ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2654 good I KOG3030 Lipid transport and metabolism Lipid phosphate phosphatase and related enzymes of the PAP2 family
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2654 933311 932421 -297
(297 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR284c [I] KOG3030 Lipid phosphate phosphatase and related enzy... 350 1e-96
SPBC409.18 [I] KOG3030 Lipid phosphate phosphatase and related e... 171 1e-42
At1g15080 [I] KOG3030 Lipid phosphate phosphatase and related en... 112 5e-25
At3g18220 [I] KOG3030 Lipid phosphate phosphatase and related en... 110 2e-24
At3g02600 [I] KOG3030 Lipid phosphate phosphatase and related en... 110 2e-24
At2g01180 [I] KOG3030 Lipid phosphate phosphatase and related en... 108 9e-24
Hs20474788 [I] KOG3030 Lipid phosphate phosphatase and related e... 104 1e-22
7296728 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 103 4e-22
YDR503c [I] KOG3030 Lipid phosphate phosphatase and related enzy... 101 1e-21
Hs14210482 [I] KOG3030 Lipid phosphate phosphatase and related e... 87 3e-17
CE20846 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 86 5e-17
7296548 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 71 2e-12
7303897 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 71 2e-12
7296544 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 70 4e-12
ECU10g1440 [I] KOG3030 Lipid phosphate phosphatase and related e... 67 3e-11
Hs14721243 [I] KOG3030 Lipid phosphate phosphatase and related e... 65 1e-10
7296545 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 65 2e-10
Hs4505973 [I] KOG3030 Lipid phosphate phosphatase and related en... 60 3e-09
7296547 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 59 1e-08
HsM4505975 [I] KOG3030 Lipid phosphate phosphatase and related e... 58 1e-08
Hs21359834 [I] KOG3030 Lipid phosphate phosphatase and related e... 58 1e-08
Hs4505977 [I] KOG3030 Lipid phosphate phosphatase and related en... 54 4e-07
CE03202 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 53 6e-07
7303896 [I] KOG3030 Lipid phosphate phosphatase and related enzy... 52 1e-06
>YDR284c [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 289
Score = 350 bits (898), Expect = 1e-96
Identities = 167/271 (61%), Positives = 206/271 (75%), Gaps = 1/271 (0%)
Query: 21 KWKLTDLILCVVLFLVNIPVYYQKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVP 80
KW+L D+ L +++ L+N PVYYQ+PF+RQF+INDLTISHP+A E VNN+ L VYS+ VP
Sbjct: 16 KWRLEDVFLLIIMILLNYPVYYQQPFERQFYINDLTISHPYATTERVNNNMLFVYSFVVP 75
Query: 81 FFTIILFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPK 140
TI++ +LAD +H +++Y SLLGLS W STS TN++KNW GR RPDFL RC P
Sbjct: 76 SLTILIIGSILADRRHLIFILYTSLLGLSLAWFSTSFFTNFIKNWIGRLRPDFLDRCQPV 135
Query: 141 HGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPET 200
G P +TL A DVCT+ ++ L DGFRTTPSGHSSESFAGLG+L+ WLCGQLLTE P
Sbjct: 136 EGLPLDTLFTAKDVCTTKNHERLLDGFRTTPSGHSSESFAGLGYLYFWLCGQLLTESPLM 195
Query: 201 GSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVAHWSYRRYFPSIHSKLP 260
WR +VA LPL+GA++IALSRTQDYRHHFVDV+LGS+LG ++AH+ YRR FP I LP
Sbjct: 196 PLWRKMVAFLPLLGAALIALSRTQDYRHHFVDVILGSMLGYIMAHFFYRRIFPPIDDPLP 255
Query: 261 FKPLLDDSDVVLEEYSQVRSSGTDEELLPIS 291
FKPL+DDSDV LEE + DEEL P+S
Sbjct: 256 FKPLMDDSDVTLEE-AVTHQRIPDEELHPLS 285
>SPBC409.18 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 279
Score = 171 bits (433), Expect = 1e-42
Identities = 103/239 (43%), Positives = 135/239 (56%), Gaps = 8/239 (3%)
Query: 45 PFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTIILFSLLLADSKHRWYLMYIS 104
PF RQF + D+TISHPFA E V L + F P + F L +S L + S
Sbjct: 37 PFTRQFSLEDITISHPFALHEQVPTKYLGIICVFFPALVLYGFGKLRNNS----LLFWKS 92
Query: 105 LLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHGTPKNTLVYAIDVCTSTDYAVLY 164
L+GL ++ + L + LKN GR RPDFLARC P TPK LV + VL
Sbjct: 93 LMGLLYSTMVCGLCVSLLKNAVGRPRPDFLARCQPFESTPKTGLVDVLSCSVPWSDKVLQ 152
Query: 165 DGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQ 224
DGFR+ PSGH+S SFAGLGFL ++L GQL +T SW+ +V +PL AS I LSR+Q
Sbjct: 153 DGFRSFPSGHTSFSFAGLGFLAIFLAGQLKMFRNKTSSWKVVVPLVPLSIASWIGLSRSQ 212
Query: 225 DYRHHFVDVMLGSLLGILVAHWSYRRYFPSI-HSKLPFKPLLDDSDVVLEEYSQVRSSG 282
DYRHH D+ +G+L G +A+ YR+ FP + H + + D E Y+ V S+G
Sbjct: 213 DYRHHKEDIAVGALFGFAIAYVVYRQLFPPLDHHNADILYVQAELD---EGYTNVHSAG 268
>At1g15080 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 290
Score = 112 bits (281), Expect = 5e-25
Identities = 74/242 (30%), Positives = 133/242 (54%), Gaps = 18/242 (7%)
Query: 18 SLKKWKLTDLILCVVLFLVNIPVYYQKPFQRQFFINDLT-ISHPFAEVEMVNNHALIVYS 76
++ ++ + D ++ ++L ++ I + +PF R + LT + +P + + A+ + +
Sbjct: 17 TVARFHMHDWLILLLLIVIEIVLNVIEPFHRFVGEDMLTDLRYPLQD-NTIPFWAVPLIA 75
Query: 77 YFVPFFTIILFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLAR 136
+PF I ++ + D Y ++ ++LGL F+ + T ++T+ +K+ GR RPDF R
Sbjct: 76 VVLPFAVICVYYFIRNDV----YDLHHAILGLLFSVLITGVITDAIKDAVGRPRPDFFWR 131
Query: 137 CAPK-----HGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCG 191
C P H KN L CT V+ +G ++ PSGH+S SFAGLGFL L+L G
Sbjct: 132 CFPDGIGIFHNVTKNVL------CTGAK-DVVKEGHKSFPSGHTSWSFAGLGFLSLYLSG 184
Query: 192 QLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVAHWSYRRY 251
++ + + LPL+ A+++ +SR DY HH+ DV G+++G+ VA + Y ++
Sbjct: 185 KIRVFDQRGHVAKLCIVILPLLVAALVGVSRVDDYWHHWQDVFGGAIIGLTVATFCYLQF 244
Query: 252 FP 253
FP
Sbjct: 245 FP 246
>At3g18220 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 301
Score = 110 bits (276), Expect = 2e-24
Identities = 74/231 (32%), Positives = 125/231 (54%), Gaps = 15/231 (6%)
Query: 24 LTDLILCVVLFLVNIPVYYQKPFQRQFFINDLT-ISHPFAEVEMVNNHALIVYSYFVPFF 82
L D ++ VVL L++I + +PF R + LT ++ PF E + + A+ + VP
Sbjct: 23 LCDWLILVVLGLIDIVLNVIEPFHRYIGPDMLTDLTFPFYE-DTIPMWAVPIICILVPIC 81
Query: 83 TIILFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHG 142
I++ D Y ++ ++LG+ F+ + T + T+ +K+ GR RP+F RC P +G
Sbjct: 82 IFIVYYYYRRDV----YDLHHAILGIGFSCLVTGVTTDSIKDAVGRPRPNFFYRCFP-NG 136
Query: 143 TPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETGS 202
P DV ++ +G+++ PSGH+S SFAGL FL +L G++
Sbjct: 137 KP--------DVVCHGVKKIIKEGYKSFPSGHTSWSFAGLTFLAWYLSGKIKVFDRRGHV 188
Query: 203 WRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVAHWSYRRYFP 253
+ + LP++ + +I +SR DY HH+ DV G+++GI VA +SY +FP
Sbjct: 189 AKLCLVFLPILISILIGISRVDDYWHHWTDVFAGAIIGIFVASFSYLHFFP 239
>At3g02600 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 314
Score = 110 bits (276), Expect = 2e-24
Identities = 69/210 (32%), Positives = 119/210 (55%), Gaps = 14/210 (6%)
Query: 55 LTISHPFAEV---EMVNNHALIVYSYFVPFFTIILFSLLLA--------DSKHRWYLMYI 103
L I HPF +M+ + + + S VP +++ ++++LL + Y ++
Sbjct: 39 LLIIHPFYRFVGKDMMTDLSYPLKSNTVPIWSVPVYAMLLPLVIFIFIYFRRRDVYDLHH 98
Query: 104 SLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHGTPKNTLVYAIDVCTSTDYAVL 163
++LGL ++ + T++LT+ +KN GR RPDF RC P ++L DV D +V+
Sbjct: 99 AVLGLLYSVLVTAVLTDAIKNAVGRPRPDFFWRCFPDGKALYDSLG---DVICHGDKSVI 155
Query: 164 YDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRT 223
+G ++ PSGH+S SF+GLGFL L+L G++ + + + LPL+ A+++ +SR
Sbjct: 156 REGHKSFPSGHTSWSFSGLGFLSLYLSGKIQAFDGKGHVAKLCIVILPLLFAALVGISRV 215
Query: 224 QDYRHHFVDVMLGSLLGILVAHWSYRRYFP 253
DY HH+ DV G LLG+ ++ Y ++FP
Sbjct: 216 DDYWHHWQDVFAGGLLGLAISTICYLQFFP 245
>At2g01180 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 302
Score = 108 bits (270), Expect = 9e-24
Identities = 74/230 (32%), Positives = 121/230 (52%), Gaps = 9/230 (3%)
Query: 26 DLILCVVLFLVNIPVYYQKPFQRQFFINDLT-ISHPFAEVEMVNNHALIVYSYFVPFFTI 84
D I+ V+L + I + PF R + +T + +PF + V ++ VY+ +P
Sbjct: 25 DWIILVILIAIEIGLNLISPFYRYVGKDMMTDLKYPFKD-NTVPIWSVPVYAVLLPIIVF 83
Query: 85 ILFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHGTP 144
+ F L + Y ++ S+LGL F + T ++T+ +K GR RP+F RC P
Sbjct: 84 VCFYL----KRTCVYDLHHSILGLLFAVLITGVITDSIKVATGRPRPNFYWRCFPDGKEL 139
Query: 145 KNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETGSWR 204
+ L V A + +G ++ PSGH+S SFAGL FL L+L G++ E +
Sbjct: 140 YDALG---GVVCHGKAAEVKEGHKSFPSGHTSWSFAGLTFLSLYLSGKIKAFNNEGHVAK 196
Query: 205 TIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVAHWSYRRYFPS 254
+ PL+ A ++ +SR DY HH+ DV G+L+G LVA + YR+++P+
Sbjct: 197 LCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGTLVAAFCYRQFYPN 246
>Hs20474788 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 271
Score = 104 bits (260), Expect = 1e-22
Identities = 70/235 (29%), Positives = 116/235 (48%), Gaps = 13/235 (5%)
Query: 32 VLFLVNIPVYYQKPFQRQFFINDLTI-SHPFAEVEMVNNHALIVYSYFVPFFTIILFSLL 90
+LF V + + PFQR ++ + +P + + + + S+ P I + ++
Sbjct: 13 LLFGVFVFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII 72
Query: 91 LADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHGTPKNTLVY 150
K + + L +S + TN +K GR RPDF RC P V
Sbjct: 73 RRTDKTE---IKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDG-------VM 122
Query: 151 AIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQL--LTELPETGSWRTIVA 208
++ + D ++ +G ++ PS HSS +F+GLGF +L G+L TE SWR A
Sbjct: 123 NSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAA 182
Query: 209 CLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVAHWSYRRYFPSIHSKLPFKP 263
LPL A +IALSR DY+HH+ D +G ++G++ A+ YR+++P + + KP
Sbjct: 183 ILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKP 237
>7296728 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 412
Score = 103 bits (256), Expect = 4e-22
Identities = 73/239 (30%), Positives = 112/239 (46%), Gaps = 15/239 (6%)
Query: 26 DLILCVVLFLVNIPVYYQKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTII 85
D++L V+L + + F+R+ +L + ++V L+ + PF I
Sbjct: 123 DVVLRVLLVITFFKLETMTAFKREIHEEELWLYKNPRRPDIVRGGELLFWVIVAPFLVTI 182
Query: 86 LFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHGTPK 145
F D + + L L I TS+L K GR RPD+ RC P
Sbjct: 183 AFYWYTRDRRDFRAASWAWTLALCMNGIPTSVL----KITVGRPRPDYFYRCFPDGVMVL 238
Query: 146 NTLVYAIDV------CTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPE 199
NT +D CT + +G ++ PSGHSS +FA GF+ ++ G L
Sbjct: 239 NTTSNGVDTSILDFNCTGLP-GDINEGRKSFPSGHSSFAFASFGFIAYYI-GAKLHAFDS 296
Query: 200 TG---SWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVAHWSYRRYFPSI 255
G +WR +A +PL A ++A+SRT DY HH+ DV +G L+G+ + SY +Y+PSI
Sbjct: 297 RGRGHTWRLCIAVIPLFIALLVAVSRTCDYHHHWQDVTIGGLIGLFAGYISYTQYYPSI 355
>YDR503c [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 274
Score = 101 bits (251), Expect = 1e-21
Identities = 75/263 (28%), Positives = 134/263 (50%), Gaps = 26/263 (9%)
Query: 11 DRLKFYKSLKKWKLTDLILCVVLFLVNIPVYYQKPFQRQFFINDLTISHPFAEVEMVNNH 70
++ K Y L ++ + LC +LFL + + +F ++D +IS + E+V
Sbjct: 8 EKHKEYFKLYYFQYMIIGLCTILFLYSEISLVPRGQNIEFSLDDPSISKRYVPNELVGPL 67
Query: 71 ALIVYSY----FVPFFTIILFSLLLADSKHR------------WYLMYISLLGLSFTWIS 114
++ S V F+T + LL ++ + ++ M+ S+L L
Sbjct: 68 ECLILSVGLSNMVVFWTCMFDKDLLKKNRVKRLRERPDGISNDFHFMHTSILCLMLIISI 127
Query: 115 TSLLTNYLKNWFGRHRPDFLARCAP--KHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPS 172
+ LT LK G RPDF+ RC P + + ++LV+ +D+C T+ +LY+G ++TPS
Sbjct: 128 NAALTGALKLIIGNLRPDFVDRCIPDLQKMSDSDSLVFGLDICKQTNKWILYEGLKSTPS 187
Query: 173 GHSSESFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVD 232
GHSS + +GF +LW + T + R+ + C PL+ A V+ +SR D+RHH+ D
Sbjct: 188 GHSSFIVSTMGFTYLW------QRVFTTRNTRSCIWC-PLL-ALVVMVSRVIDHRHHWYD 239
Query: 233 VMLGSLLGILVAHWSYRRYFPSI 255
V+ G++L LV + ++ F ++
Sbjct: 240 VVSGAVLAFLVIYCCWKWTFTNL 262
>Hs14210482 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 175
Score = 87.0 bits (214), Expect = 3e-17
Identities = 62/175 (35%), Positives = 89/175 (50%), Gaps = 14/175 (8%)
Query: 59 HPFAEVEMVNNHALIVYSYFVPFFTIILFSLLL-ADSKHRWYLMYISLLGLSFTWISTSL 117
+P+ E E + V ++ P I L L AD++ + L L+ +
Sbjct: 6 NPYVEAEYFPTKPMFVIAFLSPLSLIFLAKFLKKADTRDSRQACLAASLALALNGV---- 61
Query: 118 LTNYLKNWFGRHRPDFLARCAPKHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSE 177
TN +K GR RPDF RC P + L ++ +CT D V+ +G ++ PSGHSS
Sbjct: 62 FTNTIKLIVGRPRPDFFYRCFP------DGLAHSDLMCTG-DKDVVNEGRKSFPSGHSSF 114
Query: 178 SFAGLGFLFLWLCGQLLTELPE--TGSWRTIVACLPLVGASVIALSRTQDYRHHF 230
+FAGL F +L G+L P+ SWR PL+ A+VIALSRT DY+HH+
Sbjct: 115 AFAGLAFASFYLAGKLHCFTPQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHW 169
>CE20846 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 346
Score = 86.3 bits (212), Expect = 5e-17
Identities = 76/263 (28%), Positives = 121/263 (45%), Gaps = 38/263 (14%)
Query: 28 ILC--VVLFLVNIPVY----YQKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPF 81
+LC +VL L+ IP+Y + P +R F+ +D +I +PF + + V LIV +P
Sbjct: 12 VLCDFLVLTLIAIPLYVFHEFIPPVRRGFYCDDESIRYPFRDSK-VTRQMLIVVGLLIPI 70
Query: 82 FTII---LFSLLLADSK---------------HRWYLMYISLLGLSFTWIS-TSLLTNYL 122
I+ LF L + K HR + +G F + L+ +
Sbjct: 71 LLILATELFRTLAWEKKCETEFKTYHVRNHSVHRLVVRLYCFIGYFFVGVCFNQLMVDIA 130
Query: 123 KNWFGRHRPDFLARCAPKHG--TPKNTLVYAIDV-CTSTDYAVLYDGFRTTPSGHSSESF 179
K GR RP F+ C P G T +Y D CT+TD +++ + SGHS+ SF
Sbjct: 131 KYTIGRQRPHFMDVCRPDIGYQTCSQPDLYITDFKCTTTDTKKIHEAQLSFYSGHSAFSF 190
Query: 180 AGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLL 239
F L+L +L L + ++ L GA+ ++L+R DY+HH+ DV++G+++
Sbjct: 191 YAAWFTSLYLQARLFRPL-FSRLLLPVIQFLLFGGAAYVSLTRVSDYKHHWSDVLVGAIM 249
Query: 240 G--------ILVAHWSYRRYFPS 254
G + VA RR PS
Sbjct: 250 GSAIGVFVALFVAEVFKRREIPS 272
>7296548 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 305
Score = 71.2 bits (173), Expect = 2e-12
Identities = 69/244 (28%), Positives = 114/244 (46%), Gaps = 37/244 (15%)
Query: 24 LTDLILCVVLFLV--NIPVYYQKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPF 81
L DL+L +L ++ N + P +R FF +D ++ +P+ E V+ L ++P
Sbjct: 14 LVDLVLLGLLIVLVENFRRLWGPPTKRGFFCDDESLMYPYHE-NTVSPTLLHWLGLYLPL 72
Query: 82 FTIILFSLLLADSKHR--W---YLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLAR 136
++++ L+ K W + +Y ++ + ++S LL K GR RP F A
Sbjct: 73 ISLVVLESFLSHRKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAV 132
Query: 137 CAPKHG--------TPKNTLVYAIDV-----CTSTDYAVLYDGFRTTPSGHSSESFAGLG 183
C+P + + L Y D + ++ D + PSGHS+ +F GL
Sbjct: 133 CSPHFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLV 192
Query: 184 FLFL------W-LCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLG 236
F+ L W L G LL+ + + +AC+ L A +A+SR DY+HH+ DV G
Sbjct: 193 FVALHLRRRRWPLRGSLLSPVLQ-------LACVAL--AWFVAISRVIDYKHHWSDVAAG 243
Query: 237 SLLG 240
SLLG
Sbjct: 244 SLLG 247
>7303897 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 372
Score = 70.9 bits (172), Expect = 2e-12
Identities = 70/269 (26%), Positives = 120/269 (44%), Gaps = 34/269 (12%)
Query: 27 LILCVVLFLVNIPVYYQKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTIIL 86
LIL F + + +P++R FF +D ++ HPF + V N L +P I +
Sbjct: 88 LILLCAGFPILLFFLLGEPYKRGFFCDDESLKHPFHD-STVRNWMLYFIGAVIPVGVIFI 146
Query: 87 FSLLLADSKHR--------------------WYLMYISLLGL-SFTWISTSLLTNYLKNW 125
++++ +K + W + +G+ +F + + L T+ K
Sbjct: 147 VEVIISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYS 206
Query: 126 FGRHRPDFLARCAPK--HGTPKNTLVYA---IDVCT----STDYAVLYDGFRTTPSGHSS 176
GR RP F+A C P+ G+ + + A I T + +L + + PSGHSS
Sbjct: 207 IGRLRPHFIAVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFPSGHSS 266
Query: 177 ESFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLG 236
+F + +L L+L ++ + R ++ L ++ A ALSR DY+HH+ DV+ G
Sbjct: 267 FTFFAMVYLALYLQARMTWRGSKL--LRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAG 324
Query: 237 SLLGILVAHWSYRRYFPSIHSKLPFKPLL 265
SL+G + A Y + K KP L
Sbjct: 325 SLIGSISA-LVVANYVSDLFQKPNTKPYL 352
>7296544 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 334
Score = 70.1 bits (170), Expect = 4e-12
Identities = 60/212 (28%), Positives = 103/212 (48%), Gaps = 15/212 (7%)
Query: 46 FQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTIILFSLLLADSKHRWYLMYISL 105
F+R FF +DL+I +P+ + + L++ +P + + ++ + R L + +L
Sbjct: 4 FKRGFFCSDLSIRYPYKDCT-ITVPMLLLMMLLLPMLFVAVVEIMRICKRFRTRLYFRNL 62
Query: 106 ----LGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPK--HGTP----KNTLVYAIDV- 154
SF +I+T L T K+ GR RP F C P+ G+ +N +Y
Sbjct: 63 WRAEATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGSSCSDLQNAELYVEQFH 122
Query: 155 CTSTDYAV--LYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPL 212
CT+ + + + + + PS HSS SF + L L++ G + R ++ L L
Sbjct: 123 CTNNNLSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHG-VWRGRGGVRVLRHVLQFLLL 181
Query: 213 VGASVIALSRTQDYRHHFVDVMLGSLLGILVA 244
+ A ++LSR DY HH+ DV+ G+LLG+ A
Sbjct: 182 MAALCVSLSRVADYWHHWSDVLAGALLGVTYA 213
>ECU10g1440 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 234
Score = 67.0 bits (162), Expect = 3e-11
Identities = 69/231 (29%), Positives = 104/231 (44%), Gaps = 25/231 (10%)
Query: 18 SLKKWKLTDLILCVVLFLVNIPVYYQKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSY 77
++ K LT I+ + L L++ V +P++R F I D +IS + + + S
Sbjct: 2 TMVKEMLTITIISMGLLLLSNSV---EPYKRPFDIGDESISRMYFRHDTITFIETAAVSV 58
Query: 78 FVPFFTIILFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARC 137
VP ++F+ +S R + +Y L + +++ N KN GR RPDFL+RC
Sbjct: 59 LVPL--ALMFATFRINSVERIHEIYFYASFLVTCLVGFAVVEN-TKNLAGRLRPDFLSRC 115
Query: 138 APKHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTEL 197
P G CT VL DG ++ PSGH+ S A GF+FL L + L
Sbjct: 116 NPVAGK-----------CTGNPLVVL-DGRKSFPSGHT--SIAACGFMFLALFISKESTL 161
Query: 198 P--ETGSWRTIVACLPLVGASV---IALSRTQDYRHHFVDVMLGSLLGILV 243
P + R+ V L V V + SR D +H DV+ G +G V
Sbjct: 162 PGLKAKVGRSSVFLLYFVFLMVPVAVGTSRVMDNKHFISDVIGGGAIGAFV 212
>Hs14721243 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 285
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/236 (28%), Positives = 110/236 (45%), Gaps = 28/236 (11%)
Query: 28 ILCVVLFLVNIPVYYQK-----PFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFF 82
+LCV+L ++P+ K PFQR FF D +I++P+ + V + LI+ +P
Sbjct: 14 VLCVLL--ASMPMAVLKLGQIYPFQRGFFCKDNSINYPYHD-STVTSTVLILVGVGLPIS 70
Query: 83 TIIL-------FSLLLADS--KHRWYLMYISLLG-LSFTWISTSLLTNYLKNWFGRHRPD 132
+IIL +LL ++S ++ + +G F ++ LT+ K GR RP
Sbjct: 71 SIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPH 130
Query: 133 FLARCAPKHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQ 192
FL C P + Y + + +G + SGHSS S + F+ L+L +
Sbjct: 131 FLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQAR 190
Query: 193 LLTELPETGSWRTIVAC---LPLVGASV-IALSRTQDYRHHFVDVMLGSLLGILVA 244
+ G W ++ LV S+ + LSR DY+HH+ DV+ G + G LVA
Sbjct: 191 M------KGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVA 240
>7296545 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 341
Score = 64.7 bits (156), Expect = 2e-10
Identities = 67/248 (27%), Positives = 111/248 (44%), Gaps = 35/248 (14%)
Query: 26 DLILCVVLFLVNIPVYYQ-KPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTI 84
DL++ V L + ++ ++ +PF+R FF D T+S+P A +++ +I VP I
Sbjct: 13 DLLIWVALSVASVLLHKMGRPFRRGFFCGDETLSYP-ARDGTISSKVIIAIVLGVPNAVI 71
Query: 85 ILFSLLLA-------------DS---KHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGR 128
++ L DS HR ++Y ++ + + T K GR
Sbjct: 72 VVVELFRQLPGGPLREAGGKRDSCRIAHRLGVLYRQVIFYLYGLAMVTFTTMLTKLCLGR 131
Query: 129 HRPDFLARCAP-----KHGTPKNTLVYAIDVCTS-----TDYAV--LYDGFRTTPSGHSS 176
RP FLA C P L ID T TDY LY F PSGH+S
Sbjct: 132 LRPHFLAVCQPMLPDGSSCQDAQNLGRYIDSFTCSNANMTDYQFKELYQSF---PSGHAS 188
Query: 177 ESFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLG 236
+ + +L ++L L T + + + ++ L ++ ++L+R DY HH+ DV+ G
Sbjct: 189 MAMYAMLYLAIYLQAALSTRVSKL--LKHLLQFLFVMFGWYVSLTRIIDYYHHWSDVLAG 246
Query: 237 SLLGILVA 244
+ LG++ A
Sbjct: 247 AALGVVFA 254
>Hs4505973 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 289
Score = 60.5 bits (145), Expect = 3e-09
Identities = 65/240 (27%), Positives = 108/240 (44%), Gaps = 32/240 (13%)
Query: 28 ILCVVLFLVNIPVYYQK-------PFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVP 80
+LCV+L + ++ + PFQR F ND +I +P+ E + +AL+ +P
Sbjct: 14 VLCVLLAGLPFAIFTSRHITSRHTPFQRGVFCNDESIKYPYKEDTIP--YALLG-GIIIP 70
Query: 81 FFTIILF---------SLLLADS--KHRWYLMYISLLG-LSFTWISTSLLTNYLKNWFGR 128
F I++ +LL ++S ++ + +G F ++ LT+ K GR
Sbjct: 71 FSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGR 130
Query: 129 HRPDFLARCAPKHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLW 188
RP FL C P + Y + + +G + SGHSS S + F+ L+
Sbjct: 131 LRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALY 190
Query: 189 LCGQLLTELPETGSWRTIVAC---LPLVGASV-IALSRTQDYRHHFVDVMLGSLLGILVA 244
L ++ G W ++ LV S+ + LSR DY+HH+ DV+ G + G LVA
Sbjct: 191 LQARM------KGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVA 244
>7296547 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 340
Score = 58.5 bits (140), Expect = 1e-08
Identities = 71/258 (27%), Positives = 110/258 (42%), Gaps = 41/258 (15%)
Query: 28 ILCVVLFLVNIPVYY--QKPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTII 85
+L VV+ ++ I VY P +R FF +D +IS+PF + + L + +P ++
Sbjct: 42 LLVVVVLVIPICVYEFAVDPVRRGFFCDDESISYPFQD-NTITPVMLGLIVGLLPALVMV 100
Query: 86 LFSL--------------LLADSKHRWYLMYISLLGLSFTWISTSLL-----TNYLKNWF 126
+ LL WY+ LG T+ LL T K
Sbjct: 101 VVEYVSHLRAGDISATVDLLGWRVSTWYVE----LGRQSTYFCFGLLLTFDATEVGKYTI 156
Query: 127 GRHRPDFLARCAPKHGT------PKNTLVYAIDV-CTSTDYAV--LYDGFRTTPSGHSSE 177
GR RP FLA C P+ P N Y + C + V + + PSGHSS
Sbjct: 157 GRLRPHFLAVCQPQIADGSMCSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSL 216
Query: 178 SFAGLGFLFLWLCGQLLTELPETGSWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGS 237
+F + ++ L+L ++ + R V ++ A ALSR D+ HH+ DV+ GS
Sbjct: 217 AFYAMIYVALYLQRKITWRGSKLS--RHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGS 274
Query: 238 LLGI----LVAHWSYRRY 251
LLG+ + AH+ R +
Sbjct: 275 LLGVAGALITAHYIARMF 292
>HsM4505975 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 311
Score = 58.2 bits (139), Expect = 1e-08
Identities = 61/241 (25%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 27 LILCV---VLFLVNIPVYYQ-----KPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYF 78
L++C+ LF+ +P KP+ R F+ ND +I +P E +N+ L
Sbjct: 35 LLICLDLFCLFMAGLPFLIIETSTIKPYHRGFYCNDESIKYPLKTGETINDAVLCAVGIV 94
Query: 79 VPFFTIILFSL----LLADSKHRWYLMYISLL-----GLSFTWISTSLLTNYLKNWFGRH 129
+ II L S+ Y++ L F + T+ K GR
Sbjct: 95 IAILAIITGEFYRIYYLKKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRL 154
Query: 130 RPDFLARCAPKHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWL 189
RP FL+ C P + Y + D + + + ++ SGH+S S + +L L+L
Sbjct: 155 RPHFLSVCNPDFSQINCSEGYIQNYRCRGDDSKVQEARKSFFSGHASFSMYTMLYLVLYL 214
Query: 190 CGQLLTELPETGSWRTIVACLPLVGASVI------ALSRTQDYRHHFVDVMLGSLLGILV 243
+ +WR PL+ ++I LSR D++HH DV+ G G LV
Sbjct: 215 QARF--------TWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALV 266
Query: 244 A 244
A
Sbjct: 267 A 267
>Hs21359834 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 311
Score = 58.2 bits (139), Expect = 1e-08
Identities = 61/241 (25%), Positives = 98/241 (40%), Gaps = 31/241 (12%)
Query: 27 LILCV---VLFLVNIPVYYQ-----KPFQRQFFINDLTISHPFAEVEMVNNHALIVYSYF 78
L++C+ LF+ +P KP+ R F+ ND +I +P E +N+ L
Sbjct: 35 LLICLDLFCLFMAGLPFLIIETSTIKPYHRGFYCNDESIKYPLKTGETINDAVLCAVGIV 94
Query: 79 VPFFTIILFSL----LLADSKHRWYLMYISLL-----GLSFTWISTSLLTNYLKNWFGRH 129
+ II L S+ Y++ L F + T+ K GR
Sbjct: 95 IAILAIITGEFYRIYYLKKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRL 154
Query: 130 RPDFLARCAPKHGTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWL 189
RP FL+ C P + Y + D + + + ++ SGH+S S + +L L+L
Sbjct: 155 RPHFLSVCNPDFSQINCSEGYIQNYRCRGDDSKVQEARKSFFSGHASFSMYTMLYLVLYL 214
Query: 190 CGQLLTELPETGSWRTIVACLPLVGASVI------ALSRTQDYRHHFVDVMLGSLLGILV 243
+ +WR PL+ ++I LSR D++HH DV+ G G LV
Sbjct: 215 QARF--------TWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALV 266
Query: 244 A 244
A
Sbjct: 267 A 267
>Hs4505977 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 288
Score = 53.5 bits (127), Expect = 4e-07
Identities = 58/223 (26%), Positives = 95/223 (42%), Gaps = 20/223 (8%)
Query: 32 VLFLVNIPVYYQKPFQRQFFINDLTISHPF----------AEVEMVNNHALIVYSYFVPF 81
+L LVN P ++R F+ D +I +P+ A V + L+
Sbjct: 24 ILTLVNAP------YKRGFYCGDDSIRYPYRPDTITHGLMAGVTITATVILVSAGEAYLV 77
Query: 82 FTIILFSLLLADSKHRWYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKH 141
+T L+S +D + +Y L F + LT+ K GR RP+FLA C P
Sbjct: 78 YTDRLYSR--SDFNNYVAAVYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPNFLAVCDPDW 135
Query: 142 GTPKNTLVYAIDVCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETG 201
++ ++ + A + + + SGHSS + FL L++ +L +
Sbjct: 136 SRVNCSVYVQLEKVCRGNPADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKWARL- 194
Query: 202 SWRTIVACLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVA 244
R V + A + +R DY+HH+ DV++G L G LVA
Sbjct: 195 -LRPTVQFFLVAFALYVGYTRVSDYKHHWSDVLVGLLQGALVA 236
>CE03202 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 318
Score = 52.8 bits (125), Expect = 6e-07
Identities = 50/211 (23%), Positives = 94/211 (43%), Gaps = 14/211 (6%)
Query: 45 PFQRQFFINDLTISHPFAEVEMVNNHALIVYSYFVPFFTIILFSLLL---ADSKHRWYLM 101
P++R D++I PF E + H L++ + PF + L +L + +R
Sbjct: 77 PYERAMPCGDISIQQPFKENTVGLKHLLVI-TLGSPFLIVALVEAILHFKSKGSNRLAKF 135
Query: 102 Y----ISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAPKHG----TPKNTLVYAID 153
+ I+ L + + + +LK + GR RP F + C P T K + + + D
Sbjct: 136 FSATTITYLKYLLMYAACTFAMEFLKCYVGRLRPHFFSVCKPDWSKVDCTDKQSFIDSSD 195
Query: 154 -VCTSTDYAVLYDGFRTTPSGHSSESFAGLGFLFLWLCGQL-LTELPETGSWRTIVACLP 211
VCT+ + + + PSGH++ +F F++++L T + E + R I+
Sbjct: 196 LVCTNPNPRKIRTARTSFPSGHTAAAFHVFLFVYIYLRRMAENTGIKEIITIRNILVPSY 255
Query: 212 LVGASVIALSRTQDYRHHFVDVMLGSLLGIL 242
+ A++R D H DV+ G +L ++
Sbjct: 256 ALWTVFCAVTRVTDNWHFPTDVLGGVILAVV 286
>7303896 [I] KOG3030 Lipid phosphate phosphatase and related enzymes of the
PAP2 family
Length = 246
Score = 52.0 bits (123), Expect = 1e-06
Identities = 50/156 (32%), Positives = 71/156 (45%), Gaps = 15/156 (9%)
Query: 98 WYLMYISLLGLSFTWISTSLLTNYLKNWFGRHRPDFLARCAP--KHGT----PKNTLVYA 151
++ M I + GL +ST N K GR RP F C P K GT P N Y
Sbjct: 89 YHRMGIFIFGLGVEQLST----NIAKYSIGRLRPHFYTLCQPVMKDGTTCSDPINAARYI 144
Query: 152 ID-VCTSTDYAV--LYDGFRTTPSGHSSESFAGLGFLFLWLCGQLLTELPETGSWRTIVA 208
+ C + D L D + PSGH+S FA L+L + + + ++
Sbjct: 145 EEFTCAAVDITSKQLKDMRLSFPSGHAS--FACYSMLYLVIYLHRRMQWKQLRMLCHLLQ 202
Query: 209 CLPLVGASVIALSRTQDYRHHFVDVMLGSLLGILVA 244
L L+ A AL+R DY+HH+ DV+ GS +G+ A
Sbjct: 203 FLLLMFAWYTALTRVSDYKHHWSDVLAGSGIGLTYA 238
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.141 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,740,244
Number of Sequences: 60738
Number of extensions: 799397
Number of successful extensions: 2282
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2222
Number of HSP's gapped (non-prelim): 28
length of query: 297
length of database: 30,389,216
effective HSP length: 106
effective length of query: 191
effective length of database: 23,950,988
effective search space: 4574638708
effective search space used: 4574638708
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)