ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2901 good R KOG3195 General function prediction only Uncharacterized membrane protein NPD008/CGI-148
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII2901 1021002 1020418 -195
(195 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR084c [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148 223 1e-58
SPBC2A9.05c [R] KOG3195 Uncharacterized membrane protein NPD008/... 104 7e-23
7295016 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148 96 4e-20
At1g09330 [R] KOG3195 Uncharacterized membrane protein NPD008/CG... 95 5e-20
CE06925 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148 93 3e-19
Hs7705644 [R] KOG3195 Uncharacterized membrane protein NPD008/CG... 87 1e-17
Hs22067998 [R] KOG3195 Uncharacterized membrane protein NPD008/C... 79 4e-15
Hs21945058 [R] KOG3195 Uncharacterized membrane protein NPD008/C... 72 6e-13
Hs15311232 [R] KOG3195 Uncharacterized membrane protein NPD008/C... 72 6e-13
>YDR084c [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 199
Score = 223 bits (569), Expect = 1e-58
Identities = 112/200 (56%), Positives = 133/200 (66%), Gaps = 8/200 (4%)
Query: 1 MDSARNFYKTILASSHPLILTIHLLGKAVPIVFYLLGSWFLSSTVQFIIVILTLAADFYF 60
MD ARNFY TIL SSHPL+L+ HL GKAVPIVFY++GS FL+ T QFI V+L L+ DFY
Sbjct: 1 MDQARNFYNTILKSSHPLLLSFHLAGKAVPIVFYIIGSMFLNFTPQFITVVLLLSFDFYL 60
Query: 61 TKNINGRKLIQQRWWYDVSG-EDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPT 119
TKNI GRKL+Q RWWYD + + F FES+K+Y PIN IDSKLFW S+YV P
Sbjct: 61 TKNITGRKLVQLRWWYDSTDVNKDSNFTFESYKQY--APGPPINAIDSKLFWWSMYVTPV 118
Query: 120 IWVVFGFLCLIKFQFVYLILVIFAGGLNLWNAYAYRLCDQWEPGHTAE-----APLFQLP 174
IW VF LCL++ + YLILVI A L WN Y +R CD+WEP F LP
Sbjct: 119 IWGVFAVLCLLRLKIFYLILVIVAMCLTAWNTYGFRCCDRWEPNSGQSDGQDTNNWFALP 178
Query: 175 MLPSFANLDRVTRLQSFFTR 194
+P F NL R+ +QSFF R
Sbjct: 179 SVPGFENLSRLANIQSFFQR 198
>SPBC2A9.05c [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 219
Score = 104 bits (260), Expect = 7e-23
Identities = 58/147 (39%), Positives = 84/147 (56%), Gaps = 6/147 (4%)
Query: 14 SSHPLILTIHLLGKAVPIVFYLLGSWFLSSTVQFIIVILTL-AADFYFTKNINGRKLIQQ 72
SSHP+ L LL + IV Y+LG +F SS + IVI TL A D + KN++GR L+
Sbjct: 45 SSHPVALFFFLLFRTGAIVAYILGMFFTSSFMLLFIVIFTLLAVDLWTVKNVSGRLLVGL 104
Query: 73 RWWYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPTIWVVFGFLCLIKF 132
RW + + + + FES + P N +D K FW +LY+ P IW++ G + +I+F
Sbjct: 105 RWRNETGVDGESIWIFESADP-----SRPRNAVDQKTFWYALYLYPFIWIILGIVAIIRF 159
Query: 133 QFVYLILVIFAGGLNLWNAYAYRLCDQ 159
+F++L LV A GL N AY CD+
Sbjct: 160 EFLWLALVAVAIGLTSVNTAAYSRCDK 186
>7295016 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 215
Score = 95.5 bits (236), Expect = 4e-20
Identities = 49/145 (33%), Positives = 76/145 (51%), Gaps = 8/145 (5%)
Query: 15 SHPLILTIHLLGKAVPIVFYLLGSWFLSSTV-QFIIVILTLAADFYFTKNINGRKLIQQR 73
+HP + HL + I+ Y+ WF S + F+ V+L L+ADF+ KNI+GR L+ R
Sbjct: 33 THPYVTFFHLFFRGAAILIYMFCGWFSDSFITSFVFVVLFLSADFWTVKNISGRLLVGLR 92
Query: 74 WWYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPTIWVVFGFLCLIKFQ 133
WW V + + + FES + +N + ++FWL L + P W +F L +
Sbjct: 93 WWNYVDDDGVSHWVFES-------KNSRVNKNEQRIFWLGLILCPVFWGLFFLFALFGLK 145
Query: 134 FVYLILVIFAGGLNLWNAYAYRLCD 158
F +L+LV+ A LN N Y Y C+
Sbjct: 146 FKWLLLVMIAIALNAANLYGYVKCN 170
>At1g09330 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 186
Score = 95.1 bits (235), Expect = 5e-20
Identities = 50/158 (31%), Positives = 83/158 (51%), Gaps = 4/158 (2%)
Query: 1 MDSARNFYKTILASSHPLILTIHLLGKAVPIVFYLLGSWFLSS-TVQFIIVILTLAADFY 59
MD + ++P H+L K + FY+L + F +S + F++ +L A DF+
Sbjct: 1 MDPNNQIQAPVENYANPRTCLFHVLFKGAALAFYILSALFFNSFVIIFVVTVLLAALDFW 60
Query: 60 FTKNINGRKLIQQRWWYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPT 119
KN++GR L+ RWW +++ + ++FES + + A +N DS LFW +LY+A
Sbjct: 61 VVKNVSGRILVGLRWWNEINDLGESVWKFESLDQE---SLARMNKKDSWLFWWTLYLAAA 117
Query: 120 IWVVFGFLCLIKFQFVYLILVIFAGGLNLWNAYAYRLC 157
W + G LI+FQ YL++V LN+ N + C
Sbjct: 118 AWFILGVFSLIRFQADYLLVVGVCLSLNVANIIGFTKC 155
>CE06925 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 247
Score = 92.8 bits (229), Expect = 3e-19
Identities = 46/142 (32%), Positives = 74/142 (51%), Gaps = 6/142 (4%)
Query: 17 PLILTIHLLGKAVPIVFYLLGSWFLSS-TVQFIIVILTLAADFYFTKNINGRKLIQQRWW 75
P I+ HL K + FY ++F +S VQF++++ L+ DF+ KNI GR L+ RWW
Sbjct: 73 PTIVLAHLSFKGAALFFYFFANFFTNSFIVQFLVILTLLSMDFWTVKNITGRLLVGLRWW 132
Query: 76 YDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPTIWVVFGFLCLIKFQFV 135
V + ++FES K+ A ID ++FWL L V P W+ F + +F
Sbjct: 133 NFVDADGNNHWKFESAKDMTRFAT-----IDRRVFWLGLVVGPAAWIFFVVTAFLTLKFE 187
Query: 136 YLILVIFAGGLNLWNAYAYRLC 157
++I+ + +N+ N + Y C
Sbjct: 188 WMIVALLGALMNMANLWGYLRC 209
>Hs7705644 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 181
Score = 87.4 bits (215), Expect = 1e-17
Identities = 47/143 (32%), Positives = 73/143 (50%), Gaps = 2/143 (1%)
Query: 16 HPLILTIHLLGKAVPIVFYLLGSWFLSSTVQFII-VILTLAADFYFTKNINGRKLIQQRW 74
HP+ HL + I+ YLL SS + ++ +IL L+ DF+ KN+ GR ++ RW
Sbjct: 33 HPVASFFHLFFRVSAIIVYLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRW 92
Query: 75 WYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPTIWVVFGFLCLIKFQF 134
W + + + + FES KE ++ +S++FWL L P +WV+F F L F+
Sbjct: 93 WNHIDEDGKSHWVFESRKESSQENKT-VSEAESRIFWLGLIACPVLWVIFAFSALFSFRV 151
Query: 135 VYLILVIFAGGLNLWNAYAYRLC 157
+L +VI L N Y Y C
Sbjct: 152 KWLAVVIMGVVLQGANLYGYIRC 174
>Hs22067998 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 153
Score = 79.0 bits (193), Expect = 4e-15
Identities = 39/109 (35%), Positives = 60/109 (54%), Gaps = 2/109 (1%)
Query: 49 IVILTLAADFYFTKNINGRKLIQQRWWYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSK 108
+V+L L+ DF+ KN+ GR L+ RWW + + + + FE+ K P+ AA +++
Sbjct: 1 MVLLLLSLDFWSVKNVTGRLLVGLRWWNQIDEDGKSHWIFEARKVSPNSIAA--TEAEAR 58
Query: 109 LFWLSLYVAPTIWVVFGFLCLIKFQFVYLILVIFAGGLNLWNAYAYRLC 157
+FWL L + P IW+VF F L + +L LV+ L N Y Y LC
Sbjct: 59 IFWLGLIICPMIWIVFFFSTLFSLKLKWLALVVAGISLQAANLYGYILC 107
>Hs21945058 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 276
Score = 71.6 bits (174), Expect = 6e-13
Identities = 38/123 (30%), Positives = 62/123 (49%), Gaps = 2/123 (1%)
Query: 16 HPLILTIHLLGKAVPIVFYLLGSWFLSSTVQFII-VILTLAADFYFTKNINGRKLIQQRW 74
HP+ HL + I+ LL SS + ++ +IL L+ DF+ KN+ GR ++ RW
Sbjct: 33 HPVASFFHLFFRVSAIIVCLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRW 92
Query: 75 WYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPTIWVVFGFLCLIKFQF 134
W + + + + FES KE ++ +S++FWL L +WV+F F L F
Sbjct: 93 WNHIDEDGKSHWVFESRKE-SSQENKTVSEAESRIFWLGLIACSVLWVIFAFSALFSFTV 151
Query: 135 VYL 137
+L
Sbjct: 152 KWL 154
>Hs15311232 [R] KOG3195 Uncharacterized membrane protein NPD008/CGI-148
Length = 276
Score = 71.6 bits (174), Expect = 6e-13
Identities = 38/123 (30%), Positives = 62/123 (49%), Gaps = 2/123 (1%)
Query: 16 HPLILTIHLLGKAVPIVFYLLGSWFLSSTVQFII-VILTLAADFYFTKNINGRKLIQQRW 74
HP+ HL + I+ LL SS + ++ +IL L+ DF+ KN+ GR ++ RW
Sbjct: 33 HPVASFFHLFFRVSAIIVCLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRW 92
Query: 75 WYDVSGEDTTTFRFESFKEYPDVAAAPINPIDSKLFWLSLYVAPTIWVVFGFLCLIKFQF 134
W + + + + FES KE ++ +S++FWL L +WV+F F L F
Sbjct: 93 WNHIDEDGKSHWVFESRKE-SSQENKTVSEAESRIFWLGLIACSVLWVIFAFSALFSFTV 151
Query: 135 VYL 137
+L
Sbjct: 152 KWL 154
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.330 0.143 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,715,245
Number of Sequences: 60738
Number of extensions: 479429
Number of successful extensions: 1282
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1260
Number of HSP's gapped (non-prelim): 9
length of query: 195
length of database: 30,389,216
effective HSP length: 101
effective length of query: 94
effective length of database: 24,254,678
effective search space: 2279939732
effective search space used: 2279939732
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)