ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII2999 suspect: LH U KOG2063 Intracellular trafficking, secretion, and vesicular transport Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= r_klactIII2999 1051312  1053927 872  
         (872 letters)

Database: KOG eukaryal database 04/03 
           60,738 sequences; 30,389,216 total letters

Searching..................................................done

Color Key for Alignment Scores:   


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

YDR495c_2 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/V...   363   e-100

>YDR495c_2 [U] KOG2063 Vacuolar assembly/sorting proteins VPS39/VAM6/VPS3
          Length = 865

 Score =  363 bits (933), Expect = e-100
 Identities = 239/871 (27%), Positives = 445/871 (50%), Gaps = 51/871 (5%)

Query: 37  SCIEYYGQHIYLGSTSGALLHYYELDVGNFTLISEVNFNEDRPTGIDGITLLPKIDRALV 96
           +C E Y  HI+LG+T+G LLHY+EL+ GN+ L+S+  F+ +  + ID I LLPK++ AL+
Sbjct: 1   TCCEAYENHIFLGTTTGDLLHYFELERGNYMLVSQTKFDAESNSKIDKILLLPKVEGALI 60

Query: 97  LSEGRLKMFLLPEFAPASNIPSIMNITELSLLEFCEKTQCYSCFLYTKNLVKRVSITSKE 156
           L +  L +F+LPEFAP  N   +  I+++ +  F   ++ Y  + +    V+ + I++  
Sbjct: 61  LCDNELVLFILPEFAPRPNTTRLKGISDVVICNFSRSSKAYRIYAFHAEGVRLLKISADS 120

Query: 157 IKVEQKYNIKRIRKAIPSKDAKLLMAAVDNSYSIIHLENELVTPLFKVSETDDEELSPIV 216
           + + + +N K I KA   ++   LM +  NSY +I+L++  V PLF++SET DE+L PI+
Sbjct: 121 LVLTKAFNFKLIDKACAHEET--LMVSKLNSYELINLKSSQVIPLFRISET-DEDLEPII 177

Query: 217 TNFGKSEYIVTC--GISNDQNCMGLILNDDGEITHGTVVIENYPLTVIVDNLYVLSELHG 274
           T+F +    + C  G S D   M L++N  G+I  GT+V++NYP  VIV+  Y+++E   
Sbjct: 178 TSFNEQSEFLVCSGGGSYDSGAMALVVNHHGDIIKGTIVLKNYPRNVIVEFPYIIAE-SA 236

Query: 275 SKCLQIHLIKENNDPVVIQNVRNQ-TPFHITKLQTPFI----TRQFNKELIEKLRYVPLI 329
            + + I+    +    ++Q++    +   I+K    F     + +F +++  KLR  PL 
Sbjct: 237 FQSVDIYSALPSEKSQLLQSITTSGSDLKISKSDNVFTNTNNSEEFKEKIFNKLRLEPLT 296

Query: 330 AEELQFREEQEKAYVARQIAVECHMIIYGKCGIYSLCRKPFLLTISSYGE---DTLPILK 386
             + +FR E+E+A+V      +  +I+Y   GI+ L   P +L  +S  E   D +    
Sbjct: 297 HSDNKFRIERERAFVEESYEEKTSLIVYNNLGIHLLVPTPMVLRFTSCEESEIDNIEDQL 356

Query: 387 SFITEESQSNYQLLQKSYXXXXXXXXXXXHMEHIDKDLIDAWLKYIDVADIRVLIYLLGF 446
             + ++  + ++ ++  Y           H +HI+ +++  W  + D  DIR+L Y+ G+
Sbjct: 357 KKLAKKDLTKFEHIEAKYLMSLLLFLMTLHYDHIEDEVMKKWCDFSDKVDIRILFYMFGW 416

Query: 447 DIYGDLWIPNGLLAFXXXXXXXXXXXXCNDVLNIIQYLKFQLKETCSDSL--KDSANVYL 504
            +Y ++W  +GL+              C ++L ++  +K +LK+     L   D  ++  
Sbjct: 417 KVYSEIWCFHGLINIVERLKSLKLTNKCENILKMLLMMKNELKKKNKTGLLTNDFDDIMK 476

Query: 505 SLDLILLRDNIAKGSS-NVDEYEATSYQEIAXXXXXXXXX--XXXTLIAIYEKTKEVTPL 561
           ++D+ L +  + K  +  VD +E  SY EI                LI IY++  E    
Sbjct: 477 TIDITLFKLRLEKKETITVDMFERESYDEIIREINLHDDKLPRIELLIEIYKEKGEYLKA 536

Query: 562 LEILRQT-DQKRLINYLNTHFQELPDTYSKEMLTDDISSALKDYNDDT----VSDVLQLI 616
           L +LR+  D   L++++  + ++LP+ Y KE + DD+   LK  +++T    +  VL+++
Sbjct: 537 LNLLREAGDYISLVSFIEENLKKLPEDYIKERIADDLLLTLKQGDENTEECAIKKVLKIL 596

Query: 617 NNLNLDVKRLISSI--EDPDTKVLLLEKLGASSTQDLTFLYEYYKAKLTVLNSKLIESSN 674
           +   ++    ++ I  E+   KV  +E+LG  ++ D  FL+ YY AKL     ++I  SN
Sbjct: 597 DMACINKNDFLNKIPAEETSLKVSFIEQLGVQNSNDSKFLFNYYLAKL----REIINQSN 652

Query: 675 L------PITEYITNMTYNKSPFKEYLKNKLGE-------KKEYEGCFDVGTKLLKIEKA 721
           +       I EY  +  Y+K+    ++  KL          K YE C ++ ++  K ++ 
Sbjct: 653 IWSILGDFIKEYKDDFAYDKTDITNFIHIKLKHSLQCENFSKYYEKCENLKSENEKDDEF 712

Query: 722 LNIKEGSIIDDIDASFVLRIMITDISVLKEKIGFEKLLDIYLSRNDFATVESLLQANDKV 781
           +N      I  ID   +L ++    + L   +  E+LL IYLS NDF +VE  +   + V
Sbjct: 713 INFTFDE-ISKIDKEHILTLLFFP-NELTNWVSSEELLKIYLSFNDFRSVEKYIGKQNLV 770

Query: 782 VLKVIDHYLSLN----NTRVISQFLNKNTCCINDSGLLIEILEKIPPTIQISVLSGFLFP 837
              V+  YL ++    +  +++  L +N   ++D+ + ++ILE IP    +  +S  L  
Sbjct: 771 A--VMKQYLDISSLNYSVELVTNLLQRNFELLDDTDIQLKILETIPSVFPVQTISELLLK 828

Query: 838 LLRRKDESTYNLQIKKGILRHRTQNINNIER 868
           +L +  E      ++K +L+++    + + R
Sbjct: 829 VLIKYQEKKEESNLRKCLLKNQISISDELSR 859


  Database: KOG eukaryal database 04/03
    Posted date:  Apr 14, 2003  1:07 PM
  Number of letters in database: 30,389,216
  Number of sequences in database:  60,738
  
Lambda     K      H
   0.319    0.138    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,215,432
Number of Sequences: 60738
Number of extensions: 2122755
Number of successful extensions: 5863
Number of sequences better than 1.0e-05: 1
Number of HSP's better than  0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 5853
Number of HSP's gapped (non-prelim): 1
length of query: 872
length of database: 30,389,216
effective HSP length: 115
effective length of query: 757
effective length of database: 23,404,346
effective search space: 17717089922
effective search space used: 17717089922
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)