ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2673 good BK KOG2626 Chromatin structure and dynamics Histone H3 (Lys4) methyltransferase complex, subunit CPS60/ASH2/BRE2
r_klactIII2673 good BK KOG2626 Transcription Histone H3 (Lys4) methyltransferase complex, subunit CPS60/ASH2/BRE2
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2673 941764 942978 405
(405 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR015w [BK] KOG2626 Histone H3 (Lys4) methyltransferase complex... 372 e-103
SPBC13G1.08c [BK] KOG2626 Histone H3 (Lys4) methyltransferase co... 124 2e-28
At1g51450 [BK] KOG2626 Histone H3 (Lys4) methyltransferase compl... 52 1e-06
>YLR015w [BK] KOG2626 Histone H3 (Lys4) methyltransferase complex subunit
CPS60/ASH2/BRE2
Length = 505
Score = 372 bits (955), Expect = e-103
Identities = 220/499 (44%), Positives = 296/499 (59%), Gaps = 95/499 (19%)
Query: 1 MSVPVIPYLD-YDIVDLGS-----DIKKPDFPQLSESHRINEQ------QYYITEDTPLN 48
M + +IPY + DIV + + K+P+ PQ+ +H+I ++ TED PLN
Sbjct: 1 MKLGIIPYQEGTDIVYKNALQGQQEGKRPNLPQMEATHQIKSSVQGTSYEFVRTEDIPLN 60
Query: 49 KRNFMYQPCAANLMLDKLKYCGTDY-FDKSSINLMDRSDKLAFSLDDHS-VSVSENCGWR 106
+R+F+Y+PC+AN L Y T+Y FD S +++MDRS+ L+ S D + VSV + GWR
Sbjct: 61 RRHFVYRPCSANPFFTILGYGCTEYPFDHSGMSVMDRSEGLSISRDGNDLVSVPDQYGWR 120
Query: 107 SVRSDVCMKEGKIYWEVEV----------------------------------KNVSDTS 132
+ RSDVC+KEG YWEVEV K V+DT
Sbjct: 121 TARSDVCIKEGMTYWEVEVIRGGNKKFADGVNNKENADDSVDEVQSGIYEKMHKQVNDTP 180
Query: 133 HIRCGISRREASTETPVGCDFYGYSIRDKGLQVIHEGRLHTVLKPHE-MQAGDRIGFLLT 191
H+R G+ RREAS E PVG D YGY IRD L+ IHEG+L+ VL+ ++ GD+IGFLL+
Sbjct: 181 HLRFGVCRREASLEAPVGFDVYGYGIRDISLESIHEGKLNCVLENGSPLKEGDKIGFLLS 240
Query: 192 LPSLQSQSEQAMDYSLKRIQELN---------------NDDSRTNKRNKKFNKEFYKFLL 236
LPS+ +Q +QA +++ +RI LN N SR + + NKEF + LL
Sbjct: 241 LPSIHTQIKQAKEFTKRRIFALNSHMDTMNEPWREDAENGPSRKKLKQETTNKEFQRALL 300
Query: 237 RSCEPTNVVRDQIAIRYKNQLFYESTDYVKTTKPEYY-DNRDDMQKFYELENSSFEVFVN 295
E +VVRDQIAIRYKNQLF+E+TDYVKTTKPEYY ++ + Q +Y+LE+S +F N
Sbjct: 301 EDIEYNDVVRDQIAIRYKNQLFFEATDYVKTTKPEYYSSDKRERQDYYQLEDSYLAIFQN 360
Query: 296 GVSHGIAFEGLTPFLPPFSELQYNEKFYLHHW---------NKRNVT------------K 334
G G AFE L P LPPFSELQYNEKFYL +W N +N T K
Sbjct: 361 GKYLGKAFENLKPLLPPFSELQYNEKFYLGYWQHGEARDESNDKNTTSAKKKKQQQKKKK 420
Query: 335 GIEIRNKYVNNNRLGYYATLSSFQGGTASIITEAMELKFLPK---------DVDIKTLND 385
G+ +RNKYVNNN+LGYY T+S F GGTA II+E +L++L + + + TL+
Sbjct: 421 GLILRNKYVNNNKLGYYPTISCFNGGTARIISEEDKLEYLDQIRSAYCVDGNSKVNTLDT 480
Query: 386 IYNEQIASDIVWDLIDEID 404
+Y EQIA DIVWD+IDE++
Sbjct: 481 LYKEQIAEDIVWDIIDELE 499
>SPBC13G1.08c [BK] KOG2626 Histone H3 (Lys4) methyltransferase complex subunit
CPS60/ASH2/BRE2
Length = 652
Score = 124 bits (311), Expect = 2e-28
Identities = 103/373 (27%), Positives = 159/373 (42%), Gaps = 71/373 (19%)
Query: 39 YYITEDTPLNKRNFMYQPCAANLMLDKLKYCGTDYFDKSS-INLMDRSDKLAFSLDDHSV 97
++ + P N+R F Y PC A L + Y + +S IN D S + +D ++
Sbjct: 311 FFSLSEIPFNRRGFRYSPCEAAKDLPNVMYREIELPPFTSRINWHDISTPVF--IDHSAL 368
Query: 98 SVSENCGWRSVRSDVCMKEGKIYWEVEVKNVS--DTSHIRCGISRREASTETPVGCDFYG 155
+ G+R RS+V M G+ Y+E++++ D +H+R G+SRREA + PVG D Y
Sbjct: 369 CATVEKGFRMARSNVFMTSGEWYFEIKIEKGGGDDGAHVRIGVSRREAPLDAPVGYDAYS 428
Query: 156 YSIRDKGLQVIHEGRLHTVLKPHEMQAGDRIGFLLTLPSLQSQSEQAMDYSLKRIQELNN 215
Y +RD G Q +H R + GD IG ++LP
Sbjct: 429 YGLRDLGGQKVHMSRPRNFM--DSFGTGDIIGLHISLPKPSFAQHTT------------- 473
Query: 216 DDSRTNKRNKKFNKEFYKFLLRSCEPTNVVRDQIAIRYKNQLFYESTDYVKTTKPEYYDN 275
L SC D+I IRYK QL++E DYV + +
Sbjct: 474 --------------------LPSC------HDRIPIRYKGQLYFEQPDYVPSKMMDELMI 507
Query: 276 RDDMQKFYEL---ENSSFEVFVNGVSHGIAFEGLTPFLPPFSELQYNEKFYLHHWNKRNV 332
++ +L S +V+ NG G AFE L F PP S
Sbjct: 508 PSKHNRYIDLPYIPGSFIKVYKNGSYMGTAFENLLDFNPPNS------------------ 549
Query: 333 TKGIEIRNKYVNNNRLGYYATLSSFQGGTASI-ITEAMELKFLPKDVDIKTLNDIYNEQI 391
I + ++ LGYY ++S + GG A + L +++ +++ YNEQI
Sbjct: 550 ---INSNHYSFDDGSLGYYPSISMYGGGIARFQFGPQFSHRPLVLGSNVRPVSERYNEQI 606
Query: 392 ASDIVWDLIDEID 404
A D++ D++DEID
Sbjct: 607 AEDVLCDILDEID 619
>At1g51450 [BK] KOG2626 Histone H3 (Lys4) methyltransferase complex subunit
CPS60/ASH2/BRE2
Length = 509
Score = 52.4 bits (124), Expect = 1e-06
Identities = 36/122 (29%), Positives = 60/122 (48%), Gaps = 3/122 (2%)
Query: 84 RSDKLAFSLDDHSVSVSENCGWRSVRSDVCMKEGKIYWEVEVKNVSDTSHIRCGISRREA 143
+++K+ S D + S+ G+R VR+ + EG Y+E++V ++ +T H R G S +
Sbjct: 280 KAEKVEISEDRLTAGSSK--GYRMVRATRGVVEGAWYFEIKVLSLGETGHTRLGWSTDKG 337
Query: 144 STETPVGCDFYGYSIRDKGLQVIHEGRLHTVLKPHEMQAGDRIGFLLTLPSLQSQSEQAM 203
+ PVG D + RD IH+ L + GD IGF + LP +S + +
Sbjct: 338 DLQAPVGYDGNSFGFRDIDGCKIHKA-LRETYAEEGYKEGDVIGFYINLPDGESFAPKPP 396
Query: 204 DY 205
Y
Sbjct: 397 HY 398
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,258,743
Number of Sequences: 60738
Number of extensions: 1119225
Number of successful extensions: 3004
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2987
Number of HSP's gapped (non-prelim): 5
length of query: 405
length of database: 30,389,216
effective HSP length: 109
effective length of query: 296
effective length of database: 23,768,774
effective search space: 7035557104
effective search space used: 7035557104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)