ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2691 good EO KOG1046 Amino acid transport and metabolism Puromycin-sensitive aminopeptidase and related aminopeptidases
r_klactIII2691 good EO KOG1046 Posttranslational modification, protein turnover, chaperones Puromycin-sensitive aminopeptidase and related aminopeptidases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2691 947926 950502 859
(859 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL157w [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 1247 0.0
YHR047c [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 1148 0.0
SPBC1921.05 [EO] KOG1046 Puromycin-sensitive aminopeptidase and ... 737 0.0
7292091 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 538 e-152
Hs15451907 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 494 e-139
CE10790 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 491 e-138
Hs4503575 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 443 e-124
Hs20534524 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 442 e-124
Hs20149637 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 403 e-112
Hs5031881 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 397 e-110
7299747 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 394 e-109
Hs4502095 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 389 e-107
7301772 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 384 e-106
7301751 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 379 e-104
7299744 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 377 e-104
Hs11641261 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 373 e-103
At4g33090 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 371 e-102
7301771 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 362 2e-99
Hs7019561 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 355 2e-97
CE21162 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 347 6e-95
ECU08g0070 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 343 5e-94
ECU01g1470 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 343 5e-94
ECU01g0140 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 343 5e-94
7299745 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 340 4e-93
Hs22064092 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 325 1e-88
7300769 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 318 2e-86
7301517 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 316 8e-86
7300768 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 293 1e-78
CE24087 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 288 2e-77
7301770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 284 5e-76
7300767 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 280 7e-75
CE20255 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 240 6e-63
CE26001 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 237 5e-62
CE18904 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 237 7e-62
7291179 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 227 5e-59
CE18905 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 225 3e-58
YIL137c [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 196 1e-49
7291558 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 192 2e-48
CE27507 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 184 7e-46
7291178 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 174 4e-43
7298258 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 166 1e-40
7300975 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 160 8e-39
CE05135 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 152 2e-36
7294697 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 126 1e-28
CE13593 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 116 2e-25
CE24840 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 115 3e-25
7298498 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 104 5e-22
At1g63770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and re... 100 1e-20
YNL045w [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 89 4e-17
CE28160 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/ami... 88 6e-17
Hs4505029 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/a... 84 9e-16
Hs13443031 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 79 4e-14
Hs20537652 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 76 3e-13
At5g13520 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/a... 70 1e-11
Hs17472410 [EO] KOG1046 Puromycin-sensitive aminopeptidase and r... 68 5e-11
SPCC1322.05c [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolas... 63 2e-09
CE25399 [EO] KOG1046 Puromycin-sensitive aminopeptidase and rela... 60 1e-08
Hs20070296 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 59 3e-08
CE19614 [K] KOG1932 TATA binding protein associated factor 55 4e-07
Hs21361893 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/... 54 8e-07
>YKL157w [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 935
Score = 1247 bits (3227), Expect = 0.0
Identities = 601/842 (71%), Positives = 702/842 (82%), Gaps = 2/842 (0%)
Query: 1 MSSQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIH 60
++ P+R ILP NV PLHY L +EP F TFKF+G+V I+LK+N+ D V LNT + DIH
Sbjct: 93 LNKTPNREILPDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIH 152
Query: 61 EAKINDVKSLETVTDEENQTSRFKFPAGTLKD-SDNVTIDIKFTGILNDTMAGFYRAKYI 119
AKI DV S E +++EE Q + F FP GT+ N +DIKFTGILND MAGFYRAKY
Sbjct: 153 SAKIGDVTSSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYE 212
Query: 120 DNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF 179
D TGETKYMATTQMEPTDARRAFPCFDEPNLKASF ITLVSDP LTHLSNMDVK E +
Sbjct: 213 DKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVK 272
Query: 180 DGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKT 239
DGKK T FN TPKMSTYLVAFIVAEL+YVE K+FRIPVRVYATPG+E GQ+AA+LTAKT
Sbjct: 273 DGKKVTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYATPGNEKHGQFAADLTAKT 332
Query: 240 LSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAE 299
L+FFEK FGI+YPLPKMD+VAVHEFSAGAMENWGLVTYRVVDLLLD+ N++L+RI+RVAE
Sbjct: 333 LAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAE 392
Query: 300 VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSAL 359
VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWY+CN+FQPEWKVWEQYV D LQ AL
Sbjct: 393 VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQHAL 452
Query: 360 GLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKF 419
LDSLRSSHPIEVPVK+ADEINQIFD ISY+KG+SLLRMIS+WLGE+ F+KGVSQYLNKF
Sbjct: 453 SLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKF 512
Query: 420 KFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGH-KITFKQNRYLNTAD 478
K+GNAKTEDLWDAL++ASGKDVR+VM+IWTKKVGFP++SV+EDG+ KITF+QNRYL+TAD
Sbjct: 513 KYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNGKITFRQNRYLSTAD 572
Query: 479 VKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTNANQAGIYVTSYSDD 538
VKP+EDKT+YPVFL+LKT +GVD S+ L ER T+ +ED F K N+ Q+GIY+TSY+D+
Sbjct: 573 VKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELEDPTFFKVNSEQSGIYITSYTDE 632
Query: 539 RWTTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINS 598
RW L +Q+DLL+VEDR GLVAD KTLS SGYTST NFL L+S+W NE SFVVW+Q+INS
Sbjct: 633 RWAKLGQQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKSFVVWDQIINS 692
Query: 599 LGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXX 658
+ S+K+ W FEPKET +ALD FT+QL+S TH LGWEF ++S+++QRLKV MF
Sbjct: 693 ISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQRLKVTMFGAACAA 752
Query: 659 XXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDE 718
MF Y SG+ AIP LIK VF TVAR G A+NYEK++ IY +P S+DE
Sbjct: 753 RDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYEKVYKIYLDPISNDE 812
Query: 719 KLSALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWD 778
KL+ALR LGRF++P L++RTLGYLFDGTVLNQDIYIPM GMR H+EG++ LW W K+NWD
Sbjct: 813 KLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMRAHQEGVEALWNWVKKNWD 872
Query: 779 ALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKA 838
L K+ PP L+MLGS++T+ TSGFTS Q IDEI+ FF KSTKGFDQSLAQ+LDTITSKA
Sbjct: 873 ELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKSTKGFDQSLAQSLDTITSKA 932
Query: 839 NW 840
W
Sbjct: 933 QW 934
>YHR047c [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 856
Score = 1148 bits (2970), Expect = 0.0
Identities = 550/852 (64%), Positives = 670/852 (78%), Gaps = 1/852 (0%)
Query: 7 RIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIND 66
R +LP NV+PLHY + LEP F F F+G++ IDL++ND + V++N E+D H A+I
Sbjct: 3 REVLPNNVTPLHYDITLEPNFRAFTFEGSLKIDLQINDHSINSVQINYLEIDFHSARIEG 62
Query: 67 VKSLETVTDEENQTSRFKFPAGTLKD-SDNVTIDIKFTGILNDTMAGFYRAKYIDNATGE 125
V ++E +E Q + FP GT ++ + ++I F+GILND MAGFYRAKY D TGE
Sbjct: 63 VNAIEVNKNENQQKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAKYTDKVTGE 122
Query: 126 TKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFT 185
TKYMATTQME TDARRAFPCFDEPNLKA+F +TLVS+ LTHLSNMDV+ E I +GKK+T
Sbjct: 123 TKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGKKYT 182
Query: 186 YFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSFFEK 245
FN TPKMSTYLVAFIVA+L YVE +FRIPVRVY+TPG E GQ+AANL A+TL FFE
Sbjct: 183 TFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLRFFED 242
Query: 246 AFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHEL 305
F IEYPLPKMD VAVHEFSAGAMENWGLVTYRV+DLLLD +N+SL+RI+RVAEV+QHEL
Sbjct: 243 TFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHEL 302
Query: 306 AHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGLDSLR 365
AHQWFGNLVTMDWWEGLWLNEGFATWMSWY+CN+FQPEWKVWEQYV D+LQ AL LDSLR
Sbjct: 303 AHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLR 362
Query: 366 SSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFGNAK 425
SSHPIEVPV ADEINQIFD ISY+KGSSLLRMIS+WLGE+ F+KGVSQYLNKFK+GNAK
Sbjct: 363 SSHPIEVPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAK 422
Query: 426 TEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGHKITFKQNRYLNTADVKPEEDK 485
T DLWDAL++ASGKDV +VM+IWTK+VGFP++SV E +KIT Q+RYL+T DVK EED
Sbjct: 423 TGDLWDALADASGKDVCSVMNIWTKRVGFPVLSVKEHKNKITLTQHRYLSTGDVKEEEDT 482
Query: 486 TLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSK 545
T+YP+ L+LK ++G+D++L L+E+ T +++ +F K N +Q+GI++TSYSD+RW LSK
Sbjct: 483 TIYPILLALKDSTGIDNTLVLNEKSATFELKNEEFFKINGDQSGIFITSYSDERWAKLSK 542
Query: 546 QSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAA 605
Q++LL+VEDR GLVAD K LS SGYTST NFL LIS WKNEDSFVVWEQ+INSL +LK+
Sbjct: 543 QANLLSVEDRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKST 602
Query: 606 WAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXX 665
W FEP++ L ALD+FT LV K LGW E++S+A QRLKV +F
Sbjct: 603 WVFEPEDILNALDKFTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQS 662
Query: 666 XXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRC 725
MFE+Y +G+ AIP L K+ VF TVAR G NYEK+F IY+NP SS+EK+ ALR
Sbjct: 663 IAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRA 722
Query: 726 LGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFP 785
LGRFED L++RTL YL DGTVLNQD YIPM G+R HK+GI+ LWAW +E+WD + K+
Sbjct: 723 LGRFEDKELLERTLSYLLDGTVLNQDFYIPMQGIRVHKKGIERLWAWMQEHWDEIAKRLQ 782
Query: 786 PSLTMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKANWVDRDR 845
P +LG +LT+ + FTS +A+++I F+ K TKGFDQ+LAQ LDTI SKA WV RDR
Sbjct: 783 PGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTKGFDQTLAQALDTIRSKAQWVSRDR 842
Query: 846 EVVVKFLKEHNY 857
E+V +L+EH Y
Sbjct: 843 EIVATYLREHEY 854
>SPBC1921.05 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 882
Score = 737 bits (1902), Expect = 0.0
Identities = 391/873 (44%), Positives = 555/873 (62%), Gaps = 28/873 (3%)
Query: 6 DRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN 65
+R +LP+NV P+HY L L P +TF + G V + L V + +S+ + L+ L I A +
Sbjct: 16 NRNLLPKNVKPIHYDLSLYPDLETFTYGGKVVVTLDVLE-DSNSITLHGINLRILTAALE 74
Query: 66 DVKSLETVTDEENQTSRF--KFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNAT 123
++ R +FP+ T+ + + + FT ++ M GFYR+ Y+D+
Sbjct: 75 WGSQTVWASEVSYGDERIVLQFPS-TVPANSVAVLTLPFTARISSGMEGFYRSSYVDS-D 132
Query: 124 GETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKK 183
G TKY+ATTQMEPT ARRAFPC+DEP LKA+F I + + T LSNM+ +E + DG K
Sbjct: 133 GNTKYLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNMNAVEETVKDGLK 192
Query: 184 FTYFNPTPKMSTYLVAFIVAELEYVE-------CKDFRIPVRVYATPGSEHLGQYAANLT 236
F T +MSTYL+A+IVAELEYVE C R+PVRVY TPG G++AA L
Sbjct: 193 TARFAETCRMSTYLLAWIVAELEYVEYFTPGKHCP--RLPVRVYTTPGFSEQGKFAAELG 250
Query: 237 AKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKR 296
AKTL FF FG YPLPK D VA+ +F AGAMENWGLVTYR+ +L+ E +A+ I+R
Sbjct: 251 AKTLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILVSEDSAATV-IER 309
Query: 297 VAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQ 356
VAEVVQHELAHQWFGNLVTM +W+GLWLNEGFATWMSW++CN F PEWKVWE YV D+LQ
Sbjct: 310 VAEVVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNHFYPEWKVWESYVTDNLQ 369
Query: 357 SALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYL 416
SAL LD+LRSSHPIEVP+ EINQIFD ISY+KGS ++RM+S+++GED F+KG+ +Y+
Sbjct: 370 SALSLDALRSSHPIEVPIMHDYEINQIFDAISYSKGSCVIRMVSKYVGEDTFIKGIQKYI 429
Query: 417 NKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTE--DGHKITFKQNRYL 474
+K ++GN TEDLW ALS SG+D+ + M WTKK G+P++SV+E DG ++ +Q+R+L
Sbjct: 430 SKHRYGNTVTEDLWAALSAESGQDISSTMHNWTKKTGYPVLSVSETNDG-ELLIEQHRFL 488
Query: 475 NTADVKPEEDKTLYPVFLSLKT----NSGVDHSLTLDER--ELTVTVEDVDFIKTNANQA 528
+T DVKPEED +Y L LKT + VD L +R ++ V E ++ K N+ Q+
Sbjct: 489 STGDVKPEEDTVIYWAPLKLKTMKDGKAVVDEKAVLSDRSKKIKVDKEALESYKLNSEQS 548
Query: 529 GIYVTSYSDDRWTTLS----KQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWK 584
GIY +YS D LS ++ D L+VEDR GL+AD +LS +GY + L LI WK
Sbjct: 549 GIYRVNYSADHLKKLSQIAVEKPDYLSVEDRAGLIADVASLSRAGYGKVSSTLDLIKTWK 608
Query: 585 NEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYAS 644
+E +FVV+ +M+ L +K+ FE + + A+ + ++ + K HSLGWEF N+ +
Sbjct: 609 DEPNFVVFAEMLARLNGIKSTLRFESSDIIAAMKKLVLEVSATKAHSLGWEFKANDDHII 668
Query: 645 QRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYE 704
++ K ++ F+ Y SG+ +AI ++S+VF R G AK+++
Sbjct: 669 RQFKSTVYNYAGLFGDDKVVKDALSKFDAYASGNKSAINDNLRSAVFNIAIRYGGAKSWD 728
Query: 705 KLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMRGHKE 764
+L IY + + S LR G ED +++TL D V QDIY+ + + HK
Sbjct: 729 QLLEIYTKTNDPYVRNSCLRAFGVTEDEKYIQKTLDLTLDPIVKEQDIYLILVTLSTHKN 788
Query: 765 GIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFD 824
G+ +W + NWD L + P + TM G ++ TSGFT AID+I++FF DK TK ++
Sbjct: 789 GVLAMWKFATSNWDKLLSRLPVAGTMRGYVVRFVTSGFTHASAIDKIKEFFADKDTKLYE 848
Query: 825 QSLAQTLDTITSKANWVDRDREVVVKFLKEHNY 857
++L Q+LDTI++ ++++D+ + + ++LKE+ Y
Sbjct: 849 RALQQSLDTISANSSFIDKSLDDITRWLKENRY 881
>7292091 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 866
Score = 538 bits (1387), Expect = e-152
Identities = 311/865 (35%), Positives = 478/865 (54%), Gaps = 30/865 (3%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN---- 65
LP NV P HY+L L+P F F G + + V + + + LN ++ + +++
Sbjct: 10 LPTNVVPRHYELLLQPNLKEFTFTGKTVVQVNVKEPTTQ-ITLNALDIVLDSVELHFECS 68
Query: 66 DVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGE 125
+K + V EN+T+ +F ++ V + + FTG LND M GFYR+KY GE
Sbjct: 69 KLKPEKIVYSAENETATLEFAQEIPAETQGV-LHMSFTGELNDKMKGFYRSKYF-GPNGE 126
Query: 126 TKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF-DGKKF 184
++ TQ E TDARR FPC+DEP +KA+F+ITLV LSNM V KE+ DG +
Sbjct: 127 ERFAGVTQFEATDARRCFPCWDEPAIKATFDITLVVPKDRVALSNMPVIKEDSLPDGLRR 186
Query: 185 TYFNPTPKMSTYLVAFIVAELEYVECK-DFRIPVRVYATPGSEHLGQYAANLTAKTLSFF 243
F+ TP MSTYLVA +V E +YVE K D + VRV+ G G +A + K L ++
Sbjct: 187 VRFDRTPIMSTYLVAVVVGEYDYVEGKSDDGVLVRVFTPVGKREQGTFALEVATKVLPYY 246
Query: 244 EKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQH 303
+ F I YPLPKMD +A+ +FSAGAMENWGLVTYR +L+D KN SL R + +A V H
Sbjct: 247 KDYFNIAYPLPKMDLIAISDFSAGAMENWGLVTYRETFVLVDPKNTSLMRKQSIALTVGH 306
Query: 304 ELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGLDS 363
E+AHQWFGNLVTM+WW LWLNEG+A+++ + + PE+ +W Q+V D AL LDS
Sbjct: 307 EIAHQWFGNLVTMEWWTHLWLNEGYASFVEFLCVHHLFPEYDIWTQFVTDMYTRALELDS 366
Query: 364 LRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFGN 423
L++SHPIEVPV EI++IFD ISY KG+S++RM+ ++GED F KG++ YL + ++GN
Sbjct: 367 LKNSHPIEVPVGHPSEIDEIFDEISYNKGASVIRMLHDYIGEDTFRKGMNLYLTRHQYGN 426
Query: 424 AKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGHKITFKQNRYLN------TA 477
TEDLW AL EAS K+V +VM WT+ GFP+VSV + T K R L TA
Sbjct: 427 TCTEDLWAALQEASSKNVSDVMTSWTQHKGFPVVSVESEQ---TSKNQRLLRLKQCKFTA 483
Query: 478 DVKPEEDKTLYPVFLSLKTN---SGVDHSLTLDERELTVTVEDV---DFIKTNANQAGIY 531
D ++ L+ V +S+ T+ +G+ + LD+ + VT+++V D+IK N G Y
Sbjct: 484 DGSQADENCLWVVPISVSTSKNPTGIAKTFLLDKSSMEVTLDNVDEDDWIKINPGTVGYY 543
Query: 532 VTSYSDDRWTTLSKQSDLLTVE--DRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSF 589
T YS + L + + + DR GL+ D + +G+ ST + L L+ ++NE ++
Sbjct: 544 RTRYSQEMLEQLMPAVEKMELPPLDRLGLIDDMFAMVQAGHASTADVLALVDSYRNETNY 603
Query: 590 VVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYASQRLKV 649
VW + NSL +L + +E F R L + LGWE + E++ L+
Sbjct: 604 TVWTAITNSLTNLHI--LISHTDLMEDFHRFGRNLYEPVAYRLGWEPRDGENHLDTLLRS 661
Query: 650 EMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAI 709
+ F ++ +G + +P ++++ + V +DG+ K + ++ +
Sbjct: 662 LVLTRLVSFRSSDTIEEAKIRFRRHVNG-TELLPADLRTTCYKAVLQDGDEKIFNEMLDL 720
Query: 710 YKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMRGHKEGIKTL 769
Y+ +E+ R LG D L++R + + V QD + + + +G
Sbjct: 721 YRATDLHEEQDRISRALGCCGDLKLLRRVIDFAMSSEVRAQDSVFVIVAVAINPKGRDMA 780
Query: 770 WAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQ 829
W + KEN L +++ +L ++ F S + E+E+F + G +++++Q
Sbjct: 781 WEFFKENNKQLLERYQGGF-LLSRLIKYLIENFASEERAKEVEEFLQVNQIPGCERTVSQ 839
Query: 830 TLDTITSKANWVDRDREVVVKFLKE 854
++TI A W+ RDRE + FL++
Sbjct: 840 AVETIRLNAAWLQRDREQLAIFLRD 864
>Hs15451907 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 875
Score = 494 bits (1271), Expect = e-139
Identities = 296/862 (34%), Positives = 462/862 (53%), Gaps = 25/862 (2%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKI---ND 66
LP +VSP++Y L L+P F F+G + +V + V +N ++DI A D
Sbjct: 10 LPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIV-MNCADIDIITASYAPEGD 68
Query: 67 VKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGET 126
+ T + +N+ + + + T+ I F G LND M GFYR+KY +GE
Sbjct: 69 EEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYT-TPSGEV 127
Query: 127 KYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTY 186
+Y A TQ E TDARRAFPC+DEP +KA+F+I+LV LSNM+V + + +
Sbjct: 128 RYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLV 187
Query: 187 ---FNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGSEHLGQYAANLTAKTLSF 242
F TP MSTYLVAF+V E ++VE + + VRVY G G++A + AKTL F
Sbjct: 188 EVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPF 247
Query: 243 FEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQ 302
++ F + YPLPK+D +A+ +F+AGAMENWGLVTYR LL+D KN+ + VA VV
Sbjct: 248 YKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVG 307
Query: 303 HELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGLD 362
HELAHQWFGNLVTM+WW LWLNEGFA+W+ + + PE+ +W Q+V+ D A LD
Sbjct: 308 HELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELD 367
Query: 363 SLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFG 422
+L +SHPIEV V E+++IFD ISY+KG+S++RM+ ++G+ F KG++ YL KF+
Sbjct: 368 ALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQK 427
Query: 423 NAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSV----TEDGHKITFKQNRYLNTAD 478
NA TEDLW++L ASGK + VM+ WTK++GFP++ V ED + Q ++
Sbjct: 428 NAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVEDDRLLRLSQKKFCAGGS 487
Query: 479 VKPEE-DKTLYPVFLSLKTN-SGVDHSLTLDERELTVTVEDV---DFIKTNANQAGIYVT 533
E+ + + P+ +S + + + +D+ E+ V +++V ++K N G Y T
Sbjct: 488 YVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRT 547
Query: 534 SYSDDRWTTLSKQ-SDL-LTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVV 591
YS +L DL L DR GL D +L+ +G ST L+++ + NE ++ V
Sbjct: 548 QYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTV 607
Query: 592 WEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEM 651
W + +LG L + E + EF + + S LGW+ E + L+ +
Sbjct: 608 WSDLSCNLGILST--LLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLV 665
Query: 652 FXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYK 711
F+ + G + ++S V+ TV + G+ + + ++K
Sbjct: 666 LGKLGKAGHKATLEEARRRFKDHVEG-KQILSADLRSPVYLTVLKHGDGTTLDIMLKLHK 724
Query: 712 NPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMR-GHKEGIKTLW 770
+EK R LG P L+++ L + V QD +GG+ G K G K W
Sbjct: 725 QADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAW 784
Query: 771 AWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQT 830
+ K+NW+ L+ ++ ++ ++ ++ GF + E++ FF+ ++++ Q
Sbjct: 785 KFIKDNWEELYNRYQGGF-LISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQC 843
Query: 831 LDTITSKANWVDRDREVVVKFL 852
+ I A W+ RD E + ++L
Sbjct: 844 CENILLNAAWLKRDAESIHQYL 865
>CE10790 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 884
Score = 491 bits (1264), Expect = e-138
Identities = 302/874 (34%), Positives = 474/874 (53%), Gaps = 33/874 (3%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKI----- 64
LP P HY ++L P + F FDG +ID+ + + +D ++++ L I +
Sbjct: 16 LPTFAEPTHYNVRLSPCLNQFSFDGHATIDVTIKEA-TDVLKVHAQSLLIQSVSLITQPG 74
Query: 65 NDVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATG 124
+ KSLET D++ K P T V +D KF G LND M GFYR++Y D G
Sbjct: 75 DASKSLETSYDDKLNILTIKLP--TTMQPQKVQLDFKFVGELNDKMRGFYRSQYKDK-NG 131
Query: 125 ETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEE-IFDGK- 182
K++A+TQ E T AR AFPCFDEP KA+F++TL + LT LSNM+V E DGK
Sbjct: 132 TEKFLASTQFESTYARYAFPCFDEPIYKATFDVTLEVENHLTALSNMNVISETPTADGKR 191
Query: 183 KFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGSEHLGQYAANLTAKTLS 241
K F +PKMS+YLVAF V ELEY+ + + +RVY PG + GQY+ +L+ K +
Sbjct: 192 KAVTFATSPKMSSYLVAFAVGELEYISAQTKSGVEMRVYTVPGKKEQGQYSLDLSVKCID 251
Query: 242 FFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVV 301
++ + F I+YPLPK D +A+ +FS GAMENWGLVTYR + LL+D S + RVA VV
Sbjct: 252 WYNEWFDIKYPLPKCDLIAIPDFSMGAMENWGLVTYREIALLVDPGVTSTRQKSRVALVV 311
Query: 302 QHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGL 361
HELAH WFGNLVTM WW LWL EGFA++M + PE+K+W ++ D+L S +GL
Sbjct: 312 AHELAHLWFGNLVTMKWWTDLWLKEGFASFMEYMFVGANCPEFKIWLHFLNDELASGMGL 371
Query: 362 DSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKF 421
D+LR+SHPIEV + +E+++I+D I+YAK +S+ RM+ +L E VF KG+ YL +F++
Sbjct: 372 DALRNSHPIEVEIDNPNELDEIYDSITYAKSNSVNRMLCYYLSEPVFQKGLRLYLKRFQY 431
Query: 422 GNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVT--EDGHK--ITFKQNRYLNTA 477
NA T+DLW ALSEASG++V +M WT+++GFP++ V+ +DG+ +T +Q R+++
Sbjct: 432 SNAVTQDLWTALSEASGQNVNELMSGWTQQMGFPVLKVSQRQDGNNRILTVEQRRFISDG 491
Query: 478 DVKPEEDKTLYPVFLSLKTN-SGVDHSLTLDERELTVTVEDV---DFIKTNANQAGIYVT 533
P+ + P+ +++ ++ S V L E++ T+E V +++K N+ G Y
Sbjct: 492 GEDPKNSQWQVPITVAVGSSPSDVKARFLLKEKQQEFTIEGVAPGEWVKLNSGTTGFYRV 551
Query: 534 SYSDDRWTTLSKQ--SDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVV 591
YSD+ T + S + V DR GL+ D L +G S F+Q+ + ED +VV
Sbjct: 552 EYSDEMLTAMLPDIASRRMPVLDRFGLINDLSALLNTGRVSIAQFVQVAASSAKEDEYVV 611
Query: 592 WEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEM 651
W + + L A ++TL++ + ++ + LG+ E L+ +
Sbjct: 612 WGAIDEGMSKLLACAREMSEDTLKSAKQLVVKMFEQTGAELGFAEQAGEDSQKMMLRSLV 671
Query: 652 FXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYK 711
MF + I P I+ + FG VAR G + ++KL + +
Sbjct: 672 QARLARAGHQPTIDKFTQMFNDFLE-KGTPIHPDIRLATFGVVARYGGKEGFDKLMNLRE 730
Query: 712 NPSSSDEKLSALRCLGRFEDPALMKRTLGYLFD-GTVLNQD-IYIPMGGMRGHKEGIKTL 769
+ + + + + + + +L+ + Y F+ V QD +Y+ +G H G +
Sbjct: 731 TTTFQEIERQTMVAMSQTPEESLLAQLFEYGFEKNKVRPQDQLYLFLGTGATHM-GQQYA 789
Query: 770 WAWTKEN-WDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFF------KDKSTKG 822
W + E+ + L K + ++ L A F + + E +DFF D +
Sbjct: 790 WKYFCEHIKEFLDKYGGANSSLFQRCLKFAGESFGNEKRAVEFQDFFCNCNVLSDTDRQT 849
Query: 823 FDQSLAQTLDTITSKANWVDRDREVVVKFLKEHN 856
+ + QT++ I A ++ +R+++ LK+ N
Sbjct: 850 LARPIGQTVEAIRLNARLLESNRQIIENLLKQSN 883
>Hs4503575 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 957
Score = 443 bits (1140), Expect = e-124
Identities = 282/878 (32%), Positives = 451/878 (51%), Gaps = 47/878 (5%)
Query: 2 SSQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHE 61
S Q LP V+P+HY L ++P + + GTVSI + ++ L + E
Sbjct: 85 SGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLS------APTRYLWLHLRE 138
Query: 62 AKINDVKSLETVTDEENQTSR-FKFPAG-----------TLKDSDNV-TIDIKFTGILND 108
+I + L+ + ++ Q R F++ T D + + ++F G LN
Sbjct: 139 TRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNG 198
Query: 109 TMAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHL 168
++ GFYR Y +N G K +A T EPTDAR++FPCFDEPN KA++ I++ + L
Sbjct: 199 SLVGFYRTTYTEN--GRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGAL 256
Query: 169 SNMDVKKEEIFDGK-KFTYFNPTPKMSTYLVAFIVAELEYVE-CKDFRIPVRVYATPGSE 226
SNM V KEE D K T F + MSTYLV F V + + V+ + P+ +Y P +
Sbjct: 257 SNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQK 316
Query: 227 HLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDE 286
H +YAAN+T +FE+ F + Y LPK+D +A+ +F GAMENWGL+TYR +LL D
Sbjct: 317 HTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDP 376
Query: 287 KNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKV 346
K ++ +RVA VV HEL HQWFGN+VTMDWWE LWLNEGFA++ + N + +W++
Sbjct: 377 KESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQM 436
Query: 347 WEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGED 406
+Q + +D+ DSL SSHPI V V DEI +FD ISY+KGSS+LRM+ W+ +
Sbjct: 437 RDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPE 496
Query: 407 VFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGHKI 466
F KG YL K++F NAKT D W AL EAS V+ VMD WT+++G+P+++V +G K
Sbjct: 497 NFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNV--NGVK- 553
Query: 467 TFKQNRYLNTADVKPEEDKT--LYPVFLSLK-TNSGVDHSLTLDERELT-VTVEDVD--- 519
Q R+L P + + Y + +K T + S+ + E +T+ +
Sbjct: 554 NITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSG 613
Query: 520 --FIKTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVADCKTLSLSGYTST 573
F+K N + G Y +Y W T LS + DR L+ D L+ +
Sbjct: 614 NAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDY 673
Query: 574 KNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLG 633
K L L K E++F+ W+++I+++ + + + + KE ++E+ + V SLG
Sbjct: 674 KVALNLTKYLKREENFLPWQRVISAVTYIISMFE-DDKELYPMIEEYFQGQVKPIADSLG 732
Query: 634 WEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFG- 692
W ++ + ++ L+ + +FE++ +G + ++P ++ V+
Sbjct: 733 W--NDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNG-TVSLPVNLRLLVYRY 789
Query: 693 TVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGTVL-NQD 751
+ GN ++ Y+ S + EK L L ++ L+ R L L D ++ QD
Sbjct: 790 GMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQD 849
Query: 752 IYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEI 811
++ + + + G W W + NWD L ++ + LG I+T+A F + + ++
Sbjct: 850 VFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIA-EPFNTELQLWQM 908
Query: 812 EDFFKDKSTKGF-DQSLAQTLDTITSKANWVDRDREVV 848
E FF G ++ Q L+T+ + W+ + R +
Sbjct: 909 ESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTI 946
>Hs20534524 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 957
Score = 442 bits (1138), Expect = e-124
Identities = 281/878 (32%), Positives = 451/878 (51%), Gaps = 47/878 (5%)
Query: 2 SSQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHE 61
S Q LP V+P+HY L ++P + + GTVSI + ++ L + E
Sbjct: 85 SGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLS------APTRYLWLHLRE 138
Query: 62 AKINDVKSLETVTDEENQTSR-FKFPAG-----------TLKDSDNV-TIDIKFTGILND 108
+I + L+ + ++ Q R F++ T D + + ++F G LN
Sbjct: 139 TRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNG 198
Query: 109 TMAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHL 168
++ GFYR Y +N G+ K + T EPTDAR++FPCFDEPN KA++ I++ + L
Sbjct: 199 SLVGFYRTTYTEN--GQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGAL 256
Query: 169 SNMDVKKEEIFDGK-KFTYFNPTPKMSTYLVAFIVAELEYVE-CKDFRIPVRVYATPGSE 226
SNM V KEE D K T F + MSTYLV F V + + V+ + P+ +Y P +
Sbjct: 257 SNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQK 316
Query: 227 HLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDE 286
H +YAAN+T +FE+ F + Y LPK+D +A+ +F GAMENWGL+TYR +LL D
Sbjct: 317 HTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDP 376
Query: 287 KNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKV 346
K ++ +RVA VV HEL HQWFGN+VTMDWWE LWLNEGFA++ + N + +W++
Sbjct: 377 KESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQM 436
Query: 347 WEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGED 406
+Q + +D+ DSL SSHPI V V DEI +FD ISY+KGSS+LRM+ W+ +
Sbjct: 437 RDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPE 496
Query: 407 VFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGHKI 466
F KG YL K++F NAKT D W AL EAS V+ VMD WT+++G+P+++V +G K
Sbjct: 497 NFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNV--NGVK- 553
Query: 467 TFKQNRYLNTADVKPEEDKT--LYPVFLSLK-TNSGVDHSLTLDERELT-VTVEDVD--- 519
Q R+L P + + Y + +K T + S+ + E +T+ +
Sbjct: 554 NITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSG 613
Query: 520 --FIKTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVADCKTLSLSGYTST 573
F+K N + G Y +Y W T LS + DR L+ D L+ +
Sbjct: 614 NAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDY 673
Query: 574 KNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLG 633
K L L K E++F+ W+++I+++ + + + + KE ++E+ + V SLG
Sbjct: 674 KVALNLTKYLKREENFLPWQRVISAVTYIISMFE-DDKELYPMIEEYFQGQVKPIADSLG 732
Query: 634 WEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFG- 692
W ++ + ++ L+ + +FE++ +G + ++P ++ V+
Sbjct: 733 W--NDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNG-TVSLPVNLRLLVYRY 789
Query: 693 TVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGTVL-NQD 751
+ GN ++ Y+ S + EK L L ++ L+ R L L D ++ QD
Sbjct: 790 GMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQD 849
Query: 752 IYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEI 811
++ + + + G W W + NWD L ++ + LG I+T+A F + + ++
Sbjct: 850 VFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIA-EPFNTELQLWQM 908
Query: 812 EDFFKDKSTKGF-DQSLAQTLDTITSKANWVDRDREVV 848
E FF G ++ Q L+T+ + W+ + R +
Sbjct: 909 ESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTI 946
>Hs20149637 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 948
Score = 403 bits (1036), Expect = e-112
Identities = 265/897 (29%), Positives = 432/897 (47%), Gaps = 61/897 (6%)
Query: 6 DRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN 65
++I LP+ V P+HY L + T F GT +++ + S + L++ L I A +
Sbjct: 50 NKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTII-LHSHHLQISRATLR 108
Query: 66 -------DVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKY 118
+ L+ + + P L T+ I + G L++T GFY++ Y
Sbjct: 109 KGAGERLSEEPLQVLEHPPQEQIALLAPEPLLVGLP-YTVVIHYAGNLSETFHGFYKSTY 167
Query: 119 IDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMD-VKKEE 177
GE + +A+TQ EPT AR AFPCFDEP KASF I + +P+ +SNM VK
Sbjct: 168 -RTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVT 226
Query: 178 IFDGKKFTYFNPTPKMSTYLVAFIVAELEYV-ECKDFRIPVRVYATPGSEHLGQYAANLT 236
+ +G +F+ T KMSTYLVAFI+++ E V + + V VYA P + YA +
Sbjct: 227 VAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAA 286
Query: 237 AKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKR 296
L F+E F I YPLPK D A+ +F +GAMENWGL TYR LL D + +S
Sbjct: 287 VTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLG 346
Query: 297 VAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQ 356
+ V HELAHQWFGNLVTM+WW LWLNEGFA +M + + + PE KV + Y
Sbjct: 347 ITVTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGD-YFFGKCF 405
Query: 357 SALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYL 416
A+ +D+L SSHP+ PV+ +I ++FD +SY KG+ +L M+ ++L D F G+ QYL
Sbjct: 406 DAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYL 465
Query: 417 NKFKFGNAKTEDLWDALS---------------------------EASGKDVRNVMDIWT 449
K + N K EDLWD+++ G DV+ +M+ WT
Sbjct: 466 QKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWT 525
Query: 450 KKVGFPIVSVTEDGHKITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDER 509
+ GFP++++T G + KQ Y+ +D P+ + + + S + H L +
Sbjct: 526 LQRGFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSNMVHRFLLKTK 585
Query: 510 -ELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLS----KQSDLLTVEDRTGLVADCKT 564
++ + E+V++IK N G Y+ Y DD W +L+ ++ DR L+ +
Sbjct: 586 TDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQ 645
Query: 565 LSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEA-----LDE 619
L G S + L L K+E + Q +N L + +E L
Sbjct: 646 LVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIR 705
Query: 620 FTRQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDS 679
R L+ ++T +++ S + Q L+ E+ F K+ +
Sbjct: 706 LLRDLIDKQT------WTDEGSVSEQMLRSELLLLACVHNYQPCVQRAEGYFRKWKESNG 759
Query: 680 N-AIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRT 738
N ++P + +VF A+ + + ++ L++ Y+ SS EK L R ++ ++
Sbjct: 760 NLSLPVDVTLAVFAVGAQ--STEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWL 817
Query: 739 LGYLFDGTVLNQDIYIPMGGMRGHKE-GIKTLWAWTKENWDALHKKFPPSLTMLGSILTV 797
L F G + + + + G G W + ++NW+ L +KF + + ++
Sbjct: 818 LDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMG 877
Query: 798 ATSGFTSRQAIDEIEDFFKDKSTKGFD-QSLAQTLDTITSKANWVDRDREVVVKFLK 853
T+ F++R ++E++ FF G + + QT++TI W+D++ + + +L+
Sbjct: 878 TTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQ 934
>Hs5031881 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1025
Score = 397 bits (1021), Expect = e-110
Identities = 276/877 (31%), Positives = 443/877 (50%), Gaps = 63/877 (7%)
Query: 7 RIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEA--KI 64
+I LP V PL Y+L L P + F G+V+I ++ T+ + +H I
Sbjct: 165 QIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQV--------TWNIILHSTGHNI 216
Query: 65 NDVKSLETVTDEENQTSRFKFP---------AGTLKDSDNVTIDIKFTGILNDTMAGFYR 115
+ V + V+ +E Q ++ L N T+ I+++ ++ + GFY
Sbjct: 217 SRVTFMSAVSSQEKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYG 276
Query: 116 AKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKK 175
Y D + E KY A TQ EP AR AFPCFDEP KA+F I ++ D + T LSNM K
Sbjct: 277 FSYTDESN-EKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKS 335
Query: 176 EEIFD-GKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQ--YA 232
+ D G F+ + KMSTYLVAFIV E++ + V +YA P E++GQ YA
Sbjct: 336 SVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVP--ENIGQVHYA 393
Query: 233 ANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLE 292
T K L FF+ F I+YPL K+D VA+ +F AGAMENWGL+T+R LL D +S+
Sbjct: 394 LETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMA 453
Query: 293 RIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVA 352
K V +++ HELAHQWFGNLVTM WW LWLNEGFAT+M +++ + E +E ++
Sbjct: 454 DRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFL- 512
Query: 353 DDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGV 412
D + DSL SSHPI V+ +++I ++FD +SY KGSSLL M+ +L EDVF V
Sbjct: 513 DARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAV 572
Query: 413 SQYLNKFKFGNAKTEDLWDALSEASGK--DVRNVMDIWTKKVGFPIVSVTEDGHKITFKQ 470
YL+ + + +++DLWD+ +E + + DV+ +M WT + GFP+V+V + G ++ +Q
Sbjct: 573 VLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQ 632
Query: 471 NR-YLN-TADVKPEEDKTLYPVFLSLKT---NSGVDHSLTLDERELTV--TVEDVDFIKT 523
R +LN +++P + L+ + LS T N S++L +++ V E+V ++K
Sbjct: 633 ERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSKYQSVSLLDKKSGVINLTEEVLWVKV 692
Query: 524 NANQAGIYVTSYSDDRWTTLSKQSDL----LTVEDRTGLVADCKTLSLSGYTSTKNFLQL 579
N N G Y+ Y+DD W L Q + L+ +DR L+ + L+ G K L
Sbjct: 693 NINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLINNIFELAGLGKVPLKRAFDL 752
Query: 580 ISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTR------QLVSEKTHSLG 633
I+ NE+ + + + + E L +D +R +L+ +
Sbjct: 753 INYLGNENHTAPITEAL-----FQTDLIYNLLEKLGYMDLASRLVTRVFKLLQNQIQQQT 807
Query: 634 WEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKY-TSGDSNAIPPLIKSSVFG 692
W ++ + + + L+ + +F+ + S + ++P + ++VF
Sbjct: 808 W--TDEGTPSMRELRSALLEFACTHNLGNCSTTAMKLFDDWMASNGTQSLPTDVMTTVFK 865
Query: 693 TVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPA----LMKRTLGYLFDGTVL 748
A+ K + L Y + S EK L L ED LMK +L
Sbjct: 866 VGAK--TDKGWSFLLGKYISIGSEAEKNKILEALASSEDVRKLYWLMKSSLN---GDNFR 920
Query: 749 NQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAI 808
Q + + + H G W + KENW+ L +KFP + +I+ +T F+++ +
Sbjct: 921 TQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHL 980
Query: 809 DEIEDFFKDKSTKGFD-QSLAQTLDTITSKANWVDRD 844
E++ FF+++S F + + + L+ I W++++
Sbjct: 981 SEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKN 1017
>7299747 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 985
Score = 394 bits (1013), Expect = e-109
Identities = 244/780 (31%), Positives = 400/780 (51%), Gaps = 40/780 (5%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVND---------KESDFVELNTFELDIH 60
LP+ + P Y+L L P + + G +SI L+V + K+ + + LD
Sbjct: 144 LPKQIKPSKYRLHLRPDLERKNYSGNISISLQVLEPIAFIPVHVKQLNVSTVEVKRLDES 203
Query: 61 EAKINDVKSLETVTDEENQ--TSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKY 118
A + D+ T E + + F+ P ++ N ++ + FTG L D + G Y++ Y
Sbjct: 204 GAPLKDITPTLTFAHPEFEYWVTEFEQPL----EAGNYSLLLNFTGSLVDRITGMYQSSY 259
Query: 119 IDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLV--SDPKLTHLSNMDVKKE 176
+D ++ + +T+ EPT AR+AFPCFDEP LKA F IT+ S + LSNM V E
Sbjct: 260 LDKLKNRSRSIISTKFEPTYARQAFPCFDEPALKAQFTITVARPSGDEYHVLSNMPVASE 319
Query: 177 EIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVEC--KDFRIPVRVYATPGSEHLGQYAAN 234
+ F T MSTYL AF+V++ +Y E + I ++VYA P QYA +
Sbjct: 320 YVDGDITEVTFAETVPMSTYLAAFVVSDFQYKETTVEGTSIALKVYAPPAQVEKTQYALD 379
Query: 235 LTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERI 294
A ++++ F + Y LPK+D VA+ +F +GAMENWGLVT+R LL DE +S
Sbjct: 380 TAAGVMAYYINYFNVSYALPKLDLVAIPDFVSGAMENWGLVTFRETALLYDESTSSSVNK 439
Query: 295 KRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADD 354
+RVA VV HELAHQWFGNLVTM+WW LWLNEGFA+++ + Q PEW + Q+V ++
Sbjct: 440 QRVAIVVAHELAHQWFGNLVTMNWWNDLWLNEGFASFLEYKGVKQMHPEWDMDNQFVIEE 499
Query: 355 LQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQ 414
L L +D+ +SHPI ++ EI + FD I+Y+KG++L+RM+ +GE+ ++
Sbjct: 500 LHPVLTIDATLASHPIVKSIESPAEITEYFDTITYSKGAALVRMLENLVGEEKLRNATTR 559
Query: 415 YLNKFKFGNAKTEDLWDALSEASGK--DVRNVMDIWTKKVGFPIVSVTEDGHKITFKQNR 472
YL + + A TED A+ E G DV+ +M WT+++G P+V V + G Q R
Sbjct: 560 YLVRHIYSTATTEDYLTAVEEEEGLEFDVKQIMQTWTEQMGLPVVEVEKSGSTYKLTQKR 619
Query: 473 YL-NTADVKPEEDKTLY------PVFLSLKTNSGVDHSL-TLDERELTVTV-EDVDFIKT 523
+L N D E + + + P+ + NS V + ++ E T+T+ E+ +IK
Sbjct: 620 FLANEDDYAAEAEASSFNYRWSIPITYTSSINSEVQSLIFNHNDNEATITLPEEASWIKI 679
Query: 524 NANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQL 579
N NQ G Y +Y ++W + L + + DR L+ D TL+ +G + L L
Sbjct: 680 NTNQVGYYRVNYGSEQWAELISALKNSRETFSTADRAHLLNDANTLAAAGQLNYSVALDL 739
Query: 580 ISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSEN 639
IS ++E +V W ++L +L+ + T + R+L++ + F+
Sbjct: 740 ISYLESEQDYVPWSVGTSALATLRNRVYYTDLYT--NYTTYARKLLTPIVEKV--TFTVA 795
Query: 640 ESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGN 699
+ RL++++ +F ++ + P I+ V+ + N
Sbjct: 796 ADHLENRLRIKVLSSACSLGHESSLQQAVTLFNQWLASPETRPNPDIRDVVYYYGLQQVN 855
Query: 700 AK-NYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFD-GTVLNQDIYIPMG 757
+ +++++ +Y + S + EKL + CL + P L++R + + +D V QD + +G
Sbjct: 856 TEAAWDQVWKLYLDESDAQEKLKLMNCLTAVQVPWLLQRYINWAWDESNVRRQDYFTLLG 915
>Hs4502095 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 967
Score = 389 bits (999), Expect = e-107
Identities = 267/909 (29%), Positives = 442/909 (48%), Gaps = 72/909 (7%)
Query: 6 DRIILPQNVSPLHYKLQLEPYFD-------TFKFDGTVSIDLKVNDKESDFVELNTFELD 58
+R LP + P Y++ L PY FK TV K + +D + +++ +L+
Sbjct: 72 NRYRLPNTLKPDSYQVTLRPYLTPNDRGLYVFKGSSTVRFTCK---EATDVIIIHSKKLN 128
Query: 59 I-----HEAKIN--------DVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGI 105
H + D+ E V E K G+L +D +F G
Sbjct: 129 YTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLK---GSLVKDSQYEMDSEFEGE 185
Query: 106 LNDTMAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKL 165
L D +AGFYR++Y++ K +ATTQM+ DAR++FPCFDEP +KA F ITL+ L
Sbjct: 186 LADDLAGFYRSEYMEGNV--RKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDL 243
Query: 166 THLSNMDVKKEEI----FDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVY 220
T LSNM K T F+ TPKMSTYL+AFIV+E +YVE + + +R++
Sbjct: 244 TALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIW 303
Query: 221 ATPGSEHLGQ--YAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYR 278
A P + G YA N+T L+FF + YPLPK D + + +F+AGAMENWGLVTYR
Sbjct: 304 ARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYR 363
Query: 279 VVDLLLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACN 338
LL D ++S +RV V+ HELAHQWFGNLVT++WW LWLNEGFA+++ + +
Sbjct: 364 ENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGAD 423
Query: 339 QFQPEWKVWEQYVADDLQSALGLDSLRSSHPIEVPVKRAD---EINQIFDHISYAKGSSL 395
+P W + + V +D+ + +D+L SSHP+ P + +I+++FD ISY+KG+S+
Sbjct: 424 YAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASV 483
Query: 396 LRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGK-------DVRNVMDIW 448
LRM+S +L EDVF +G++ YL+ F + N +LWD L EA VR++M+ W
Sbjct: 484 LRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRW 543
Query: 449 TKKVGFPIVSVTEDGHKITFKQNRYLNTAD---VKPEEDKTLYPV-FLSLKTNSGVDHSL 504
T ++GFP+++V D T Q +L D +P E ++ V S++
Sbjct: 544 TLQMGFPVITV--DTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYW 601
Query: 505 TLDERELT--VTVEDVDFIKTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGL 558
+D R + +++ N N G Y +Y ++ W T L + + V +R +
Sbjct: 602 LIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQI 661
Query: 559 VADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALD 618
+ D L+ + L E ++ WE ++SL K F+ E +
Sbjct: 662 INDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKL--MFDRSEVYGPMK 719
Query: 619 EFTRQLVSE-----KTHSLGW-EFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFE 672
+ ++ V+ + ++ W E EN Q +V +F+
Sbjct: 720 NYLKKQVTPLFIHFRNNTNNWREIPEN--LMDQYSEVNAISTACSNGVPECEEMVSGLFK 777
Query: 673 KYTSG-DSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFED 731
++ ++N I P ++S+V+ G + ++ + ++N + +E L ++
Sbjct: 778 QWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKE 837
Query: 732 PALMKRTLGYLFDGTVL-NQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTM 790
++ R L Y + ++ QD + + + G +W + + NW L +
Sbjct: 838 LWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFS 897
Query: 791 LGSILTVATSGFTSRQAIDEIEDFFKDKSTKGF---DQSLAQTLDTITSKANWVDRDREV 847
+++ T F++ + ++E F KD GF ++L Q L+ + WV ++EV
Sbjct: 898 FSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEV 957
Query: 848 VVKFLKEHN 856
V+++ E++
Sbjct: 958 VLQWFTENS 966
>7301772 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 932
Score = 384 bits (985), Expect = e-106
Identities = 267/893 (29%), Positives = 436/893 (47%), Gaps = 64/893 (7%)
Query: 10 LPQNVSPLHYKLQLEPYFDT---FKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN- 65
LP ++ P Y L++ + +F G+V I ++ + + V L++ L I E++I
Sbjct: 34 LPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKN-VTLHSKNLTIDESQITL 92
Query: 66 -----DVKSLETVTDEENQTSRFKFPAGTLKD---SDNVTIDIKFTGILNDTMAGFYRAK 117
+ K V+ S + T ++ + + + F LN + G+YR+
Sbjct: 93 RQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSS 152
Query: 118 YIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNM---DVK 174
Y D TK+++ TQ EP AR AFPCFDEP+ KA F +TL K T +SNM + K
Sbjct: 153 YKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETK 212
Query: 175 KEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIP----VRVYATPGSEHLGQ 230
E + F + MSTYLVA+ V + + K +P R +A P +
Sbjct: 213 PHETLADYIWCEFQESVPMSTYLVAYSVNDFSH---KPSTLPNSALFRTWARPNAIDQCD 269
Query: 231 YAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNAS 290
YAA K L ++E+ FGI++PLPK+D +AV +FSAGAMENWGLVTYR + LL ++S
Sbjct: 270 YAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSS 329
Query: 291 LERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQY 350
L +RVA VV HELAHQWFGNLVTM WW LWLNEGFAT+++ PEW+ EQ
Sbjct: 330 LADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQE 389
Query: 351 VADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVK 410
+L + D+L SSHPI P++ EI++ FD ISY KGS++LRM+ +LGE+ F
Sbjct: 390 SLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRS 449
Query: 411 GVSQYLNKFKFGNAKTEDLWDALSEASGK--------DVRNVMDIWTKKVGFPIVSVTED 462
G+ YL KF + NA+ ++LW++L++A+ K D++++MD WT + G+P+++VT D
Sbjct: 450 GLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRD 509
Query: 463 GHKITFK--QNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDE---------REL 511
T K Q RYL V + V LS T + D + T + L
Sbjct: 510 YAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESL 569
Query: 512 TVTVEDV----DFIKTNANQAGIYVTSYSDDRW-----TTLSKQSDLLTVEDRTGLVADC 562
T++D+ ++ N + +Y +Y W T + + + V +R L+ D
Sbjct: 570 PKTIQDLPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDA 629
Query: 563 KTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTR 622
L+ +G + ++LI + E ++ W+ +L + P E + +
Sbjct: 630 LYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTP--DFEFFKRYMK 687
Query: 623 QL---VSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTS--- 676
+L + E + + FS LK + + + +
Sbjct: 688 KLILPIYEHLNGINDTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEAN 747
Query: 677 -GDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALM 735
+ N +P ++S+V+ T + G+ ++E L+ YK + + EK + L LG + L+
Sbjct: 748 PDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLL 807
Query: 736 KRTLGYLFD--GTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGS 793
+R L FD + QD + ++ G + +N D ++K + P +
Sbjct: 808 QRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSR 867
Query: 794 ILTVATSGFTSRQAIDEIEDFFKD--KSTKGFDQSLAQTLDTITSKANWVDRD 844
+L+ + + +E +DF + +S KG +Q++ QTL+ + + W +R+
Sbjct: 868 LLSPLSEQVITLSDFNEFKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQWKERN 920
>7301751 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1017
Score = 379 bits (973), Expect = e-104
Identities = 253/904 (27%), Positives = 452/904 (49%), Gaps = 83/904 (9%)
Query: 10 LPQNVSPLHYKLQLEPYFD-TFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKINDVK 68
LP ++ PL Y + +EP F F G+V I ++V + + + + +H ++N +
Sbjct: 132 LPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLE--------DCYNITMHAEELNISR 183
Query: 69 SLETVTDEENQTS--------RFKFPAGT------------LKDSDNVTIDIKFTGILND 108
S +V +N ++ G LKD + V + ++F GI+ D
Sbjct: 184 SDASVHRVQNNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYV-VHLRFDGIIED 242
Query: 109 TMAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHL 168
+ GFYR+ Y ET+++A+TQ + TDARRAFPCFDEP LKA+F + + +T +
Sbjct: 243 YLQGFYRSSY--EVHNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTI 300
Query: 169 SNMDVKKEE---IFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGS 225
SNM + + +F + MSTYLVA+ +++ ++ +F + R A +
Sbjct: 301 SNMPIVSSNDHATMPSYVWDHFAESLPMSTYLVAYAISDFTHISSGNFAVWARADAIKSA 360
Query: 226 EHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLD 285
E YA ++ + L+F + F + +PLPK+D +A+ EF AGAMENWGL+T+R +L D
Sbjct: 361 E----YALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYD 416
Query: 286 EKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWK 345
A+ +RVA VV HELAHQWFGNLVT WW +WLNEGFA++M + + PEWK
Sbjct: 417 PGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWK 476
Query: 346 VWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGE 405
+Q+V ++LQ+ LD+L +SH I V EI++IFD ISYAKGS+++RM++ +L
Sbjct: 477 QLDQFVVNELQAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTN 536
Query: 406 DVFVKGVSQYLNKFKFGNAKTEDLWDAL---SEASG-----KDVRNVMDIWTKKVGFPIV 457
+F +G+S+YL + + +A +DLW L +++SG + V+ +MD WT + G+P+V
Sbjct: 537 PIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVV 596
Query: 458 SVTE--DGHKITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLT---------- 505
V+ + I +Q R++ T + E++ L+ + ++ T+S ++ + T
Sbjct: 597 KVSRHPNSDVIRLEQVRFVYTNTTR-EDESLLWYIPITFTTDSELNFANTRPTTWMPRTK 655
Query: 506 ---LDERELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQ-SDLLTVED-----RT 556
L+ REL++ + N Q G Y +Y + W +++ D+ ED R
Sbjct: 656 LYELENRELSL----AKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRA 711
Query: 557 GLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEA 616
L+ D L+ Y S + + L +E V W+ I++ + + F +
Sbjct: 712 QLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDS--MFVNSGDYDL 769
Query: 617 LDEFTRQLVSEKTHSLGWEFSENES--YASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKY 674
L + + + + +G++ S++ES + + ++ F+ +
Sbjct: 770 LKNYLLKQLKKVYDQVGFKDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNW 829
Query: 675 ----TSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFE 730
+N I P ++ V+ + + G ++ F + + EK L LG +
Sbjct: 830 MQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFLKTNVPGEKDLLLNALGCSK 889
Query: 731 DPALMKRTLGYLFDGT-VLNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLT 789
+P L+ R L G + QD++ + G + + + NW + ++
Sbjct: 890 EPWLLYRFLRRGISGQHIRKQDLFRVFAAVSTTVVGQNIAFDFLRNNWQEIKTYMGSQMS 949
Query: 790 MLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKANWVDRDREVVV 849
+ ++ AT GF S+ + E E+F KD + +D+ + Q ++ I + +W++++ + +V
Sbjct: 950 SIHTLFKFATKGFNSKFQLGEFENFVKD-AHWDYDRPVQQIVEHIETSVDWMNKNYKSIV 1008
Query: 850 KFLK 853
++L+
Sbjct: 1009 RWLE 1012
>7299744 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 377 bits (968), Expect = e-104
Identities = 272/890 (30%), Positives = 440/890 (48%), Gaps = 58/890 (6%)
Query: 2 SSQPDRII--LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDI 59
++ P++I LP + P HY L L P +T +F G +I + V ++ +D + L++ L+I
Sbjct: 113 TASPEKIDYRLPGTLKPTHYDLYLFPNIETGEFSGQETITITV-EEATDQIVLHSLNLNI 171
Query: 60 HEAKINDVKS-----LETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFY 114
I + S LET D + F+ K V + I F G + + + G Y
Sbjct: 172 SSVSIMNTGSDTLEILETTVDAVREFLIFQLNEPLTKGR-TVRLHIGFEGSMANKIVGLY 230
Query: 115 RAKYIDNATGET-KYMATTQMEPTDARRAFPCFDEPNLKASFEITLV--SDPKLTHLSNM 171
+ Y+ ET K++AT++ EPT AR+AFPCFDEP LKA F ITLV S LSNM
Sbjct: 231 SSSYVKE--DETRKWIATSKFEPTYARQAFPCFDEPALKAEFTITLVHPSGEDYHALSNM 288
Query: 172 DVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEY----VECKDF--RIPVRVYATPGS 225
+V + F + MSTYL FIV++ Y ++ K + VYATP
Sbjct: 289 NVDSSVSQGAFQEVTFAKSVPMSTYLACFIVSDFAYKQVSIDTKGIGETFSMSVYATPEQ 348
Query: 226 EHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLD 285
A + + ++ F I YPLPK+D A+ +F +GAME+WGLVTYR LL D
Sbjct: 349 LDKVDLAVTIGKGVIEYYIDYFQIAYPLPKLDMAAIPDFVSGAMEHWGLVTYRETSLLYD 408
Query: 286 EKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWK 345
E +S +R+A V+ HE AH WFGNLVTM+WW LWLNEGFA+++ + + PEWK
Sbjct: 409 EATSSATNKQRIASVIAHEFAHMWFGNLVTMNWWNDLWLNEGFASFVEYLGVDAVYPEWK 468
Query: 346 VWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGE 405
+ S L LD SHPI V+ D+I +IFD I+Y+KGSSL+RM+ +LGE
Sbjct: 469 M------ASAPSVLTLDGTLGSHPIIQTVENPDQITEIFDTITYSKGSSLVRMLEDFLGE 522
Query: 406 DVFVKGVSQYLNKFKFGNAKTEDLWDALSEAS-GKDVRNVMDIWTKKVGFPIVS---VTE 461
F + V+ YLN++K+ A+T + + + + G +V +M WT ++G P+V+ V++
Sbjct: 523 TTFRQAVTNYLNEYKYSTAETGNFFTEIDKLELGYNVTEIMLTWTVQMGLPVVTIEKVSD 582
Query: 462 DGHKITFKQNRYLNT-----ADVKPEEDKTLYPVFLSLKTNS-GVDHSLTL--DERELTV 513
+K+T Q R+L+ AD +P E + + ++ T+S V L D+ E+TV
Sbjct: 583 TEYKLT--QKRFLSNPNDYDADHEPSEFNYRWSIPITYFTSSDSVVQRLWFYHDQSEITV 640
Query: 514 TV-EDVDFIKTNANQAGIYVTSYSDDRWTTLSKQSDLLTVE-------DRTGLVADCKTL 565
TV V++IK NA+Q G Y +Y D W L +D L V+ DR L+ D L
Sbjct: 641 TVPAAVEWIKFNADQVGYYRVNYDTDLWNDL---ADQLVVQPSAFGSVDRAHLLNDAFAL 697
Query: 566 SLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLV 625
+ S +L E +V W + L SLK + T ++ L+
Sbjct: 698 ADSTQLPYATAFELTRYLDKETDYVPWSVAASRLTSLKRTLYY--TSTYAKYKKYATALI 755
Query: 626 SEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPL 685
+L W + E + RL+V F + + +
Sbjct: 756 EPIYTALTW--TVGEDHLDNRLRVTALSAACSLGLESCLTEAGEQFNAWLAKPEDRPKAD 813
Query: 686 IKSSV-FGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLF- 743
++ +V + + G+ ++++ ++ ++ N S + EK + L + P +++R + +
Sbjct: 814 VRETVYYYGIQSVGSQEDWDAVWELFVNESDASEKSKLMYGLSAIQIPWILQRYIDLAWN 873
Query: 744 DGTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFT 803
+ V QD + + + + G +W + +ENW L +F + LG+++ T+ F+
Sbjct: 874 EEYVRGQDYFTCLTYISANPVGESLVWDYVRENWQRLVDRFGLNERYLGNLIPSITARFS 933
Query: 804 SRQAIDEIEDFFKDKSTKGFDQSL-AQTLDTITSKANWVDRDREVVVKFL 852
++ ++E+E FF G + + L+T+ + W+ + E V +L
Sbjct: 934 TQTKLEEMEQFFAKYPEAGAGTAARVRALETVKNNIVWLAENLEGVDAWL 983
>Hs11641261 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 960
Score = 373 bits (957), Expect = e-103
Identities = 269/892 (30%), Positives = 426/892 (47%), Gaps = 69/892 (7%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKINDVKS 69
LP V PLHY L + P + F + I++ V++ + F+ L++ +L+I A + +
Sbjct: 69 LPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNA-TQFIILHSKDLEITNATLQSEED 127
Query: 70 LETVTDEENQTSRFKFPAG---TLKDSDNVTIDIK------FTGILNDTMAGFYRAKYID 120
+ + + +PA L + +T +K F L D GFY++ Y
Sbjct: 128 SRYMKPGK-ELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTY-R 185
Query: 121 NATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMD-VKKEEIF 179
GET+ +A T EPT AR AFPCFDEP KA+F I + + + LSNM VK E+
Sbjct: 186 TLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELE 245
Query: 180 DGKKFTYFNPTPKMSTYLVAFIVAELEYVE-CKDFRIPVRVYATPGSEHLGQYAANLTAK 238
G +F T KMSTYLVA+IV + + + V +YA+P + YA + K
Sbjct: 246 GGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLK 305
Query: 239 TLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVA 298
L F+EK F I YPL K+D +A+ +F+ GAMENWGL+TYR LL D K +S V
Sbjct: 306 LLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVT 365
Query: 299 EVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSA 358
V+ HELAHQWFGNLVTM+WW +WL EGFA +M A N PE + ++ Y +
Sbjct: 366 RVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQ-FDDYFLNVCFEV 424
Query: 359 LGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNK 418
+ DSL SS PI P + +I ++FD +SY KG+ +L M+ +LGE+ F KG+ QYL K
Sbjct: 425 ITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKK 484
Query: 419 FKFGNAKTEDLWDALSEA---------------------------SGKDVRNVMDIWTKK 451
F + NAK +DLW +LS + +V+ +M WT +
Sbjct: 485 FSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQ 544
Query: 452 VGFPIVSVTEDGHKITFKQNRYL-NTADVKPE----EDKTLYPVFLSLKT-NSGVDHSLT 505
G P++ V +DG + +Q R+L PE +++ L+ + L+ T +S V H
Sbjct: 545 KGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHI 604
Query: 506 LDERELTVTV-EDVDFIKTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVA 560
L + T+ + E ++K N + G Y+ Y W T L++ LL +DR GL+
Sbjct: 605 LKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIH 664
Query: 561 DCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETL----EA 616
D L +G + L + ++E S ++ L L++ + + + E
Sbjct: 665 DVFQLVGAGRLTLDKALDMTYYLQHETSS---PALLEGLSYLESFYHMMDRRNISDISEN 721
Query: 617 LDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKY-- 674
L + Q W S+ S + L+ + +F ++
Sbjct: 722 LKRYLLQYFKPVIDRQSW--SDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWME 779
Query: 675 TSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPAL 734
+SG N IP + V+ A+ NY L Y+ SS E+ L L +
Sbjct: 780 SSGKLN-IPTDVLKIVYSVGAQTTAGWNY--LLEQYELSMSSAEQNKILYALSTSKHQEK 836
Query: 735 MKRTLGYLFDGTVL-NQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGS 793
+ + + +G V+ Q++ + + +G + W + +ENW L KKF +
Sbjct: 837 LLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRM 896
Query: 794 ILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQT-LDTITSKANWVDRD 844
I++ T+ F+S+ + E++ FF+ +G + QT L+TIT W++++
Sbjct: 897 IISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKN 948
>At4g33090 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 873
Score = 371 bits (952), Expect = e-102
Identities = 270/906 (29%), Positives = 417/906 (45%), Gaps = 133/906 (14%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN---- 65
LP+ P Y L+L P F GTV+IDL + ++ F+ LN +L +++A ++
Sbjct: 10 LPKFAVPKRYDLRLNPDLIACTFTGTVAIDLDIV-ADTRFIVLNAADLSVNDASVSFTPP 68
Query: 66 -DVKSL---ETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYID- 120
K+L + V EE++ +F G + + + F G+LND M GFYR+ +
Sbjct: 69 SSSKALAAPKVVLFEEDEILVLEF--GEILPHGVGVLKLGFNGVLNDKMKGFYRSSRLIL 126
Query: 121 ------------NATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHL 168
GE K MA TQ EP DARR FPC+DEP KA+F+ITL L L
Sbjct: 127 ERSCICLGGSTYEHNGEKKNMAVTQFEPADARRCFPCWDEPACKATFKITLEVPTDLVAL 186
Query: 169 SNMDVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHL 228
SNM + +E++ K + +P MSTYLVA +V +YVE P + T
Sbjct: 187 SNMPIMEEKVNGNLKIVSYQESPIMSTYLVAIVVGLFDYVEDHTSDGPSLTFETL----- 241
Query: 229 GQYAANLTAKTLSFFE-------------KAFGIEYPLPKMDSVAVHEFSAGAMENWGLV 275
LSFF + F + YPLPKMD +A+ +F+AGAMEN+GLV
Sbjct: 242 ------CACIFLSFFNGCIISLHKSNHSCRYFAVPYPLPKMDMIAIPDFAAGAMENYGLV 295
Query: 276 TYRVVDLLLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWY 335
TYR LL DE++++ +RV S+
Sbjct: 296 TYRETALLYDEQHSAASNKQRV-----------------------------------SYL 320
Query: 336 ACNQFQPEWKVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSL 395
A + PEWK+W Q++ D+ L LD L SHPIEV V A EI++IFD ISY KG+S+
Sbjct: 321 ATDSLFPEWKIWTQFL-DESTEGLRLDGLEESHPIEVEVNHAAEIDEIFDAISYRKGASV 379
Query: 396 LRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFP 455
+RM+ +LG +VF K ++ Y+ + NAKTEDLW AL SG+ V +M WTK+ G+P
Sbjct: 380 IRMLQSYLGAEVFQKSLAAYIKNHAYSNAKTEDLWAALEAGSGEPVNKLMSSWTKQKGYP 439
Query: 456 IVSVTEDGHKITFKQNRYLNTADVKPEEDKTLYPVFLS-----------LKTNSGVDHSL 504
+VS K+ +Q+R+L++ P E + + PV L L++ SG
Sbjct: 440 VVSAKIKDGKLELEQSRFLSSG--SPGEGQWIVPVTLCCGSYEKRKNFLLESKSG----- 492
Query: 505 TLDERELT-VTVED--------VDFIKTNANQAGIYVTSYSDDRWTTL--SKQSDLLTVE 553
D +EL ++ D +IK N +QAG Y Y D L + +S LT
Sbjct: 493 AYDLKELLGCSIADGSDKINGTCSWIKINVDQAGFYRVKYDDSLAAGLRNATESQSLTSI 552
Query: 554 DRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKET 613
DR G++ D L+++ S + L L S +K E + V +I + A +E
Sbjct: 553 DRYGILDDSFALTMARQQSLASLLTLCSAYKKELDYTVLSNLIAISYKVVKIGADANQEL 612
Query: 614 LEALDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEK 673
+ + F + LGW+ + ES+ L+ E+ F+
Sbjct: 613 MSGIKHFFIGVFQFAAGKLGWDPKQGESHLDAMLRGEVLTALAVFGHDETLKEAVRRFDA 672
Query: 674 YTSG-DSNAIPPLIKSSVFGTVARDGNAKN---YEKLFAIYKNPSSSDEKLSALRCLGRF 729
+ + ++ +PP I+ + + V + N + YE L +Y+ S EK L L
Sbjct: 673 FLADRNTPLLPPDIRRAAYVAVMQRANKSDKSGYESLLRVYRETDLSQEKTRILGSLASC 732
Query: 730 EDPALMKRTLGYLFDG-------------TVLNQDIYIPMGGMRGHKEGIKTLWAWTKEN 776
DP +++ L ++ V NQD + G+ EG + W W +E
Sbjct: 733 PDPTIVQDVLNFVLSDEVDYMDFAFHSVELVRNQDALYGLSGVSW--EGREVAWKWLQEK 790
Query: 777 WDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITS 836
W+ + + ++ ++ S F S + E+E+FF +S ++L Q+++ +
Sbjct: 791 WEYIGNTWGSGF-LITRFISAVVSPFASFEKAKEVEEFFATRSKPSMARTLKQSIERVHI 849
Query: 837 KANWVD 842
ANWV+
Sbjct: 850 NANWVE 855
>7301771 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1082
Score = 362 bits (928), Expect = 2e-99
Identities = 261/892 (29%), Positives = 431/892 (48%), Gaps = 66/892 (7%)
Query: 10 LPQNVSPLHYKLQLEPYF---DTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIND 66
LP + P Y L++ D +F G V I +K + + L++ L I E++I
Sbjct: 29 LPTALRPQRYYLRILTLLESPDDLRFAGNVQIVIKALQNTRN-ITLHSKNLTIDESRIT- 86
Query: 67 VKSLETVTDEENQTSRFK-------FPAGTLKD--SDNV-TIDIKFTGILNDTMAGFYRA 116
++ + + +N S + T K+ + NV + + F+ L + G+YR+
Sbjct: 87 LRQISGAGNMDNCVSSTSVNPTHDYYIFHTCKELLAGNVYKLFLPFSADLTPQLFGYYRS 146
Query: 117 KYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKK- 175
Y D T +T++++ TQ EP+ AR+AFPCFDEP KASF +TL + LSNM V++
Sbjct: 147 SYKDPVTNKTRWLSATQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREI 206
Query: 176 --EEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIP----VRVYATPGSEHLG 229
E + F + MSTYLVA+ V + + K +P R +A P +
Sbjct: 207 RPHESLANYIWCEFQESVPMSTYLVAYSVNDFSF---KPSTLPNGALFRTWARPNAIDQC 263
Query: 230 QYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNA 289
YAA K L ++E+ FGI YPLPK+D +AV +FSAGAMENWGLV YR LL ++
Sbjct: 264 DYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVPDFSAGAMENWGLVKYRESTLLYSPTHS 323
Query: 290 SLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQ 349
SL + +A V+ HELAHQWFGNLVTM WW LWLNEGFAT+++ + PEW ++
Sbjct: 324 SLADKQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRDK 383
Query: 350 YVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFV 409
L +A LDSL SSHPI P++ EI + FD ISY KGS++LRM+ ++GE+ F
Sbjct: 384 GSLTALMTAFRLDSLVSSHPISRPIQMVTEIEESFDAISYQKGSAVLRMMHLFMGEESFR 443
Query: 410 KGVSQYLNKFKFGNAKTEDLWDALSEASGK--------DVRNVMDIWTKKVGFPIVSVTE 461
G+ +YL + + NA+ +LW++L+ A+ + D+ +MD WT + GFP++++T
Sbjct: 444 TGLREYLKLYAYKNAEQNNLWESLTTAAHQNGALPGHYDINTIMDSWTLQTGFPVLNITR 503
Query: 462 DGHKIT--FKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDE--RELTVTVED 517
D T Q RYL + + + + V LS T D + T + E + T E
Sbjct: 504 DYSTGTAEITQERYLRNSQIPQADRVGCWWVPLSYTTQDENDFNNTSPKAWMECSSTDEG 563
Query: 518 V-----------DFIKTNANQAGIYVTSYSDDRWTTL-----SKQSDLLTVEDRTGLVAD 561
V +++ N + Y +Y W L SK + V +R L+ D
Sbjct: 564 VPTTIDHSAGPEEWLILNIQLSTPYKANYDARNWKLLIDTLNSKDFQSIHVINRAQLIDD 623
Query: 562 CKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFT 621
+ +G + LQ+ + + E + W+ +++L L P + +
Sbjct: 624 VLYFAWTGEQDYETALQVTNYLRRERDLIPWKSALDNLKLLNRILRQTP--NFGSFKRYM 681
Query: 622 RQLVS---EKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKY---T 675
++L++ E H + FS LK + F ++ T
Sbjct: 682 QKLLTPIYEHLHGMNDTFSLMTQQDEVLLKTTVVNVACQYDVSDCVTQAQAYFRRWRAET 741
Query: 676 SGDSNAIPPL-IKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPAL 734
+ D N PL ++S+V+ T G +++ L++ Y+ + + E+ + L LG ++ +
Sbjct: 742 NPDENHPVPLNLRSTVYCTAISQGTEEDWNFLWSRYRKSNVASERQTILSTLGCSKEVWI 801
Query: 735 MKRTLGYLF--DGTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLG 792
++R + F + QD + + + G + EN + +HK + P ++
Sbjct: 802 LQRYMEKSFHPKSAIRKQDSSLCFQAVASREVGFLLAKQYFIENVELIHKYYYPQTRVMS 861
Query: 793 SILTVATSGFTSRQAIDEIEDFFKDKS--TKGFDQSLAQTLDTITSKANWVD 842
+LT + ++ +++ F D KG Q++ Q+L+T+ + + D
Sbjct: 862 RLLTPLSEQVSTINDLNKFRSFANDSRHFLKGIRQAMQQSLETMLTNLEYAD 913
>Hs7019561 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1024
Score = 355 bits (910), Expect = 2e-97
Identities = 240/877 (27%), Positives = 425/877 (48%), Gaps = 57/877 (6%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKINDVKS 69
L ++ PLHY L L + + F F G V++++ + + +V L+ + + + ++ + ++
Sbjct: 141 LSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNA-TRYVVLHASRVAVEKVQLAEDRA 199
Query: 70 LETVTDEENQTSRFKFPAG---------TLKDSDNVTIDIKFTGILNDTMAGFYRAKYID 120
V F +P TL N + I + ++ + + GF+R+ Y+
Sbjct: 200 FGAVP----VAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVL 255
Query: 121 NATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF- 179
+ GE +++ TQ PT AR+AFPCFDEP KA+F+I++ LSNM V+ +F
Sbjct: 256 H--GERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETS-VFE 312
Query: 180 -DGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGS--EHLGQYAANL 235
DG +F+ TP MSTY +A+ + Y E + VR+YA P + G YA ++
Sbjct: 313 EDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHI 372
Query: 236 TAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIK 295
T + + F+E F + Y LPK+D +AV + AMENWGL + +LLD +S+ +
Sbjct: 373 TKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLL 432
Query: 296 RVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQ-YVADD 354
V V+ HE+ HQWFG+LVT WWE +WL EGFA + + + P W + +Q ++ D
Sbjct: 433 DVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDV 492
Query: 355 LQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQ 414
L + LD L SSHP+ V +A +I+++FD I+Y KG++L+RM++ ++G VF +G+
Sbjct: 493 LHEVMLLDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQD 552
Query: 415 YLNKFKFGNAKTEDLWDALSEA---SGK--DVRNVMDIWTKKVGFPIVSV---TEDGHKI 466
YL K+GNA DLW+ LSEA +GK +++ VMD WT ++G+P++++ T ++I
Sbjct: 553 YLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRI 612
Query: 467 TFKQNRYL-----NTADVKPEEDKTLY--PVFLSLKTNSGVDHSLTL-----DERELTVT 514
Q ++ T +K + + L+ P+ + + S V + E
Sbjct: 613 IITQQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITY 672
Query: 515 VEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQ----SDLLTVEDRTGLVADCKTLSLSGY 570
++ ++ N NQ G + +Y W L Q ++L+V +R GL+ D +L+ +GY
Sbjct: 673 LDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGY 732
Query: 571 TSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTH 630
L++I E F+ W +L L + E +E+ + V+
Sbjct: 733 LPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDK--LLDRMENYNIFNEYILKQVATTYI 790
Query: 631 SLGWEFSE------NESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPP 684
LGW + SY + L+ E+ + + S + N IP
Sbjct: 791 KLGWPKNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPL 850
Query: 685 LIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGY-LF 743
++ V+ T + +E ++ + + ++ EK L L +D L+ R L L
Sbjct: 851 NVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLNRLLNLSLN 910
Query: 744 DGTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFT 803
VL+QD + + + G W + ++ W L+ ++ +L M +++ T
Sbjct: 911 SEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLN 970
Query: 804 SRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKANW 840
+ + E+++F K+ S ++ ++T+ + W
Sbjct: 971 TEGELKELKNFMKNYDGVA-AASFSRAVETVEANVRW 1006
>CE21162 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 347 bits (889), Expect = 6e-95
Identities = 254/906 (28%), Positives = 433/906 (47%), Gaps = 69/906 (7%)
Query: 10 LPQNVSPLHYKLQLEPYF---------DTFKFDGTVSIDLKVNDKESDFVELNTFELDIH 60
LP +VSP+ Y+L ++ Y + F+G V I+L + K V LN+ +L+
Sbjct: 86 LPTSVSPISYQLTVKTYLPGYGYTADKNNLTFEGQVLIELNIT-KSIKKVSLNSKDLNYT 144
Query: 61 EAKIN------DVKSLETVTDEENQTSRFKF--PAGTLKDSDNVTIDIKFTGILNDTMAG 112
E I + KS+ D++ T F T++ + + T+ + F L M+G
Sbjct: 145 EEFIKKSSILVNGKSIAFTLDDKQSTHEKIFFNLDETVEPTTSATLKVAFGAPLRTDMSG 204
Query: 113 FYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSN-M 171
Y+ Y N+ GE+K A TQMEP ARR PCFDEP KA++ +T++ K +SN +
Sbjct: 205 LYQTTYT-NSKGESKMAAVTQMEPVYARRMVPCFDEPAYKATWTVTVIHPNKTVAVSNGI 263
Query: 172 DVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGSEHLGQ 230
+ K E+ G + F PTP+MS+YL+A ++E EY E + RV++ P ++
Sbjct: 264 EDKVEDGQPGFIISTFKPTPRMSSYLLAIFISEFEYNEATTKSGVRFRVWSRPEEKNSTM 323
Query: 231 YAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNAS 290
YA K L ++EK + I +PLPK D VA+ +FSAGAMENWGL+TYR LL D + S
Sbjct: 324 YAVEAGVKCLEYYEKYYNISFPLPKQDMVALPDFSAGAMENWGLITYRESALLYDPRIYS 383
Query: 291 LERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQP-EWKVWEQ 349
+ +RVA V+ HELAHQWFGNLVT+ WW LWLNEGFAT + + ++ ++ E
Sbjct: 384 GSQKRRVAVVIAHELAHQWFGNLVTLKWWNDLWLNEGFATLVEYLGTDEISDGNMRMREW 443
Query: 350 YVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFV 409
+ D L SAL DS+ S+HP+ + +A E+ FD ++Y KG ++L M+ + +GE+ F
Sbjct: 444 FTMDALWSALAADSVASTHPLTFKIDKAMEVLDSFDSVTYDKGGAVLAMVRKTIGEENFN 503
Query: 410 KGVSQYLNKFKFGNAKTEDLWDALSE----------ASGKDVRNVMDIWTKKVGFPIVSV 459
G++ YL + +F NA +L AL E ++ MD WTK++G+P+++
Sbjct: 504 TGINHYLTRHQFDNADAGNLLTALGEKIPDSVMGPKGVKLNISEFMDPWTKQLGYPLLNA 563
Query: 460 TE-DGHKITFKQNRYLNTADVKPEED--------KTLYPVFLSLKTNSGVDHSLTLDERE 510
+ + I +Q+R+ A K EE K PV+ + +S ++ + +R
Sbjct: 564 SRINNTHIIVEQSRFKLLATGKEEEKYSNPVWGFKWDVPVWYQVVGSSELE--MKWMKRN 621
Query: 511 LTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLS----KQSDLLTVEDRTGLVADCKTLS 566
+ ++ + NA G Y YS W +S + + + + R L+ D L+
Sbjct: 622 EPLIIKSDKNVIINAESNGFYRAGYSSGLWKEISEMLKENHEQFSPQTRVRLIDDSFALA 681
Query: 567 LSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVS 626
+G S L LI+ KNE ++ W I + L + P++ + +++F L
Sbjct: 682 RAGLLSYSIPLNLITYLKNEKEYLPWSGAIAKIRELIDMYGSNPEK--DIVNKFMIALAE 739
Query: 627 EKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXX---XXXXXXXXMFEKYTS------- 676
+F +++Y ++ E+ M + +T
Sbjct: 740 NAPARRSIDF-VSKNYLDEKKFYEVGAAQQIILNSCGFGDSVCQADMVKMFTEEVLAKCD 798
Query: 677 -----GDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFED 731
+ + IP ++ + R+GN+ +EK+F YK + EKL+ + L +D
Sbjct: 799 ATRILSECSQIPAPFRAESYCEAVRNGNSDTFEKVFHWYKTERNQVEKLNLMTALTCSKD 858
Query: 732 PALMKRTL--GYLFDGTVLN-QDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSL 788
+K+ L +G+ QD + + + + + W+ + K+
Sbjct: 859 ILTLKKLLLDAMKPEGSSFRLQDCAALFAKISSNDATTDAMLNFLIDRWEDMQKRLATDH 918
Query: 789 TMLGSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKANWVDRDREVV 848
+ +L+ + +R +D++ F K K+ K + L + ++ W + + + V
Sbjct: 919 SGFSRVLSSIVNTLKTRGGLDQLRKFRK-KAPKASEFGLDKMEESAEVTVTWRETNLKFV 977
Query: 849 VKFLKE 854
K ++E
Sbjct: 978 TKIIEE 983
>ECU08g0070 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 343 bits (881), Expect = 5e-94
Identities = 219/641 (34%), Positives = 339/641 (52%), Gaps = 39/641 (6%)
Query: 2 SSQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHE 61
SSQ R L + V P HY L ++ D F G+V I + ++ S+ V LN EL+I +
Sbjct: 24 SSQQRR--LSRVVVPEHYDLHVK-ILDA-GFCGSVGIRVMISQDVSEIV-LNAKELEIRD 78
Query: 62 AKIN------DVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYR 115
A I + + ++E + R FP+ +T++ F G N+ + G Y+
Sbjct: 79 AGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTME--FCGDYNNGLVGLYK 136
Query: 116 AKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDV-- 173
+ G K + +T EPTDAR FPCFD+P++KA+F+I++ + K T L+N
Sbjct: 137 S-------GGPKEVYSTHFEPTDARWVFPCFDQPDMKATFKISIDAGSKFTVLANTQAIP 189
Query: 174 KKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVE--CKDFRIPVRVYATPGSEHLGQY 231
E + +K YF T KMSTYLVAF+V EL Y+E KD + +RVY G+Y
Sbjct: 190 SLREEYGDRKIEYFEETCKMSTYLVAFVVGELSYIEDWSKD-GVRLRVYGDSSEVEWGRY 248
Query: 232 AANLTAKTLSFFEKAFGIEYPLP-----KMDSVAVHEFSAGAMENWGLVTYRVVDLLLDE 286
+ + L +F + FG+ Y P K+D V + FS+GAMENWGL+T+R LL
Sbjct: 249 GLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYVP 308
Query: 287 KNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQP--EW 344
+++E +K VAE V HEL H WFGNLVTM WW+ LWLNEGFATW+S+ W
Sbjct: 309 GKSNVEDMKNVAETVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVVSW 368
Query: 345 KVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLG 404
VW ++V ++ + D L SH I + V EI +IFD ISY KG+S++RMI +++G
Sbjct: 369 DVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIERYVG 428
Query: 405 EDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGH 464
E VF+ G+ +Y+ + +GN LW A+ E G+D+ +++ W + G+P+VSV + G
Sbjct: 429 ESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQDCGS 488
Query: 465 KITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTN 524
+ Q+RY + + D +L+ + + + + L RE TV K N
Sbjct: 489 SLVLSQSRY----SMLGKSDDSLWTIPVVVSWEGKGQERIELRGRETTVRKRS-SVYKVN 543
Query: 525 ANQAGIYVTSYSDDRWTTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWK 584
A G Y Y + L + D L+V DR ++ D L Y ++ L+ IS++
Sbjct: 544 AEYGGFYRVLYDSAGLSGLESRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRISEYY 603
Query: 585 NEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLV 625
+ DS+ V I L L++ + ++ E + +D+ R+++
Sbjct: 604 S-DSYHVARSGIEKLLRLRSVF-YDDAEIVSLIDKKVRKMI 642
>ECU01g1470 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 343 bits (881), Expect = 5e-94
Identities = 219/641 (34%), Positives = 340/641 (52%), Gaps = 39/641 (6%)
Query: 2 SSQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHE 61
SSQ R L + V P HY L ++ D F G+V I + ++ S+ V LN EL+I +
Sbjct: 24 SSQQRR--LSRVVVPEHYDLHVK-ILDA-GFCGSVGIRVMISQDVSEIV-LNAKELEIRD 78
Query: 62 AKIN------DVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYR 115
A I + + ++E + R FP+ +T++ F G ++ + G Y+
Sbjct: 79 AGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTME--FCGDYSNGLVGLYK 136
Query: 116 AKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDV-- 173
+ G K + +T EPTDARRAFPCFD+P++KA+F+I++ + K T L+N
Sbjct: 137 S-------GGPKEVYSTHFEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIP 189
Query: 174 KKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVE--CKDFRIPVRVYATPGSEHLGQY 231
E + +K YF T KMSTYLVAF+V EL Y+E KD + +RVY G+Y
Sbjct: 190 SLREEYGDRKIEYFEETCKMSTYLVAFVVGELSYIEDWSKD-GVRLRVYGDSSEVEWGRY 248
Query: 232 AANLTAKTLSFFEKAFGIEYPLP-----KMDSVAVHEFSAGAMENWGLVTYRVVDLLLDE 286
+ + L +F + FG+ Y P K+D V + FS+GAMENWGL+T+R LL
Sbjct: 249 GLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYVP 308
Query: 287 KNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQP--EW 344
+++E +K VA V HEL H WFGNLVTM WW+ LWLNEGFATW+S+ W
Sbjct: 309 GKSNVEDMKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVVSW 368
Query: 345 KVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLG 404
VW ++V ++ + D L SH I + V EI +IFD ISY KG+S++RMI +++G
Sbjct: 369 DVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIERYVG 428
Query: 405 EDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGH 464
E VF+ G+ +Y+ + +GN LW A+ E G+D+ +++ W + G+P+VSV + G
Sbjct: 429 ESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQDCGS 488
Query: 465 KITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTN 524
+ Q+RY + + D +L+ + + + + L RE TV K N
Sbjct: 489 SLVLSQSRY----SMLGKSDDSLWTIPVVVSWEGKGQERIELRGRETTVRKRS-SVYKVN 543
Query: 525 ANQAGIYVTSYSDDRWTTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWK 584
A G Y Y + L + D L+V DR ++ D L Y ++ L+ IS++
Sbjct: 544 AEYGGFYRVLYDSAGLSGLESRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRISEYY 603
Query: 585 NEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLV 625
+ DS+ V I L L++ + ++ E + +D+ R+++
Sbjct: 604 S-DSYHVARSGIEKLLRLRSVF-YDDAEIVSLIDKKVRKMI 642
>ECU01g0140 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 864
Score = 343 bits (881), Expect = 5e-94
Identities = 219/641 (34%), Positives = 340/641 (52%), Gaps = 39/641 (6%)
Query: 2 SSQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHE 61
SSQ R L + V P HY L ++ D F G+V I + ++ S+ V LN EL+I +
Sbjct: 24 SSQQRR--LSRVVVPEHYDLHVK-ILDA-GFCGSVGIRVMISQDVSEIV-LNAKELEIRD 78
Query: 62 AKIN------DVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYR 115
A I + + ++E + R FP+ +T++ F G ++ + G Y+
Sbjct: 79 AGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTME--FCGDYSNGLVGLYK 136
Query: 116 AKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDV-- 173
+ G K + +T EPTDARRAFPCFD+P++KA+F+I++ + K T L+N
Sbjct: 137 S-------GGPKEVYSTHFEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIP 189
Query: 174 KKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVE--CKDFRIPVRVYATPGSEHLGQY 231
E + +K YF T KMSTYLVAF+V EL Y+E KD + +RVY G+Y
Sbjct: 190 SLREEYGDRKIEYFEETCKMSTYLVAFVVGELSYIEDWSKD-GVRLRVYGDSSEVEWGRY 248
Query: 232 AANLTAKTLSFFEKAFGIEYPLP-----KMDSVAVHEFSAGAMENWGLVTYRVVDLLLDE 286
+ + L +F + FG+ Y P K+D V + FS+GAMENWGL+T+R LL
Sbjct: 249 GLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYVP 308
Query: 287 KNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQP--EW 344
+++E +K VA V HEL H WFGNLVTM WW+ LWLNEGFATW+S+ W
Sbjct: 309 GKSNVEDMKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVVSW 368
Query: 345 KVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLG 404
VW ++V ++ + D L SH I + V EI +IFD ISY KG+S++RMI +++G
Sbjct: 369 DVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIERYVG 428
Query: 405 EDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGH 464
E VF+ G+ +Y+ + +GN LW A+ E G+D+ +++ W + G+P+VSV + G
Sbjct: 429 ESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQDCGS 488
Query: 465 KITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTN 524
+ Q+RY + + D +L+ + + + + L RE TV K N
Sbjct: 489 SLVLSQSRY----SMLGKSDDSLWTIPVVVSWEGKGQERIELRGRETTVRKRS-SVYKVN 543
Query: 525 ANQAGIYVTSYSDDRWTTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWK 584
A G Y Y + L + D L+V DR ++ D L Y ++ L+ IS++
Sbjct: 544 AEYGGFYRVLYDSAGLSGLESRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRISEYY 603
Query: 585 NEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLV 625
+ DS+ V I L L++ + ++ E + +D+ R+++
Sbjct: 604 S-DSYHVARSGIEKLLRLRSVF-YDDAEIVSLIDKKVRKMI 642
>7299745 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 913
Score = 340 bits (873), Expect = 4e-93
Identities = 248/879 (28%), Positives = 410/879 (46%), Gaps = 82/879 (9%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKINDVKS 69
LP N+ P HY+L P +T F G I +KV + + + L+++ LDI + + +
Sbjct: 68 LPTNLVPTHYELYWHPDLETGNFTGQQRISIKVVEATNQII-LHSYLLDITSVYVLNREV 126
Query: 70 LETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGETKYM 129
+ +EE Q D+ ++T+ I F G + D + G Y + Y++ A G T+ +
Sbjct: 127 EKFELEEERQFLIITLTEELAVDA-SITLGIIFGGQMKDKLVGLYSSTYLNEA-GATRTI 184
Query: 130 ATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTH-LSNMDVKKEEIFDGKKFTYFN 188
+TT+ EPT AR+AFPCFDEP +KA+F IT+V H +SNM + F
Sbjct: 185 STTKFEPTYARQAFPCFDEPAMKATFAITVVHPSGSYHAVSNMQQTESNYLGDYTEAIFE 244
Query: 189 PTPKMSTYLVAFIVAELEYVEC--------KDFRIPVRVYATPGSEHLGQYAANLTAKTL 240
+ MSTYLV IV++ +DF + + YAT + ++A
Sbjct: 245 TSVSMSTYLVCIIVSDFASQSTTVKANGIGEDFSM--QAYATSHQINKVEFALEFGQAVT 302
Query: 241 SFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEV 300
++ + + + YPL K+D A+ +F++GAME+WGLVTYR LL D +S + +A
Sbjct: 303 EYYIQYYKVPYPLTKLDMAAIPDFASGAMEHWGLVTYRETALLYDPSYSSTANKQSIAGT 362
Query: 301 VQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALG 360
+ HE+AHQWFGNLVTM WW LWLNEGFA +M + N P+W + EQ+ LQ L
Sbjct: 363 LAHEIAHQWFGNLVTMKWWNDLWLNEGFARYMQYKGVNAVHPDWGMLEQFQIVALQPVLL 422
Query: 361 LDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFK 420
D+ SSHPI V+ DEI IFD ISY KG S++RM+ +G + F + V+ YL K +
Sbjct: 423 YDAKLSSHPIVQKVESPDEITAIFDTISYEKGGSVIRMLETLVGAEKFEEAVTNYLVKHQ 482
Query: 421 FGNAKTED-LWDALSEASGKDVRNVMDIWTKKVGFPIVSVTE--DG-HKITFKQNRYL-N 475
F N T+D L + + + D++ +M WT+++G+P+++V++ DG K+T Q R+L N
Sbjct: 483 FNNTVTDDFLTEVEAVVTDLDIKKLMLTWTEQMGYPVLNVSKVADGSFKVT--QQRFLSN 540
Query: 476 TADVKPEEDKTLY----PVFLSLKTNSGVDHSLTLDERELTVTV---EDVDFIKTNANQA 528
A + + Y V ++ + G ++S D +V + +V +IK N NQ
Sbjct: 541 PASYEEAPSDSAYGYKWSVPITWFADDGSENSFIYDYDVDSVGIAVPSEVQWIKLNVNQT 600
Query: 529 GIYVTSYSDDRWTTLSKQSDL----LTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWK 584
G Y +Y + W L +Q + DR L+ D L+ + S K L + +
Sbjct: 601 GYYRVNYEESLWALLIQQLTTSPARFEIADRGHLLNDAFALADANQLSYKIPLDMTAYLA 660
Query: 585 NEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYAS 644
E FV L++ +GW + +++
Sbjct: 661 QERDFVPC-------------------------------LIAGVYEEVGWTV-DADNHLK 688
Query: 645 QRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSV-FGTVARDGNAKNY 703
RL+V + F + + P ++ V + + + + ++
Sbjct: 689 NRLRVSILTAACALGVPDCLQQASERFSTFLENPTTRPSPDLREIVYYYGMQQSTSQSSW 748
Query: 704 EKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFD---------GTVLNQDIYI 754
++LF ++ + + EKL + L R YLFD V +QD +
Sbjct: 749 DQLFQLFVAETDASEKLKLMYGLSGV-------RNSQYLFDFLAQASSDESIVRSQDYFT 801
Query: 755 PMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDF 814
+ + + G +W + +E W L +F + G ++ T+ F S ++E++ F
Sbjct: 802 CVQYIAANPVGEPVVWEFYREQWPQLTTRFGLNNRNFGRLIAQITANFASSVKLEEVQHF 861
Query: 815 FKDKSTKGFD-QSLAQTLDTITSKANWVDRDREVVVKFL 852
F G S + ++TI W+ R+ + +L
Sbjct: 862 FSKYPESGAGANSRLEAVETIKYNIEWLSRNEADITDWL 900
>Hs22064092 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 478
Score = 325 bits (834), Expect = 1e-88
Identities = 182/427 (42%), Positives = 258/427 (59%), Gaps = 9/427 (2%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKI---ND 66
LP +VSP++ L L+P F F+G + +V + V +N ++DI A D
Sbjct: 54 LPADVSPINCSLCLKPDLLDFTFEGKLEAAAQVRQATNQIV-MNCADIDIITASYAPEGD 112
Query: 67 VKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGET 126
+ T + +N+ + + + T+ I F G LND M GFYR+KY +GE
Sbjct: 113 EEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYT-TPSGEV 171
Query: 127 KYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTY 186
+Y A TQ E TDARRAFPC+DE +KA+F+I+LV LSNM+V + + +
Sbjct: 172 RYAAVTQFEATDARRAFPCWDERAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLV 231
Query: 187 ---FNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGSEHLGQYAANLTAKTLSF 242
F TP STYLVAF+V E ++VE + + V VY G G++A + AKTL F
Sbjct: 232 EVKFARTPVTSTYLVAFVVGEYDFVETRSKDGVCVCVYTPVGKAEQGKFALEVAAKTLPF 291
Query: 243 FEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQ 302
++ F + YPLPK+D +A+ +F+AGAMENW LVTYR LL+D KN+ + VA VV
Sbjct: 292 YKDYFNVPYPLPKIDLIAIADFAAGAMENWDLVTYRETALLIDPKNSCSSSRQWVALVVG 351
Query: 303 HELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGLD 362
HELAHQWFGNLVTM+WW L LNEGFA+W+ + + PE+ +W Q+V+ D A LD
Sbjct: 352 HELAHQWFGNLVTMEWWTHLRLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELD 411
Query: 363 SLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFG 422
+L +SHPIEV V E+++IFD ISY+KG+S++RM+ ++G+ F KG++ YL KF+
Sbjct: 412 ALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQK 471
Query: 423 NAKTEDL 429
NA +L
Sbjct: 472 NAAAGNL 478
>7300769 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1646
Score = 318 bits (816), Expect = 2e-86
Identities = 229/877 (26%), Positives = 421/877 (47%), Gaps = 70/877 (7%)
Query: 10 LPQNVSPLHYKLQLEPYF------DTFKFDGTVSIDLKVNDKESD-FVELNTFELDIHE- 61
L ++++P++Y + L PY F FDG V I++ N +D ++ + E
Sbjct: 43 LAEHITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQTTNDIYLHSKNLTYSVREY 102
Query: 62 --AKINDVKSLETVTDEENQTSRF-----KFPAGT-LKDSDNVTIDIKFTGILNDTMAGF 113
+V + + T+ + K A T L + + +TG++ D M GF
Sbjct: 103 WQKPTTEVANPTVIQISATNTTNYDTDIVKLTASTALTANTTYILHFVYTGLMEDDMHGF 162
Query: 114 YRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITL--------VSDPKL 165
YR+ Y+D+ TK++ +TQ + ARRAFP FDEP KA+F++TL VS+ +L
Sbjct: 163 YRSSYVDD-NNVTKWLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRL 221
Query: 166 THLSNMDVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGS 225
+S+ +E IF + TPKMSTYL+AFI++E + DF VYA P
Sbjct: 222 --ISSYPSTEEGIFSD----VYKTTPKMSTYLLAFIISEFVARKDDDFG----VYARPEY 271
Query: 226 EHLGQYAANLTAKTLSFFEKAFGIEYPL---PKMDSVAVHEFSAGAMENWGLVTYRVVDL 282
QY N+ + L + +Y KMD A+ +FSAGAMENWGL+TYR L
Sbjct: 272 YAQTQYPYNVGIQILEEMGQYLDKDYYSMGNDKMDMAAIPDFSAGAMENWGLLTYRERSL 331
Query: 283 LLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQP 342
L+DE +L + +A VV HE AH WFG+LVT WW WLNEGFA + ++ +
Sbjct: 332 LVDESATTLASRQSIAAVVAHEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVED 391
Query: 343 EWKVWEQYVADDLQSALGLDSLRSSHPI-EVPVKRADEINQIFDHISYAKGSSLLRMISQ 401
+W++ +Q+V D +QS + +DS +++P+ + ++++F+ ISY KG++ +RMI
Sbjct: 392 KWELEKQFVVDQVQSVMAMDSTNATNPLSDENTYTPAHLSRMFNSISYNKGATFIRMIKH 451
Query: 402 WLGEDVFVKGVSQYLNKFKFGNAKTEDL---WDA--LSEASGKDVRNVMDIWTKKVGFPI 456
+GE F K + +YL K+++ ++ E L W A + + + +++ +T++VG+P+
Sbjct: 452 TMGEQQFQKSLQEYLKKYEYQSSLPEYLLGAWQANWPNSSYNESSKDIFKSFTEQVGYPL 511
Query: 457 VSVTEDGHKITFKQNRY-LNTADVKPEEDKTLYPV-FLSLKTNSGVDHS-LTLDERELTV 513
++VT +++F Q R+ L +D K P+ + + +TN+ ++ + + + +T
Sbjct: 512 INVTVGNSQVSFTQKRFLLKESDGSDSSLKYTVPISYTTSETNNFLNTTPKFILKPNVTT 571
Query: 514 TVE---DVDFIKTNANQAGIYVTSYSDDRWTTLSKQSDLLTV-------EDRTGLVADCK 563
TV+ + +I N Q G Y +YSDD W + L+T +R +V D
Sbjct: 572 TVQFNSTIKWIVVNIQQTGYYRVTYSDDNWHAI--HHALITANWGGIHENNRAQIVDDLF 629
Query: 564 TLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQ 623
L+ +GY + L +I + E +++ W N L + + + + +
Sbjct: 630 NLARAGYVTYNLTLDVIEYLQTETNYIPWTSAFNGFNYLTIRLGNDTAD----FNYYIQT 685
Query: 624 LVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIP 683
L ++ + LG+ + N++ L+ ++ F+ + +P
Sbjct: 686 LTNKAYNQLGFNEASNDTALDIYLRTKILSWACRYGSSDCISQAQGYFQSLAT-----VP 740
Query: 684 PLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLF 743
I+++V+ R+G ++ L+ +KN + + E+ G + +L+++ +
Sbjct: 741 KNIRATVYCVGLREGGEAEFQALYNKFKNETVATEETLLQNSFGCVKTQSLIEKVFDLII 800
Query: 744 DGTVLNQDIYIPMGGM-RGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGF 802
+ QD + + + E + ++A + ++ L + + + ++++ + F
Sbjct: 801 SDEIRRQDKSSVLATLYTENNENVSPVFALVTQKYEELAEAM-GGYSAVATVISNIAARF 859
Query: 803 TSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKAN 839
T+ Q + ++E+F K K T T K N
Sbjct: 860 TTNQQLTDLENFNKANGAKFGSSQATLTAAEATVKEN 896
Score = 213 bits (543), Expect = 8e-55
Identities = 175/637 (27%), Positives = 284/637 (44%), Gaps = 54/637 (8%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFK---FDGTVSIDLKV-NDKESDFVELNTFELDIHEAKIN 65
L +V P HY L + ++ + FDG VSI L+V E + L+ LDI E +
Sbjct: 980 LEGSVVPSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHADTLDITECWLL 1039
Query: 66 DVKSLETVTDEENQTSRFKFPAGT----------LKDSDNVTIDIKFTGILNDTMAGFYR 115
D + E SR + A T + N T+ K+TG + MAGF+
Sbjct: 1040 DAAGAQV---EAIDISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFFS 1096
Query: 116 AKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKK 175
A Y++ T T+++A TQM+ +AR PCFDEP LKA F++ +V ++N +K+
Sbjct: 1097 ASYVERDTNVTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKE 1156
Query: 176 EEIFDGKKFT-YFNPTPKMSTYLVAFIVAEL----EYVECKDFRIPVRVYATPGSEHLGQ 230
+ +F +F TP MSTYL+AF+VA E P T S H+GQ
Sbjct: 1157 TKALSQDRFVDHFKETPVMSTYLLAFMVANYSARGNESEFAVLTRPEFYDNTEFSYHVGQ 1216
Query: 231 YAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNAS 290
+ + F+ + E + + F MENWGL+ Y D+L+ E S
Sbjct: 1217 QVVSAYGE---LFQSPYA-ELGNDVLQYASSPRFPHNGMENWGLIIYS-DDVLIQEPGYS 1271
Query: 291 LERIKR--VAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWE 348
+ + ++ HE +H WFG+ VT WW WLNE FA + ++ +Q P++ + E
Sbjct: 1272 DDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDE 1331
Query: 349 QYVADDLQSALGLDSLRSSHPIEVPVKRADEINQI---FDHISYAKGSSLLRMISQWLGE 405
Q+V +Q G D+ + P+ P +QI F I+YAKG+ ++RM +G
Sbjct: 1332 QFVVRQMQLIFGTDAQNGTQPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGA 1391
Query: 406 DVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGK----DVRNVMDIWTKKVGFP--IVSV 459
+ F + YL ++ N +L+ L E K D+ + + +T++VG+P IV
Sbjct: 1392 ENFDTAIRSYLQQYHLTNTVPYNLFYHLFEHWPKNQDVDLVDFLTDYTEQVGYPMIIVKA 1451
Query: 460 TEDGHKITFKQNRYLNTADVKPEEDKTL-YPVFLSLKTNSGVDHSLTLDERELTVTV--- 515
+ +T +Q+R+L D + TL Y V ++ TN D + L TV
Sbjct: 1452 LQGNKVVTVEQSRFLLNKD--DGSNATLKYTVPITFTTNLERDFYNLTPYKYLHKTVNVL 1509
Query: 516 -----EDVDFIKTNANQAGIYVTSYSDDRWTTL-----SKQSDLLTVEDRTGLVADCKTL 565
+D+I N Q+ Y D L + + VE+R ++ D
Sbjct: 1510 WLDFTSPIDWILFNLRQSNYQRVFYDDTLREGLLLAISATNHSGIPVENRAQIIDDLFNF 1569
Query: 566 SLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSL 602
+ + Y + + + E +V W + +L ++
Sbjct: 1570 AQAQYVDYADVFRFLEYLAKEVEYVPWYAVYENLNTV 1606
>7301517 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1078
Score = 316 bits (810), Expect = 8e-86
Identities = 249/896 (27%), Positives = 397/896 (43%), Gaps = 66/896 (7%)
Query: 16 PLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFE---LDIHEAKINDVKSLET 72
PLHY L +EP T +G+++I++ E D ++ ++E LD+H I++V+ +
Sbjct: 180 PLHYSLLIEPSVATSISNGSLTIEI-----ERDVSKVTSWEPIVLDVHNVSISNVRVIRA 234
Query: 73 VTD-----EENQTSRFKFPAG--------------TLKDSDNVTIDIKFTGILNDTMAGF 113
+ D E Q F G ++ V + + F + DT+ G
Sbjct: 235 LADGASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVTDTLQGI 294
Query: 114 YRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTH-LSNMD 172
Y+ Y + T ++M +TQ P DARRAFPCFD P++KA+F I++V + LSNM
Sbjct: 295 YKTSYTNPDTKNEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMP 354
Query: 173 VKKEEIFD-GKKFTYFNPTPKMSTYLVAFIVAEL--EYVECKDFRIPVRV--YATPGSEH 227
F G F TPKM TYLVAFIV+ + + +D + RV + P
Sbjct: 355 KSGSRRFRRGFIRDDFETTPKMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVG 414
Query: 228 LGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEK 287
+ YA + K L ++E FGI+ LPK+D V+V +F AMENWGL+T+R LL+ E
Sbjct: 415 MTHYAYKMVRKFLPYYEDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPED 474
Query: 288 ---NASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEW 344
+S E ++ VA ++ HELAHQWFGNLVT WW+ LWL EGFA +MS+ A PE+
Sbjct: 475 LQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEF 534
Query: 345 KVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLG 404
+ + + + ++ D+ +SH I V+ +++ +IFD ISY+KG+ LLRM++ +G
Sbjct: 535 QSMDTLTMLEFKESMEHDADNTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVG 594
Query: 405 EDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGK--------DVRNVMDIWTKKVGFPI 456
+ F L KF +GN +DLW L+ + V+ +MD W + G+P+
Sbjct: 595 DVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPV 654
Query: 457 VSVTEDGHKITFKQNRYLNTADVKPEEDKTLYPVF-----LSLKTNSGVDHSLTLDEREL 511
V+V G + +Q RYL + ++ P+ L N + DE EL
Sbjct: 655 VNVERRGADLVLRQERYLLPSKNTADQSTWFIPITFETDELRKGDNIPTHWMRSEDEEEL 714
Query: 512 TV------TVEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQSDLLTVEDRTGLVADCKTL 565
V + + I N N+ G Y +Y W L K L R L+ D L
Sbjct: 715 IVGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSWLALKKNFSTLPRITRAQLLDDALHL 774
Query: 566 SLSGY-TSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQL 624
S + Y T L+ + D ++W L L EP E F + +
Sbjct: 775 SQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYLIYNLKREP--AYETFRAFMKFI 832
Query: 625 VSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKY-TSGDSNAIP 683
V G +NES+ + + + F ++ +N I
Sbjct: 833 VRPAFDHYGLHEPDNESHLQLKHRALVAYFACKFNYDRCTQKAQMKFREWMRDPKNNPIK 892
Query: 684 PLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLF 743
P +KS ++ T +G++ + + YK +S+ EK L LG P L+ + L
Sbjct: 893 PNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKPWLLSKYLNMTI 952
Query: 744 DGT--VLNQDIYIPMGGMR----GHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTV 797
+ T +L QD + + GH+ L KE + F M+ S+
Sbjct: 953 NPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMIKSLTIY 1012
Query: 798 ATSGFTSRQAIDEIEDFFKDKSTKGFDQSLAQTLDTITSKANWVDRDREVVVKFLK 853
+ Q +D + + + ++ L+ + + W + FL+
Sbjct: 1013 MNKDYHKHQLLD-LAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLE 1067
>7300768 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1878
Score = 293 bits (749), Expect = 1e-78
Identities = 202/619 (32%), Positives = 308/619 (49%), Gaps = 42/619 (6%)
Query: 6 DRIILPQNVSPLHYKLQLEPYFDTFK--FDGTVSIDLKVNDKESDFV----ELNTFELDI 59
D LP + P HY + L T F+GTV+I L V + + V +L F I
Sbjct: 980 DNYRLPYDTIPSHYAVSLSTNVHTGDTVFNGTVAITLSVLNTTTKIVVHARQLENFTASI 1039
Query: 60 HEAKINDVKSLETVTDEENQTSRFKFPAGTLKDSDNVT--IDIKFTGILNDTMAGFYRAK 117
+ + + + E V + E + F L ++ T + I + G L GFY +
Sbjct: 1040 IQQGVTEAVAQELVYEYEAEREFLTFSKTGLTFPEDTTWILTINYQGHLRTDNGGFYLST 1099
Query: 118 YIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEE 177
Y D G TKY+ATTQ E TDAR AFPC+DEP+ +A F IT+ DP +SNM V
Sbjct: 1100 YTDEE-GNTKYLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNMPVDSSS 1158
Query: 178 IFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAAN--- 234
T F T M +YLVAFIV+E + E + +P RV++ G+EH ++A
Sbjct: 1159 T---SGVTVFQKTVNMPSYLVAFIVSEFVFSEGELNGLPQRVFSRNGTEHEQEWALTTGM 1215
Query: 235 LTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERI 294
L K LS + F + + LPK+D + +F+AGAMENWGL TYR LL + +N++
Sbjct: 1216 LVEKRLSGY---FDVPFALPKLDQAGIPDFAAGAMENWGLATYREEYLLYNTENSTTSTQ 1272
Query: 295 KRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADD 354
+A + HE AH WFG+LV ++WW LWL EGFAT A + PEW +++ + A
Sbjct: 1273 TNIATIEAHEDAHMWFGDLVAIEWWSFLWLKEGFATLFENLAVDLAYPEWDIFQTFHAGS 1332
Query: 355 LQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQ 414
QSAL D+ ++ P+ V++ EI ++D +SYAK S+L M L VF +G+
Sbjct: 1333 YQSALVNDASANARPMSHFVQKPSEIALLYDSVSYAKAGSVLDMWRHALTNTVFQRGLHN 1392
Query: 415 YLNKFKFGNAKTEDLWDALSEASGKD-------VRNVMDIWTKKVGFPIVSVTE--DGHK 465
YL +F A L++A+++A+ ++ V ++M WT + G P+++VT D
Sbjct: 1393 YLVDNQFTAANPSKLFEAIAKAAVEENYEVKATVPDMMGSWTNQGGVPLLTVTRNYDNGS 1452
Query: 466 ITFKQNRYLNTADVKPEEDKTLY-PV-FLSLKT----NSGVDHSLTLDERELTV--TVED 517
T KQ+ Y N D DK Y P+ + K N+ H L L++ E+T+ ++
Sbjct: 1453 FTVKQSVYTNDKDY--TNDKLWYVPINYAESKNPDFRNTEATHYL-LNQSEITIYSDLDQ 1509
Query: 518 VDFIKTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVADCKTLSLSGYTST 573
+++ N G Y Y + + L + + +R L+ D + SG
Sbjct: 1510 TNWLILNKKSTGYYRVLYDAQNYQLITSALITRPHKIDPRNRAQLINDLYRFATSGRVPH 1569
Query: 574 KNFLQLISQWKNEDSFVVW 592
L+L++ ED + W
Sbjct: 1570 ATLLELLTYLPQEDQYSPW 1588
Score = 292 bits (747), Expect = 2e-78
Identities = 233/890 (26%), Positives = 403/890 (45%), Gaps = 61/890 (6%)
Query: 10 LPQNVSPLHYKLQL--EPYFDTFKFDGTVSIDLKVNDKESDFV----ELNTFELDIHEAK 63
LP P Y ++L + +F+GTV+ID++V ++ S+ + + FE I
Sbjct: 58 LPNTTEPESYNVELWTNVHNGDTEFNGTVNIDIRVLNETSNITLHYRQTSNFEATIISRD 117
Query: 64 INDVKSLETVTDEENQTSRFKFPAGTLKDS----DNVTIDIKFTGILNDTMAGFYRAKYI 119
+ ++ E Q T ++ N TI I +TGI M GFY + Y
Sbjct: 118 VATPTAIPLTVTPELQREFLVLTQTTAGEAFGANTNWTITINYTGIHRSDMGGFYISSYT 177
Query: 120 DNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF 179
D+ GE ++ATTQ E T+AR AFPC+DEP +A+F IT+ DP T +SNM V
Sbjct: 178 DD-DGEQHFLATTQFESTNARHAFPCYDEPARRANFTITIHHDPSYTAISNMPVNTAATS 236
Query: 180 DGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKT 239
G T F TPKMSTYLVAFIV++ E + I RV++ G + ++A
Sbjct: 237 SG--VTAFQTTPKMSTYLVAFIVSDFESTTGELNGIRQRVFSRKGKQDQQEWALWSGLLV 294
Query: 240 LSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAE 299
S FG+ + LPK+D + +FSAGAMENWGL TYR + +++N+++ +A
Sbjct: 295 ESSLASYFGVPFALPKLDQAGIPDFSAGAMENWGLATYREQYMWWNKQNSTINLKTNIAN 354
Query: 300 VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSAL 359
++ HE AH WFG+LV++ WW LWL EGFAT S+ + + P W ++ + +D SAL
Sbjct: 355 IIGHEYAHMWFGDLVSIKWWTYLWLKEGFATLFSYESNDIAFPLWDTYQIFHVNDYNSAL 414
Query: 360 GLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKF 419
D+L S+ P+ V+ EI+ ++ SYAK +S+L M + VF G+++YL K
Sbjct: 415 LNDALASAVPMTHYVQTPSEISNRYNTFSYAKPASVLYMFKNAWTDKVFRTGLNKYLTKN 474
Query: 420 KFGNAKTEDLWDALSEASGK-------DVRNVMDIWTKKVGFPIVSVTE--DGHKITFKQ 470
++ + DL+ + E++ + V ++ W+ + G+P+++VT + IT Q
Sbjct: 475 QYTSCDEWDLFASFQESADELGFTLPASVDDIFSSWSHQAGYPLLTVTRNYNAGTITITQ 534
Query: 471 NRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDV---------DFI 521
RY+ K + + + V L+ T + D+ T L E V D+I
Sbjct: 535 KRYVAN---KTDTNSATWYVPLNFATANKYDYRDTSATHYLLNVTETVISDVEASSDDWI 591
Query: 522 KTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFL 577
N +G Y T Y + L Q +R L+ D + S L
Sbjct: 592 IVNIQNSGYYRTLYDTQNYGLITAALKSQPWRFHPRNRAQLLYDTYIFVSTDRLSHSILL 651
Query: 578 QLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFS 637
+L+ NE + W N++ ++ + ++ +F ++L+ +G
Sbjct: 652 ELLGYLTNEQQYAPW-STANTILTVYDRY-LRGDDSYYNFQDFVKRLIDPIFDKIGVNEI 709
Query: 638 ENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARD 697
E Y + L++ + +Y + AI +K+ + R
Sbjct: 710 PGEHYLNNYLRIVLVSLACQVGSDDCYNQSANKLSEYLY-NGTAIEATLKTQAYCAGLRS 768
Query: 698 GNAKNYEKLFAIYKNPSSSDEK---LSALRCLGRFEDPALMKR-------TLGYLFDGTV 747
+ Y ++ + + S S ++ +S+L C G R +L Y ++
Sbjct: 769 TTNEIYSRVQSDLLSSSDSTDRSLFISSLGCSGSTSQLLDFLRLSLDTNNSLSYSERTSL 828
Query: 748 LNQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQ- 806
LN + G+ + + NW+A + + ++ +AT + +Q
Sbjct: 829 LN-------SAYSRSEIGLTASLEFLESNWEAYANLSDSAKPLDAALRGIATYVVSEKQK 881
Query: 807 -AIDEIEDFFKDKSTKGFDQSLAQTLDT-ITSKANWVDRDREVVVKFLKE 854
++ + D + + L+ T+D+ ITS W++ +R+ V+ ++++
Sbjct: 882 TRLNALVDVVEADGPSYINDDLSTTIDSRITSNFAWLEVNRDPVLNWIED 931
>CE24087 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 781
Score = 288 bits (738), Expect = 2e-77
Identities = 197/712 (27%), Positives = 344/712 (47%), Gaps = 33/712 (4%)
Query: 130 ATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVK-KEEIFDGKKFTYFN 188
A TQ EPT AR+ PCFDEPN KA+F++ ++ +P SNM++ +E +G F
Sbjct: 19 AATQFEPTFARKMLPCFDEPNFKATFQVAIIRNPHHIARSNMNILISKEYKNGLIKDVFE 78
Query: 189 PTPKMSTYLVAFIVAE-----LEYVECKDFRIPVRVYATPGSEHLGQ--YAANLTAKTLS 241
+ KMSTYL+A V + I VR+YA P GQ + + T + L
Sbjct: 79 KSVKMSTYLLAVAVLDGYGYIKRLTRNTQKAIEVRLYA-PQDMLTGQSEFGLDTTIRALE 137
Query: 242 FFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVV 301
FFE F I YPL K+D +A+ +FS GAMENWGLVT+R LL +E+ AS+ + +A ++
Sbjct: 138 FFEDYFNISYPLDKIDLLALDDFSEGAMENWGLVTFRDSALLFNERKASVVAKEHIALII 197
Query: 302 QHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGL 361
HE+AHQWFGNLVTMDWW ++LNEGFA +M + P+W + ++ A++L +
Sbjct: 198 CHEIAHQWFGNLVTMDWWNEVFLNEGFANYMEYKCVEHLFPDWSIMSRFYAENLAFSQEP 257
Query: 362 DSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKF 421
D SS IE D + +FD I+Y K ++++ MI++ G+ F + +YLNK+ +
Sbjct: 258 DGFLSSRAIE--SDDDDSLLNLFDAINYHKAAAIIHMIAEMAGQKNFQNALVEYLNKYAY 315
Query: 422 GNAKTEDLWDALSEASG----KDVRNVMDIWTKKVGFPIVSV--TEDGHKITFKQNRYLN 475
NA DLW + + + + ++ +T +VG+P+++V T++G + Q R+L
Sbjct: 316 SNAIGVDLWKIVEKHANLQGTVSIPDLAKAYTTQVGYPLLTVERTDEG-VLVHNQTRFLF 374
Query: 476 TADVKPEEDK--TLYPVFLSLKTNS---GVDHSLTLDERELTVTVEDVDFIKTNANQAGI 530
K EE + +P+ +S + + H + D++ +T D++ N G
Sbjct: 375 AEGDKAEEKRGDWKWPIPISYRDSEHRRKKQHWIQADDKNVTWETTSNDWLILNTGGVGY 434
Query: 531 YVTSYSDDRWTTLSKQ----SDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKNE 586
+ Y + + L KQ ++ DR+ ++ D LS + + + L+ + E
Sbjct: 435 FKVLYDPETYRKLVKQLQRNHTTISPIDRSMILVDSFDLSKTSLLNISVYFDLLEYVEKE 494
Query: 587 DSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVSEKTHSLGWEFSENESYASQR 646
+ W + L +++A E + L+ +F R L+ SL W+ + + +R
Sbjct: 495 TDKMTWSIVGKQLRTIEA--LIEESDYLDIYQDFQRSLIMRLYESLDWD-EQGANPNQKR 551
Query: 647 LKVEMFXXXXXXXXXXXXXXXXXMFEKYTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKL 706
L+V++F + ++ S S P + G +E++
Sbjct: 552 LQVDIFAVACRLQIKDCTKQAYQRYLQWVS--SGVRNPEHHMIALMEGVKQGETTAWERI 609
Query: 707 FAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMRGHKEGI 766
+ YK +S EK + + L +D +L+ R L Y DG + I ++
Sbjct: 610 WKAYKTATSPSEKNNIIGALTSTKDASLINRLLKYCLDGKIKANLIPRVFSYFSLNQSTR 669
Query: 767 KTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFKDK 818
+W + K +++ H +++ S + ++ ++E+++F K +
Sbjct: 670 NIVWKFFKTHFEQFHGILGKG-SLMASCVKCLAEPLSTETELEEVKEFLKSQ 720
>7301770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 814
Score = 284 bits (726), Expect = 5e-76
Identities = 168/430 (39%), Positives = 238/430 (55%), Gaps = 23/430 (5%)
Query: 6 DRIILPQNVSPLHYKLQLEPYF---DTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEA 62
D LP + P Y +++ D F F+GTV I ++V + + L++ +L I +
Sbjct: 23 DHFRLPTALRPQSYDVRILTQLENPDDFHFNGTVKIQIEVLQNTHN-ITLHSKDLTIDDT 81
Query: 63 KINDVKSLETVTDEENQTSRFKFPA------GTLKD---SDNVTIDIKFTGILNDTMAGF 113
+I + T E TS P T K+ + + F+ L D +AG+
Sbjct: 82 EITLSQIGGEETTENCITSTAVNPTHDFYILNTCKELLAGQFYELSLPFSAKLQDQLAGY 141
Query: 114 YRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDV 173
YR+ Y++ ET++++ TQ EP AR AFPCFDEP KASF ITL K T LSNM V
Sbjct: 142 YRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPV 201
Query: 174 KK---EEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIP----VRVYATPGSE 226
+ E +T F + MSTYLVA+ + + + K +P R +A P +
Sbjct: 202 NETRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSH---KPSTLPNGTLFRTWARPNAI 258
Query: 227 HLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDE 286
YAA L K L ++E+ FGI++PLPK+D +AV +FSAGAMENWGLVT+ LL
Sbjct: 259 DQCDYAAELGPKVLKYYEELFGIKFPLPKVDQIAVPDFSAGAMENWGLVTFAESTLLYSP 318
Query: 287 KNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKV 346
+ +S E + A +V HELAHQWFGNLVTM WW LWLNEGFAT+++ P+W+
Sbjct: 319 EYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRT 378
Query: 347 WEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGED 406
+ +L + DSL SSHPI P++ +I++ FD ISY KGSS++RM+ +LGE+
Sbjct: 379 LQLESMSNLLTIFRKDSLESSHPISRPIEMTSQISESFDEISYQKGSSVIRMMHLFLGEE 438
Query: 407 VFVKGVSQYL 416
F G+ L
Sbjct: 439 AFRTGLKLVL 448
Score = 62.8 bits (151), Expect = 2e-09
Identities = 65/341 (19%), Positives = 134/341 (39%), Gaps = 18/341 (5%)
Query: 531 YVTSYSDDRWTTL-----SKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKN 585
Y +Y W L S+ + V +R L+ D + +G + LQ+IS +
Sbjct: 475 YKVNYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLER 534
Query: 586 EDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFTRQLVS---EKTHSLGWEFSENESY 642
E + W+ ++L + P FTR+L++ E + + + E
Sbjct: 535 ERELLPWKSAFDNLQFVSGILRQTPN--FRFFKNFTRRLITPIYEHLNGINDTVASEEQQ 592
Query: 643 ASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTS----GDSNAIPPLIKSSVFGTVARDG 698
LK + + + S + N +P I+ V+ T + G
Sbjct: 593 DKTILKAIVADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHG 652
Query: 699 NAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRTLGYLFDGT--VLNQDIYIPM 756
++++ L+ Y+ + + EK L LG ++ +++R L FDG + QD
Sbjct: 653 CDEDWDFLWTRYQKANVATEKQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVF 712
Query: 757 GGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFK 816
+ + G + +N D++ K + P + +L + +++ DE +F
Sbjct: 713 QAIADSEVGFLLAKKYLMDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMA 772
Query: 817 DKST--KGFDQSLAQTLDTITSKANWVDRDREVVVKFLKEH 855
K +Q+++Q+L+T+ W +R+ E + + +H
Sbjct: 773 SSKDQLKDIEQTISQSLETMLINVQWKERNYERFTRAISKH 813
>7300767 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 988
Score = 280 bits (716), Expect = 7e-75
Identities = 188/667 (28%), Positives = 314/667 (46%), Gaps = 53/667 (7%)
Query: 1 MSSQPDRIILPQNVSPLHYKLQLEP--YFDTFKFDGTVSIDLKVNDKESDFV----ELNT 54
M + + LP PL Y+L + + F G +ID+ + ++ V L
Sbjct: 22 MGERERSLRLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTD 81
Query: 55 FELDIHEAKINDVKSLETVTDEENQTSRFKF-----PAGTLKDSDNVTIDIKFTGILNDT 109
++ +H + ++ +T + T+ ++ ++I +T I+
Sbjct: 82 IQITVHRLMAEGSEIVDDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLEILYTAIMASR 141
Query: 110 MAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLS 169
AG Y Y D T Y+A TQ EPT R FPC+DEP K++F I + + +S
Sbjct: 142 PAGLYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSSHSAIS 201
Query: 170 NMDVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLG 229
NM VK+ K T F+ TP +STYLVAF++++ + I +Y +P S+ G
Sbjct: 202 NMPVKEVLAHGDLKTTSFHTTPPISTYLVAFVISDFGSISETYRGITQSIYTSPTSKEKG 261
Query: 230 QYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNA 289
Q A +T++ E FG+ YPLPK+D VA+ + AMENWGL+TY+ V+LL KN
Sbjct: 262 QVALKNAVRTVAALEDYFGVSYPLPKLDHVALKKNYGAAMENWGLITYKDVNLL---KNI 318
Query: 290 SLERIKRVAEVV--QHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVW 347
S + KR +++ HE+AHQWFGNLV+ +WW W+NEGFAT+ S+ + P K+
Sbjct: 319 SSDGQKRKLDLITQNHEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMM 378
Query: 348 EQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDV 407
+ ++ + SA +S HP+ V+ +I +FD ISY +G+ +++M + +
Sbjct: 379 DMFMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFRQKL 438
Query: 408 FVKGVSQYLNKFKFGNAKTEDLWDALSEASGKD-----------VRNVMDIWTKKVGFPI 456
FV+G+S +L K+++ A +L+DAL D +R +M WT PI
Sbjct: 439 FVRGISHFLEKYRYSVANELNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPI 498
Query: 457 VSVTE--DGHKITFKQNRY----------LNTADVK-PEEDKTLYPVFLSLKTNSGVDHS 503
+ VT + + ITF Q +N A + P + T +F+ +
Sbjct: 499 LVVTRNYENNTITFTQRSVHMKDELWWIPINFATTQSPNFEDTQVDMFMPPQP------Q 552
Query: 504 LTLDERELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQ----SDLLTVEDRTGLV 559
T+ +L + V D+I N G Y+ Y D +++Q ++ +R GL
Sbjct: 553 YTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYDTDNLMAIARQLQTNHSVIHPINRLGLF 612
Query: 560 ADCKTL-SLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALD 618
D L + + +L+ + E+ + W Q+ +++ L ++L +
Sbjct: 613 RDLGPLIEHNEIEQVEVVFELLKYLELEEDVLTWNQLQDTIECLTRNLHGTSSQSL--FN 670
Query: 619 EFTRQLV 625
EF R+LV
Sbjct: 671 EFVRRLV 677
>CE20255 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1045
Score = 240 bits (613), Expect = 6e-63
Identities = 149/419 (35%), Positives = 219/419 (51%), Gaps = 30/419 (7%)
Query: 95 NVTIDIKFTGILNDTMA-GFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKA 153
N T+D+ F +N +A G + A Y ET+Y+ TQ++ ++AR FPC D P++KA
Sbjct: 250 NYTLDVAFKSAINLNLAYGLFAAPY--TFENETRYVVATQLQISEARTVFPCIDVPDMKA 307
Query: 154 SFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDF 213
F+ ++ T ++NM ++ T F+ TP MSTYL AF V++ Y+E
Sbjct: 308 QFDTVIIHPTGTTSIANMMENSTKVDGEWTTTTFHRTPPMSTYLFAFSVSDYPYLETFSG 367
Query: 214 R-IPVRVYATPGSEHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENW 272
R + RVY P Q L F+E FGI YPL K+D V V S AMENW
Sbjct: 368 RGVRSRVYCDPTKLVDAQLITKSIGPVLDFYEDYFGIPYPLEKLDVVIVPALSVTAMENW 427
Query: 273 GLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWM 332
GL+T R + L E ++ + V E+V HELAHQWFGNLVTM WW LWLNEGFAT +
Sbjct: 428 GLITIRQTNGLYTEGRFAISQKHDVQEIVAHELAHQWFGNLVTMKWWNDLWLNEGFATLI 487
Query: 333 SWYACNQFQPEWKVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDH------ 386
S A + + +E A+ AL D + S P+ + + N FD
Sbjct: 488 SVRAVDFLENTTWRYEDSSAESQCVALRADQIDSISPV------SGKKNSNFDSYMEIQG 541
Query: 387 --ISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDAL-----SEASGK 439
I Y K + ++RMI + + ED+F +G+ ++LN F + NA EDL++ L S A G
Sbjct: 542 KAIIYKKSAIIIRMIERLVEEDIFRQGLKRFLNTFLYKNADHEDLFNVLVYVHDSSAGGH 601
Query: 440 ------DVRNVMDIWTKKVGFPIVSVT-EDGHKITFKQNRYLNTADVKPEEDKTLYPVF 491
+ +VMD W ++ FP++ V ++G +T +Q +Y + +PE+ P+F
Sbjct: 602 LRGQNFSLSDVMDTWIRQAHFPVIHVNRKEGSLVTLRQEKYEHVPRDEPEKQVWKIPIF 660
>CE26001 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1815
Score = 237 bits (605), Expect = 5e-62
Identities = 167/506 (33%), Positives = 244/506 (48%), Gaps = 47/506 (9%)
Query: 10 LPQNVSPLHYKLQLEPYFDT----------FKFDGTVSIDLKVNDKESDFVELNTFELDI 59
LP N+ + Y L +PYF + F FDG SI ++ F+ LN + I
Sbjct: 81 LPPNLYAIDYSLWFQPYFPSPGVQYAPEKNFTFDGRASIQVEALVASDRFI-LNAYNFKI 139
Query: 60 HEAKINDVKS----LETVT-DEENQTSRFKFPAGTLKDSDNVTIDIKFTGILND-TMAGF 113
K+ D+ + +++ D+ Q A + I+ +TGI+N T G
Sbjct: 140 QSYKVVDIDGTVVPINSISQDDTTQQLSLITNANGVVAGQIYNIEFVYTGIINPYTDGGV 199
Query: 114 YRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDV 173
Y Y D G T YM T MEP AR+ FP DEP+ KA F IT+ LSNM
Sbjct: 200 YYTSYND-PQGNTHYMIATHMEPFSARKVFPSLDEPSYKAKFTITVQYPASQVALSNMME 258
Query: 174 KKEEIFDGKKFTY-FNPTPKMSTYLVAFIVAEL---EYVECKDFRIPVRVYATPGSEHLG 229
+ D T F TPKMS+YL+AF V +YV R + PG+E
Sbjct: 259 TEPTKIDNIWSTITFPQTPKMSSYLIAFAVGPYVNSQYVN--KHNTLTRAWGWPGTEQYL 316
Query: 230 QYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNA 289
Q+AA + L + GI++PL K D + + EF AGAMENWGL+ Y+ + +
Sbjct: 317 QFAAQNAGECLYQLGEYTGIKFPLSKADQLGMPEFLAGAMENWGLIIYKYQYIAYNPTTM 376
Query: 290 SLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVW-- 347
+ ++ A+V+ HELAHQWFG+LVT WW+ L+LNEGFA + + P+ +
Sbjct: 377 TTRNMEAAAKVMCHELAHQWFGDLVTTAWWDDLFLNEGFADYFMTFIQKSVYPQQATYLD 436
Query: 348 EQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDV 407
V D+LQ L D +HP+ P A FD I+Y KG+S+LRM+S LG DV
Sbjct: 437 TLQVLDELQVGLTADVRYDAHPLVYPDGPA------FDDITYNKGASMLRMLSDVLGADV 490
Query: 408 FVKGVSQYLNKFKFGNAKTEDLWDALSEASGK-----------DVRNVMDIWTKKVGFPI 456
F +G+ YL K ++ NA DL+ L++ + +V + M + + P+
Sbjct: 491 FKQGIRAYLQKMQYSNANDFDLFSTLTDTAKSNNILDWCGLPLNVTDFMQPYIHQTNHPL 550
Query: 457 VSVTEDGHKI---TFKQNRYLNTADV 479
+ + KI TF Q +L+ +D+
Sbjct: 551 IRY-NNNQKIGGSTFSQEPFLDISDL 575
Score = 209 bits (531), Expect = 2e-53
Identities = 162/573 (28%), Positives = 264/573 (45%), Gaps = 39/573 (6%)
Query: 100 IKFTG-ILNDTMAGFYRAKYIDNATGETKYMATTQMEP-TDARRAFPCFDEPNLKASFEI 157
I++TG I + G Y+ ++ TT E AR PC+DEP+ K FE+
Sbjct: 1107 IEYTGFIFQNPDEGDASNTYLGGLNNRKGWIFTTDFEGGPGARSLLPCWDEPSYKGQFEV 1166
Query: 158 TLVSDPKLTHLSN-MDVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-I 215
++ + LSN +D+++ +G T F T +MSTYL+A V + +
Sbjct: 1167 SVFHPTDMIALSNEVDIQRTIYDNGWTTTKFATTNQMSTYLLALCVGHFSNLATVTRTGV 1226
Query: 216 PVRVYATPGSEHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFS--AGAMENWG 273
RV+ G E G++A N+TA T+ F E F ++PL K+D +A+ E++ AGAMENWG
Sbjct: 1227 LTRVWTWSGMEQYGEFALNVTAGTIDFMENYFSYDFPLKKLDVMALPEYTMNAGAMENWG 1286
Query: 274 LVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMS 333
L+ + D A+ I VAE HE+ HQWFG++VT+DWW ++LNEGFA +
Sbjct: 1287 LIIGEYSLFMFDPDYATTRDITEVAETTAHEVVHQWFGDIVTLDWWNDIFLNEGFAQY-- 1344
Query: 334 WYACNQFQPEWKVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGS 393
W+A N + Y D + + +L+ V + +F Y KGS
Sbjct: 1345 WFA-NGIDNTFPEQHAYSIDYNRFYMNHIALKYDCIPGVAKPVISDTPPVFGIEPYYKGS 1403
Query: 394 SLLRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGK-----------DVR 442
+LL +++ L VF +G+S YL ++ + NA +LW +L+ A+ + DV
Sbjct: 1404 ALLNLLNNVLTPAVFQEGLSSYLTQYGYVNASPRNLWTSLTVAAQRHNITDWNGQPLDVS 1463
Query: 443 NVMDIWTKKVGFPIVSVTEDGHKITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDH 502
+ MD +T + +PI+++T G T + N+ D+TL+ V L +T +D
Sbjct: 1464 SFMDPYTLQTSYPIITLTLRGTS-TVQANQQ------SCMSDETLWNVPLFTQTPGALDF 1516
Query: 503 ----SLTLDERELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQ--SDLLTVED-- 554
+ T + + NA +Y D W ++ Q S++ T+
Sbjct: 1517 NWFVNFTGGNDATWLRPLPTGYRVDNAGSTSFARINYDDKSWYSIQAQLLSNMNTMSSTT 1576
Query: 555 RTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETL 614
R L+ D SG FL L NEDS WEQ I + + ++P+ +
Sbjct: 1577 RAMLLDDANFFYQSGRWEMTKFLDLTLYLVNEDSLAPWEQAIEFFTEMLNRFQYQPE--I 1634
Query: 615 EALDEFTRQLVSEKTHSLGWEFSENESYASQRL 647
+ + + Q+ W + N +A+ R+
Sbjct: 1635 DTVRNYVIQITKNAVSKFQW--NTNGLWANDRI 1665
>CE18904 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 786
Score = 237 bits (604), Expect = 7e-62
Identities = 176/608 (28%), Positives = 292/608 (47%), Gaps = 47/608 (7%)
Query: 10 LPQNVSPLHYKLQLEPYFDTFKFD---------GTVSIDLKVNDKESDFVELNTFELDIH 60
LP+NV P Y+L + + +K++ G V I ++V + E+D + L+T L+I+
Sbjct: 32 LPRNVFPTEYRLHITTFLPGYKWEADEKSFTFIGDVKIQIEVKE-ETDTIVLHTDSLNIN 90
Query: 61 EAKINDVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKF---TGILNDTMAGFYRAK 117
+++ + +N F+ ++ G + + G+YR
Sbjct: 91 NVLLHNACVCANL---KNLIQYFRLAITKFENRQQTNSKYSLYGKIGKIREDGEGYYRT- 146
Query: 118 YIDNATGETK-YMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNM-DVKK 175
I ET Y A TQ EPT AR PCFDEP KA + +T+V T LSN ++
Sbjct: 147 -ISPGLNETTMYNAVTQFEPTAARFMVPCFDEPEFKAIWHVTVVHPTGSTALSNAKEIDN 205
Query: 176 EEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGSEHLGQYAAN 234
+ D T F T KMS+Y++A V ++++ E + +RVY+ PG +A N
Sbjct: 206 TKTNDDFSTTEFESTLKMSSYILAIFVGDVQFKEAVTKNGVRIRVYSDPGHIDSVDHALN 265
Query: 235 LTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERI 294
++ L FEK FG Y + K+D +AV+ F GAMENWGL+ ++ L+ +N
Sbjct: 266 VSRIVLEGFEKQFGYPYEMDKLDLIAVYNFRYGAMENWGLIVHQAYTLI---ENLMPGNT 322
Query: 295 KRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADD 354
++EVV HE+AHQWFGNLVTM +W+ LWLNEGFAT+M+ Y P + Y++
Sbjct: 323 DIISEVVAHEIAHQWFGNLVTMKFWDQLWLNEGFATYMTAYGYTFLDPNYDRDYYYLSPQ 382
Query: 355 LQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQ 414
+S G + + I++ +Q +YAKG S +RM+ + +G + F + +
Sbjct: 383 FESQSGNELGPLNSMIKLSHGAIGNPSQ-----NYAKGCSFIRMLEKIVGTEHFNEAIRT 437
Query: 415 YLNKFKFGNAKTEDLWDALS------EASGK--DVRNVMDIWTKKVGFPIVSVTE---DG 463
YL+ F N + ++L+DAL E +GK D+ WT + G+P V V+
Sbjct: 438 YLHTHDFSNVEDKNLYDALRVYSDKLEINGKPFDIEEFGRCWTHQTGYPTVYVSSYYAGQ 497
Query: 464 HKITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHS-LTLDERELTVTVEDVDFIK 522
+++ + + + T D +K P++ ++ V+ + L D+ EL + F
Sbjct: 498 TRLSQVKVKEIVTGDFHECNNKWDIPIWYQQSGSTEVELTWLEKDQDELEINT--TGFAI 555
Query: 523 TNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQ 578
NAN G+Y YS+ + + L + + + + +++D G S KN L
Sbjct: 556 INANSNGLYDVVYSEVLYEQVASELKNNTQMYSASTKARVLSDAIHYYYKGEVSLKNSLI 615
Query: 579 LISQWKNE 586
+ N+
Sbjct: 616 IAQALAND 623
>7291179 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 931
Score = 227 bits (579), Expect = 5e-59
Identities = 185/686 (26%), Positives = 309/686 (44%), Gaps = 69/686 (10%)
Query: 10 LPQNVSPLHYKLQL-----EPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAK- 63
LP+ + PL Y++ + +PY F GTV IDL+ +++ + + LN +L I + +
Sbjct: 26 LPKWLVPLSYRVDIVTRINQPYQP---FGGTVVIDLR-SERSTKRIVLNAHDLAIGKRRA 81
Query: 64 --IND-------VKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFY 114
++D V S++ T K P LK + ++ + FT +L + GFY
Sbjct: 82 VTLSDKNGNSVPVSSIQMDIKLSRLTVSLKRP---LKVNVTYSMRVAFTSVLRNDNTGFY 138
Query: 115 RAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVK 174
+ Y+D+ T T+++A TQ EP AR AFPCFD+P + F+I L LSNM V+
Sbjct: 139 SSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQ 198
Query: 175 KEEIFDGKK---FTYFNPTPKMSTYLVAFIVAELE---YVECKDFRIPVRVYATPGSEHL 228
+ K +T F + M TYLVAF++++ + + + P+ +A P +
Sbjct: 199 RTIRHASLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQ 258
Query: 229 GQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKN 288
++A + A LSF+E F Y K+D VA+ +F+ + ENWGL + LL D +
Sbjct: 259 TEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQR 318
Query: 289 ASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWE 348
+S++ + VA V + +QWFGNLV++ WW +WL FA ++S + + +PEW E
Sbjct: 319 SSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQE 378
Query: 349 QYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVF 408
++ S L D+ ++ + V I ++ I K + L M+ + +GE+ +
Sbjct: 379 RHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAW 438
Query: 409 VKGVSQYLNKFKFGNAKTEDLWDALS--------EASGKDVRNVMDIWTKKVGFPIVSVT 460
+ + +YL + A + D WD L G ++ +M W + G+P+V+VT
Sbjct: 439 LTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVT 498
Query: 461 E--DGHKITFKQNRYLNTADVKPEEDKT-LYPVFLSLKTNSGVDHSLTLDERELT----- 512
D Q R+ T + + + V LS S + R LT
Sbjct: 499 RNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSK 558
Query: 513 ------------VTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSK------QSDLLTVED 554
+ E D+I N + +Y W L+K + L+ +
Sbjct: 559 PSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVN 618
Query: 555 RTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVW-------EQMINSLGSLKAAWA 607
R LV D +L+ SG L ++ ++ED FVVW E++ N S
Sbjct: 619 RAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLI 678
Query: 608 FEPKETLEALDEFTRQLVSEKTHSLG 633
F+ L +F R + S+ T S G
Sbjct: 679 FKTYMRLLLERQFKRVISSDLTSSSG 704
>CE18905 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 747
Score = 225 bits (573), Expect = 3e-58
Identities = 167/564 (29%), Positives = 269/564 (47%), Gaps = 49/564 (8%)
Query: 10 LPQNVSPLHYKLQLEPYFDTF---------KFDGTVSIDLKVNDKESDFVELNTFELDIH 60
LP++VSP HY + ++ Y + F+G V+I L + + +D + L++ L+I
Sbjct: 32 LPRHVSPSHYDIHIKTYLPGYGWKADENKITFEGNVNILLDIKET-TDKLVLHSSSLNII 90
Query: 61 EAKINDVKSLETVTDEENQT-SRFK--FPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAK 117
A + +++ QT S+F + T+K + I I F G + G +
Sbjct: 91 SATFQSDEQNVSISHWNVQTESQFLTFYLNNTVKVQSSAGIQINFQGKVRTDGLGLFAT- 149
Query: 118 YIDNATGETKYMAT---TQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVK 174
N+T E + T TQ E AR PCFDEP KA++ ++L T LSN
Sbjct: 150 ---NSTREDGTVMTNFATQFETIFARNMIPCFDEPEFKATWNVSLEHPTGSTALSNGIEV 206
Query: 175 KEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVEC-KDFRIPVRVYATPGSEHLGQYAA 233
+ ++ D K T + T KMS+Y++A + ++++ E + + +RVY P + +A
Sbjct: 207 ESKVNDDWKTTTYKKTLKMSSYILALFIGDIQFKETILNNGVRIRVYTDPVNIDRVDHAL 266
Query: 234 NLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLER 293
N++ L FE+ FGI YP+ K+D V+V F GAMENWGLV + L+ D +
Sbjct: 267 NISRIVLEGFERQFGIRYPMEKLDFVSVQNFKFGAMENWGLVIHNAYSLIGDPMD----- 321
Query: 294 IKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVAD 353
V E+V HE+AHQWFGNLVTM +W+ +WLNEGFA++M+ Y P+++ Y+
Sbjct: 322 ---VTEIVIHEIAHQWFGNLVTMKYWDHIWLNEGFASYMTSYGLTFLDPDYQRDTFYLNC 378
Query: 354 DLQSAL--GLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKG 411
+ G SL + + A + Y KG S +RM+ G + F +
Sbjct: 379 QFNPQINDGGVSLNFGKNLSSVMNNAATV--------YMKGCSFVRMLENIFGTEYFNEA 430
Query: 412 VSQYLNKFKFGNAKTEDLWDALSEAS------GK--DVRNVMDIWTKKVGFPIVSVTEDG 463
+ YL K ++ N DL++A +S GK D+ WT + GFP + V+ D
Sbjct: 431 IKFYLEKNQYDNVDDNDLYEAFRTSSETLDTNGKPFDIEKFARCWTHQNGFPTIQVSNDN 490
Query: 464 HKITFKQNRYLNTADVKPEED-KTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIK 522
T Q+ + E D K P++ + V + L+ ++ + D +
Sbjct: 491 GIATLTQSHLYEPQLMLNECDYKWDIPIWYQEPGEARVQMA-WLNRNSTSLELVADDSVI 549
Query: 523 TNANQAGIYVTSYSDDRWTTLSKQ 546
NAN G Y YSD + +++Q
Sbjct: 550 INANSIGYYEVLYSDKMYEKIAEQ 573
>YIL137c [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 946
Score = 196 bits (499), Expect = 1e-49
Identities = 213/882 (24%), Positives = 363/882 (41%), Gaps = 105/882 (11%)
Query: 10 LPQNVSPLHYKLQLE--PYFDTFKFDGTVSIDLKVNDK-------ESDFVELNTFELDI- 59
L V P HY+L+LE P + F G+ I LK N E F + D+
Sbjct: 8 LENPVVPSHYELRLEIDPKQSSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLI 67
Query: 60 ---HEAKINDVK-SLETVTDEENQTSRFKFPAGTLKDSD-NVTIDIKFTGILNDTMA--- 111
A I K L+ D S F + +D + + +++ G + D
Sbjct: 68 VLSAHATIGSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKTHHD 127
Query: 112 ---GFYRAKYIDNATGETK-YMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTH 167
G ++ ++D TG ++ T +P A FPC DEP+ K++F++ + +D +
Sbjct: 128 KTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKA 187
Query: 168 LSNMDVKKEEIFDG--KKFTYFNPTPKMSTYLVAFIVAELEYVECK-----DFRIPVRVY 220
+SN V+ E D K F TP M+T + F + +LE+++ + D IPV +Y
Sbjct: 188 VSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIPVSIY 247
Query: 221 ATPGSEHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVV 280
A P + + K L E F YPLPK+D V + S AMEN+G++T ++
Sbjct: 248 A-PWDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLN 306
Query: 281 DLLLDEKNASLERIKRVAE-VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQ 339
LL+ + E ++ A+ ++ HEL HQW GN ++ D WE LW NE FATW++ + Q
Sbjct: 307 HLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQ 366
Query: 340 FQPEWKVW--EQYVADDLQSALGLDSL----RSSHPIEVPVKRAD-EINQIFDHISYAKG 392
W E Y+ ++ + D+ RS I D + + IFD +Y KG
Sbjct: 367 NGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKG 426
Query: 393 SSLLRMISQWLGEDVFVKGVSQYLNKFKFGNA---KTEDLWDALSE-ASGKDVRNVMDIW 448
+LR + GE KG+ K +A K D+W+ + + +++ N + W
Sbjct: 427 IIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLKSQNITNFVSSW 486
Query: 449 TKKVGFPIVSV---TEDGHKIT-FKQNRYLN--TADVKPEEDKTLY--PVFLSLKTNSGV 500
T+ G P+V V +DG T Q+R++N + + K + + Y P+F L
Sbjct: 487 TRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGKMD 546
Query: 501 DHSLTLDERELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQSDLLTVEDRTGLVA 560
++ L +R L D + N G Y SY + L +D +T E + +
Sbjct: 547 TKNVLLTDRTLKF---DYPILVINHLAQGYYRVSYESEECYALI--NDKITEETLSEIDL 601
Query: 561 DCKTLSLSGYTSTKNF------------LQLISQWKNEDSFVVWEQMINSLGSLKAAWAF 608
L LS + + F L I+ + + W+ + L L+
Sbjct: 602 RKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQT--ID 659
Query: 609 EPKETLEALDEF-TRQLVSEKTHSLGWEFSE-NESYASQRLKVEMFXXXXXXXXXXXXXX 666
T L F +++V + + W E ++S LKV
Sbjct: 660 RASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAEL 719
Query: 667 XXXMFEKYTSGDSNAIPPLIKSSVFGTVARD-GNAKNYEKLFAIYKNPS----------- 714
F+ G +++P + +S+ V++ N K ++K+F + K S
Sbjct: 720 CQIYFKHLLQGPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINM 779
Query: 715 ----SSDEKL----SALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMR-GHKEG 765
SS+ + A+ LG D ++K+TL ++ + ++ + + + G K+
Sbjct: 780 YDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFI-TSNIESEGMELALFGFNYNFKKR 838
Query: 766 I------------KTLWAWTKENWDALHKKFPPSLTMLGSIL 795
+ +T+W W N+D +K T G L
Sbjct: 839 LNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHL 880
>7291558 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 844
Score = 192 bits (488), Expect = 2e-48
Identities = 129/440 (29%), Positives = 204/440 (46%), Gaps = 29/440 (6%)
Query: 194 STYLVAFIVAELEYVECKDFRIPVRVYATPGSEH--LGQ--YAANLTAKTLSFFEKAFGI 249
STYLVAF V +LE ++ + RV + LGQ + + K LSF+E F I
Sbjct: 155 STYLVAFAVHDLENAATEESKTSNRVIFRNWMQPKLLGQEMISMEIAPKLLSFYENLFQI 214
Query: 250 EYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQW 309
+PL K+D + V AMENWGLVTY L ++ + ++ A V HE AHQW
Sbjct: 215 NFPLAKVDQLTVPTHRFTAMENWGLVTYNEERLPQNQGDYPQKQKDSTAFTVAHEYAHQW 274
Query: 310 FGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSALGLDSLRSSHP 369
FGNLVTM+WW LWL EG +T+ + A + QPEW+ E++++ DL + DS +
Sbjct: 275 FGNLVTMNWWNDLWLKEGPSTYFGYLALDSLQPEWRRGERFISRDLANFFSKDSNATVPA 334
Query: 370 IEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDL 429
I VK E+ F Y KGS +RM+ + +GE+ F G+ +L +F FGN DL
Sbjct: 335 ISKDVKNPAEVLGQFTEYVYEKGSLTIRMLHKLVGEEAFFHGIRSFLERFSFGNVAQADL 394
Query: 430 WDALSEASGK--------DVRNVMDIWTKKVGFPIVSVTED--GHKITFKQNRYLNTADV 479
W++L A+ K ++ MD WT + G+P+V++ + ++T Q+R+ +
Sbjct: 395 WNSLQMAALKNQVISSDFNLSRAMDSWTLQGGYPLVTLIRNYKTGEVTLNQSRFFQEHGI 454
Query: 480 KPEED---------KTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTNANQAGI 530
+ + P F ++ L +L + +++ N A I
Sbjct: 455 EKASSCWWVPLRFVRQNLPDFNQTTPQFWLECPLNTKVLKLPDHLSTDEWVILNPQVATI 514
Query: 531 YVTSYSDDRWTTL------SKQSDLLTVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWK 584
+ +Y + W + S + ++ L+ D L+ L+ K
Sbjct: 515 FRVNYDEHNWRLIIESLRNDPNSGGIHKLNKAQLLDDLMALAAVRLHKYDKAFDLLEYLK 574
Query: 585 NEDSFVVWEQMINSLGSLKA 604
E F+ W++ I L L A
Sbjct: 575 KEQDFLPWQRAIGILNRLGA 594
>CE27507 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1073
Score = 184 bits (466), Expect = 7e-46
Identities = 154/497 (30%), Positives = 229/497 (45%), Gaps = 55/497 (11%)
Query: 10 LPQNVSPLHYKLQLE-PYFDTFKF-DGTVSIDLKVNDKESDFVELNTFELDIHEAKINDV 67
LP + P HY LQL+ FDT F +SI L+ ++ E+ H +
Sbjct: 125 LPLYILPYHYDLQLDFSQFDTHLFIRANISIHLESYGNSTED------EIQFHLGPNIKM 178
Query: 68 KSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNAT---- 123
+ + D + KF A T K ++ + + + G Y + N T
Sbjct: 179 ERMRLRKDGK------KFYAKTFKREESKKLGR--ISLRDPLQKGKYILEMTYNMTICDE 230
Query: 124 ---GETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNM------DVK 174
G T + TT+ EPT AR FPC+DEP +KA+F I++ + K T LSNM D K
Sbjct: 231 DVDGATSF--TTKFEPTLARAFFPCWDEPGVKATFNISVRHNKKYTVLSNMPPVESHDHK 288
Query: 175 KEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFR-IPVRVYATPGSEHLGQYAA 233
E D K T F TP MSTYL+AF + E +E + R IPV V+ P ++
Sbjct: 289 SWE--DQFKTTVFQTTPPMSTYLLAFAIGEFVKLESRTERGIPVTVWTYPEDVMSMKFTL 346
Query: 234 NLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDL-----LLDEKN 288
E A I YPLPK+D +A F G MENWGLV + + + D N
Sbjct: 347 EYAPVIFDRLEDALEIPYPLPKVDLIAARNFHVGGMENWGLVVFEFASIAYTPPITDHVN 406
Query: 289 ASLERIK---RVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWK 345
+++R+ R+ +++ HE AHQWFGNLVTM W L+LNEGFAT +Y E
Sbjct: 407 ETVDRMYNEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNEGFAT---FYVYEMMSTERP 463
Query: 346 VWEQYVADDLQSALGLDSLRSSHPIEVPVKRADE--INQIFDHIS-YAKGSSLLRMISQW 402
V Q+ D ++L L H + + + A E + F + Y KG L+RM+
Sbjct: 464 VTAQFEYYDSLASLILAQSEEDHRLSLVRELATESQVESSFHPTNLYTKGCVLIRMLRDL 523
Query: 403 LGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSE-----ASGKDVRNVMDIWTKKVGFPIV 457
+ + F V +YL K + + +DL+ +L A + + +V++ W G P +
Sbjct: 524 VSDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGAEQEKLSHVLEGWFVNEGIPEI 583
Query: 458 SVTE--DGHKITFKQNR 472
++ D +T Q +
Sbjct: 584 TLIRNYDNEMMTISQRK 600
>7291178 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 911
Score = 174 bits (442), Expect = 4e-43
Identities = 191/888 (21%), Positives = 352/888 (39%), Gaps = 81/888 (9%)
Query: 13 NVSPLHYKLQL----EPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKINDVK 68
N+ PLHY L L EP + F G V I L+V + E T L + ++ +
Sbjct: 26 NLRPLHYNLSLLTEVEPLKLSGNFSGEVIIRLRV------WRETRTIILSNNGLQVGENV 79
Query: 69 SLETVTDEENQTSRFKFPAGTLKD-----------SDNVTIDIKFTGILNDTMAGFYRAK 117
L T R + A ++ + T+ ++F+G L+ +G++
Sbjct: 80 LLVRRNTGGRVTVRKMWQASSVHQLGIVFNSMLWLGEEYTLVVQFSGQLSRA-SGYFVGG 138
Query: 118 YIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKK-- 175
Y+D+ +++A TQ+ P A FPCF+ A F + L +SNM V K
Sbjct: 139 YMDSKH-HPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKTS 197
Query: 176 EEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIP----VRVYATPGSEHLGQY 231
+ D +T F TP MS +AF + + IP + + P G Y
Sbjct: 198 DHEKDDYVWTTFQQTPAMSVQKLAFSINR--FTNRTSAEIPKGPALTTWLRPKIADQGDY 255
Query: 232 AANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASL 291
A ++T + + FF FG YP K+D + + + + + E+ GLV+Y L + ++
Sbjct: 256 AISITPQIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTT 315
Query: 292 ERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYV 351
++VA V E AH W +L + WL+ G + ++S +A + +P W+ E +
Sbjct: 316 RAKQQVASHVAQEFAHHWLSDLENAALY---WLHNGLSDYVSGFAVDNVEPAWRFHELSM 372
Query: 352 ADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKG 411
+ L DS S++P+ + Q + K + L RM+ +G F+
Sbjct: 373 VRQALAVLVEDSKSSAYPMSLAYASKSSDTQ-----ANQKSALLFRMLHSLIGTQAFLNA 427
Query: 412 VSQYLNKFKFGNAKTED-LWDALSEASGKD--------VRNVMDIWTKKVGFPIVSVTE- 461
+ YL + G++ + LW L E S V +MD WT + G+P++ V
Sbjct: 428 LRLYLQRSHKGSSSNQAFLWHTLQEESDNQMSLRQDIKVSQLMDSWTMQPGYPLIRVVRN 487
Query: 462 -DGHKITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVD--------HSLTLDERE-- 510
D +++T Q R+L ++ + + V L+ T +G+D LT R+
Sbjct: 488 YDTNEVTVTQERFLRNPGKLMQKRQQCWWVPLTFAT-AGIDSFVSTLPSEWLTCQGRQTA 546
Query: 511 ----LTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSK-----QSDLLTVEDRTGLVAD 561
L + ++ N A +Y + W + + + R L++D
Sbjct: 547 SPLILNEVAQPDKWVVFNLRLATPCRITYDERNWQLIGNALSGTNASSIDRFTRAQLISD 606
Query: 562 CKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEALDEFT 621
L+ +G + L + +NED F+VW+ L L + F
Sbjct: 607 VLNLAGAGVVTYDLALNFLGHLRNEDEFIVWQAADTYLEWLHR--TLRQTTIISTFKGFM 664
Query: 622 RQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTSG---D 678
R L+ K L F + S A E+ K +G +
Sbjct: 665 RDLLQTKFDEL---FKRDGSAAENANITELMVIVLQLSCRTDLESCADFALKEFAGLTLE 721
Query: 679 SNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDPALMKRT 738
+N IP + +++ T + G ++ L +Y + S+E+ L + + + +
Sbjct: 722 TNRIPVDLSETIYCTAIQFGTEADWTLLRRLYTRSNVSEERRILLSAMACSRENWALDKL 781
Query: 739 LGYLFDGTVL-NQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTMLGSILTV 797
L F G + D+ + + + G + +N A+ K + + L ++TV
Sbjct: 782 LNLAFAGRYMPKDDVLLIFSAVAQNPLGYNIAKKYLVDNIKAIIKLYGSNTDELAQLVTV 841
Query: 798 ATSGFTSRQAIDEIEDFFKD--KSTKGFDQSLAQTLDTITSKANWVDR 843
T+ + ++ + F + ++ GF+ + + L+ +W +R
Sbjct: 842 LMKEVTTEEELNALRMFMRTDLQNLPGFEIAFRRILELGEDNISWHNR 889
>7298258 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 578
Score = 166 bits (420), Expect = 1e-40
Identities = 134/504 (26%), Positives = 225/504 (44%), Gaps = 43/504 (8%)
Query: 108 DTMAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTH 167
D G++ YI+ T E + + + R P FDEP+LKA+F +T+ +
Sbjct: 18 DQRDGYFIRHYINWKTSEKIWYSVSHFNRNWIRNTMPSFDEPSLKATFNVTMGHHKRFQS 77
Query: 168 LSNMDVK----KEEIFDGKKFTYFNPTPKMSTYLVAFIVAELE--YVECKDFR-IPVRVY 220
NM V+ EI D ++ TP + T+L+AF V Y + + R
Sbjct: 78 YGNMKVQAVLPNREIQD-YVWSVHEVTPTIPTHLLAFSVNNFNCRYSQAASLSPVRFRTC 136
Query: 221 ATPGSEHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVV 280
A +AA + + L F ++ + PL K+D + V +F AMEN+GLV YR
Sbjct: 137 AQSADVRATSFAAQMAPQILEFLDRVLQVALPLEKIDQLVVDDFPTEAMENFGLVVYRSK 196
Query: 281 DLLLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQF 340
LLL E + + E++ HE+AH WF NL+ MD + LWL EG A + A +
Sbjct: 197 HLLLREDGPMSKEKLQTLELIAHEMAHMWFDNLLGMDSYSDLWLTEGLAGYFKSLAVDHL 256
Query: 341 QPEWKVWEQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMIS 400
Q K+ + + +S++ +S + VP+ +N + Y K +SL M+
Sbjct: 257 QS--KMGRRILLRYRESSMMYESQVGGISL-VPLSSNASLNA--ETQLYQKATSLTSMLI 311
Query: 401 QWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGK--------DVRNVMDIWTKKV 452
+LG + F G+ +++ + FG++ + W +L AS + DV+++MD WT +
Sbjct: 312 GFLGNETFYDGLQRHMWQNSFGSSTPDLFWRSLQLASEREATFDKTWDVKSIMDTWTMQS 371
Query: 453 GFPIVSVTEDGHKITFKQNRYLNTADVKPEEDKTLYPVFLSLKTNSG-----VDHSLTLD 507
G+P+V+V +G ++ KQ LN L+ + L+ G + L
Sbjct: 372 GYPLVTVIRNGSEVFLKQGHALN------RSSSHLWWIPLTYLIEGGSLSKNLKPKAWLS 425
Query: 508 ERELTVTVEDV----DFIKTNANQAGIYVTSYSDDRW----TTLSKQSDLLTVEDRTGLV 559
+ + D+ +I N G Y +Y + W TTL + V +R +V
Sbjct: 426 PNSHGIKLNDIVPRNQWILLNLQAVGYYRVNYDELTWQLLATTLFNDFRSINVLNRAQIV 485
Query: 560 ADCKTL---SLSGYTSTKNFLQLI 580
+D L L +++ N L+ I
Sbjct: 486 SDVLFLWNQDLLAWSTALNVLKYI 509
>7300975 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1114
Score = 160 bits (405), Expect = 8e-39
Identities = 147/663 (22%), Positives = 277/663 (41%), Gaps = 63/663 (9%)
Query: 240 LSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAE 299
L + + I YPL K+D VA+ + + GLVT + L D + + E+ + A
Sbjct: 459 LEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKT-SFLTDPSSITSEQYQFSAL 517
Query: 300 VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVADDLQSAL 359
+ + Q+FG + + + +WL EG ++ +A Q W + E Y+ +AL
Sbjct: 518 RIAEAMVRQFFGGITSRKVLKDVWLWEGLIQYLGIHALAPLQETWPLREMYLLKMATAAL 577
Query: 360 GLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKF 419
+D+++ I + F K +++ M+ +GED F + +L
Sbjct: 578 DIDAIQGWDSIMNGTSHDGNNEEFF----VQKTAAIFSMLHTAIGEDRFRGCLGSFLKVN 633
Query: 420 KFGNAKTEDLWDALSEAS--GKDVRNVMDIWTKKVGFPIVSVTEDGHKITFKQ------- 470
+F A+ DLW ++ + K+++++M +WT + GFP+++VT+ G+ I+ Q
Sbjct: 634 RFRTAEPTDLWTICTKKANGSKNIKDMMTLWTHQPGFPLLTVTKMGNSISISQRPFRPAE 693
Query: 471 -----------NRY----LNTADVK--------------PEEDKTLYPVFLSLKTNSGVD 501
N Y LN D+ K ++PV N+ V
Sbjct: 694 FLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKWIFPVTYVTDINN-VS 752
Query: 502 HSLTLDERELTVTV-EDVDFIKTNANQAGIYVTSYSDDRWTTLSKQ----SDLLTVEDRT 556
+L + ++T V E+V +IK NA Q G Y Y+DD W +L ++ + T EDR
Sbjct: 753 ETLWMQNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNWASLIEELAANPNRFTSEDRL 812
Query: 557 GLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEPKETLEA 616
G+++D TL + + + +I +E + + L + + E
Sbjct: 813 GMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLEKWRRILKY--SECFLM 870
Query: 617 LDEFTRQLVSEKTHSLGWEFSENESYASQRLKVEMFXXXXXXXXXXXXXXXXXMFEKYTS 676
L EF + +S +GW S++ A++ L+ E+ M +Y
Sbjct: 871 LSEFIKMKISTVMEKVGW--SDDGDVATRLLRPEVLLASVLWEDIDSITKAKNMLNQYLY 928
Query: 677 GDSNAIPPLIKSSVFGTVARDGN----AKNYEKLFAIYKNPSSSDEKLSALRCLGRFEDP 732
+ AIPP ++ V+ G +E+ + + + E++ LR LGR +D
Sbjct: 929 YNGTAIPPNLREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFVERMQLLRALGRTKDA 988
Query: 733 ALMKRTLGYLFDGTVL-NQDIYIPMGGMRGHKEGIKTLWAWTKENWDALHKKFPPSLTML 791
L R L ++ T+L +++ + + G G + + W L K+ P
Sbjct: 989 WLQNRLLSHV---TMLPTEEVVQVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISF 1045
Query: 792 GSILTVATSGFTSRQAIDEIEDFFKDKSTKGFDQS-LAQTLDTITSKANWVDRDREVVVK 850
+++ T ++ DE++ + +G S L TL ++ S WV R + + K
Sbjct: 1046 AKVISAITQYGATKFDYDELKSLV-HRFGRGHGMSVLNMTLSSVASNVEWVARSQTSLYK 1104
Query: 851 FLK 853
+++
Sbjct: 1105 WVE 1107
Score = 89.0 bits (219), Expect = 3e-17
Identities = 74/244 (30%), Positives = 117/244 (47%), Gaps = 16/244 (6%)
Query: 9 ILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKI---- 64
+LP +V PL Y + + P T G V+IDL V +KE++F+ L+ +L++ E I
Sbjct: 126 MLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHV-EKETNFIVLHIQDLNVTEKAIVTPG 184
Query: 65 --NDVKSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNA 122
+ V + + + LK N T+++++ LN GFY +Y +++
Sbjct: 185 PKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQY-ESS 243
Query: 123 TGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEE----- 177
G + +A T P ARRAFPCFDEP+++A F I++ D LSN V E
Sbjct: 244 NGVERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFY 303
Query: 178 IFDGKKFTYFNPTPKMSTYLVAFIVAEL--EYVECKDFRIPVRVYATPGSEHLGQYAANL 235
+ G F TP + VA++V++ E ++ IP A PGS G+ +A L
Sbjct: 304 MGTGLLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPT-TPAPPGSGVGGKKSAQL 362
Query: 236 TAKT 239
T
Sbjct: 363 NNYT 366
>CE05135 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 1071
Score = 152 bits (384), Expect = 2e-36
Identities = 173/784 (22%), Positives = 312/784 (39%), Gaps = 66/784 (8%)
Query: 90 LKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGETKYMATTQMEPTDARRAFPCFDEP 149
LK V + I FT +++ G KY N+ G+ + M TTQ + R FP FD+
Sbjct: 289 LKKGSTVVLKIPFTSKVSNNN-GLKEYKY-KNSEGKEQSMFTTQPSYSYLRHVFPSFDQE 346
Query: 150 NLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVE 209
KA ITL+ ++N VK ++ D + T F++ +L E
Sbjct: 347 AFKAPAAITLMHSKGSIVVANTGVKTKDDGDAQTSTLNKVLDP------DFVIGDLVASE 400
Query: 210 CKDFR-IPVRVYATPGSEHLGQYAANLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGA 268
I +R++ P +H + + + + + E +D VAV F G
Sbjct: 401 VNTTSGITIRIWTRPEVKHSTEQSLDYANQAIDAMEHILQSRLESKSLDIVAVPGFQTGN 460
Query: 269 MENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGF 328
+ + D+L +E++ + + R+A ++ + +A QWFG + + + WLNE
Sbjct: 461 RVSPSFIVLPEEDILYNEQSNDINQKTRIARMISNRIAAQWFGGITNPEEFGTFWLNEAL 520
Query: 329 ATWMSWYACNQFQP--EWKVWEQYVADDLQSALGLDSLRSSHPIEVP-VKRADEINQIFD 385
++ A + +W +++ L D+ +S P+ V V + +I +I
Sbjct: 521 PRFLEVEALEKILDINSDDLWTY----EMEKILERDATATSQPLRVKNVFSSADIAEIDH 576
Query: 386 HISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASG------- 438
KG+++LRMI + +G +VF K + +++ ++ + LW + +A G
Sbjct: 577 EFIGKKGAAVLRMIQKSVGVNVFNKAIRSFVSSYRSAYPYDDGLWKSFEKALGGKLKGWN 636
Query: 439 ---KDVRNVMDIWTKKVGFPIVSVTE-DGHKITFKQNRYLNTADVKPEEDKTLYPVFLSL 494
DV ++ W ++GFP+VSV + D + Q R+ N K E+ K F +
Sbjct: 637 NEPLDVAKFVNTWVDQIGFPLVSVEKLDDETVELSQERFKNDHKTK-EQFK-----FRNA 690
Query: 495 KTNSGVDHSLTLDERELTVTVEDVDFIKTNANQAGIYVTSYSDDRWTTLSKQSD----LL 550
K + + L + D ++ T++N G+Y +Y + RW ++KQ + L
Sbjct: 691 K------YWFNWEVPLLPLNTSDSIYLNTDSN--GVYRVNYEEKRWNDIAKQLEKSHGKL 742
Query: 551 TVEDRTGLVADCKTLSLSGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKAAWAFEP 610
+ R L++D L+ SG + L + S E + V W +I + K E
Sbjct: 743 SERTRARLISDVFALANSGALPFETALNVTSYLPMETATVPW--LIATRIFKKLTERLEG 800
Query: 611 KETLEALDEFTRQLVSEKTHSLGWEFSE-NESYASQRLKVEMFXXXXXXXXXXXXXXXXX 669
+ L+ F Q + +K + E + +Y RL +
Sbjct: 801 APIQDKLNSFIYQKIHKKFEEISSSPGEASSNYLKNRLYANLLDLMAIVKPEKSNEKLNE 860
Query: 670 MFEK----------YTSGDSNAIPPLIKSSVFGTVARDGNAKNYEKLFAIYKNPSSSDEK 719
+F + S D + +P ++ V+ GN +E + + + EK
Sbjct: 861 LFVEGFLAPCQFSGNFSSDCSEVPGDLREKVYCNGVEFGNDTVFETVRELAEKEVDGAEK 920
Query: 720 LSALRCLGRFEDPALMKRTLGYLFDGTVLNQDIYIPMGGMRGHKEGIKTLWAWTKENWD- 778
L F DP ++R + D + + + M G + W +NW
Sbjct: 921 DLLQNSLACFRDPRALRR---LILDNLNSTSTVTLLLRKMNSRPVGKEIATNWIIDNWST 977
Query: 779 ALHKKFPPSLTMLGSILTVATSGFTSRQAIDEIEDFFK--DKSTKGFDQSLAQTLDTITS 836
L KKF L +I R+ IE F + KST G +SL + ++ T+
Sbjct: 978 VLKKKFKNDPETLNAIADAGIILDNEREK-SMIETFMEHHHKSTHGI-ESLDKKIEEATT 1035
Query: 837 KANW 840
W
Sbjct: 1036 DIYW 1039
>7294697 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 887
Score = 126 bits (317), Expect = 1e-28
Identities = 153/637 (24%), Positives = 273/637 (42%), Gaps = 66/637 (10%)
Query: 14 VSPLHYKL----QLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKI----- 64
V PL Y L +L + +F+G VSID++ + + + LN+ + I +
Sbjct: 22 VKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEAT-QPTRVIYLNSLNITISRQRTWIYRW 80
Query: 65 ---NDVKSLETVTDEENQTSRFKFPAGT-LKDSDNVTIDIKFTGILNDTMAGFYRAKYID 120
+ +L+ + +TS K L+ + T+++ F+G L+ + Y A Y D
Sbjct: 81 ASGRKIGALQ-IKRIIKKTSLIKIVIELPLRSGEIYTLNMLFSGNLDRSQQYGYFAGYYD 139
Query: 121 NATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF- 179
+ + T++EP A FPCFD+P + + ITLV D K LSNM +E+ +
Sbjct: 140 KTP--RVFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYK 197
Query: 180 --DGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRI--PVRVYATPGSEHLGQYAANL 235
+ T F +P ++T V + + +LE V + V++ P HL + A +
Sbjct: 198 EIENYVSTTFMGSPPLATQQVMWTLHQLEKVYSGPAAAGENITVWSRP---HLAEKLAKV 254
Query: 236 TAKTLSFFEKAFGI-EYPLP-------KMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEK 287
T + F K + YPLP K+D V + ++ G++ Y + ++D
Sbjct: 255 PEMTPNLFSKYETLFAYPLPKGADWGGKVDHVVLPRYTE-MYSGQGIMVYG--EDIVDSG 311
Query: 288 NASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVW 347
LE ++ E + +A QW G LV ++ + ++ G ++S + +
Sbjct: 312 QNGLESLQ---ETLAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNT- 367
Query: 348 EQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDV 407
+++ L DSL I VK + + K L+ M+ LG+ +
Sbjct: 368 -THLSKTRLDVLYHDSLAKVKSIATDVKESGH-----QKLRKKKMCLLIHMLKVALGDKL 421
Query: 408 FVKGVSQYLNKFKFGNAKTEDLWDALSEA--------SGKDVRNVMDIWTKKVGFPIVSV 459
F+KG+ ++ ++ +A +++LW+ +G + VM+ W K+ GFP+++V
Sbjct: 422 FLKGLQEFFKRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTV 481
Query: 460 TEDGHK--ITFKQNRYLNTADVKPEEDKTLYPVFLSLK--TNSGVD----HSLTLDEREL 511
D K +T Q+RY D PV ++ T V+ + D EL
Sbjct: 482 QRDDAKQIVTITQSRYYQKYLDNSSNDCWWVPVAYIVRNLTLPQVEWLGCQKNSRDILEL 541
Query: 512 TVTVEDVDFIKTNANQA---GIYVTSYSDDRWTTLSKQSDLLTVE-DRTGLVADCKTLSL 567
+ D++ N + A ++ SY+ + +Q E R LV D +LS
Sbjct: 542 SHIANPEDWLLINVDAAVPLRVFYDSYNLQLISEALRQDFTQIPELSRIQLVDDALSLSW 601
Query: 568 SGYTSTKNFLQLISQWKNEDSFVVWEQMINSLGSLKA 604
SG L +IS NE S +VWE + +L L++
Sbjct: 602 SGRLPYNVTLNVISYLSNETSVLVWETALLNLEKLQS 638
>CE13593 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 556
Score = 116 bits (290), Expect = 2e-25
Identities = 120/448 (26%), Positives = 180/448 (39%), Gaps = 54/448 (12%)
Query: 131 TTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSN---MDVKKEEIFDGKKF--T 185
TT ++P ARR FPC D P +KA F +++V SN MDV E +K+ T
Sbjct: 50 TTHLQPNHARRLFPCIDHPAVKALFRLSIVHPTDTVAQSNTIAMDVHVEN----RKWQRT 105
Query: 186 YFNPTPKMSTYLVAFIV---AELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSF 242
F TP + YLVAF V + L+ F + VRV E G L SF
Sbjct: 106 IFQATPLLPAYLVAFSVMPDSNLQLSRQTSFGVTVRV----NGESRGLVLRVLDCALASF 161
Query: 243 FEKAFGIEYPLP--KMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEV 300
A I+ PLP K+D + V E+ G MENWG +T + E A+ + +
Sbjct: 162 EILAGLIDVPLPLNKIDFILVPEYDGG-MENWGHIT-------VSETLATSGDDAHLIYL 213
Query: 301 VQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQ-FQPEWKVWEQYVADDLQSAL 359
+ HE+AH W GN T+D W + L E WM+ A E ++ +A ++ L
Sbjct: 214 IAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAVKALLTDEIRLQRFQLAQYVEIQL 273
Query: 360 GLDSLRSSHPIEVPVKRADEINQ-IFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNK 418
D L H + +P K INQ + + Y KG LL + +GE + +
Sbjct: 274 VEDFLSPGHSLYMPSK----INQELINRHCYLKGVVLLDTLESVVGEQFMYSVIKSLVGS 329
Query: 419 FKFGNAKT-EDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTEDGHKITFKQNRYLNTA 477
N T +D + V + + W G+P + V +G +Q
Sbjct: 330 HSTYNLTTFTSYFDQIRVDRNATVGQIYEYWYTTGGYPSILVENNGPSSRLQQ------- 382
Query: 478 DVKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTVTVEDVDFIKTNANQAGIYVTSYSD 537
+ L+P LK S + + + E+ + N N +Y
Sbjct: 383 -----LSRPLWP----LKMTSTLAIPQFVFSESIVFASENAPLL-VNLNFTSFMRVNYDS 432
Query: 538 DRWTTLSK----QSDLLTVEDRTGLVAD 561
WT + K + +L + R LV+D
Sbjct: 433 LTWTAIFKYMFEEPELFSAVGRAQLVSD 460
>CE24840 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 609
Score = 115 bits (288), Expect = 3e-25
Identities = 121/465 (26%), Positives = 197/465 (42%), Gaps = 43/465 (9%)
Query: 12 QNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN----DV 67
+ V+ HY L+ + F+ G VSI L V ++++ + L+T +L + +N
Sbjct: 16 EQVTVSHYALKWKVDFEKKHIAGDVSITLDVK-QDTERIVLDTRDLSVQSVALNLNGEPK 74
Query: 68 KSLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGETK 127
K+ T+ D + + +LK D ++IK+ N F A + T
Sbjct: 75 KAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTA---EQTTDRVA 131
Query: 128 YMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTYF 187
+Q + +AR PC D P++K+++E + LT L + + + K T F
Sbjct: 132 PYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIF 191
Query: 188 NPTPKMS--TYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSFFEK 245
+ +S +YL+A +V LE E + V+A P Y T K L E
Sbjct: 192 SFKQPVSIPSYLLAIVVGHLERKEISE---RCAVWAEPSQAEASFYEFAETEKILKVAED 248
Query: 246 AFGIEYPLPKMDSVAVHE-FSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHE 304
G Y + D V + F G MEN +T+ LL +++ + V+ HE
Sbjct: 249 VAG-PYVWGRYDLVVLPATFPFGGMEN-PCLTFITPTLLAGDRS--------LVNVIAHE 298
Query: 305 LAHQWFGNLVTMDWWEGLWLNEGFATW--------MSWYACNQFQPEWKVWEQYVADDLQ 356
++H W GNLVT WE WLNEGF + M QF+ E +E+ + +
Sbjct: 299 ISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMYGELERQFESE-SGYEEALVRTVN 357
Query: 357 SALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDV-FVKGVSQY 415
G D + + AD + F + Y KGS+LL I Q LG++ F + + Y
Sbjct: 358 DVFGPD--HEYTKLVQNLGNADP-DDAFSSVPYEKGSALLFTIEQALGDNSRFEQFLRDY 414
Query: 416 LNKFKFGNAKTEDLWDALSEASGKDVRNVMD-----IWTKKVGFP 455
+ K+ + TE+ W S D + ++D +W K G P
Sbjct: 415 IQKYAYKTVSTEE-WKEYLYDSFTDKKVILDNIDWNLWLHKAGLP 458
>7298498 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 613
Score = 104 bits (260), Expect = 5e-22
Identities = 123/475 (25%), Positives = 206/475 (42%), Gaps = 50/475 (10%)
Query: 3 SQPDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEA 62
SQPD I S L++K+ F K G+V KV D + L+ ++++ A
Sbjct: 13 SQPDLITTEH--SALNWKID----FAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNA 66
Query: 63 KINDVKS-------LETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYR 115
+ S + D+ Q + P+GT K S NV ID + + + +G
Sbjct: 67 TLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYE----TSSSASGLQW 122
Query: 116 AKYIDNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKK 175
E YM + Q + AR PC D P +K +++ T+ +LT L + + K
Sbjct: 123 LNPTQTLGKEHPYMFS-QCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALIDK 181
Query: 176 EEIFDGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANL 235
+E GK T F + YLVA + +L + V+A E + A
Sbjct: 182 KE--PGK--TLFKQEVPIPAYLVAIAIGKLV---SRPLGENSSVWA---EEAIVDACAEE 231
Query: 236 TAKTLSFFEKAFGI--EYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLE 292
++T + + A + Y + D + + F G MEN +T+ LL +K+
Sbjct: 232 FSETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMEN-PCLTFVTPTLLAGDKS---- 286
Query: 293 RIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVA 352
+A+VV HE+AH W GNLVT +E WLNEGF ++ + Q ++ + ++
Sbjct: 287 ----LADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLS 342
Query: 353 D--DLQSALGLDSLRSSHPIEVPVKRAD-EINQIFDHISYAKGSSLLRMISQWL-GEDVF 408
+ DLQ + ++ ++ V ++ + F + Y KGS+ LR + G VF
Sbjct: 343 NLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVF 402
Query: 409 VKGVSQYLNKFKFGNAKTED----LWDALSEASGKDVRNVM--DIWTKKVGFPIV 457
+ YL K+ + + +T+D L+D + KD + + D+W K G P V
Sbjct: 403 EPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDKKDKLSAVDWDLWLKSEGMPPV 457
>At1g63770 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 964
Score = 100 bits (249), Expect = 1e-20
Identities = 116/526 (22%), Positives = 207/526 (39%), Gaps = 30/526 (5%)
Query: 5 PDRIILPQNVSPLHYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKI 64
P I L P +Y ++ F + VS +KV+ + LD H+ K+
Sbjct: 81 PKEIFLKNYTKPDYYFETVDLSFSLGEEKTIVSSKIKVSPRVKG--SSAALVLDGHDLKL 138
Query: 65 NDVK---SLETVTDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDN 121
VK L D + + P+ ++S + ID + N ++ G Y++
Sbjct: 139 LSVKVEGKLLKEGDYQLDSRHLTLPSLPAEESFVLEIDTEIYPHKNTSLEGLYKS----- 193
Query: 122 ATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKL--THLSNMD-VKKEEI 178
+G TQ E R+ D P++ A + + D L LSN + + + +I
Sbjct: 194 -SGNF----CTQCEAEGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNGNLISQGDI 248
Query: 179 FDGKKFTYFNPTPKMSTYLVAFIVAEL-----EYVECKDFRIPVRVYATPGSEHLGQYAA 233
G+ + + K YL A + +L + ++ ++++ +A
Sbjct: 249 EGGRHYALWEDPFKKPCYLFALVAGQLVSRDDTFTTRSGRQVSLKIWTPAEDLPKTAHAM 308
Query: 234 NLTAKTLSFFEKAFGIEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLER 293
+ + E FG+EY L + VAV +F+ GAMEN L + +L + A+
Sbjct: 309 YSLKAAMKWDEDVFGLEYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASPETATDAD 368
Query: 294 IKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVAD 353
+ V+ HE H W GN VT W L L EG + + V+
Sbjct: 369 YAAILGVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDMGSRTVKRIADVSK 428
Query: 354 DLQSALGLDSLRSSHPIEVP--VKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKG 411
D+ +HP+ +K +++ + + G+ ++RM LG F KG
Sbjct: 429 LRIYQFPQDAGPMAHPVRPHSYIKVYEKVWLFTNSVLLYAGAEVVRMYKTLLGTQGFRKG 488
Query: 412 VSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIVSVTE----DGHKIT 467
+ Y + ED + A+ +A+ D N + W + G P+V V D +
Sbjct: 489 IDLYFERHDEQAVTCEDFFAAMRDANNADFANFLQ-WYSQAGTPVVKVVSSYNADARTFS 547
Query: 468 FKQNRYLNTADVKPEEDKTLYPVFLSLKTNSGVDHSLTLDERELTV 513
K ++ + +P ++ T PV + L +SG D +L+ + TV
Sbjct: 548 LKFSQEIPPTPGQPTKEPTFIPVVVGLLDSSGKDITLSSVHHDGTV 593
>YNL045w [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 671
Score = 88.6 bits (218), Expect = 4e-17
Identities = 110/454 (24%), Positives = 182/454 (39%), Gaps = 38/454 (8%)
Query: 17 LHYKLQLEPYFDTFKFDGTVSIDLKV---NDKESDFVELNTFELDIHEAKINDVKSLETV 73
LH L L F+ G+V+ LK +SD + L+T LD+ E I+ K+ +
Sbjct: 70 LHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKA-DFQ 128
Query: 74 TDEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGETKYMATTQ 133
++ + + +DN T++I+F T + +K T K +Q
Sbjct: 129 IEQRKEPLGSRLVINNASCNDNFTLNIQFRTTDKCTALQWLNSKQ----TKGGKPYVFSQ 184
Query: 134 MEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTYFNPTPKM 193
+E AR FPCFD P++K++F ++ S + ++ E+ F +
Sbjct: 185 LEAIHARSLFPCFDTPSVKSTFTASIESPLPVVF---SGIRIEDTSKDTNIYRFEQKVPI 241
Query: 194 STYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYA-ANLTAKTLSFFEKAFGIEYP 252
YL+ +L VY P Q+ N K + EK EY
Sbjct: 242 PAYLIGIASGDLSSAPIGP---RSTVYTEPFRLKDCQWEFENDVEKFIQTAEKII-FEYE 297
Query: 253 LPKMD-SVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQWFG 311
D V V + G ME+ + T+ L+ +++ +V+ HELAH W G
Sbjct: 298 WGTYDILVNVDSYPYGGMESPNM-TFATPTLIAHDRSN--------IDVIAHELAHSWSG 348
Query: 312 NLVTMDWWEGLWLNEGFATWMSWYACNQFQPE-WKVWEQYVA-DDLQSALGLDSLRSSHP 369
NLVT W WLNEG+ ++ E + + + DLQ++ +DS++
Sbjct: 349 NLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNS--IDSMKDPER 406
Query: 370 IEVPVKRAD---EINQIFDHISYAKGSSLLRMISQWL-GEDVFVKGVSQYLNKFKFGNAK 425
V+ + + + F + Y KG +LL + L G+ F + Y KF +
Sbjct: 407 FSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLD 466
Query: 426 TEDLWDALSE--ASGKDVRNVMD--IWTKKVGFP 455
T D L E K++ + +D W K G P
Sbjct: 467 TFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMP 500
>CE28160 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 625
Score = 87.8 bits (216), Expect = 6e-17
Identities = 86/337 (25%), Positives = 147/337 (43%), Gaps = 29/337 (8%)
Query: 132 TQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTYFNPTP 191
+Q + AR PC D P++K+++E + +T L + + + D ++
Sbjct: 140 SQCQAIHARSIVPCMDTPSVKSTYEAEVTVPTGMTCLMSAIGQGSKGDDDTTTFFYKQPV 199
Query: 192 KMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSFFEKAFGIEY 251
+ +YL+A +V LE + D V+A P + T L+ E+ G +Y
Sbjct: 200 AIPSYLIAIVVGCLEKRDISD---RCAVWAEPSVVDKAHWEFAETEDILASAEEIAG-KY 255
Query: 252 PLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQWF 310
+ D V + F G MEN +T+ L+ +++ + V+ HE+AH W
Sbjct: 256 IWGRYDMVCLPPSFPFGGMEN-PCLTFLTPTLIAGDRS--------LVSVIAHEIAHSWS 306
Query: 311 GNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVA-----DDLQSALGLDSLR 365
GNLVT WE WLNEGF ++ C + E + Q++A + L A+ +
Sbjct: 307 GNLVTNSSWEHFWLNEGFTMFIERKICGRLVSE--DYRQFMAFNGWTNSLIPAV-YEQFT 363
Query: 366 SSHPIEVPVKRADEINQ--IFDHISYAKGSSLLRMISQWL-GEDVFVKGVSQYLNKFKFG 422
+H ++ ++ F + Y KGS+LL + Q L G ++F + YL F
Sbjct: 364 PTHQFTKLIQDHTNVDPDVAFSCVPYEKGSALLFYLEQKLGGSEIFEAYLKDYLKTFAHQ 423
Query: 423 NAKTEDLWDALSE--ASGKDVRNVM--DIWTKKVGFP 455
+ D L + A K+V + + D+W VG P
Sbjct: 424 AIDSWQWKDHLYKYFADQKEVLDTVNFDLWFNGVGMP 460
>Hs4505029 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 611
Score = 84.0 bits (206), Expect = 9e-16
Identities = 106/463 (22%), Positives = 189/463 (39%), Gaps = 39/463 (8%)
Query: 18 HYKLQLEPYFDTFKFDGTVSIDLKVNDKESDFVELNTFELDIHEAKIN--DVK-SLETVT 74
H L+ F GT ++ ++ + + L+T +L I + IN +VK +L
Sbjct: 21 HLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQ 80
Query: 75 DEENQTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGETKYMATTQM 134
+ P K+ + + I+I F + + + +G+ +Q
Sbjct: 81 SYKGSPMEISLPIALSKNQE-IVIEISFETSPKSSALQWLTP---EQTSGKEHPYLFSQC 136
Query: 135 EPTDARRAFPCFDEPNLKASFEITLVSDPK-----LTHLSNMDVKKEEIFDGKKFTYFNP 189
+ R PC D P++K ++ VS PK ++ + + + E K + +
Sbjct: 137 QAIHCRAILPCQDTPSVKLTYTAE-VSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQK 195
Query: 190 TPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSFFEKAFGI 249
P + YL+A +V LE + V++ Y + T L E G
Sbjct: 196 VP-IPCYLIALVVGALE---SRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGG- 250
Query: 250 EYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQ 308
Y + D + + F G MEN +T+ LL +K+ S V+ HE++H
Sbjct: 251 PYVWGQYDLLVLPPSFPYGGMEN-PCLTFVTPTLLAGDKSLS--------NVIAHEISHS 301
Query: 309 WFGNLVTMDWWEGLWLNEGFATWMSWYACNQ-FQPEWKVWEQYVA-DDLQSALGLDSLRS 366
W GNLVT W+ WLNEG ++ + C + F +++ + +LQ++ + +
Sbjct: 302 WTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNS--VKTFGE 359
Query: 367 SHPIEVPVKRADEINQ--IFDHISYAKGSSLLRMISQWL-GEDVFVKGVSQYLNKFKFGN 423
+HP V +I+ + + Y KG +LL + Q L G ++F+ + Y+ KF + +
Sbjct: 360 THPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKS 419
Query: 424 AKTEDLWDALSE--ASGKDVRNVMD--IWTKKVGFPIVSVTED 462
T+D D L DV N +D W G P + D
Sbjct: 420 ITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYD 462
>Hs13443031 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 657
Score = 78.6 bits (192), Expect = 4e-14
Identities = 87/356 (24%), Positives = 147/356 (40%), Gaps = 43/356 (12%)
Query: 120 DNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF 179
+ G+ K TQ + R FPCFD P +K + + T + M + E
Sbjct: 164 EQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAV--MSARPGEKR 221
Query: 180 DGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKT 239
KF +F + +YL+A + +L E RV+A P + + +
Sbjct: 222 GPNKF-FFQMCQPIPSYLIALAIGDLVSAEVGPRS---RVWAEPCLIDAAKEYNGVIEEF 277
Query: 240 LSFFEKAFGIEYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVA 298
L+ EK FG Y + D + + F G MEN +T+ LL +++ +A
Sbjct: 278 LATGEKLFG-PYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGDRS--------LA 327
Query: 299 EVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWM----------SWYACNQFQPEWKVWE 348
+V+ HE++H WFGNLVT W WLNEGF + + Y C + +
Sbjct: 328 DVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLR 387
Query: 349 QYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLG-EDV 407
Q++ D L+ LR V ++ + + ++ Y KG + ++ +G +D
Sbjct: 388 QHM-DITGEENPLNKLR------VKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQ 440
Query: 408 FVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDI--------WTKKVGFP 455
F + Y+++FKF + +D D E + + +DI W G+P
Sbjct: 441 FDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWP 496
>Hs20537652 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 650
Score = 75.9 bits (185), Expect = 3e-13
Identities = 85/357 (23%), Positives = 147/357 (40%), Gaps = 44/357 (12%)
Query: 120 DNATGETKYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIF 179
+ G+ K TQ + R FPCFD P +K + + T + + ++
Sbjct: 156 EQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKR-- 213
Query: 180 DGKKFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAAN-LTAK 238
G +F + +YL+A + +L E RV+A P + N + +
Sbjct: 214 -GPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRS---RVWAEPCLIDAAKEEYNGVIEE 269
Query: 239 TLSFFEKAFGIEYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRV 297
L+ EK FG Y + D + + F G MEN +T+ LL +++ +
Sbjct: 270 FLATGEKLFG-PYVWGRYDLLFMPPSFPFGGMEN-PCLTFVTPCLLAGDRS--------L 319
Query: 298 AEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWM----------SWYACNQFQPEWKVW 347
A+V+ HE++H WFGNLVT W WLNEGF + + Y C + +
Sbjct: 320 ADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALL 379
Query: 348 EQYVADDLQSALGLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLG-ED 406
Q++ D L+ LR V ++ + + ++ Y KG + ++ +G +D
Sbjct: 380 RQHM-DITGEENPLNKLR------VKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQD 432
Query: 407 VFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKDVRNVMDI--------WTKKVGFP 455
F + Y+++FKF + +D D E + + +DI W G+P
Sbjct: 433 QFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWP 489
>At5g13520 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 616
Score = 70.1 bits (170), Expect = 1e-11
Identities = 92/364 (25%), Positives = 140/364 (38%), Gaps = 66/364 (18%)
Query: 132 TQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLT------HLSNMDVKKEE-------- 177
TQ + AR FPC D P + +++ + L+ H+ EE
Sbjct: 127 TQCQAIHARSIFPCQDTPAARIRYDVVMNIPNSLSAVMSARHVRRRLAVPEEAKHLEAGS 186
Query: 178 ----IFDGK-----KFTYFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHL 228
++ G+ +F P P YL AF V EL + E RVY + +
Sbjct: 187 LGSSLWCGEDRVVEEFAMEQPIPP---YLFAFAVGELGFREVGP---RTRVYTESAAIEV 240
Query: 229 GQYAANLTAKTLSFF---EKAFGIEYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLL 284
AA A T EK FG +Y + D + + F G MEN +V +
Sbjct: 241 LDAAALEFAGTEDMIKQGEKLFG-DYEWERFDLLVLPPSFPYGGMENPRMVFLTPTVIKG 299
Query: 285 DEKNASLERIKRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEW 344
D A +VV HELAH W GNL+T E WLNEGF T+ E
Sbjct: 300 DATGA---------QVVAHELAHSWTGNLITNINNEHFWLNEGFTTY----------AER 340
Query: 345 KVWEQYVADD---LQSALGLDSL-----RSSHPIEVP----VKRADEINQIFDHISYAKG 392
++ E D L +G L R +E + + + ++ + Y KG
Sbjct: 341 RIVEVVQGADIATLNIGIGWRGLTDEMERFKDNLECTKLWNKQEGVDPDDVYSQVPYEKG 400
Query: 393 SSLLRMISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDAL-SEASGKDVRNVMDIWTKK 451
+ I + +G F + + +Y+ FKF + T + L + G + + +WT+
Sbjct: 401 FQFVLRIERQIGRTAFDEFLKKYIATFKFKSIDTNTFLEFLKANIPGIEKEINLQLWTEG 460
Query: 452 VGFP 455
VG P
Sbjct: 461 VGIP 464
>Hs17472410 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 365
Score = 68.2 bits (165), Expect = 5e-11
Identities = 38/84 (45%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
Query: 127 KYMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGK-KFT 185
K +A T EPTDAR+ FPCFD+PN KA++ I++ + LS+M V KEE D K T
Sbjct: 240 KSIAATDHEPTDARKFFPCFDKPNKKATYTISVTHPKEYEALSHMPVAKEESVDDKWNQT 299
Query: 186 YFNPTPKMSTYLVAFIVAELEYVE 209
F + MS YLV F V + V+
Sbjct: 300 TFKKSVPMSMYLVCFAVHQFHTVK 323
>SPCC1322.05c [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 612
Score = 62.8 bits (151), Expect = 2e-09
Identities = 103/462 (22%), Positives = 179/462 (38%), Gaps = 38/462 (8%)
Query: 13 NVSPLHYKLQLEPYFDTFKFDGTVSIDL---KVNDKESDFVELNTFELDIHEAKINDVKS 69
++S L + +++ FD G VS + +V+ S + L+T L+I IND+ +
Sbjct: 17 SISKLDWHARID--FDQELLHGKVSFVIQSARVSQALSHII-LDTSYLEIKNVTINDIPT 73
Query: 70 LETVTDEEN--QTSRFKFPAGTLKDSDNVTIDIKFTGILNDTMAGFYRAKYIDNATGETK 127
V ++ PA + S + + I ++ + T F + + G+
Sbjct: 74 PFRVDKRRGFLGSALHIVPADEIPSSKSCILTILYSTTKDCTALQFLKPE--QTIGGKFP 131
Query: 128 YMATTQMEPTDARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDVKKEEIFDGKKFTYF 187
Y+ + + + AR PC D P++K + S + S + +G F
Sbjct: 132 YVFS-ECQAIHARSFIPCQDTPSVKVPCTFKIRSKLPVI-ASGIPCGTANFCNGSLEYLF 189
Query: 188 NPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSFFEKAF 247
+ +YL + +L VY PG+ +Y + +
Sbjct: 190 EQKNPIPSYLFCILSGDLASTNIGPRS---SVYTEPGNLLACKYEFEHDMENFMEAAEQL 246
Query: 248 GIEYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELA 306
+ Y + D V + F G MEN T+ L+ +++ V+ HELA
Sbjct: 247 TLPYCWTRYDFVILPPSFPYGGMENPN-ATFATPTLIAGDRSN--------VNVIAHELA 297
Query: 307 HQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPE-WKVWEQYVA-DDLQSALGLDSL 364
H W GNLVT + W+ WLNEG ++ + E + +E + +L+ ++ L
Sbjct: 298 HSWSGNLVTNESWQCFWLNEGMTVFLERKILGRLYGEPTRQFEAIIGWGELEESVKLLGE 357
Query: 365 RSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWL-GEDVFVKGVSQYLNKF---- 419
S + + + + F + Y KGS+ L I + + G VF + Y KF
Sbjct: 358 DSEYTKLIQNLEGRDPDDAFSTVPYEKGSNFLYEIERVIGGPSVFEPFLPFYFRKFAKST 417
Query: 420 ----KFGNAKTEDLWDALSEASGKDVRNVMDIWTKKVGFPIV 457
KF +A E + L AS D + D W G P V
Sbjct: 418 VNEVKFKHALYE-YFSPLGLASKLDSID-WDTWYHAPGMPPV 457
>CE25399 [EO] KOG1046 Puromycin-sensitive aminopeptidase and related
aminopeptidases
Length = 735
Score = 60.1 bits (144), Expect = 1e-08
Identities = 98/452 (21%), Positives = 178/452 (38%), Gaps = 55/452 (12%)
Query: 136 PTDARRAFPCFDEPNLKASFEITLVSDP---KLTHLSNMDVKKEEIFDGKKFTYFNPTPK 192
P A FP + K +F IT+V LT SN ++ I + + T F+ TP
Sbjct: 181 PNRAPAVFPSYLASTEKVTFSITMVHPVGTLALTSGSNEGAPRK-IDENWQMTTFSTTPS 239
Query: 193 MSTYLVAFIVAELEYVECKD----FRIPVRVYATPGSEHLGQYAANLTAKTLSFFEKAFG 248
++ ++ F++ EY + I V + ++ + + L+ + F
Sbjct: 240 ITPSMLCFLLLPHEYTHIESTYTGVNISVHYNRFRVQKEQTKHLLHTATQVLALLKDIFS 299
Query: 249 IEYPLPKMDSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQHELAHQ 308
P+PK+D + ++E S+ A +V V D N ++K +A LA Q
Sbjct: 300 SLIPVPKIDIITMNEVSSTACFG-SIVVSEVQFFSADYAN----QVKMLAT----WLAKQ 350
Query: 309 WFGNLVTMDWWEGLWLNEGFATWMS-----WYACNQFQPEWKVWEQYVADDLQSALGLDS 363
W G + L L E +++ ++F + + Y+++ + +A D+
Sbjct: 351 WIGGYAAISEGSELCLQEDLVAFIADKVIKRMTNDEFTRLGHLAKIYLSETIFTA--GDT 408
Query: 364 LR-SSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKFKFG 422
L+ HP E +IF+ KG ++L I +GE + +++ + K G
Sbjct: 409 LKLDEHPNEF---------EIFEKCG-LKGVAMLESIESLIGEKSMISKINEMIYNSKKG 458
Query: 423 NAKTEDLWDALSEASGKD--VRNVMDIWTKKVGFPIVSVTEDGHKITFKQNRYLNTA--D 478
+ + L+ L+ +D V ++ W + G P ++V + I QN T
Sbjct: 459 SYSSRTLYGLLNSTVDEDIYVSQLLHYWHEHGGLPYMNVDRLANSIKITQNGSNMTVKNG 518
Query: 479 VKPEEDKTLYPVFL-----SLKTNSGVDHSLTLDERELTVTVEDVDFIKTNANQAGIYVT 533
E L+P+ L L V H + L + D I +N Y
Sbjct: 519 AGTWERMPLWPLPLKFTEFKLPIQIMVSHGIHLS------PIRD-GLIFSNLGFTNYYRV 571
Query: 534 SYSDDRW----TTLSKQSDLLTVEDRTGLVAD 561
+Y D W T L++ + T+ +R LV+D
Sbjct: 572 NYDIDTWREIKTVLTENATSYTLRERFQLVSD 603
>Hs20070296 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 494
Score = 58.9 bits (141), Expect = 3e-08
Identities = 72/262 (27%), Positives = 115/262 (43%), Gaps = 37/262 (14%)
Query: 186 YFNPTPKMSTYLVAFIVAELEYVECKDFRIPVRVYATPGSEHLG-QYAANLTAKTLSFFE 244
+F+ + YLVA + +L+ D RV+A P + + LS E
Sbjct: 16 HFHMEHPVPAYLVALVAGDLKPA---DIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAE 72
Query: 245 KAFGIEYPLPKMDSVAVH-EFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQH 303
+ +G Y + D V + F AMEN +T+ + +L ++ ++ I H
Sbjct: 73 RLYG-PYMWGRYDIVFLPPSFPIVAMEN-PCLTFIISSILESDEFLVIDVI--------H 122
Query: 304 ELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYACNQFQPEWKVWEQYVA--DDLQSALGL 361
E+AH WFGN VT WE +WL+EG AT YA + E Y A L++A L
Sbjct: 123 EVAHSWFGNAVTNATWEEMWLSEGLAT----YAQRRI-----TTETYGAAFTCLETAFRL 173
Query: 362 DSL--------RSSHPIEVPVKRADEIN--QIFDHISYAKGSSLLRMISQWLGE-DVFVK 410
D+L S ++ VK +N + + +Y KG + +SQ G+ F
Sbjct: 174 DALHRQMKLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDD 233
Query: 411 GVSQYLNKFKFGNAKTEDLWDA 432
+ Y+ K+KF + +DL D+
Sbjct: 234 FLRAYVEKYKFTSVVAQDLLDS 255
>CE19614 [K] KOG1932 TATA binding protein associated factor
Length = 1086
Score = 55.5 bits (132), Expect = 4e-07
Identities = 78/373 (20%), Positives = 149/373 (39%), Gaps = 36/373 (9%)
Query: 139 ARRAFPCFDEPNLKASFEITLVSDPKLTHLSNMDV-KKEEIFDGKKFTY-FNPTPKMSTY 196
AR C DEP+ A +E+T +P L +++ ++ +K E+ + K Y F+ T S
Sbjct: 227 AREWTVCLDEPDQLALWELTFELEPHLVPVASGELEEKREVSENGKIRYKFHQTVPTSAC 286
Query: 197 LVAFIVAELEYVECKDFRIPVRVYATPGSEHLGQYAANLTAKTLSFFEKAFGIEYPLPKM 256
+ + + + +E + ++ PG E + K + F E+ +P P +
Sbjct: 287 NIGWAIGRFK-LEPHPESPTIYTFSLPGLEPFVNHTTMYLDKMVEFLEEKLSCRFPYPTL 345
Query: 257 DSVAVHEFSAGAMENWGLVTYRVVDLLLDEKNASLERIKRVAEVVQH-------ELAHQW 309
V V + + +V LL A L K++ +VVQ +A Q+
Sbjct: 346 KVVFVDQCTE---------EIQVYSSLLIVPTAMLYH-KKIIDVVQEARQKLIFSIALQF 395
Query: 310 FGNLVTMDWWEGLWLNEGFATWM-SWYACNQFQPEWKVWE-QYVADDL--------QSAL 359
FG L++ W W+ A ++ S Y + W+ + DD+ + L
Sbjct: 396 FGCLISPAQWWHWWIPVSIARFLTSLYVETKLGTAEARWQLKRAMDDVCDYEHQWGKIVL 455
Query: 360 GLDSLRSSHPIEVPVKRADEINQIFDHISYAKGSSLLRMISQWLGEDVFVKGVSQYLNKF 419
P+ V + + ++ KG +RM+ + +G + F++ + + L
Sbjct: 456 SPPEPTKKLPLHVDPRHEYTASPLYVEAMLKKGFLTMRMLQRRIGLEPFMRVLHRVLTVG 515
Query: 420 KFGNAK--TEDLWDALSEASGKDVRNVMDIWTKKV-GFPIVSVTEDGH---KITFKQNRY 473
+ K T W L + R+V+ + K++ F V GH + F NR
Sbjct: 516 LDMSEKKTTPAAWRHLLTTTESFFRSVISVTGKEIPSFLSQFVRTGGHAAFAVKFDFNRK 575
Query: 474 LNTADVKPEEDKT 486
N +++ ++D T
Sbjct: 576 RNIVEIEIKQDDT 588
>Hs21361893 [IOVE] KOG1047 Bifunctional leukotriene A4 hydrolase/aminopeptidase
LTA4H
Length = 529
Score = 54.3 bits (129), Expect = 8e-07
Identities = 45/184 (24%), Positives = 75/184 (40%), Gaps = 35/184 (19%)
Query: 303 HELAHQWFGNLVTMDWWEGLWLNEGFATWMS---WYACNQFQPEWKVWEQYVADDLQSAL 359
HE+AH WFG + W WL+EGFAT + W Q P +E +L++ L
Sbjct: 189 HEIAHAWFGLAIGARDWTEEWLSEGFATHLEDVFWATAQQLAP----YEAREQQELRACL 244
Query: 360 GLDSLRSS---HPIEVPVKRADE-------------------INQIFDHISYAKGSSLLR 397
L+ P E+ V R + +IF + Y KG LLR
Sbjct: 245 RWRRLQDEMQCSPEEMQVLRPSKDKTGHTSDSGASVIKHGLNPEKIFMQVHYLKGYFLLR 304
Query: 398 MISQWLGEDVFVKGVSQYLNKFKFGNAKTEDLWDALSEASGKD------VRNVMDIWTKK 451
+++ LG++ + + ++++ F ++D L E ++ V N+ W +
Sbjct: 305 FLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKRLELSVENIYQDWLES 364
Query: 452 VGFP 455
G P
Sbjct: 365 SGIP 368
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,390,221
Number of Sequences: 60738
Number of extensions: 2210174
Number of successful extensions: 5687
Number of sequences better than 1.0e-05: 60
Number of HSP's better than 0.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 5326
Number of HSP's gapped (non-prelim): 90
length of query: 859
length of database: 30,389,216
effective HSP length: 115
effective length of query: 744
effective length of database: 23,404,346
effective search space: 17412833424
effective search space used: 17412833424
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)