 Serine/threonine protein kinase RAF 73 3e-12
Hs4506095 [T] KOG0665 Jun-N-terminal kinase (JNK) 73 3e-12
Hs4503069 [T] KOG0660 Mitogen-activated protein kinase 73 3e-12
Hs4502193 [T] KOG0193 Serine/threonine protein kinase RAF 73 3e-12
Hs20986523 [T] KOG0665 Jun-N-terminal kinase (JNK) 73 3e-12
Hs20986521 [T] KOG0665 Jun-N-terminal kinase (JNK) 73 3e-12
Hs20986519 [T] KOG0665 Jun-N-terminal kinase (JNK) 73 3e-12
Hs20986516 [T] KOG0660 Mitogen-activated protein kinase 73 3e-12
Hs20986514 [T] KOG0660 Mitogen-activated protein kinase 73 3e-12
Hs20986512 [T] KOG0660 Mitogen-activated protein kinase 73 3e-12
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 73 3e-12
Hs18594815 [T] KOG0193 Serine/threonine protein kinase RAF 73 3e-12
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 73 3e-12
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 73 3e-12
CE02604 [T] KOG0695 Serine/threonine protein kinase 73 3e-12
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 3e-12
7302908 [R] KOG0594 Protein kinase PCTAIRE and related kinases 73 3e-12
YPL141c [T] KOG0583 Serine/threonine protein kinase 73 4e-12
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 73 4e-12
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 73 4e-12
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 73 4e-12
SPAC2F3.15 [D] KOG0600 Cdc2-related protein kinase 73 4e-12
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 73 4e-12
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 73 4e-12
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 73 4e-12
CE26212 [T] KOG0582 Ste20-like serine/threonine protein kinase 73 4e-12
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 4e-12
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 73 4e-12
At1g18890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 73 4e-12
At1g10210 [T] KOG0660 Mitogen-activated protein kinase 73 4e-12
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 72 6e-12
SPCC18B5.03 [D] KOG0601 Cyclin-dependent kinase WEE1 72 6e-12
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 6e-12
Hs4505649 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 6e-12
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 72 6e-12
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 72 6e-12
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 6e-12
7296166 [T] KOG0614 cGMP-dependent protein kinase 72 6e-12
7290249 [R] KOG0586 Serine/threonine protein kinase 72 6e-12
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 72 6e-12
YPL209c [D] KOG0580 Serine/threonine protein kinase 72 7e-12
YLR096w [T] KOG0583 Serine/threonine protein kinase 72 7e-12
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 72 7e-12
SPBC21.07c [D] KOG0590 Checkpoint kinase and related serine/thre... 72 7e-12
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 72 7e-12
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 72 7e-12
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 72 7e-12
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 72 7e-12
CE18009 [R] KOG0594 Protein kinase PCTAIRE and related kinases 72 7e-12
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 72 7e-12
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 7e-12
At4g14780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 72 7e-12
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 72 7e-12
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 7e-12
At3g45640 [T] KOG0660 Mitogen-activated protein kinase 72 7e-12
7299437 [R] KOG0586 Serine/threonine protein kinase 72 7e-12
YBL016w [T] KOG0660 Mitogen-activated protein kinase 72 1e-11
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 72 1e-11
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 72 1e-11
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 72 1e-11
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 72 1e-11
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 72 1e-11
At4g11330 [T] KOG0660 Mitogen-activated protein kinase 72 1e-11
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 1e-11
At3g21220 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 72 1e-11
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 72 1e-11
7300413 [T] KOG0583 Serine/threonine protein kinase 72 1e-11
YDR122w [T] KOG0583 Serine/threonine protein kinase 71 1e-11
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 71 1e-11
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 71 1e-11
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 1e-11
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 71 1e-11
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 71 1e-11
At5g18500 [T] KOG1187 Serine/threonine protein kinase 71 1e-11
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 1e-11
At5g02070 [T] KOG1187 Serine/threonine protein kinase 71 1e-11
At4g26890 [T] KOG0198 MEKK and related serine/threonine protein ... 71 1e-11
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 71 1e-11
At3g19300 [T] KOG1187 Serine/threonine protein kinase 71 1e-11
At1g70430 [T] KOG0582 Ste20-like serine/threonine protein kinase 71 1e-11
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 71 1e-11
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 71 1e-11
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 71 2e-11
HsM4758928 [D] KOG0601 Cyclin-dependent kinase WEE1 71 2e-11
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 71 2e-11
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 71 2e-11
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 71 2e-11
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 71 2e-11
Hs4506081 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-11
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 71 2e-11
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 71 2e-11
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 71 2e-11
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 71 2e-11
Hs21361083 [D] KOG0601 Cyclin-dependent kinase WEE1 71 2e-11
Hs20986510 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-11
Hs20986506 [T] KOG0665 Jun-N-terminal kinase (JNK) 71 2e-11
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 71 2e-11
At4g36450 [T] KOG0660 Mitogen-activated protein kinase 71 2e-11
At2g43790 [T] KOG0660 Mitogen-activated protein kinase 71 2e-11
At2g31010 [T] KOG0192 Tyrosine kinase specific for activated (GT... 71 2e-11
At1g74330 [D] KOG0600 Cdc2-related protein kinase 71 2e-11
At1g53050 [D] KOG0600 Cdc2-related protein kinase 71 2e-11
At1g33770 [D] KOG0600 Cdc2-related protein kinase 71 2e-11
7300106 [T] KOG0690 Serine/threonine protein kinase 71 2e-11
7291442 [D] KOG0669 Cyclin T-dependent kinase CDK9 71 2e-11
SPBC11B10.09 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 2e-11
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 70 2e-11
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 70 2e-11
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 70 2e-11
Hs16160923 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 2e-11
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 70 2e-11
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 2e-11
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 70 2e-11
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 2e-11
At3g59790 [T] KOG0660 Mitogen-activated protein kinase 70 2e-11
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 3e-11
YHR030c [T] KOG0660 Mitogen-activated protein kinase 70 3e-11
Hs7706445 [T] KOG0664 Nemo-like MAPK-related serine/threonine pr... 70 3e-11
Hs7657498 [T] KOG0661 MAPK related serine/threonine protein kinase 70 3e-11
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 70 3e-11
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 70 3e-11
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 70 3e-11
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 70 3e-11
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 70 3e-11
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 70 3e-11
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 70 3e-11
ECU11g0960 [D] KOG0600 Cdc2-related protein kinase 70 3e-11
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 3e-11
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 3e-11
CE03811 [R] KOG0663 Protein kinase PITSLRE and related kinases 70 3e-11
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 70 3e-11
At5g64960 [D] KOG0600 Cdc2-related protein kinase 70 3e-11
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 3e-11
At3g58640 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 3e-11
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 70 3e-11
At2g01450 [T] KOG0660 Mitogen-activated protein kinase 70 3e-11
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 3e-11
At1g08720 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 3e-11
7303211 [T] KOG4717 Serine/threonine protein kinase 70 3e-11
7292375 [R] KOG0594 Protein kinase PCTAIRE and related kinases 70 3e-11
SPCC70.05c [D] KOG0590 Checkpoint kinase and related serine/thre... 70 4e-11
Hs4557569 [T] KOG1027 Serine/threonine protein kinase and endori... 70 4e-11
Hs21237745 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 4e-11
Hs21237742 [T] KOG0665 Jun-N-terminal kinase (JNK) 70 4e-11
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 70 4e-11
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 4e-11
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 4e-11
CE25585 [T] KOG0193 Serine/threonine protein kinase RAF 70 4e-11
CE12408 [T] KOG0661 MAPK related serine/threonine protein kinase 70 4e-11
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 70 4e-11
At5g40440 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 70 4e-11
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 4e-11
At1g56720 [T] KOG1187 Serine/threonine protein kinase 70 4e-11
At1g07880 [T] KOG0660 Mitogen-activated protein kinase 70 4e-11
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 70 4e-11
YPL140c [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 69 5e-11
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 69 5e-11
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 69 5e-11
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 69 5e-11
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 69 5e-11
Hs22065797 [T] KOG0577 Serine/threonine protein kinase 69 5e-11
>YDR283c [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1659
Score = 1967 bits (5097), Expect = 0.0
Identities = 998/1682 (59%), Positives = 1259/1682 (74%), Gaps = 33/1682 (1%)
Query: 1 MSLSNLTLSQYYEIQKLETEALQSIYMDDFTDLTKRHSSWDKHPQIIFEIGLRSQESDPA 60
MSLS+LTL QYYEIQ E EA++SIYMDDFTDLTKR SSWDK PQIIFEI LRS + +P
Sbjct: 1 MSLSHLTLDQYYEIQCNELEAIRSIYMDDFTDLTKRKSSWDKQPQIIFEITLRSVDKEPV 60
Query: 61 ECSLNLHVVLPSTYPHAAPQITFKNVINVPDGQLNKLRQEIKEIHQRSKGQEIIYEIIIA 120
E S+ LH + YP+ AP+I FKNV NV D QL L+ E K+IH S+GQEII+EI
Sbjct: 61 ESSITLHFAMTPMYPYTAPEIEFKNVQNVMDSQLQMLKSEFKKIHNTSRGQEIIFEITSF 120
Query: 121 TQDVLEDSQKHVVTDSLEDQRLQRIRDEEARMKLXXXXXXXXXXXXXXXXXXLIDEVFQK 180
TQ+ L++ Q V T SLED RLQRI++ + +++ IDE+ Q+
Sbjct: 121 TQEKLDEFQNVVNTQSLEDDRLQRIKETKEQLEKEEREKQQETIKKRSDEQRRIDEIVQR 180
Query: 181 ELAKRMDDEV-LEFSNDKEIDLLPPAELTSSGQAFVFPQLITAKLPNNSQYKFRAVIQPQ 239
EL KR DD+ L F+ ++DL PP+E +SG+A VF + I AKLPNNS +KF+AV+ P+
Sbjct: 181 ELEKRQDDDDDLLFNRTTQLDLQPPSEWVASGEAIVFSKTIKAKLPNNSMFKFKAVVNPK 240
Query: 240 SINLCDDPLSFASQMLVKPFIPAESPLYNVLKSSDQLDSIQYLLTEVILDNPYFNTSNGK 299
I L D SF+ Q LVKP+IP ESPL + L SS+ +++ YLL+E+ LDN YFNTSNGK
Sbjct: 241 PIKLTSDIFSFSKQFLVKPYIPPESPLADFLMSSEMMENFYYLLSEIELDNSYFNTSNGK 300
Query: 300 KEISLLEKDLEAVIQVNHDNVNRLYAFSVERLGRNSSTFQWKIRLLTEFAQFTTLNDIVT 359
KEI+ LEK+LE V++ HDNVNRL+ ++VER+GRN++TF WKIRLLTE+ + L D++
Sbjct: 301 KEIANLEKELETVLKAKHDNVNRLFGYTVERMGRNNATFVWKIRLLTEYCNYYPLGDLIQ 360
Query: 360 SVGFVNLATAXXXXXXXXXXXXXXHKHGISHRLIDMHTVQLSKDTDFGTTIPKLIHPSYG 419
SVGFVNLATA HK GI H+ I++ TV L KD DFG+TIPKL+H +YG
Sbjct: 361 SVGFVNLATARIWMIRLLEGLEAIHKLGIVHKCINLETVILVKDADFGSTIPKLVHSTYG 420
Query: 420 YTILSMVTRYPSKNGVKLELPNIKWIAPELVKFKGSKPQRKTDIWQLAVLFIIIISGVDT 479
YT+L+M++RYP+KNG +EL WIAPEL+KF +KPQR TDIWQL VLFI IISG D
Sbjct: 421 YTVLNMLSRYPNKNGSSVELSPSTWIAPELLKFNNAKPQRLTDIWQLGVLFIQIISGSDI 480
Query: 480 TINFSSPDEFLETVEMDDSLYEFLKKMLQPEPKQRLTPLELLPMKFLRTNIDAGINKLNL 539
+NF +P EFL++ MD++LY+ L KML +PK+RL LELLPMKFLRTNID+ IN+ NL
Sbjct: 481 VMNFETPQEFLDSTSMDETLYDLLSKMLNNDPKKRLGTLELLPMKFLRTNIDSTINRFNL 540
Query: 540 YPDSLIDNKTLSTLPSSSGSQTLRSRTASRASTDGGRRRSFNIGXXXXXXXXXXXXXYAT 599
+S +++ +L P + T+R S RRRSFN+G YA+
Sbjct: 541 VSES-VNSNSLELTPGDT--ITVRGNGGRTLSQSSIRRRSFNVGSRFSSINPATRSRYAS 597
Query: 600 DFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIRHSEEKLSTILSEVMLLASLNHRYVVR 659
DFEEIAVLG+GA+GQVVKARNALDSRYYAIKKIRH+EEKLSTILSEVMLLASLNH+YVVR
Sbjct: 598 DFEEIAVLGQGAFGQVVKARNALDSRYYAIKKIRHTEEKLSTILSEVMLLASLNHQYVVR 657
Query: 660 YYAAWLEEEQANH---DSTAIXXXXXXXXXXXXXXXXXGQGSINKSLTG--LNSNNWDFI 714
YYAAWLEE+ + +ST Q SI K+ T L+++NWDFI
Sbjct: 658 YYAAWLEEDSMDENVFESTDEESDLSESSSDFEENDLLDQSSIFKNRTNHDLDNSNWDFI 717
Query: 715 SNSFQGSYPEIVFGNSSXXXXXXXXXXXXTGVSKASASEVTGLDSSKNDTLQEDGIGDMK 774
S S YP+IVF NSS + S + + + T +S +
Sbjct: 718 SGS---GYPDIVFENSSRDDENEDLDHDTSSTSSSESQDDTDKESKSIQNVPR------- 767
Query: 775 FGRDKRSKMKSLSVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEA 834
+R+ +K ++ +KSTLFIQMEYCENRTLYDLIH+E+LN Q++EYWRLFRQILEA
Sbjct: 768 ----RRNFVKPMTAVK-KKSTLFIQMEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEA 822
Query: 835 LSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLT 894
LSYIHSQGIIHRDLKPMNIFIDESRN+KIGDFGLAKNV S D L+ DS GSS +LT
Sbjct: 823 LSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLT 882
Query: 895 SAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEF 954
SAIGTA+YVA+E++ G+YNEK+DMYSLGIIFFEMIYPF TGMERVN++KKLR++ +EF
Sbjct: 883 SAIGTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEMIYPFSTGMERVNILKKLRSVSIEF 942
Query: 955 PSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSS 1014
P DFDD K+ EKKII+LL+DHDP +RP A LL SGW+PVK+QDE+IKEALK++S+PSS
Sbjct: 943 PPDFDDNKMKVEKKIIRLLIDHDPNKRPGARTLLNSGWLPVKHQDEVIKEALKSLSNPSS 1002
Query: 1015 PWQQQVRENLFTQPYHLSSDILFDLSRSDTTPFLQLLRAQMVDEVIKIFRRHGAIENNEP 1074
PWQQQVRE+LF Q Y L++DILFD S +TPF +LR+QM +EV+KIFR+HG IENN P
Sbjct: 1003 PWQQQVRESLFNQSYSLTNDILFDNSVPTSTPFANILRSQMTEEVVKIFRKHGGIENNAP 1062
Query: 1075 PIIFPKAPIYSTQNVYEVLDRGGSVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPS 1134
P IFPKAPIY TQNVYEVLD+GG+VLQLQYDLTYPMARYLSKNP+ SKQYRMQ+V+RP
Sbjct: 1063 PRIFPKAPIYGTQNVYEVLDKGGTVLQLQYDLTYPMARYLSKNPSLISKQYRMQHVYRPP 1122
Query: 1135 ESTHSSTEPRKFGEVDFDIISNSSTDSAVHDAECLKVVDEIVSTFPVFTNTNTILVINHA 1194
+ + SS EPRKFGE+DFDIIS SS++S +DAE LK++DEI++ FPVF TNT ++NHA
Sbjct: 1123 DHSRSSLEPRKFGEIDFDIISKSSSESGFYDAESLKIIDEILTVFPVFEKTNTFFILNHA 1182
Query: 1195 DILDGVFNFCNIDKAQRSLVSHMLSQLGFGRAFKDLKIDLRSQLNISSTSLNDLELFDFR 1254
DIL+ VFNF NIDKAQR LVS MLSQ+GF R+FK++K +L++QLNISST+LNDLELFDFR
Sbjct: 1183 DILESVFNFTNIDKAQRPLVSRMLSQVGFARSFKEVKNELKAQLNISSTALNDLELFDFR 1242
Query: 1255 SDLETSKKRLSKLLVDSPYLKRIEEAFGYVSKVVDYFKPLGVTRNVVISPLSNYNNGFYK 1314
D E +KKRL KL++DSP+LK+IE++ ++SKV+ Y KPL V RNVVISPLSNYN+ FYK
Sbjct: 1243 LDFEAAKKRLYKLMIDSPHLKKIEDSLSHISKVLSYLKPLEVARNVVISPLSNYNSAFYK 1302
Query: 1315 GGIMFQSVFDNGRTRSLISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIVK 1374
GGIMF +V+D+G +R++I+AGGRYD LIS ARPSG K ++ +KAVGFNLAWET+F I +
Sbjct: 1303 GGIMFHAVYDDGSSRNMIAAGGRYDTLISFFARPSGKKSSNTRKAVGFNLAWETIFGIAQ 1362
Query: 1375 NYFKLAGGRTNKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNTVGIEVVSKLWKAGISA 1434
NYFKLA G KK + +K +WKP RC+VL+SSFSNS+L+T+G+ +++ LWK I A
Sbjct: 1363 NYFKLASGNRIKKRNRFLKDTAVDWKPSRCDVLISSFSNSLLDTIGVTILNTLWKQNIKA 1422
Query: 1435 DIVRGCFSVEDVITSAQKDGVDWIVLIKQQSYSIANTKRKYKPLKIKNLSTNFDADMDID 1494
D++R C SV+DV+T AQ+DG+DWI+LIKQQ+Y + N KRKYKPLKIK LSTN D D+D+D
Sbjct: 1423 DMLRDCSSVDDVVTGAQQDGIDWILLIKQQAYPLTNHKRKYKPLKIKKLSTNVDIDLDLD 1482
Query: 1495 EFLSLYEDSFNREA--NNDLPMKDDFFSEHDDRNKWDDNSSQERSQDGESDTISAAGP-- 1550
EFL+LY+ ++ N+ L + D + D+ +WD+NSS SQ+G+ D + A
Sbjct: 1483 EFLTLYQQETGNKSLINDSLTLGD----KADEFKRWDENSSAGSSQEGDIDDVVAGSTNN 1538
Query: 1551 QKVIFIPNPATRAKGKPSKKDKWVFEESARNASRQLIHSLSSVPIFAVDAIHDETLEIIS 1610
QKVI++PN ATR+K K +K++KWV+E++ARN+S ++H+LS+ PI VDA+ DETLEIIS
Sbjct: 1539 QKVIYVPNMATRSK-KANKREKWVYEDAARNSSNMILHNLSNAPIITVDALRDETLEIIS 1597
Query: 1611 ITSLSQKDEWLRKVFGSAANSAPRSFATNIYNNLSKEAAKGGRWAIVHCNKTGKSCVVDL 1670
ITSL+QK+EWLRKVFGS NS PRSFAT+IYNNLSKEA KG RWAI++C+KTGKS V+DL
Sbjct: 1598 ITSLAQKEEWLRKVFGSGNNSTPRSFATSIYNNLSKEAHKGNRWAILYCHKTGKSSVIDL 1657
Query: 1671 QR 1672
QR
Sbjct: 1658 QR 1659
>SPBC36B7.09 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 903
Score = 357 bits (916), Expect = 9e-98
Identities = 285/978 (29%), Positives = 467/978 (47%), Gaps = 99/978 (10%)
Query: 13 EIQKLETEALQSIYMDDFTDLTKRHSSWDKHPQIIFEIGLRSQESDPAECS-LNLHVVLP 71
EIQ+ E EAL++I+MDDF +L R++ W+ ++ I L S+ ++ + L+L + L
Sbjct: 12 EIQENEIEALKAIFMDDFEELKVRNA-WNVTNGHVYCIHLCSRSANSKSIAKLDLCIELG 70
Query: 72 STYPHAAPQITFKNVINVPDGQLNKLRQEIKEIHQRSKGQEIIYEIIIATQDVLEDSQKH 131
+YP+ P I +N NV + Q+ L ++ + G+E+I+E+ QD L D Q
Sbjct: 71 RSYPYVKPVIKLQNGENVLNSQIRFLLDKLDTKAKDLLGEEMIFELASIVQDYLNDWQSD 130
Query: 132 VVTD--SLEDQRLQRIRDEEARMKLXXXXXXXXXXXXXXXXXXLIDEVFQKELAKRMDDE 189
+ + SLE++R +++ + R ++ + Q EL +R E
Sbjct: 131 LSSQFASLEEERAVQLKHDRERAEVDLQLRLKREKDALFEEEQTLQNKIQDELQRR-SYE 189
Query: 190 VLEFSNDKEIDLLPPAELTSSGQAFVFPQLITAKLPNNSQYKFRAVIQPQSINLCDDPLS 249
+ S+ K+ + L + + F I+ + ++S F V+ +I+ +
Sbjct: 190 TPQSSSKKKTNSKETTSLETLPTSIYFDCSISVRDCHDSLVTFNRVLPLYTISHSN---- 245
Query: 250 FASQMLVKPFIPAESPLYNVLKSSDQLDSIQYLLTEVILDNPYFNTSNGKKEISLLEKDL 309
++ LVKP ES L +LL V + PY++T +GK+EI LE +L
Sbjct: 246 LSTLTLVKP----ES-------KEISLQDCVFLLRTVRISTPYWSTEDGKREIQELEYEL 294
Query: 310 EAVIQVNHDNVNRLYAFSVERLGRNSSTFQWKIRLLTEFAQFTTLNDIVTSVGFVNLATA 369
E++ + HD + +Y + +ER R + W++ +L E++ TL ++ +V +++ T
Sbjct: 295 ESLKVIRHDLLASIYEYQLERETRG---YGWRLYVLQEYSPKFTLFSLLQTVLTLDVETV 351
Query: 370 XXXXXXXXXXXXXXHKHGISHRLIDMHTVQLSKDTDFGTTIPKLIHPSYGYTILSMVTRY 429
H+ GISH+ + + V L T KL+ + T+ M +
Sbjct: 352 RAFSNNILEGLAELHRLGISHKSLHLDNVVLFHSGH--RTFAKLMDFGFTRTLRDMNASH 409
Query: 430 P---SKNGVKLELPNIKWIAPELVKFKGSKPQRKTDIWQLAVLFIIIISGVDTTINFSSP 486
P + + LP + PE+ + + RKTDIW +L + ++ G FSS
Sbjct: 410 PFNINSQSITNILPEGLY-PPEVSESSFAAASRKTDIWCFGLLVLQMLCGAHVLNKFSSL 468
Query: 487 DEFLETVE--MDDSLYEFLKKMLQPEPKQRLTPLELLPMKFLRTNIDAGINKLNLYPDSL 544
+ V + S + +++ L + ++R + ++LL +R
Sbjct: 469 KLIMTHVIPLLPGSYQDLVRRCLMRDSRKRPSAIDLLSSHVIRLG--------------- 513
Query: 545 IDNKTLSTLPSSSGSQTLRSRTASRASTDGGRRRSFNIGXXXXXXXXXXXXXYATDFEEI 604
T P G+ + +R + DG Y TDFEE+
Sbjct: 514 ----TAVLPPVEQGTFSKSARPSYGGQQDG----------IIDLLYRKSVSRYETDFEEL 559
Query: 605 AVLGKGAYGQVVKARNALDSRYYAIKKI--RHSEEKLSTILSEVMLLASLNHRYVVRYYA 662
LG+G +G+VVK +N +D R+YA+KK+ +++ S IL EVM L+ L+H +VVRYY
Sbjct: 560 EFLGRGGFGEVVKVKNRIDGRFYAVKKLVLLSDDKENSRILREVMTLSRLHHEHVVRYYT 619
Query: 663 AWLEEEQANHDSTAIXXXXXXXXXXXXXXXXXGQGSINKSLTGLNSNNWDFISNSFQGSY 722
AW+E E AN T I + S + L+S + F+ Y
Sbjct: 620 AWVETE-ANDTVTEIISSDSESLSQSLNMAVDFRQSSSLPADKLSS-----LDIHFEDDY 673
Query: 723 PEIVFGNSSXXXXXXXXXXXXTGVSKASASEVTGLDSSKNDTLQEDGIGDMKFGRDKRSK 782
NSS + E + + ++T ++G D ++ S
Sbjct: 674 ------NSS---------------ADEEDPEASDISFQYSNTSDKEGSSDKDSSIEEASS 712
Query: 783 MKSLSVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQG 842
+K+ ++ +TL+IQMEYCE +L D+I + +E WRLFRQILEAL+YIHS+G
Sbjct: 713 VKTQ--ENGLNATLYIQMEYCEKLSLQDIIRDKI---PVDEMWRLFRQILEALAYIHSRG 767
Query: 843 IIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSG-DLTSAIGTAL 901
++HRDLKP NIF+DE+RN+K+GDFGLA + QD D + + S+ DLT+ +GTAL
Sbjct: 768 MMHRDLKPGNIFLDENRNVKLGDFGLATENENYQD--NNDKWKNRQSADEDLTTGVGTAL 825
Query: 902 YVASEIITSHG--NYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFD 959
YVA E+++ Y+ KVDMYSLGII FEM F T MER+ +I +R+ + FPS F
Sbjct: 826 YVAPELLSRRNGVRYDAKVDMYSLGIILFEMCMTFSTSMERIRIIDTIRSPSISFPSTFP 885
Query: 960 DKKLHTEKKIIKLLLDHD 977
+ E K+I LL HD
Sbjct: 886 FSRASHEFKVIHCLLQHD 903
>Hs20553830 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1528
Score = 346 bits (887), Expect = 2e-94
Identities = 315/1121 (28%), Positives = 523/1121 (46%), Gaps = 143/1121 (12%)
Query: 456 KPQRKTDIWQLAVLFIIIISGVDTTINFSSPDEFLETVEMD--DSLYEFLKKMLQPEPKQ 513
K +K D+W+L +L + + G + E+ T+ D +FLKK + + K+
Sbjct: 353 KTGKKGDVWRLGLLLLSLSQGQEC-------GEYPVTIPSDLPADFQDFLKKCVCLDDKE 405
Query: 514 RLTPLELLPMKFLRTNIDAGINKLNLYPDSLIDNKTLSTLPSSSGSQTLRSRTASRASTD 573
R +P +LL F+ K+ L S D++ + + S L S A+
Sbjct: 406 RWSPQQLLKHSFINPQ-----PKMPLVEQSPEDSEGQDYVETVIPSNRLPS-----AAFF 455
Query: 574 GGRRRSFNIGXXXXXXXXXXXXXYATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKI- 632
+R F+ Y +FEE+ +LGKGA+G V+K +N LD YA+K+I
Sbjct: 456 SETQRQFS--------------RYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIP 501
Query: 633 -RHSEEKLSTILSEVMLLASLNHRYVVRYYAAWLEEEQANHDSTAIXXXXXXXXXXXXXX 691
+ + I EV LL+ L+H +VRYY AW+E H+ A
Sbjct: 502 INPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIER----HERPAGPGTPPPDSGPLAKD 557
Query: 692 XXXGQGSINKSLTGLNSNNWDFISNSFQGSYPEIVFGNSSXXXXXXXXXXXXTGVSKASA 751
+G GL+S + + P + +S +G ASA
Sbjct: 558 DRAARGQPASDTDGLDS---------VEAAAPPPILSSS--------VEWSTSGERSASA 600
Query: 752 S-EVTGLDSSKNDTLQED---GIGDMKF-------------GRDKRSKMKSL-------- 786
TG SS ++ ED G+ F D+ SK ++
Sbjct: 601 RFPATGPGSSDDEDDDEDEHGGVFSQSFLPASDSESDIIFDNEDENSKSQNQDEDCNEKN 660
Query: 787 -------SVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIH 839
SV + L+IQMEYCE TL D I + L WRLFR+IL+ L+YIH
Sbjct: 661 GCHESEPSVTTEAVHYLYIQMEYCEKSTLRDTID-QGLYRDTVRLWRLFREILDGLAYIH 719
Query: 840 SQGIIHRDLKPMNIFIDESRNIKIGDFGLA-KNVQISQDTLRRD---SFTSAGSSGDLTS 895
+G+IHRDLKP+NIF+D ++KIGDFGLA ++ S D+ + D + SG LT
Sbjct: 720 EKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFSADSKQDDQTGDLIKSDPSGHLTG 779
Query: 896 AIGTALYVASEII-TSHGNYNEKVDMYSLGIIFFEMIY-PFDTGMERVNVIKKLRN-IDV 952
+GTALYV+ E+ ++ YN+KVD++SLGIIFFEM Y P T ER+ V+ +LR+
Sbjct: 780 MVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSP 839
Query: 953 EFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQD-----ELIKEALK 1007
+FP DFDD + +K +I LL+HDP +RPTA+ LL+S +P + E++ L
Sbjct: 840 KFPEDFDDGEHAKQKSVISWLLNHDPAKRPTATELLKSELLPPPQMEESELHEVLHHTLT 899
Query: 1008 NISDPSSPWQQQVRENLFTQPYHLSSDILF--DLSRSDTTPFLQLLRAQMVDEVIKIFRR 1065
N+ + + + +F+Q + D + D+ + + + ++ + + +I+IF+R
Sbjct: 900 NVDGKA---YRTMMAQIFSQRISPAIDYTYDSDILKGNFSIRTAKMQQHVCETIIRIFKR 956
Query: 1066 HGAIENNEPPIIFPKAPIYSTQNVYEVLDRGGSVLQLQYDLTYPMARYLSKNPNTTSKQY 1125
HGA++ P ++ IY +D G ++ L +DL P ARY+++N K+Y
Sbjct: 957 HGAVQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRIPFARYVARNNILNLKRY 1016
Query: 1126 RMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDSAVHDAECLKVVDEIVSTFPVFTNT 1185
++ VFRP + P++ E FDI++ S+T+S + AE + + EI+ FP
Sbjct: 1017 CIERVFRPRKL--DRFHPKELLECAFDIVT-STTNSFLPTAEIIYTIYEIIQEFPALQER 1073
Query: 1186 NTILVINHADILDGVFNFCNIDKAQRSLVSHMLSQLGFGRAFKDLKIDLRSQLNISSTSL 1245
N + +NH +L + C I + + S V +L + + L++SS SL
Sbjct: 1074 NYSIYLNHTMLLKAILLHCGIPEDKLSQVYIILYDAVTEKLTRREVEAKFCNLSLSSNSL 1133
Query: 1246 NDLELF-DFRSDLETSKKRLSKLLVDSPYLKR-IEEAFGYVSKVVDYFKPLGVTRNVVIS 1303
L F + + DL+ ++ L+ + + ++ + +VV K LG+ V+I+
Sbjct: 1134 CRLYKFIEQKGDLQDLMPTINSLIKQKTGIAQLVKYGLKDLEEVVGLLKKLGIKLQVLIN 1193
Query: 1304 PLSNYNNGFYKGGIMFQSV-FDNGRTRS---LISAGGRYDNLISLIARPSGGKLNHIQKA 1359
L GI+FQ V F R R+ +++AGGRYD LI P L + A
Sbjct: 1194 -LGLVYKVQQHNGIIFQFVAFIKRRQRAVPEILAAGGRYDLLIPQFRGPQA--LGPVPTA 1250
Query: 1360 VGFNLAWETMFLIVKNYFKLAGGRTNKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNTV 1419
+G ++A + + V N +S+ + + C++LV S ++
Sbjct: 1251 IGVSIAIDKISAAVLN------------MEESVTISS-------CDLLVVSVGQMSMSR- 1290
Query: 1420 GIEVVSKLWKAGISADIVRG-CFSVEDVITSAQKDGVDWIVLI--KQQSYSIANTKRKYK 1476
I + KLW AGI+A+I+ S E++ + + ++ L+ K+ S+ + K +
Sbjct: 1291 AINLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKER 1350
Query: 1477 PLKIKNLSTNFDADMDIDEFLSLYEDSFN-REANNDLPMKD 1516
+ + L T D + + + D N REA+++L +++
Sbjct: 1351 QTEKRVLETEL-VDHVLQKLRTKVTDERNGREASDNLAVQN 1390
>7302048 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1589
Score = 281 bits (718), Expect = 8e-75
Identities = 245/798 (30%), Positives = 372/798 (45%), Gaps = 98/798 (12%)
Query: 599 TDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKI---RHSEEKLSTILSEVMLLASLNHR 655
T+FE + LGKGA+G V+K RN LD+R YAIK+I S + + EV LL+ LNH
Sbjct: 521 TEFEVLMYLGKGAFGDVLKVRNILDNREYAIKRIPLPARSRQLYKKMTREVELLSRLNHE 580
Query: 656 YVVRYYAAWLE--EEQANHDSTAIXXXXXXXXXXXXXXXXXGQGSINKSLTGLNSNNWDF 713
VVRY+ +W+E ++ + + + +L + + D
Sbjct: 581 NVVRYFNSWIESVDDADAAEMDKLLGGEWSQSQQDLSVKPAKSPQLGPTLEE-DEDEEDS 639
Query: 714 ISNSFQGSYPEIVFGNSSXXXXXXXXXXXXTGVSKASASEVTGLDSSKNDTLQEDGIGDM 773
S+ + G P + +S G+ ++ G + +D QED
Sbjct: 640 SSSMWNGYIPNMEDSDSD-------------GIEFVDSN---GKVAVYDDEEQEDST--- 680
Query: 774 KFGRDKRSKMKSLSVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILE 833
R K S P ++IQME+CE TL I ++L N + WRLFR+I E
Sbjct: 681 ------RGKTNS---PKPLMQVMYIQMEFCEKCTLRTAID-DNLFNDTDRLWRLFREIAE 730
Query: 834 ALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKN----VQISQDTLRRDSFTSAGS 889
L++IH QGIIHRDLKP+NIF+D IKIGDFGLA +Q + ++
Sbjct: 731 GLAHIHQQGIIHRDLKPVNIFLDSHDQIKIGDFGLATTSFLALQAHDAAPAPVNQITSAE 790
Query: 890 SGDLTSAIGTALYVASEII--TSHGNYNEKVDMYSLGIIFFEMIY-PFDTGMERVNVIKK 946
G T +GT LYVA E+ S YN+KVDMY+LGII FEM PFDT MER I
Sbjct: 791 DGTGTGKVGTTLYVAPELTGNASKSVYNQKVDMYTLGIILFEMCQPPFDTSMERAQTIMA 850
Query: 947 LRNIDVEFP-SDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVP-----VKNQDE 1000
LRN+ + P + D K K+++ LL+HDP +RPTA LL S VP E
Sbjct: 851 LRNVSINIPDAMLKDPKYEKTVKMLQWLLNHDPAQRPTAEELLISDLVPPAQLEANELQE 910
Query: 1001 LIKEALKNISDPS-----SPWQQQVRENLFTQPYHLSSD---------ILFDLSRSDTTP 1046
+++ AL N + + QQ + + YHL S I+ D P
Sbjct: 911 MLRHALANPQSKAYKNLVARCLQQESDEVLEHTYHLGSSRAMKSWNSAIIID-DIVSLNP 969
Query: 1047 FLQLLRAQMVDEVIKIFRRHGAIENNEP---PIIFPKAPIYSTQNVYEVLDRGGSVLQLQ 1103
++ ++A +V+ +FR+HGAIE + P P+ + + N ++ G V+ L
Sbjct: 970 VIEFVKA----KVVNLFRKHGAIEVDSPLLSPLSARNSTANANANAVHLMTHSGCVVVLP 1025
Query: 1104 YDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDSAV 1163
DL AR+++ N ++Y + V+R E + P++ + FDII+ +T S +
Sbjct: 1026 CDLRTQFARHVTMNSVNLIRRYCVDRVYR--EERVFNFHPKQSYDCSFDIIA-PTTGSHL 1082
Query: 1164 HDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQ--------RSLVS 1215
DAE L + EI S P N + +NH ++L + FCN+ KAQ +
Sbjct: 1083 VDAELLSLAFEITSELPRLREKNLAIRMNHTNLLRAILIFCNVPKAQYGALFEGTMDFIE 1142
Query: 1216 HMLSQLGFGRAFKDLKIDLRSQLNISSTSLNDLELFDF-----RSDLETSK-KRLSKLLV 1269
+S+ F + + R+ S+ +L D+ L +F RS ++ S K L +
Sbjct: 1143 SRISRFQFHSSITGIMEKSRT----SAQTLMDMLLANFLLTGSRSTVDDSALKSLMRGKG 1198
Query: 1270 DSPYLKRIEEAFGYVSKVVDYFKPLGVTRNVVI-SPLSNYNNGFYKGGIMFQSVFDNGRT 1328
++ L R A + VV LGV + I + L + GGI++Q D
Sbjct: 1199 EAASLAR--GALRELETVVGLAYSLGVKCPIHIWAGLPISFDRASNGGIVWQMTADLKPN 1256
Query: 1329 R----SLISAGGRYDNLI 1342
R S+++ G RYD+++
Sbjct: 1257 RSGHPSVLAIGERYDSML 1274
>At3g59410 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1271
Score = 220 bits (561), Expect = 1e-56
Identities = 199/674 (29%), Positives = 325/674 (47%), Gaps = 75/674 (11%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEY-WRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
L+IQMEYC RTL + ES N+ +++ W L RQI+E L++IH QGIIHRD P NIF
Sbjct: 566 LYIQMEYCP-RTLRQVF--ESYNHFDKDFAWHLIRQIVEGLAHIHGQGIIHRDFTPNNIF 622
Query: 855 IDESRNIKIGDFGLAKNVQISQ-DTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
D +IKIGDFGLAK +++ Q D S AGS D T GT Y A EI
Sbjct: 623 FDARNDIKIGDFGLAKFLKLEQLDQDGGFSTDVAGSGVDSTGQAGTYFYTAPEIEQDWPK 682
Query: 914 YNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLR---NIDVEFPSDFDDKKLHTEKKII 970
+EK DMYSLG++FFE+ +PF T MER ++ L+ + +++ ++F + + ++
Sbjct: 683 IDEKADMYSLGVVFFELWHPFGTAMERHVILTNLKLKGELPLKWVNEFPE-----QASLL 737
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKE----------ALKNISDPSSPWQQQV 1020
+ L+ P RP+A+ LL+ + P + L E + + S + ++V
Sbjct: 738 RRLMSPSPSDRPSATELLKHAFPPRMESELLDSEFFAVLYLCQLHMNVLGRLSVIFDEEV 797
Query: 1021 RENLFTQPYHLSSDILFDLSRSDTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPI-IFP 1079
E Q S + D S T LR +V+ ++FR+H A P+ +
Sbjct: 798 LEMKSHQSSR--SRLCADDSYIQYTEINTELRDYVVEITKEVFRQHCAKHLEVIPMRLLS 855
Query: 1080 KAPIYSTQNVYEVLDRGGSVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHS 1139
P +S + V ++L GG +L+L Y+L P ++S N ++ K+Y + +V+R + HS
Sbjct: 856 DCPQFSRKTV-KLLTNGGDMLELCYELRLPFVHWISVNQKSSFKRYEISHVYRRAIG-HS 913
Query: 1140 STEPRKFGEVDFDIISNSSTDSAVHDAECLKVVDEIVSTFPVFTNTNTILVINHADILDG 1199
P + DFDI+ + ++ +AE LKV+ +I T +F + + +NH D+LD
Sbjct: 914 PPNPCL--QADFDIVGGT---LSLTEAEVLKVIVDI--TTHIFHRGSCDIHLNHGDLLDA 966
Query: 1200 VFNFCNIDKAQRSLVSHMLSQLGFGRAFKD--------LKIDLRSQLNISSTSLNDLELF 1251
++++ I R V+ +LS +G R ++ L +L + +N L+
Sbjct: 967 IWSWAGIKAEHRRKVAELLSMMGSLRPQSSERKLKWVFIRRQLLQELKLPEAVVNRLQTV 1026
Query: 1252 --DFRSDLETSKKRL-SKLLVDSPYLKRIEEAFGYVSKVVDYFKPLGVTRNVVISPL--- 1305
F D + + RL L D P K ++E +S ++ Y + + +V I L
Sbjct: 1027 ASRFCGDADQALPRLRGALRADRPTRKALDE----LSNLLTYLRVWRIEEHVHIDVLMPP 1082
Query: 1306 --SNYNNGFYKGGIMFQSVFDNGRTRSLISAGGRYDNLISLIARPSGGKLNHIQKAVGFN 1363
S + N F++ + ++ L++ GGRYD L+ + K+N + AVG +
Sbjct: 1083 TESYHRNLFFQVFLTKENSSGTSNDGVLLAVGGRYDWLVQEVC-DREHKMN-LPGAVGVS 1140
Query: 1364 LAWETMFLIVKNYFKLAGGRTNKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNTVGIEV 1423
LA ET+F + ++ NE VLV S L +E+
Sbjct: 1141 LALETIF---------------QHLPMDLRPIRNE---VSTSVLVCSRGGGGLLVQRMEL 1182
Query: 1424 VSKLWKAGISADIV 1437
V++LW+ I A+ V
Sbjct: 1183 VAELWEKSIKAEFV 1196
Score = 66.6 bits (161), Expect = 3e-10
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 21/91 (23%)
Query: 597 YATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIRHSEEKLST--------------- 641
Y DFEE+ LG+G +G VV +N LD R YA+KKIR ++++
Sbjct: 432 YLNDFEELKPLGQGGFGHVVLCKNKLDGRQYAVKKIRLKDKEIPVNSRIIGLEYNAKSVF 491
Query: 642 ------ILSEVMLLASLNHRYVVRYYAAWLE 666
+L EV L+ L H++VVRYY AW E
Sbjct: 492 TCARYEVLREVATLSRLQHQHVVRYYQAWFE 522
>CE23118 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 1696
Score = 175 bits (444), Expect = 5e-43
Identities = 189/751 (25%), Positives = 315/751 (41%), Gaps = 87/751 (11%)
Query: 747 SKASASEVTGLDSSKNDTLQEDGIGDMKFGRDKRSKMKS----LSVKSPRKSTLFIQMEY 802
S A V +S + + + I M+ SK K + V+ PR L IQMEY
Sbjct: 727 STADEDVVFTAESEDLNAKRRESIELMEINTTTTSKSKLAIDVVPVRKPR--ILCIQMEY 784
Query: 803 CENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIK 862
C+ TL I N E WR+F ++L L Y+H +IHRD+KP+NIF+ +K
Sbjct: 785 CDRATLRQYIDENHCFNAPTEVWRIFSEVLCGLKYMHDMAMIHRDIKPLNIFLTSQNGVK 844
Query: 863 IGDFGLAKNVQIS----------------QDTLRRDSFTSAGSSGDLTSAIGTALYVASE 906
IGDFGLA +S + L + S GS T IGT LY+A E
Sbjct: 845 IGDFGLATLEAMSSKGKIVGGAAEKSTSIEAMLSPNGVKSKGSDVHQTRDIGTQLYMAPE 904
Query: 907 I----ITSHGNYNEKVDMYSLGIIFFEMIY-PFDTGMERVNVIKKLRNIDVEFPSDFD-- 959
+ + Y K+D+YS G++ FEM Y P M+RV+ + LR+ D++ PSDF
Sbjct: 905 LFVDELVHKAPYTSKIDIYSAGVVLFEMFYRPLPPSMDRVSTLNNLRD-DIKIPSDFGAG 963
Query: 960 --DKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDE-----LIKEALKNISDP 1012
++ ++ +L +P RPTA LL +P+ +++ L ++ +K
Sbjct: 964 LAAPMAGLARRTVEKMLQRNPDERPTADDLLNDEDLPMHTKEDATFRNLCEKVIKKRDGR 1023
Query: 1013 SSPW--QQQVRENLFTQ-PYHLSSDILFDLSRSDTTPFL-QLLRAQMVDEVIKIFRRHGA 1068
+ W +Q +E + T Y DI + ++ + L + LRA E KI + H +
Sbjct: 1024 MNAWLLDKQFKEEVPTSLNYCYDVDICLERAKYNNREVLVETLRA----EFCKILKIH-S 1078
Query: 1069 IENNEPPIIFPKAPIYSTQNV----YEVLDRGGSVLQLQYDLTYPMARYLSKNPNTTSKQ 1124
E + P + + +V EVLDR G + L DL R+ +N K+
Sbjct: 1079 FEKLHTHTLMPVSTALAAASVRTKPVEVLDRSGVPVALPMDLRQNFVRFCVRNSVQRMKR 1138
Query: 1125 YRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDSAVHDAECLKVVDEIVSTFPVFTN 1184
+ V+ T ++ P + E D I + ++ L + ++ + P
Sbjct: 1139 FNFGRVY---SQTSANGHPHERWECCVDCIGPQCSSPSLEAELLLVACEMMIGSLPGMKF 1195
Query: 1185 TNTILVINHADILDGVFNFCNI-DKAQRSLVS--HMLSQLGFGRAFKDLKIDLRSQLNIS 1241
T L I HA +++ + D + L+ H++S + K+ L ++
Sbjct: 1196 T---LKIGHAQLIEAQIRHLKLSDDVRAELLDALHLISVSDRPHSHKEKMDMLTPKIGAK 1252
Query: 1242 STSLNDLELFDFRSDLETSKKRLS----KLLVDSPYLKRIEEAFGYVSKVVDYFKPLGVT 1297
+ ++ L + K++++ KL VD+ + +++A + ++V FK
Sbjct: 1253 AANIITKLLIPVEDNFGAFKEKVACFRKKLKVDAARV-LVDKAIRDLEEIVGTFKFCRTE 1311
Query: 1298 R----NVVISPLSNYNNGFYKGGIMFQ-------SVFDNGR-TRSLISAGGRYDNLISLI 1345
++V + Y + G++FQ ++ +N R R + AGGRYD+ +
Sbjct: 1312 AIEQISIVYDSQTCYRPRTFGDGLLFQIQVEKPSTIANNKRGRRQNVLAGGRYDSALLRE 1371
Query: 1346 ARPSGGKLNHIQKAVGFNLAWETMFLIVKNYFKLAGGRTNKKFTKSIKVGNNEWKPKRCE 1405
P GF +A + + I + K A K N K C
Sbjct: 1372 RHPRDFVYEIPLCISGFGVAMDVVSQIRDSINKSA---------NIPKTPQNHCKVLICS 1422
Query: 1406 VLVSSFSNSILNTVGIEVVSKLWKAGISADI 1436
++ SN I T E+ KLW GI AD+
Sbjct: 1423 MVQPDGSNLI--TQKFELAKKLWSMGIEADV 1451
Score = 57.8 bits (138), Expect = 1e-07
Identities = 35/81 (43%), Positives = 45/81 (55%), Gaps = 9/81 (11%)
Query: 604 IAVLGKGAYGQVVKARNALDSRYYAIKKI---RHSEEKLSTILSEVMLLASLNHRYVVRY 660
I VLG+G +G VV RN +DS YAIK+I S++ I E A LNH +VRY
Sbjct: 494 IRVLGRGGFGDVVLVRNKMDSTDYAIKRIPLNAKSDKLNRKIAKEAKFFAKLNHPNMVRY 553
Query: 661 YAAWLE------EEQANHDST 675
Y AW E EE ++ DS+
Sbjct: 554 YYAWAEDLIPIVEETSDDDSS 574
>Hs11125768 [J] KOG1035 eIF-2alpha kinase GCN2
Length = 630
Score = 148 bits (373), Expect = 8e-35
Identities = 150/543 (27%), Positives = 232/543 (42%), Gaps = 83/543 (15%)
Query: 498 SLYEFLKKMLQPEPKQRLTPLELLPMKFLRTNIDAGINKLNLYPD-SLIDNKTLSTLPSS 556
SL E L + +P P + +LL F++ + + + + L N+ ++ L S
Sbjct: 71 SLLEHLSHVHEPNPLRSRQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRS 130
Query: 557 SGSQTLRSRTASRASTDGGRRRSFNIGXXXXXXXXXXXXXYATDFEEIAVLGKGAYGQVV 616
+ + + + R R + Y +FEE+A+LGKG YG+V
Sbjct: 131 AKERVRQDPCEDISRIQKIRSREVAL--------EAQTSRYLNEFEELAILGKGGYGRVY 182
Query: 617 KARNALDSRYYAIKKIR---HSEEKLSTILSEVMLLASLNHRYVVRYYAAWLEEE---QA 670
K RN LD +YYAIKKI ++ +L EV +LA L H +V Y+ AW+E Q
Sbjct: 183 KVRNKLDGQYYAIKKILIKGATKTVCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVIQP 242
Query: 671 NHDSTAIXXXXXXXXXXXXXXXXXGQGSINKSLTGLNSNNWDFISNSFQGSYPEIV--FG 728
D AI ++ G+ ++ S F PE FG
Sbjct: 243 RADRAAIELPSLEVLSDQEE---------DREQCGVKNDESSSSSIIFAEPTPEKEKRFG 293
Query: 729 NSSXXXXXXXXXXXXTGVSKASASEVTGLDSSKNDTLQEDGIGDMKFGRD-------KRS 781
S T + + E L+S+ LQE+G+ + +R+
Sbjct: 294 ESDTENQNNKSVKYTTNLVIRESGE---LESTLE--LQENGLAGLSASSIVEQQLPLRRN 348
Query: 782 KMKSLSVKSPRKST-----------------LFIQMEYCENRTLYDLIHTESLNNQKEEY 824
S S +S+ L IQM+ CE +L+D I N + EY
Sbjct: 349 SHLEESFTSTEESSEENVNFLGQTEAQYHLMLHIQMQLCE-LSLWDWIVER--NKRGREY 405
Query: 825 --------------WRLFRQILEALSYIHSQGIIHRDLKPMNIFI-DESRNIKIGDFGLA 869
++F++++E + YIH+ GI+HRDLKP NIF+ + +KIGDFGLA
Sbjct: 406 VDESACPYVMANVATKIFQELVEGVFYIHNMGIVHRDLKPRNIFLHGPDQQVKIGDFGLA 465
Query: 870 KN--VQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
+Q + D R+ + TS +GT LY + E + Y+ K DMYSLG++
Sbjct: 466 CTDILQKNTDWTNRNGKRTPTH----TSRVGTCLYASPEQLEG-SEYDAKSDMYSLGVVL 520
Query: 928 FEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASAL 987
E+ PF T MER V+ LR + P K+ + K I+ L + +RP+A L
Sbjct: 521 LELFQPFGTEMERAEVLTGLRT--GQLPESL-RKRCPVQAKYIQHLTRRNSSQRPSAIQL 577
Query: 988 LRS 990
L+S
Sbjct: 578 LQS 580
>SPAC222.07c [J] KOG1035 eIF-2alpha kinase GCN2
Length = 639
Score = 140 bits (353), Expect = 2e-32
Identities = 125/469 (26%), Positives = 197/469 (41%), Gaps = 65/469 (13%)
Query: 568 SRASTDGGRRRSFNIGXXXXXX-XXXXXXXYATDFEEIAVLGKGAYGQVVKARNALDSRY 626
S+ S DG R F Y DFEE ++LG+G +G V RN +D
Sbjct: 137 SKFSVDGLNVRQFRFRDLTLESWLQSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAE 196
Query: 627 YAIKKIRHSEEKLS--TILSEVMLLASLNHRYVVRYYAAWLEEE-QANHDSTAIXXXXXX 683
YA+KKI + +++S I E+ LA ++H V+RY+++W+E +A +
Sbjct: 197 YAMKKINSTFQQMSYSKIFREIKCLAKMDHPNVIRYFSSWVESTTEATQMPIVMSKNSSR 256
Query: 684 XXXXXXXXXXXGQGSINKSLTGLNSNNWDFISNSFQGSYPEIVFGNSSXXXXXXXXXXXX 743
G SI F +I+F
Sbjct: 257 VLGTSSYCDVNGMDSII------------FEPTESSALTDDILFAEDPGTESIISTSRKS 304
Query: 744 TGVSKASASEVTGLDSSKNDTLQEDGIGDMKFGR---DKRSKMKSLSVKSPRKS-TLFIQ 799
+ S +S L+S +N L + + D S +S P S ++IQ
Sbjct: 305 SYSSTTESSNFENLESPRN--LHDSNVSTFNNTTILDDDYSSSMHISKTGPTHSFIIYIQ 362
Query: 800 MEYCENRTLYDLI---HTESLNNQKEE---YWRLFRQILEALSYIHSQ-GIIHRDLKPMN 852
M+ C + LI H S KE+ + LFR I+ + Y+H +IHRD+KP N
Sbjct: 363 MQLCFDDLESYLIRRNHFLSFPLCKEQIQLHTDLFRMIINGVMYVHEGVNLIHRDIKPSN 422
Query: 853 IFIDESR----------------------NIKIGDFGLA----KNVQISQDTLRRDSFTS 886
IF+ +S KIGDFGL KN + + L R+ +
Sbjct: 423 IFLAKSLPEDRGSVPLISYNDKNDLKEYITPKIGDFGLVVENKKNTETALSFLERNHLPN 482
Query: 887 AGSSGDLTSAIGTALYVASEII----TSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVN 942
D T IGTA Y A E++ + H + +K+D +SLG++ FE+++PF T MER
Sbjct: 483 LQ---DETQHIGTATYAAPELLDAMSSQHNKFTKKIDTFSLGMVLFELLHPFQTNMERAT 539
Query: 943 VIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSG 991
++ LR ++ P +F ++ + E +I + DP +RP+ +L G
Sbjct: 540 KLQDLRRGNL--PEEFVEQHI-CESSLILWMTAKDPTKRPSLLEVLNCG 585
>SPAC20G4.03c [J] KOG1035 eIF-2alpha kinase GCN2
Length = 704
Score = 140 bits (353), Expect = 2e-32
Identities = 131/463 (28%), Positives = 201/463 (43%), Gaps = 91/463 (19%)
Query: 597 YATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIRHSEEKLST---ILSEVMLLASLN 653
YA+DFEE+ +LGKG YG V KARN D YA+KKI ST I E LA LN
Sbjct: 220 YASDFEELELLGKGGYGSVYKARNKFDGVEYALKKIPLRLRSFSTSSNIFRESRTLARLN 279
Query: 654 HRYVVRYYAAWLE-----EEQANHDSTAIXXXXXXXXXXXXXXXXXGQGSINKSLTGLNS 708
H V+R++++W+E E+Q + A ++++S +++
Sbjct: 280 HPNVIRFFSSWVELLPSSEKQIEEEPLA-----------------SADETLSQS-ADIDN 321
Query: 709 NNWDFISNSFQGSYP---EIVFGNSSXXXXXXXXXXXXTGV-------SKASASEVTGLD 758
+D + Q +YP +I+F S K + +
Sbjct: 322 FMFDMDTGLLQHTYPSSVQILFQEDSVADDLTPCYSTKNSTCNLTDLFKKEADQDYAESH 381
Query: 759 SSKNDTLQEDGIGDMKFGRDKRSKMKSLSVKSPRKST--------------LFIQMEYCE 804
+ T Q D +G + + + S S R+ L+IQM CE
Sbjct: 382 DCSSTTSQVDTLGKLAPTKSASEMLLMDSFLSEREEDECSNIPSFDQQPLCLYIQMALCE 441
Query: 805 NRTLYDL------IHTESLNNQKEEYWRLFRQILEALSYIH-SQGIIHRDLKPMNIFI-- 855
+ IH + Y LF +ILE + Y+H + ++HRDLKP NIF+
Sbjct: 442 ETLEKHINRRNKHIHGVMSKGLRNCYILLFARILEGVLYLHDAMHLVHRDLKPRNIFLSS 501
Query: 856 ---DESRNIKIGDFGLAKNVQIS-------QDTL--------------RRDSFTSAGSSG 891
E ++ + +F NV++S Q TL + D+ +S
Sbjct: 502 GVHSEPCSVCLPNFSDEDNVEVSNAYEPVNQRTLCVVPKIGDFGLVLSQSDNLEEGTNSS 561
Query: 892 DLTSAIGTALYVASEIITSH----GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKL 947
+S +GT+ Y A E+ + H N N D+Y+LGI+FFE++YPF+T MER + I L
Sbjct: 562 AESSFVGTSTYAAPELFSKHMRSVMNNNSSTDIYALGILFFELLYPFNTRMERASAIANL 621
Query: 948 RNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRS 990
+ FP DF D + E +I+ +L +RPTA+ LL S
Sbjct: 622 KK--GIFPHDFLD-SMPEEASLIRSMLSSSN-KRPTAAQLLTS 660
>HsM4758892 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 1115
Score = 127 bits (318), Expect = 2e-28
Identities = 86/248 (34%), Positives = 132/248 (52%), Gaps = 12/248 (4%)
Query: 747 SKASASEVTGLDSSKNDTLQEDGIGDMKFGRD-KRSKMKSLSVKSPRKSTLFIQMEYCEN 805
+K +A + T SS TL D ++ + L SP K L+IQM+ C
Sbjct: 834 NKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSP-KVYLYIQMQLCRK 892
Query: 806 RTLYDLIHTESLNNQKEEY--WRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKI 863
L D ++ ++E +F QI EA+ ++HS+G++HRDLKP NIF +K+
Sbjct: 893 ENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKV 952
Query: 864 GDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN-YNEKVDMYS 922
GDFGL + QD + T + T +GT LY++ E I HGN Y+ KVD++S
Sbjct: 953 GDFGLV--TAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQI--HGNSYSHKVDIFS 1008
Query: 923 LGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRP 982
LG+I FE++YPF T MERV + +RN+ +FP F +K E +++ +L P+ RP
Sbjct: 1009 LGLILFELLYPFSTQMERVRTLTDVRNL--KFPPLF-TQKYPCEYVMVQDMLSPSPMERP 1065
Query: 983 TASALLRS 990
A ++ +
Sbjct: 1066 EAINIIEN 1073
Score = 66.2 bits (160), Expect = 4e-10
Identities = 34/72 (47%), Positives = 46/72 (63%), Gaps = 2/72 (2%)
Query: 597 YATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIRHSEEKLS--TILSEVMLLASLNH 654
Y TDFE I LG+G +G V +A+N +D YAIK+IR +L+ ++ EV LA L H
Sbjct: 588 YLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEH 647
Query: 655 RYVVRYYAAWLE 666
+VRY+ AWLE
Sbjct: 648 PGIVRYFNAWLE 659
>Hs21361155 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 1115
Score = 127 bits (318), Expect = 2e-28
Identities = 86/248 (34%), Positives = 132/248 (52%), Gaps = 12/248 (4%)
Query: 747 SKASASEVTGLDSSKNDTLQEDGIGDMKFGRD-KRSKMKSLSVKSPRKSTLFIQMEYCEN 805
+K +A + T SS TL D ++ + L SP K L+IQM+ C
Sbjct: 834 NKLTAFKPTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSP-KVYLYIQMQLCRK 892
Query: 806 RTLYDLIHTESLNNQKEEY--WRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKI 863
L D ++ ++E +F QI EA+ ++HS+G++HRDLKP NIF +K+
Sbjct: 893 ENLKDWMNGRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKV 952
Query: 864 GDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN-YNEKVDMYS 922
GDFGL + QD + T + T +GT LY++ E I HGN Y+ KVD++S
Sbjct: 953 GDFGLV--TAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQI--HGNSYSHKVDIFS 1008
Query: 923 LGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRP 982
LG+I FE++YPF T MERV + +RN+ +FP F +K E +++ +L P+ RP
Sbjct: 1009 LGLILFELLYPFSTQMERVRTLTDVRNL--KFPPLF-TQKYPCEYVMVQDMLSPSPMERP 1065
Query: 983 TASALLRS 990
A ++ +
Sbjct: 1066 EAINIIEN 1073
Score = 66.2 bits (160), Expect = 4e-10
Identities = 34/72 (47%), Positives = 46/72 (63%), Gaps = 2/72 (2%)
Query: 597 YATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIRHSEEKLS--TILSEVMLLASLNH 654
Y TDFE I LG+G +G V +A+N +D YAIK+IR +L+ ++ EV LA L H
Sbjct: 588 YLTDFEPIQCLGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEH 647
Query: 655 RYVVRYYAAWLE 666
+VRY+ AWLE
Sbjct: 648 PGIVRYFNAWLE 659
>Hs6996014 [J] KOG1936 Histidyl-tRNA synthetase
Length = 509
Score = 122 bits (305), Expect = 6e-27
Identities = 106/413 (25%), Positives = 199/413 (47%), Gaps = 53/413 (12%)
Query: 1043 DTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPIYS-----TQNVYEVLDRGG 1097
D +P +R ++ D +I+ F+RHGA E + P+ K + ++ +Y++ D+GG
Sbjct: 64 DYSPRQMAVREKVFDVIIRCFKRHGA-EVIDTPVFELKETLMGKYGEDSKLIYDLKDQGG 122
Query: 1098 SVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNS 1157
+L L+YDLT P ARYL+ N T K+Y + V+R + R+F + DFDI N
Sbjct: 123 ELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGN- 181
Query: 1158 STDSAVHDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQRSLVSHM 1217
D + DAECLK++ EI+S+ + + ++ +N ILDG+F C + ++ +
Sbjct: 182 -FDPMIPDAECLKIMCEILSSLQI---GDFLVKVNDRRILDGMFAICGVSDSKFRTICSS 237
Query: 1218 LSQLGFGRAFKDLKIDLRSQLNISSTSLNDLELFDFRSDL--ETSKKRLSKLLVDSPYL- 1274
+ +L +++++K ++ + ++ E+ D D + L + L+ P L
Sbjct: 238 VDKLD-KVSWEEVKNEMVGEKGLAP------EVADRIGDYVQQHGGVSLVEQLLQDPKLS 290
Query: 1275 --KRIEEAFGYVSKVVDYFKPLGVTRNVVISPLSNYNNGFYKGGIMFQSVFDNGRTRS-- 1330
K+ E G + + +Y G+ + LS Y G+++++V ++
Sbjct: 291 QNKQALEGLGDLKLLFEYLTLFGIDDKISFD-LSLARGLDYYTGVIYEAVLLQTPAQAGE 349
Query: 1331 ------LISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIVKNYFKLAGGRT 1384
++AGGRYD L+ + P G K+ VG ++ E +F IV+
Sbjct: 350 EPLGVGSVAAGGRYDGLVGMF-DPKGRKV----PCVGLSIGVERIFSIVE---------- 394
Query: 1385 NKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNTVGIEVVSKLWKAGISADIV 1437
+ ++ + + +VLV+S +L +++VS+LW AGI A+++
Sbjct: 395 -----QRLEALEEKIRTTETQVLVASAQKKLLEE-RLKLVSELWDAGIKAELL 441
>7296749 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 1141
Score = 122 bits (305), Expect = 6e-27
Identities = 71/202 (35%), Positives = 109/202 (53%), Gaps = 5/202 (2%)
Query: 787 SVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHR 846
+V P K L+IQM+ C +L D + + +F QI++A+ Y+H +G+IHR
Sbjct: 899 TVAKPSKVYLYIQMQLCRKESLRDWLRDNRSETRAAHIGDIFHQIVDAVDYVHLKGLIHR 958
Query: 847 DLKPMNIFIDESRNIKIGDFGLAKNV-QISQDTLRRDSFTSAGSSGDLTSAIGTALYVAS 905
DLKP NIF + IKIGDFGL ++ I + + S T +GT LY++
Sbjct: 959 DLKPSNIFFSQDGQIKIGDFGLVTDMADIPNLVAKCGDQSGLPSCARHTQQVGTHLYMSP 1018
Query: 906 EIITSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHT 965
E + +Y+ KVD+YSLG+IFFE+ F T MER+ ++ LR D ++P DF
Sbjct: 1019 EQLLGQ-HYDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSLR--DGQYPKDF-AVNYPQ 1074
Query: 966 EKKIIKLLLDHDPVRRPTASAL 987
+ +++ +L P +RP L
Sbjct: 1075 QYDLLQQMLSAQPEQRPQTKQL 1096
Score = 58.9 bits (141), Expect = 7e-08
Identities = 29/72 (40%), Positives = 42/72 (58%), Gaps = 2/72 (2%)
Query: 597 YATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIR--HSEEKLSTILSEVMLLASLNH 654
+ +DFE + LG+G +G V +A+N LD YAIK+I + E +L E LAS H
Sbjct: 617 FQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQRVLREARTLASCEH 676
Query: 655 RYVVRYYAAWLE 666
+VRY+ +W E
Sbjct: 677 HNIVRYFHSWTE 688
>Hs15029520 [J] KOG1936 Histidyl-tRNA synthetase
Length = 506
Score = 115 bits (287), Expect = 8e-25
Identities = 115/474 (24%), Positives = 223/474 (46%), Gaps = 59/474 (12%)
Query: 1043 DTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPI--YSTQN--VYEVLDRGGS 1098
D +P ++R +++D VI F+RHGA + P + Y + +Y++ D+GG
Sbjct: 65 DLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGE 124
Query: 1099 VLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSS 1158
+L L+YDLT P ARYL+ N K+Y + V+R T R+F + DFDI
Sbjct: 125 LLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA--GQ 182
Query: 1159 TDSAVHDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQRSLVSHML 1218
D + DAECLK++ EI+S + + ++ +N I+DG+F C + +++ + +
Sbjct: 183 FDPMIPDAECLKIMCEILSGLQL---GDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSI 239
Query: 1219 SQLGFGRAFKDLKIDLRSQLNISSTSLNDLELFDFRSDLETSKKRLS--KLLVDSPYL-- 1274
+L A+KD++ ++ + ++ E+ D D +S + + P L
Sbjct: 240 DKLD-KMAWKDVRHEMVVKKGLAP------EVADRIGDYVQCHGGVSLVEQMFQDPRLSQ 292
Query: 1275 -KRIEEAFGYVSKVVDYFKPLGVTRNVVISPLSNYNNGFYKGGIMFQSVFDNGRTRS--- 1330
K+ E G + + +Y G+ + LS Y G+++++V T++
Sbjct: 293 NKQALEGLGDLKLLFEYLTLFGIADKISFD-LSLARGLDYYTGVIYEAVLLQTPTQAGEE 351
Query: 1331 -----LISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIVKNYFKLAGGRTN 1385
++AGGRYD L+ + P G K+ VG ++ E +F IV+ K
Sbjct: 352 PLNVGSVAAGGRYDGLVGMF-DPKGHKV----PCVGLSIGVERIFYIVEQRMK------- 399
Query: 1386 KKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNTVGIEVVSKLWKAGISADIV-RGCFSVE 1444
TK KV E +V V++ + L ++++++LW +GI A+++ + +
Sbjct: 400 ---TKGEKVRTTE-----TQVFVATPQKNFLQE-RLKLIAELWDSGIKAEMLYKNNPKLL 450
Query: 1445 DVITSAQKDGVDWIVLIKQQSYSIANTKRKYKPLKIKNLSTNFDADMDIDEFLS 1498
+ + G+ +V+I +Q + K +KI+++++ + + + F++
Sbjct: 451 TQLHYCESTGIPLVVIIGEQ-------ELKEGVIKIRSVASREEVAIKRENFVA 497
>Hs4506103 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 551
Score = 114 bits (284), Expect = 2e-24
Identities = 82/219 (37%), Positives = 115/219 (52%), Gaps = 29/219 (13%)
Query: 787 SVKSPRKST--LFIQMEYCENRTLYDLIHTESLNN-QKEEYWRLFRQILEALSYIHSQGI 843
S S R T LFIQME+C+ TL I K LF QI + + YIHS+ +
Sbjct: 351 SKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKL 410
Query: 844 IHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYV 903
IHRDLKP NIF+ +++ +KIGDFGL TS + G T + GT Y+
Sbjct: 411 IHRDLKPSNIFLVDTKQVKIGDFGLV---------------TSLKNDGKRTRSKGTLRYM 455
Query: 904 ASEIITSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKL 963
+ E I+S +Y ++VD+Y+LG+I E+++ DT E LR+ + SD DKK
Sbjct: 456 SPEQISSQ-DYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGII---SDIFDKK- 510
Query: 964 HTEKKIIKLLLDHDPVRRPTASALLRSGWV----PVKNQ 998
EK +++ LL P RP S +LR+ V P KN+
Sbjct: 511 --EKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNE 547
Score = 58.5 bits (140), Expect = 9e-08
Identities = 26/68 (38%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Query: 597 YATDFEEIAVLGKGAYGQVVKARNALDSRYYAIKKIRHSEEKLSTILSEVMLLASLNHRY 656
+ DF+EI ++G G +GQV KA++ +D + Y IK+++++ EK EV LA L+H
Sbjct: 263 FGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAE---REVKALAKLDHVN 319
Query: 657 VVRYYAAW 664
+V Y W
Sbjct: 320 IVHYNGCW 327
>SPBC2G2.12 [J] KOG1936 Histidyl-tRNA synthetase
Length = 538
Score = 111 bits (278), Expect = 9e-24
Identities = 113/472 (23%), Positives = 202/472 (41%), Gaps = 78/472 (16%)
Query: 1050 LLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPIYS------TQNVYEVLDRGGSVLQLQ 1103
+LR + V +IF+RHG + + P +F I S ++ +Y++ D+GG + L+
Sbjct: 78 VLREHIFSTVTEIFKRHGGVTLDTP--VFELKEILSGKYGEDSKLIYDLKDQGGELCSLR 135
Query: 1104 YDLTYPMARYLSKNPNTTS-KQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDSA 1162
YDLT P AR+L+ NP TS K++ + V+R + + R+F + DFDI N D
Sbjct: 136 YDLTVPFARWLAMNPKVTSIKRFHIAKVYRRDQPAMTKGRMREFYQCDFDIAGN--YDPM 193
Query: 1163 VHDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQRSLVSHMLSQLG 1222
+ D+E LKV+ E + V N + +NH ILDG+F C + + +S + +L
Sbjct: 194 IPDSEALKVLVEALDALEV---GNYTIKLNHRKILDGIFTVCGVPDDKIRTISSAVDKLD 250
Query: 1223 FGRAFKDLKIDLRSQLNISSTSLNDLELFDFRSDLETSKKRLSKLLVDSPYLKRIE--EA 1280
++D++ ++ + + + ++ + L+ + L KL DS A
Sbjct: 251 -KLPWEDVRREMVVEKGLKEEVADKIKEYVL---LKGDRSLLDKLEADSLLSSNSSAVAA 306
Query: 1281 FGYVSKVVDYFKPLGVTRNVVISPLSNYNNGFYKGGIMFQSVFDNGRTR----------- 1329
F + + DY + GV +S Y GI++++V + +
Sbjct: 307 FNDMRLLFDYLEAFGVLDRFSFD-MSLARGLDYYTGIIYEAVTEASAPKIKSSAEKKKSA 365
Query: 1330 --------------SLISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIVKN 1375
I+AGGRYDNL+ + A K+ VG +L E +F I+++
Sbjct: 366 DPEADRSNDDSIGVGSIAAGGRYDNLVGMFAAKKNAKI----PCVGISLGLERIFSILRS 421
Query: 1376 YFKLAGGRTNKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNT----VGIEVVSKLWKAG 1431
K+ + + + +V V +F T + V LW G
Sbjct: 422 -----------------KIPDEDIRANDVDVFVMAFGGGKEWTGFLKERMSVCKDLWANG 464
Query: 1432 ISADIVRGCFSVE----DVITSAQKDGVDWIVLIKQQSYSIANTKRKYKPLK 1479
I A+ + + V+ +A K V + V++ Q ++ + + K LK
Sbjct: 465 IKAEFL---YKVKPKPRQQFDAADKFDVPFAVILGQDEFAKGSVRIKQMGLK 513
>7293481 [J] KOG1936 Histidyl-tRNA synthetase
Length = 522
Score = 108 bits (270), Expect = 7e-23
Identities = 102/422 (24%), Positives = 195/422 (46%), Gaps = 62/422 (14%)
Query: 1043 DTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPIYS-----TQNVYEVLDRGG 1097
D P LR ++D+++++F+RHG E + P+ K + ++ +Y++ D+GG
Sbjct: 67 DYGPQQMTLRQGVLDKIVQVFKRHGG-EAIDTPVFELKEVLTGKYGEDSKLIYDLKDQGG 125
Query: 1098 SVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNS 1157
+L ++YDLT P+ARYL+ N ++ K+Y + V+R + R+F + DFDI
Sbjct: 126 EILSMRYDLTVPLARYLAMNKISSIKRYHIAKVYRRDNPAMTKGRYREFYQCDFDIA--G 183
Query: 1158 STDSAVHDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQRSLVSHM 1217
+ D + DAEC+K+V EI+ T + + ++ +NH +LDG+F C + +
Sbjct: 184 TYDPMLPDAECVKIVSEILDTLDI---GDYVIKLNHRQLLDGMFQACGVPADSFRTICSA 240
Query: 1218 LSQLGFGRAFKDLKIDLRSQLNISSTSLNDLELFDFRSDLETS-KKRLSKLLVDSPYLKR 1276
+ +L K D+R ++ + L++ + S L + L+ + LK
Sbjct: 241 VDKLD-----KSPWADVRKEM-VDEKGLDEAAADRIGEYVRLSGGAELVEQLLANEKLKA 294
Query: 1277 IEEA---FGYVSKVVDYFKPLGVTRNV-----VISPLSNYNNGFYKGGIMFQSVF----- 1323
+ A + +++ Y G+ + V + L Y Y+G + +S
Sbjct: 295 VPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATVASPA 354
Query: 1324 ----DNGR------TRSLISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIV 1373
NG T ++ GGRYDNL+ + P G + VG ++ E +F ++
Sbjct: 355 KTSQQNGEQANEPATVGSVAGGGRYDNLVGMF-DPRGKAV----PCVGVSIGVERIFSVL 409
Query: 1374 KNYFKLAGGRTNKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNTVGIEVVSKLWKAGIS 1433
+ +G +K+ ++ EV V+S ++ L+ ++V++ LW AG+
Sbjct: 410 EARAAASG----------LKLRTSD-----VEVYVAS-AHKGLHEQRLKVLNLLWDAGVK 453
Query: 1434 AD 1435
A+
Sbjct: 454 AE 455
>At3g02760 [J] KOG1936 Histidyl-tRNA synthetase
Length = 479
Score = 106 bits (265), Expect = 3e-22
Identities = 108/424 (25%), Positives = 198/424 (46%), Gaps = 43/424 (10%)
Query: 1051 LRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPI----YSTQNVYEVLDRGGSVLQLQYDL 1106
+R + + +F+RHGA + P + + ++ VY++ D+GG + L+YDL
Sbjct: 58 VREKAFSIIQNVFKRHGATALDTPVFELRETLMGKYGEDSKLVYDIADQGGELCSLRYDL 117
Query: 1107 TYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDSAVHDA 1166
T P ARY++ N T+ K+Y++ V+R S R+F + DFDI + D
Sbjct: 118 TVPFARYVAMNGITSFKRYQIAKVYR--RDNPSKGRYREFYQCDFDIA--GLFEPMGPDF 173
Query: 1167 ECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQRSLVSHMLSQLGFGRA 1226
E +K++ E++ + + + +NH +LDG+ C + + + + +L ++
Sbjct: 174 EIVKILTELLDELEI---GDYEVKLNHRKLLDGMLEICGVPPEKFRTICSSIDKLD-KQS 229
Query: 1227 FKDLKIDLRSQLNISSTSLNDLELFDFRSDLETSKKRLSKLLVD-SPYL--KRIEEAFGY 1283
F+ +K ++ + +SS + + +F + + LSKL + S +L + EA
Sbjct: 230 FEQVKKEMVEEKGLSSEIAD--RIGNFVKEKGAPLELLSKLRQEGSEFLDNQSSREALDE 287
Query: 1284 VSKVVDYFKPLGVTRNVVISPLSNYNNGFYKGGIMFQSVFDNGRTRSLISAGGRYDNLIS 1343
+S + + K + +V LS Y G++F++V S I AGGRYDNLI
Sbjct: 288 LSIMFEALKRSKCSERIVFD-LSLARGLDYYTGVIFEAVCIGAEVGS-IGAGGRYDNLIG 345
Query: 1344 LIARPSGGKLNHIQKAVGFNLAWETMFLIVKNYFKLAGGRTNKKFTKSIKVGNNEWKPKR 1403
+ AVG +L E +F I++ N+K + I +P
Sbjct: 346 MFGTKQ-------VPAVGMSLGIERVFNIME--------ELNEKQKQVI-------RPTE 383
Query: 1404 CEVLVSSFSNSILNTVGIEVVSKLWKAGISADIVRGCFSVEDVITSAQKDGVDWIVLIKQ 1463
+VLVS ++ L E+VS+LW A I+A+ + E A++ G+ W+V++ +
Sbjct: 384 TQVLVSIMVDNKL-AEAAELVSQLWGAKINAEYLVS-KRKEKHFNRAKESGIPWMVMVGE 441
Query: 1464 QSYS 1467
+ S
Sbjct: 442 KELS 445
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 103 bits (258), Expect = 2e-21
Identities = 70/229 (30%), Positives = 123/229 (53%), Gaps = 34/229 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ + I MEY L D + + + ++ + +LF+Q+++A+ Y H++G+ HRDLKP N
Sbjct: 82 KTKICIVMEYVSGGQLSDRLGRQKM--KESDARKLFQQLIDAVDYCHNRGVYHRDLKPQN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGD-LTSAIGTALYVASEIITSH 911
+ +D N+K+ DFGL ++ SGD L++A G+ Y+A E+I +
Sbjct: 140 LLLDSKGNLKVSDFGL----------------SAVPKSGDMLSTACGSPCYIAPELIMNK 183
Query: 912 GNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G VD++S G+I FE++ PFD V + KK+ D FP F + +K+
Sbjct: 184 GYSGAAVDVWSCGVILFELLAGYPPFDDHTLPV-LYKKILRADYTFPPGFTGE----QKR 238
Query: 969 IIKLLLDHDPVRRPTASALL------RSGWVPVKNQ-DELIKEALKNIS 1010
+I +LD +P+ R T + ++ + G+ PV +Q + IK+ + I+
Sbjct: 239 LIFNILDPNPLSRITLAEIIIKDSWFKIGYTPVYHQLSDSIKDNVAEIN 287
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 103 bits (256), Expect = 3e-21
Identities = 68/219 (31%), Positives = 119/219 (54%), Gaps = 25/219 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS ++ ME+ + L++ + T L + F+Q++ A+ + HS+G+ HRDLKP N
Sbjct: 82 KSKIYFVMEHVKGGELFNKVSTGKLREDVAR--KYFQQLVRAVDFCHSRGVCHRDLKPEN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE N+KI DFGL+ D+ R+D G L + GT YVA E+I+ +G
Sbjct: 140 LLLDEHGNLKISDFGLS----ALSDSRRQD--------GLLHTTCGTPAYVAPEVISRNG 187
Query: 913 NYNEKVDMYSLGIIFFEMI---YPF-DTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
K D++S G+I F ++ PF D+ + + + KK+ +V+FP+ K+
Sbjct: 188 YDGFKADVWSCGVILFVLLAGYLPFRDSNL--MELYKKIGKAEVKFPNWL----APGAKR 241
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALK 1007
++K +LD +P R + +++S W K E +KE+++
Sbjct: 242 LLKRILDPNPNTRVSTEKIMKSSWFR-KGLQEEVKESVE 279
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 102 bits (254), Expect = 5e-21
Identities = 76/255 (29%), Positives = 129/255 (49%), Gaps = 34/255 (13%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S+L++ +E CE L+D I + ++ E + ++++AL YIHS G+IHRD+KP N+
Sbjct: 112 SSLYMALESCEGGELFDQITRKGRLSEDEARFYT-AEVVDALEYIHSMGLIHRDIKPENL 170
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS--- 910
+ +IKI DFG K +Q SQ T+ +A S + +GTA YV E++ S
Sbjct: 171 LLTSDGHIKIADFGSVKPMQDSQITV----LPNAASDDKACTFVGTAAYVPPEVLNSSPA 226
Query: 911 -HGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
GN D+++LG ++M+ PF E + + +++ D++FP+ F +
Sbjct: 227 TFGN-----DLWALGCTLYQMLSGTSPFKDASEWL-IFQRIIARDIKFPNHFSE----AA 276
Query: 967 KKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNI---------SDPSSPWQ 1017
+ +I LLD +P RRP A + G+V +K KN+ DP+S
Sbjct: 277 RDLIDRLLDTEPSRRPGAGS---EGYVALKRHPFFNGVDWKNLRSQTPPKLAPDPASQTA 333
Query: 1018 QQVRENLFTQPYHLS 1032
R++ P++L+
Sbjct: 334 SPERDDTHGSPWNLT 348
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 100 bits (250), Expect = 2e-20
Identities = 67/205 (32%), Positives = 107/205 (51%), Gaps = 24/205 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ +F ME+ + L+ I L+ R F+Q++ A+ Y HS+G+ HRDLKP N
Sbjct: 83 KTKIFFVMEFVKGGELFCKISKGKLHEDAAR--RYFQQLISAVDYCHSRGVSHRDLKPEN 140
Query: 853 IFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+ +DE+ ++KI DFGL A QI QD G L + GT YVA E++
Sbjct: 141 LLLDENGDLKISDFGLSALPEQILQD-------------GLLHTQCGTPAYVAPEVLKKK 187
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G K D++S G++ + ++ PF +N+ +K+ D EFP F + ++
Sbjct: 188 GYDGAKADIWSCGVVLYVLLAGCLPFQ-DENLMNMYRKIFRADFEFPPWFSPE----ARR 242
Query: 969 IIKLLLDHDPVRRPTASALLRSGWV 993
+I LL DP RR + A++R+ W+
Sbjct: 243 LISKLLVVDPDRRISIPAIMRTPWL 267
>YPR033c [J] KOG1936 Histidyl-tRNA synthetase
Length = 546
Score = 100 bits (249), Expect = 2e-20
Identities = 118/479 (24%), Positives = 206/479 (42%), Gaps = 76/479 (15%)
Query: 1050 LLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPIYS------TQNVYEVLDRGGSVLQLQ 1103
++R + + +F++HG + + P +F I + ++ +Y + D+GG + L+
Sbjct: 70 VIREAIFSTLSGLFKKHGGVTIDTP--VFELREILAGKYGEDSKLIYNLEDQGGELCSLR 127
Query: 1104 YDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDSAV 1163
YDLT P ARY++ N + K+Y + V+R + + R+F + DFD+ + +S V
Sbjct: 128 YDLTVPFARYVAMNNIQSIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDVA--GTFESMV 185
Query: 1164 HDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCN------------IDKAQR 1211
D+ECL ++ E +++ + + + +NH ILDG+F +DK +
Sbjct: 186 PDSECLSILVEGLTSLGI---KDFKIKLNHRKILDGIFQIAGVKDEDVRKISSAVDKLDK 242
Query: 1212 S----LVSHMLSQLGFGRAFKDLKIDLRSQLNISSTSLNDLELFDFRSDLETSKKRLSKL 1267
S + M + G D KI +LN S ++ + D TS ++ +
Sbjct: 243 SPWEAVKKEMTEEKGQSEETAD-KIGEYVKLNGSLKEIHAVLSADANI---TSNEKAKQG 298
Query: 1268 LVDSPYLKRIEEAFGY---------VSKVVDYFKPLGVTRNVVISPLSNYNNG--FYKGG 1316
L D L + EAF +++ +DY+ G+ VV S + N K
Sbjct: 299 LDDIATLMKYTEAFDIDSFISFDLSLARGLDYY--TGLIYEVVTSASAPPENASELKKKA 356
Query: 1317 IMFQSVFDNGRTRSLISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIVKNY 1376
+ + S I+AGGRYDNL+++ + SG K I VG + E +F ++K
Sbjct: 357 KSAEDASEFVGVGS-IAAGGRYDNLVNMFSEASGKKSTQI-PCVGISFGVERIFSLIKQ- 413
Query: 1377 FKLAGGRTNKKFTKSIKVGNNEWKPKRCEVLVSSFSNSILNT----VGIEVVSKLWKAGI 1432
R N T KP +V V +F T ++V +LW AGI
Sbjct: 414 ------RINSSTT---------IKPTATQVFVMAFGGGKDWTGYLPERMKVTKQLWDAGI 458
Query: 1433 SADIV-RGCFSVEDVITSAQKDGVDWIVLIKQQSYSIANTKRKYKPLKIKNLSTNFDAD 1490
A+ V + + +A+K G V++ ++ Y L++K L F D
Sbjct: 459 EAEYVYKAKANPRKQFDAAEKAGCHIAVILGKEEYLEGK-------LRVKRLGQEFADD 510
>CE02602_1 [T] KOG0660 Mitogen-activated protein kinase
Length = 342
Score = 100 bits (249), Expect = 2e-20
Identities = 72/238 (30%), Positives = 126/238 (52%), Gaps = 20/238 (8%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
++I M+ E L L ++LN + +Y+ F QIL+ L Y+HS GIIHRDLKP N+ +
Sbjct: 120 IYIVMDLMETDLLSVLKSNQTLNEKHFQYF--FYQILKGLKYLHSAGIIHRDLKPANLLL 177
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+E ++KI DFG++++ ++ T ++ +A SGDL+ + T Y A EI+ S G Y+
Sbjct: 178 NEDCSLKIADFGMSRSGPSTKTT--PNTSPNAHISGDLSQYVSTLWYRAPEILLSMGEYD 235
Query: 916 EKVDMYSLGIIFFEMIY--PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK--KIIK 971
+VD++S G I EM+ P TG + + I+ L +E+ D++ + K I
Sbjct: 236 TQVDIWSAGCILAEMLLLRPIFTGTDSYSQIQLL----IEYLGTPDEQVIRRIKSPSIRD 291
Query: 972 LLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQPY 1029
+ P +A+ + + +N ++ + L+ SPW++ E L +P+
Sbjct: 292 YISSFGPKTPLPFTAMFPNASIEARN---IVSKMLQ-----ISPWKRFSAEQLLEEPF 341
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 100 bits (248), Expect = 3e-20
Identities = 66/241 (27%), Positives = 123/241 (50%), Gaps = 30/241 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS ++ +EYC+ L++ + L +++ W+ F Q++ A+ + HS+G+ HRD+KP N
Sbjct: 82 KSRIYFVIEYCKGGELFNKVAKGKL--KEDVAWKYFYQLISAVDFCHSRGVYHRDIKPEN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D++ N+K+ DFGL+ D R+D G L + GT YVA E+I G
Sbjct: 140 LLLDDNDNLKVSDFGLS----ALADCKRQD--------GLLHTTCGTPAYVAPEVINRKG 187
Query: 913 NYNEKVDMYSLGIIFFEMI---YPF-DTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
K D++S G++ F ++ PF DT + + + +K+ D + PS F + K+
Sbjct: 188 YEGTKADIWSCGVVLFVLLAGYLPFHDTNL--MEMYRKIGKADFKCPSWFAPE----VKR 241
Query: 969 IIKLLLDHDPVRRPTASALLRSGW------VPVKNQDELIKEALKNISDPSSPWQQQVRE 1022
++ +LD + R T + + S W + K +++ K+ ++ ++P E
Sbjct: 242 LLCKMLDPNHETRITIAKIKESSWFRKGLHLKQKKMEKMEKQQVREATNPMEAGGSGQNE 301
Query: 1023 N 1023
N
Sbjct: 302 N 302
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 99.0 bits (245), Expect = 6e-20
Identities = 66/203 (32%), Positives = 104/203 (50%), Gaps = 21/203 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS +F ME+ + L++ I ++ R F+Q++ A+ Y H++G+ HRDLKP N
Sbjct: 92 KSKIFFAMEFVKGGELFNKISKHGRLSEDLSR-RYFQQLISAVGYCHARGVYHRDLKPEN 150
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ IDE+ N+K+ DFGL+ D +R D G L + GT YVA EI++ G
Sbjct: 151 LLIDENGNLKVSDFGLS----ALTDQIRPD--------GLLHTLCGTPAYVAPEILSKKG 198
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
KVD++S GI+ F ++ PF+ +N+ KK+ + FP K+
Sbjct: 199 YEGAKVDVWSCGIVLFVLVAGYLPFN-DPNVMNMYKKIYKGEYRFPRWMSPDL----KRF 253
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
+ LLD +P R T +L+ W
Sbjct: 254 VSRLLDINPETRITIDEILKDPW 276
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 98.2 bits (243), Expect = 1e-19
Identities = 65/204 (31%), Positives = 103/204 (49%), Gaps = 25/204 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K + I MEY LYD I +E + E FRQI+ A+ Y H G++HRDLK N
Sbjct: 125 KDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLEN 183
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
I +D++ NIKI DFGL+ Q +D F L + G+ LY + EI+
Sbjct: 184 ILLDDNCNIKIADFGLSNLYQ-------KDKF--------LQTFCGSPLYASPEIVNGRP 228
Query: 913 NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD ++LG++ + ++Y PFD G + N+I+++ + + P+ D + +
Sbjct: 229 YRGPEVDSWALGVLLYTLVYGTMPFD-GFDHKNLIRQISSGEYREPTQPSD-----ARGL 282
Query: 970 IKLLLDHDPVRRPTASALLRSGWV 993
I+ +L +P RR T + WV
Sbjct: 283 IRWMLMVNPDRRATIEDIANHWWV 306
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 97.4 bits (241), Expect = 2e-19
Identities = 65/230 (28%), Positives = 111/230 (48%), Gaps = 29/230 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ ++ MEY + L+D + L + F+Q++ A+ Y HS+G+ HRDLKP N
Sbjct: 82 KTKIYFAMEYVKGGELFDKVSKGKLKENIAR--KYFQQLIGAIDYCHSRGVYHRDLKPEN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE+ ++KI DFGL+ LR S G L + GT YVA E+I G
Sbjct: 140 LLLDENGDLKISDFGLS--------ALRE----SKQQDGLLHTTCGTPAYVAPEVIGKKG 187
Query: 913 NYNEKVDMYSLGIIFFEMIYPFDTGMER--VNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
K D++S G++ + ++ F E+ V + +K+ + + P+ F + KK++
Sbjct: 188 YDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPE----VKKLL 243
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQV 1020
+LD +P R ++ + W ++ K I P SP Q+
Sbjct: 244 SRILDPNPNSRIKIEKIMENSW---------FQKGFKKIETPKSPESHQI 284
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 96.7 bits (239), Expect = 3e-19
Identities = 62/195 (31%), Positives = 96/195 (48%), Gaps = 34/195 (17%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+++ MEYC N LYD + E ++K R+ Q+ A+ Y+H QG +HRDLK NIF+
Sbjct: 98 IYLAMEYCPNGELYDWVAREKRLDEKTTC-RIMWQLCCAIQYLHRQGCVHRDLKLENIFL 156
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D++ N+K+GDFG +++ S+ T + + GT Y A E++ H
Sbjct: 157 DKAYNVKLGDFGFSRDSDCSRRTF-------------MNTRCGTVAYCAPELVQGHKYIG 203
Query: 916 EKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLD 975
E VD++SLGII + ++ P D DD L TE+KII
Sbjct: 204 ECVDIWSLGIIMYALLIG-------------------RLPFDEDDVSL-TEQKIINECPQ 243
Query: 976 HDPVRRPTASALLRS 990
+ +S+LL+S
Sbjct: 244 YPETLSKNSSSLLKS 258
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 96.7 bits (239), Expect = 3e-19
Identities = 71/257 (27%), Positives = 122/257 (46%), Gaps = 26/257 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ +FI +EY L+D I + +++E R F+Q++ A+ Y HS+G+ HRDLKP N
Sbjct: 84 KTKIFIILEYVTGGELFDKIVNDG-RMKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPEN 142
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D N+KI DFGL+ Q +D G L ++ GT YVA E++ G
Sbjct: 143 LLLDSYGNLKISDFGLSALSQQVRD------------DGLLHTSCGTPNYVAPEVLNDRG 190
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
DM+S G++ + ++ PFD +N+ KK+ + + P + K+
Sbjct: 191 YDGATADMWSCGVVLYVLLAGYLPFDDS-NLMNLYKKISSGEFNCPPWLSLGAM----KL 245
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFT--- 1026
I +LD +P+ R T + W + + +E + D + E+L T
Sbjct: 246 ITRILDPNPMTRVTPQEVFEDEWFKKDYKPPVFEERDDSNMDDIDAVFKDSEEHLVTEKR 305
Query: 1027 --QPYHLSSDILFDLSR 1041
QP +++ + +SR
Sbjct: 306 EEQPAAINAFEIISMSR 322
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 96.3 bits (238), Expect = 4e-19
Identities = 64/199 (32%), Positives = 108/199 (54%), Gaps = 22/199 (11%)
Query: 795 TLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+L++ +E CE L+D I + ++ E + ++++AL YIH+ G+IHRD+KP N+
Sbjct: 114 SLYMALESCEGGELFDQITRKGRLSEDEARF-YSAEVVDALEYIHNMGLIHRDIKPENLL 172
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS---- 910
+ +IKI DFG K +Q SQ T+ +A S + +GTA YV E++ S
Sbjct: 173 LTLDGHIKIADFGSVKPMQDSQITV----LPNAASDDKACTFVGTAAYVPPEVLNSSPAT 228
Query: 911 HGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
GN D+++LG ++M+ PF E + + +++ D++FP+ F + +
Sbjct: 229 FGN-----DLWALGCTLYQMLSGTSPFKDASEWL-IFQRIIARDIKFPNHFSE----AAR 278
Query: 968 KIIKLLLDHDPVRRPTASA 986
+I LLD DP RRP A +
Sbjct: 279 DLIDRLLDTDPSRRPGAGS 297
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 95.9 bits (237), Expect = 5e-19
Identities = 58/203 (28%), Positives = 105/203 (51%), Gaps = 22/203 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ ++ MEYC+ L++ + L + + W+ F Q++ A+ + HS+ + HRD+KP N
Sbjct: 82 KTRIYFVMEYCKGGELFNKVAKGKLRD--DVAWKYFYQLINAVDFCHSREVYHRDIKPEN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D++ N+K+ DFGL+ D R+D G L + GT YVA E+I G
Sbjct: 140 LLLDDNENLKVSDFGLS----ALADCKRQD--------GLLHTTCGTPAYVAPEVINRKG 187
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
K D++S G++ F ++ PF + + +K+ D + PS F + +++
Sbjct: 188 YDGTKADIWSCGVVLFVLLAGYLPFHDS-NLMEMYRKIGKADFKAPSWFAPE----VRRL 242
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
+ +LD +P R T + + S W
Sbjct: 243 LCKMLDPNPETRITIARIRESSW 265
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 95.9 bits (237), Expect = 5e-19
Identities = 66/204 (32%), Positives = 105/204 (51%), Gaps = 24/204 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ +F MEY + L+ I L + F+Q++ A+ + HS+G+ HRDLKP N
Sbjct: 85 KTKIFFIMEYVKGGELFSKIVKGKLKEDSAR--KYFQQLISAVDFCHSRGVSHRDLKPEN 142
Query: 853 IFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+ +DE+ ++K+ DFGL A QI QD G L + GT YVA E++
Sbjct: 143 LLVDENGDLKVSDFGLSALPEQILQD-------------GLLHTQCGTPAYVAPEVLRKK 189
Query: 912 GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI---DVEFPSDFDDKKLHTEKK 968
G K D++S GII + ++ F + N++K R I + E+P F + K+
Sbjct: 190 GYDGAKGDIWSCGIILYVLLAGF-LPFQDENLMKMYRKIFKSEFEYPPWFSPE----SKR 244
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
+I LL DP +R + A++R+ W
Sbjct: 245 LISKLLVVDPNKRISIPAIMRTPW 268
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 95.1 bits (235), Expect = 8e-19
Identities = 67/218 (30%), Positives = 113/218 (51%), Gaps = 27/218 (12%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
+ +++ +E CE+++L +L+ + E + L QIL AL Y+H + +IHRDLK NI
Sbjct: 111 TNIYLILELCEHKSLMELLRKRKQLTEPEVRY-LMMQILGALKYMHKKRVIHRDLKLGNI 169
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEII-TSHG 912
+DES N+KIGDFGLA + D R+ + GT Y+A EI+ S
Sbjct: 170 MLDESNNVKIGDFGLA--ALLMDDEERK------------MTICGTPNYIAPEILFNSKE 215
Query: 913 NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
++ +VD++S G++ + ++ PF E + +K++ FPS+ D K +
Sbjct: 216 GHSFEVDLWSAGVVMYALLIGKPPFQ-DKEVKTIYRKIKANSYSFPSNVDISA--EAKDL 272
Query: 970 IKLLLDHDPVRRPTASALL-----RSGWVPVKNQDELI 1002
I LL HDP RP+ ++ +G++ DE++
Sbjct: 273 ISSLLTHDPSIRPSIDDIVDHEFFHTGYMASTLPDEIL 310
>At3g15220 [T] KOG0201 Serine/threonine protein kinase
Length = 690
Score = 94.7 bits (234), Expect = 1e-18
Identities = 62/217 (28%), Positives = 113/217 (51%), Gaps = 20/217 (9%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEE--YWRLFRQILEALSYIHSQGIIHRDLKP 850
++ L+I MEY ++ DL+ + NN +E + R +L A+ Y+H++G IHRD+K
Sbjct: 83 QTKLWIIMEYMAGGSVADLLQS---NNPLDETSIACITRDLLHAVEYLHNEGKIHRDIKA 139
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
NI + E+ ++K+ DFG+ + Q+++ RR +F +GT ++A E+I +
Sbjct: 140 ANILLSENGDVKVADFGV--SAQLTRTISRRKTF------------VGTPFWMAPEVIQN 185
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YNEK D++SLGI EM + + ++ ++ L I E P D+ K+ +
Sbjct: 186 SEGYNEKADIWSLGITVIEMA-KGEPPLADLHPMRVLFIIPRETPPQLDEHFSRQVKEFV 244
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALK 1007
L L P RP+A L++ ++ + + E ++
Sbjct: 245 SLCLKKAPAERPSAKELIKHRFIKNARKSPKLLERIR 281
>CE18695 [J] KOG1033 eIF-2alpha kinase PEK/EIF2AK3
Length = 1077
Score = 94.0 bits (232), Expect = 2e-18
Identities = 65/197 (32%), Positives = 102/197 (50%), Gaps = 17/197 (8%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYW--RLFRQILEALSYIHSQGIIHRDLKPMNI 853
L+I M+ C +TL D I + + +Q+ L Y+H++G IHRDLKP N+
Sbjct: 880 LYIVMQLCAEKTLEDWIRRSKTMESRPLFTMKNWIKQLASGLEYLHNKGFIHRDLKPGNV 939
Query: 854 F--IDESRN---IKIGDFGLA-KNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
F +D + +KIGD GLA K + T+R+DS SS T +GT Y++ E
Sbjct: 940 FFSLDSTHGHQILKIGDLGLATKTDGAPKITVRQDS----DSSAKHTKNVGTRSYMSPEQ 995
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
+ H Y EKVD+++LG++ E+I F T ER++ + D+ P+ D+ + +
Sbjct: 996 L-KHQQYTEKVDIFALGLVATELIISFSTASERIHTFADFQKGDI--PAILDN--VPESR 1050
Query: 968 KIIKLLLDHDPVRRPTA 984
+ L +P RPTA
Sbjct: 1051 DFLLQLTSLEPSERPTA 1067
Score = 53.9 bits (128), Expect = 2e-06
Identities = 33/107 (30%), Positives = 54/107 (49%), Gaps = 20/107 (18%)
Query: 562 LRSRTASRASTDGGRRRSFNIGXXXXXXXXXXXXXYATDFEEIAVLGKGAYGQVVKARNA 621
LR+RT SR+S +G R +A +FE V+G G +G V +A++
Sbjct: 583 LRNRTISRSSLEGFTSR------------------FANEFEVKKVIGHGGFGVVFRAQSI 624
Query: 622 LDSRYYAIKKI--RHSEEKLSTILSEVMLLASLNHRYVVRYYAAWLE 666
D YA+K+I +++ + +L E LA +H ++RY+ AW E
Sbjct: 625 TDMNEYAVKRIAVADNDKARNRVLREARALAMFDHPGIIRYFYAWEE 671
>Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase
Length = 330
Score = 93.2 bits (230), Expect = 3e-18
Identities = 65/203 (32%), Positives = 110/203 (54%), Gaps = 29/203 (14%)
Query: 794 STLFIQMEYCENRTLYDLI--HTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
+TL I++EYC LYD I + L ++ W LF QI+ A+S IH GI+HRD+K +
Sbjct: 122 TTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLF-QIVSAVSCIHKAGILHRDIKTL 180
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
NIF+ ++ IK+GD+GLAK + ++ A + +GT Y++ E+
Sbjct: 181 NIFLTKANLIKLGDYGLAKKL--------NSEYSMA------ETLVGTPYYMSPELCQG- 225
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMER---VNVIKKLRNIDVEFPSDFDDKKLHT 965
YN K D++++G + FE++ FD V +++ +R ++V+ S + + +
Sbjct: 226 VKYNFKSDIWAVGCVIFELLTLKRTFDATNPLNLCVKIVQGIRAMEVD-SSQYSLELI-- 282
Query: 966 EKKIIKLLLDHDPVRRPTASALL 988
+++ LD DP +RPTA LL
Sbjct: 283 --QMVHSCLDQDPEQRPTADELL 303
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 92.8 bits (229), Expect = 4e-18
Identities = 68/206 (33%), Positives = 108/206 (52%), Gaps = 28/206 (13%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
S ++I +E C N +L +L+ + + E R F QI A+ Y+HS+ +IHRDLK N
Sbjct: 152 SNVYILLEICPNGSLMELLKRRKVLTEPEV--RFFTTQICGAIKYMHSRRVIHRDLKLGN 209
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT-SH 911
IF D + N+KIGDFGLA A S + GT Y+A E++ H
Sbjct: 210 IFFDSNYNLKIGDFGLAA--------------VLANESERKYTICGTPNYIAPEVLMGKH 255
Query: 912 GNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVI-KKLRNIDVEFPSDFDDKKLHTEK 967
++ +VD++SLG++ + ++ PF VN I ++++ D FP DK + E
Sbjct: 256 SGHSFEVDIWSLGVMLYALLIGKPPFQA--RDVNTIYERIKCRDFSFPR---DKPISDEG 310
Query: 968 KI-IKLLLDHDPVRRPTASALLRSGW 992
KI I+ +L DP+ RP+ + ++ W
Sbjct: 311 KILIRDILSLDPIERPSLTEIMDYVW 336
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 405
Score = 92.8 bits (229), Expect = 4e-18
Identities = 81/273 (29%), Positives = 125/273 (45%), Gaps = 38/273 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS +++ ME L+D I + +K+ L RQILEA+ Y+H QG++HRDLKP N
Sbjct: 115 KSKVYLVMELVTGGELFDRIVEKGSYTEKDAS-HLIRQILEAVDYMHEQGVVHRDLKPEN 173
Query: 853 IFI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
+ D+ I I DFGL+K SG + +A GT YVA E++
Sbjct: 174 LLYYSPDDDSKIMISDFGLSK----------------MEDSGIMATACGTPGYVAPEVL- 216
Query: 910 SHGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
+ Y + VD++S+G+I + ++ YP N+ ++ D EF S + D+ + K
Sbjct: 217 AQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAK 276
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV-----PVKNQDELIKEALKNISDPSSPWQQ---- 1018
IK L+ +R T L W+ +N + E LK + S W+Q
Sbjct: 277 HFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKK-NFAKSRWKQAYYA 335
Query: 1019 -QVRENLFTQPYHLSSDILFDLSRS----DTTP 1046
V + + +S+ FD S S TTP
Sbjct: 336 ATVIRQMQRMALNSNSNANFDSSNSSNQDSTTP 368
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 92.4 bits (228), Expect = 5e-18
Identities = 59/203 (29%), Positives = 103/203 (50%), Gaps = 23/203 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ ++ +E+ L+D I + +++E + F+Q++ A+ Y HS+G+ HRDLKP N
Sbjct: 101 KTKIYFVLEFVTGGELFDKISSNG-RLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPEN 159
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D + +K+ DFGL+ Q G L + GT YVA E+I + G
Sbjct: 160 LLLDANGALKVSDFGLSALPQ--------------QEDGLLHTTCGTPNYVAPEVINNKG 205
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
K D++S G+I F ++ PF+ ++ KK+ + P F + KK+
Sbjct: 206 YDGAKADLWSCGVILFVLMAGYLPFEDS-NLTSLYKKIFKAEFTCPPWFS----ASAKKL 260
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
IK +LD +P R T + ++ + W
Sbjct: 261 IKRILDPNPATRITFAEVIENEW 283
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 92.0 bits (227), Expect = 7e-18
Identities = 64/204 (31%), Positives = 97/204 (47%), Gaps = 23/204 (11%)
Query: 793 KSTLFIQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
KS +++ +EY L+ LI LN R F+Q+ ALS+ H GI HRD+KP
Sbjct: 92 KSKIYLVVEYAAGGELFTKLIRFGRLNESAAR--RYFQQLASALSFCHRDGIAHRDVKPQ 149
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
N+ +D+ N+K+ DFGL+ + ++G L +A GT Y A E+I
Sbjct: 150 NLLLDKQGNLKVSDFGLSALPE------------HRSNNGLLHTACGTPAYTAPEVIAQR 197
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G K D +S G+ F ++ PFD V + +K+ D FPS +
Sbjct: 198 GYDGAKADAWSCGVFLFVLLAGYVPFDDA-NIVAMYRKIHKRDYRFPSWIS----KPARS 252
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
II LLD +P R + A++ + W
Sbjct: 253 IIYKLLDPNPETRMSIEAVMGTVW 276
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 92.0 bits (227), Expect = 7e-18
Identities = 61/204 (29%), Positives = 106/204 (51%), Gaps = 23/204 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ ++I +E L+D I + +++E R F+Q++ A+ Y HS+G+ HRDLKP N
Sbjct: 89 KTKIYIVLELVNGGELFDKIAQQG-RLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPEN 147
Query: 853 IFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+ +D + +K+ DFGL A + Q+ +D G L +A GT YVA E+++
Sbjct: 148 LILDANGVLKVSDFGLSAFSRQVRED-------------GLLHTACGTPNYVAPEVLSDK 194
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G D++S G+I F ++ PFD + + K++ + P F K+
Sbjct: 195 GYDGAAADVWSCGVILFVLMAGYLPFDE-PNLMTLYKRICKAEFSCPPWFS----QGAKR 249
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
+IK +L+ +P+ R + + LL W
Sbjct: 250 VIKRILEPNPITRISIAELLEDEW 273
>YHR102w [T] KOG0201 Serine/threonine protein kinase
Length = 1080
Score = 91.3 bits (225), Expect = 1e-17
Identities = 65/204 (31%), Positives = 107/204 (51%), Gaps = 20/204 (9%)
Query: 792 RKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKP 850
+ ++L+I ME+C +L L+ ++ E+Y + R++L AL IH +IHRD+K
Sbjct: 91 KDTSLWIIMEHCAGGSLRSLLRPGKID---EKYIGVIMRELLVALKCIHKDNVIHRDIKA 147
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
N+ I N+K+ DFG+A Q++Q +LRR + GT ++A E+I
Sbjct: 148 ANVLITNEGNVKLCDFGVA--AQVNQTSLRRQTMA------------GTPYWMAPEVIME 193
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE-KKI 969
Y+ KVD++SLGI +E I + V ++ ++ I P +D+ T K+
Sbjct: 194 GVYYDTKVDIWSLGITTYE-IATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEF 252
Query: 970 IKLLLDHDPVRRPTASALLRSGWV 993
I L LD DP R +A LL+S ++
Sbjct: 253 IALCLDEDPKERLSADDLLKSKFI 276
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 91.3 bits (225), Expect = 1e-17
Identities = 60/203 (29%), Positives = 96/203 (46%), Gaps = 22/203 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS +++ ME L+ + + R F+Q+ AL + H G+ HRD+KP N
Sbjct: 96 KSKIYLVMELASGGELFSKVLRRGRLPESTAR-RYFQQLASALRFSHQDGVAHRDVKPQN 154
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE N+K+ DFGL+ + Q +G L +A GT Y A E+I+ G
Sbjct: 155 LLLDEQGNLKVSDFGLSALPEHLQ-------------NGLLHTACGTPAYTAPEVISRRG 201
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
K D +S G+I F ++ PFD + +K+ D FPS + K I
Sbjct: 202 YDGAKADAWSCGVILFVLLVGDVPFDDS-NIAAMYRKIHRRDYRFPSWISKQ----AKSI 256
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
I +LD +PV R + ++++ W
Sbjct: 257 IYQMLDPNPVTRMSIETVMKTNW 279
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 514
Score = 90.9 bits (224), Expect = 2e-17
Identities = 64/250 (25%), Positives = 125/250 (49%), Gaps = 36/250 (14%)
Query: 789 KSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDL 848
++P+K +++ ME CE+ L +++ + ++ E W + + + A++Y+H+ I+HRDL
Sbjct: 183 ETPKK--MYLVMELCEDGELKEILDRKGHFSENETRW-IIQSLASAIAYLHNNDIVHRDL 239
Query: 849 KPMNIFIDES---------RNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGT 899
K NI + S NIK+ DFGLA Q + + L + GT
Sbjct: 240 KLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAM-------------LQATCGT 286
Query: 900 ALYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPS 956
+Y+A E+I++H +Y+++ D++S+G++ + ++ PF E + + +R ++ F +
Sbjct: 287 PIYMAPEVISAH-DYSQQCDIWSIGVVMYMLLRGEPPFLASSEE-KLFELIRKGELHFEN 344
Query: 957 DFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPW 1016
+ K ++K L+ DP R TA LL + W+ ++L N+ + W
Sbjct: 345 AVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWL---TGNKLSSVRPTNVLEMMKEW 401
Query: 1017 Q---QQVREN 1023
+ + V EN
Sbjct: 402 KNNPESVEEN 411
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 370
Score = 90.5 bits (223), Expect = 2e-17
Identities = 68/233 (29%), Positives = 115/233 (49%), Gaps = 28/233 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF- 854
L++ M+ L+D I + +++ RL Q+L+A+ Y+H GI+HRDLKP N+
Sbjct: 91 LYLIMQLVSGGELFDRIVEKGFYTERDAS-RLIFQVLDAVKYLHDLGIVHRDLKPENLLY 149
Query: 855 --IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+DE I I DFGL+K GS L++A GT YVA E++ +
Sbjct: 150 YSLDEDSKIMISDFGLSK-------------MEDPGSV--LSTACGTPGYVAPEVL-AQK 193
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
Y++ VD +S+G+I + ++ YP + +++ + EF S + D + K I
Sbjct: 194 PYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253
Query: 971 KLLLDHDPVRRPTASALLRSGWVP-----VKNQDELIKEALKNISDPSSPWQQ 1018
+ L++ DP +R T L+ W+ KN + + E +K + S W+Q
Sbjct: 254 RHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKK-NFAKSKWKQ 305
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 90.5 bits (223), Expect = 2e-17
Identities = 66/204 (32%), Positives = 106/204 (51%), Gaps = 24/204 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKPM 851
KS ++ MEY + L++ + L KEE R F+Q++ A+S+ H +G+ HRDLKP
Sbjct: 98 KSKIYFVMEYVKGGELFNKVAKGRL---KEEMARKYFQQLISAVSFCHFRGVYHRDLKPE 154
Query: 852 NIFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
N+ +DE+ N+K+ DFGL A + QI QD G + GT YVA E++
Sbjct: 155 NLLLDENGNLKVSDFGLSAVSDQIRQD-------------GLFHTFCGTPAYVAPEVLAR 201
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMER--VNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G KVD++S G+I F ++ F +R + + KK+ D P F + +
Sbjct: 202 KGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMAMYKKIYRGDFRCPRWF---PVEINRL 258
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
+I+ +L+ P RR T ++ + W
Sbjct: 259 LIR-MLETKPERRFTMPDIMETSW 281
>At1g53165 [T] KOG0201 Serine/threonine protein kinase
Length = 1007
Score = 90.5 bits (223), Expect = 2e-17
Identities = 61/217 (28%), Positives = 109/217 (50%), Gaps = 20/217 (9%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR--LFRQILEALSYIHSQGIIHRDLKP 850
++ L+I MEY ++ DL+ N +E + R +L A+ Y+H++G IHRD+K
Sbjct: 410 QTKLWIIMEYMAGGSVADLLQP---GNPLDEISIACITRDLLHAVEYLHAEGKIHRDIKA 466
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
NI + E+ ++K+ DFG+ + Q+++ RR +F +GT ++A E+I +
Sbjct: 467 ANILLSENGDVKVADFGV--SAQLTRTISRRKTF------------VGTPFWMAPEVIQN 512
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YNEK D++SLGI EM + + ++ ++ L I E P D+ K+ +
Sbjct: 513 SEGYNEKADIWSLGITMIEMA-KGEPPLADLHPMRVLFIIPRESPPQLDEHFSRPLKEFV 571
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALK 1007
L P RP A LL+ ++ + + E ++
Sbjct: 572 SFCLKKAPAERPNAKELLKHRFIKNARKSPKLLERIR 608
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 90.5 bits (223), Expect = 2e-17
Identities = 74/292 (25%), Positives = 130/292 (44%), Gaps = 33/292 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K + + MEY LYD + + + + E R+FRQI A+ Y H + HRDLK N
Sbjct: 145 KDKIILVMEYSSGGELYDYV-SRCGSLPEAEARRIFRQITSAVLYCHKHRVAHRDLKLEN 203
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
I +D++ N KI DFGL+ LT+ G+ LY + EII
Sbjct: 204 ILLDQNNNAKIADFGLSNYF---------------ADKNLLTTFCGSPLYASPEIINGTP 248
Query: 913 NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD +SLGI+ + ++Y PFD G + ++++++ + F+ + T +
Sbjct: 249 YKGPEVDCWSLGILLYTLVYGSMPFD-GRDFNRMVRQIKR-----GAYFEPETPSTASML 302
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQPY 1029
I+ +L +P RR T + W+ ++ +I+E +N +P ++ E + Q
Sbjct: 303 IRNMLRVNPERRATIFDIASHWWLNLEENMPVIQELPENQIIDHTPLTER-EETMIVQDL 361
Query: 1030 HLSSDILFDLSRSDTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPIIFPKA 1081
D+ + + ++ E +I R+ N+ P+ PKA
Sbjct: 362 ADEQDVFMEFGHLSSETRRKI-------EDFRIRRKEAEEFNDNSPVKPPKA 406
>At4g14480 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 487
Score = 90.1 bits (222), Expect = 3e-17
Identities = 62/232 (26%), Positives = 120/232 (51%), Gaps = 22/232 (9%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPMNIF 854
L++ M + +L+ ++ + + E +F ++ L A+SY+H QG +HRD+K NI
Sbjct: 87 LWVVMPFMSCGSLHSIVSSSFPSGLPENCISVFLKETLNAISYLHDQGHLHRDIKAGNIL 146
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+D ++K+ DFG++ ++ + + S T++ SS LT GT ++A E++ SH Y
Sbjct: 147 VDSDGSVKLADFGVSASI---YEPVTSSSGTTS-SSLRLTDIAGTPYWMAPEVVHSHTGY 202
Query: 915 NEKVDMYSLGIIFFEMIY---------PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHT 965
K D++S GI E+ + P + + + + K+ D E + KK +
Sbjct: 203 GFKADIWSFGITALELAHGRPPLSHLPPLKSLL--MKITKRFHFSDYEINTSGSSKKGNK 260
Query: 966 E-----KKIIKLLLDHDPVRRPTASALLRSGWVP-VKNQDELIKEALKNISD 1011
+ ++++ L L+ DP +RP+A LL+ + K D ++K L ++S+
Sbjct: 261 KFSKAFREMVGLCLEQDPTKRPSAEKLLKHPFFKNCKGLDFVVKNVLHSLSN 312
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 90.1 bits (222), Expect = 3e-17
Identities = 62/208 (29%), Positives = 104/208 (49%), Gaps = 32/208 (15%)
Query: 793 KSTLFIQMEYCENRTLYDLI----HTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDL 848
K+ ++ ME + L+ + TESL+ + FRQ++ A+ Y H++G+ HRDL
Sbjct: 98 KTKIYFVMELAKGGELFSRVTSNRFTESLSR------KYFRQLISAVRYCHARGVFHRDL 151
Query: 849 KPMNIFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
KP N+ +DE+R++K+ DFGL A QI D G L + GT YVA E+
Sbjct: 152 KPENLLLDENRDLKVSDFGLSAMKEQIHPD-------------GMLHTLCGTPAYVAPEL 198
Query: 908 ITSHGNYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
+ G K D++S G++ F + PF + + +K+ + P D+ L
Sbjct: 199 LLKKGYDGSKADIWSCGVVLFLLNAGYLPF-RDPNIMGLYRKIHKAQYKLP-DWTSSDL- 255
Query: 965 TEKKIIKLLLDHDPVRRPTASALLRSGW 992
+K+++ LL+ +P R T +L+ W
Sbjct: 256 --RKLLRRLLEPNPELRITVEEILKDPW 281
>YDR523c [T] KOG0201 Serine/threonine protein kinase
Length = 490
Score = 89.0 bits (219), Expect = 6e-17
Identities = 67/242 (27%), Positives = 117/242 (47%), Gaps = 31/242 (12%)
Query: 795 TLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKPMNI 853
+++I MEYC + DL+ +N EE + ++ L Y+H Q IHRD+K NI
Sbjct: 88 SMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANI 147
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH-G 912
++E +K+GDFG++ ++ + TL+RD+F +GT ++A E++
Sbjct: 148 LLNEEGMVKLGDFGVSGHI---RSTLKRDTF------------VGTPYWMAPEVVCCEVD 192
Query: 913 NYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
YNEK D++SLGI +E++ + + + +K + N+ P K +
Sbjct: 193 GYNEKADIWSLGITTYELLKGLPP-LSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAG 251
Query: 973 LLDHDPVRRPTASALLRSGWVP------VKNQDELIKEALKNISD-----PSSPWQQQVR 1021
L P RP+A LL +V +K+ +LIK+ K + + P P Q ++
Sbjct: 252 CLVKTPADRPSAYNLLSFEFVKNITITNLKSDVDLIKQ--KKVQERYTKVPKYPLQNRLY 309
Query: 1022 EN 1023
+N
Sbjct: 310 KN 311
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 89.0 bits (219), Expect = 6e-17
Identities = 60/203 (29%), Positives = 100/203 (48%), Gaps = 22/203 (10%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ M+ L+D I + +K+ L RQ+L+A+ Y+H GI+HRDLKP N+
Sbjct: 94 LYLVMQLVSGGELFDRIVEKGFYTEKDAS-TLIRQVLDAVYYLHRMGIVHRDLKPENLLY 152
Query: 856 ---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
DE I I DFGL+K G +++A GT YVA E++ +
Sbjct: 153 YSQDEESKIMISDFGLSK---------------MEGKGDVMSTACGTPGYVAPEVL-AQK 196
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
Y++ VD +S+G+I + ++ YP + +++ + EF S + D + K I
Sbjct: 197 PYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
Query: 971 KLLLDHDPVRRPTASALLRSGWV 993
+ L++ DP +R T R W+
Sbjct: 257 RNLMEKDPNKRYTCEQAARHPWI 279
>Hs15451902 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 894
Score = 89.0 bits (219), Expect = 6e-17
Identities = 69/235 (29%), Positives = 119/235 (50%), Gaps = 38/235 (16%)
Query: 792 RKSTLFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKP 850
R+ L+I ME+C +L D+ H T L+ + Y + R+ L+ L Y+HS+G +HRD+K
Sbjct: 82 RRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAY--VSRETLQGLYYLHSKGKMHRDIKG 139
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI--I 908
NI + ++ ++K+ DFG+ + QI+ +R SF IGT ++A E+ +
Sbjct: 140 ANILLTDNGHVKLADFGV--SAQITATIAKRKSF------------IGTPYWMAPEVAAV 185
Query: 909 TSHGNYNEKVDMYSLGIIFFEM--IYP--FDTGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
G YN+ D++++GI E+ + P FD + +R + + S+F KL
Sbjct: 186 ERKGGYNQLCDLWAVGITAIELAELQPPMFD--------LHPMRALFLMTKSNFQPPKLK 237
Query: 965 TEKK-------IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDP 1012
+ K +K+ L +P +RPTA LL+ +V L E L +++P
Sbjct: 238 DKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNP 292
>Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1558
Score = 88.6 bits (218), Expect = 8e-17
Identities = 62/211 (29%), Positives = 104/211 (48%), Gaps = 17/211 (8%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPM 851
+ ++I MEYC+ TL ++ S +E RL+ +QI A++ +H GI+HRD+K
Sbjct: 1362 REEMYIFMEYCDEGTLEEV----SRLGLQEHVIRLYSKQITIAINVLHEHGIVHRDIKGA 1417
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT-- 909
NIF+ S IK+GDFG + ++ + T+ G++ S +GTA Y+A E+IT
Sbjct: 1418 NIFLTSSGLIKLGDFGCSVKLKNNAQTM----------PGEVNSTLGTAAYMAPEVITRA 1467
Query: 910 SHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+ D++SLG + EM+ E + + + + + ++ K
Sbjct: 1468 KGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPERLSPEGKDF 1527
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDE 1000
+ L+ DP R TAS LL +V V +E
Sbjct: 1528 LSHCLESDPKMRWTASQLLDHSFVKVCTDEE 1558
>Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1607
Score = 88.6 bits (218), Expect = 8e-17
Identities = 62/211 (29%), Positives = 104/211 (48%), Gaps = 17/211 (8%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPM 851
+ ++I MEYC+ TL ++ S +E RL+ +QI A++ +H GI+HRD+K
Sbjct: 1411 REEMYIFMEYCDEGTLEEV----SRLGLQEHVIRLYSKQITIAINVLHEHGIVHRDIKGA 1466
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT-- 909
NIF+ S IK+GDFG + ++ + T+ G++ S +GTA Y+A E+IT
Sbjct: 1467 NIFLTSSGLIKLGDFGCSVKLKNNAQTM----------PGEVNSTLGTAAYMAPEVITRA 1516
Query: 910 SHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+ D++SLG + EM+ E + + + + + ++ K
Sbjct: 1517 KGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPERLSPEGKDF 1576
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDE 1000
+ L+ DP R TAS LL +V V +E
Sbjct: 1577 LSHCLESDPKMRWTASQLLDHSFVKVCTDEE 1607
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 88.6 bits (218), Expect = 8e-17
Identities = 69/228 (30%), Positives = 108/228 (47%), Gaps = 27/228 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS +F ME+ + L+ + R F+Q++ A+ Y HS+GI HRDLKP N
Sbjct: 92 KSKIFFVMEFAKGGELFAKVSKGRFCEDLSR--RYFQQLISAVGYCHSRGIFHRDLKPEN 149
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE ++KI DFGL+ D +R D G L + GT YVA E++ G
Sbjct: 150 LLLDEKLDLKISDFGLS----ALTDQIRPD--------GLLHTLCGTPAYVAPEVLAKKG 197
Query: 913 NYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE--K 967
K+D++S GII F + PF+ N++ R I + +F K + +
Sbjct: 198 YDGAKIDIWSCGIILFVLNAGYLPFNDH----NLMVMYRKI---YKGEFRIPKWTSPDLR 250
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSP 1015
+++ LLD +P R T ++ W D + K L++ SD P
Sbjct: 251 RLLTRLLDTNPQTRITIEEIIHDPWFKQGYDDRMSKFHLED-SDMKLP 297
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 88.6 bits (218), Expect = 8e-17
Identities = 71/237 (29%), Positives = 114/237 (47%), Gaps = 29/237 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ E C L+D + T + +++ + RQI E + YIH++ I+HRDLKP NI +
Sbjct: 103 VFLVFELCPKGELFDYL-TSVVTLSEKKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILL 161
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH---- 911
DE+ N+KI DFG AK +Q + LT+ GT Y+A E + +
Sbjct: 162 DENHNVKITDFGFAKQLQEGE---------------KLTNLCGTPGYLAPETLKCNMFEG 206
Query: 912 -GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI---DVEFPSDFDDKKLHTEK 967
Y+++VD+++ G+I F ++ R ++ LRNI F S K
Sbjct: 207 SPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMV-MLRNIMEGKYSFTSPEWADISEDPK 265
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENL 1024
+I+ L DP +R T +LR P NQ L+ + ++ + P +P Q R L
Sbjct: 266 DLIRKCLVVDPSQRITVKEVLRH---PFFNQMVLMGDR-RHPAPPIAPAQTNSRHLL 318
>CE06427 [J] KOG1936 Histidyl-tRNA synthetase
Length = 520
Score = 88.2 bits (217), Expect = 1e-16
Identities = 95/367 (25%), Positives = 164/367 (43%), Gaps = 46/367 (12%)
Query: 1043 DTTPFLQLLRAQMVDEVIKIFRRHGAIENNEP-----PIIFPKAPIYSTQNVYEVLDRGG 1097
D P LR ++ V + F R+GA + P ++ K + VY++ D+GG
Sbjct: 69 DYGPAQSALRNSVLQTVTETFNRYGAETIDTPVFELRDVLMGKYGEEGGKLVYDLQDQGG 128
Query: 1098 SVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTEPRKFGEVDFDIISNS 1157
+L L+YDLT P ARYL+ N T +Y++ V+R + S R+F + DFDI
Sbjct: 129 ELLSLRYDLTVPFARYLAMNKITNITRYQIAKVYRRDQPVMSRGRYREFYQCDFDIA--G 186
Query: 1158 STDSAVHDAECLKVVDEIVSTFPVFTNTNTILVINHADILDGVFNFCNIDKAQRSLVSHM 1217
D + +AECL +VDE+++ + + +NH IL+G+F I +
Sbjct: 187 QYDLMLPEAECLGIVDELLTKLEI---GEFFINLNHRLILEGMFAVSGIPAKDFKTICSS 243
Query: 1218 LSQLGFGRAFKDLKIDLRSQLNISSTSLNDL-ELFDFR------SDLETSKK--RLSKLL 1268
+ +L ++D++ ++ ++ ++ L EL FR ++LE +K +L L
Sbjct: 244 VDKLD-KTPWEDVEQEMINEKFLTKEQTGKLGELVRFRELNSDLNNLELLEKMSQLPDLG 302
Query: 1269 VDSPYLKRIEEAFGYVSKVVDYFKPLGVTRNVVISPLSNYNNGFYKGGI--------MFQ 1320
+ + K EE + +++Y GVT V P +Y G I +
Sbjct: 303 QNDKFKKGAEE----LKVLIEYLNVDGVT-TVRYEPSLARGLDYYTGAIYEAVAPKALEG 357
Query: 1321 SVFDNGRTRS-------LISAGGRYDNLISLIARPSGGKLNHIQKAVGFNLAWETMFLIV 1373
+ +N + ++AGGRYD L+ + K N V F + E +F I+
Sbjct: 358 TAVENSEDTAGQPVGVGSVAAGGRYDGLVKMF----DSKANVPCCGVSFGI--ERLFAIM 411
Query: 1374 KNYFKLA 1380
+ K+A
Sbjct: 412 EARQKVA 418
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 87.8 bits (216), Expect = 1e-16
Identities = 59/209 (28%), Positives = 104/209 (49%), Gaps = 29/209 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ +E C R+L +L + E + L RQI+ Y+H +IHRDLK N+F+
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYL-RQIVLGCQYLHRNRVIHRDLKLGNLFL 184
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+E +KIGDFGLA V+ + + + GT Y+A E+++ G ++
Sbjct: 185 NEDLEVKIGDFGLATKVEYDGERKK--------------TLCGTPNYIAPEVLSKKG-HS 229
Query: 916 EKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+VD++S+G I + ++ PF+T + ++ +N + P + +I+
Sbjct: 230 FEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKN-EYSIPKHINP----VAASLIQK 284
Query: 973 LLDHDPVRRPTASALLR-----SGWVPVK 996
+L DP RPT + LL SG++P +
Sbjct: 285 MLQTDPTARPTINELLNDEFFTSGYIPAR 313
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 87.8 bits (216), Expect = 1e-16
Identities = 65/207 (31%), Positives = 105/207 (50%), Gaps = 30/207 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
S L++ +E+ ++ H + E + R + QI+ A Y+HS +I+RDLKP N
Sbjct: 123 SNLYMVLEFISGGEMFS--HLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPEN 180
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ ID + +KI DFG AK V+ G + GT Y+A EII S G
Sbjct: 181 LLIDSTGYLKITDFGFAKRVK-----------------GRTWTLCGTPEYLAPEIILSKG 223
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YN+ VD ++LG++ +EM YP + + + +K+ + V+FPS F ++ K ++
Sbjct: 224 -YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNEL----KDLL 278
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKN 997
K LL D +R L++G +KN
Sbjct: 279 KNLLQVDLTKR---YGNLKNGVADIKN 302
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 87.8 bits (216), Expect = 1e-16
Identities = 65/207 (31%), Positives = 105/207 (50%), Gaps = 30/207 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
S L++ +E+ ++ H + E + R + QI+ A Y+HS +I+RDLKP N
Sbjct: 123 SNLYMVLEFISGGEMFS--HLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPEN 180
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ ID + +KI DFG AK V+ G + GT Y+A EII S G
Sbjct: 181 LLIDSTGYLKITDFGFAKRVK-----------------GRTWTLCGTPEYLAPEIILSKG 223
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YN+ VD ++LG++ +EM YP + + + +K+ + V+FPS F ++ K ++
Sbjct: 224 -YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNEL----KDLL 278
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKN 997
K LL D +R L++G +KN
Sbjct: 279 KNLLQVDLTKR---YGNLKNGVADIKN 302
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 87.8 bits (216), Expect = 1e-16
Identities = 61/204 (29%), Positives = 96/204 (46%), Gaps = 24/204 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS ++ ME L+ + L + F+Q++ A+ + HS+G+ HRDLKP N
Sbjct: 94 KSKIYFAMELVRGGELFAKVAKGRLREDVARVY--FQQLISAVDFCHSRGVYHRDLKPEN 151
Query: 853 IFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+ +DE N+K+ DFGL A + QD G L + GT YVA E+I
Sbjct: 152 LLLDEEGNLKVTDFGLSAFTEHLKQD-------------GLLHTTCGTPAYVAPEVILKK 198
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G K D++S G+I F ++ PF VN+ +K+ D + P ++
Sbjct: 199 GYDGAKADLWSCGVILFVLLAGYLPFQDD-NLVNMYRKIYRGDFKCPGWLSS----DARR 253
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
++ LLD +P R T ++ S W
Sbjct: 254 LVTKLLDPNPNTRITIEKVMDSPW 277
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 87.8 bits (216), Expect = 1e-16
Identities = 61/204 (29%), Positives = 106/204 (51%), Gaps = 24/204 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKPM 851
K+ ++ MEY L++ + L KEE R F+Q++ A+++ H++G+ HRDLKP
Sbjct: 96 KAKIYFVMEYVRGGELFNKVAKGRL---KEEVARKYFQQLISAVTFCHARGVYHRDLKPE 152
Query: 852 NIFIDESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
N+ +DE+ N+K+ DFGL A + QI QD G + GT YVA E++
Sbjct: 153 NLLLDENGNLKVSDFGLSAVSDQIRQD-------------GLFHTFCGTPAYVAPEVLAR 199
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMER--VNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G KVD++S G+I F ++ + +R + + KK+ + P F + +
Sbjct: 200 KGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRWFSTEL----TR 255
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
++ LL+ +P +R T ++ + W
Sbjct: 256 LLSKLLETNPEKRFTFPEIMENSW 279
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 87.4 bits (215), Expect = 2e-16
Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 26/203 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ +EYC L+D I ++ ++ EE +FRQI+ A++Y+HSQG HRDLKP N+
Sbjct: 82 IFMVLEYCPGGELFDYIISQDRLSE-EETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLF 140
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
DE +K+ DFGL + ++D L + G+ Y A E+I
Sbjct: 141 DEYHKLKLIDFGLCAKPKGNKDY-------------HLQTCCGSLAYAAPELIQGKSYLG 187
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+ D++S+GI+ + ++ PFD NV+ + I +D K + I+ L
Sbjct: 188 SEADVWSMGILLYVLMCGFLPFDDD----NVMALYKKI---MRGKYDVPKWLSPSSILLL 240
Query: 973 --LLDHDPVRRPTASALLRSGWV 993
+L DP +R + LL W+
Sbjct: 241 QQMLQVDPKKRISMKNLLNHPWI 263
>CE23001 [R] KOG0589 Serine/threonine protein kinase
Length = 579
Score = 87.4 bits (215), Expect = 2e-16
Identities = 61/202 (30%), Positives = 100/202 (49%), Gaps = 24/202 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ L I+MEY + TL ++ +E+ + Q+ A++Y+H ++HRDLK N
Sbjct: 240 EGVLMIEMEYADGGTLAQMLSRTQNLLDEEQIGDMMIQMCSAVAYLHENSVLHRDLKTAN 299
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+F+ +KIGDFG++K + +TL + + T +GT Y++ E + S
Sbjct: 300 VFLTRDSFVKIGDFGISK--IMGTETLAQGAKT----------VVGTPYYISPE-MCSGV 346
Query: 913 NYNEKVDMYSLGIIFFEM-----IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
+YNEK DM++LG I +EM + D VN I V+ P + K
Sbjct: 347 SYNEKSDMWALGCILYEMCCLKKAFEGDNLPALVNSIMTCAYTPVKGPYSAE------MK 400
Query: 968 KIIKLLLDHDPVRRPTASALLR 989
+I+ LL DP +RP+A L+
Sbjct: 401 MVIRELLQLDPQKRPSAPQALK 422
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 87.0 bits (214), Expect = 2e-16
Identities = 76/265 (28%), Positives = 128/265 (47%), Gaps = 37/265 (13%)
Query: 796 LFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+F+ M+Y E L+ L+ ++ N +++ ++ AL Y+HS+ II+RDLKP NI
Sbjct: 160 IFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAA--EVCLALEYLHSKDIIYRDLKPENIL 217
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+D++ +IKI DFG AK V TL GT Y+A E++++ Y
Sbjct: 218 LDKNGHIKITDFGFAKYVPDVTYTL-----------------CGTPDYIAPEVVSTK-PY 259
Query: 915 NEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
N+ +D +S GI+ +EM+ Y + +K+ N ++ FP F++ K ++
Sbjct: 260 NKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNE----DVKDLLSR 315
Query: 973 LLDHDPVRRPTASALLRSGWVPVKNQ---DELIKEAL--KNISDPSSPWQQQVRENLFTQ 1027
L+ D +R L++G VKN E++ E L +NI P P QQ + +
Sbjct: 316 LITRDLSQR---LGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQF 372
Query: 1028 PYHLSSDILFDLSRSDTTPFLQLLR 1052
+ DI + + D P+ L R
Sbjct: 373 DKYPEEDINYGVQGED--PYADLFR 395
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 87.0 bits (214), Expect = 2e-16
Identities = 72/263 (27%), Positives = 124/263 (46%), Gaps = 45/263 (17%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS ++I +E C R+L +L + E + + QI+E + Y+H+ I+HRDLK N
Sbjct: 106 KSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTY-QIVEGVLYLHNLKIVHRDLKLGN 164
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+F+++ +KIGDFGLA T+ + + GT Y+A E++ G
Sbjct: 165 LFLNDELQVKIGDFGLA---------------TTCDNDERKKTLCGTPNYIAPEVLNKIG 209
Query: 913 NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
++ +VD++++G I + +++ PF++ +++N + P+ ++
Sbjct: 210 -HSFEVDLWAIGCILYILLFGHPPFES-KSLEETYSRIKNNNYVIPTSAS----AAASQL 263
Query: 970 IKLLLDHDPVRRPTASALLR-----SGWVPVK------------NQDELIKEAL--KNIS 1010
I++LLD P RRP A A+ R SG++P + N DE +E +
Sbjct: 264 IRVLLDPVPSRRPNARAVCRDHFFKSGFMPARLPVSCLTMVPHLNDDEYAEENVSPSGTI 323
Query: 1011 DPSSPWQQQVRENLFTQPYHLSS 1033
D P Q R L P HL S
Sbjct: 324 DQRGP-HQAGRSGLSAIPAHLVS 345
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 87.0 bits (214), Expect = 2e-16
Identities = 61/203 (30%), Positives = 102/203 (50%), Gaps = 26/203 (12%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +++ MEY ++ L+D I E Q++E F+QI+ + Y H ++HRDLKP N+
Sbjct: 91 SDIYVVMEYVKSGELFDYI-VEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENL 149
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+D NIKI DFGL+ + +R F L ++ G+ Y A E+I+
Sbjct: 150 LLDSRCNIKIADFGLS-------NVMRDGHF--------LKTSCGSPNYAAPEVISGKLY 194
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD++S G+I + ++ PFD E + N+ KK++ PS + + +
Sbjct: 195 AGPEVDVWSCGVILYALLCGTLPFDD--ENIPNLFKKIKGGIYTLPSHLSSE----ARDL 248
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
I +L DPV+R T + + W
Sbjct: 249 IPRMLIVDPVKRITIPEIRQHRW 271
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 87.0 bits (214), Expect = 2e-16
Identities = 61/206 (29%), Positives = 106/206 (50%), Gaps = 27/206 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ ME + L+D I + + +++ L+ + A+ Y+HS I+HRD+KP N+ +
Sbjct: 117 LYLVMELVKGGDLFDAITSTNKYTERDASGMLYN-LASAIKYLHSLNIVHRDIKPENLLV 175
Query: 856 ----DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
D S+++K+GDFGLA V G L + GT YVA EII
Sbjct: 176 YEHQDGSKSLKLGDFGLATIV-----------------DGPLYTVCGTPTYVAPEIIAET 218
Query: 912 GNYNEKVDMYSLGIIFFEMIYPF----DTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
G Y KVD+++ G+I + ++ F +G ++ + ++ V+FPS + D + K
Sbjct: 219 G-YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 277
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
++I ++L D +R +A +L WV
Sbjct: 278 ELITMMLLVDVDQRFSAVQVLEHPWV 303
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 86.7 bits (213), Expect = 3e-16
Identities = 62/198 (31%), Positives = 101/198 (50%), Gaps = 22/198 (11%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ +EY E L++L+ E + E R FRQI+ +SY H+ GI+HRDLKP N+ +
Sbjct: 106 LYLVLEYAEKGELFNLL-VERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLL 164
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D NIKI DFG+A + + G L ++ G+ Y A EI++
Sbjct: 165 DHKYNIKIADFGMA-------------ALETEGKL--LETSCGSPHYAAPEIVSGIPYQG 209
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
D++S G+I F ++ PFD + ++ K++ + E PS DD+ + +I+
Sbjct: 210 FASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPS--DDEISREAQDLIR 267
Query: 972 LLLDHDPVRRPTASALLR 989
+L DP RR +L+
Sbjct: 268 KILTVDPERRIKTRDILK 285
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 86.7 bits (213), Expect = 3e-16
Identities = 83/321 (25%), Positives = 142/321 (43%), Gaps = 49/321 (15%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K + + +EY N ++ + ++ Q+ R F+QI+ A+ Y H I+HRDLKP N
Sbjct: 125 KDEIIMVIEYAGNELFDYIVQRDKMSEQEAR--RFFQQIISAVEYCHRHKIVHRDLKPEN 182
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE N+KI DFGL+ N+ + L+ TS GS Y A E+I+
Sbjct: 183 LLLDEHLNVKIADFGLS-NIMTDGNFLK----TSCGSPN----------YAAPEVISGKL 227
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVI-KKLRNIDVEFPSDFDDKKLHTEKK 968
+VD++S G+I + M+ PFD E + V+ K + N P
Sbjct: 228 YAGPEVDVWSCGVILYVMLCRRLPFDD--ESIPVLFKNISNGVYTLPKFLSP----GAAG 281
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALK-----------NISDPSSPWQ 1017
+IK +L +P+ R + +++ W V + L+ LK + D SSP
Sbjct: 282 LIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEENENNDSKKDGSSPDN 341
Query: 1018 QQVRENLF-----TQPYHLSSDILFDLSRSDTTP-FLQLLRAQMV----DEVIKIFRRHG 1067
++ +NL T Y +I L S+ TP F ++ A M+ +IK + +
Sbjct: 342 DEIDDNLVNILSSTMGYE-KDEIYESLESSEDTPAFNEIRDAYMLIKENKSLIKDMKANK 400
Query: 1068 AIENNEPPIIFPKAPIYSTQN 1088
++ + + P + Q+
Sbjct: 401 SVSDELDTFLSQSPPTFQQQS 421
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 86.7 bits (213), Expect = 3e-16
Identities = 61/226 (26%), Positives = 109/226 (47%), Gaps = 32/226 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ +EY ++D + +KE + FRQI+ A+ Y+HS+ IIHRDLK N
Sbjct: 191 EQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYLHSKNIIHRDLKAEN 249
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D+ NIKI DFG + + + D+F G+ Y A E+ +
Sbjct: 250 LLLDQDMNIKIADFGFSNTFSLGN---KLDTF------------CGSPPYAAPELFSGKK 294
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 295 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 348
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
++K L +P RR + +++ W+ V +D+ +K ++ D
Sbjct: 349 ---LLKKFLVINPQRRSSLDNIMKDRWMNVGYEDDELKPFIEPPKD 391
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 86.7 bits (213), Expect = 3e-16
Identities = 61/226 (26%), Positives = 109/226 (47%), Gaps = 32/226 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ +EY ++D + +KE + FRQI+ A+ Y+HS+ IIHRDLK N
Sbjct: 239 EQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYLHSKNIIHRDLKAEN 297
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D+ NIKI DFG + + + D+F G+ Y A E+ +
Sbjct: 298 LLLDQDMNIKIADFGFSNTFSLGN---KLDTF------------CGSPPYAAPELFSGKK 342
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 343 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 396
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
++K L +P RR + +++ W+ V +D+ +K ++ D
Sbjct: 397 ---LLKKFLVINPQRRSSLDNIMKDRWMNVGYEDDELKPFIEPPKD 439
>YHR079c [T] KOG1027 Serine/threonine protein kinase and endoribonuclease
ERN1/IRE1 sensor of the unfolded protein response pathway
Length = 1115
Score = 85.9 bits (211), Expect = 5e-16
Identities = 72/269 (26%), Positives = 128/269 (46%), Gaps = 52/269 (19%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQ----KEEY--WRLFRQILEALSYIHSQGIIHRDLK 849
L+I +E C N L DL+ +++++++ ++EY L RQI ++++HS IIHRDLK
Sbjct: 741 LYIALELC-NLNLQDLVESKNVSDENLKLQKEYNPISLLRQIASGVAHLHSLKIIHRDLK 799
Query: 850 PMNIFID-------------ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSG----- 891
P NI + E+ I I DFGL K + Q + R + +G+SG
Sbjct: 800 PQNILVSTSSRFTADQQTGAENLRILISDFGLCKKLDSGQSSFRTNLNNPSGTSGWRAPE 859
Query: 892 ------DLTSAIGTALYVASEIITSHGNY---------NEKVDMYSLGIIFFEMI----Y 932
+L + T + + S ++ +D++S+G +F+ ++ +
Sbjct: 860 LLEESNNLQCQVETEHSSSRHTVVSSDSFYDPFTKRRLTRSIDIFSMGCVFYYILSKGKH 919
Query: 933 PF-DTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSG 991
PF D N+I+ + ++D E D + +I ++DHDP++RPTA +LR
Sbjct: 920 PFGDKYSRESNIIRGIFSLD-EMKCLHDRSLIAEATDLISQMIDHDPLKRPTAMKVLRHP 978
Query: 992 --WVPVKNQDELIKEA----LKNISDPSS 1014
W K + L+K + ++N PS+
Sbjct: 979 LFWPKSKKLEFLLKVSDRLEIENRDPPSA 1007
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 85.9 bits (211), Expect = 5e-16
Identities = 72/248 (29%), Positives = 117/248 (47%), Gaps = 16/248 (6%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPM 851
K L++ MEYC + + T EE + + +++ AL Y+H G I+RDLKP
Sbjct: 394 KDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPE 453
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSF---TSAGSSGDLT-SAIGTALYVASEI 907
NI + +S ++ + DF L+ S+ +DS T S G T S +GT Y+A E+
Sbjct: 454 NILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEV 513
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
I +G + VD ++LGI+ +EM++ PF G + DV+FP D + K
Sbjct: 514 IRGNG-HTAAVDWWTLGILIYEMLFGCTPF-KGDNSNETFSNILTKDVKFPHDKEVSK-- 569
Query: 965 TEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENL 1024
K +IK LL+ + +R + +SG +K K + + P + +N
Sbjct: 570 NCKDLIKKLLNKNEAKRLGS----KSGAADIKRHPFFKKVQWSFLRNQDPPLIPALNDNG 625
Query: 1025 FTQPYHLS 1032
P+ LS
Sbjct: 626 CELPFILS 633
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 85.9 bits (211), Expect = 5e-16
Identities = 66/209 (31%), Positives = 107/209 (50%), Gaps = 32/209 (15%)
Query: 796 LFIQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
LFI MEY E L D LI S++ Q + L +Q+LE L ++H QG+ HRD+KP NI
Sbjct: 244 LFIVMEYVEGGDLMDFLIANGSIDEQ--DCKPLLKQLLETLLHLHKQGVTHRDIKPENIL 301
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS---- 910
I ++KI DFGLAK + G+ L + GT Y+A E++ S
Sbjct: 302 ITNDFHLKISDFGLAKVIH--------------GTGTFLETFCGTMGYLAPEVLKSKNVN 347
Query: 911 -HGNYNEKVDMYSLGIIFFEMI---YPFDTGMER--VNVIKK-LRNIDVEFPSDFDDKKL 963
G Y++KVD++SLG + + M+ PF + + + +I K I+ ++ ++ +
Sbjct: 348 LDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGI 407
Query: 964 HTEKKIIKLLLDHDPVRRPTASALLRSGW 992
+I +L+ +P +R + S L+ W
Sbjct: 408 ----DLINRMLEINPEKRISESEALQHPW 432
>CE06762 [T] KOG0660 Mitogen-activated protein kinase
Length = 367
Score = 85.9 bits (211), Expect = 5e-16
Identities = 52/137 (37%), Positives = 81/137 (58%), Gaps = 9/137 (6%)
Query: 796 LFIQMEYCENRTLYDLIHT-ESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+++ M+ E L+ ++H+ ++L Q +Y+ F Q+L L Y+HS GIIHRDLKP N+
Sbjct: 133 IYLVMDLMET-DLHQILHSRQTLMEQHFQYF--FYQLLRGLKYLHSAGIIHRDLKPSNLL 189
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
++ ++I DFG+A+ S T+R D A G +T + T Y A EI+ S Y
Sbjct: 190 LNGDCLLRIADFGMAR-AYASASTVRDD----ANVGGHMTQYVSTRWYRAPEILFSMVEY 244
Query: 915 NEKVDMYSLGIIFFEMI 931
+ KVD++S G IF EM+
Sbjct: 245 DTKVDLWSAGCIFAEML 261
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 85.9 bits (211), Expect = 5e-16
Identities = 71/265 (26%), Positives = 124/265 (46%), Gaps = 36/265 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ ++I MEY LY+ + L R F+Q++ ++++ HS+G+ HRDLK N
Sbjct: 127 KTKIYIVMEYVRGGELYNTVARGRLREGTAR--RYFQQLISSVAFCHSRGVYHRDLKLEN 184
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D+ N+K+ DFGL+ + + L+++ G + GT Y+A E++T G
Sbjct: 185 LLLDDKGNVKVSDFGLS----VVSEQLKQE--------GICQTFCGTPAYLAPEVLTRKG 232
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
K D++S G+I F ++ PFD V + K+ + P F + ++
Sbjct: 233 YEGAKADIWSCGVILFVLMAGYLPFDDKNILV-MYTKIYKGQFKCPKWFSPEL----ARL 287
Query: 970 IKLLLDHDPVRRPTASALLRSGWVP-----VK---NQDELIKEALKNISDPSSPWQQQVR 1021
+ +LD +P R T +++ W VK D+L +E N D SS R
Sbjct: 288 VTRMLDTNPDTRITIPEIMKHRWFKKGFKHVKFYIENDKLCREDDDNDDDDSSSLSSG-R 346
Query: 1022 ENLFTQPYHLSSDILFDLSRSDTTP 1046
+ ++ D FD+ R D+ P
Sbjct: 347 SSTASE-----GDAEFDIKRVDSMP 366
>SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 362
Score = 85.5 bits (210), Expect = 7e-16
Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 16/168 (9%)
Query: 829 RQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAG 888
+Q L+ L Y+HS+GI+HRD+K NI +D IKI DFG++K ++++ TS
Sbjct: 207 KQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNS--------TSTK 258
Query: 889 SSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIK 945
+ G S G++ ++A E++ + EK D++SLG + EM+ +P+ + + +
Sbjct: 259 TGGARPSFQGSSFWMAPEVV-KQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFR 317
Query: 946 KLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWV 993
NI EFPS+ + +K + D RPTAS LL +V
Sbjct: 318 IGENILPEFPSNISSSAIDFLEKTFAI----DCNLRPTASELLSHPFV 361
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 85.5 bits (210), Expect = 7e-16
Identities = 62/204 (30%), Positives = 100/204 (48%), Gaps = 25/204 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
++ ++I +EY L+D I ++ E + F Q+++ + Y HS+G+ HRDLKP N
Sbjct: 79 RTKIYIILEYITGGELFDKIVRNGRLSESEAR-KYFHQLIDGVDYCHSKGVYHRDLKPEN 137
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D N+KI DFGL+ L T L + GT YVA E++ SH
Sbjct: 138 LLLDSQGNLKISDFGLS--------ALPEQGVTI------LKTTCGTPNYVAPEVL-SHK 182
Query: 913 NYNEKV-DMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
YN V D++S G+I + ++ PFD M+ + K+ + PS F K
Sbjct: 183 GYNGAVADIWSCGVILYVLMAGYLPFDE-MDLPTLYSKIDKAEFSCPSYF----ALGAKS 237
Query: 969 IIKLLLDHDPVRRPTASALLRSGW 992
+I +LD +P R T + + + W
Sbjct: 238 LINRILDPNPETRITIAEIRKDEW 261
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 85.5 bits (210), Expect = 7e-16
Identities = 64/216 (29%), Positives = 104/216 (47%), Gaps = 32/216 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L++ +E+ L+D + + KE + FRQI+ AL + HS I HRDLKP N
Sbjct: 87 KKYLYLILEHVSGGELFDYLVKKGRLTPKEAR-KFFRQIISALDFCHSHSICHRDLKPEN 145
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE NIKI DFG+A S AGS L ++ G+ Y E+I
Sbjct: 146 LLLDEKNNIKIADFGMA-------------SLQPAGSM--LETSCGSPHYACPEVIRGEK 190
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLR----NIDVEFPSDFDDKKLHT 965
K D++S G+I + ++ PFD R +++K++ +I P D
Sbjct: 191 YDGRKADVWSCGVILYALLVGALPFDDDNLR-QLLEKVKRGVFHIPHFVPPDC------- 242
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDEL 1001
+ +++ +++ +P RR T + + R WV + EL
Sbjct: 243 -QSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGEL 277
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 85.1 bits (209), Expect = 9e-16
Identities = 62/230 (26%), Positives = 108/230 (46%), Gaps = 32/230 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + +KE + FRQI+ A+ Y H + I+HRDLK N
Sbjct: 89 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKFIVHRDLKAEN 147
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + FT L + G+ Y A E+
Sbjct: 148 LLLDADMNIKIADFGFS------------NEFTFGNK---LDTFCGSPPYAAPELFQGKK 192
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 193 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 246
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSP 1015
++K L +P +R T +++ W+ V ++D+ +K ++ + D P
Sbjct: 247 ---LLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDP 293
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 85.1 bits (209), Expect = 9e-16
Identities = 62/230 (26%), Positives = 108/230 (46%), Gaps = 32/230 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + +KE + FRQI+ A+ Y H + I+HRDLK N
Sbjct: 89 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKFIVHRDLKAEN 147
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + FT L + G+ Y A E+
Sbjct: 148 LLLDADMNIKIADFGFS------------NEFTFGNK---LDTFCGSPPYAAPELFQGKK 192
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 193 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 246
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSP 1015
++K L +P +R T +++ W+ V ++D+ +K ++ + D P
Sbjct: 247 ---LLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDP 293
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 85.1 bits (209), Expect = 9e-16
Identities = 57/200 (28%), Positives = 98/200 (48%), Gaps = 24/200 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K ++I +EYC R++ ++ + + E + L RQI+ L Y+H Q I+HRDLK N
Sbjct: 152 KENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL-RQIVSGLKYLHEQEILHRDLKLGN 210
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
FI+E+ +K+GDFGLA ++ + R + GT Y++ E++ G
Sbjct: 211 FFINEAMELKVGDFGLAARLEPLEHRRR--------------TICGTPNYLSPEVLNKQG 256
Query: 913 NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+ E D+++LG + + M+ PF+T + +R PS L K +
Sbjct: 257 HGCES-DIWALGCVMYTMLLGRPPFET-TNLKETYRCIREARYTMPSSL----LAPAKHL 310
Query: 970 IKLLLDHDPVRRPTASALLR 989
I +L +P RP+ ++R
Sbjct: 311 IASMLSKNPEDRPSLDDIIR 330
>Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase
Length = 968
Score = 85.1 bits (209), Expect = 9e-16
Identities = 83/312 (26%), Positives = 140/312 (44%), Gaps = 47/312 (15%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L+I +E+C + ++ + + + RQ+LEAL+++HS+ IIHRDLK N+ +
Sbjct: 106 LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLM 165
Query: 856 DESRNIKIGDFGL-AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEII----TS 910
+I++ DFG+ AKN++ Q +RDSF IGT ++A E++
Sbjct: 166 TLEGDIRLADFGVSAKNLKTLQ---KRDSF------------IGTPYWMAPEVVMCETMK 210
Query: 911 HGNYNEKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE-K 967
Y+ K D++SLGI EM I P + + V+ K+ D P+ K E +
Sbjct: 211 DTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDP--PTLLTPSKWSVEFR 268
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPV----KNQDELIKEALKNIS------------- 1010
+K+ LD +P RP+A+ LL +V K EL+ EA +
Sbjct: 269 DFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEEIEDGRDEGEEE 328
Query: 1011 ---DPSSPWQQQVRENLFTQPYHLSSDILFDLSRSDTTPFLQLLRAQMVDEVIKIFRRHG 1067
D +S + + + P L++D L S +TP V+E
Sbjct: 329 DAVDAASTLENHTQNSSEVSPPSLNAD--KPLEESPSTPLAPSQSQDSVNEPCSQPSGDR 386
Query: 1068 AIENNEPPIIFP 1079
+++ PP++ P
Sbjct: 387 SLQTTSPPVVAP 398
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 85.1 bits (209), Expect = 9e-16
Identities = 56/203 (27%), Positives = 102/203 (49%), Gaps = 23/203 (11%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +F+ + L+D + TE + ++E + R +LEA+S++H+ I+HRDLKP NI
Sbjct: 101 SFMFLVFDLMRKGELFDYL-TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENI 159
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEII----- 908
+D++ I++ DFG + +++ + L GT Y+A EI+
Sbjct: 160 LLDDNMQIRLSDFGFSCHLEPGE---------------KLRELCGTPGYLAPEILKCSMD 204
Query: 909 TSHGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
+H Y ++VD+++ G+I F ++ P ++ +++ + +F S D + T
Sbjct: 205 ETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTV 264
Query: 967 KKIIKLLLDHDPVRRPTASALLR 989
K +I LL DP R TA L+
Sbjct: 265 KDLISRLLQVDPEARLTAEQALQ 287
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 85.1 bits (209), Expect = 9e-16
Identities = 62/230 (26%), Positives = 108/230 (46%), Gaps = 32/230 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + +KE + FRQI+ A+ Y H + I+HRDLK N
Sbjct: 122 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKFIVHRDLKAEN 180
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + FT L + G+ Y A E+
Sbjct: 181 LLLDADMNIKIADFGFS------------NEFTFGNK---LDTFCGSPPYAAPELFQGKK 225
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 226 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 279
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSP 1015
++K L +P +R T +++ W+ V ++D+ +K ++ + D P
Sbjct: 280 ---LLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDP 326
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 576
Score = 85.1 bits (209), Expect = 9e-16
Identities = 68/227 (29%), Positives = 110/227 (47%), Gaps = 29/227 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+++ +EY + L+D I ES+ + + + + +AL ++H + I+HRDLKP N+ +
Sbjct: 355 IYLILEYVQGGDLFDAI-IESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLV 413
Query: 856 ----DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
D+S +K+ DFGLAK+V R FT GT YVA EI++
Sbjct: 414 QRNEDKSTTLKLADFGLAKHVV-------RPIFT----------VCGTPTYVAPEILSEK 456
Query: 912 GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI----DVEFPSDFDDKKLHTEK 967
G Y +VDM++ G+I + ++ F +L NI EF + D K
Sbjct: 457 G-YGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAK 515
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSS 1014
++ LL DP +R TA +L+ W+ + +K K +S PSS
Sbjct: 516 DLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQ-KQVS-PSS 560
>Hs14589909 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 846
Score = 85.1 bits (209), Expect = 9e-16
Identities = 68/237 (28%), Positives = 119/237 (49%), Gaps = 39/237 (16%)
Query: 793 KSTLFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
+ L+I MEYC +L D+ H T L+ + Y + R+ L+ L+Y+H++G +HRD+K
Sbjct: 87 REKLWICMEYCGGGSLQDIYHVTGPLSELQIAY--VCRETLQGLAYLHTKGKMHRDIKGA 144
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI--IT 909
NI + + ++K+ DFG+A +I+ +R SF IGT ++A E+ +
Sbjct: 145 NILLTDHGDVKLADFGVA--AKITATIAKRKSF------------IGTPYWMAPEVAAVE 190
Query: 910 SHGNYNEKVDMYSLGIIFFEM--IYP--FDTGMERVNVIKKLRNIDVEFPSDFDDKKLHT 965
+G YN+ D++++GI E+ + P FD + +R + + S+F KL
Sbjct: 191 KNGGYNQLCDIWAVGITAIELGELQPPMFD--------LHPMRALFLMSKSNFQPPKLKD 242
Query: 966 EKK-------IIKLLLDHDPVRRPTASALLRSGWVPVKNQDE-LIKEALKNISDPSS 1014
+ K +K+ L +P +RPTA LL +V L E L +++P +
Sbjct: 243 KTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDN 299
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 85.1 bits (209), Expect = 9e-16
Identities = 76/248 (30%), Positives = 118/248 (46%), Gaps = 34/248 (13%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +F+ ME+ L+D I + E R F+QI+ + Y H ++HRDLKP N+
Sbjct: 96 SDIFMIMEHVSGGELFDYIVKHG-RLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENL 154
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+DE N+KI DFGL+ N+ D LR TS GS Y A E+I+
Sbjct: 155 LLDEQNNVKIADFGLS-NIMTDGDFLR----TSCGSPN----------YAAPEVISGKLY 199
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD++S G+I + ++ PFD E V ++ +K+++ P DF E+ I
Sbjct: 200 AGPEVDVWSCGVILYALLCGTLPFDD--EHVPSLFRKIKSGVFPTP-DF------LERPI 250
Query: 970 IKLL---LDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFT 1026
+ LL L DP++R T ++ W + L N S+ S + VRE
Sbjct: 251 VNLLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFPPI--NESEASIVDIEAVREVTEF 308
Query: 1027 QPYHLSSD 1034
Q YH++ +
Sbjct: 309 QRYHVAEE 316
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 85.1 bits (209), Expect = 9e-16
Identities = 61/235 (25%), Positives = 114/235 (47%), Gaps = 14/235 (5%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K +F MEY L+++I + ++ + F+Q++ A+ + HS+G+ HRD+KP N
Sbjct: 86 KKKIFFVMEYVNGGELFEMIDRDG-KLPEDLARKYFQQLISAVDFCHSRGVFHRDIKPEN 144
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLT-SAIGTALYVASEIITSH 911
+ +D ++K+ DFGL+ + RR GSS DL + GT YVA E++ +
Sbjct: 145 LLLDGEGDLKVTDFGLSALMMPEGLGGRR------GSSDDLLHTRCGTPAYVAPEVLRNK 198
Query: 912 GNYNEKVDMYSLGIIFFEMIYPFDTGMER--VNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
G D++S GI+ + ++ F ++ + + K+ + EFP F + K++
Sbjct: 199 GYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLE----SKEL 254
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENL 1024
+ LL DP +R + S + W + + I P P ++ +++L
Sbjct: 255 LSRLLVPDPEQRISMSEIKMIPWFRKNFTPSVAFSIDETIPSPPEPPTKKKKKDL 309
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 84.7 bits (208), Expect = 1e-15
Identities = 76/306 (24%), Positives = 136/306 (43%), Gaps = 50/306 (16%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L++ +E+ L+D + + KE + FRQI+ AL + H+ I HRDLKP N
Sbjct: 116 KKYLYLLLEHVSGGELFDYLVRKGRLMSKEAR-KFFRQIISALDFCHAHNICHRDLKPEN 174
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE NIK+ DFG+A S GS L ++ G+ Y E+I
Sbjct: 175 LLLDERNNIKVADFGMA-------------SLQVEGSM--LETSCGSPHYACPEVIRGEK 219
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLR----NIDVEFPSDFDDKKLHT 965
K D++S G+I + ++ PFD R N+++K++ +I P+D
Sbjct: 220 YDGRKADVWSCGVILYALLVGALPFDDDNLR-NLLEKVKRGVFHIPHFVPADV------- 271
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWV--PVKNQDELIKEALKNISDPSSPWQQQVREN 1023
+ +++ +++ DP +R + + + + WV K EL + + P + + +
Sbjct: 272 -QSLLRAMIEVDPGKRYSLADVFKHPWVSGTTKADPELELPMSQVVQTHVIPGEDSIDPD 330
Query: 1024 L---------FTQPYHLSSDILFDLSRSDTTPFLQLL-----RAQMVDEVIKIFRRHGAI 1069
+ F L +++L ++ + LL R D+ + R GA
Sbjct: 331 VLRHMNCLGCFKDKQKLINELLSPKHNTEKMVYFLLLDRKRRRPAQEDDTEIVLR--GAA 388
Query: 1070 ENNEPP 1075
+NN+PP
Sbjct: 389 QNNDPP 394
>At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 546
Score = 84.7 bits (208), Expect = 1e-15
Identities = 60/198 (30%), Positives = 101/198 (50%), Gaps = 30/198 (15%)
Query: 792 RKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
R TL I E+ ++YD +H + + + ++ + + +SY+H IIHRDLK
Sbjct: 352 RSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTA 411
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
N+ +DE +K+ DFG+A+ VQI SG +T+ GT ++A E+I H
Sbjct: 412 NLLMDEHGLVKVADFGVAR-VQI--------------ESGVMTAETGTYRWMAPEVI-EH 455
Query: 912 GNYNEKVDMYSLGIIFFEMI-----YPFDTGME-RVNVIKKLRNIDVEFPSDFDDKKLHT 965
YN K D++S I+ +E++ Y F T ++ V V++K + + P KK H
Sbjct: 456 KPYNHKADVFSYAIVLWELLTGDIPYAFLTPLQAAVGVVQK--GLRPKIP-----KKTHP 508
Query: 966 E-KKIIKLLLDHDPVRRP 982
+ K +++ DP +RP
Sbjct: 509 KVKGLLERCWHQDPEQRP 526
>7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 979
Score = 84.7 bits (208), Expect = 1e-15
Identities = 70/241 (29%), Positives = 118/241 (48%), Gaps = 27/241 (11%)
Query: 789 KSP--RKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIH 845
KSP + L++ MEYC ++ DL+ + + KEE+ + R+IL LSY+HS +IH
Sbjct: 99 KSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNKVIH 158
Query: 846 RDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVAS 905
RD+K N+ + ++ +K+ DFG+ + Q+ + RR++F IGT ++A
Sbjct: 159 RDIKGQNVLLTDNAEVKLVDFGV--SAQLDRTIGRRNTF------------IGTPYWMAP 204
Query: 906 EIITSHGN----YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKL-RNIDVEFPSDF 958
E+I N Y+ + D++SLGI EM P + + + + RN S
Sbjct: 205 EVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKSKK 264
Query: 959 DDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQ 1018
KK H I +L D +RP LL+ G++ + D ++ LK+ D +Q
Sbjct: 265 WSKKFH---GFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDRCKKRKQ 321
Query: 1019 Q 1019
+
Sbjct: 322 E 322
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 84.3 bits (207), Expect = 1e-15
Identities = 57/218 (26%), Positives = 102/218 (46%), Gaps = 32/218 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + +KE + FRQI+ A+ Y H + I+HRDLK N
Sbjct: 125 QKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSK-FRQIVSAVQYCHQKRIVHRDLKAEN 183
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + G L + G+ Y A E+
Sbjct: 184 LLLDADMNIKIADFGFSNEFTV---------------GGKLDTFCGSPPYAAPELFQGKK 228
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 229 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 282
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIK 1003
++K L +P++R T +++ W+ ++++ +K
Sbjct: 283 ---LLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELK 317
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 84.3 bits (207), Expect = 1e-15
Identities = 62/206 (30%), Positives = 100/206 (48%), Gaps = 27/206 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
LF+ ME + L+D I T S + + + + AL Y+H I+HRD+KP N+ +
Sbjct: 287 LFLVMELVKGGDLFDAI-TSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLV 345
Query: 856 ----DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
D ++++K+GDFGLA V+ G L + GT YVA EII
Sbjct: 346 CEYPDGTKSLKLGDFGLATVVE-----------------GPLYTVCGTPTYVAPEIIAET 388
Query: 912 GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI----DVEFPSDFDDKKLHTEK 967
G Y KVD+++ G+I + ++ F N+ + L + +EFP+ + D + K
Sbjct: 389 G-YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAK 447
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
++I +L + R TA +L WV
Sbjct: 448 ELISQMLQVNVEARCTAGQILSHPWV 473
>Hs22035600 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 820
Score = 84.3 bits (207), Expect = 1e-15
Identities = 65/228 (28%), Positives = 112/228 (48%), Gaps = 24/228 (10%)
Query: 792 RKSTLFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKP 850
R L+I ME+C +L ++ H T L ++ Y + R+ L+ L ++HSQG IHRD+K
Sbjct: 82 RNDRLWICMEFCGGGSLQEIYHATGPLEERQIAY--VCREALKGLHHLHSQGKIHRDIKG 139
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI--I 908
N+ + ++K+ DFG++ +++ +R SF IGT ++A E+ +
Sbjct: 140 ANLLLTLQGDVKLADFGVSG--ELTASVAKRRSF------------IGTPYWMAPEVAAV 185
Query: 909 TSHGNYNEKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
G YNE D+++LGI E+ + P + + + + + P DK T+
Sbjct: 186 ERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQ-PPKLRDKTRWTQ 244
Query: 967 K--KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDP 1012
+KL L +P +RPTA LL+ + + L+ + L SDP
Sbjct: 245 NFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDP 292
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 84.0 bits (206), Expect = 2e-15
Identities = 63/208 (30%), Positives = 106/208 (50%), Gaps = 23/208 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K +I + + L+D I + + E+ R+ +IL A+ Y+HSQ I+HRDLKP N
Sbjct: 108 KDKFYIITQLAKGGELFDRILKKGKFTE-EDAVRILVEILSAVKYMHSQNIVHRDLKPEN 166
Query: 853 -IFIDESRN--IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
++ID+S + + DFG+AK ++ ++ L + AGS G YVA E++T
Sbjct: 167 LLYIDKSDESPLVVADFGIAKRLKSDEELL----YKPAGSLG----------YVAPEVLT 212
Query: 910 SHGNYNEKVDMYSLGIIFFEMIYPFDT-GMERVNVIK---KLRNIDVEFPSDFDDKKLHT 965
G + + D++S+G+I + ++ + ERV V+F + D +
Sbjct: 213 QDG-HGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNK 271
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWV 993
K+ I L+ DP +RPTA+ LL W+
Sbjct: 272 AKQFILKALNLDPSKRPTAAELLEDPWI 299
>SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1401
Score = 84.0 bits (206), Expect = 2e-15
Identities = 65/206 (31%), Positives = 105/206 (50%), Gaps = 12/206 (5%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPM 851
+ ++I ME+C+ +L DL+ + + E +++ Q+LE L+YIHSQ I+HRD+KP
Sbjct: 1108 REKVYIFMEFCQGGSLADLLAHGRIED--ENVLKVYVVQLLEGLAYIHSQHILHRDIKPA 1165
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEII--T 909
NI +D IK DFG A V D R +L GT +Y+A EII T
Sbjct: 1166 NILLDHRGMIKYSDFGSALYVSPPTDPEVR----YEDIQPELQHLAGTPMYMAPEIILGT 1221
Query: 910 SHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI-DVEFPSDFDDKKLHT-EK 967
G++ +D++SLG + EM+ E N + ++ + PS ++K+ + +
Sbjct: 1222 KKGDFG-AMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNEKISSLAR 1280
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
I+ + DP +RP A LL W+
Sbjct: 1281 DFIEQCFERDPEQRPRAVDLLTHPWI 1306
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 84.0 bits (206), Expect = 2e-15
Identities = 59/218 (27%), Positives = 105/218 (48%), Gaps = 32/218 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + +KE + FRQI+ A+ Y H + I+HRDLK N
Sbjct: 129 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK-FRQIVSAVQYCHQKYIVHRDLKAEN 187
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + + D+F G+ Y A E+
Sbjct: 188 LLLDGDMNIKIADFGFSNEFTVGN---KLDTF------------CGSPPYAAPELFQGKK 232
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGME----RVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLG+I + ++ PFD G R V++ I +D ++
Sbjct: 233 YDGPEVDVWSLGVILYTLVSGSLPFD-GQNLKELRERVLRGKYRIPFYMSTDCEN----- 286
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIK 1003
++K LL +P++R + +++ W+ V +++E +K
Sbjct: 287 ---LLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELK 321
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 84.0 bits (206), Expect = 2e-15
Identities = 64/207 (30%), Positives = 101/207 (47%), Gaps = 30/207 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
S L++ MEY ++ H + E + R + QI+ Y+HS +I+RDLKP N
Sbjct: 115 SNLYMVMEYVPGGEMFS--HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPEN 172
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ ID+ I++ DFG AK V+ G + GT Y+A EII S G
Sbjct: 173 LLIDQQGYIQVTDFGFAKRVK-----------------GRTWTLCGTPEYLAPEIILSKG 215
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YN+ VD ++LG++ +EM YP + + + +K+ + V FPS F K ++
Sbjct: 216 -YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL----KDLL 270
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKN 997
+ LL D +R L++G +KN
Sbjct: 271 RNLLQVDLTKR---FGNLKNGVNDIKN 294
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 84.0 bits (206), Expect = 2e-15
Identities = 56/181 (30%), Positives = 94/181 (50%), Gaps = 20/181 (11%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMNIF 854
L+ + Y +N L L + + + E R + +I+ AL Y+H +GIIHRDLKP NI
Sbjct: 155 LYFGLSYAKNGEL--LKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENIL 212
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
++E +I+I DFG AK + R +SF +GTA YV+ E++T
Sbjct: 213 LNEDMHIQITDFGTAKVLSPESKQARANSF------------VGTAQYVSPELLTEKSAC 260
Query: 915 NEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
D+++LG I ++++ PF G E + + +K+ ++ +FP F K +K++
Sbjct: 261 KSS-DLWALGCIIYQLVAGLPPFRAGNEYL-IFQKIIKLEYDFPEKFFPKARDLVEKLLV 318
Query: 972 L 972
L
Sbjct: 319 L 319
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 84.0 bits (206), Expect = 2e-15
Identities = 60/206 (29%), Positives = 98/206 (47%), Gaps = 23/206 (11%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K +++ ME L+D I + +++ L RQ+LEA+ ++H G++HRDLKP N
Sbjct: 91 KQFVYLVMELVTGGELFDRIVAKGSYTEQDAS-NLIRQVLEAVGFMHDNGVVHRDLKPEN 149
Query: 853 IFI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
+ DE I I DFGL+K SG + +A GT YVA E++
Sbjct: 150 LLYYNQDEDSKIMISDFGLSK----------------TEDSGVMATACGTPGYVAPEVL- 192
Query: 910 SHGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
Y + VD++S+G+I + ++ YP N+ ++ + EF + + D+ + K
Sbjct: 193 QQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAK 252
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
I L+ DP R T L W+
Sbjct: 253 DFITHLMCCDPEARFTCQDALSHPWI 278
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 84.0 bits (206), Expect = 2e-15
Identities = 76/248 (30%), Positives = 119/248 (47%), Gaps = 36/248 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +F+ ME+ L+D I + E R F+QI+ + Y H ++HRDLKP N+
Sbjct: 96 SDIFMIMEHVSGGELFDYIVKHG-RLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENL 154
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+DE N+KI DFGL+ N+ D LR TS GS Y A E+I+
Sbjct: 155 LLDEQNNVKIADFGLS-NIMTDGDFLR----TSCGSPN----------YAAPEVISGKLY 199
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD++S G+I + ++ PFD E V ++ +K+++ P DF E+ I
Sbjct: 200 AGPEVDVWSCGVILYALLCGTLPFDD--EHVPSLFRKIKSGVFPTP-DF------LERPI 250
Query: 970 IKLL---LDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFT 1026
+ LL L DP++R T ++ W + L N S+ S + VRE T
Sbjct: 251 VNLLHHMLCVDPMKRATIKDVIAHEWFQKDLPNYLFPPI--NESEASIVDIEAVRE--VT 306
Query: 1027 QPYHLSSD 1034
+ YH++ +
Sbjct: 307 ERYHVAEE 314
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 84.0 bits (206), Expect = 2e-15
Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 18/193 (9%)
Query: 798 IQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
I + YCE + I + ++ Q+E+ + Q+L L Y+HS I+HRD+K NIF+
Sbjct: 79 IVIGYCEGGDMAQAIKKSNGVHFQEEKLCKWLVQLLMGLEYLHSNHILHRDVKCSNIFLT 138
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
+ ++I++GDFGLAK L D TS S +GT Y+ E++ Y
Sbjct: 139 KEQDIRLGDFGLAK-------ILTSDDLTS--------SVVGTPSYMCPELLADI-PYGS 182
Query: 917 KVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDH 976
K D++SLG +EM Y + ++ + I+ S K + ++K +L
Sbjct: 183 KSDIWSLGCCIYEMAY-LKPAFKAFDMQALINKINKTIVSPLPAKYSGPFRGLVKSMLRK 241
Query: 977 DPVRRPTASALLR 989
+P RP+AS LLR
Sbjct: 242 NPEVRPSASDLLR 254
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 84.0 bits (206), Expect = 2e-15
Identities = 59/203 (29%), Positives = 101/203 (49%), Gaps = 22/203 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS ++ MEY L++ + L +E R F+Q++ ++S+ H +G+ HRDLKP N
Sbjct: 144 KSKIYFVMEYVGGGELFNTVAKGRL--PEETARRYFQQLISSVSFCHGRGVYHRDLKPEN 201
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D N+K+ DFGL+ + LR+D G + GT Y+A E++T G
Sbjct: 202 LLLDNKGNLKVSDFGLS----AVAEQLRQD--------GLCHTFCGTPAYIAPEVLTRKG 249
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
K D++S G+I F ++ PF V + KK+ + P F + ++
Sbjct: 250 YDAAKADVWSCGVILFVLMAGHIPFYDKNIMV-MYKKIYKGEFRCPRWFSSDLV----RL 304
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
+ LLD +P R T ++++ W
Sbjct: 305 LTRLLDTNPDTRITIPEIMKNRW 327
>7302511 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 1218
Score = 84.0 bits (206), Expect = 2e-15
Identities = 66/228 (28%), Positives = 111/228 (47%), Gaps = 22/228 (9%)
Query: 792 RKSTLFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKP 850
R+ L+I ME+C +L D+ T L + Y + R+ L+ L Y+HS G +HRD+K
Sbjct: 92 RRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAY--MCRETLKGLEYLHSMGKMHRDIKG 149
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI--I 908
NI + E ++K+ DFG+ + QI+ +R SF IGT ++A E+ +
Sbjct: 150 ANILLTEYGDVKLADFGV--SAQITATINKRKSF------------IGTPYWMAPEVAAV 195
Query: 909 TSHGNYNEKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKLRNIDVEFPS-DFDDKKLHT 965
G YN+ D+++ GI E+ + P + + + + + P+ + DK T
Sbjct: 196 ERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPT 255
Query: 966 EKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPS 1013
IK L +P +RPTA LL+ +V + + KE L+ P+
Sbjct: 256 FHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPN 303
>7291043 [T] KOG0660 Mitogen-activated protein kinase
Length = 392
Score = 84.0 bits (206), Expect = 2e-15
Identities = 47/120 (39%), Positives = 65/120 (54%), Gaps = 8/120 (6%)
Query: 830 QILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGS 889
Q++ A+ +IHS +IHRDLKP NI ID +K+ DFGLA+ + R +
Sbjct: 132 QLINAIKFIHSGNVIHRDLKPSNILIDSKCRLKVADFGLARTLS------SRRIYDDLEQ 185
Query: 890 SGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKL 947
G LT + T Y A EI+ + NY + +DM+ LG I EMI P G VN I+K+
Sbjct: 186 DGMLTDYVATRWYRAPEILVASRNYTKGIDMWGLGCILGEMIRQKPLFQGTSTVNQIEKI 245
>HsM4759010 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 819
Score = 83.6 bits (205), Expect = 2e-15
Identities = 65/228 (28%), Positives = 112/228 (48%), Gaps = 24/228 (10%)
Query: 792 RKSTLFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKP 850
R L+I ME+C +L ++ H T L ++ Y + R+ L+ L ++HSQG IHRD+K
Sbjct: 81 RNDRLWICMEFCGGGSLQEIYHATGPLEERQIAY--VCRERLKGLHHLHSQGKIHRDIKG 138
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI--I 908
N+ + ++K+ DFG++ +++ +R SF IGT ++A E+ +
Sbjct: 139 ANLLLTLQGDVKLADFGVSG--ELTASVAKRRSF------------IGTPYWMAPEVAAV 184
Query: 909 TSHGNYNEKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
G YNE D+++LGI E+ + P + + + + + P DK T+
Sbjct: 185 ERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQ-PPKLRDKTRWTQ 243
Query: 967 K--KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDP 1012
+KL L +P +RPTA LL+ + + L+ + L SDP
Sbjct: 244 NFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDP 291
>Hs7019543 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 547
Score = 83.6 bits (205), Expect = 2e-15
Identities = 66/238 (27%), Positives = 113/238 (46%), Gaps = 31/238 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLI-----HTESLNNQKEE--YWRLFRQILEALSYIHSQGIIH 845
K L++ M+ ++ D+I E N EE + +++LE L Y+H G IH
Sbjct: 133 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIH 192
Query: 846 RDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLR---RDSFTSAGSSGDLTSAIGTALY 902
RDLK NI + E +++I DFG++ + D R R +F +GT +
Sbjct: 193 RDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTF------------VGTPCW 240
Query: 903 VASEIITSHGNYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFD 959
+A E++ Y+ K DM+S GI E+ P+ ++ L+N + +
Sbjct: 241 MAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVE 300
Query: 960 DKKLHTE-----KKIIKLLLDHDPVRRPTASALLRSGWV-PVKNQDELIKEALKNISD 1011
DK++ + +K++ L L DP +RPTA+ LL+ + KN++ LI++ L D
Sbjct: 301 DKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPD 358
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 83.6 bits (205), Expect = 2e-15
Identities = 60/202 (29%), Positives = 99/202 (48%), Gaps = 23/202 (11%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI- 855
++ M+ L+D I + +K+ + +Q+L A+ Y+H GI+HRDLKP N+
Sbjct: 94 YLVMQLVSGGELFDRILERGVYTEKDASL-VIQQVLSAVKYLHENGIVHRDLKPENLLYL 152
Query: 856 --DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+E+ I I DFGL+K Q +G +++A GT YVA E++ +
Sbjct: 153 TPEENSKIMITDFGLSKMEQ----------------NGIMSTACGTPGYVAPEVL-AQKP 195
Query: 914 YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
Y++ VD +S+G+I + ++ YP + +K++ EF S F D + K I
Sbjct: 196 YSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFIC 255
Query: 972 LLLDHDPVRRPTASALLRSGWV 993
LL+ DP R T L W+
Sbjct: 256 HLLEKDPNERYTCEKALSHPWI 277
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 83.6 bits (205), Expect = 2e-15
Identities = 63/203 (31%), Positives = 96/203 (47%), Gaps = 25/203 (12%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S + I MEY LYD I +E + E FRQI+ A+ Y H ++HRDLK NI
Sbjct: 123 SKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENI 181
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+D + NIKI DFGL+ + + F L + G+ LY + EI+
Sbjct: 182 LLDANGNIKIADFGLS-------NLYHQGKF--------LQTFCGSPLYASPEIVNGKPY 226
Query: 914 YNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
+VD +SLG++ + +++ PFD G + ++K++ N P D +I
Sbjct: 227 TGPEVDSWSLGVLLYILVHGTMPFD-GHDHKILVKQISNGAYREPPKPSD-----ACGLI 280
Query: 971 KLLLDHDPVRRPTASALLRSGWV 993
+ LL +P RR T + WV
Sbjct: 281 RWLLMVNPTRRATLEDVASHWWV 303
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 83.6 bits (205), Expect = 2e-15
Identities = 59/203 (29%), Positives = 97/203 (47%), Gaps = 26/203 (12%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +F+ ME L+ I + +E R F+QI+ +SY H+ I+HRDLKP N+
Sbjct: 95 SDIFLVMELVSGGELFSYITRKGALPIRESR-RYFQQIISGVSYCHNHMIVHRDLKPENL 153
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTS-AIGTALYVASEIITSHG 912
+D ++NIKI DFGL+ + + GDL S A G+ Y A E+I++
Sbjct: 154 LLDANKNIKIADFGLSNYM----------------TDGDLLSTACGSPNYAAPELISNKL 197
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD++S G+I + M+ PFD + K+++ P + + +
Sbjct: 198 YVGPEVDLWSCGVILYAMLCGTLPFD-DQNVPTLFAKIKSGRYTVPYSMEKQ----AADL 252
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
I +L DPV+R ++ W
Sbjct: 253 ISTMLQVDPVKRADVKRIVNHSW 275
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 83.6 bits (205), Expect = 2e-15
Identities = 68/215 (31%), Positives = 111/215 (51%), Gaps = 35/215 (16%)
Query: 792 RKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRL-FRQILEALSYIHSQGIIHRDLKP 850
+ ++++ +E+ L + I + L + E+ +L F Q+ A+ Y+H +GI HRDLKP
Sbjct: 232 KPDSVYMVLEFMRGGDLLNRIISNKLLS--EDISKLYFYQMCHAVKYLHDRGITHRDLKP 289
Query: 851 MNIFI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
N+ + DE +K+ DFGL+K VQ +D++ R + GT LYVA E+
Sbjct: 290 DNVLLETNDEETLLKVSDFGLSKFVQ--KDSVMR-------------TLCGTPLYVAPEV 334
Query: 908 ITSHGN--YNEKVDMYSLGIIFFEMI---YPF--DTGMERVNVIKKLRNIDVEFPSDFDD 960
+ + G Y +KVD++SLG++ F + PF + G IKK R F
Sbjct: 335 LITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGR-----FAYGHPS 389
Query: 961 KKLHTE--KKIIKLLLDHDPVRRPTASALLRSGWV 993
K ++ K +I +L DP RRP+ +L+S W+
Sbjct: 390 WKSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWL 424
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 83.6 bits (205), Expect = 2e-15
Identities = 62/200 (31%), Positives = 103/200 (51%), Gaps = 27/200 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQ--KEEYWRLFRQILEALSYIHSQGIIHRDLKP 850
K+ LF+ E+ L DL S N +E R+ ++ AL Y+HS I+HRDLKP
Sbjct: 73 KTDLFVVTEFA----LMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKP 128
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
N+ +D++ + K+ DFGLA+N+ + LTS GT LY+A E++
Sbjct: 129 QNVLLDKNMHAKLCDFGLARNMTLGTHV--------------LTSIKGTPLYMAPELLAE 174
Query: 911 HGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
Y+ DM+SLG I +E + P ++++K +++ DV++PS + +
Sbjct: 175 Q-PYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSEC----RS 229
Query: 969 IIKLLLDHDPVRRPTASALL 988
++ LL+ DP R + + LL
Sbjct: 230 FLQGLLEKDPGLRISWTQLL 249
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 83.2 bits (204), Expect = 3e-15
Identities = 58/209 (27%), Positives = 102/209 (48%), Gaps = 29/209 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ +E C R+L + + E + L RQI+ Y+H +IHRDLK N+F+
Sbjct: 126 VFVVLELCRRRSLLEPHKRRKALTEPEARYYL-RQIVLGCQYLHRNRVIHRDLKLGNLFL 184
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+E +KIGDFGLA V+ + + + GT Y+A E++ S ++
Sbjct: 185 NEDLEVKIGDFGLATKVEYDGERKK--------------TLCGTPNYIAPEVL-SKKEHS 229
Query: 916 EKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+VD++S+G I + ++ PF+T + ++ +N + P + +I+
Sbjct: 230 FEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKN-EYSIPKHINP----VAASLIQK 284
Query: 973 LLDHDPVRRPTASALLR-----SGWVPVK 996
+L DP RPT + LL SG++P +
Sbjct: 285 MLQTDPTARPTINELLNDEFFTSGYIPAR 313
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 83.2 bits (204), Expect = 3e-15
Identities = 70/246 (28%), Positives = 116/246 (46%), Gaps = 38/246 (15%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
F+ MEY L+D I + E RLF+QIL A+ Y H ++HRDLKP N+ +D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEAR-RLFQQILSAVDYCHRHMVVHRDLKPENVLLD 148
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
N KI DFGL+ N+ + LR TS GS Y A E+I+
Sbjct: 149 AHMNAKIADFGLS-NMMSDGEFLR----TSCGSPN----------YTAPEVISGRLYAGP 193
Query: 917 KVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+VD++S G+I + ++ PFD E V + KK+R V + ++ ++ + T ++
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDD--EHVPTLFKKIRG-GVFYIPEYLNRSVAT---LLMH 247
Query: 973 LLDHDPVRRPTASALLRSGWV------------PVKNQDELIKEALKNISDPSSPWQQQV 1020
+L DP++R T + W P + + + EA+K + + + +V
Sbjct: 248 MLQVDPLKRATIKDIREHEWFKQGLPSYLFPEDPSYDANVIDDEAVKEVCEKFECTESEV 307
Query: 1021 RENLFT 1026
+L++
Sbjct: 308 MNSLYS 313
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 83.2 bits (204), Expect = 3e-15
Identities = 68/247 (27%), Positives = 119/247 (47%), Gaps = 45/247 (18%)
Query: 796 LFIQMEYCENRTLYDLIHTES-LNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
++ +E C +L +L L + ++ + Q+ E + ++H+ IIHRDLK N+F
Sbjct: 108 VYFTLELCSKNSLMELNKQRGPLTEHEARFYTI--QVAEGVKHLHNLQIIHRDLKLGNLF 165
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
++E +KIGDFGLA + ++ + R GT Y+A E++ G+
Sbjct: 166 LNEHLQVKIGDFGLATFCEKNEKKMTRG---------------GTPNYIAPEVLNETGHA 210
Query: 915 NEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
E VD++++G I + +++ PF++ + + +++N D P + T ++I+
Sbjct: 211 FE-VDIWAIGCILYVLLFGSPPFESRRVQETYV-RIKNNDYVVPENASP----TANRLIR 264
Query: 972 LLLDHDPVRRPTASALL---------RSGWVPV-----KNQD----ELIKEALKNISDPS 1013
LLD P RRPTA A+L + PV K QD I L ++ +P
Sbjct: 265 SLLDPVPDRRPTAEAVLLDQFFKTTIEPTYPPVHQQLHKEQDVKYFAPINPVLPHVEEPI 324
Query: 1014 SPWQQQV 1020
SP Q+V
Sbjct: 325 SPIYQEV 331
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 83.2 bits (204), Expect = 3e-15
Identities = 65/201 (32%), Positives = 100/201 (49%), Gaps = 27/201 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+++ MEY ++ L+D I E Q++E LF+QI+ + Y H I+HRDLKP N+ +
Sbjct: 92 IYVVMEYVKSGELFDYI-VEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLL 150
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D NIKI DFGL+ NV L+ TS GS Y A E+I S Y
Sbjct: 151 DSQCNIKIVDFGLS-NVMHDGHFLK----TSCGSPN----------YAAPEVI-SGKPYG 194
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
VD++S G+I + ++ PFD E + NV +K++ P+ H + +I
Sbjct: 195 PDVDIWSCGVILYALLCGTLPFDD--ENIPNVFEKIKRGMYTLPNHLS----HFARDLIP 248
Query: 972 LLLDHDPVRRPTASALLRSGW 992
+L DP R + + + + W
Sbjct: 249 RMLMVDPTMRISITEIRQHPW 269
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 594
Score = 83.2 bits (204), Expect = 3e-15
Identities = 64/214 (29%), Positives = 103/214 (47%), Gaps = 26/214 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ ME CE L D I + + R+ QIL A ++ H QG++HRDLKP N F+
Sbjct: 220 VFVVMELCEGGELLDRILARGGRYPEVDAKRILVQILSATAFFHLQGVVHRDLKPEN-FL 278
Query: 856 DESRN----IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
SRN +K+ DFGL+ ++ Q L +G+A YVA E++ H
Sbjct: 279 FTSRNEDAILKVIDFGLSDFIRYDQ---------------RLNDVVGSAYYVAPEVL--H 321
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
+Y+ + DM+S+G+I + ++ PF G + + + + F T K
Sbjct: 322 RSYSTEADMWSIGVISYILLCGSRPF-YGRTESAIFRCVLRANPNFEDMPWPSISPTAKD 380
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELI 1002
+K LL+ D +R TA+ L W+ +N L+
Sbjct: 381 FVKRLLNKDHRKRMTAAQALAHPWLRDENPGLLL 414
>At1g53570 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 608
Score = 83.2 bits (204), Expect = 3e-15
Identities = 59/198 (29%), Positives = 94/198 (46%), Gaps = 20/198 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL + +EY +++ L+ + + RQIL L+Y+H + +HRD+K N
Sbjct: 286 EETLSVYLEYVSGGSIHKLLKDYG-SFTEPVIQNYTRQILAGLAYLHGRNTVHRDIKGAN 344
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
I +D + IK+ DFG+AK+V + + S G+ ++A E++ S
Sbjct: 345 ILVDPNGEIKLADFGMAKHVT---------------AFSTMLSFKGSPYWMAPEVVMSQN 389
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
Y VD++SLG EM P + E V I K+ N + + D + K I
Sbjct: 390 GYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGN--SKDTPEIPDHLSNDAKNFI 447
Query: 971 KLLLDHDPVRRPTASALL 988
+L L +P RPTAS LL
Sbjct: 448 RLCLQRNPTVRPTASQLL 465
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 83.2 bits (204), Expect = 3e-15
Identities = 64/208 (30%), Positives = 101/208 (47%), Gaps = 30/208 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
S L++ +EY ++ H + E + R + QI+ A Y+H +I+RDLKP N
Sbjct: 117 SNLYMVLEYVPGGEMFS--HLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPEN 174
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ ID +K+ DFG AK V+ G + GT Y+A EII S G
Sbjct: 175 LLIDSQGYLKVTDFGFAKRVK-----------------GRTWTLCGTPEYLAPEIILSKG 217
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YN+ VD ++LG++ +EM YP + + + +K+ + V FPS F K ++
Sbjct: 218 -YNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDL----KDLL 272
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQ 998
+ LL D +R L++G +KNQ
Sbjct: 273 RNLLQVDLTKR---YGNLKAGVNDIKNQ 297
>Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 681
Score = 82.8 bits (203), Expect = 4e-15
Identities = 64/202 (31%), Positives = 99/202 (48%), Gaps = 34/202 (16%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ ME+ + L D++ LN +E+ + +L+AL+Y+H+QG+IHRD+K +I +
Sbjct: 477 LWVLMEFLQGGALTDIVSQVRLN--EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILL 534
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+K+ DFG QIS+D +R S +GT ++A E+I S Y
Sbjct: 535 TLDGRVKLSDFGFC--AQISKDVPKRKSL------------VGTPYWMAPEVI-SRSLYA 579
Query: 916 EKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLL 973
+VD++SLGI+ EM+ P V +K+LR D KL K+ +L
Sbjct: 580 TEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLR--------DSPPPKLKNSHKVSPVL 631
Query: 974 LD-------HDPVRRPTASALL 988
D DP R TA LL
Sbjct: 632 RDFLERMLVRDPQERATAQELL 653
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 82.8 bits (203), Expect = 4e-15
Identities = 60/191 (31%), Positives = 93/191 (48%), Gaps = 27/191 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
S L++ MEY ++ H + E + R + QI+ Y+HS +I+RDLKP N
Sbjct: 115 SNLYMVMEYVPGGEMFS--HLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPEN 172
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ ID I++ DFG AK V+ G + GT Y+A EII S G
Sbjct: 173 LLIDHQGYIQVTDFGFAKRVK-----------------GRTWTLCGTPEYLAPEIILSKG 215
Query: 913 NYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
YN+ VD ++LG++ +EM YP + + + +K+ + V FPS F K ++
Sbjct: 216 -YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL----KDLL 270
Query: 971 KLLLDHDPVRR 981
+ LL D +R
Sbjct: 271 RNLLQVDLTKR 281
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 82.8 bits (203), Expect = 4e-15
Identities = 60/201 (29%), Positives = 101/201 (49%), Gaps = 26/201 (12%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
F+ EY + R LYD+I + +KE R FRQ+L A+ YIH ++HRDLK NI ID
Sbjct: 138 FLIFEYVKGRQLYDIIISSGPLKEKEGQ-RYFRQLLSAIDYIHRNSVVHRDLKIENILID 196
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
E+ N+K+ DFGL+ TL L + G+ + A E++
Sbjct: 197 ENDNVKLIDFGLSN--FYDNKTL-------------LNTFCGSLYFAAPELLQGQRYCGP 241
Query: 917 KVDMYSLGIIFFEMI---YPFDTGMERVNVIK-KLRNIDVEFPSDFDDKKLHTEKKIIKL 972
++D++SLG++ + ++ PFD E V ++ K+ + D +F + + ++I+
Sbjct: 242 EIDVWSLGVVLYAILCGCVPFDD--EDVQGLQAKIMDADFKFCKTISREAM----ELIRG 295
Query: 973 LLDHDPVRRPTASALLRSGWV 993
++ P R S ++ S WV
Sbjct: 296 MIVAQPSSRMGLSQVIGSEWV 316
>CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1096
Score = 82.8 bits (203), Expect = 4e-15
Identities = 63/236 (26%), Positives = 117/236 (48%), Gaps = 22/236 (9%)
Query: 783 MKSLSVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQ 841
+K L + + L++ ME+C + ++ DL+ + KEE+ + R+IL L ++H
Sbjct: 86 IKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQS 145
Query: 842 GIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTAL 901
+IHRD+K N+ + +S +K+ DFG+ + Q+ + RR++F IGT
Sbjct: 146 KVIHRDIKGQNVLLTDSAEVKLVDFGV--SAQLDKTVGRRNTF------------IGTPY 191
Query: 902 YVASEII----TSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSD 957
++A E+I + Y+ + D++SLGI EM + ++ ++ L I P
Sbjct: 192 WMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCD-MHPMRALFLIPRNPPPK 250
Query: 958 FDDKKLHTEK--KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
K T+K I+ +L D +RP ALLR ++ + ++ I+ ++K D
Sbjct: 251 LKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQTIRHSIKEHID 306
>CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1082
Score = 82.8 bits (203), Expect = 4e-15
Identities = 63/236 (26%), Positives = 117/236 (48%), Gaps = 22/236 (9%)
Query: 783 MKSLSVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQ 841
+K L + + L++ ME+C + ++ DL+ + KEE+ + R+IL L ++H
Sbjct: 86 IKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQS 145
Query: 842 GIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTAL 901
+IHRD+K N+ + +S +K+ DFG+ + Q+ + RR++F IGT
Sbjct: 146 KVIHRDIKGQNVLLTDSAEVKLVDFGV--SAQLDKTVGRRNTF------------IGTPY 191
Query: 902 YVASEII----TSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSD 957
++A E+I + Y+ + D++SLGI EM + ++ ++ L I P
Sbjct: 192 WMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCD-MHPMRALFLIPRNPPPK 250
Query: 958 FDDKKLHTEK--KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
K T+K I+ +L D +RP ALLR ++ + ++ I+ ++K D
Sbjct: 251 LKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQTIRHSIKEHID 306
>CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and related germinal
center kinase (GCK) family protein kinases
Length = 1087
Score = 82.8 bits (203), Expect = 4e-15
Identities = 63/236 (26%), Positives = 117/236 (48%), Gaps = 22/236 (9%)
Query: 783 MKSLSVKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQ 841
+K L + + L++ ME+C + ++ DL+ + KEE+ + R+IL L ++H
Sbjct: 86 IKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKGGSLKEEWIAYICREILRGLYHLHQS 145
Query: 842 GIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTAL 901
+IHRD+K N+ + +S +K+ DFG+ + Q+ + RR++F IGT
Sbjct: 146 KVIHRDIKGQNVLLTDSAEVKLVDFGV--SAQLDKTVGRRNTF------------IGTPY 191
Query: 902 YVASEII----TSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSD 957
++A E+I + Y+ + D++SLGI EM + ++ ++ L I P
Sbjct: 192 WMAPEVIACDESPEATYDSRSDLWSLGITALEMAEGHPPLCD-MHPMRALFLIPRNPPPK 250
Query: 958 FDDKKLHTEK--KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
K T+K I+ +L D +RP ALLR ++ + ++ I+ ++K D
Sbjct: 251 LKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFIKEQPHEQTIRHSIKEHID 306
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 82.8 bits (203), Expect = 4e-15
Identities = 55/204 (26%), Positives = 102/204 (49%), Gaps = 28/204 (13%)
Query: 797 FIQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
FI MEYC ++D ++ E L + ++ FRQ++ A++++HSQG HRDLKP N+ +
Sbjct: 83 FIVMEYCSGGEMFDYIVRKERLEESEARHF--FRQLVSAIAFVHSQGYAHRDLKPENLLL 140
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
E ++K+ DFGL + + +L + G+ Y A E+I
Sbjct: 141 TEDLHLKLIDFGLCAKTEKGRI-----------DKHNLDTCCGSPAYAAPELIQGLQYKG 189
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRN---IDVEFPSDFDDKKLHTEKKI 969
+ D++S+GI+ + ++ PF+ ++ + KK+++ + EF S K++
Sbjct: 190 NEADVWSMGILLYTLLVGALPFEDDNMQI-MYKKIQSGCFYEPEFLSPL-------SKQL 241
Query: 970 IKLLLDHDPVRRPTASALLRSGWV 993
++ +L P RR + LL W+
Sbjct: 242 LRAMLQVVPERRISVKKLLEHDWL 265
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 82.8 bits (203), Expect = 4e-15
Identities = 57/216 (26%), Positives = 108/216 (49%), Gaps = 30/216 (13%)
Query: 794 STLFIQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
S ++I +E+ L+D ++H L ++ E + F+Q+++A+++ H +G+ HRDLKP N
Sbjct: 82 SKIYIVLEFVTGGELFDRIVHKGRL--EESESRKYFQQLVDAVAHCHCKGVYHRDLKPEN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D + N+K+ DFGL+ Q + LR + GT YVA E+++ G
Sbjct: 140 LLLDTNGNLKVSDFGLSALPQEGVELLR--------------TTCGTPNYVAPEVLSGQG 185
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
D++S G+I F ++ PF + + + +K+ + P F + K +
Sbjct: 186 YDGSAADIWSCGVILFVILAGYLPF-SETDLPGLYRKINAAEFSCPPWFSAE----VKFL 240
Query: 970 IKLLLDHDPVRRPTASALLRSGW-----VPVKNQDE 1000
I +LD +P R + + W VP++ ++E
Sbjct: 241 IHRILDPNPKTRIQIQGIKKDPWFRLNYVPIRAREE 276
>SPBC660.14 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 581
Score = 82.4 bits (202), Expect = 6e-15
Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 19/136 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEY--WRLFRQILEALSYIHSQGIIHRDLKPMNI 853
+F+Q++YCEN L + L + + W++ Q+ +AL++IH +H D+KP N+
Sbjct: 364 IFLQLDYCENGDLSLFLSELGLLQVMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNV 423
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
I N+K+GDFGLA ++ +S + G +Y+A EI+ SH N
Sbjct: 424 LITRDGNLKLGDFGLATSLPVS----------------SMVDLEGDRVYIAPEILASH-N 466
Query: 914 YNEKVDMYSLGIIFFE 929
Y + D+YSLG+ E
Sbjct: 467 YGKPADVYSLGLSMIE 482
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 82.4 bits (202), Expect = 6e-15
Identities = 58/201 (28%), Positives = 99/201 (48%), Gaps = 26/201 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+++ MEY + L+D I E Q++E F+QI+ + Y H ++HRDLKP N+ +
Sbjct: 92 IYLVMEYVNSGELFDYI-VEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLL 150
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D N+KI DFGL+ + +R F L ++ G+ Y A E+I+
Sbjct: 151 DSKCNVKIADFGLS-------NIMRDGHF--------LKTSCGSPNYAAPEVISGKLYAG 195
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
+VD++S G+I + ++ PFD E + N+ KK++ PS + +I
Sbjct: 196 PEVDVWSCGVILYALLCGTLPFDD--ENIPNLFKKIKGGIYTLPSHLSP----GARDLIP 249
Query: 972 LLLDHDPVRRPTASALLRSGW 992
+L DP++R T + + W
Sbjct: 250 RMLVVDPMKRVTIPEIRQHPW 270
>7300224 [T] KOG0201 Serine/threonine protein kinase
Length = 642
Score = 82.4 bits (202), Expect = 6e-15
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 32/244 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L+I MEY + DL+ S ++ + R++L+ L Y+HS+ +HRD+K N+ +
Sbjct: 84 LWIIMEYLGGGSALDLMKAGSF--EEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLL 141
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
E ++K+ DFG+A Q++ T +R++F +GT ++A E+I Y+
Sbjct: 142 SEQGDVKLADFGVAG--QLTNTTSKRNTF------------VGTPFWMAPEVI-KQSQYD 186
Query: 916 EKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLD 975
K D++SLGI E+ E ++ ++ L I P + K ++ L+
Sbjct: 187 AKADIWSLGITAIELAKGEPPNSE-LHPMRVLFLIPKNNPPQLTGSYTKSFKDFVEACLN 245
Query: 976 HDPVRRPTASALLRSGWVPVKNQDELIKEALKN-----ISDPSSPWQQQVRENLFTQPYH 1030
DP RPTA LL+ IK+A KN + D W+ + T+ +
Sbjct: 246 KDPENRPTAKELLKY---------PFIKKAKKNAYLIDLIDRFKKWKVSKGDESETESEN 296
Query: 1031 LSSD 1034
SD
Sbjct: 297 SDSD 300
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 82.0 bits (201), Expect = 7e-15
Identities = 76/266 (28%), Positives = 129/266 (47%), Gaps = 39/266 (14%)
Query: 796 LFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+F+ M+Y E L+ L+ ++ N +++ ++ AL Y+HS+ II+RDLKP NI
Sbjct: 161 VFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA--EVCLALEYLHSKDIIYRDLKPENIL 218
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+D++ +IKI DFG AK V TL GT Y+A E++++ Y
Sbjct: 219 LDKNGHIKITDFGFAKYVPDVTYTL-----------------CGTPDYIAPEVVSTK-PY 260
Query: 915 NEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI---DVEFPSDFDDKKLHTEKKIIK 971
N+ VD +S G++ +EM+ + T N +K NI +++FP F + ++K
Sbjct: 261 NKSVDWWSFGVLIYEMLAGY-TPFYNSNTMKTYENILNAELKFPPFFHP----DAQDLLK 315
Query: 972 LLLDHDPVRRPTASALLRSGWVPVKNQ---DELIKEAL--KNISDPSSPWQQQVRENLFT 1026
L+ D R L++G VKN +E+I E L + I P P QQ + + T
Sbjct: 316 KLITRDLSER---LGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGD--T 370
Query: 1027 QPYHLSSDILFDLSRSDTTPFLQLLR 1052
+ + F+ P++ L++
Sbjct: 371 SQFDRYPEEEFNYGIQGEDPYMDLMK 396
>SPAC31G5.09c [T] KOG0660 Mitogen-activated protein kinase
Length = 372
Score = 82.0 bits (201), Expect = 7e-15
Identities = 58/181 (32%), Positives = 92/181 (50%), Gaps = 17/181 (9%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
++I E E LY +I ++ L++ +Y+ QIL AL +HS G++HRDLKP N+ +
Sbjct: 115 VYIVQELMET-DLYRVIRSQPLSDDHCQYFTY--QILRALKAMHSAGVVHRDLKPSNLLL 171
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+ + ++K+ DFGLA R + G+ G +T + T Y A EI+ S Y+
Sbjct: 172 NANCDLKVADFGLA-----------RSTTAQGGNPGFMTEYVATRWYRAPEIMLSFREYS 220
Query: 916 EKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNI-DVEFPSDFDDKKLHTEKKIIKL 972
+ +D++S G I EM+ P G + + I + NI DF K +K IK
Sbjct: 221 KAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKSARARKYIKS 280
Query: 973 L 973
L
Sbjct: 281 L 281
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 82.0 bits (201), Expect = 7e-15
Identities = 59/207 (28%), Positives = 105/207 (50%), Gaps = 25/207 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI-F 854
+++ E + L D I + +++E LF I + + Y+H+QG++HRDLKP NI +
Sbjct: 489 VYVVTELMKGGELLDKILRQKFFSEREASAVLFT-ITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 855 IDESRN---IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+DES N I+I DFG AK ++ +G L + TA +VA E++
Sbjct: 548 VDESGNPESIRICDFGFAKQLR--------------AENGLLMTPCYTANFVAPEVLKRQ 593
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERV--NVIKKLRNIDVEFPSDFDDKKLHTE 966
G Y+ D++SLG++ + M+ PF G + ++ ++ + + + T
Sbjct: 594 G-YDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTA 652
Query: 967 KKIIKLLLDHDPVRRPTASALLRSGWV 993
K ++ +L DP +R TA+ +LR W+
Sbjct: 653 KDLVSKMLHVDPHQRLTAALVLRHPWI 679
Score = 70.5 bits (171), Expect = 2e-11
Identities = 50/189 (26%), Positives = 89/189 (46%), Gaps = 24/189 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ +++ L+ + E + +++ + L L AL ++HS GII+RDLKP NI +
Sbjct: 143 LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELAL-ALDHLHSLGIIYRDLKPENILL 201
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
DE +IK+ DFGL+K S S GT Y+A E++ G +
Sbjct: 202 DEEGHIKLTDFGLSKE--------------SIDHEKKAYSFCGTVEYMAPEVVNRRG-HT 246
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+ D +S G++ FEM+ PF G +R + + + P + + ++++
Sbjct: 247 QSADWWSFGVLMFEMLTGTLPFQ-GKDRKETMTMILKAKLGMPQFLSPE----AQSLLRM 301
Query: 973 LLDHDPVRR 981
L +P R
Sbjct: 302 LFKRNPANR 310
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 534
Score = 82.0 bits (201), Expect = 7e-15
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 24/220 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L + ME C L+D I + ++KE +FRQI+ + H G++HRDLKP N
Sbjct: 156 KDNLHLVMELCSGGELFDRIIKKGSYSEKEAA-NIFRQIVNVVHVCHFMGVVHRDLKPEN 214
Query: 853 IFI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
+ +E IK DFGL +V I + + RD +G+A YVA E++
Sbjct: 215 FLLVSNEEDSPIKATDFGL--SVFIEEGKVYRD-------------IVGSAYYVAPEVL- 258
Query: 910 SHGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
H NY +++D++S G++ + ++ P G + + + ++ + + K
Sbjct: 259 -HRNYGKEIDVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAK 317
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV-PVKNQDELIKEAL 1006
+I+ +L DP +R TA+ L W+ K D+ I A+
Sbjct: 318 DLIRKMLIRDPKKRITAAEALEHPWMTDTKISDKPINSAV 357
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 82.0 bits (201), Expect = 7e-15
Identities = 50/198 (25%), Positives = 97/198 (48%), Gaps = 24/198 (12%)
Query: 800 MEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDES 858
ME C L D ++ + Q+ +F+ ++ ++Y H G++HRD+KP NI + +
Sbjct: 178 MELCSGGRLIDQMVKVGRYSEQRAA--NIFKDLMLVINYCHEMGVVHRDIKPENILLTAA 235
Query: 859 RNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKV 918
I++ DFGLA + Q L+ G+ YVA E+++ NY+EKV
Sbjct: 236 GKIQLADFGLAMRIAKGQ---------------TLSGLAGSPAYVAPEVLSE--NYSEKV 278
Query: 919 DMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLD 975
D++S G++ + + + PF G + + ++N+ ++F + + + ++ +L
Sbjct: 279 DVWSAGVLLYALLSGVLPF-KGDSLDAIFEAIKNVKLDFNTGVWESVSKPARDLLARMLT 337
Query: 976 HDPVRRPTASALLRSGWV 993
+ R TA +LR W+
Sbjct: 338 REESARITADEVLRHPWI 355
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 82.0 bits (201), Expect = 7e-15
Identities = 66/266 (24%), Positives = 121/266 (44%), Gaps = 36/266 (13%)
Query: 745 GVSKASASEVTG-----LDSSKNDTLQEDGIGDMKFGRDKRSKMK------SLSVKSPRK 793
GV + + ++TG SK+ + +D + +K +K+ +L K
Sbjct: 56 GVIRVCSDKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLAGHPNVVNLKAVYEEK 115
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKPMN 852
++ + ME C L+ + E E R LF+ +++ + + H GI+HRDLKP N
Sbjct: 116 DSVHLVMELCAGGELFHKL--EKYGRYSEVRARVLFKHLMQVVKFCHDSGIVHRDLKPEN 173
Query: 853 IF---IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
I + S IK+ DFGLA ++ + L+ +G+ Y+A E++
Sbjct: 174 ILMATMSSSSPIKLADFGLATYIKPGE---------------KLSGTVGSPFYIAPEVLA 218
Query: 910 SHGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
G YN+ D++S G+I + ++ P G + + +R D+ F ++ D K
Sbjct: 219 --GGYNQAADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAK 276
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
+I+ +L DP +R +A +L W+
Sbjct: 277 DLIRGMLCVDPSQRLSADEVLAHSWM 302
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 81.6 bits (200), Expect = 9e-15
Identities = 72/264 (27%), Positives = 116/264 (43%), Gaps = 44/264 (16%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +F+ MEY L+D I ++KE RLF+QIL + Y H ++HRDLKP N+
Sbjct: 89 SDIFMVMEYVSGGELFDYICKNGRLDEKESR-RLFQQILSGVDYCHRHMVVHRDLKPENV 147
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+D N KI DFGL+ N+ + LR TS GS Y A E+I+
Sbjct: 148 LLDAHMNAKIADFGLS-NMMSDGEFLR----TSCGSPN----------YAAPEVISGRLY 192
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
+VD++S G+I + ++ PFD + KK+ + P + + ++
Sbjct: 193 AGPEVDIWSSGVILYALLCGTLPFDDD-HVPTLFKKICDGIFYTPQYLNPSVI----SLL 247
Query: 971 KLLLDHDPVRRPTASALLRSGWV------------PVKNQDELIKEALKNISDPSSPWQQ 1018
K +L DP++R + + W P + + EALK + + ++
Sbjct: 248 KHMLQVDPMKRASIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEE 307
Query: 1019 QVRENLFTQ--------PYHLSSD 1034
+V L+ + YHL D
Sbjct: 308 EVLSCLYNRNHQDPLAVAYHLIID 331
>Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 476
Score = 81.6 bits (200), Expect = 9e-15
Identities = 67/251 (26%), Positives = 112/251 (43%), Gaps = 38/251 (15%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
++ +EYC L+D I + + + + R F Q++ + Y+H GI HRD+KP N+ +D
Sbjct: 81 YLFLEYCSGGELFDRIEPD-IGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLD 139
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
E N+KI DFGLA F L GT YVA E++ + E
Sbjct: 140 ERDNLKISDFGLA------------TVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAE 187
Query: 917 KVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKK--LHTEKKI-- 969
VD++S GI+ M+ P+D + + SD+ +KK L+ KKI
Sbjct: 188 PVDVWSCGIVLTAMLAGELPWDQPSD-----------SCQEYSDWKEKKTYLNPWKKIDS 236
Query: 970 -----IKLLLDHDPVRRPTASALLRSGWV--PVKNQDELIKEALKNISDPSSPWQQQVRE 1022
+ +L +P R T + + W P+K + + +S+ S + + ++
Sbjct: 237 APLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTSGGVSESPSGFSKHIQS 296
Query: 1023 NLFTQPYHLSS 1033
NL P + +S
Sbjct: 297 NLDFSPVNSAS 307
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 81.3 bits (199), Expect = 1e-14
Identities = 49/137 (35%), Positives = 77/137 (55%), Gaps = 21/137 (15%)
Query: 796 LFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+F+ M+Y E L+ L+ ++ N +++ +++ AL Y+H+ II+RDLKP NI
Sbjct: 143 IFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAA--EVILALEYLHAHNIIYRDLKPENIL 200
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+D + +IKI DFG AK VQ TL GT Y+A E+IT+ Y
Sbjct: 201 LDRNGHIKITDFGFAKEVQTVTWTL-----------------CGTPDYIAPEVITTK-PY 242
Query: 915 NEKVDMYSLGIIFFEMI 931
N+ VD +SLG++ +EM+
Sbjct: 243 NKSVDWWSLGVLIYEML 259
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 81.3 bits (199), Expect = 1e-14
Identities = 56/202 (27%), Positives = 99/202 (48%), Gaps = 28/202 (13%)
Query: 796 LFIQMEYCENRTLY-DLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+++ +EY T+Y +L + Q+ L+ +I ALSY HS+ +IHRD+KP N+
Sbjct: 205 VYLILEYAPLGTVYRELQKLSKFDEQRTA--NLYNRIANALSYCHSKRVIHRDIKPENLL 262
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+ + +KI DFG + + S+ T+ GT Y+ E+I +
Sbjct: 263 LGSAGELKIADFGWSVHAPSSR----------------RTTLCGTLDYLPPEMIEGR-MH 305
Query: 915 NEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
+EKVD++SLG++ +E + PF+ + K++ ++ FP D + +I
Sbjct: 306 DEKVDLWSLGVLCYEFLVGKPPFEANTYQ-ETYKRISRVEFTFP----DFVTEGARDLIS 360
Query: 972 LLLDHDPVRRPTASALLRSGWV 993
LL H+P +RP +L W+
Sbjct: 361 RLLKHNPSQRPMLREVLEHPWI 382
>Hs6005810 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 833
Score = 81.3 bits (199), Expect = 1e-14
Identities = 73/233 (31%), Positives = 117/233 (49%), Gaps = 41/233 (17%)
Query: 796 LFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
L+I ME+C +L D+ T SL+ + Y + R++L+ L+Y+HSQ IHRD+K NI
Sbjct: 87 LWICMEFCGAGSLQDIYQVTGSLSELQISY--VCREVLQGLAYLHSQKKIHRDIKGANIL 144
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI--ITSHG 912
I+++ +++ DFG+ + QI RR SF IGT ++A E+ + G
Sbjct: 145 INDAGEVRLADFGI--SAQIGATLARRLSF------------IGTPYWMAPEVAAVALKG 190
Query: 913 NYNEKVDMYSLGIIFFEM--IYP--FDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
YNE D++SLGI E+ + P FD + LR + + S + +L + K
Sbjct: 191 GYNELCDIWSLGITAIELAELQPPLFD--------VHPLRVLFLMTKSGYQPPRLKEKGK 242
Query: 969 -------IIKLLLDHDPVRRPTASALLRSGWV--PVKNQDELIKEALKNISDP 1012
IK+ L P +RP+A+ +L V P N+ LI + L + +P
Sbjct: 243 WSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRG-LILDLLDKLKNP 294
>Hs20070158 [T] KOG0201 Serine/threonine protein kinase
Length = 443
Score = 81.3 bits (199), Expect = 1e-14
Identities = 56/202 (27%), Positives = 102/202 (49%), Gaps = 18/202 (8%)
Query: 792 RKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
+ + L+I MEY + DL+ L+ + + + R+IL+ L Y+HS+ IHRD+K
Sbjct: 103 KDTKLWIIMEYLGGGSALDLLEPGPLD--ETQIATILREILKGLDYLHSEKKIHRDIKAA 160
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
N+ + E +K+ DFG+A Q++ ++R++F +GT ++A E+I
Sbjct: 161 NVLLSEHGEVKLADFGVAG--QLTDTQIKRNTF------------VGTPFWMAPEVI-KQ 205
Query: 912 GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
Y+ K D++SLGI E+ + ++ +K L I P + K+ ++
Sbjct: 206 SAYDSKADIWSLGITAIELARG-EPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVE 264
Query: 972 LLLDHDPVRRPTASALLRSGWV 993
L+ +P RPTA LL+ ++
Sbjct: 265 ACLNKEPSFRPTAKELLKHKFI 286
>Hs15011880 [T] KOG0201 Serine/threonine protein kinase
Length = 416
Score = 81.3 bits (199), Expect = 1e-14
Identities = 62/207 (29%), Positives = 107/207 (50%), Gaps = 25/207 (12%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S L+I MEY + DL+ + + + + ++IL+ L Y+HS+ IHRD+K N+
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFD--EFQIATMLKEILKGLDYLHSEKKIHRDIKAANV 150
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+ E ++K+ DFG+A Q++ ++R++F +GT ++A E+I
Sbjct: 151 LLSEQGDVKLADFGVAG--QLTDTQIKRNTF------------VGTPFWMAPEVI-QQSA 195
Query: 914 YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKL-RNIDVEFPSDFDDKKLHTEKKII 970
Y+ K D++SLGI E+ P ++ M + V+ + +N DF + K+ I
Sbjct: 196 YDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDF----TKSFKEFI 251
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKN 997
L+ DP RPTA LL+ ++ VKN
Sbjct: 252 DACLNKDPSFRPTAKELLKHKFI-VKN 277
>Hs14771959 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 719
Score = 81.3 bits (199), Expect = 1e-14
Identities = 61/197 (30%), Positives = 100/197 (49%), Gaps = 24/197 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ ME+ E L D++ +N +E+ + +L ALSY+H+QG+IHRD+K +I +
Sbjct: 519 LWVVMEFLEGGALTDIVTHTRMN--EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILL 576
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
IK+ DFG Q+S++ +R S +GT ++A E+I S Y
Sbjct: 577 TSDGRIKLSDFGFC--AQVSKEVPKRKSL------------VGTPYWMAPEVI-SRLPYG 621
Query: 916 EKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK---- 971
+VD++SLGI+ EMI + ++ +R I P D LH +++
Sbjct: 622 TEVDIWSLGIMVIEMI-DGEPPYFNEPPLQAMRRIRDSLPPRVKD--LHKVSSVLRGFLD 678
Query: 972 LLLDHDPVRRPTASALL 988
L+L +P +R TA LL
Sbjct: 679 LMLVREPSQRATAQELL 695
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 81.3 bits (199), Expect = 1e-14
Identities = 66/233 (28%), Positives = 115/233 (49%), Gaps = 32/233 (13%)
Query: 798 IQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
I + YC+ + + I + +E+ + Q+L AL Y+H+ I+HRD+K NIF+
Sbjct: 79 IVIGYCKGGDMAEAIKKANGVEFSEEKLCKWLVQLLMALEYLHASHILHRDVKCSNIFLT 138
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDL-TSAIGTALYVASEIITSHGNYN 915
+ ++I++GDFGLAK + +S DL +S +GT Y+ E++ Y
Sbjct: 139 KDQDIRLGDFGLAKIL----------------TSDDLASSVVGTPSYMCPELLADI-PYG 181
Query: 916 EKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKL-RNIDVEFPSDFDDKKLHTEKKIIKL 972
K D++SLG +EM + P + +I ++ R+I P+ + + ++K
Sbjct: 182 SKSDIWSLGCCMYEMTALKPAFKAFDMQGLINRINRSIVAPLPAQYST----AFRSLVKS 237
Query: 973 LLDHDPVRRPTASALLRSGWVPVKNQDELIK------EALKNISDPSSPWQQQ 1019
+L +P RP+AS LLR + Q L+K + L + S+ S + QQ
Sbjct: 238 MLRKNPELRPSASDLLRQPLLQPYVQKVLLKLSFREHDTLPSESERRSSYPQQ 290
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 81.3 bits (199), Expect = 1e-14
Identities = 56/207 (27%), Positives = 101/207 (48%), Gaps = 26/207 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ +EY LY ++ + +++ + +AL+Y H + +IHRD+KP N+ +
Sbjct: 95 IFLILEYAHGGELYGVLKQNG-HLTEQQAATYIASLSQALAYCHGKCVIHRDIKPENLLL 153
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D +KI DFG S SS + GT Y+A E++ + +++
Sbjct: 154 DHEGRLKIADFG-----------------WSVQSSNKRKTMCGTLDYLAPEMVENR-DHD 195
Query: 916 EKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
VD ++LGI+ +E +Y PF+ ++ + K++ ID+ FP K +I
Sbjct: 196 YAVDNWTLGILCYEFLYGNPPFEAESQK-DTFKRILKIDLSFP--LTPNVSEEAKNLISQ 252
Query: 973 LLDHDPVRRPTASALLRSGWVPVKNQD 999
LL DP +R + +++ W+ VKN D
Sbjct: 253 LLVKDPSKRLSIEKIMQHPWI-VKNAD 278
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 81.3 bits (199), Expect = 1e-14
Identities = 62/212 (29%), Positives = 97/212 (45%), Gaps = 24/212 (11%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
+ ++I ME CE L D I + + + QIL +++ H QG++HRDLKP N
Sbjct: 225 ANVYIAMELCEGGELLDRILARGGKYSENDAKPVIIQILNVVAFCHFQGVVHRDLKPENF 284
Query: 854 FI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
+E+ +K DFGL+ D +R D L +G+A YVA E++
Sbjct: 285 LYTSKEENSQLKAIDFGLS-------DFVRPDE--------RLNDIVGSAYYVAPEVL-- 327
Query: 911 HGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
H +Y + D++S+G+I + ++ PF E + + + D F K
Sbjct: 328 HRSYTTEADVWSIGVIAYILLCGSRPFWARTES-GIFRAVLKADPSFDEPPWPFLSSDAK 386
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQD 999
+K LL DP RR +AS L W+ N D
Sbjct: 387 DFVKRLLFKDPRRRMSASQALMHPWIRAYNTD 418
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 80.9 bits (198), Expect = 2e-14
Identities = 65/202 (32%), Positives = 97/202 (47%), Gaps = 27/202 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNN-QKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
+S +++ +EYC + LYD H SL E LF QI A+ Y HS +HRDLK
Sbjct: 104 ESKVWMALEYCPGKELYD--HLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLE 161
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
NI +D++ N K+ DFG + + L + GT +Y+A E+I
Sbjct: 162 NILLDKNGNAKLTDFGFTRECM---------------TKTTLETVCGTTVYMAPELIERR 206
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE-K 967
K+D++SLG+I + +I PFD E K I E P +D K + + +
Sbjct: 207 TYDGFKIDIWSLGVILYTLITGYLPFDDDDE----AKTKWKIVNEEPK-YDAKVIPDDAR 261
Query: 968 KIIKLLLDHDPVRRPTASALLR 989
+I LL +P RP+ S +LR
Sbjct: 262 DLISRLLAKNPGERPSLSQVLR 283
>YLR113w [T] KOG0660 Mitogen-activated protein kinase
Length = 435
Score = 80.9 bits (198), Expect = 2e-14
Identities = 55/152 (36%), Positives = 80/152 (52%), Gaps = 21/152 (13%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
L+ L+ T L Q +Y+ QIL L Y+HS G+IHRDLKP NI I+E+ ++KI DFG
Sbjct: 107 LHRLLQTRPLEKQFVQYF--LYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFG 164
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ +Q Q +T + T Y A EI+ + Y+ +VD++S G IF
Sbjct: 165 LAR-IQDPQ----------------MTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIF 207
Query: 928 FEMI--YPFDTGMERVNVIKKLRNIDVEFPSD 957
EMI P G + V+ + ++ P D
Sbjct: 208 AEMIEGKPLFPGKDHVHQFSIITDLLGSPPKD 239
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 80.9 bits (198), Expect = 2e-14
Identities = 72/239 (30%), Positives = 116/239 (48%), Gaps = 33/239 (13%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
+ L++ +EY E L++L+ ++E FRQI+ +SY H+ GI+HRDLKP N+
Sbjct: 100 NNLYLILEYAEKGELFNLLVDHGPLPEREAI-NCFRQIIIGISYCHALGIVHRDLKPENL 158
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+D NIKI DFG+A +Q D L TS GS Y A EI++
Sbjct: 159 LLDSFYNIKIADFGMAA-LQTDADLLE----TSCGSPH----------YAAPEIVSGLPY 203
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
D++S G+I F ++ PFD V +++ K++ E P+D + + + +
Sbjct: 204 EGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISR--DAQDL 261
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQP 1028
I +L DP +R +L P+ + + IK++ K+I D REN + P
Sbjct: 262 IGKILVVDPRQRIKIRDILSH---PLLKKYQTIKDS-KSIKD-------LPRENTYLYP 309
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 80.9 bits (198), Expect = 2e-14
Identities = 62/197 (31%), Positives = 96/197 (48%), Gaps = 24/197 (12%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
L+D I E ++E R F+QI+ A+ Y H I+HRDLKP N+ +D++ N+KI DFG
Sbjct: 118 LFDYI-VEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFG 176
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
L+ N+ + L+ TS GS Y A E+I +VD++S GI+
Sbjct: 177 LS-NIMTDGNFLK----TSCGSPN----------YAAPEVINGKLYAGPEVDVWSCGIVL 221
Query: 928 FEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTA 984
+ M+ PFD N+ KK+ + P D + +I+ ++ DP++R T
Sbjct: 222 YVMLVGRLPFDDEF-IPNLFKKVNSCVYVMP----DFLSPGAQSLIRRMIVADPMQRITI 276
Query: 985 SALLRSGWVPVKNQDEL 1001
+ R W V D L
Sbjct: 277 QEIRRDPWFNVNLPDYL 293
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 80.9 bits (198), Expect = 2e-14
Identities = 59/196 (30%), Positives = 95/196 (48%), Gaps = 12/196 (6%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQK-EEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
L+ + N L D I+ N+ +Y+ I++++ Y+H +G+IHRDLKP NI
Sbjct: 173 LYFVLSLARNGELLDYINKLGRFNEICAQYYAAL--IVDSIDYMHGRGVIHRDLKPENIL 230
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+D++ KI DFG AK + S + D+ + S +GTA YV+ E++ S
Sbjct: 231 LDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVL-SDKIA 289
Query: 915 NEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
D+++ G I F+M+ PF G E + + + ++ E P D D +IK
Sbjct: 290 GTASDIWAFGCILFQMLAGKPPFVAGNEYL-TFQSILHLSYEIPPDISD----VASDLIK 344
Query: 972 LLLDHDPVRRPTASAL 987
LL DP R T +
Sbjct: 345 KLLVLDPKDRLTVDEI 360
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 80.9 bits (198), Expect = 2e-14
Identities = 55/209 (26%), Positives = 97/209 (46%), Gaps = 29/209 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+++ ++ ME C L I+ E ++ E R RQ++ A+ ++H G++HRDLK N
Sbjct: 133 ENSYYLVMELCPGGNLMHKIY-EKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIEN 191
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE NIK+ DFGL+ I G S ++ G+ Y A E++ +
Sbjct: 192 LLLDEDNNIKLIDFGLSNCAGI------------LGYSDPFSTQCGSPAYAAPELL-ARK 238
Query: 913 NYNEKVDMYSLGIIFFEM--------IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
Y K+D++S+G+ + M + PF ++ K N P+ +
Sbjct: 239 KYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMN---PLPTQLSTGAI- 294
Query: 965 TEKKIIKLLLDHDPVRRPTASALLRSGWV 993
++ LL+ DPV+RP L + W+
Sbjct: 295 ---SFLRSLLEPDPVKRPNIQQALANRWL 320
>Hs5031975 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 591
Score = 80.9 bits (198), Expect = 2e-14
Identities = 63/204 (30%), Positives = 103/204 (49%), Gaps = 36/204 (17%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ ME+ E L D++ +N +E+ + +L+ALS +H+QG+IHRD+K +I +
Sbjct: 391 LWVVMEFLEGGALTDIVTHTRMN--EEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILL 448
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+K+ DFG Q+S++ RR S +GT ++A E+I S Y
Sbjct: 449 THDGRVKLSDFGFC--AQVSKEVPRRKSL------------VGTPYWMAPELI-SRLPYG 493
Query: 916 EKVDMYSLGIIFFEMI---YPF-------DTGMERVNVIKKLRNIDVEFPSDFDDKKLHT 965
+VD++SLGI+ EM+ P+ M R N+ +L+N+ PS
Sbjct: 494 PEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPS--------- 544
Query: 966 EKKIIKLLLDHDPVRRPTASALLR 989
K + LL DP +R TA+ LL+
Sbjct: 545 LKGFLDRLLVRDPAQRATAAELLK 568
>CE07737 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1418
Score = 80.9 bits (198), Expect = 2e-14
Identities = 70/231 (30%), Positives = 109/231 (46%), Gaps = 18/231 (7%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S + I MEYC TL + H + +Y +L A+ Y+HS IIHRD+KP NI
Sbjct: 1192 SDVIIFMEYCSQGTLERICHGKMDLKMVRQYTN---SLLRAVQYLHSHKIIHRDIKPANI 1248
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
F+D+ +K+GDFG + + + T+ + T+AG+ + I + E S+
Sbjct: 1249 FLDKCTVLKLGDFGCSSRL-VESSTVYGEFQTTAGTPQFMAPEI-YSYGEKDETTGSYSG 1306
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKL--RNIDVEFPSDFDDKKLHTEKK 968
Y VD+++LG M+ PF+ G R + L R +P D DK+ K+
Sbjct: 1307 YGRSVDIWALGATVVNMMTGKVPFE-GQTRHQIAFALCFRKQKPTYP-DIADKRPDV-KR 1363
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDE-----LIKEALKNISDPSS 1014
+ P RPTA+ LL++ + V DE ++ K+ S PSS
Sbjct: 1364 FFDNCFEFLPNDRPTAAELLQTTFANVNITDENHIPDYQSQSSKDKSSPSS 1414
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 80.9 bits (198), Expect = 2e-14
Identities = 65/212 (30%), Positives = 110/212 (51%), Gaps = 30/212 (14%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPM 851
+ L++ MEY L+ L+ +L E+ R++ +++ AL Y+HS IIHRDLKP
Sbjct: 824 RENLYLVMEYLNGGDLFSLLR--NLGCLDEDMARIYIAEVVLALEYLHSVNIIHRDLKPD 881
Query: 852 NIFIDESRNIKIGDFGLAKNVQI-SQDTLRRDSFTSAGSSGDLT---------------- 894
N+ I++ +IK+ DFGL+K I S D L +S S G+SG
Sbjct: 882 NLLINQDGHIKLTDFGLSKVGLINSTDDLSGES--SLGNSGFFAEDGSKAQHSQGKDSRK 939
Query: 895 --SAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRN 949
+ +GT Y+A EI+ G + + D +S+G+I FE+ I PF+ + + + + N
Sbjct: 940 KHAVVGTPDYLAPEILLGMG-HGKTADWWSVGVILFEVLVGIPPFNAETPQ-QIFENIIN 997
Query: 950 IDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRR 981
D+ +P + ++ + +I LL +PV+R
Sbjct: 998 RDIPWP-NVPEEISYEAHDLINKLLTENPVQR 1028
>At1g63700 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 883
Score = 80.9 bits (198), Expect = 2e-14
Identities = 62/201 (30%), Positives = 97/201 (47%), Gaps = 22/201 (10%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPMNIF 854
L+I +EY ++Y L+ + E R + +QIL L+Y+H++ +HRD+K NI
Sbjct: 475 LYIYLEYVSGGSIYKLL--QEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANIL 532
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+D +K+ DFG+AK++ SG L S G+ ++A E+I +
Sbjct: 533 VDPHGRVKVADFGMAKHI--------------TAQSGPL-SFKGSPYWMAPEVIKNSNGS 577
Query: 915 NEKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
N VD++SLG EM P + E V + K+ N E P D D K ++
Sbjct: 578 NLAVDIWSLGCTVLEMATTKPPWSQYEGVPAMFKIGN-SKELP-DIPDHLSEEGKDFVRK 635
Query: 973 LLDHDPVRRPTASALLRSGWV 993
L +P RPTA+ LL +V
Sbjct: 636 CLQRNPANRPTAAQLLDHAFV 656
>HsM5454174 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 80.5 bits (197), Expect = 2e-14
Identities = 61/203 (30%), Positives = 105/203 (51%), Gaps = 21/203 (10%)
Query: 793 KST-LFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKP 850
KST L+I MEY + DL+ L +E Y + R+IL+ L Y+HS+ IHRD+K
Sbjct: 87 KSTKLWIIMEYLGGGSALDLLKPGPL---EETYIATILREILKGLDYLHSERKIHRDIKA 143
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
N+ + E ++K+ DFG+A Q++ ++R++F +GT ++A E+I
Sbjct: 144 ANVLLSEQGDVKLADFGVAG--QLTDTQIKRNTF------------VGTPFWMAPEVI-K 188
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
Y+ K D++SLGI E+ + ++ ++ L I P + + K+ +
Sbjct: 189 QSAYDFKADIWSLGITAIELAKGEPPNSD-LHPMRVLFLIPKNSPPTLEGQHSKPFKEFV 247
Query: 971 KLLLDHDPVRRPTASALLRSGWV 993
+ L+ DP RPTA LL+ ++
Sbjct: 248 EACLNKDPRFRPTAKELLKHKFI 270
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 414
Score = 80.5 bits (197), Expect = 2e-14
Identities = 67/258 (25%), Positives = 118/258 (44%), Gaps = 35/258 (13%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKE-EYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
S + + +EY ++D + KE + RL RQILE + ++H++ ++H DLKP N
Sbjct: 132 SEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQN 191
Query: 853 IFIDESR---NIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
I + +IKI DFGL++ ++ +S +L +GT YVA EI+
Sbjct: 192 ILLTSESPLGDIKIVDFGLSRILK---------------NSEELREIMGTPEYVAPEIL- 235
Query: 910 SHGNYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
S+ + DM+S+G++ + M I PF G ++ + +++ + + D +
Sbjct: 236 SYDPISMATDMWSIGVLTYVMLTGISPF-LGNDKQETFLNISQMNLSYSEEEFDVLSESA 294
Query: 967 KKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFT 1026
I+ LL P R TA L+ W+ +I +PS ++ + E
Sbjct: 295 VDFIRTLLVKKPEDRATAEECLKHPWL-----------TQSSIQEPSFRMEKALEEANAL 343
Query: 1027 QPYHLSSDILFDLSRSDT 1044
Q H +I D +S+T
Sbjct: 344 QEGHSVPEINSDTDKSET 361
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 80.5 bits (197), Expect = 2e-14
Identities = 62/208 (29%), Positives = 104/208 (49%), Gaps = 30/208 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQ---KEEYWRLFRQILEALSYIHSQG-----IIH 845
+TL+I MEYCE L +I + Q +E R+ Q+ AL H + ++H
Sbjct: 80 TTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLH 139
Query: 846 RDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVAS 905
RDLKP N+F+D +N+K+GDFGLA+ ++ DT +F +GT Y++
Sbjct: 140 RDLKPANVFLDGKQNVKLGDFGLAR--ILNHDTSFAKTF------------VGTPYYMSP 185
Query: 906 EIITSHGNYNEKVDMYSLGIIFFEM--IYPFDTGMERVNVIKKLRNIDV-EFPSDFDDKK 962
E + + +YNEK D++SLG + +E+ + P T + + K+R P + D+
Sbjct: 186 EQM-NRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRYSDEL 244
Query: 963 LHTEKKIIKLLLDHDPVRRPTASALLRS 990
+II +L+ RP+ +L +
Sbjct: 245 ----NEIITRMLNLKDYHRPSVEEILEN 268
>Hs21361358 [T] KOG0201 Serine/threonine protein kinase
Length = 426
Score = 80.5 bits (197), Expect = 2e-14
Identities = 61/203 (30%), Positives = 105/203 (51%), Gaps = 21/203 (10%)
Query: 793 KST-LFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKP 850
KST L+I MEY + DL+ L +E Y + R+IL+ L Y+HS+ IHRD+K
Sbjct: 87 KSTKLWIIMEYLGGGSALDLLKPGPL---EETYIATILREILKGLDYLHSERKIHRDIKA 143
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
N+ + E ++K+ DFG+A Q++ ++R++F +GT ++A E+I
Sbjct: 144 ANVLLSEQGDVKLADFGVAG--QLTDTQIKRNTF------------VGTPFWMAPEVI-K 188
Query: 911 HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKII 970
Y+ K D++SLGI E+ + ++ ++ L I P + + K+ +
Sbjct: 189 QSAYDFKADIWSLGITAIELAKGEPPNSD-LHPMRVLFLIPKNSPPTLEGQHSKPFKEFV 247
Query: 971 KLLLDHDPVRRPTASALLRSGWV 993
+ L+ DP RPTA LL+ ++
Sbjct: 248 EACLNKDPRFRPTAKELLKHKFI 270
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 80.5 bits (197), Expect = 2e-14
Identities = 64/193 (33%), Positives = 100/193 (51%), Gaps = 13/193 (6%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPMNIF 854
L + MEY E L+ +S E RL+ + + A+ Y+HS GI+HRDLKP N+
Sbjct: 431 LCMLMEYVEGGDCAALL--KSAGTLPVELVRLYVAETILAIEYLHSYGIVHRDLKPDNLL 488
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDL--TSAIGTALYVASEIITSHG 912
I +IK+ DFGL+K +++ TL + + + + GT Y+A E+I G
Sbjct: 489 ITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCGTPEYIAPEVILRRG 548
Query: 913 NYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE-KK 968
Y + VD ++LGII +E I PF G + K+ + DVE+P +D+ L E
Sbjct: 549 -YGKPVDWWALGIILYEFLVGIVPF-FGETPEALFSKVISEDVEYPE--EDEALPPEAAD 604
Query: 969 IIKLLLDHDPVRR 981
+ + LL+ +P R
Sbjct: 605 LCRRLLEKNPAER 617
>At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 601
Score = 80.5 bits (197), Expect = 2e-14
Identities = 60/217 (27%), Positives = 103/217 (46%), Gaps = 24/217 (11%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
++I ME CE L D I + +E+ + QIL +++ H QG++HRDLKP N
Sbjct: 225 VYIVMELCEGGELLDRILSRGGKYTEEDAKTVMIQILNVVAFCHLQGVVHRDLKPENFLF 284
Query: 856 ---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+++ +K DFGL+ D +R D L +G+A YVA E++ H
Sbjct: 285 TSKEDTSQLKAIDFGLS-------DYVRPDE--------RLNDIVGSAYYVAPEVL--HR 327
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+Y+ + D++S+G+I + ++ PF E + + + D F +
Sbjct: 328 SYSTEADIWSVGVIVYILLCGSRPFWARTES-GIFRAVLKADPSFDDPPWPLLSSEARDF 386
Query: 970 IKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEAL 1006
+K LL+ DP +R TA+ L W+ N ++ + L
Sbjct: 387 VKRLLNKDPRKRLTAAQALSHPWIKDSNDAKVPMDIL 423
>At3g04810 [R] KOG0589 Serine/threonine protein kinase
Length = 606
Score = 80.5 bits (197), Expect = 2e-14
Identities = 69/237 (29%), Positives = 115/237 (48%), Gaps = 36/237 (15%)
Query: 802 YCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRN 860
YC+ + + I T ++ +E+ + QIL AL Y+H+ I+HRD+K NIF+ + ++
Sbjct: 83 YCKGGDMAEAIKKTNGVHFTEEKLCKWLVQILLALEYLHANHILHRDVKCSNIFLTKDQD 142
Query: 861 IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDM 920
I++GDFGLAK L D S S +GT Y+ E++ Y K D+
Sbjct: 143 IRLGDFGLAK-------VLTSDDLAS--------SVVGTPSYMCPELLADI-PYGSKSDI 186
Query: 921 YSLGIIFFEM--IYPFDTGMERVNVIKKL-RNIDVEFPSDFDDKKLHTEKKIIKLLLDHD 977
+SLG +EM + P + +I ++ R+I P+ + + ++K +L +
Sbjct: 187 WSLGCCMYEMTAMKPAFKAFDMQGLINRINRSIVPPLPAQYS----AAFRGLVKSMLRKN 242
Query: 978 PVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSS-------PWQQQVRENLFTQ 1027
P RP+A+ LLR + Q + K LK ++DP S P + R N F +
Sbjct: 243 PELRPSAAELLRQPLL----QPYIQKIHLK-VNDPGSNVLPAQWPESESARRNSFPE 294
>At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase
(MAP4K) germinal center kinase family
Length = 836
Score = 80.5 bits (197), Expect = 2e-14
Identities = 95/382 (24%), Positives = 166/382 (42%), Gaps = 55/382 (14%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L+I MEYC ++ DL++ ++ + + R+ L+ L+Y+HS +HRD+K NI +
Sbjct: 320 LWIVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILL 379
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
E +K+GDFG+A Q+++ +R++F IGT ++A E+I Y+
Sbjct: 380 TEQGEVKLGDFGVA--AQLTRTMSKRNTF------------IGTPHWMAPEVI-QENRYD 424
Query: 916 EKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHT--EKKIIKLL 973
KVD+++LG+ EM V+ ++ L I +E +DK+ + +
Sbjct: 425 GKVDVWALGVSAIEMAEGLPP-RSSVHPMRVLFMISIEPAPMLEDKEKWSLVFHDFVAKC 483
Query: 974 LDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQPYHLSS 1033
L +P RPTA+ +L+ +V E K +S P +Q+R + Q + +
Sbjct: 484 LTKEPRLRPTAAEMLKHKFV------ERCKTGASAMS-PKIEKSRQIRATMALQAQSVVA 536
Query: 1034 DILFDLSRSDTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPIYSTQNVYEVL 1093
L D S L + +E+ G ++PP +AP+ ST N +
Sbjct: 537 PSLEDTS---------TLGPKSSEEL-------GITVPSKPPQNSTEAPLTSTLNRQHI- 579
Query: 1094 DRGGSVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSESTHSSTE--PRKFGEVDF 1151
G +VL + + + T + + R ES+ S E PR+F
Sbjct: 580 -TGNTVLAGEGG---DFGTMIVHGEDETEESDSRSQLVREKESSSSQFEGVPREFP---- 631
Query: 1152 DIISNSSTDSAVHDAECLKVVD 1173
DS +HD + +D
Sbjct: 632 ---GEELPDSWIHDKKKPPAID 650
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 80.5 bits (197), Expect = 2e-14
Identities = 60/206 (29%), Positives = 101/206 (48%), Gaps = 32/206 (15%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S +F+ MEY L+D I Q+ + R F+QI+ + Y H I+HRDLKP N+
Sbjct: 99 SDIFMIMEYVSGGELFDYIVKHG-KLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENL 157
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+D + ++KI DFGL+ N+ + + LR TS GS Y A E+I+
Sbjct: 158 LLDHNMHVKIADFGLS-NMMLDGEFLR----TSCGSPN----------YAAPEVISGKLY 202
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERV-NVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD++S G+I + ++ PFD E V + +K+++ P + K++
Sbjct: 203 AGPEVDIWSCGVILYALLCGTLPFDD--EHVPTLFRKIKSGIFPIPE-------YLNKQV 253
Query: 970 IKL---LLDHDPVRRPTASALLRSGW 992
+ L +L DP++R + + W
Sbjct: 254 VNLVCQMLQVDPLKRANIEEIKKHEW 279
>YBR274w [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 527
Score = 80.1 bits (196), Expect = 3e-14
Identities = 60/212 (28%), Positives = 106/212 (49%), Gaps = 29/212 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTE-SLNNQKEEYWRLFRQILEALSYIHSQ-GIIHRDLKP 850
K ++I +E + L+D I + +++ +++ F+Q++ A++Y+H + G+ HRD+KP
Sbjct: 88 KEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFY--FQQLVSAINYLHVECGVAHRDIKP 145
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
NI +D++ N+K+ DFGLA + TLR G+ Y+A E++ S
Sbjct: 146 ENILLDKNGNLKLADFGLASQFRRKDGTLRVS-----------MDQRGSPPYMAPEVLYS 194
Query: 911 -HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFD--------DK 961
G Y ++ D++S+GI+ F ++ TG + L N D F + D K
Sbjct: 195 EEGYYADRTDIWSIGILLFVLL----TGQTPWE-LPSLENEDFVFFIENDGNLNWGPWSK 249
Query: 962 KLHTEKKIIKLLLDHDPVRRPTASALLRSGWV 993
T +++ +L DP +R T AL WV
Sbjct: 250 IEFTHLNLLRKILQPDPNKRVTLKALKLHPWV 281
>SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase
Length = 349
Score = 80.1 bits (196), Expect = 3e-14
Identities = 53/137 (38%), Positives = 75/137 (54%), Gaps = 21/137 (15%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
L+ L+ + L Q +Y+ QIL L ++HS G+IHRDLKP NI I+E+ ++KI DFG
Sbjct: 104 LHRLLTSRPLETQFIQYF--LYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFG 161
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ +Q Q +T + T Y A EI+ + YN +VD++S G IF
Sbjct: 162 LAR-IQDPQ----------------MTGYVSTRYYRAPEIMLTWQKYNVEVDIWSAGCIF 204
Query: 928 FEMI--YPFDTGMERVN 942
EMI P G + VN
Sbjct: 205 AEMIEGKPLFPGRDHVN 221
>CE24971 [T] KOG0660 Mitogen-activated protein kinase
Length = 444
Score = 80.1 bits (196), Expect = 3e-14
Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 23/177 (12%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
LY L+ T+ L+N Y+ QIL L YIHS ++HRDLKP N+ ++ + ++KI DFG
Sbjct: 183 LYKLLKTQKLSNDHVCYF--LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG 240
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ D +G LT + T Y A EI+ + Y + +D++S+G I
Sbjct: 241 LARVTDPQTD-----------HTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCIL 289
Query: 928 FEM-----IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLL-LDHDP 978
EM ++P ++++N+I + V PS+ D + + +K L+ L H P
Sbjct: 290 AEMLSNRPLFPGKHYLDQLNLILAV----VGSPSNADLQCIINDKARSYLISLPHKP 342
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 80.1 bits (196), Expect = 3e-14
Identities = 65/223 (29%), Positives = 109/223 (48%), Gaps = 28/223 (12%)
Query: 801 EYCENRTLYDLIHTESLNNQKEEYWRL-FRQILEALSYIHSQGIIHRDLKPMNIFIDESR 859
EYC L L + + KEE + FRQ++ AL+++ S I+HRDLK NIF+D+
Sbjct: 149 EYCAGGDL--LRKMKDIVAMKEEDAKFTFRQLIAALTHLQSYNIVHRDLKCENIFMDKHG 206
Query: 860 NIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVD 919
N+K+GDFG ++ ++ + SG + G+ YVA EI VD
Sbjct: 207 NVKLGDFGFSRILKPGE------------KSG---TFCGSRAYVAPEIFRGREYSGNAVD 251
Query: 920 MYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDH 976
++S G+I + M+ PFD R + ++L + ++FP + ++ ++++L H
Sbjct: 252 VWSTGVILYIMLAGSMPFDDRDPRKMIERQLAH-KIKFPKSC-TSSVFSKALVLEILQPH 309
Query: 977 DPVRRPTASALLRSGWVPVK----NQDELIKEALKNISDPSSP 1015
P RPT A+ S W+ + +E K I P++P
Sbjct: 310 AP-NRPTYKAICESEWLRTQPYYMKPNEPPKVLATRIVSPATP 351
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 80.1 bits (196), Expect = 3e-14
Identities = 60/202 (29%), Positives = 100/202 (48%), Gaps = 26/202 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESL--NNQKEEYWR------LFRQILEALSYIHSQGIIHRD 847
L I M+Y E TL LI+ + ++ EY+ F QIL AL+++H + I+HRD
Sbjct: 78 LGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRD 137
Query: 848 LKPMNIFIDESRNI-KIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASE 906
LKP NI ++ + + K+ DFG++K + G+ ++ IGT Y++ E
Sbjct: 138 LKPQNILMNRRKTVLKLSDFGISKEL---------------GTKSAASTVIGTPNYLSPE 182
Query: 907 IITSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
I S YN+K DM+SLG + +E++ + + N+ + I + D +
Sbjct: 183 ICESR-PYNQKSDMWSLGCVLYELL-QLERAFDGENLPAIVMKITRSKQNPLGDHVSNDV 240
Query: 967 KKIIKLLLDHDPVRRPTASALL 988
K +++ LL +RP S LL
Sbjct: 241 KMLVENLLKTHTDKRPDVSQLL 262
>CE01583 [T] KOG0660 Mitogen-activated protein kinase
Length = 376
Score = 80.1 bits (196), Expect = 3e-14
Identities = 57/177 (32%), Positives = 92/177 (51%), Gaps = 23/177 (12%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
LY L+ T+ L+N Y+ QIL L YIHS ++HRDLKP N+ ++ + ++KI DFG
Sbjct: 115 LYKLLKTQKLSNDHVCYF--LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG 172
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ D +G LT + T Y A EI+ + Y + +D++S+G I
Sbjct: 173 LARVTDPQTD-----------HTGFLTEYVATRWYRAPEIMLNSKGYTKSIDVWSVGCIL 221
Query: 928 FEM-----IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLL-LDHDP 978
EM ++P ++++N+I + V PS+ D + + +K L+ L H P
Sbjct: 222 AEMLSNRPLFPGKHYLDQLNLILAV----VGSPSNADLQCIINDKARSYLISLPHKP 274
>At4g10730 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 693
Score = 80.1 bits (196), Expect = 3e-14
Identities = 53/174 (30%), Positives = 90/174 (51%), Gaps = 23/174 (13%)
Query: 827 LFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLR-RDSFT 885
+ ++ L+AL Y+H QG IHRD+K NI +D++ IK+GDFG++ + + D R R++F
Sbjct: 130 MLKETLKALDYLHRQGHIHRDVKAGNILLDDTGEIKLGDFGVSACLFDNGDRQRARNTF- 188
Query: 886 SAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVN 942
+GT ++A E++ YN K D++S GI E+ + PF
Sbjct: 189 -----------VGTPCWMAPEVLQPGSGYNSKADIWSFGITALELAHGHAPFSKYPPMKV 237
Query: 943 VIKKLRN----IDVEFPSDFDDKK---LHTEKKIIKLLLDHDPVRRPTASALLR 989
++ ++N +D + F K + K+++ L L D +RPTA LL+
Sbjct: 238 LLMTIQNAPPGLDYDRDKKFSKKMSSCAQSFKELVALCLVKDQTKRPTAEKLLK 291
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 80.1 bits (196), Expect = 3e-14
Identities = 58/198 (29%), Positives = 95/198 (47%), Gaps = 18/198 (9%)
Query: 793 KSTLFIQMEYCENRTLYDLIH-TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
K + I YCE + +I + + +E+ R Q+L A+ Y+H+ ++HRDLK
Sbjct: 84 KDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCS 143
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
NIF+ + +++GDFGLAK L +D S S +GT Y+ E++
Sbjct: 144 NIFLTKENEVRLGDFGLAK-------LLGKDDLAS--------SMVGTPNYMCPELLADI 188
Query: 912 GNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
Y K D++SLG FE + + ++ + I+ S + K++IK
Sbjct: 189 -PYGYKSDIWSLGCCMFE-VAAHQPAFKAPDMAALINKINRSSLSPLPVMYSSSLKRLIK 246
Query: 972 LLLDHDPVRRPTASALLR 989
+L +P RPTA+ LLR
Sbjct: 247 SMLRKNPEHRPTAAELLR 264
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 80.1 bits (196), Expect = 3e-14
Identities = 62/246 (25%), Positives = 112/246 (45%), Gaps = 30/246 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + +KE + FRQI+ A+ Y H + IIHRDLK N
Sbjct: 220 EKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVK-FRQIVSAVQYCHQKRIIHRDLKAEN 278
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + FT L + G+ Y A E+
Sbjct: 279 LLLDSELNIKIADFGFS------------NEFTPGSK---LDTFCGSPPYAAPELFQGKK 323
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGM---ERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
+VD++SLG+I + ++ PFD R V++ I +D ++
Sbjct: 324 YDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCEN------ 377
Query: 967 KKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFT 1026
+++ L +P +R + ++ W+ + +++ +K ++ +D + P + E L
Sbjct: 378 --LLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLADPKRIGKTEALVA 435
Query: 1027 QPYHLS 1032
Y+ S
Sbjct: 436 MGYNRS 441
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 79.7 bits (195), Expect = 4e-14
Identities = 64/200 (32%), Positives = 102/200 (51%), Gaps = 17/200 (8%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTE-SLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
+S+L+ +EY N L+ SL+ Y+ QI++A+ Y+HS GIIHRD+KP
Sbjct: 250 ESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAA--QIIDAIDYLHSNGIIHRDIKPE 307
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT-S 910
NI +D IK+ DFG AK + + +++ + + + S S +GTA YV+ E++ S
Sbjct: 308 NILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRS---KSFVGTAEYVSPELLNDS 364
Query: 911 HGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
+Y + D+++ G I F+MI PF E + +K+ + F F K
Sbjct: 365 FTDY--RCDIWAFGCILFQMIAGKPPFKATNEYL-TFQKVMKVQYAFTPGFPLIIRDLVK 421
Query: 968 KIIKLLLDHDPVRRPTASAL 987
KI+ LD RR T S +
Sbjct: 422 KILVKNLD----RRLTISQI 437
>Hs4506401 [T] KOG0193 Serine/threonine protein kinase RAF
Length = 648
Score = 79.7 bits (195), Expect = 4e-14
Identities = 45/141 (31%), Positives = 76/141 (52%), Gaps = 14/141 (9%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L I ++CE +LY +H + Q + + RQ + + Y+H++ IIHRD+K N
Sbjct: 414 KDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNN 473
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
IF+ E +KIGDFGLA T++ + S + G+ L++A E+I
Sbjct: 474 IFLHEGLTVKIGDFGLA--------TVK----SRWSGSQQVEQPTGSVLWMAPEVIRMQD 521
Query: 913 N--YNEKVDMYSLGIIFFEMI 931
N ++ + D+YS GI+ +E++
Sbjct: 522 NNPFSFQSDVYSYGIVLYELM 542
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 79.7 bits (195), Expect = 4e-14
Identities = 52/163 (31%), Positives = 89/163 (53%), Gaps = 23/163 (14%)
Query: 825 WRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSF 884
W+ F Q+ AL ++HS+ ++HRD+KP N+FI + +K+GD GL + F
Sbjct: 139 WKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGR------------FF 186
Query: 885 TSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI---YPF-DTGMER 940
+S ++ S +GT Y++ E I +G YN K D++SLG + +EM PF M
Sbjct: 187 SSKTTAAH--SLVGTPYYMSPERIHENG-YNFKSDIWSLGCLLYEMAALQSPFYGDKMNL 243
Query: 941 VNVIKKLRNIDV-EFPSDFDDKKLHTEKKIIKLLLDHDPVRRP 982
++ KK+ D PSD ++L ++++ + ++ DP +RP
Sbjct: 244 YSLCKKIEQCDYPPLPSDHYSEEL---RQLVNMCINPDPEKRP 283
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 79.7 bits (195), Expect = 4e-14
Identities = 62/255 (24%), Positives = 116/255 (45%), Gaps = 41/255 (16%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ TL++ MEY ++D + + +KE + FRQI+ A+ Y H + I+HRDLK N
Sbjct: 128 EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAK-FRQIVSAVHYCHQKNIVHRDLKAEN 186
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D NIKI DFG + + + D+F G+ Y A E+
Sbjct: 187 LLLDAEANIKIADFGFSNEFTLGS---KLDTF------------CGSPPYAAPELFQGKK 231
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFD---TGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
+VD++SLG+I + ++ PFD R V++ + +D +
Sbjct: 232 YDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCE------- 284
Query: 967 KKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIK---EALKNISDPS--------SP 1015
I++ L +P +R T +++ W+ + + E +K E ++ D
Sbjct: 285 -SILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGY 343
Query: 1016 WQQQVRENLFTQPYH 1030
+++++E+L +Q Y+
Sbjct: 344 TREEIKESLTSQKYN 358
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 79.7 bits (195), Expect = 4e-14
Identities = 54/200 (27%), Positives = 99/200 (49%), Gaps = 25/200 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
++I +E C R+L +L + E + QI++ + Y+H IIHRD+K N+F+
Sbjct: 111 VYITLELCARRSLMELHKRRKAVTEPEARY-FTHQIVDGVLYLHDLNIIHRDMKLGNLFL 169
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
++ +KIGDFGLA T+ + GT Y+A E++ G ++
Sbjct: 170 NDDLVVKIGDFGLA---------------TTVNGDERKKTLCGTPNYIAPEVLNKAG-HS 213
Query: 916 EKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+VD++++G I + +++ PF++ ++R+ + PS +I+
Sbjct: 214 FEVDIWAVGCILYILLFGQPPFES-KSLEETYSRIRHNNYTIPS----IATQPAASLIRK 268
Query: 973 LLDHDPVRRPTASALLRSGW 992
+LD +P RRPTA + R G+
Sbjct: 269 MLDPEPTRRPTAKQVQRDGF 288
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 79.7 bits (195), Expect = 4e-14
Identities = 63/258 (24%), Positives = 109/258 (41%), Gaps = 48/258 (18%)
Query: 795 TLFIQMEYCENRTLYDLIHTESLNNQKEEYWR-LFRQILEALSYIHSQGIIHRDLKPMNI 853
TL++ MEY L+D H +E R +FRQ++ A+ Y HS+ ++HRDLK N+
Sbjct: 169 TLYLVMEYASRGELFD--HLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENL 226
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+D+ NIKI DFG + L + G+ Y A E+
Sbjct: 227 LLDQHMNIKIADFGFGNTFD---------------PNAQLETFCGSPPYAAPELFMGRKY 271
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGM---ERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
+VD +SLG++ + ++ PFD G R V++ + D ++
Sbjct: 272 AGPEVDAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKYRVPYYISMDCEN------- 324
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV----------------PVKNQDELIKEALKNISD 1011
+++ L +P +R + SA++ W+ P++ QD + L ++
Sbjct: 325 -LMRKFLVLNPAKRTSLSAVMSDKWINLGHDESDRLRPFREKPMELQDAARFDLLMSMGH 383
Query: 1012 PSSPWQQQVRENLFTQPY 1029
+Q V+ LF Y
Sbjct: 384 KRRDVEQSVKGQLFDDIY 401
>7290147 [T] KOG0583 Serine/threonine protein kinase
Length = 291
Score = 79.7 bits (195), Expect = 4e-14
Identities = 49/141 (34%), Positives = 77/141 (53%), Gaps = 22/141 (15%)
Query: 795 TLFIQMEYCENRTLYDLIH-----TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLK 849
T+ I MEY N TL D+I T +N +E FR ++ L Y+H + +IHRD+K
Sbjct: 82 TVNIVMEYVPNGTLRDVIQQLPSGTGGVN--QERLMGYFRDMVVGLEYLHIRCVIHRDIK 139
Query: 850 PMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
P N+ +D + +KI DFG+A NV S L + +GT +Y+A E ++
Sbjct: 140 PENMLLDANDRVKIADFGIA-NVH--------------APSTQLQAGMGTPMYMAPEAMS 184
Query: 910 SHGNYNEKVDMYSLGIIFFEM 930
S G + K D++SLG++ +E+
Sbjct: 185 SQGKVDFKSDVWSLGLVLYEL 205
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 79.3 bits (194), Expect = 5e-14
Identities = 63/199 (31%), Positives = 102/199 (50%), Gaps = 19/199 (9%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMNIF 854
L++ MEYC + + T E+ R + ++ AL Y+H G I+RDLKP NI
Sbjct: 569 LYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEVTAALEYLHLLGFIYRDLKPENIL 628
Query: 855 IDESRNIKIGDFGL---AKNVQI------SQDTLRRDSFTSAGSSGDLTSAIGTALYVAS 905
+ +S +I + DF L AK+ ++ +Q TL S G S +GT Y+A
Sbjct: 629 LHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDTKICSDGFR--TNSFVGTEEYIAP 686
Query: 906 EIITSHGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI---DVEFPSDFDDKK 962
E+I +G + VD ++LGI+ +EM++ F T + N + NI +V FP++ + +
Sbjct: 687 EVIRGNG-HTAAVDWWTLGILIYEMLFGF-TPFKGDNTNETFTNILKNEVSFPNNNEISR 744
Query: 963 LHTEKKIIKLLLDHDPVRR 981
T K +IK LL + +R
Sbjct: 745 --TCKDLIKKLLTKNESKR 761
>Hs4826878 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 527
Score = 79.3 bits (194), Expect = 5e-14
Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 29/192 (15%)
Query: 827 LFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTS 886
+ R++LE L Y+H G IHRD+K NI + E +++I DFG++ +F +
Sbjct: 126 ILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVS-------------AFLA 172
Query: 887 AGSSGDLT------SAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEM---IYPFDTG 937
G GD+T + +GT ++A E++ Y+ K D++S GI E+ P+
Sbjct: 173 TG--GDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKY 230
Query: 938 MERVNVIKKLRNIDVEFPSDFDDKKL-----HTEKKIIKLLLDHDPVRRPTASALLRSGW 992
++ L+N + DK++ + +K+I L L DP +RPTA+ LLR +
Sbjct: 231 PPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKF 290
Query: 993 VPVKNQDELIKE 1004
E ++E
Sbjct: 291 FQKAKNKEFLQE 302
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 79.3 bits (194), Expect = 5e-14
Identities = 60/209 (28%), Positives = 98/209 (46%), Gaps = 28/209 (13%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN-IFI 855
F+ ME L+D + + ++ E + + R+++ ALS++H G++HRDLKP N +F
Sbjct: 495 FLVMELLNGGELFDALRKKKHFSETEASY-IMRKLVSALSHMHDLGVVHRDLKPENLLFT 553
Query: 856 DESRN--IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
DE+ N IKI DFG A+ L+ FT L+ + +
Sbjct: 554 DENDNLEIKIIDFGFARLKPPDNQPLKTPCFT---------------LHSCRPELLNQNG 598
Query: 914 YNEKVDMYSLGIIFFEMI---YPFD------TGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
Y+E D++SLG+I + M+ PF T V ++KK++ D F +
Sbjct: 599 YDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQ 658
Query: 965 TEKKIIKLLLDHDPVRRPTASALLRSGWV 993
K +I+ LL DP +R S L + W+
Sbjct: 659 EAKDLIQGLLTVDPNKRLKMSGLRYNEWL 687
Score = 62.4 bits (150), Expect = 6e-09
Identities = 46/156 (29%), Positives = 83/156 (52%), Gaps = 18/156 (11%)
Query: 830 QILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGS 889
+I+ AL ++H GII+RD+K NI +D + ++ + DFGL+K ++ +T R SF
Sbjct: 160 EIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEF-VADETERAYSF----- 213
Query: 890 SGDLTSAIGTALYVASEIITSHGNYNEK-VDMYSLGIIFFEMI---YPFDTGMERVNVIK 945
GT Y+A +I+ + ++K VD +SLG++ +E++ PF E+ + +
Sbjct: 214 -------CGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAE 266
Query: 946 KLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRR 981
R I ++ + + K +I+ LL DP +R
Sbjct: 267 ISRRI-LKSEPPYPQEMSALAKDLIQRLLMKDPKKR 301
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 79.3 bits (194), Expect = 5e-14
Identities = 62/207 (29%), Positives = 104/207 (49%), Gaps = 30/207 (14%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S L++ MEY ++ + ++ + Q++ A+ Y+HS +IHRDLKP N+
Sbjct: 115 SYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYA-AQVVLAVQYLHSLDLIHRDLKPENL 173
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
ID+ +++ DFG AK V+ G + GT Y+A EII S G
Sbjct: 174 LIDQQGYLQVTDFGFAKRVK-----------------GRTWTLCGTPEYLAPEIILSKG- 215
Query: 914 YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE-KKII 970
YN+ VD ++LG++ +EM +P + + + +K+ + V FPS KL ++ K ++
Sbjct: 216 YNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPS-----KLSSDLKHLL 270
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKN 997
+ LL D +R LR+G +KN
Sbjct: 271 RSLLQVDLTKR---FGNLRNGVGDIKN 294
>ECU11g1290 [R] KOG0663 Protein kinase PITSLRE and related kinases
Length = 328
Score = 79.3 bits (194), Expect = 5e-14
Identities = 63/225 (28%), Positives = 99/225 (44%), Gaps = 48/225 (21%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
FI ME C+ L +IH+ K + L Q+L+ L ++H GI+HRDLKP NI +
Sbjct: 103 FIVMECCDT-DLRSVIHSVGKIGMKAARF-LTCQMLKGLKFLHGAGIVHRDLKPSNILLM 160
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
++I DFGLA+ ++ +T+ + T Y EI+ Y+E
Sbjct: 161 RDGGLRIADFGLARAIE-----------------SQMTNLVVTLWYRPIEILLGSETYDE 203
Query: 917 KVDMYSLGIIFFEMI-----------------------YPFDTGMERVNV-----IKKLR 948
+DM+S+G + EM+ YP D E +++ I++
Sbjct: 204 SIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADFEGLDLPHFKNIRRPS 263
Query: 949 NIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWV 993
+ F DF+ ++ LL DP +R TAS L SG+V
Sbjct: 264 TFEASFEGDFECYG-EEAASFVRNLLSFDPRKRCTASQGLCSGFV 307
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 490
Score = 79.3 bits (194), Expect = 5e-14
Identities = 61/222 (27%), Positives = 105/222 (46%), Gaps = 29/222 (13%)
Query: 800 MEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI---D 856
ME CE L+D I +++E +L + I+ + HS G++HRDLKP N D
Sbjct: 100 MELCEGGELFDRIVKRGHYSEREAA-KLIKTIVGVVEACHSLGVVHRDLKPENFLFSSSD 158
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
E ++K DFGL+ F + G + + +G+A YVA E++ H +Y
Sbjct: 159 EDASLKSTDFGLS-------------VFCTPGEA--FSELVGSAYYVAPEVL--HKHYGP 201
Query: 917 KVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLL 974
+ D++S G+I + ++ +P + + +K+ +EF + + K +IK +L
Sbjct: 202 ECDVWSAGVILYILLCGFPPFWAESEIGIFRKILQGKLEFEINPWPSISESAKDLIKKML 261
Query: 975 DHDPVRRPTASALLRSGWV------PVKNQDELIKEALKNIS 1010
+ +P +R TA +L W+ P K D + LK S
Sbjct: 262 ESNPKKRLTAHQVLCHPWIVDDKVAPDKPLDCAVVSRLKKFS 303
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand protein
superfamily
Length = 594
Score = 79.3 bits (194), Expect = 5e-14
Identities = 64/218 (29%), Positives = 105/218 (47%), Gaps = 34/218 (15%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+F+ ME CE L D I + E R+ QIL A ++ H QG++HRDLKP N F+
Sbjct: 219 VFVVMELCEGGELLDSILARGGRYPEAEAKRILVQILSATAFFHLQGVVHRDLKPEN-FL 277
Query: 856 DESRN----IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
S+N +K+ DFGL+ + Q L +G+A YVA E++ H
Sbjct: 278 FTSKNEDAVLKVIDFGLSDYARFDQ---------------RLNDVVGSAYYVAPEVL--H 320
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPF----DTGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
+Y+ + D++S+G+I + ++ PF ++ + R + D+ +PS
Sbjct: 321 RSYSTEADIWSIGVISYILLCGSRPFYGRTESAIFRCVLRANPNFDDLPWPSISP----- 375
Query: 965 TEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELI 1002
K +K LL+ D +R TA+ L W+ +N L+
Sbjct: 376 IAKDFVKRLLNKDHRKRMTAAQALAHPWLRDENPGLLL 413
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 79.3 bits (194), Expect = 5e-14
Identities = 59/204 (28%), Positives = 95/204 (45%), Gaps = 25/204 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ + + ME+ LYD + + + EE R+FRQ+ A+ Y H I HRDLK N
Sbjct: 152 REKMVLVMEFAAGGELYDYLSERKVLTE-EEARRIFRQVATAVYYCHKHKICHRDLKLEN 210
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
I +DE N KI DFGL+ NV Q L + G+ LY + EI+
Sbjct: 211 ILLDEKGNAKIADFGLS-NVFDDQRL--------------LGTFCGSPLYASPEIVEGTP 255
Query: 913 NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
+VD +SLG++ + ++Y PFD G ++K++ D ++ +K +
Sbjct: 256 YQGPEVDCWSLGVLLYTLVYGSMPFD-GSNFKRLVKQISQGDY-----YEPRKPSRASTL 309
Query: 970 IKLLLDHDPVRRPTASALLRSGWV 993
I+ +L P +R + + WV
Sbjct: 310 IRDMLTVCPRKRASIEQICSHWWV 333
>7298323 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 514
Score = 79.3 bits (194), Expect = 5e-14
Identities = 49/144 (34%), Positives = 71/144 (49%), Gaps = 14/144 (9%)
Query: 789 KSPRKSTLFIQMEYCENRTLYDLIHTE-SLNNQKEEYWRLFRQILEALSYIHSQGIIHRD 847
K + S +I +EY L+D I E + + E R F Q+L L+Y+H +GI HRD
Sbjct: 86 KRSQGSVEYIFLEYAAGGELFDRIGEEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRD 145
Query: 848 LKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
LKP N+ +DE N+KI DFG+A F G L GT YVA E+
Sbjct: 146 LKPENLLLDEHDNVKISDFGMA------------TMFRCKGKERLLDKRCGTLPYVAPEV 193
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMI 931
+ + + D++S G+I M+
Sbjct: 194 L-QKAYHAQPADLWSCGVILVTML 216
>At1g64630_2 [R] KOG0584 Serine/threonine protein kinase
Length = 495
Score = 79.3 bits (194), Expect = 5e-14
Identities = 77/238 (32%), Positives = 110/238 (45%), Gaps = 30/238 (12%)
Query: 829 RQILEALSYIHSQG--IIHRDLKPMNIFID-ESRNIKIGDFGLAKNVQISQDTLRRDSFT 885
RQIL+ L Y+HSQ +IHRDLK NIF++ + +KIGD GLA +Q Q T R
Sbjct: 95 RQILKGLHYLHSQTPPVIHRDLKCDNIFVNGNTGKVKIGDLGLAAVMQ--QPTAR----- 147
Query: 886 SAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVN 942
S IGT ++A E+ YNE VD+YS G+ EM+ YP+ +
Sbjct: 148 ---------SVIGTPEFMAPELYEEE--YNELVDIYSFGMCMLEMVTCEYPYRECRNQAQ 196
Query: 943 VIKKLRN-IDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKN-QDE 1000
+ KK+ + I + S DD ++ K+ I+ L P RPTA LL+ + V +D
Sbjct: 197 IYKKVTSGIKPQSLSKVDDPQV---KQFIEKCLLPAP-SRPTALELLKDQLLAVDGAKDS 252
Query: 1001 LIKEALKNISDPSSPWQQQVRENLFTQPYHLSSDILFDLSRSDTTPFLQLLRAQMVDE 1058
+ + P+ P Q + R + S I S LQ + Q V E
Sbjct: 253 TLTASSNTTFKPAMPPQCEYRPMDVEYKKNTSVSICSSAKSSQECALLQTMEVQRVAE 310
>Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 626
Score = 79.0 bits (193), Expect = 6e-14
Identities = 51/144 (35%), Positives = 75/144 (51%), Gaps = 23/144 (15%)
Query: 793 KSTLFIQMEYCENRTLYDLIH-----TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRD 847
+ TL I MEY ++ D + TES+ + RQILE +SY+HS I+HRD
Sbjct: 436 EKTLTIFMEYMPGGSVKDQLKAYGALTESVTR------KYTRQILEGMSYLHSNMIVHRD 489
Query: 848 LKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
+K NI D + N+K+GDFG +K +Q T S + S GT +++ E+
Sbjct: 490 IKGANILRDSAGNVKLGDFGASKRLQ-----------TICMSGTGMRSVTGTPYWMSPEV 538
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMI 931
I+ G Y K D++SLG EM+
Sbjct: 539 ISGEG-YGRKADVWSLGCTVVEML 561
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 79.0 bits (193), Expect = 6e-14
Identities = 74/264 (28%), Positives = 127/264 (48%), Gaps = 30/264 (11%)
Query: 746 VSKASASE--VTGLDSSKNDTLQEDGIGDMKFGRDKRSKMKSLSVKSPRKSTLFIQMEYC 803
V KA+ E V +D SK D +E I +++G+ + +L +++ E
Sbjct: 436 VHKATNMEYAVKVIDKSKRDPSEEIEIL-LRYGQ--HPNIITLKDVYDDGKHVYLVTELM 492
Query: 804 ENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI-FIDESRN-- 860
L D I + +++E + L I + + Y+HSQG++HRDLKP NI ++DES N
Sbjct: 493 RGGELLDKILRQKFFSEREASFVL-HTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPE 551
Query: 861 -IKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVD 919
++I DFG AK ++ +G L + TA +VA E++ G Y+E D
Sbjct: 552 CLRICDFGFAKQLR--------------AENGLLMTPCYTANFVAPEVLKRQG-YDEGCD 596
Query: 920 MYSLGIIFFEMI---YPFDTGMERV--NVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLL 974
++SLGI+ + M+ PF G ++ ++ + + T K ++ +L
Sbjct: 597 IWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKML 656
Query: 975 DHDPVRRPTASALLRSGWVPVKNQ 998
DP +R TA +L+ WV K++
Sbjct: 657 HVDPHQRLTAKQVLQHPWVTQKDK 680
Score = 66.2 bits (160), Expect = 4e-10
Identities = 51/190 (26%), Positives = 90/190 (46%), Gaps = 26/190 (13%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ +++ L+ + E + +++ + L L L ++HS GII+RDLKP NI +
Sbjct: 137 LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELAL-GLDHLHSLGIIYRDLKPENILL 195
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
DE +IK+ DFGL+K + S GT Y+A E++ G ++
Sbjct: 196 DEEGHIKLTDFGLSKE--------------AIDHEKKAYSFCGTVEYMAPEVVNRQG-HS 240
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE-KKIIK 971
D +S G++ FEM+ PF G +R + + + P + L TE + +++
Sbjct: 241 HSADWWSYGVLMFEMLTGSLPFQ-GKDRKETMTLILKAKLGMP-----QFLSTEAQSLLR 294
Query: 972 LLLDHDPVRR 981
L +P R
Sbjct: 295 ALFKRNPANR 304
>CE27573 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1420
Score = 79.0 bits (193), Expect = 6e-14
Identities = 71/233 (30%), Positives = 111/233 (47%), Gaps = 20/233 (8%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S + I MEYC TL + H + +Y +L A+ Y+HS IIHRD+KP NI
Sbjct: 1192 SDVIIFMEYCSQGTLERICHGKMDLKMVRQYTN---SLLRAVQYLHSHKIIHRDIKPANI 1248
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
F+D+ +K+GDFG + + + T+ + T+AG+ + I + E S+
Sbjct: 1249 FLDKCTVLKLGDFGCSSRL-VESSTVYGEFQTTAGTPQFMAPEI-YSYGEKDETTGSYSG 1306
Query: 914 YNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKL--RNIDVEFPSDFDDKKLHTEKK 968
Y VD+++LG M+ PF+ G R + L R +P D DK+ K+
Sbjct: 1307 YGRSVDIWALGATVVNMMTGKVPFE-GQTRHQIAFALCFRKQKPTYP-DIADKRPDV-KR 1363
Query: 969 IIKLLLDHDPVRRPTASALLRSGW--VPVKNQDE-----LIKEALKNISDPSS 1014
+ P RPTA+ LL++ + V + QDE ++ K+ S PSS
Sbjct: 1364 FFDNCFEFLPNDRPTAAELLQTTFANVNITFQDENHIPDYQSQSSKDKSSPSS 1416
>CE18366 [T] KOG0583 Serine/threonine protein kinase
Length = 331
Score = 79.0 bits (193), Expect = 6e-14
Identities = 62/207 (29%), Positives = 102/207 (48%), Gaps = 26/207 (12%)
Query: 801 EYCENRTLYDLIHTESLNNQKEEYWRL-FRQILEALSYIHSQGIIHRDLKPMNIFIDESR 859
E+C L L + + EE + FRQ + AL ++ S I+HRDLK NIF+D+
Sbjct: 116 EFCAGGDL--LRKMKKIKTMSEENAKFTFRQFIAALMHLQSYNIVHRDLKCENIFLDKYE 173
Query: 860 NIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVD 919
N+K+GDFG ++ ++ + SG + G+ YVA EI+ VD
Sbjct: 174 NVKLGDFGFSRILKPGE------------KSG---TFCGSRAYVAPEILRGREYSGNAVD 218
Query: 920 MYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDH 976
++S G+I + M+ PFD + +I++ ++F +H++ I+++L H
Sbjct: 219 VWSTGVILYIMLVGTMPFD-DRDPTRMIERQLAHKIKFGKTC-TASIHSKALILEILQPH 276
Query: 977 DPVRRPTASALLRSGWVPVKNQDELIK 1003
P RPT A+ S W +KNQ +K
Sbjct: 277 AP-NRPTYKAICESEW--LKNQPYYMK 300
>At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 599
Score = 79.0 bits (193), Expect = 6e-14
Identities = 59/206 (28%), Positives = 96/206 (45%), Gaps = 24/206 (11%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
+ ++I ME C L D I +++ + QIL +++ H QG++HRDLKP N
Sbjct: 219 ANVYIVMELCGGGELLDRILARGGKYSEDDAKAVLIQILNVVAFCHLQGVVHRDLKPENF 278
Query: 854 FI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
+E+ +K+ DFGL+ D +R D L +G+A YVA E++
Sbjct: 279 LYTSKEENSMLKVIDFGLS-------DFVRPDE--------RLNDIVGSAYYVAPEVL-- 321
Query: 911 HGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
H +Y + D++S+G+I + ++ PF E + + + D F K
Sbjct: 322 HRSYTTEADVWSIGVIAYILLCGSRPFWARTES-GIFRAVLKADPSFDEPPWPSLSFEAK 380
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
+K LL DP +R TAS L W+
Sbjct: 381 DFVKRLLYKDPRKRMTASQALMHPWI 406
>SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 496
Score = 78.6 bits (192), Expect = 8e-14
Identities = 59/202 (29%), Positives = 98/202 (48%), Gaps = 22/202 (10%)
Query: 797 FIQMEYCENRTLYDLIHTE-SLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
++ +E+ + L+D I + ++ +++ F Q++E +S++HS+G+ HRDLKP NI +
Sbjct: 88 WVVLEFAQGGDLFDKIEPDVGIDEDVAQFY--FAQLMEGISFMHSKGVAHRDLKPENILL 145
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D + N+KI DFG A F+ G S L S +G+ Y A EI +
Sbjct: 146 DYNGNLKISDFGFA------------SLFSYKGKSRLLNSPVGSPPYAAPEITQQYD--G 191
Query: 916 EKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHT-EKKIIK 971
KVD++S GII F ++ P+D + L E PS L II
Sbjct: 192 SKVDVWSCGIILFALLLGNTPWDEAISNTGDY-LLYKKQCERPSYHPWNLLSPGAYSIIT 250
Query: 972 LLLDHDPVRRPTASALLRSGWV 993
+L DP +R + +++ W+
Sbjct: 251 GMLRSDPFKRYSVKHVVQHPWL 272
>SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase
Length = 652
Score = 78.6 bits (192), Expect = 8e-14
Identities = 71/259 (27%), Positives = 115/259 (43%), Gaps = 27/259 (10%)
Query: 767 EDGIGDMKFGRDKRSKMKSLSVKSPRK--------STLFIQMEYCENRTLYDLIHTESLN 818
ED + D++ S++K V++ K + L+I M+YC ++ L+ ++
Sbjct: 47 EDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPIS 106
Query: 819 NQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDT 878
+ R+ L+AL +IH GIIHRD+K NI + S N+K+ DFG+A + I+
Sbjct: 107 EPCISL--ILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNIN--- 161
Query: 879 LRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMIYPFDTGM 938
RR T IGT ++A E+I YN D++SLGI +E I
Sbjct: 162 -RRKRIT----------FIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYE-IATGSPPH 209
Query: 939 ERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQ 998
+ + + + I P + K+ I L P RR +S LL+S + +K
Sbjct: 210 AKEDPFRAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDSSELLKSKF--IKQY 267
Query: 999 DELIKEALKNISDPSSPWQ 1017
+ L N+ WQ
Sbjct: 268 SRMSISELTNVVKRYDTWQ 286
>Hs4506091 [T] KOG0660 Mitogen-activated protein kinase
Length = 721
Score = 78.6 bits (192), Expect = 8e-14
Identities = 50/140 (35%), Positives = 74/140 (52%), Gaps = 17/140 (12%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMN 852
++++I EY E DL + EE+ RLF Q+L L YIHS ++HRDLKP N
Sbjct: 102 NSVYIVQEYMET----DLANVLEQGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPAN 157
Query: 853 IFID-ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+FI+ E +KIGDFGLA+ + G L+ + T Y + ++ S
Sbjct: 158 LFINTEDLVLKIGDFGLARIMD-----------PHYSHKGHLSEGLVTKWYRSPRLLLSP 206
Query: 912 GNYNEKVDMYSLGIIFFEMI 931
NY + +DM++ G IF EM+
Sbjct: 207 NNYTKAIDMWAAGCIFAEML 226
>Hs20986529 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 78.6 bits (192), Expect = 8e-14
Identities = 49/145 (33%), Positives = 76/145 (51%), Gaps = 15/145 (10%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
LY L+ T+ L+N Y+ QIL L YIHS ++HRDLKP N+ ++ + ++KI DFG
Sbjct: 112 LYKLLKTQHLSNDHICYF--LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG 169
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ D +G LT + T Y A EI+ + Y + +D++S+G I
Sbjct: 170 LARVADPDHD-----------HTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL 218
Query: 928 FEMI--YPFDTGMERVNVIKKLRNI 950
EM+ P G ++ +K + I
Sbjct: 219 AEMLSNRPIFPGKHYLDQLKHILGI 243
>At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 411
Score = 78.6 bits (192), Expect = 8e-14
Identities = 59/191 (30%), Positives = 87/191 (44%), Gaps = 26/191 (13%)
Query: 798 IQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
+ +EYC L LI T + +L + LSY+HSQ I+HRD+K N+ +D
Sbjct: 203 VVVEYCPGGALKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLD 262
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNE 916
+SR +KI DFG+A+ A + D+T GT Y+A E++ YN
Sbjct: 263 KSRTLKIADFGVAR--------------LEASNPNDMTGETGTLGYMAPEVLNG-SPYNR 307
Query: 917 KVDMYSLGIIFFE-----MIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
K D+YS GI +E M YP D V +N+ E P + ++K
Sbjct: 308 KCDVYSFGICLWEIYCCDMPYP-DLSFSEVTSAVVRQNLRPEIPRCCPSSLAN----VMK 362
Query: 972 LLLDHDPVRRP 982
D +P +RP
Sbjct: 363 RCWDANPEKRP 373
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 78.6 bits (192), Expect = 8e-14
Identities = 59/184 (32%), Positives = 96/184 (52%), Gaps = 24/184 (13%)
Query: 821 KEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLR 880
+E+ + +Q+++AL Y+HS IIHRD+KP NI I +K+ DFG A+ + + LR
Sbjct: 101 EEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTNTVVLR 160
Query: 881 RDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTG 937
S GT LY+A E++ Y+ VD++SLG+I +E+ PF T
Sbjct: 161 --------------SIKGTPLYMAPELVKEQ-PYDRTVDLWSLGVILYELYVGQPPFYTN 205
Query: 938 MERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKN 997
+V +R+I V+ P + D+ + +K LL+ +P R T AL +V +
Sbjct: 206 ----SVYALIRHI-VKDPVKYPDEMSTYFESFLKGLLNKEPHSRLTWPALREHPFVK-ET 259
Query: 998 QDEL 1001
Q+E+
Sbjct: 260 QEEV 263
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 78.2 bits (191), Expect = 1e-13
Identities = 61/213 (28%), Positives = 109/213 (50%), Gaps = 27/213 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
KS L++ +EY + L+D + ++ ++E F+QI+E +SY HS I HRDLKP N
Sbjct: 186 KSELYLVLEYVDGGELFDYLVSKGKLPEREAI-HYFKQIVEGVSYCHSFNICHRDLKPEN 244
Query: 853 IFID-ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
+ +D ++R IKI DFG+A +++ L+ TS GS Y + EI+
Sbjct: 245 LLLDKKNRRIKIADFGMAA-LELPNKLLK----TSCGSPH----------YASPEIVMGR 289
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
+ D++S GI+ F ++ PF+ + ++ K+++ + PS+ + +
Sbjct: 290 PYHGGPSDVWSCGIVLFALLTGHLPFNDDNIK-KLLLKVQSGKYQMPSNLSSE----ARD 344
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDEL 1001
+I +L DP +R T +L+ +K D+L
Sbjct: 345 LISKILVIDPEKRITTQEILKHPL--IKKYDDL 375
>YAR019c [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 974
Score = 78.2 bits (191), Expect = 1e-13
Identities = 74/265 (27%), Positives = 112/265 (41%), Gaps = 40/265 (15%)
Query: 792 RKS-TLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKP 850
RKS L+I +EYC N +L LI S + E Q L L Y+H +G+IHRD+K
Sbjct: 90 RKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKA 149
Query: 851 MNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
NI + +K+ DFG++ V S TL GT ++A EI+ +
Sbjct: 150 ANILLSADNTVKLADFGVSTIVNSSALTL-----------------AGTLNWMAPEILGN 192
Query: 911 HGNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
G + D++SLG EM+ P + N+ + N PS F + K
Sbjct: 193 RG-ASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPL----KD 247
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQP 1028
+ + +RPTA LL+ W+ N E +K N + +E+
Sbjct: 248 FLSKCFVKNMYKRPTADQLLKHVWI---NSTENVKVDKLN----------KFKEDFTDAD 294
Query: 1029 YHLSSDILFDLSRSDTTPFLQLLRA 1053
YH +D F + + +P LRA
Sbjct: 295 YHWDAD--FQEEKLNISPSKFSLRA 317
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 78.2 bits (191), Expect = 1e-13
Identities = 54/177 (30%), Positives = 90/177 (50%), Gaps = 24/177 (13%)
Query: 831 ILEALSYIHSQGIIHRDLKPMNI-FIDESR---NIKIGDFGLAKNVQISQDTLRRDSFTS 886
I + + Y+H QG++HRDLKP NI ++DES +I+I DFG AK ++
Sbjct: 527 ISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLR------------- 573
Query: 887 AGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERV-- 941
G +G L + TA +VA E++ G Y+ D++SLG++F+ M+ PF G
Sbjct: 574 -GENGLLLTPCYTANFVAPEVLMQQG-YDAACDIWSLGVLFYTMLAGYTPFANGPNDTPE 631
Query: 942 NVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQ 998
++ ++ N D K ++ +L DP +R TA +L+ W+ ++Q
Sbjct: 632 EILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQ 688
Score = 67.8 bits (164), Expect = 1e-10
Identities = 48/189 (25%), Positives = 89/189 (46%), Gaps = 24/189 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ +++ ++ + E L +++ + L L AL ++H GI++RDLKP NI +
Sbjct: 148 LYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELAL-ALDHLHQLGIVYRDLKPENILL 206
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
DE +IK+ DFGL+K S S GT Y+A E++ G ++
Sbjct: 207 DEIGHIKLTDFGLSKE--------------SVDQEKKAYSFCGTVEYMAPEVVNRRG-HS 251
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
+ D +S G++ FEM+ PF G +R + + + P + + ++++
Sbjct: 252 QSADWWSYGVLMFEMLTGTLPFQ-GKDRNETMNMILKAKLGMPQFLSAE----AQSLLRM 306
Query: 973 LLDHDPVRR 981
L +P R
Sbjct: 307 LFKRNPANR 315
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins
Length = 543
Score = 78.2 bits (191), Expect = 1e-13
Identities = 67/222 (30%), Positives = 104/222 (46%), Gaps = 30/222 (13%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRL-FRQILEALSYIHSQGIIHRDLKPMNIFI 855
+I +E E L+D + KE +L F Q+L A+ Y+H GIIHRDLKP N+ +
Sbjct: 298 YIVLELMEGGELFDKVVGNK--RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLL 355
Query: 856 ---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+E IKI DFG +K + G + + + GT Y+A E++ S G
Sbjct: 356 SSQEEDCLIKITDFGHSKIL---------------GETSLMRTLCGTPTYLAPEVLVSVG 400
Query: 913 --NYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
YN VD +SLG+I F + PF +V++ ++ + F + +
Sbjct: 401 TAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKAL 460
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNI 1009
++K LL DP R T LR W+ QDE +K +++
Sbjct: 461 DLVKKLLVVDPKARFTTEEALRHPWL----QDEDMKRKFQDL 498
>Hs20986531 [T] KOG0660 Mitogen-activated protein kinase
Length = 360
Score = 78.2 bits (191), Expect = 1e-13
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 13/124 (10%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
LY L+ T+ L+N Y+ QIL L YIHS ++HRDLKP N+ ++ + ++KI DFG
Sbjct: 112 LYKLLKTQHLSNDHICYF--LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFG 169
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ D +G LT + T Y A EI+ + Y + +D++S+G I
Sbjct: 170 LARVADPDHD-----------HTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL 218
Query: 928 FEMI 931
EM+
Sbjct: 219 AEML 222
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 78.2 bits (191), Expect = 1e-13
Identities = 50/146 (34%), Positives = 73/146 (49%), Gaps = 19/146 (13%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L++ +E+ L+D + + KE + FRQI+ AL + HS I HRDLKP N
Sbjct: 120 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEAR-KFFRQIVSALDFCHSYSICHRDLKPEN 178
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +DE NI+I DFG+A ++Q+ L TS GS Y E+I
Sbjct: 179 LLLDEKNNIRIADFGMA-SLQVGDSLLE----TSCGSPH----------YACPEVIKGEK 223
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFD 935
+ DM+S G+I F ++ PFD
Sbjct: 224 YDGRRADMWSCGVILFALLVGALPFD 249
>Hs19923464 [T] KOG0577 Serine/threonine protein kinase
Length = 898
Score = 78.2 bits (191), Expect = 1e-13
Identities = 89/366 (24%), Positives = 149/366 (40%), Gaps = 58/366 (15%)
Query: 792 RKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
++ T ++ MEYC + DL+ Q+ E + L L+Y+HS +IHRD+K
Sbjct: 93 KEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRDIKAG 151
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS- 910
NI + E +K+ DFG SA + S +GT ++A E+I +
Sbjct: 152 NILLTEPGQVKLADFG------------------SASMASPANSFVGTPYWMAPEVILAM 193
Query: 911 -HGNYNEKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNI-DVEFPSDFDDKKLHTEKK 968
G Y+ KVD++SLGI E+ + +N + L +I + P+ ++ + ++
Sbjct: 194 DEGQYDGKVDIWSLGITCIELA-ERKPPLFNMNAMSALYHIAQNDSPTLQSNEWTDSFRR 252
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQP 1028
+ L P RPT++ LLR +V ++ + ++ D VRE L
Sbjct: 253 FVDYCLQKIPQERPTSAELLRHDFVRRDRPLRVLIDLIQRTKD-------AVRE-LDNLQ 304
Query: 1029 YHLSSDILFDLSRSDTTPFLQLLRAQMVDEVIKIFRRHGAIENNEPPIIFPKAPI----- 1083
Y ILF +R+ L DE HG N E + I
Sbjct: 305 YRKMKKILFQETRNGP------LNESQEDEEDS---EHGTSLNREMDSLGSNHSIPSMSV 355
Query: 1084 ------YSTQNVYEVLDRGGSVLQLQYDLTYPMARYLSKNPNTTSKQYRMQYVFRPSEST 1137
S ++ EV+D S L + +D S +++S ++ +VF E+
Sbjct: 356 STGSQSSSVNSMQEVMDESSSELVMMHDDE-------STINSSSSVVHKKDHVFIRDEAG 408
Query: 1138 HSSTEP 1143
H P
Sbjct: 409 HGDPRP 414
>CE28674 [T] KOG0201 Serine/threonine protein kinase
Length = 651
Score = 78.2 bits (191), Expect = 1e-13
Identities = 58/221 (26%), Positives = 113/221 (50%), Gaps = 23/221 (10%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S L+I MEY + DL T+S + + R+IL+ L Y+HS+ IHRD+K N+
Sbjct: 101 SKLWIIMEYLGGGSALDL--TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANV 158
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+ E ++K+ DFG+A Q+++ +R +F +G+ ++A E+I +
Sbjct: 159 LVSEHGDVKVADFGVAG--QLTETVKKRITF------------VGSPFWMAPELI-KQSS 203
Query: 914 YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKL-RNIDVEFPSDFDDKKLHTEKKII 970
Y+ K D++SLGI E+ P + + + V+ + +N K K+ +
Sbjct: 204 YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPF---KEFV 260
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
++ L+ DP RP+AS LL+ ++ ++ ++ + ++ ++
Sbjct: 261 EMCLNKDPENRPSASTLLKHQFIKRAKKNSILVDLIERAAE 301
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 78.2 bits (191), Expect = 1e-13
Identities = 59/214 (27%), Positives = 102/214 (47%), Gaps = 26/214 (12%)
Query: 793 KSTLFIQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
++ +++ E CE L D L++ +SL ++KE + +L A+ Y+HSQ + HRDL
Sbjct: 518 ETAIYMIEELCEGGELLDKLVNKKSLGSEKEVA-AIMANLLNAVQYLHSQQVAHRDLTAA 576
Query: 852 NIFI----DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
NI + +++I DFG AK S +G L + TA +VA E+
Sbjct: 577 NILFALKDGDPSSLRIVDFGFAKQ--------------SRAENGMLMTPCYTAQFVAPEV 622
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERV--NVIKKLRNIDVEFPSDFDDKK 962
+ G Y+ D++SLG++ M+ PF G +++++ + + D
Sbjct: 623 LRKQG-YDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTI 681
Query: 963 LHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVK 996
K +++ +LD DP RR TA L+ W+ K
Sbjct: 682 SDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQK 715
Score = 68.2 bits (165), Expect = 1e-10
Identities = 47/163 (28%), Positives = 81/163 (48%), Gaps = 20/163 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ +++ L+ + E + + + + L L AL ++HS GI++RDLKP NI +
Sbjct: 179 LYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTL-ALEHLHSLGIVYRDLKPENILL 237
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D +IK+ DFGL+K + S S GT Y+A E+I G ++
Sbjct: 238 DADGHIKVTDFGLSKE--------------AIDSEKKTYSFCGTVEYMAPEVINRRG-HS 282
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFP 955
D +SLG++ FEM+ PF G +R + + ++ + P
Sbjct: 283 MAADFWSLGVLMFEMLTGHLPFQ-GRDRNDTMTQILKAKLSMP 324
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 78.2 bits (191), Expect = 1e-13
Identities = 59/214 (27%), Positives = 102/214 (47%), Gaps = 26/214 (12%)
Query: 793 KSTLFIQMEYCENRTLYD-LIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
++ +++ E CE L D L++ +SL ++KE + +L A+ Y+HSQ + HRDL
Sbjct: 461 ETAIYMIEELCEGGELLDKLVNKKSLGSEKEVA-AIMANLLNAVQYLHSQQVAHRDLTAA 519
Query: 852 NIFI----DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
NI + +++I DFG AK S +G L + TA +VA E+
Sbjct: 520 NILFALKDGDPSSLRIVDFGFAKQ--------------SRAENGMLMTPCYTAQFVAPEV 565
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERV--NVIKKLRNIDVEFPSDFDDKK 962
+ G Y+ D++SLG++ M+ PF G +++++ + + D
Sbjct: 566 LRKQG-YDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTI 624
Query: 963 LHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVK 996
K +++ +LD DP RR TA L+ W+ K
Sbjct: 625 SDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQK 658
Score = 68.2 bits (165), Expect = 1e-10
Identities = 47/163 (28%), Positives = 81/163 (48%), Gaps = 20/163 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L++ +++ L+ + E + + + + L L AL ++HS GI++RDLKP NI +
Sbjct: 122 LYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTL-ALEHLHSLGIVYRDLKPENILL 180
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D +IK+ DFGL+K + S S GT Y+A E+I G ++
Sbjct: 181 DADGHIKVTDFGLSKE--------------AIDSEKKTYSFCGTVEYMAPEVINRRG-HS 225
Query: 916 EKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFP 955
D +SLG++ FEM+ PF G +R + + ++ + P
Sbjct: 226 MAADFWSLGVLMFEMLTGHLPFQ-GRDRNDTMTQILKAKLSMP 267
>CE07510 [T] KOG0201 Serine/threonine protein kinase
Length = 653
Score = 78.2 bits (191), Expect = 1e-13
Identities = 58/221 (26%), Positives = 113/221 (50%), Gaps = 23/221 (10%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
S L+I MEY + DL T+S + + R+IL+ L Y+HS+ IHRD+K N+
Sbjct: 103 SKLWIIMEYLGGGSALDL--TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANV 160
Query: 854 FIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+ E ++K+ DFG+A Q+++ +R +F +G+ ++A E+I +
Sbjct: 161 LVSEHGDVKVADFGVAG--QLTETVKKRITF------------VGSPFWMAPELI-KQSS 205
Query: 914 YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKL-RNIDVEFPSDFDDKKLHTEKKII 970
Y+ K D++SLGI E+ P + + + V+ + +N K K+ +
Sbjct: 206 YDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPF---KEFV 262
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISD 1011
++ L+ DP RP+AS LL+ ++ ++ ++ + ++ ++
Sbjct: 263 EMCLNKDPENRPSASTLLKHQFIKRAKKNSILVDLIERAAE 303
>At4g24100 [T] KOG0582 Ste20-like serine/threonine protein kinase
Length = 710
Score = 78.2 bits (191), Expect = 1e-13
Identities = 52/174 (29%), Positives = 88/174 (49%), Gaps = 23/174 (13%)
Query: 827 LFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLR-RDSFT 885
+ ++ L+AL Y+H QG IHRD+K NI +D++ IK+GDFG++ + + D R R++F
Sbjct: 136 VLKETLKALDYLHRQGHIHRDVKAGNILLDDNGEIKLGDFGVSACLFDNGDRQRARNTF- 194
Query: 886 SAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVN 942
+GT ++A E++ YN K D++S GI E+ + PF
Sbjct: 195 -----------VGTPCWMAPEVLQPGNGYNSKADIWSFGITALELAHGHAPFSKYPPMKV 243
Query: 943 VIKKLRNIDVEFPSDFDDK-------KLHTEKKIIKLLLDHDPVRRPTASALLR 989
++ ++N D D K + K+++ + L D +RPTA LL+
Sbjct: 244 LLMTIQNAPPGLDYDRDKKFSKRTFSCAQSFKEMVAMCLVKDQTKRPTAEKLLK 297
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 78.2 bits (191), Expect = 1e-13
Identities = 63/211 (29%), Positives = 100/211 (46%), Gaps = 30/211 (14%)
Query: 792 RKSTLFIQMEYCENRTLYDLIHTES--LNNQKEEYWRLFRQILEALSYIHSQGIIHRDLK 849
+ +TL I+MEY + TL +I L+ + +F QI A++Y+HS+ I+HRDLK
Sbjct: 173 KDNTLLIEMEYADGGTLAQIIAERQGKLHFPERYIIAVFEQISSAINYMHSENILHRDLK 232
Query: 850 PMNIFIDESRNIKIGDFGLAK--NVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
N+F++ +KIGDFG++K N +I T+ +GT Y + E+
Sbjct: 233 TANVFLNRRGIVKIGDFGISKIMNTKIHAQTV-----------------LGTPYYFSPEM 275
Query: 908 ITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLH 964
Y+ K D+++LG I EM F V K + PS +
Sbjct: 276 CEGK-EYDNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGNYTPVPSGYTSGL-- 332
Query: 965 TEKKIIKLLLDHDPVRRPTASALLRSGWVPV 995
+ ++ LL + RRPTAS +L W+P+
Sbjct: 333 --RSLMSNLLQVEAPRRPTASEVL-VYWIPL 360
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 77.8 bits (190), Expect = 1e-13
Identities = 54/213 (25%), Positives = 102/213 (47%), Gaps = 26/213 (12%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+++ +E+ LY + +++ +F Q+ ALSY+H + +IHRD+KP NI +
Sbjct: 191 IYLILEFAGRGELYQHLRRAKRFSEEVASKYIF-QMANALSYLHKKHVIHRDIKPENILL 249
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
IK+ DFG ++ S T+ GT Y+ E++ +
Sbjct: 250 GIDGEIKLSDFG----------------WSVHAPSNRRTTLCGTLDYLPPEMVEGK-EHT 292
Query: 916 EKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKL 972
EKVD++SLG++ +E + PF+ K++ +D++ PS + +I
Sbjct: 293 EKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPP----DARDLISR 348
Query: 973 LLDHDPVRRPTASALLRSGWVPVKNQDELIKEA 1005
LL H+P +R + ++R W+ VK +D +++
Sbjct: 349 LLQHNPEKRMSLEQVMRHPWI-VKYKDSWTRKS 380
>SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase
Length = 312
Score = 77.8 bits (190), Expect = 1e-13
Identities = 45/135 (33%), Positives = 75/135 (55%), Gaps = 16/135 (11%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L+I MEYC+ + DL+ +++ + RQ+LEAL Y+H QG +HRD+K NI
Sbjct: 77 LWITMEYCDGGSCLDLLKLSGTFSERV-IAEVMRQVLEALVYLHGQGKMHRDIKAANILT 135
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+ +K+ DFG++ ++ +D + D F +GT ++A E++ G YN
Sbjct: 136 MKDGLVKLADFGVSGQLESLRD--KNDDF------------VGTPFWMAPEVVKQTG-YN 180
Query: 916 EKVDMYSLGIIFFEM 930
K D++SLGI +E+
Sbjct: 181 YKADIWSLGITAYEL 195
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 77.8 bits (190), Expect = 1e-13
Identities = 54/202 (26%), Positives = 98/202 (47%), Gaps = 28/202 (13%)
Query: 796 LFIQMEYCENRTLY-DLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
+++ +EY T+Y +L + Q+ + ++ ALSY HS+ +IHRD+KP N+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATY--ITELANALSYCHSKRVIHRDIKPENLL 263
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNY 914
+ + +KI DFG + + S+ T+ GT Y+ E+I +
Sbjct: 264 LGSAGELKIADFGWSVHAPSSR----------------RTTLCGTLDYLPPEMIEGR-MH 306
Query: 915 NEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
+EKVD++SLG++ +E + PF+ + K++ ++ FP D + +I
Sbjct: 307 DEKVDLWSLGVLCYEFLVGKPPFEANTYQ-ETYKRISRVEFTFP----DFVTEGARDLIS 361
Query: 972 LLLDHDPVRRPTASALLRSGWV 993
LL H+P +RP +L W+
Sbjct: 362 RLLKHNPSQRPMLREVLEHPWI 383
>Hs20562757 [T] KOG0660 Mitogen-activated protein kinase
Length = 379
Score = 77.8 bits (190), Expect = 1e-13
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 13/124 (10%)
Query: 808 LYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFG 867
LY L+ ++ L+N Y+ QIL L YIHS ++HRDLKP N+ I+ + ++KI DFG
Sbjct: 129 LYKLLKSQQLSNDHICYF--LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFG 186
Query: 868 LAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
LA+ D +G LT + T Y A EI+ + Y + +D++S+G I
Sbjct: 187 LARIADPEHD-----------HTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL 235
Query: 928 FEMI 931
EM+
Sbjct: 236 AEML 239
>CE29020 [T] KOG0660 Mitogen-activated protein kinase
Length = 470
Score = 77.8 bits (190), Expect = 1e-13
Identities = 45/156 (28%), Positives = 82/156 (51%), Gaps = 10/156 (6%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
+++ E+ E L+++I S+ + + + Q+ A+ ++HS ++HRDLKP N+ +
Sbjct: 88 IYLAFEFME-ADLHNVIKKGSILKDVHKQY-IMCQLFRAIRFLHSGNVLHRDLKPSNVLL 145
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D +K+ DFGLA+++ +D + DLT + T Y + EI+ + Y
Sbjct: 146 DADCRVKLADFGLARSLSSLED------YPEGQKMPDLTEYVATRWYRSPEILLAAKRYT 199
Query: 916 EKVDMYSLGIIFFEMIY--PFDTGMERVNVIKKLRN 949
+ VDM+SLG I EM+ G +N I+++ N
Sbjct: 200 KGVDMWSLGCILAEMLIGRALFPGSSTINQIERIMN 235
>CE09940 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 468
Score = 77.8 bits (190), Expect = 1e-13
Identities = 61/226 (26%), Positives = 109/226 (47%), Gaps = 28/226 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L IQ+E C+ ++L H KE W +F IL+ L ++H+ ++H D+KP N
Sbjct: 172 KQILHIQLEMCD-KSLAAYCHGIDWLEDKE-LWNVFLDILQGLGHLHNNFMLHNDIKPDN 229
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
IF+ +++ K+GDFGL +++ + + S S GD Y + E I +G
Sbjct: 230 IFMTKNKVCKLGDFGLISDMR--SEPINNSSNKHYQSEGD-------GKYCSKEAI--NG 278
Query: 913 NYNEKVDMYSLGIIFFEM-----IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
+ D++S GI E+ + + TG E + E P + + +
Sbjct: 279 TLSIFSDIFSFGISILEVGTNIHLPSYGTGWEPIR--------KWEIPEEILEPMSDELR 330
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPS 1013
+++K ++D P RRPT S L+++ VK + + K+ +++I S
Sbjct: 331 ELVKQMMDKAPTRRPTCSELMKNH--VVKEKLRIRKQEVEHIPSES 374
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 77.8 bits (190), Expect = 1e-13
Identities = 63/210 (30%), Positives = 101/210 (48%), Gaps = 26/210 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPM 851
+ L++ MEY LY L+ +L +E+ R++ +++ AL Y+HS+G++HRDLKP
Sbjct: 960 RDNLYLVMEYLNGGDLYSLLR--NLGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDLKPD 1017
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQ------------DTLRRDSFTSAGSSGDL-----T 894
N+ I +IK+ DFGL+K I+ L + A S L
Sbjct: 1018 NLLIAHDGHIKLTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERRKKR 1077
Query: 895 SAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNID 951
SA+GT Y+A EI+ G + D +S+GII FE+I PF+ + + + N
Sbjct: 1078 SAVGTPDYLAPEILLGTG-HGATADWWSVGIILFELIVGIPPFNAEHPQ-QIFDNILNRK 1135
Query: 952 VEFPSDFDDKKLHTEKKIIKLLLDHDPVRR 981
+ +P ++ II L DP +R
Sbjct: 1136 IPWPHVPEEMSAEAH-DIIDRFLTEDPHQR 1164
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 77.8 bits (190), Expect = 1e-13
Identities = 64/242 (26%), Positives = 113/242 (46%), Gaps = 32/242 (13%)
Query: 765 LQEDGIGDMKFGRDKRSKMKSLSV-KSPR----------KSTLFIQMEYCENRTLYDLIH 813
+ + I D+ F + ++++L + K P K+ + + ME L+D I
Sbjct: 51 IDKSRIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIV 110
Query: 814 TESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQ 873
+ + + ++F+Q+++ +SY HS+G+ HRDLK N+ +D +IKI DFGL+ Q
Sbjct: 111 SNGKLTETDGR-KMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQ 169
Query: 874 ISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI-- 931
+D G L + G+ YVA E++ + G D++S G+I + ++
Sbjct: 170 HFRD------------DGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTG 217
Query: 932 -YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRS 990
PFD V + +K+ D P + +IK +LD +PV R T + S
Sbjct: 218 CLPFDDRNLAV-LYQKICKGDPPIPRWLSP----GARTMIKRMLDPNPVTRITVVGIKAS 272
Query: 991 GW 992
W
Sbjct: 273 EW 274
>CE14884_1 [D] KOG0601 Cyclin-dependent kinase WEE1
Length = 415
Score = 77.8 bits (190), Expect = 1e-13
Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 21/193 (10%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFI 855
L+IQ E C+ L +L ++E W +F +L+A+ ++HS +IH D+KP NIF+
Sbjct: 179 LYIQTELCDQSLLKYCTEKHAL--PEDEIWNIFVDLLQAVHHLHSNDMIHDDIKPENIFL 236
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
+ K+GDFGL N++ D + G + Y+A E++ +G
Sbjct: 237 TKDMICKLGDFGLVINLKNPNDVKSAEE--------------GDSKYLAPEVL--NGRPT 280
Query: 916 EKVDMYSLGIIFFEMIYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLD 975
+ D++SLG+ E D + ++RN + P F + +I L+LD
Sbjct: 281 KSSDIFSLGMTILEATTDLDV-PSNGDSWHQIRN--GQIPDRFFAGISTDLRSLIALMLD 337
Query: 976 HDPVRRPTASALL 988
DP RPT+ LL
Sbjct: 338 SDPRIRPTSRDLL 350
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 77.4 bits (189), Expect = 2e-13
Identities = 64/244 (26%), Positives = 112/244 (45%), Gaps = 39/244 (15%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEY---WRLFRQILEALSYIHSQGIIHRDLKPMN 852
L+I MEYC+ L I + E+ W F Q+ +++IH + ++HRD+K N
Sbjct: 75 LYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNW--FTQMCLGVNHIHKKRVLHRDIKSKN 132
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
IF+ ++ +K+GDFG A+ + + + +GT YV E I +
Sbjct: 133 IFLTQNGKVKLGDFGSARLL--------------SNPMAFACTYVGTPYYVPPE-IWENL 177
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
YN K D++SLG I +E+ +PF + ++K + PS + + + +
Sbjct: 178 PYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYS----YELQFL 233
Query: 970 IKLLLDHDPVRRPTASALLRSGWVP-----------VKNQDELIKEALKNISDPSSPWQQ 1018
+K + +P RP+A+ LL G V + E + E +KN S ++P ++
Sbjct: 234 VKQMFKRNPSHRPSATTLLSRGIVARLVQKCLPPEIIMEYGEEVLEEIKN-SKHNTPRKK 292
Query: 1019 QVRE 1022
Q E
Sbjct: 293 QEEE 296
>At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound)
p21cdc42Hs
Length = 736
Score = 77.4 bits (189), Expect = 2e-13
Identities = 57/203 (28%), Positives = 100/203 (49%), Gaps = 37/203 (18%)
Query: 798 IQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQG--IIHRDLKPMNIFI 855
I MEY +L+ ++H + K+ R+ + ++Y+H + I+HRDLK N+ +
Sbjct: 540 IIMEYMPRGSLFKILHNTNQPLDKKRRLRMALDVARGMNYLHRRNPPIVHRDLKSSNLLV 599
Query: 856 DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYN 915
D++ N+K+GDFGL+K + +F S S GT ++A E++ S + N
Sbjct: 600 DKNWNVKVGDFGLSK--------WKNATFLST------KSGKGTPQWMAPEVLRSEPS-N 644
Query: 916 EKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK----- 967
EK D++S G+I +E+ + P+D +L +I V F D++L +
Sbjct: 645 EKCDVFSFGVILWELMTTLVPWD----------RLNSIQVVGVVGFMDRRLDLPEGLNPR 694
Query: 968 --KIIKLLLDHDPVRRPTASALL 988
II+ DP +RP+ L+
Sbjct: 695 IASIIQDCWQTDPAKRPSFEELI 717
>At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 595
Score = 77.4 bits (189), Expect = 2e-13
Identities = 61/210 (29%), Positives = 104/210 (49%), Gaps = 32/210 (15%)
Query: 794 STLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNI 853
+ ++I ME C+ L D I +++ + QIL +S+ H QG++HRDLKP N
Sbjct: 218 NNVYIVMELCDGGELLDRILARGGKYPEDDAKAIVVQILTVVSFCHLQGVVHRDLKPENF 277
Query: 854 FIDESR---NIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITS 910
SR ++K+ DFGL+ D +R D L +G+A YVA E++
Sbjct: 278 LFTSSREDSDLKLIDFGLS-------DFIRPDE--------RLNDIVGSAYYVAPEVL-- 320
Query: 911 HGNYNEKVDMYSLGIIFFEMI---YPF----DTGMERVNVIKKLRNIDVEFPSDFDDKKL 963
H +Y+ + D++S+G+I + ++ PF ++G+ R + + DV +PS +
Sbjct: 321 HRSYSLEADIWSIGVITYILLCGSRPFWARTESGIFRTVLRTEPNYDDVPWPSCSSE--- 377
Query: 964 HTEKKIIKLLLDHDPVRRPTASALLRSGWV 993
K +K LL+ D +R +A L W+
Sbjct: 378 --GKDFVKRLLNKDYRKRMSAVQALTHPWL 405
>At1g09600 [D] KOG0600 Cdc2-related protein kinase
Length = 714
Score = 77.4 bits (189), Expect = 2e-13
Identities = 50/165 (30%), Positives = 82/165 (49%), Gaps = 19/165 (11%)
Query: 788 VKSPRKSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRD 847
+ S ++++ EY E+ L L T +N + + +Q+L L + HS+G++HRD
Sbjct: 229 ITSRVSGSMYLIFEYMEH-DLAGLASTPGINFSEAQIKCYMKQLLHGLEHCHSRGVLHRD 287
Query: 848 LKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEI 907
+K N+ +D + N+KIGDFGLA +F LTS + T Y E+
Sbjct: 288 IKGSNLLLDHNNNLKIGDFGLA-------------NFYQGHQKQPLTSRVVTLWYRPPEL 334
Query: 908 ITSHGNYNEKVDMYSLGIIFFEM-----IYPFDTGMERVNVIKKL 947
+ +Y VD++S G I E+ I P T +E+++ I KL
Sbjct: 335 LLGSTDYGVTVDLWSTGCILAELFTGKPIMPGRTEVEQLHKIFKL 379
>7300435 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1612
Score = 77.4 bits (189), Expect = 2e-13
Identities = 69/231 (29%), Positives = 97/231 (41%), Gaps = 42/231 (18%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPM 851
+ L I ME C TL L+ E N E R F Q+L +S +H GI+HRD+K
Sbjct: 1392 REELLIFMELCSEGTLESLV--ELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTA 1449
Query: 852 NIF-IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEII-- 908
NIF +D S ++K+GDFG A +Q G+L +GT Y+A E+
Sbjct: 1450 NIFLVDGSNSLKLGDFGSAVKIQAHTTV-----------PGELQGYVGTQAYMAPEVFTK 1498
Query: 909 TSHGNYNEKVDMYSLGIIFFEMI------YPFDTGMERVNVIKKLRNIDVEFPSDFDDKK 962
T+ + D++S+G + EM FD+ N + F +K
Sbjct: 1499 TNSDGHGRAADIWSVGCVVVEMASGKRPWAQFDS------------NFQIMFKVGMGEKP 1546
Query: 963 LHTEK------KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALK 1007
E I L HDP RR TA LL + +DE E L+
Sbjct: 1547 QAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKY-GRDECSSEQLQ 1596
>7290313 [T] KOG0193 Serine/threonine protein kinase RAF
Length = 739
Score = 77.4 bits (189), Expect = 2e-13
Identities = 43/141 (30%), Positives = 72/141 (50%), Gaps = 14/141 (9%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K +L I ++CE +LY +H + + RQ+ + + Y+H++ IIHRDLK N
Sbjct: 494 KPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNN 553
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH- 911
IF+ E ++KIGDFGLA + T G+ L++A E+I
Sbjct: 554 IFLHEDLSVKIGDFGLA------------TAKTRWSGEKQANQPTGSILWMAPEVIRMQE 601
Query: 912 -GNYNEKVDMYSLGIIFFEMI 931
Y+ + D+Y+ GI+ +E++
Sbjct: 602 LNPYSFQSDVYAFGIVMYELL 622
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 77.4 bits (189), Expect = 2e-13
Identities = 62/219 (28%), Positives = 103/219 (46%), Gaps = 31/219 (14%)
Query: 796 LFIQMEYCENRTLYDLIHTES----LNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
L+I M +CE LY + + NQ E+ F QI AL Y+H + I+HRDLK
Sbjct: 79 LYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEW---FVQIAMALQYLHEKHILHRDLKTQ 135
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
N+F+ + IK+GD G+A+ ++ D ++ IGT Y++ E+ S+
Sbjct: 136 NVFLTRTNIIKVGDLGIARVLENHCDM--------------ASTLIGTPYYMSPELF-SN 180
Query: 912 GNYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKK 968
YN K D+++LG +EM + F+ V + + P D+ + +
Sbjct: 181 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPAMPRDYSPEL----AE 236
Query: 969 IIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALK 1007
+I+ +L P RP+ ++LR + +K Q EA K
Sbjct: 237 LIRTMLSKRPEERPSVRSILRQPY--IKRQISFFLEATK 273
>YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 939
Score = 77.0 bits (188), Expect = 2e-13
Identities = 59/206 (28%), Positives = 103/206 (49%), Gaps = 26/206 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K L++ MEY E +L D++ L + + + R+ L L ++HS+G++HRD+K N
Sbjct: 687 KGDLWVIMEYMEGGSLTDVVTHCILT--EGQIGAVCRETLSGLEFLHSKGVLHRDIKSDN 744
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
I + +IK+ DFG QI++ L+R T+ +GT ++A E++ S
Sbjct: 745 ILLSMEGDIKLTDFGFC--AQINELNLKR------------TTMVGTPYWMAPEVV-SRK 789
Query: 913 NYNEKVDMYSLGIIFFEMI-----YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
Y KVD++SLGI+ EMI Y +T + + +I ++ P + + K
Sbjct: 790 EYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSS----SLK 845
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWV 993
K + L +P R +A+ LL ++
Sbjct: 846 KFLDWCLCVEPEDRASATELLHDEYI 871
>SPCC1919.01 [T] KOG0583 Serine/threonine protein kinase
Length = 203
Score = 77.0 bits (188), Expect = 2e-13
Identities = 64/227 (28%), Positives = 112/227 (49%), Gaps = 34/227 (14%)
Query: 800 MEYCENRTLYDLIHTESLNNQKEEYWRL-FRQILEALSYIHSQGIIHRDLKPMNIFIDES 858
+ YC L + H S + E R FRQ++ A++YIH +G+IHRD+KP NI E+
Sbjct: 1 LNYCPGGKLASVDHGISFDPMPLETCRKSFRQLVLAVNYIHGKGVIHRDIKPDNILFKEN 60
Query: 859 RNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN--YNE 916
N+ + DFGLA + L +D F S GT ++A E+ + +
Sbjct: 61 NNLCVIDFGLA-------EFLPKDGFVKPAS--------GTPAFMAPELFDNELKKIKGK 105
Query: 917 KVDMYSLGIIFFEMI---YPFD--TGMERVNVIK-KLRNIDVEFPSDFDDKKLHTEKKII 970
+D++S+G+ + + +PF+ T ++ +NVIK K I SD +K++
Sbjct: 106 PLDIWSMGVTLYVIAFAEFPFNGSTILDMINVIKGKSLMIPAYCNSDL--------RKLL 157
Query: 971 KLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQ 1017
+ L+ +P +R T LLR ++ + + L ++ ++ SS W+
Sbjct: 158 ERCLEKNPEKRITIEELLRDPFLTERGKHHLTSSSI--VTAFSSIWE 202
>SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase
Length = 471
Score = 77.0 bits (188), Expect = 2e-13
Identities = 62/202 (30%), Positives = 98/202 (47%), Gaps = 23/202 (11%)
Query: 795 TLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIF 854
TL+I ME+ + ++ L+ LN Q + R++L L+Y+H Q IHRD+K NI
Sbjct: 79 TLWILMEHMDGGSVSGLLKMGRLNEQVISI--ILREVLYGLNYLHGQNKIHRDIKAANIL 136
Query: 855 IDESR-NIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGN 913
+ S N+K+ DFG+A Q+S RR +F +GT ++A E+I +
Sbjct: 137 LSSSTGNVKLADFGVA--AQLSNAASRRHTF------------VGTPFWMAPEVI-QQTS 181
Query: 914 YNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIK 971
Y D++SLGI EM P M + VI ++ + P DD T + +
Sbjct: 182 YGLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSE---PPKLDDHFSPTFRDFVS 238
Query: 972 LLLDHDPVRRPTASALLRSGWV 993
LD +P R +A LL+ ++
Sbjct: 239 CCLDLNPNMRWSAKELLQHPFI 260
>Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 387
Score = 77.0 bits (188), Expect = 2e-13
Identities = 54/199 (27%), Positives = 96/199 (48%), Gaps = 23/199 (11%)
Query: 797 FIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFID 856
F+ + + L+D + TE + ++E ++ R +LE + +H I+HRDLKP NI +D
Sbjct: 101 FLVFDLMKRGELFDYL-TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLD 159
Query: 857 ESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEII-----TSH 911
++ NIK+ DFG + ++ + L GT Y+A EII H
Sbjct: 160 DNMNIKLTDFGFSCQLEPGE---------------RLREVCGTPSYLAPEIIECSMNEDH 204
Query: 912 GNYNEKVDMYSLGIIFFEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
Y ++VDM+S G+I + ++ P +++ +++ + + + +F S D T K +
Sbjct: 205 PGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDL 264
Query: 970 IKLLLDHDPVRRPTASALL 988
+ L P R TA L
Sbjct: 265 VSRFLVVQPQNRYTAEEAL 283
>At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 554
Score = 77.0 bits (188), Expect = 2e-13
Identities = 56/207 (27%), Positives = 103/207 (49%), Gaps = 25/207 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
+ ++ + ME C L+D I + ++K + R +L + H G+IHRDLKP N
Sbjct: 173 RQSIHLVMELCGGSELFDRIIAQGHYSEKAAAG-VIRSVLNVVQICHFMGVIHRDLKPEN 231
Query: 853 IFI---DESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIIT 909
+ DE+ +K DFGL +V I + + RD +G+A YVA E++
Sbjct: 232 FLLASTDENAMLKATDFGL--SVFIEEGKVYRD-------------IVGSAYYVAPEVL- 275
Query: 910 SHGNYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTE 966
+Y +++D++S GII + + + PF + E+ + ++ +++F S +
Sbjct: 276 -RRSYGKEIDIWSAGIILYILLCGVPPFWSETEK-GIFNEIIKGEIDFDSQPWPSISESA 333
Query: 967 KKIIKLLLDHDPVRRPTASALLRSGWV 993
K +++ LL DP +R +A+ L W+
Sbjct: 334 KDLVRKLLTKDPKQRISAAQALEHPWI 360
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 77.0 bits (188), Expect = 2e-13
Identities = 59/201 (29%), Positives = 99/201 (48%), Gaps = 20/201 (9%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPMNIF 854
L++ MEY Y ++ + E R++ +++ AL Y+HS+G++HRDLKP N+
Sbjct: 901 LYLVMEYLNGGDFYSMLR--KIGCLDEANARVYIAEVVLALEYLHSEGVVHRDLKPDNLL 958
Query: 855 IDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGS-----------SGDLTSAIGTALYV 903
I ++K+ DFGL+K I+ +SA S SA+GT Y+
Sbjct: 959 IAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATSLLVEEKPKLPTLDHKRSAVGTPDYL 1018
Query: 904 ASEIITSHGNYNEKVDMYSLGIIFFEM---IYPFDTGMERVNVIKKLRNIDVEFPSDFDD 960
A EI+ G + D +S+GII +E I PF+ + + + N ++++P +D
Sbjct: 1019 APEILLGTG-HGATADWWSVGIILYEFLVGIPPFNADHPQ-QIFDNILNRNIQWPPVPED 1076
Query: 961 KKLHTEKKIIKLLLDHDPVRR 981
H + +I LL DP +R
Sbjct: 1077 MS-HEARDLIDRLLTEDPHQR 1096
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 77.0 bits (188), Expect = 2e-13
Identities = 55/203 (27%), Positives = 101/203 (49%), Gaps = 21/203 (10%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPMN 852
K+ +++ +E L+D I ++ ++ + ++F+Q+++ +SY H++G+ HRDLK N
Sbjct: 81 KTKIYMVLECVTGGDLFDRIVSKGKLSETQGR-KMFQQLIDGVSYCHNKGVFHRDLKLEN 139
Query: 853 IFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHG 912
+ +D +IKI DFGL+ Q ++ G L + G+ YVA E++ + G
Sbjct: 140 VLLDAKGHIKITDFGLSALSQHYRE------------DGLLHTTCGSPNYVAPEVLANEG 187
Query: 913 NYNEKVDMYSLGIIFFEMI---YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKI 969
D++S G+I + ++ PFD V + +K+ D P K +
Sbjct: 188 YDGAASDIWSCGVILYVILTGCLPFDDANLAV-ICRKIFKGDPPIPRWIS----LGAKTM 242
Query: 970 IKLLLDHDPVRRPTASALLRSGW 992
IK +LD +PV R T + + W
Sbjct: 243 IKRMLDPNPVTRVTIAGIKAHDW 265
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 76.6 bits (187), Expect = 3e-13
Identities = 72/261 (27%), Positives = 121/261 (45%), Gaps = 33/261 (12%)
Query: 793 KSTLFIQMEYCENRTLYDLIHTE-SLNNQKEEYWRLFRQILEALSYIHSQGIIHRDLKPM 851
+++L+ +EY + LI SLN Y+ QI++A+ +H+ GIIHRD+KP
Sbjct: 196 EASLYFLLEYAPHGDFLGLIKKYGSLNETCARYYA--SQIIDAVDSLHNIGIIHRDIKPE 253
Query: 852 NIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSH 911
NI +D++ +K+ DFG AK + + + D S +GTA YV+ E++ +
Sbjct: 254 NILLDKNMKVKLTDFGTAK-ILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELL--N 310
Query: 912 GNYNE-KVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEK 967
NY + + D+++ G I ++M+ PF E + +K+ I F + F K
Sbjct: 311 DNYTDSRCDIWAFGCILYQMLAGKPPFKAANEYL-TFQKVMKIQYAFTAGFP----QIVK 365
Query: 968 KIIKLLLDHDPVRRPTASALLRSGWVPVKNQDELIKEALKNISDPSSPWQQQVRENLFTQ 1027
++K LL DP R T + + N ++ S W E Q
Sbjct: 366 DLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFED------------GSVWDDNPPE---IQ 410
Query: 1028 PYHLSSDILFDL---SRSDTT 1045
PY ++++ + L S SDTT
Sbjct: 411 PYKINAEAMKPLQKVSESDTT 431
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 76.6 bits (187), Expect = 3e-13
Identities = 63/205 (30%), Positives = 98/205 (47%), Gaps = 22/205 (10%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMNIF 854
L++ MEYC + +H+ + E+ + ++ AL Y+H G I+RDLKP NI
Sbjct: 228 LYLCMEYCAGGEFFRALHSLPKHILPEKDACFYAAEVTAALEYLHLMGFIYRDLKPENIL 287
Query: 855 IDESRNIKIGDFGLAKNVQI--------------SQDTLRRDSFTSAGSSGDLTSAIGTA 900
+ +S +I + DF L+K + I SQ+ D+ S S+ S +GT
Sbjct: 288 LHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDT-NSYFSNFRTNSFVGTE 346
Query: 901 LYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSD 957
Y+A E+I S G + VD ++LGI +E++Y PF G R + DV FP
Sbjct: 347 EYIAPEVIRSCG-HTVAVDWWTLGIFIYEILYGTTPF-KGKNRHATFSNILYSDVSFPEY 404
Query: 958 FDDKKL-HTEKKIIKLLLDHDPVRR 981
+ T K +I+ LL D +R
Sbjct: 405 HGAPNVSSTCKSLIRRLLVKDESKR 429
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 76.6 bits (187), Expect = 3e-13
Identities = 61/201 (30%), Positives = 94/201 (46%), Gaps = 22/201 (10%)
Query: 796 LFIQMEYCENRTLYDLIHTESLNNQKEEYWRLF-RQILEALSYIHSQGIIHRDLKPMNIF 854
L++ MEYC + + E + + ++ AL Y+H G I+RDLKP NI
Sbjct: 268 LYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHLMGFIYRDLKPENIL 327
Query: 855 IDESRNIKIGDFGL--------------AKNVQISQDTLRRDSFTSAGSSGDLTSAIGTA 900
+ ES +I + DF L A+N +Q+ D+ S + S +GT
Sbjct: 328 LHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAYALDT-KSCIADFRTNSFVGTE 386
Query: 901 LYVASEIITSHGNYNEKVDMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSD 957
Y+A E+I G + VD ++LGI+F+EM+Y PF G R + + DV FP
Sbjct: 387 EYIAPEVIKGCG-HTSAVDWWTLGILFYEMLYATTPF-KGKNRNMTFSNILHKDVIFPEY 444
Query: 958 FDDKKLHTE-KKIIKLLLDHD 977
D + + K +I+ LL D
Sbjct: 445 ADAPSISSLCKNLIRKLLVKD 465
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 76.6 bits (187), Expect = 3e-13
Identities = 67/218 (30%), Positives = 104/218 (46%), Gaps = 44/218 (20%)
Query: 798 IQMEYCENRTLYDLIHT---ESLNNQKEEYWRLFRQILEALSYIH--------------- 839
+ MEYC + L +LI E ++E + F Q+L AL H
Sbjct: 80 LYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHYGENAPACDSQWPRE 139
Query: 840 ----SQGIIHRDLKPMNIFIDESRNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTS 895
Q ++HRD+KP NIF+DE+ ++K+GDFGL+K + ++ FT S
Sbjct: 140 IFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTR------VFTQ--------S 185
Query: 896 AIGTALYVASEIITSHGNYNEKVDMYSLGIIFFE---MIYPFDTGMERVNVIKKLRNIDV 952
+GT Y++ EII S Y+ K D+++LG + FE + +PF E + ++ RNI
Sbjct: 186 YVGTPYYMSPEIIRS-SPYSAKSDVWALGCVIFEICMLTHPF----EGRSYLELQRNICQ 240
Query: 953 EFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRS 990
S +D +I+ L+ + RPT LLRS
Sbjct: 241 GNLSCWDHHYSDDVFLLIRHCLEVNSDLRPTTYQLLRS 278
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 76.6 bits (187), Expect = 3e-13
Identities = 55/198 (27%), Positives = 97/198 (48%), Gaps = 35/198 (17%)
Query: 830 QILEALSYIHSQGIIHRDLKPMNIFIDESRNIKIGDFGLAK---NVQISQDTLRRDSFTS 886
+IL L ++H I+HRD+KP N+ I + +I I DFG A+ +Q+SQ+ + S
Sbjct: 180 EILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQAS 239
Query: 887 AGSSGD-------------------LTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIF 927
+ SS T+ +GTALYV+ E++ + G+ + D++ LG I
Sbjct: 240 SRSSDSGSPPPTRFYSDEEEENTARRTTFVGTALYVSPEML-ADGDVGPQTDIWGLGCIL 298
Query: 928 FEMI--YPFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTAS 985
F+ + P + + +++K+++ +D FP F ++ +II +L DP R T+
Sbjct: 299 FQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEE----ASEIIAKILVRDPSTRITSQ 354
Query: 986 ALL------RSGWVPVKN 997
L+ WV + N
Sbjct: 355 ELMAHKFFENVDWVNIAN 372
>At5g41990 [R] KOG0584 Serine/threonine protein kinase
Length = 608
Score = 76.6 bits (187), Expect = 3e-13
Identities = 118/468 (25%), Positives = 191/468 (40%), Gaps = 87/468 (18%)
Query: 829 RQILEALSYIHSQG--IIHRDLKPMNIFID-ESRNIKIGDFGLAKNVQISQDTLRRDSFT 885
RQIL+ L+Y+HSQ +IHRDLK NIF++ + +KIGD GLA +Q Q T R
Sbjct: 182 RQILKGLNYLHSQNPPVIHRDLKCDNIFVNGNTGEVKIGDLGLATVLQ--QPTAR----- 234
Query: 886 SAGSSGDLTSAIGTALYVASEIITSHGNYNEKVDMYSLGIIFFEMI---YPFDTGMERVN 942
S IGT ++A E+ YNE VD+YS G+ EM+ YP++ +
Sbjct: 235 ---------SVIGTPEFMAPELYEEE--YNELVDIYSFGMCMLEMVTCEYPYNECRNQAQ 283
Query: 943 VIKKL-RNIDVEFPSDFDDKKLHTEKKIIKLLLDHDPVRRPTASALLRSGWVPVKNQDEL 1001
+ KK+ NI + DD ++ + I K LL RPTA L + P +D
Sbjct: 284 IYKKVTSNIKPQSLGKVDDPQV--RQFIEKCLLPAS--SRPTALELSKD---PFLARDGG 336
Query: 1002 IKEALKNISDPSSPWQQQVRENLFTQPYHLSSDILFD----LSRSDTTPFLQLLRAQMVD 1057
AL S SS + + Q HL D+ + +S ++ P+ Q + Q +
Sbjct: 337 KDSALLASSSTSSKYVRP------PQLEHLPMDVDHNENKSVSSNEDYPWSQTIELQRIA 390
Query: 1058 EVIKIFRRHGAIENNEPPIIFPKAPIYSTQNVYEVLDRGGS------VLQLQYDLTYPMA 1111
E K FR G ++ + V + D G L+ D +A
Sbjct: 391 E-NKEFRLRG-----------ERSDDVTASMVLRIADPSGKCRIVHFAFYLESDTATAIA 438
Query: 1112 RYLSKNPNTTSKQ----------YRMQYVFRPSESTHSSTEPRKFGEVDFDIISNSSTDS 1161
+ + + TS++ + MQ + + S H+ PR E D + + + +S
Sbjct: 439 EEMVEELHLTSQEVVVIADMIDDFIMQLLSDRTSSHHNQNSPRLTHE-DHEAANQQTVNS 497
Query: 1162 AVHDAECLKVVDEIVST--FPVFTNTNTILVI--NHADILDGVFNFCNIDKAQRSLVSHM 1217
+A + +I + FP N + A+ + + C S M
Sbjct: 498 KDEEAAGQSMKSDISADYYFPYSANDGNAAMEAGRDAESMSSYLDSC----------SMM 547
Query: 1218 LSQLGFGRAFKDLKIDLRSQLNISSTSLND--LELFDFRSDLETSKKR 1263
+ + D DL+++LN+ + N +L + D + KR
Sbjct: 548 STIYNLSISDNDYPEDLKTELNLIESQFNQSFQDLLKLKEDAIENAKR 595
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 76.6 bits (187), Expect = 3e-13
Identities = 66/246 (26%), Positives = 119/246 (47%), Gaps = 34/246 (13%)
Query: 746 VSKASASEVTGLDSSKNDTLQEDGIGD-MKFGRDKRSKMK-----SLSVKSPRKSTLFIQ 799
V K SE+ + + D + E + MK RD +K+ L K L++
Sbjct: 151 VRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLV 210
Query: 800 MEYCENRTLYDLIHTESLNNQKEEYWRLFR-QILEALSYIHSQGIIHRDLKPMNIFIDES 858
+++ L+ ++ + L +E+ R++ +I+ A+S++H +GI+HRDLKP NI +D
Sbjct: 211 LDFINGGHLFFQLYHQGLF--REDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTD 268
Query: 859 RNIKIGDFGLAKNVQISQDTLRRDSFTSAGSSGDLTSAIGTALYVASEIITSHGNYNEKV 918
++ + DFGLAK + + + S GT Y+A EI+ G +++
Sbjct: 269 GHVMLTDFGLAKEFEENTRS---------------NSMCGTTEYMAPEIVRGKG-HDKAA 312
Query: 919 DMYSLGIIFFEMIY---PFDTGMERVNVIKKLRNIDVEFPSDFDDKKLHTEKKIIKLLLD 975
D +S+GI+ +EM+ PF ++ +K+ ++ P F + H I+K LL
Sbjct: 313 DWWSVGILLYEMLTGKPPFLGSKGKIQ--QKIVKDKIKLP-QFLSNEAHA---ILKGLLQ 366
Query: 976 HDPVRR 981
+P RR
Sbjct: 367 KEPERR 372
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.134 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,595,857
Number of Sequences: 60738
Number of extensions: 4014503
Number of successful extensions: 17609
Number of sequences better than 1.0e-05: 1260
Number of HSP's better than 0.0 without gapping: 243
Number of HSP's successfully gapped in prelim test: 1017
Number of HSP's that attempted gapping in prelim test: 14329
Number of HSP's gapped (non-prelim): 2843
length of query: 1672
length of database: 30,389,216
effective HSP length: 120
effective length of query: 1552
effective length of database: 23,100,656
effective search space: 35852218112
effective search space used: 35852218112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)