ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2663 suspect: %id U KOG0946 Intracellular trafficking, secretion, and vesicular transport ER-Golgi vesicle-tethering protein p115
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2663 936212 938476 755
(755 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115 77 7e-14
YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein 61 7e-09
SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil pr... 58 6e-08
SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil p... 57 8e-08
SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115 54 7e-07
Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein 54 9e-07
7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related... 54 9e-07
Hs11321579 [Z] KOG0161 Myosin class II heavy chain 52 3e-06
CE00283 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin deg... 51 6e-06
>YDL058w [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1790
Score = 77.4 bits (189), Expect = 7e-14
Identities = 101/435 (23%), Positives = 188/435 (43%), Gaps = 79/435 (18%)
Query: 272 KYTELLQQLSTSKKEITAEIQECFNKVEATSNT---RVDTLQNYVNSRLQAICENIK--- 325
K TE L+ L+ + K++ AE + VE + N ++ LQN ++S Q EN +
Sbjct: 959 KLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEK-ENFQIER 1017
Query: 326 ---EANVDIAKGLGMDLNQKTEKLIS-----------ELGVVKDSVSTAATSTTEIIMHE 371
E N++ K DL Q E++IS ++ ++K+ + TA T+ E + ++
Sbjct: 1018 GSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKLETATTANDENV-NK 1076
Query: 372 VNKLYVTLPHIE-------NIVSEL-----------KEMTANNGTLTMEFIT-SAFLSSV 412
+++L T +E N+ +EL KE+ N L E I +
Sbjct: 1077 ISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEEKIQLEKEATET 1136
Query: 413 DTLLKTLQVSMESLQK----LPDAICTLDNKITSAEG-FENEINALKEEVHTTMLQKTET 467
L +L+ ++ESL+K L + + +I + E + EI+ L +E+ +T + E
Sbjct: 1137 KQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITST---QQEN 1193
Query: 468 VSMLRSKDHXXXXXXXXXXXXXXXXXXXXDKNAILQTEFSSITVSNEAYVREITRIKKEN 527
S+ + D +++ + ++E ++ + ++E+ + + N
Sbjct: 1194 ESIKKKNDELEGEVKAMKSTSE-------EQSNLKKSEIDALNLQ----IKELKKKNETN 1242
Query: 528 EEAITSLDSKLTAQTEISSILQKDMNDTKKEIDSLKKKHTQALDENNSIKHKYENLQQQF 587
E ++ + ++T LQ + N +KE+ L+ K + D+N+ KY LQ++
Sbjct: 1243 EASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNS----KYLELQKES 1298
Query: 588 HKINVEL--------VQ-------SKAKELEFGEINRNLREQFEELESASNHTSNSFKRV 632
KI EL +Q SKAKE E++R + EE ++A +
Sbjct: 1299 EKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEI 1358
Query: 633 NDKVHALEKEKSALN 647
K A EKE+ LN
Sbjct: 1359 QIKNQAFEKERKLLN 1373
Score = 60.5 bits (145), Expect = 9e-09
Identities = 99/511 (19%), Positives = 192/511 (37%), Gaps = 41/511 (8%)
Query: 163 QYKAEILAVTEKIHVHKNLLSLLEDQIKGLKHSKSENDSLIAELGDSYKLLNEKVKSSIA 222
Q EI + ++ K LE ++K +K + E +L D+ L +++K
Sbjct: 1181 QLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNE 1240
Query: 223 ESEALKITXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCSGQLSEEKIKYTELLQQLST 282
+EA + ++ KY EL ++
Sbjct: 1241 TNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEK 1300
Query: 283 SKKEITAEIQECFNKVEATSNTRVDTLQNYVNSRLQAI----CENIKEANVDIAKGLGMD 338
K+E+ A+ E K++ T + + S L + E K A + K L +
Sbjct: 1301 IKEELDAKTTEL--KIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEK-LKNE 1357
Query: 339 LNQKTEKLISELGVVKDSVSTAATSTTEIIMHEVNKLYVTLPHIENIVSELKEMTANNGT 398
+ K + E ++ + ST +E ++N L L ++N +ELK +N
Sbjct: 1358 IQIKNQAFEKERKLLNEGSSTITQEYSE----KINTLEDELIRLQN-ENELKAKEIDNTR 1412
Query: 399 LTMEFITSAFLSSVDTLLKTLQVSMESLQ----KLPDAICTLDNKITSAE-GFENEINAL 453
+E ++ S D LL+ Q +++SLQ D I D K+ S E + ++ +L
Sbjct: 1413 SELEKVSL----SNDELLEEKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESL 1468
Query: 454 KEEVHTTMLQKTETVSMLRSKDHXXXXXXXXXXXXXXXXXXXXDKNAILQTEFSSITVSN 513
KE++ K + L+ + +TE S +
Sbjct: 1469 KEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETI 1528
Query: 514 EAYVREITRIKKENEEAITSLD-----------------SKLTAQTEISSILQKDMNDTK 556
++ + KK EE I +L +L ++ I + ++ K
Sbjct: 1529 RKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVK 1588
Query: 557 KEIDSLKKKHTQALDENNSIKHKYENLQQQFHKINVELVQSKAKELEFGEINRNLREQFE 616
+E+++ ++K +EN +K K E+++++ E ++S +E E + L+E +
Sbjct: 1589 QELNNAQEKIRINAEENTVLKSKLEDIERELKDKQAE-IKSNQEEKEL--LTSRLKELEQ 1645
Query: 617 ELESASNHTSNSFKRVNDKVHALEKEKSALN 647
EL+S S + +V + EKS L+
Sbjct: 1646 ELDSTQQKAQKSEEERRAEVRKFQVEKSQLD 1676
>YKR095w [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1875
Score = 60.8 bits (146), Expect = 7e-09
Identities = 97/492 (19%), Positives = 205/492 (40%), Gaps = 64/492 (13%)
Query: 171 VTEKIHVHKNLLSLLEDQIKGLKHSKSENDSLIAELGDSYKLLNEKVKSSIAESEALKIT 230
VTE++ KN++ L E + LK ++ L D + +K K S+ + E+ +
Sbjct: 529 VTERLVEFKNIIQLQEKNAELLK--------VVRNLADKLESKEKKSKQSLQKIESETVN 580
Query: 231 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCSGQLSEEKIKYTEL-LQQLSTSKKEITA 289
S + E Y+ + ++QL+ +K+++ +
Sbjct: 581 EAKEAIITLKSEKMDLESRIEELQKELEELKTS--VPNEDASYSNVTIKQLTETKRDLES 638
Query: 290 EIQECFNKVEATSNTRVDTLQNYVNSRLQAICENIKEANVDIAKGLGMDLNQKTEKLISE 349
++Q+ ++ + + + + +N +Q + ++ + ++ + K +K+ ++++E
Sbjct: 639 QVQDLQTRISQITRESTENM-SLLNKEIQDLYDSKSDISIKLGK-------EKSSRILAE 690
Query: 350 LGVVKDSVSTAATSTTEIIMHEVNKLYVTLPHIENIVSELKEMTANNGTLTMEFITSAFL 409
++T ++ E ++L +++N + LK+ + + TL + L
Sbjct: 691 ------ERFKLLSNTLDLTKAENDQLRKRFDYLQNTI--LKQDSKTHETLNEYVSCKSKL 742
Query: 410 SSVDTLL------KTLQVSMES-----LQKLPDAICTLDNKITSAEGFENEINALKEEVH 458
S V+T L + L+V +E L KL +L +T + + E L EE
Sbjct: 743 SIVETELLNLKEEQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKEREDLLEETR 802
Query: 459 TTMLQKTETVSMLRSKDHXXXXXXXXXXXXXXXXXXXXDKNAILQTEFSSITVSNEAYVR 518
+ +K + + +D D N+ + E Y
Sbjct: 803 KSCQKKIDEL-----EDALSELKKETSQKDHHIKQLEEDNNSNI-----------EWYQN 846
Query: 519 EITRIKKENEEAITSLDSKLTAQTEISSILQKDMNDTKKEIDSLK-KKHT-QALDENNSI 576
+I +KK+ E ITS+DSK QT+I LQ + +KEI+ K + HT +DE +
Sbjct: 847 KIEALKKDYESVITSVDSK---QTDIEK-LQYKVKSLEKEIEEDKIRLHTYNVMDETIND 902
Query: 577 KHKYENLQQQFHKINVELVQSKAKELE--FGEINRNLREQFEELESASNHTSNSFKRVND 634
+ L++ KIN+ S+ KE + + +++L++ +L+ + +N K + D
Sbjct: 903 DSLRKELEKS--KINLTDAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTD 960
Query: 635 KVHALEKEKSAL 646
+ +LE + S L
Sbjct: 961 EKTSLEDKISLL 972
>SPAC1F3.06c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1957
Score = 57.8 bits (138), Expect = 6e-08
Identities = 123/615 (20%), Positives = 236/615 (38%), Gaps = 98/615 (15%)
Query: 185 LEDQIKGLKHSKSENDSL---IAELGDSYKLLNEKVKSSIAESEALKITXXXXXXXXXXX 241
LE+ K L + + DSL I L + + E ++ S E++ L+
Sbjct: 670 LEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLEAKNLREVIDNLKGKHETL 729
Query: 242 XXXXXXXXXXXXXXXXXXXXCSGQL---SEEKIKYTELLQQLSTSKKEITAEIQECFNKV 298
S +L SE+ + T ++ L+ K + N
Sbjct: 730 EAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSY 789
Query: 299 EATSNTRVDTLQNYVN------------SRLQAICENIKEANV----DIAKGLGMDLNQK 342
++ SN + ++VN S+L+ CEN+ + N+ ++ K + +NQ+
Sbjct: 790 QSISNLYHELRDDHVNMQSQNNTLLESESKLKTDCENLTQQNMTLIDNVQKLMHKHVNQE 849
Query: 343 TEKLISELGVVKDSVSTAATSTTEIIMHEVNKLYVTLPHIENIVSELKEMTANNGTLTME 402
++ +SEL V +S + + L V + + I+++L E++ N +L E
Sbjct: 850 SK--VSELKEVNGKLSLDLKNLR-------SSLNVAISDNDQILTQLAELSKNYDSLEQE 900
Query: 403 FIT-SAFLSSVDTLLKTLQVSMESLQKLPDAIC-----------TLDNKITSAEGFENEI 450
++ L S++ + L E L D + L K+T+ + EI
Sbjct: 901 SAQLNSGLKSLEAEKQLLHTENEELHIRLDKLTGKLKIEESKSSDLGKKLTARQ---EEI 957
Query: 451 NALKEEVHTTMLQKTETVSMLRSKDHXXXXXXXXXXXXXXXXXXXXDKNAILQTEFSSIT 510
+ LKEE + +++ ++ ++SK +K + ++ E +++
Sbjct: 958 SNLKEE----NMSQSQAITSVKSK---LDETLSKSSKLEADIEHLKNKVSEVEVERNALL 1010
Query: 511 VSNEAYVREI-----------TRIKKENEEAITSLDSKLTAQTE-------ISSILQKDM 552
SNE + ++ T I+K+ E L SKL+ + ISS K +
Sbjct: 1011 ASNERLMDDLKNNGENIASLQTEIEKKRAEN-DDLQSKLSVVSSEYENLLLISSQTNKSL 1069
Query: 553 NDTKKEIDSLKKKHTQALDENNSIKHKYENLQQQFHKINVELVQSKAKELEFGEINR--- 609
D ++ ++K + LDE + + E L ++ K+ E Q K + L + ++
Sbjct: 1070 EDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRKKSKKQH 1129
Query: 610 --------NLREQFEELESASNHTSN---SFKRVNDKVHALEKEKSAL-NXXXXXXXXXX 657
+L+E+ + LE +N + S ++ N AL +E+S L N
Sbjct: 1130 DLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSDMKKSLS 1189
Query: 658 XXXXXXXXXANNQNRSNSNLDPPKR---KISSTQQKIIEDDAFALSSDDL--ELTNPEYS 712
++ R N LD K+ +S+ ++ +D DDL L E S
Sbjct: 1190 DSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQD------RDDLLDSLKGCEES 1243
Query: 713 MLMKPVEARRMPSKS 727
V R + +KS
Sbjct: 1244 FNKYAVSLRELCTKS 1258
>SPAC1486.04c [S] KOG4674 Uncharacterized conserved coiled-coil protein
Length = 1727
Score = 57.4 bits (137), Expect = 8e-08
Identities = 87/457 (19%), Positives = 185/457 (40%), Gaps = 51/457 (11%)
Query: 277 LQQLSTSKKEITAEIQECFNKVEATSNTR-VDTLQNYVNSRLQAICENIKEANVDIAKGL 335
L++ S + A++Q + + +S + V NY+N + + E+N + + L
Sbjct: 1192 LKRTVESSNRVIADLQRGITEKDVSSTSESVGERSNYLN-----MVALLNESNKSLRENL 1246
Query: 336 GMDLNQKTEKLISELGVVKDSVSTAATSTTEIIMHEV---NKLYVTLPHIENIVSELKEM 392
++ E++I+EL ++ + T T +++ ++L ++ + + +E
Sbjct: 1247 -----ERNEEVITEL---REKIETLKTDLANFRLNKEQLESQLQTEKAAVKKLENSNEEY 1298
Query: 393 TANNGTLTMEFITSAFLSSVDTLLKTLQVSMESL-----QKLPDAICTLDNKITSAEGFE 447
+N + + +S SS + LK VS E+L Q++ L+ + +E E
Sbjct: 1299 KRHNQEILLSLNSSTSTSSDASRLKNELVSKENLIEELNQEIGHLKSELETVKSKSEDLE 1358
Query: 448 NEINALKEEVHTTMLQKTETVSMLRSKDHXXXXXXXXXXXXXXXXXXXXDKNAILQTEFS 507
NE + ++ L+ T+ + R+K +K+ ++ + S
Sbjct: 1359 NERAQNQSKIEQLELKNTKLAAAWRTK-------------YEQVVNKSLEKHNQIRQQLS 1405
Query: 508 SITVSNEAYVREITRIKKENEEAITSLDSKLTAQTEISSILQKDMNDTKKEIDSLKKKHT 567
T EA V E ++ ++ + S T Q+E S++ ++ N TK+E+ S ++K +
Sbjct: 1406 QKTSELEAKVAECHQLNEQLNKP--SATPTATTQSEPSTVSLEEFNSTKEELSSTQRKLS 1463
Query: 568 QALDENNSIKHKYENLQQQFHKINVELVQSKAKELEFGEINRNLREQFEELES--ASNHT 625
+ +D N+ K + E ++Q +K ++ E E + ++++ L S A
Sbjct: 1464 EIMDILNTTKEELEKVRQNSNKSEGTSKDTEIPNEEEMERKKVMQQEVLRLRSRIAKELQ 1523
Query: 626 SNSFKRVNDKVHALEKEKSALNXXXXXXXXXXXXXXXXXXXANNQNRSNSNLDPPKRKIS 685
N R ++V L+ + AL + + NL + +S
Sbjct: 1524 KNELLRKQNQV--LQDQVKALQ------ETVVSSEEAESASVHADTKDLENLKKTEEMLS 1575
Query: 686 STQQKIIEDDAFALSSDDLELTNPEYSMLMKPVEARR 722
T Q I + S+ + T + + K E RR
Sbjct: 1576 VTFQVIFNESISDFSTSTADFT----TFVQKEWEKRR 1608
>SPAC29E6.03C [U] KOG0946 ER-Golgi vesicle-tethering protein p115
Length = 1044
Score = 54.3 bits (129), Expect = 7e-07
Identities = 72/391 (18%), Positives = 164/391 (41%), Gaps = 30/391 (7%)
Query: 266 LSEEKIKYTELLQQLSTSKKEITAEIQECFNKVEATSNTRVDTLQNYVNSRLQ-----AI 320
+ E I+ +L + L TSK + + Q E +D Q + R++ +
Sbjct: 626 VKERSIQEEKLNESLKTSKTNLEEQTQ----LAEKYHEELLDNQQKLYDLRIELDYTKSN 681
Query: 321 CENIKEANVDIAKGLGMDLNQKTE---KLISELGVVKDSVSTAATSTTEIIMHEVNKLYV 377
C+ ++E + +G ++ E KL +L +K+ ++ +++ E+ K
Sbjct: 682 CKQMEEEMQVLREGHESEIKDFIEEHSKLTKQLDDIKNQFGIISSKNRDLLS-ELEKSKS 740
Query: 378 TLPHIENIVSELKEMTANNGTLTMEFITSAFLSSVDTLLKTLQVSMESLQKLPDAICTLD 437
+ + S+ K++ + LT + + ++ T++ + S + L D + +
Sbjct: 741 LNNSLAALESKNKKLENDLNLLTEKLNKKN--ADTESFKNTIREAELSKKALNDNLGNKE 798
Query: 438 NKITSAEGFENEINALKEEVHTTMLQKTETVSMLRSKDHXXXXXXXXXXXXXXXXXXXXD 497
N I+ + +E + +E+ + + Q + L + +
Sbjct: 799 NIISDLKNKLSEESTRLQELQSQLNQDKNQIETLNER--------ISAAADELSSMESIN 850
Query: 498 KNAILQTEFSSITVSN-EAYVREITRIKKENEEAITSLDSKLTAQTEISSILQKDMNDTK 556
KN + + + SN + + ++ KE+ E I+SL+ L A T+ +S L K++ K
Sbjct: 851 KNQANELKLAKQKCSNLQEKINFGNKLAKEHTEKISSLEKDLEAATKTASTLSKELKTVK 910
Query: 557 KEIDSLKKKHTQALDENNSIKH-KYENLQQQFHKINVELVQSKAKELEFGEIN----RNL 611
E DSLK ++ S+ + K++ + Q + N E + ++ +E+E +++ +N
Sbjct: 911 SENDSLKSVSNDDQNKEKSVNNEKFKEVSQALAEAN-EKLNARDEEIERLKVDIIGLQNA 969
Query: 612 REQFEELESASNHTSNSFKRVNDKVHALEKE 642
+ L+ + N T + + N ++ KE
Sbjct: 970 SLNMQSLKDSDNRTISDLESKNKELEKKLKE 1000
>Hs8923838 [S] KOG4643 Uncharacterized coiled-coil protein
Length = 742
Score = 53.9 bits (128), Expect = 9e-07
Identities = 87/399 (21%), Positives = 166/399 (40%), Gaps = 38/399 (9%)
Query: 265 QLSEEKIKYTELLQQLSTSKKEITAEIQECFNKVEATSNTRVDTLQNYVNSRLQAICENI 324
+L E +Y E L + K + E++E N+V + T ++ +R + E
Sbjct: 249 KLESEVSRYKERLHDIEFYKARVE-ELKED-NQVLLETKTMLEDQLEGTRARSDKLHELE 306
Query: 325 KEANVDIAKGLGMDLNQKTE-KLISELGVVKDSVSTAATSTTEIIMHEVNKLYVTLPHIE 383
KE AK M++ + + K I EL ++ A + + +H L L I
Sbjct: 307 KENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLH----LGWELEQIS 362
Query: 384 NIVSELKEMTANNGTLTMEFITSAFLSSVDTLLKTLQVSMESLQKLPDAICTLDNKITSA 443
SEL E + + +TS+ L ++ ++L ++E L+ D++ +KI
Sbjct: 363 R-TSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKM 421
Query: 444 EGFENEINALKEEVHTTMLQKTETVS--------MLRSKDHXXXXXXXXXXXXXXXXXXX 495
E ++ E + ++Q+ +++ +++ K
Sbjct: 422 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 481
Query: 496 XDKNAILQTEFSSIT----VSNEAYVREITRIKKENEEAITSLDSKLTAQTEISSILQKD 551
+N L SS+ +S EA V++I + K E+I SKL S ++ +
Sbjct: 482 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL-------SKIEFE 534
Query: 552 MNDTKKEIDSLKKKHTQALDENNSIKH---KYENLQQQFHKINVELVQSKAKELEFGEIN 608
KKE++ K+K +A + N + H + E LQ++ + + + +A E E E+
Sbjct: 535 KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELE 594
Query: 609 RNLREQFEELESASNHTSNSFKRVNDKVHALEKEKSALN 647
R R+ + L+S FK + ++ +LEKE S L+
Sbjct: 595 RENRKLKKTLDS--------FKNLTFQLESLEKENSQLD 625
>7298379 [ZR] KOG4568 Cytoskeleton-associated protein and related proteins
Length = 1690
Score = 53.9 bits (128), Expect = 9e-07
Identities = 99/517 (19%), Positives = 200/517 (38%), Gaps = 48/517 (9%)
Query: 171 VTEKIHVHKNLLSLLEDQIKGLKHSKSENDSLIAELGDSYKLLNEKVKSSIAESEALKIT 230
VT +++V K S L+D ++ K E +L+ + E+ ++ + E L+
Sbjct: 641 VTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQ 700
Query: 231 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCSGQLSEEKIKYTELLQQLSTSK---KEI 287
QL+ ++ + + ++ S S+ +EI
Sbjct: 701 ISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI 760
Query: 288 TAE-IQECFNKVEATSNTRVDTLQNYV------NSRLQAICENIKEANVDIAKGLGMDLN 340
A+ Q+ F VE S + LQ + + +LQA E +K+ I K +L
Sbjct: 761 KAQNTQKDFELVE--SGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQ 818
Query: 341 Q------KTEKLISELGVVKDSVSTAATSTTEIIMHEVNKLYVTLPHIE----------- 383
Q ++E + + V + + A ++ E V KL+ + ++
Sbjct: 819 QLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELK 878
Query: 384 ----NIVSELKEMTANNGTLTMEFITSAFLSSVDTLLKTLQVSMESLQKLPDAICTLDNK 439
N+ ++ K++ A NG+L E S L T LK+ +V E+ L +++K
Sbjct: 879 STQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKS-EVG-ETQAALSSCHTDVESK 936
Query: 440 ITSAEGFENEINALKEEVHTTMLQKTETVSMLRSK-----DHXXXXXXXXXXXXXXXXXX 494
E NA E+V+ + S L+ K D
Sbjct: 937 TKQLEA----ANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTK 992
Query: 495 XXDKNAILQTEFSSITVSNEAYVREITRIKKENEEAITSLDSKLTAQTEISSILQKDMND 554
+ + T +T +A+ +E+ + +KE +E L +QT++ + ++
Sbjct: 993 LSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKS 1052
Query: 555 TKKEIDSLKKKHTQALDEN----NSIKHKYENLQQQFHKINVELVQSKAKELEFGEINRN 610
++ I +L+++ T+A EN + ++LQ++ N EL + E + +
Sbjct: 1053 FEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIAD 1112
Query: 611 LREQFEELESASNHTSNSFKRVNDKVHALEKEKSALN 647
L+ E ++ A+ + S + ++ + L+ EKS N
Sbjct: 1113 LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETN 1149
>Hs11321579 [Z] KOG0161 Myosin class II heavy chain
Length = 1938
Score = 52.0 bits (123), Expect = 3e-06
Identities = 81/464 (17%), Positives = 179/464 (38%), Gaps = 70/464 (15%)
Query: 184 LLEDQIKGLKHSKSENDSLIAELGDSYKLLNEKVKSSIAESEALKITXXXXXXXXXXXXX 243
LLE ++K L E + + +EL + L +K S + + L++T
Sbjct: 918 LLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATEN 977
Query: 244 XXXXXXXXXXXXXXXXXXCSGQLSEEKIKYTELLQQLSTSKKEITAEIQECFNKVEATSN 303
LSEE E + +L+ KK + Q+ + ++ +
Sbjct: 978 KVK------------------NLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEED 1019
Query: 304 TRVDTLQNYVNSRLQAICENIKEANVDIAKGLGMDLNQKTEKLISELGVVKDSVSTAATS 363
+V+ L +N++L+ +++ E +++ K L DL + KL +L + ++S+
Sbjct: 1020 -KVNGLIK-INAKLEQQTDDL-EGSLEQEKKLRADLERAKRKLEGDLKMSQESIMD---- 1072
Query: 364 TTEIIMHEVNKLYVTLPHIENIVSELKEMTANNGTLTMEFITSAFLSSVDTLLKTLQVSM 423
+ +E ++ L E +S+L+ + +++F +K LQ +
Sbjct: 1073 ----LENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQF---------QKKIKELQARI 1119
Query: 424 ESLQKLPDAICTLDNKITSAEG-FENEINALKEEVHTTMLQKTETVSMLRSKDHXXXXXX 482
E L++ +A TL KI E+ + E + + + M + ++
Sbjct: 1120 EELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQK-- 1177
Query: 483 XXXXXXXXXXXXXXDKNAILQTEFSSITVSNEAYVREITRIKKENEEAITSLDSKLTAQT 542
++ + T+ +EA ++K+ +++ L ++
Sbjct: 1178 -------------------MRRDLEEATLQHEATA---ATLRKKQADSVAELGEQIDNLQ 1215
Query: 543 EISSILQKDMNDTKKEIDSLKKKHTQALDENNSIKHKYENLQQQFHKINVELVQSKAKEL 602
+ L+K+ ++ K EID + ++I+ ++ QF +I KAK+
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI-------KAKDE 1268
Query: 603 EFGEINRNLREQFEELESASNHTSNSFKRVNDKVHALEKEKSAL 646
+ ++ +L Q L++ + S+ + + L K K AL
Sbjct: 1269 QQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQAL 1312
>CE00283 [O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation
Length = 834
Score = 51.2 bits (121), Expect = 6e-06
Identities = 89/440 (20%), Positives = 174/440 (39%), Gaps = 73/440 (16%)
Query: 263 SGQLSEEKIKYTELLQQLSTSKKEITAEIQECFNKVEATSNTRVDTLQNYVNSRLQAICE 322
+G E K L Q + E+T +C+N +E D L N R+Q +
Sbjct: 182 NGVHKELTAKAASLAIQNEKLQSEVTKVQSDCYN-LERKKRILTDKLSVQEN-RVQELEH 239
Query: 323 NIKEANVDIAKGLGM--DLNQKTEKLISEL------GVVKDSVSTAATSTTEIIMHEVNK 374
+++A + K + + K L+SE G S T + +I ++
Sbjct: 240 QLEDARFETDKHMRLANKFEYKLATLVSEGQSGGNGGATPSSSGTTNATEKKISAPDIPP 299
Query: 375 LYVTLPHIENIVSELKEMTANNGTLTMEFITSAFLSSVDTLLKTLQVSMESLQKL---PD 431
IEN+ E E E I S L ++ + K +Q + KL
Sbjct: 300 SETAAKEIENLRLERDEQ---------ESIASRRLQDLEEMNKKVQTLTQENSKLRLETQ 350
Query: 432 AICTLDNKITSAEGFEN----------EINALKEEVHTTMLQKT------ETVSMLRSKD 475
++D+ I ++E ++N E + +++ ++ E +ML S++
Sbjct: 351 TFFSVDS-IVNSEEYKNLKKYYSLAIKEYERVSKDLEDITTERDAFRSAKEARAMLMSEE 409
Query: 476 HXXXXXXXXXXXXXXXXXXXXDKNA-ILQTEFSSITVSNEAYVREITRIKKENEEAIT-- 532
H ++ +L+ EF ++ E Y + + + + + +A
Sbjct: 410 HQKTLKEIQCQSDIHNSFYKVSHDSEVLRCEFETV---KEEYNKTVKQSEWDEMKATLNT 466
Query: 533 ------SLDSKLTAQTEISSILQKDMNDTKKEIDSLKKKHTQAL------------DENN 574
SL S+ E QKD+N K E+ SLK+ + L ++ N
Sbjct: 467 LRSMNRSLKSEKIRLREKDKQSQKDINTLKSELTSLKEAQDKCLLVPLEDVSNAPPEDVN 526
Query: 575 SIKHKYENLQQQFHKINVELVQSKAKELEFGEINRNLREQFEELES---ASNHTSNSFKR 631
I+ +YE+L ++ ++ Q K K++E E+NR + ++ ELE+ + +N +
Sbjct: 527 KIRQEYESLCKEVKRLGAMEKQEKQKQVE-KEVNRQIADKLSELETLRKTNEMLTNDEEC 585
Query: 632 VNDKVHAL------EKEKSA 645
++D++ A+ E+E++A
Sbjct: 586 ISDELEAIGTAVEEEQERNA 605
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.307 0.124 0.317
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,608,692
Number of Sequences: 60738
Number of extensions: 1170769
Number of successful extensions: 6221
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 6118
Number of HSP's gapped (non-prelim): 80
length of query: 755
length of database: 30,389,216
effective HSP length: 114
effective length of query: 641
effective length of database: 23,465,084
effective search space: 15041118844
effective search space used: 15041118844
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)