ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3021 check: MH T KOG0592 Signal transduction mechanisms 3-phosphoinositide-dependent protein kinase (PDK1)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3021 1060167 1062941 925
(925 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 488 e-137
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 488 e-137
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 310 9e-84
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 279 2e-74
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 259 1e-68
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 252 2e-66
7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 224 5e-58
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 215 2e-55
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 214 4e-55
CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 209 2e-53
CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 208 3e-53
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 192 2e-48
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 173 1e-42
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 171 5e-42
CE02604 [T] KOG0695 Serine/threonine protein kinase 171 6e-42
7300106 [T] KOG0690 Serine/threonine protein kinase 171 6e-42
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 169 2e-41
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 169 2e-41
At1g30640 [R] KOG0605 NDR and related serine/threonine kinases 169 2e-41
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 169 2e-41
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 168 3e-41
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 168 3e-41
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 168 4e-41
7301734 [T] KOG0694 Serine/threonine protein kinase 168 4e-41
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 167 7e-41
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 166 1e-40
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 166 2e-40
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 165 3e-40
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 165 3e-40
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 165 3e-40
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 165 3e-40
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 165 3e-40
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 165 3e-40
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 164 4e-40
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 164 4e-40
7302861 [T] KOG0696 Serine/threonine protein kinase 164 6e-40
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 164 6e-40
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 164 8e-40
At1g30270 [T] KOG0583 Serine/threonine protein kinase 164 8e-40
7301980 [D] KOG0608 Warts/lats-like serine threonine kinases 162 2e-39
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 162 2e-39
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 161 4e-39
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 161 4e-39
CE29092 [T] KOG0694 Serine/threonine protein kinase 161 4e-39
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 161 5e-39
CE02586 [T] KOG0696 Serine/threonine protein kinase 160 6e-39
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 160 1e-38
7302860 [T] KOG0696 Serine/threonine protein kinase 159 1e-38
At5g45810 [T] KOG0583 Serine/threonine protein kinase 159 2e-38
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 159 2e-38
At4g33080 [R] KOG0605 NDR and related serine/threonine kinases 159 2e-38
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 159 2e-38
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 158 3e-38
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 158 4e-38
At4g18700 [T] KOG0583 Serine/threonine protein kinase 157 5e-38
YPL209c [D] KOG0580 Serine/threonine protein kinase 157 7e-38
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 157 7e-38
Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases 157 7e-38
At1g29230 [T] KOG0583 Serine/threonine protein kinase 157 7e-38
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 157 9e-38
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 157 9e-38
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 157 9e-38
CE15612 [T] KOG0690 Serine/threonine protein kinase 157 9e-38
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 156 1e-37
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 156 1e-37
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 156 1e-37
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 156 2e-37
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 155 2e-37
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 155 2e-37
ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing pro... 155 2e-37
7303111 [T] KOG0695 Serine/threonine protein kinase 155 2e-37
7294770 [T] KOG0603 Ribosomal protein S6 kinase 155 2e-37
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 155 4e-37
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 154 6e-37
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 154 6e-37
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 154 6e-37
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 154 8e-37
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 154 8e-37
At2g25090 [T] KOG0583 Serine/threonine protein kinase 154 8e-37
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 153 1e-36
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 153 1e-36
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 153 1e-36
At4g14350 [R] KOG0605 NDR and related serine/threonine kinases 153 1e-36
YNR047w [R] KOG0610 Putative serine/threonine protein kinase 153 1e-36
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 153 1e-36
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 153 1e-36
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 153 1e-36
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 153 1e-36
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 153 1e-36
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 152 2e-36
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 152 2e-36
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 152 2e-36
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 152 2e-36
At3g23310 [R] KOG0605 NDR and related serine/threonine kinases 152 2e-36
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 152 2e-36
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 152 2e-36
CE24761 [D] KOG0580 Serine/threonine protein kinase 152 2e-36
Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases 152 3e-36
At2g45490 [D] KOG0580 Serine/threonine protein kinase 152 3e-36
At2g30360 [T] KOG0583 Serine/threonine protein kinase 152 3e-36
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 151 4e-36
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 151 4e-36
CE28760 [R] KOG0605 NDR and related serine/threonine kinases 151 4e-36
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 151 4e-36
At4g24400 [T] KOG0583 Serine/threonine protein kinase 151 4e-36
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 151 5e-36
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 151 5e-36
At5g09890 [R] KOG0605 NDR and related serine/threonine kinases 151 5e-36
At2g26980 [T] KOG0583 Serine/threonine protein kinase 151 5e-36
At2g20470 [R] KOG0605 NDR and related serine/threonine kinases 151 5e-36
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 151 5e-36
At1g03920 [R] KOG0605 NDR and related serine/threonine kinases 151 5e-36
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 150 9e-36
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 150 9e-36
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 150 1e-35
CE03979 [T] KOG0614 cGMP-dependent protein kinase 149 1e-35
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 149 2e-35
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 149 2e-35
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 149 2e-35
At1g01140 [T] KOG0583 Serine/threonine protein kinase 149 2e-35
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 149 3e-35
CE05274 [T] KOG0690 Serine/threonine protein kinase 149 3e-35
At5g58380 [T] KOG0583 Serine/threonine protein kinase 149 3e-35
At4g14580 [T] KOG0583 Serine/threonine protein kinase 149 3e-35
7295638 [T] KOG0603 Ribosomal protein S6 kinase 149 3e-35
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 148 3e-35
CE17354 [T] KOG0694 Serine/threonine protein kinase 148 3e-35
CE17353 [T] KOG0694 Serine/threonine protein kinase 148 3e-35
7293735 [R] KOG0605 NDR and related serine/threonine kinases 148 4e-35
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 148 4e-35
At5g01810 [T] KOG0583 Serine/threonine protein kinase 147 6e-35
At2g34180 [T] KOG0583 Serine/threonine protein kinase 147 6e-35
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 147 7e-35
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 147 1e-34
CE29298 [T] KOG0690 Serine/threonine protein kinase 147 1e-34
CE18646 [T] KOG0690 Serine/threonine protein kinase 147 1e-34
At5g45820 [T] KOG0583 Serine/threonine protein kinase 147 1e-34
7297611 [T] KOG0614 cGMP-dependent protein kinase 146 1e-34
SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases 145 2e-34
At4g30960 [T] KOG0583 Serine/threonine protein kinase 145 2e-34
YBL105c [T] KOG0694 Serine/threonine protein kinase 145 3e-34
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 145 3e-34
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 145 3e-34
At5g07070 [T] KOG0583 Serine/threonine protein kinase 145 3e-34
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 144 6e-34
At2g19400 [R] KOG0605 NDR and related serine/threonine kinases 144 8e-34
YGR092w [R] KOG0605 NDR and related serine/threonine kinases 142 2e-33
YNL161w [R] KOG0605 NDR and related serine/threonine kinases 142 2e-33
At5g35410 [T] KOG0583 Serine/threonine protein kinase 142 2e-33
CE19898 [T] KOG0614 cGMP-dependent protein kinase 142 3e-33
CE19897 [T] KOG0614 cGMP-dependent protein kinase 142 3e-33
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 141 4e-33
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 141 4e-33
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 140 7e-33
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 140 9e-33
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 140 9e-33
7303915 [T] KOG0694 Serine/threonine protein kinase 140 9e-33
7303914 [T] KOG0694 Serine/threonine protein kinase 140 9e-33
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 140 1e-32
At5g25110 [T] KOG0583 Serine/threonine protein kinase 139 2e-32
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 139 2e-32
YCL024w [T] KOG0583 Serine/threonine protein kinase 139 2e-32
At5g01820 [T] KOG0583 Serine/threonine protein kinase 139 2e-32
YDR122w [T] KOG0583 Serine/threonine protein kinase 139 3e-32
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 139 3e-32
At5g10930 [T] KOG0583 Serine/threonine protein kinase 139 3e-32
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 138 3e-32
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 138 3e-32
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 138 3e-32
At3g23000 [T] KOG0583 Serine/threonine protein kinase 138 3e-32
SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases 138 4e-32
CE21025 [D] KOG0580 Serine/threonine protein kinase 138 4e-32
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 138 4e-32
7296166 [T] KOG0614 cGMP-dependent protein kinase 138 4e-32
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 138 4e-32
CE27768 [R] KOG0586 Serine/threonine protein kinase 137 6e-32
CE23838 [R] KOG0586 Serine/threonine protein kinase 137 6e-32
At1g48260 [T] KOG0583 Serine/threonine protein kinase 137 8e-32
7302570 [R] KOG0586 Serine/threonine protein kinase 137 8e-32
YPR111w [R] KOG0605 NDR and related serine/threonine kinases 137 1e-31
SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase 137 1e-31
At4g32830 [D] KOG0580 Serine/threonine protein kinase 136 1e-31
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 136 2e-31
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 136 2e-31
SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase 135 2e-31
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 135 2e-31
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 135 4e-31
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 134 5e-31
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 134 5e-31
7299438 [R] KOG0586 Serine/threonine protein kinase 134 5e-31
7290249 [R] KOG0586 Serine/threonine protein kinase 134 6e-31
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 134 8e-31
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 134 8e-31
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 134 8e-31
At3g29160 [T] KOG0583 Serine/threonine protein kinase 134 8e-31
7299536 [D] KOG0580 Serine/threonine protein kinase 134 8e-31
SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases 133 1e-30
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 133 1e-30
At5g57630 [T] KOG0583 Serine/threonine protein kinase 133 1e-30
At2g25880 [D] KOG0580 Serine/threonine protein kinase 133 1e-30
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 133 1e-30
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 132 2e-30
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 132 2e-30
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 132 2e-30
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 132 2e-30
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 2e-30
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 132 2e-30
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 2e-30
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 132 3e-30
At5g39440 [T] KOG0583 Serine/threonine protein kinase 132 3e-30
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 132 3e-30
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 131 4e-30
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 131 4e-30
At3g17510 [T] KOG0583 Serine/threonine protein kinase 131 4e-30
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 131 5e-30
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 131 5e-30
CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases 131 5e-30
At3g01090 [T] KOG0583 Serine/threonine protein kinase 131 5e-30
7299437 [R] KOG0586 Serine/threonine protein kinase 131 5e-30
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 130 7e-30
At2g38490 [T] KOG0583 Serine/threonine protein kinase 130 7e-30
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 130 9e-30
HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related... 130 9e-30
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 130 9e-30
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 130 9e-30
7303211 [T] KOG4717 Serine/threonine protein kinase 130 9e-30
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 130 9e-30
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 130 1e-29
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 130 1e-29
7290150 [T] KOG0583 Serine/threonine protein kinase 130 1e-29
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 129 2e-29
At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 129 2e-29
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 129 2e-29
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 129 2e-29
7294217 [D] KOG0588 Serine/threonine protein kinase 129 2e-29
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 129 3e-29
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 129 3e-29
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 129 3e-29
7302464 [R] KOG0586 Serine/threonine protein kinase 129 3e-29
7297776 [D] KOG0580 Serine/threonine protein kinase 129 3e-29
YDR507c [D] KOG0588 Serine/threonine protein kinase 128 4e-29
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 128 4e-29
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 128 4e-29
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 128 5e-29
CE00847 [T] KOG0583 Serine/threonine protein kinase 127 6e-29
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 127 8e-29
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 127 8e-29
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 127 8e-29
CE18699 [T] KOG0694 Serine/threonine protein kinase 126 1e-28
At3g20860 [R] KOG0589 Serine/threonine protein kinase 126 1e-28
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 1e-28
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 126 1e-28
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 126 2e-28
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 126 2e-28
CE17284 [T] KOG0583 Serine/threonine protein kinase 126 2e-28
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 125 2e-28
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 3e-28
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 125 3e-28
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 125 4e-28
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 125 4e-28
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 125 4e-28
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 4e-28
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 125 4e-28
YLR096w [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 5e-28
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 124 5e-28
7297080 [T] KOG0583 Serine/threonine protein kinase 124 5e-28
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 7e-28
Hs4885349 [T] KOG0986 G protein-coupled receptor kinase 124 9e-28
YKL101w [D] KOG0588 Serine/threonine protein kinase 123 1e-27
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 1e-27
At1g50700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 123 1e-27
YDR477w [T] KOG0583 Serine/threonine protein kinase 123 1e-27
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 123 1e-27
7294265 [TR] KOG0606 Microtubule-associated serine/threonine kin... 123 1e-27
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 122 2e-27
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 122 2e-27
CE21239 [T] KOG0583 Serine/threonine protein kinase 122 2e-27
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 2e-27
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 122 3e-27
CE16081 [T] KOG0583 Serine/threonine protein kinase 122 3e-27
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 122 3e-27
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 121 4e-27
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 121 6e-27
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 120 7e-27
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 120 7e-27
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 120 7e-27
CE28218 [D] KOG0588 Serine/threonine protein kinase 120 7e-27
CE01554 [T] KOG0986 G protein-coupled receptor kinase 120 7e-27
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 120 7e-27
7299507 [T] KOG0607 MAP kinase-interacting kinase and related se... 120 7e-27
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 120 1e-26
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 120 1e-26
SPAC2C4.14c [T] KOG0201 Serine/threonine protein kinase 119 2e-26
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 119 2e-26
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
Hs4504101 [T] KOG0986 G protein-coupled receptor kinase 119 2e-26
CE28643 [T] KOG0583 Serine/threonine protein kinase 119 2e-26
CE07458 [T] KOG0583 Serine/threonine protein kinase 119 2e-26
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 2e-26
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 119 3e-26
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 118 4e-26
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 118 5e-26
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 118 5e-26
Hs4885347 [T] KOG0986 G protein-coupled receptor kinase 118 5e-26
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 118 5e-26
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 118 5e-26
At4g21940 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 5e-26
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 117 6e-26
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 117 6e-26
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 117 6e-26
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 6e-26
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 6e-26
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 6e-26
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 117 8e-26
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 8e-26
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 117 1e-25
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 116 1e-25
CE29300 [T] KOG0694 Serine/threonine protein kinase 116 2e-25
CE29299 [T] KOG0694 Serine/threonine protein kinase 116 2e-25
Hs8923754 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 115 2e-25
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 115 2e-25
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 3e-25
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 3e-25
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 115 3e-25
SPBC21.06c [T] KOG0198 MEKK and related serine/threonine protein... 115 4e-25
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 115 4e-25
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 5e-25
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 114 5e-25
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 114 7e-25
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 114 9e-25
CE28479 [T] KOG0583 Serine/threonine protein kinase 114 9e-25
CE02074 [T] KOG0986 G protein-coupled receptor kinase 114 9e-25
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 113 1e-24
CE18454 [T] KOG4717 Serine/threonine protein kinase 113 1e-24
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 113 1e-24
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 113 2e-24
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 2e-24
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 113 2e-24
7300413 [T] KOG0583 Serine/threonine protein kinase 113 2e-24
YOR233w [T] KOG0583 Serine/threonine protein kinase 112 2e-24
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
Hs4885055 [T] KOG0986 G protein-coupled receptor kinase 112 2e-24
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 112 2e-24
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 112 2e-24
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 112 2e-24
SPCC297.03 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 112 3e-24
Hs9994197 [T] KOG0607 MAP kinase-interacting kinase and related ... 112 3e-24
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 112 3e-24
YPL150w [T] KOG0583 Serine/threonine protein kinase 111 4e-24
YHR102w [T] KOG0201 Serine/threonine protein kinase 111 4e-24
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 111 4e-24
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 111 4e-24
CE23524 [T] KOG1151 Tousled-like protein kinase 111 4e-24
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 111 4e-24
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 111 4e-24
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 111 4e-24
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 111 4e-24
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 111 6e-24
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 110 8e-24
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 110 8e-24
At1g54510 [R] KOG0589 Serine/threonine protein kinase 110 8e-24
CE17343 [T] KOG0583 Serine/threonine protein kinase 110 1e-23
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 110 1e-23
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 110 1e-23
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 110 1e-23
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 110 1e-23
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 110 1e-23
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 110 1e-23
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 109 2e-23
SPCC1450.11c [R] KOG0605 NDR and related serine/threonine kinases 109 2e-23
Hs4501971 [T] KOG0986 G protein-coupled receptor kinase 109 2e-23
CE03584 [T] KOG0607 MAP kinase-interacting kinase and related se... 109 2e-23
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 109 2e-23
7299793 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 109 2e-23
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 109 2e-23
7302050 [T] KOG0986 G protein-coupled receptor kinase 109 2e-23
Hs7661994 [T] KOG0579 Ste20-like serine/threonine protein kinase 108 3e-23
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 108 3e-23
YLR362w [T] KOG0198 MEKK and related serine/threonine protein ki... 108 4e-23
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 4e-23
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 108 4e-23
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 108 4e-23
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 108 5e-23
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 107 6e-23
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 107 6e-23
At3g57530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 6e-23
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 107 6e-23
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 107 8e-23
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 107 8e-23
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 107 1e-22
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 1e-22
CE18366 [T] KOG0583 Serine/threonine protein kinase 107 1e-22
7300437 [TR] KOG0606 Microtubule-associated serine/threonine kin... 107 1e-22
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 106 1e-22
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 106 1e-22
At5g28290 [R] KOG0589 Serine/threonine protein kinase 106 1e-22
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 1e-22
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 106 2e-22
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 106 2e-22
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 106 2e-22
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 106 2e-22
CE07905 [T] KOG0579 Ste20-like serine/threonine protein kinase 106 2e-22
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 106 2e-22
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 106 2e-22
Hs21166359 [T] KOG0986 G protein-coupled receptor kinase 105 2e-22
7296128 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 105 2e-22
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 105 2e-22
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 105 3e-22
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 105 3e-22
HsM4758524 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 105 3e-22
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 105 3e-22
Hs22035606 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 105 3e-22
Hs22035604 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 105 3e-22
Hs22035602 [T] KOG0587 Traf2- and Nck-interacting kinase and rel... 105 3e-22
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 105 3e-22
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 3e-22
At3g04810 [R] KOG0589 Serine/threonine protein kinase 105 3e-22
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 105 3e-22
CE23001 [R] KOG0589 Serine/threonine protein kinase 105 4e-22
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 105 4e-22
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 104 5e-22
HsM5729922 [T] KOG0198 MEKK and related serine/threonine protein... 104 5e-22
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 104 5e-22
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 104 7e-22
Hs7657335 [T] KOG0587 Traf2- and Nck-interacting kinase and rela... 104 7e-22
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 104 7e-22
CE27177 [T] KOG4279 Serine/threonine protein kinase 104 7e-22
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 103 9e-22
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 103 9e-22
YFL033c [R] KOG0605 NDR and related serine/threonine kinases 103 1e-21
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 103 1e-21
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 103 1e-21
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 103 2e-21
7292249 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 103 2e-21
YBR274w [D] KOG0590 Checkpoint kinase and related serine/threoni... 102 2e-21
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 102 2e-21
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 102 2e-21
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 102 2e-21
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 102 2e-21
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 102 3e-21
Hs21735556 [T] KOG0198 MEKK and related serine/threonine protein... 102 4e-21
At1g03740 [D] KOG0600 Cdc2-related protein kinase 102 4e-21
YPL141c [T] KOG0583 Serine/threonine protein kinase 101 5e-21
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 101 5e-21
CE29020 [T] KOG0660 Mitogen-activated protein kinase 101 5e-21
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 101 5e-21
At4g08470 [T] KOG0198 MEKK and related serine/threonine protein ... 101 5e-21
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 5e-21
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 101 5e-21
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 101 5e-21
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 101 6e-21
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 101 6e-21
7291778 [T] KOG0579 Ste20-like serine/threonine protein kinase 101 6e-21
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 100 8e-21
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 100 8e-21
Hs5902140_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 100 8e-21
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 100 1e-20
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 100 1e-20
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 1e-20
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 100 1e-20
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 100 1e-20
At5g14720 [T] KOG0582 Ste20-like serine/threonine protein kinase 100 1e-20
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 100 1e-20
7290147 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 100 1e-20
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 100 1e-20
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 1e-20
CE28273 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 100 1e-20
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 100 1e-20
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 100 1e-20
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 100 1e-20
CE25673 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 100 1e-20
CE25672 [T] KOG0587 Traf2- and Nck-interacting kinase and relate... 100 1e-20
At1g78290 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
7300224 [T] KOG0201 Serine/threonine protein kinase 100 1e-20
SPBC17F3.02 [T] KOG0201 Serine/threonine protein kinase 100 2e-20
Hs5454096 [T] KOG0574 STE20-like serine/threonine kinase MST 100 2e-20
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 100 2e-20
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 100 2e-20
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 100 2e-20
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 100 2e-20
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 100 2e-20
At4g08480 [T] KOG0198 MEKK and related serine/threonine protein ... 100 2e-20
7300288 [D] KOG0596 Dual specificity; serine/threonine and tyros... 100 2e-20
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 100 2e-20
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 488 bits (1256), Expect = e-137
Identities = 260/492 (52%), Positives = 346/492 (69%), Gaps = 38/492 (7%)
Query: 63 PVLTKALTDVDNFISL--DPKYLNRRNDSLSSV-------ETIDSTRD-------DNISI 106
P++ KALT+ DNFI + + + N +D++ V +T+ ST D DN I
Sbjct: 67 PMIQKALTNTDNFIEMYHNQQRKNLDDDTIKEVMINDENGKTVASTNDGRYDNDYDNNDI 126
Query: 107 PKELPI-----SESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETL 161
+ + S M++ + + + K + K++ K K +IKKGI DFKFG +
Sbjct: 127 NDQKTLDNIAGSPHMEKNRNKVKIEHDSSSQKPIA-KESSKAQKNIIKKGIKDFKFGSVI 185
Query: 162 GDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYF 221
GDG+YSTV+LATSI++ K+YA K+LNKEYLI+QKKVKYV+IEK LQ+L N+ ++ L+
Sbjct: 186 GDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQKKVKYVSIEKTALQKLNNSPSVVRLFS 245
Query: 222 TFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLK 281
TFQDESSLYFLLEYAPNGD LSLM+K+GS++E C +YYAAQIIDA+ ++H G+IHRD+K
Sbjct: 246 TFQDESSLYFLLEYAPNGDFLSLMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIK 305
Query: 282 PENILLDVDMKVKLTDFGTARLLDSTSEDDLK--YDLLTRSNSFVGTAEYVSPELLNDNY 339
PENILLD +MK+KLTDFGTA+LL+ T+ K YDL TRS SFVGTAEYVSPELLND++
Sbjct: 306 PENILLDGEMKIKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAEYVSPELLNDSF 365
Query: 340 VDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILI 399
D+RCDIWAFGCILFQMIAGKPPFKA NEYLTFQKVMKVQ+AFT GFP+ +RDLVK IL+
Sbjct: 366 TDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFTPGFPLIIRDLVKKILV 425
Query: 400 KNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQ---SSVPKVASSP 456
KN +RRL I+QIK H FF D+NF +GSVW K PPE+ PYK++A+++Q S +
Sbjct: 426 KNLDRRLTISQIKEHHFFKDLNFKDGSVWSKTPPEIKPYKINAKSMQAMPSGSDRKLVKK 485
Query: 457 AINPI---HEPVRQSSVSPKITPKNTTTAQRPNGDTTSTT------TKRELDPRTQRILN 507
++N + H ++S+ SP + + TT + N +T ++T KR D RT +IL
Sbjct: 486 SVNTLGKSHLVTQRSASSPSV--EETTHSTLYNNNTHASTESEISIKKRPTDERTAQILE 543
Query: 508 NVKKEISQRNHR 519
N +K I+ R ++
Sbjct: 544 NARKGINNRKNQ 555
Score = 139 bits (351), Expect = 2e-32
Identities = 105/350 (30%), Positives = 164/350 (46%), Gaps = 49/350 (14%)
Query: 613 MSKLDIMWSYYLKNIQERVIKMGEINVTTLKNQSLEAKISKSKLSLLDADGRVQKKNTLL 672
M+K DI WS+YLKNI E V++ +++ T LE K+ K SLLD + ++T L
Sbjct: 689 MNKQDIQWSFYLKNINEHVLRTEKLDFVTTNYDILEKKMLKLNGSLLDPQLFGKPRHTFL 748
Query: 673 TQVVRGGGNVTGFRQENS----NLVEHDFYSEYLIDPENVEASYRKQSG----------- 717
+QV R GG VTGFR + + + E +YS+ +ID + +E YR + G
Sbjct: 749 SQVARSGGEVTGFRNDPTMTAYSKTEDTYYSKNIIDLQLLEDDYRIEGGDLSELLTNRSG 808
Query: 718 ----------------ADEASHEGMS----KLKHFFSKAPDAPAEFIAQSE----YIKRM 753
E++++G S K+K F P + AE ++ S+ Y KR
Sbjct: 809 EGYKCNQNSSPMKDDDKSESNNKGSSVFSGKIKKLFH--PTSAAETLSSSDEKTKYYKRT 866
Query: 754 CVITTFGRCLLFARKNKINQNSNLFYDLEYEIDLSQLGVRIKEVVPEKKTSSKDIFVVQT 813
V+T+FGR L+FA++ + N +NL Y+LEY+I+L Q G +IKE++ + + I V+QT
Sbjct: 867 IVMTSFGRFLVFAKRRQPNPVTNLKYELEYDINLRQQGTKIKELIIPLEMGTNHIVVIQT 926
Query: 814 PFKTFVFQTDESDTLVWLHSLTSAIKSKNERFTNNETSINPIANKXXXXXXXXXXXXXNG 873
P+K+F+ TD+ T L + S + N
Sbjct: 927 PYKSFLLSTDKKTTSKLFTVLKKILNSNTNKIEKELLQRN--QKVIERRTSSSGRAIPKD 984
Query: 874 YKTTKTPFLTKRRSSFTSQRQKQNNNGKLGTRPISSGSRMLSRSEQIFRT 923
T+K+P R S + K N+ + S S +RS +IF T
Sbjct: 985 LPTSKSPSPKPRTHSQSPSISKHNSFSE------SINSAKSNRSSRIFET 1028
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 488 bits (1256), Expect = e-137
Identities = 262/532 (49%), Positives = 345/532 (64%), Gaps = 63/532 (11%)
Query: 8 NKPIIPTSGSARSVMHRPTPPPIPMELSHPPLPTIRTTDDLSNLSEMKPFGKPNPPVLTK 67
+KP++PTS P P D ++ S + P K
Sbjct: 15 SKPLVPTSAEHTQTQEYPRP----------------FVDGSNSQSGSELQASPQGQFGEK 58
Query: 68 ALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRG 127
ALT + FI L +D+ + E+ + SM+RR++EWA+RG
Sbjct: 59 ALTSTNRFIPL---------------------ANDDPGMQHEMGLDPSMRRRREEWAERG 97
Query: 128 AAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILN 187
AA IVKDV D TG++TK V+K GI DFKFGE LGDGSYS+V+LAT+ +S KKYAVK+L+
Sbjct: 98 AAKIVKDVVDPATGELTKHVVKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLS 157
Query: 188 KEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRK 247
KEYLI+QKKVKYV +EK LQ+L TKGI L+FTFQDE+SLYFLLEYAP+GD L L++K
Sbjct: 158 KEYLIRQKKVKYVTVEKLALQKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKK 217
Query: 248 HGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLL--- 304
+GS+NE C +YYA+QIIDA+ +H+ G+IHRD+KPENILLD +MKVKLTDFGTA++L
Sbjct: 218 YGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEE 277
Query: 305 -DSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPF 363
+T++ +DL +S SFVGTAEYVSPELLNDNY D RCDIWAFGCIL+QM+AGKPPF
Sbjct: 278 PSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKPPF 337
Query: 364 KANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFG 423
KA NEYLTFQKVMK+Q+AFTAGFP V+DLVK +L+++P RL I QIKAH FF +VNF
Sbjct: 338 KAANEYLTFQKVMKIQYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFHEVNFE 397
Query: 424 NGSVWDKDPPELGPYKVSARALQ--------------SSVPKVASSPAINPIHEPVRQSS 469
+GSVWD +PPE+ PYK++A A++ +++ + A P+ P S
Sbjct: 398 DGSVWDDNPPEIQPYKINAEAMKPLQKVSESDTTVKMANLQLAGNGHADTPLQAPAATSQ 457
Query: 470 VSPKITPKNTTTA------QRPNGDTTSTTTKRELDPRTQRILNNVKKEISQ 515
I+ T A +P + S+T+ R T R + ++K++S+
Sbjct: 458 EHSVISMTAATAAFNKDYTSQPKLGSKSSTSVRSASNNTDREV--IQKKVSK 507
>SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 592
Score = 310 bits (793), Expect = 9e-84
Identities = 163/357 (45%), Positives = 227/357 (62%), Gaps = 13/357 (3%)
Query: 136 PDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQK 195
P+ +G T + K ++DFKFGE LG+GSYSTVL AT + ++YA+K+L+K ++IK+K
Sbjct: 82 PNPSSGASTPNI--KRVSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEK 139
Query: 196 KVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKC 255
K KYVNIEK L L G I L++TFQD +LYF+L A NG+LL + K G NE C
Sbjct: 140 KEKYVNIEKEALCILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEIC 199
Query: 256 TQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDS---TSEDDL 312
QYYAA I+D++ +MH +GVIHRDLKPENILLD +M+ K+TDFG+A++L+S + E+D
Sbjct: 200 AQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDT 259
Query: 313 KY--DLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYL 370
+ S SFVGTA YVSPE+L+D DIWAFGCILFQM+AGKPPF A NEYL
Sbjct: 260 HHADKPQAHSRSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYL 319
Query: 371 TFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDK 430
TFQ ++ + + DL+K +L+ +P+ RL +++I H FF + F N ++W+
Sbjct: 320 TFQSILHLSYEIPPDISDVASDLIKKLLVLDPKDRLTVDEIHQHPFFNGIKFDN-TLWEL 378
Query: 431 DPPELGPYKVSARALQSSVPKVASSPAINPIHEPVRQSSVSPKITPKNTTTAQRPNG 487
PP L P+ ++ L SVP ++ + P+ P + +T A P G
Sbjct: 379 PPPRLKPFGHTS-VLSLSVPNASNKHENGDLTSPLG----VPSMVSASTNAAPSPVG 430
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 279 bits (713), Expect = 2e-74
Identities = 141/296 (47%), Positives = 202/296 (67%), Gaps = 16/296 (5%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
KK DFKFG+ LG+GS+STV+LA + ++++YA+KIL K ++IK+ KV YV E++ +
Sbjct: 76 KKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMS 135
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
RL + + LYFTFQD+ LYF L YA NG+LL +RK GS +E CT++Y A+I+ AL
Sbjct: 136 RLDHPF-FVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALE 194
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
++H KG+IHRDLKPENILL+ DM +++TDFGTA++L S+ R+NSFVGTA+
Sbjct: 195 YLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQ-------ARANSFVGTAQ 247
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
YVSPELL + D+WA GCI++Q++AG PPF+A NEYL FQK++K+++ F F
Sbjct: 248 YVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFP 307
Query: 389 TVRDLVKNILIKNPERRLLINQ------IKAHQFFADVNFGNGSVWDKDPPELGPY 438
RDLV+ +L+ + +RL + +KAH FF V + N + + PP+L Y
Sbjct: 308 KARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWEN--LHQQTPPKLTAY 361
>SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 420
Score = 259 bits (663), Expect = 1e-68
Identities = 126/286 (44%), Positives = 189/286 (66%), Gaps = 4/286 (1%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
D+ FG+ +GDGS+S V AT +S K+YA+K+L+K+Y++K+ KVKYVNIE++++ RL
Sbjct: 53 DYVFGDIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGF 112
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
GI L+ TFQD+ LY++LE APNG+LL ++K+ ++E C ++YAA+I+ ++ +MH
Sbjct: 113 PGISRLFHTFQDDLKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMHSC 172
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
G+IHRDLKPENIL D +M VK+TDFGTA++L + Y T +SFVGTAEYV+PE
Sbjct: 173 GIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDY--TTFPSSFVGTAEYVAPE 230
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
LL+ V D+WAF C+++QMI G PPF +N F+K+M +++ P + L
Sbjct: 231 LLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIFKKIMSLEYELPKLLPPDIVPL 290
Query: 394 VKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYK 439
++ P R QIK FFA + + N +W +DPP + ++
Sbjct: 291 FSHLFRIQPSDRSTTQQIKQFPFFATITWDN--LWTQDPPPMQSFR 334
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 252 bits (643), Expect = 2e-66
Identities = 135/296 (45%), Positives = 195/296 (65%), Gaps = 20/296 (6%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIES-NKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
K+ +DF F E LG GSYSTV A +S NK YA+K+ +K+++IK+ KVKYV IEKNT+
Sbjct: 5 KRSPHDFIFKEELGHGSYSTVFKALDKKSPNKIYAIKVCSKKHIIKEAKVKYVTIEKNTM 64
Query: 208 QRL--KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIID 265
L K+ GII LY+TF DE +LYF+L++AP G+LLSL+ K G+ N+ T+++ AQ+ID
Sbjct: 65 NLLAQKHHAGIIKLYYTFHDEENLYFVLDFAPGGELLSLLHKMGTFNDIWTRHFTAQLID 124
Query: 266 ALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLD-STSEDDLKYDLLTRSN--- 321
AL F+H G+IHRDLKPEN+LLD D ++ +TDFG A +D S S D K++ + +
Sbjct: 125 ALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNGSKDN 184
Query: 322 ----SFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK 377
SFVGTAEYVSPELL N + DIWA GC+++Q + G+PPF+ NE TF+K++
Sbjct: 185 QNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVA 244
Query: 378 VQFAF---------TAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGN 424
+ + + T+ V +LV+ IL+ R+ + QIK H +F+ V++ +
Sbjct: 245 LDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERISLEQIKRHPYFSKVDWND 300
>7291910 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 755
Score = 224 bits (571), Expect = 5e-58
Identities = 130/416 (31%), Positives = 211/416 (50%), Gaps = 73/416 (17%)
Query: 86 RNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITK 145
+ND E +D R + + + Q++Q++ + + +Q ++
Sbjct: 104 QNDIRQQTEILDMLRQQHQQGYQSQQQQQQPQQQQEQQQQQEQS--------QQQQQLQN 155
Query: 146 QVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKN 205
++ NDF FG +G+GSYS V LA I S ++YA+K+ K +++++K Y+ E+
Sbjct: 156 PAPRRSPNDFIFGRYIGEGSYSIVYLAVDIHSRREYAIKVCEKRLILRERKQDYIKRERE 215
Query: 206 TLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIID 265
+ ++ N G ++L TFQD+ SLYF++ YA GD+L + + GS + CT++YAA+++
Sbjct: 216 VMHQMTNVPGFVNLSCTFQDQRSLYFVMTYARKGDMLPYINRVGSFDVACTRHYAAELLL 275
Query: 266 ALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLL-----------------DSTS 308
A MH + V+HRDLKPENILLD DM + DFG+A+++ ++
Sbjct: 276 ACEHMHRRNVVHRDLKPENILLDEDMHTLIADFGSAKVMTAHERALATEHCSEQRRSNSD 335
Query: 309 EDDLKYDLLT---------------------------------------RSNSFVGTAEY 329
EDD D L R SFVGTA+Y
Sbjct: 336 EDDEDSDRLENEDEDFYDRDSEELDDGDDEQQQEEMDSPRHRQRRYNRHRKASFVGTAQY 395
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
VSPE+L + + D+WA GCI++QMIAG PPF+ +N+Y+ F++++ F GF
Sbjct: 396 VSPEVLQNGPITPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGFDKD 455
Query: 390 VRDLVKNILIKNPERRL-------LINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
DLV+ +L +P RL I+AH FFA +++ ++ + PP + PY
Sbjct: 456 AEDLVRKLLRVDPRDRLGAQDEFGYYESIRAHPFFAGIDW--QTLRQQTPPPIYPY 509
>At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 488
Score = 215 bits (548), Expect = 2e-55
Identities = 130/373 (34%), Positives = 200/373 (52%), Gaps = 39/373 (10%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF+FG+ G GSYS V+ A E+ YA+KI++K+++ K+ K YV +E+ L +L++
Sbjct: 39 HDFEFGKIYGVGSYSKVVRAKKKETGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEH 98
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
GII LYFTFQD SSLY LE G+L + + G ++E ++Y A+++DAL ++H
Sbjct: 99 P-GIIKLYFTFQDTSSLYMALESCEGGELFDQITRKGRLSEDEARFYTAEVVDALEYIHS 157
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTAR--------LLDSTSEDDLKYDLLTRSNSFV 324
G+IHRD+KPEN+LL D +K+ DFG+ + +L + + DD ++ +FV
Sbjct: 158 MGLIHRDIKPENLLLTSDGHIKIADFGSVKPMQDSQITVLPNAASDD-------KACTFV 210
Query: 325 GTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTA 384
GTA YV PE+LN + F D+WA GC L+QM++G PFK +E+L FQ+++ F
Sbjct: 211 GTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPN 270
Query: 385 GFPMTVRDLVKNILIKNPERRLLINQ-----IKAHQFFADVNFGNGSVWDKDPPELGPYK 439
F RDL+ +L P RR +K H FF V++ N + + PP+L P
Sbjct: 271 HFSEAARDLIDRLLDTEPSRRPGAGSEGYVALKRHPFFNGVDWKN--LRSQTPPKLAPDP 328
Query: 440 VSARALQSSVPKVASSPAINPIH-EPVRQSSVSPKITPKN-----TTTAQRPNGDTTSTT 493
S A SP + H P + + + +N T+ +G T
Sbjct: 329 ASQTA----------SPERDDTHGSPWNLTHIGDSLATQNEGHSAPPTSSESSGSITRLA 378
Query: 494 TKRELDPRTQRIL 506
+ D R Q+ L
Sbjct: 379 SIDSFDSRWQQFL 391
>At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 483
Score = 214 bits (546), Expect = 4e-55
Identities = 127/387 (32%), Positives = 218/387 (55%), Gaps = 31/387 (8%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF+ G+ G GSYS V+ A ++ YA+KI++K+++ K+ K YV +E+ L +L++
Sbjct: 40 HDFELGKIYGVGSYSKVVRAKKKDNGTVYALKIMDKKFITKENKTAYVKLERIVLDQLEH 99
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
GI+ L+FTFQD SLY LE G+L + + G ++E ++Y+A+++DAL ++H+
Sbjct: 100 P-GIVKLFFTFQDTQSLYMALESCEGGELFDQITRKGRLSEDEARFYSAEVVDALEYIHN 158
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTAR--------LLDSTSEDDLKYDLLTRSNSFV 324
G+IHRD+KPEN+LL +D +K+ DFG+ + +L + + DD ++ +FV
Sbjct: 159 MGLIHRDIKPENLLLTLDGHIKIADFGSVKPMQDSQITVLPNAASDD-------KACTFV 211
Query: 325 GTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTA 384
GTA YV PE+LN + F D+WA GC L+QM++G PFK +E+L FQ+++ F
Sbjct: 212 GTAAYVPPEVLNSSPATFGNDLWALGCTLYQMLSGTSPFKDASEWLIFQRIIARDIKFPN 271
Query: 385 GFPMTVRDLVKNILIKNPERR-----LLINQIKAHQFFADVNFGNGSVWDKDPPELGPYK 439
F RDL+ +L +P RR + +K H FF V++ N + + PP+L P
Sbjct: 272 HFSEAARDLIDRLLDTDPSRRPGAGSEGYDSLKRHPFFKGVDWKN--LRSQTPPKLAPDP 329
Query: 440 VSARALQSSVPKVASSPAINPIH---EPVRQSSVSPKITPKNTTTAQRPNGDTTSTTTKR 496
S QS+ P+ SP NP H V Q+ ++ + + + + D+ + ++
Sbjct: 330 AS----QSASPERDGSP-WNPTHVGDTSVLQNDGHNGLSESSGSITRLASIDSFDSRWQQ 384
Query: 497 ELDPRTQRILNNVKKEISQRNHRRAAL 523
L+P ++ + K++ + ++ L
Sbjct: 385 FLEPGESVLMISAVKKLQKITSKKVQL 411
>CE28739 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 632
Score = 209 bits (532), Expect = 2e-53
Identities = 134/474 (28%), Positives = 228/474 (47%), Gaps = 57/474 (12%)
Query: 83 LNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGK 142
L N SL + T + T D + P L ++ + + + A ++
Sbjct: 4 LTPTNTSLDTTTTNNDTTSDREAAPTTLNLTPTASESENSLSPVTAEDLIAK-------S 56
Query: 143 ITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI 202
I + K+ NDF F +++G+G+YS V + ++ +AVK+L K YL + +K+ +
Sbjct: 57 IKEGCPKRTSNDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIR 116
Query: 203 EKNTLQRLKNTKG----IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQY 258
EKN L L G + LY F D++ +YF++ NGDL + GS + +++
Sbjct: 117 EKNILTYLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKF 176
Query: 259 YAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLL-------------- 304
+A++I+ L F+HD ++HRD+KP+N+L+ D + +TDFG+A+
Sbjct: 177 FASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDAN 236
Query: 305 --DSTSED-----------DLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
S S D D + + R +FVGTA YVSPE+L D V + DIW GC
Sbjct: 237 QASSRSSDSGSPPPTRFYSDEEEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGC 296
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQI 411
ILFQ +AG+PPF+A N+Y +++ ++ F+F GFP +++ IL+++P R+ ++
Sbjct: 297 ILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRITSQEL 356
Query: 412 KAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQSSVPKVASSPA----INPIHEPVRQ 467
AH+FF +V++ N + + PP L Y +P P I P+ +
Sbjct: 357 MAHKFFENVDWVN--IANIKPPVLHAY----------IPATFGEPEYYSNIGPVEPGLDD 404
Query: 468 SSVSPKITPKNTTTAQRPNGDTTSTTTKRELDPRTQRILNNVKKEISQRNHRRA 521
++ + N +A +P +T + + DP I E + RA
Sbjct: 405 RALFRLMNLGNDASASQP---STPSNVEHRGDPFVSEIAPRANSEAEKNRAARA 455
>CE28740 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 636
Score = 208 bits (530), Expect = 3e-53
Identities = 135/476 (28%), Positives = 229/476 (47%), Gaps = 57/476 (11%)
Query: 83 LNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGK 142
L N SL + T + T D + P L ++ + + + A ++
Sbjct: 4 LTPTNTSLDTTTTNNDTTSDREAAPTTLNLTPTASESENSLSPVTAEDLIAK-------S 56
Query: 143 ITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI 202
I + K+ NDF F +++G+G+YS V + ++ +AVK+L K YL + +K+ +
Sbjct: 57 IKEGCPKRTSNDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIR 116
Query: 203 EKNTLQRLKNTKG----IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQY 258
EKN L L G + LY F D++ +YF++ NGDL + GS + +++
Sbjct: 117 EKNILTYLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKF 176
Query: 259 YAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTA----------------- 301
+A++I+ L F+HD ++HRD+KP+N+L+ D + +TDFG+A
Sbjct: 177 FASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDAN 236
Query: 302 ----RLLDS--------TSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAF 349
R DS S++++ + R +FVGTA YVSPE+L D V + DIW
Sbjct: 237 QASSRSSDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGL 296
Query: 350 GCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLIN 409
GCILFQ +AG+PPF+A N+Y +++ ++ F+F GFP +++ IL+++P R+
Sbjct: 297 GCILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRITSQ 356
Query: 410 QIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQSSVPKVASSPA----INPIHEPV 465
++ AH+FF +V++ N + + PP L Y +P P I P+ +
Sbjct: 357 ELMAHKFFENVDWVN--IANIKPPVLHAY----------IPATFGEPEYYSNIGPVEPGL 404
Query: 466 RQSSVSPKITPKNTTTAQRPNGDTTSTTTKRELDPRTQRILNNVKKEISQRNHRRA 521
++ + N +A +P+ S R DP I E + RA
Sbjct: 405 DDRALFRLMNLGNDASASQPSTFRPSNVEHRG-DPFVSEIAPRANSEAEKNRAARA 459
>CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 320
Score = 192 bits (488), Expect = 2e-48
Identities = 108/288 (37%), Positives = 172/288 (59%), Gaps = 15/288 (5%)
Query: 150 KGINDFKFGETLGDGSYSTVLLATSIE----SNKKYAVKILNKEYLIKQKKVKYVNIEKN 205
K + D+ + +G+GS+STV LA E N + A+KI K ++K K V Y++ EK
Sbjct: 21 KCLADYSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKE 80
Query: 206 TLQRLKNTK----GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKH--GSVNEKCTQYY 259
L + + GI++LY TFQD SLYF+LEYA GDL +LM+K N ++YY
Sbjct: 81 ALALISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYY 140
Query: 260 AAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDS---TSEDDLKYDL 316
AA ++ AL +H G+IHRD+K +N+L+ D ++ LTDFG+++ L E+ ++ +
Sbjct: 141 AANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQ 200
Query: 317 LT-RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKV 375
T R +SFVGTA +V+PELL + + D+WAF L+ + G PF +EYL F+++
Sbjct: 201 PTGRRSSFVGTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRI 260
Query: 376 MKVQFAFTAGFP-MTVRDLVKNILIKNPERRLLINQIKAHQFFADVNF 422
+ + F+ FP ++L++ +L+K + RL +IK H+FF ++F
Sbjct: 261 QDILYTFSEDFPDENAKNLIERLLVKEQKSRLTSQEIKEHKFFESIDF 308
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 173 bits (439), Expect = 1e-42
Identities = 106/344 (30%), Positives = 182/344 (52%), Gaps = 29/344 (8%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
GI+DF+ + +G G++ V E+++ YA+K++ K++++++ +Y+ E++ L ++
Sbjct: 130 GIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKI 189
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
+ I+ L ++FQ + LY +L++ G L + G E + Y A+I+ A+ +
Sbjct: 190 DHPF-IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 248
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H+KG++HRDLKPENIL+D D V LTDFG A+ +++ TRSNS GT EY+
Sbjct: 249 HEKGIMHRDLKPENILMDTDGHVMLTDFGLAK----------EFEENTRSNSMCGTTEYM 298
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE++ D D W+ G +L++M+ GKPPF + + QK++K +
Sbjct: 299 APEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQ-QKIVKDKIKLPQFLSNEA 357
Query: 391 RDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDK-DPPELGPY---KVS 441
++K +L K PERRL +IK H++F +N W K + E+ P +VS
Sbjct: 358 HAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGIN------WKKLEAREVMPSFKPEVS 411
Query: 442 ARALQSSVPKVASSPAINPIHEPVRQSSVSPKITPKNTTTAQRP 485
R ++ K + ++ + P S PK P T RP
Sbjct: 412 GRQCIANFDKCWTDMSV--LDSPASSPSSDPKANPFTNFTYVRP 453
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 171 bits (433), Expect = 5e-42
Identities = 102/315 (32%), Positives = 170/315 (53%), Gaps = 18/315 (5%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF F + +G GS+ VLLA YAVK+L K+ ++K+K+ K++ E+N L LKN
Sbjct: 96 SDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVL--LKN 153
Query: 213 TKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
K ++ L+F+FQ LYF+L+Y G+L +++ E ++YAA+I ALG++
Sbjct: 154 VKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYL 213
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H +++RDLKPENILLD + LTDFG + ++++++ T ++F GT EY+
Sbjct: 214 HSLNIVYRDLKPENILLDSQGHIVLTDFGLCK-------ENIEHNSTT--STFCGTPEYL 264
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE+L+ D D W G +L++M+ G PPF + N + ++ +
Sbjct: 265 APEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSA 324
Query: 391 RDLVKNILIKNPERRLLIN----QIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQ 446
R L++ +L K+ +RL +IK+H FF+ +N+ + + K P P L+
Sbjct: 325 RHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINW-DDLINKKITPPFNPNVSGPNELR 383
Query: 447 SSVPKVASSPAINPI 461
P+ P N I
Sbjct: 384 HFDPEFTEEPVPNSI 398
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 171 bits (432), Expect = 6e-42
Identities = 90/282 (31%), Positives = 158/282 (55%), Gaps = 25/282 (8%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+NDF+ +G GSY+ V+ A + + + YA+KI+ KE + + + +V EK+ +
Sbjct: 250 LNDFRLLTVIGRGSYAKVVQAEHVSTRQIYAIKIIKKEMFNEDEDIDWVQTEKSVFEAAS 309
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N ++ L+ FQ ES L+F++E+ P GDL+ M++ + E+ ++Y+ +II AL F+H
Sbjct: 310 NYPFLVGLHSCFQTESRLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLH 369
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+G+I+RDLK +N+L+D + +KLTD+G + ++ + DL +++F GT Y++
Sbjct: 370 SRGIIYRDLKLDNVLIDAEGHIKLTDYGMCK--ENIKDGDL-------TSTFCGTPNYIA 420
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPF--------KANNEYLTFQKVMKVQFAFT 383
PE+L + F D WA G ++F+M+AG+ PF + N E FQ +++ Q
Sbjct: 421 PEILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIP 480
Query: 384 AGFPMTVRDLVKNILIKNPERRL--------LINQIKAHQFF 417
+ ++K L K+P RL + +K HQFF
Sbjct: 481 RSLSVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFF 522
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 171 bits (432), Expect = 6e-42
Identities = 107/332 (32%), Positives = 176/332 (52%), Gaps = 21/332 (6%)
Query: 120 QKEWADRGAAMIVKDVPDKQ-----TGKITKQVIKKGINDFKFGETLGDGSYSTVLLATS 174
Q + D A I +D +Q T + V K + +F+F + LG G++ V+L
Sbjct: 145 QTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCRE 204
Query: 175 IESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLE 234
+ K YA+KIL KE +I++ +V + E L+ N +ISL ++FQ L F+++
Sbjct: 205 KATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKST-NHPFLISLKYSFQTNDRLCFVMQ 263
Query: 235 YAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVK 294
Y G+L + E T++Y A+II ALG++H +G+I+RDLK EN+LLD D +K
Sbjct: 264 YVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIK 323
Query: 295 LTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILF 354
+ DFG + +D+ Y T+ +F GT EY++PE+L+DN D W G +++
Sbjct: 324 VADFGLCK-------EDITYGRTTK--TFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMY 374
Query: 355 QMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LIN 409
+MI G+ PF + + F ++ + F ++L+ +L K+P++RL +
Sbjct: 375 EMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVK 434
Query: 410 QIKAHQFFADVNFGNGSVWDKDPPELGPYKVS 441
+I+AH FFA +N+ V K PP P S
Sbjct: 435 EIQAHPFFASINW-TDLVLKKIPPPFKPQVTS 465
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 169 bits (428), Expect = 2e-41
Identities = 97/328 (29%), Positives = 183/328 (55%), Gaps = 34/328 (10%)
Query: 111 PISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKG---INDFKFGETLGDGSYS 167
P + QR+Q++ + ++ +P K ++ KG ++DF+ TLG GS+
Sbjct: 30 PHHDLQQRQQQQQQRQHQQLLTSQLPQKS-------LVSKGKYTLHDFQIMRTLGTGSFG 82
Query: 168 TVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDES 227
V L S+ + + YA+K+L K+ ++K K+V++ N E+ L+ +++ +I ++ TFQD
Sbjct: 83 RVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPF-LIRMWGTFQDAR 141
Query: 228 SLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILL 287
+++ +++Y G+L SL+RK ++YAA++I AL ++H +I+RDLKPENILL
Sbjct: 142 NIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILL 201
Query: 288 DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIW 347
D + +K+TDFG A+ ++ T + + GT +Y++PE++ + D W
Sbjct: 202 DRNGHIKITDFGFAK------------EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWW 249
Query: 348 AFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLL 407
+ G ++++M+AG PF T++K+++ + + F V DL+ ++ + RR+
Sbjct: 250 SLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIG 309
Query: 408 INQ-----IKAHQFFADVNFGNGSVWDK 430
Q IKAH +F++V VW++
Sbjct: 310 NLQSGSRDIKAHPWFSEV------VWER 331
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 169 bits (428), Expect = 2e-41
Identities = 96/282 (34%), Positives = 159/282 (56%), Gaps = 19/282 (6%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
NDF + T+G GS+ V E+ K YA+KIL+KE++ K+ +VK+V E+N L
Sbjct: 92 NDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFK 151
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
++SL+F+FQ++ LYF+L++ G+L S +++ +E +++YAA+I ALG++H+
Sbjct: 152 HPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHE 211
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
K +I+RDLKPEN+LLD + LTDFG + +D++ T ++F GT EY++P
Sbjct: 212 KNIIYRDLKPENLLLDDKGYLVLTDFGLCK-------EDMQGSKTT--STFCGTPEYLAP 262
Query: 333 ELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRD 392
E++ D D W G +L++MI G PPF + + + K++ + +
Sbjct: 263 EIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSE 322
Query: 393 LVKNILIKNPERRL----LINQIKAHQFFADVNFGNGSVWDK 430
L+ +L K+ +RL I+ H FF V+ WDK
Sbjct: 323 LITGLLQKDRSKRLGHRNDFRDIRDHPFFLPVD------WDK 358
>At1g30640 [R] KOG0605 NDR and related serine/threonine kinases
Length = 562
Score = 169 bits (428), Expect = 2e-41
Identities = 104/394 (26%), Positives = 202/394 (50%), Gaps = 66/394 (16%)
Query: 72 VDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGAAMI 131
++N + K L R + S +E + D ++++ ++ I ++ ++++ E+
Sbjct: 58 IENHYKIQKKSLQERKERRSILE--QNLADADVTVEDKMDILKNFEKKEMEYM------- 108
Query: 132 VKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYL 191
++ +Q K G++DF+ +G G++ V + + YA+K L K +
Sbjct: 109 ----------RLQRQ--KMGVDDFELLSIIGRGAFGEVRICKEKSTGSVYAMKKLKKSEM 156
Query: 192 IKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
+++ +V++V E+N L + ++ I+ L ++FQD+ LY ++EY P GD+++L+ + ++
Sbjct: 157 LRRGQVEHVKAERNVLAEV-DSPFIVKLCYSFQDDEHLYLIMEYLPGGDMMTLLMRKDTL 215
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
E T++Y AQ I A+ +H +HRD+KP+N+L+ + +KL+DFG ++ L+S + D
Sbjct: 216 REDETRFYVAQTILAIESIHKHNYVHRDIKPDNLLITRNGHIKLSDFGLSKSLESKNFPD 275
Query: 312 LKYDLLTRSN------------------------------------SFVGTAEYVSPELL 335
K +L+ RS S VGT +Y++PE+L
Sbjct: 276 FKAELVDRSTKPAAEHDRLSKPPSAPRRTQQEQLLHWQQNRRTLAFSTVGTPDYIAPEVL 335
Query: 336 NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK----VQFAFTAGFPMTVR 391
CD W+ G I+F+M+ G PPF + T +K++ ++F A + V+
Sbjct: 336 LKKGYGMECDWWSLGAIMFEMLVGFPPFYSEEPLATCRKIVNWKTCLKFPDEAKLSIEVK 395
Query: 392 DLVKNILIKNPERRL---LINQIKAHQFFADVNF 422
DL++ +L N E+RL +++IKAH +F V +
Sbjct: 396 DLIRRLLC-NVEQRLGTKGVHEIKAHPWFRGVEW 428
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 169 bits (427), Expect = 2e-41
Identities = 105/349 (30%), Positives = 179/349 (51%), Gaps = 21/349 (6%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
GI DF+ + +G G++ V ++++ YA+K++ K+ ++++ +Y+ E++ L ++
Sbjct: 136 GIEDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKI 195
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
+ I+ L ++FQ + LY +L++ G L + G E + Y A+I+ A+ +
Sbjct: 196 DHPF-IVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHL 254
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H+KG++HRDLKPENIL+DVD V LTDFG A+ +++ TRSNS GT EY+
Sbjct: 255 HEKGIMHRDLKPENILMDVDGHVMLTDFGLAK----------EFEENTRSNSMCGTTEYM 304
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE++ D D W+ G +L++M+ GKPPF + + QK++K +
Sbjct: 305 APEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQ-QKIVKDKIKLPQFLSNEA 363
Query: 391 RDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARAL 445
L+K +L K PERRL +IK H++F +N+ + P P VS R
Sbjct: 364 HALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLEAREVQ-PSFKP-AVSGRQC 421
Query: 446 QSSVPKVASSPAINPIHEPVRQSSVSPKITPKNTTTAQRPNGDTTSTTT 494
++ K + ++ + P + K P T RP TT
Sbjct: 422 IANFDKCWTDMSV--LDSPASSPNSDAKANPFTNFTYVRPPHSFLHRTT 468
>YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 824
Score = 168 bits (426), Expect = 3e-41
Identities = 117/357 (32%), Positives = 190/357 (52%), Gaps = 29/357 (8%)
Query: 134 DVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK 193
D+ K T K TK+ G DF+ LG G++ V ++ + YA+K+L+K+ ++K
Sbjct: 392 DILIKWTYKQTKKR-HYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVK 450
Query: 194 QKKVKYVNIEKNTLQRL--KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
+ ++ + E+N L K++ I+ L F+FQ + LY + +Y G+L ++K G
Sbjct: 451 KNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRF 510
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
+E ++Y A+++ AL +HD +++RDLKPENILLD + + L DFG +
Sbjct: 511 SEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLS---------- 560
Query: 312 LKYDLLTRSNSFVGTAEYVSPELLND--NYVDFRCDIWAFGCILFQMIAGKPPFKANNEY 369
K DL R+N+F GT EY++PELL D Y D W+ G ++F+M G PF A N
Sbjct: 561 -KADLKDRTNTFCGTTEYLAPELLLDETGYTKM-VDFWSLGVLIFEMCCGWSPFFAENNQ 618
Query: 370 LTFQKVM--KVQFAFTAGFPMTVRDLVKNILIKNPERRLLI----NQIKAHQFFADVNFG 423
+QK+ KV+F R VK +L +NP+ RL +++AH FFAD+++
Sbjct: 619 KMYQKIAFGKVKFPRDV-LSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDW- 676
Query: 424 NGSVWDKDPPELGPYKVSARALQSSVPK--VASSPAINPIHEPVRQSS-VSPKITPK 477
K PP P+ VS + P+ AS+ +N H+P+ ++ +SP + K
Sbjct: 677 EALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNK-HQPMMTATPLSPAMQAK 732
>7294566 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1252
Score = 168 bits (426), Expect = 3e-41
Identities = 102/304 (33%), Positives = 168/304 (54%), Gaps = 34/304 (11%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
++ +DF +G G + V L ++N YA+K + K ++ +VK E+ +
Sbjct: 106 LRVNADDFLIKTLIGQGYFGNVHLVVERQTNDIYAMKKIKKS-VVTTSQVK----EERDI 160
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDAL 267
++N++ +I+L + FQD +LY ++EY P GDLLSLM +HG +E ++Y A++ AL
Sbjct: 161 MSIRNSEWLINLQYAFQDNDNLYLVMEYMPGGDLLSLMSRHGPFDEDLARFYLAELTVAL 220
Query: 268 GFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTA 327
+H+ G +HRD+KPENIL+D +KL DFG A LD D S S VGT
Sbjct: 221 HTLHEMGYVHRDIKPENILIDRFGHIKLADFGNAAALDR--------DGHVLSLSPVGTP 272
Query: 328 EYVSPEL--------LNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKV---- 375
+Y++PEL L+ + D CD W+ G I +++I PF +N + T+ K+
Sbjct: 273 DYIAPELLQTISTYKLSKSMHDVSCDYWSMGIIGYELICETTPFHEDNVHETYSKILSHC 332
Query: 376 ----MKVQFAFTAGFPMTV--RDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWD 429
+K +F A ++V R+L+++ L+ NP +RL +IK H FF+++ + GS+
Sbjct: 333 EESHLKELISFPADLKVSVNYRNLIES-LVTNPSKRLSYERIKNHPFFSEIPW--GSIRS 389
Query: 430 KDPP 433
+ PP
Sbjct: 390 QVPP 393
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 168 bits (425), Expect = 4e-41
Identities = 90/276 (32%), Positives = 163/276 (58%), Gaps = 18/276 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++ F+ +TLG GS+ V+L E+ YA+KIL+K+ ++K K++++ EK LQ +
Sbjct: 41 LDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV- 99
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N ++ L F+F+D S+LY ++EY P G++ S +R+ G +E ++YAAQI+ ++H
Sbjct: 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+I+RDLKPEN+L+D +++TDFG A+ + R+ + GT EY++
Sbjct: 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG------------RTWTLCGTPEYLA 207
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ + D WA G ++++M AG PPF A+ ++K++ + F + F ++
Sbjct: 208 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLK 267
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
DL++N+L + +R +N IK H++FA ++
Sbjct: 268 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 303
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 168 bits (425), Expect = 4e-41
Identities = 110/343 (32%), Positives = 171/343 (49%), Gaps = 23/343 (6%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
K + DF F + LG GS+ V+LA +++ YA+K+L K+ +I+ V EK L
Sbjct: 402 KCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILA 461
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
N + +L+ FQ L+F++EY GDL+ ++K +YAA++ AL
Sbjct: 462 LAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQ 521
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
F+H GVI+RDLK +NILLD + KL DFG + + + +LT +F GT +
Sbjct: 522 FLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCK-------EGIMNGMLT--TTFCGTPD 572
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
Y++PE+L + D WA G ++++M+AG+PPF+A+NE F +M +
Sbjct: 573 YIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSR 632
Query: 389 TVRDLVKNILIKNPERRLLI----NQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARA 444
++K L KNPE+RL N+I+ H FFA +++ + PP K A
Sbjct: 633 EAVSILKGFLTKNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDA 692
Query: 445 LQSSVPKVASSPAINPI-HEPVR---------QSSVSPKITPK 477
P + PI +E VR S V+PK P+
Sbjct: 693 NNFDAEFTKEDPVLTPIGNEVVRCINQDEFAGFSFVNPKFGPE 735
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 167 bits (423), Expect = 7e-41
Identities = 89/277 (32%), Positives = 163/277 (58%), Gaps = 18/277 (6%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
G+ DF+ +TLG GS+ V+L + + YA+KIL+K+ ++K K++++ EK LQ +
Sbjct: 40 GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
N ++ L + F+D S+LY ++EY P G++ S +R+ G +E ++YAAQI+ ++
Sbjct: 100 -NFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H +I+RDLKPEN+L+D +++TDFG A+ + R+ + GT EY+
Sbjct: 159 HSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKG------------RTWTLCGTPEYL 206
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE++ + D WA G ++++M AG PPF A+ ++K++ + F + F +
Sbjct: 207 APEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDL 266
Query: 391 RDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+DL++N+L + +R ++ IK H++FA ++
Sbjct: 267 KDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 303
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 166 bits (421), Expect = 1e-40
Identities = 116/423 (27%), Positives = 207/423 (48%), Gaps = 28/423 (6%)
Query: 25 PTPPPIPMELSHPPLPTIRTTDDLSNLSEMKPFGKPNP---PVLTKALTDVDNFISLDPK 81
PTP P P+EL T DD +SE+ + PV +++ + + +
Sbjct: 697 PTPRPDPIELLLEGKGTFHDQDDFPQMSELADIARCAANAIPVDDQSIQLLLSCLEDLRV 756
Query: 82 YLNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTG 141
++RR VET TR + + K L + E M + D A + V +T
Sbjct: 757 VIDRRKFDALIVETF-GTRIEKLIQEKYLQLCELMDDEKGTIIDEDAPLEDDVVRSLRTS 815
Query: 142 KITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVN 201
+ + + I+DF+ +++ G++ V+LA + +A+K+L K +I++ V+ +
Sbjct: 816 PVHLRD-RISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESIL 874
Query: 202 IEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAA 261
E++ L +N ++ +++F +LY ++EY GD S++RK G ++E + Y A
Sbjct: 875 AERDILINARNPF-VVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCLDEANARVYIA 933
Query: 262 QIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDL--------- 312
+++ AL ++H +GV+HRDLKP+N+L+ D VKLTDFG +++ + DDL
Sbjct: 934 EVVLALEYLHSEGVVHRDLKPDNLLIAHDGHVKLTDFGLSKVGLINNTDDLSGPVSSATS 993
Query: 313 -------KYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKA 365
K L S VGT +Y++PE+L D W+ G IL++ + G PPF A
Sbjct: 994 LLVEEKPKLPTLDHKRSAVGTPDYLAPEILLGTGHGATADWWSVGIILYEFLVGIPPFNA 1053
Query: 366 NNEYLTFQKVMKVQFAF---TAGFPMTVRDLVKNILIKNPERRLLIN---QIKAHQFFAD 419
++ F ++ + RDL+ +L ++P +RL ++K H FF D
Sbjct: 1054 DHPQQIFDNILNRNIQWPPVPEDMSHEARDLIDRLLTEDPHQRLGARGAAEVKQHSFFKD 1113
Query: 420 VNF 422
+++
Sbjct: 1114 IDW 1116
>Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 358
Score = 166 bits (420), Expect = 2e-40
Identities = 92/276 (33%), Positives = 159/276 (57%), Gaps = 18/276 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DF T+G G++ V L + +A+K+++ +I+ K+ ++V+ EK+ L+ +
Sbjct: 46 LQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVS 105
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ +I L++T+ DE LY L+EY P G+L S +R G + +Y+A+II A+ ++H
Sbjct: 106 HPF-LIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLH 164
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K +++RDLKPENILLD D +KLTDFG A+ L+ R+ + GT EY++
Sbjct: 165 SKEIVYRDLKPENILLDRDGHIKLTDFGFAK------------KLVDRTWTLCGTPEYLA 212
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ D WA G ++F+M++G PPF +N + +QK++ + F V+
Sbjct: 213 PEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVK 272
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
DL+K +L+ + RRL N +K H++F V++
Sbjct: 273 DLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDW 308
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 165 bits (418), Expect = 3e-40
Identities = 99/295 (33%), Positives = 156/295 (52%), Gaps = 19/295 (6%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLI-KQKKVKYVNIE 203
IK G DF+ + LG G Y V ++NK +A+K+L K ++ QK + E
Sbjct: 70 IKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAE 129
Query: 204 KNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQI 263
+N L+ +K+ I+ L + FQ + LY +LEY G+L + + G E T +Y ++I
Sbjct: 130 RNILEAVKHPF-IVELVYAFQTDGKLYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEI 188
Query: 264 IDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSF 323
I ALG +H G+I+RDLKPENILLD VKLTDFG + + ++ ++T ++F
Sbjct: 189 ILALGHLHKLGIIYRDLKPENILLDAQGHVKLTDFGLCK-------EHIQEGIVT--HTF 239
Query: 324 VGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT 383
GT EY++PE+L + D W+ G ++F M+ G PPF A N T + ++K +
Sbjct: 240 CGTIEYMAPEILTRSGHGKAVDWWSLGALMFDMLTGVPPFTAENRKKTIETILKAKLNLP 299
Query: 384 AGFPMTVRDLVKNILIKNPERRLLIN-----QIKAHQFFADVNFGNGSVWDKDPP 433
A RDLV+ ++ + +RL ++ H FF VN+ + +PP
Sbjct: 300 AYLTPEARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFKHVNWDDVLARRLEPP 354
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 165 bits (417), Expect = 3e-40
Identities = 94/282 (33%), Positives = 163/282 (57%), Gaps = 24/282 (8%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
+F+ TLG GS+ V L S + + YA+K+L KE +++ K+V++ N E+ L + +
Sbjct: 86 NFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHP 145
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
II ++ TFQD ++ +++Y G+L SL+RK ++YAA++ AL ++H K
Sbjct: 146 F-IIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSK 204
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
+I+RDLKPENILLD + +K+TDFG A+ + D+ Y L GT +Y++PE
Sbjct: 205 DIIYRDLKPENILLDKNGHIKITDFGFAKYV-----PDVTYTL-------CGTPDYIAPE 252
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+++ + D W+FG ++++M+AG PF +N T++K++ + F F V+DL
Sbjct: 253 VVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDL 312
Query: 394 VKNILIKNPERRL--LIN---QIKAHQFFADVNFGNGSVWDK 430
+ ++ ++ +RL L N +K H +F +V VW+K
Sbjct: 313 LSRLITRDLSQRLGNLQNGTEDVKNHPWFKEV------VWEK 348
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 165 bits (417), Expect = 3e-40
Identities = 107/367 (29%), Positives = 179/367 (48%), Gaps = 27/367 (7%)
Query: 103 NISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLG 162
NIS +L +++R+ KE + G + V + GI++F+F LG
Sbjct: 314 NISPTSKLVSRSTLRRQGKESSKEGNGIGVNSSN------------RLGIDNFEFIRVLG 361
Query: 163 DGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFT 222
GS+ V+LA E+ YAVK+L K+ ++ V+ EK L +N + L+
Sbjct: 362 KGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKRILSLARNHPFLTQLFCC 421
Query: 223 FQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKP 282
FQ L+F++E+ GDL+ ++K +E ++YAA+II AL F+HDKG+I+RDLK
Sbjct: 422 FQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKL 481
Query: 283 ENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDF 342
+N+LLD + KL DFG + + + + T +F GT +Y++PE+L +
Sbjct: 482 DNVLLDHEGHCKLADFGMCK-------EGICNGVTTA--TFCGTPDYIAPEILQEMLYGP 532
Query: 343 RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNP 402
D WA G +L++M+ G PF+A NE F+ ++ + + ++K+ + KNP
Sbjct: 533 AVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNP 592
Query: 403 ERRLLI------NQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQSSVPKVASSP 456
RL + I H FF ++++ + +PP K + P
Sbjct: 593 TMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFDPDFIKEEP 652
Query: 457 AINPIHE 463
+ PI E
Sbjct: 653 VLTPIDE 659
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 165 bits (417), Expect = 3e-40
Identities = 99/331 (29%), Positives = 174/331 (51%), Gaps = 27/331 (8%)
Query: 108 KELPISESMQRRQKEWADRGAAMIVKDVPDKQ------TGKITKQVIKK-GINDFKFGET 160
+E+ E+ R+ + +RG PD Q G++ + K+ G+++F F +
Sbjct: 354 QEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRLGLDEFNFIKV 413
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG GS+ V+LA ++ YAVK+L K+ +++ V EK L + + LY
Sbjct: 414 LGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLY 473
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
FQ + L+F++EY GDL+ +++ +E +++YAA++ AL F+H GVI+RDL
Sbjct: 474 CCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDL 533
Query: 281 KPENILLDVDMKVKLTDFGTAR--LLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDN 338
K +NILLD + KL DFG + +L+ + + +F GT +Y++PE+L +
Sbjct: 534 KLDNILLDAEGHCKLADFGMCKEGILNGVT-----------TTTFCGTPDYIAPEILQEL 582
Query: 339 YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNIL 398
D WA G ++++M+AG+PPF+A+NE F+ ++ + ++K +
Sbjct: 583 EYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFM 642
Query: 399 IKNPERRLLI-------NQIKAHQFFADVNF 422
KNP +RL + IK H FF ++++
Sbjct: 643 TKNPHKRLGCVASQNGEDAIKQHPFFKEIDW 673
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 165 bits (417), Expect = 3e-40
Identities = 97/328 (29%), Positives = 175/328 (52%), Gaps = 25/328 (7%)
Query: 112 ISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLL 171
+++ +QR+++E + + ++ +++ T +K +NDF + + LG G++ V+L
Sbjct: 105 VADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVIL 164
Query: 172 ATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKG--IISLYFTFQDESSL 229
S K YA+KIL KE +I + +V + E L KNT+ + SL ++FQ + L
Sbjct: 165 VREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVL---KNTRHPFLTSLKYSFQTKDRL 221
Query: 230 YFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDV 289
F++EY G+L + + +E T++Y A+I+ AL ++H +++RDLK EN++LD
Sbjct: 222 CFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDK 281
Query: 290 DMKVKLTDFGTAR--LLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIW 347
D +K+TDFG + + D+ + +F GT EY++PE+L DN D W
Sbjct: 282 DGHIKITDFGLCKEGITDAAT-----------MKTFCGTPEYLAPEVLEDNDYGRAVDWW 330
Query: 348 AFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL- 406
G ++++M+ G+ PF + F+ ++ F + L+ +LIK+P +RL
Sbjct: 331 GLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLG 390
Query: 407 ----LINQIKAHQFFADVNFGNGSVWDK 430
+I H FF+ VN+ + V+DK
Sbjct: 391 GGPDDAKEIMRHSFFSGVNWQD--VYDK 416
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 165 bits (417), Expect = 3e-40
Identities = 96/308 (31%), Positives = 177/308 (57%), Gaps = 22/308 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF +TLG GS+ V+L +S YA+KIL+K+ ++K K+V++ EK LQ +
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAI- 107
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ ++++ F+F+D S+LY +LE+ G++ S +R+ G +E +++YAAQI+ A ++H
Sbjct: 108 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 167
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+I+RDLKPEN+L+D +K+TDFG A+ + R+ + GT EY++
Sbjct: 168 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG------------RTWTLCGTPEYLA 215
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ + D WA G ++++M AG PPF A+ ++K++ + F + F ++
Sbjct: 216 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELK 275
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDK--DPPELGPYKVSARA 444
DL+KN+L + +R + IK H++F ++ +++ K PP + + R
Sbjct: 276 DLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDW--IAIYQKKITPPSFSKGESNGRL 333
Query: 445 LQSSVPKV 452
++ P+V
Sbjct: 334 FEALYPRV 341
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 164 bits (416), Expect = 4e-40
Identities = 94/287 (32%), Positives = 162/287 (55%), Gaps = 24/287 (8%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
K ++DF+ TLG GS+ V L S + + YA+K L K ++K K+V++ N E+ L
Sbjct: 82 KYSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLS 141
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
+ + II ++ TFQD ++ +++Y G+L SL+RK ++YAA++ AL
Sbjct: 142 IVSHPF-IIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALE 200
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
++H K +I+RDLKPENILLD + +K+TDFG A+ + D+ Y L GT +
Sbjct: 201 YLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-----PDVTYTL-------CGTPD 248
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
Y++PE+++ + D W+FG ++++M+AG PF +N T++ ++ + F F
Sbjct: 249 YIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHP 308
Query: 389 TVRDLVKNILIKNPERRL--LIN---QIKAHQFFADVNFGNGSVWDK 430
+DL+K ++ ++ RL L N +K H +F +V +W+K
Sbjct: 309 DAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEV------IWEK 349
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 164 bits (416), Expect = 4e-40
Identities = 91/300 (30%), Positives = 166/300 (55%), Gaps = 27/300 (9%)
Query: 138 KQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKV 197
+++GK + + G+ DF +G GSY+ VLL ++++ YA+K++ KE + + +
Sbjct: 231 RESGKASSSL---GLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDI 287
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+V EK+ ++ N ++ L+ FQ ES L+F++EY GDL+ M++ + E+ +
Sbjct: 288 DWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHAR 347
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLL 317
+Y+A+I AL ++H++G+I+RDLK +N+LLD + +KLTD+G + + D
Sbjct: 348 FYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK--EGLRPGD------ 399
Query: 318 TRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPF---------KANNE 368
+++F GT Y++PE+L F D WA G ++F+M+AG+ PF N E
Sbjct: 400 -TTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTE 458
Query: 369 YLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLIN------QIKAHQFFADVNF 422
FQ +++ Q + ++K+ L K+P+ RL + I+ H FF +V++
Sbjct: 459 DYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDW 518
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 164 bits (415), Expect = 6e-40
Identities = 89/285 (31%), Positives = 155/285 (54%), Gaps = 14/285 (4%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF F + +G GS+ VLLA +++ YAVK+L K+ +I+ ++ EK L
Sbjct: 370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRP 429
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
++S++ FQ L+F++EY GDL+ M+++G E +YA ++ AL F+H++
Sbjct: 430 PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
+I+RDLK +NILLD + VKL DFG ++ + +E + +F GT Y++PE
Sbjct: 490 DIIYRDLKLDNILLDGEGHVKLVDFGLSK--EGVTERQ-------TTRTFCGTPNYMAPE 540
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+++ + D W+FG +LF+ +AG+ PF+ ++E F+ + + F F + D+
Sbjct: 541 IVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDI 600
Query: 394 VKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPP 433
+ + L K P RL +I H FF +V++ + +PP
Sbjct: 601 ITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPP 645
>7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 353
Score = 164 bits (415), Expect = 6e-40
Identities = 92/276 (33%), Positives = 164/276 (59%), Gaps = 18/276 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF+ +TLG GS+ V++ + YA+KIL+K+ ++K K+V++ EK LQ ++
Sbjct: 43 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQ 102
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
++SL + F+D S+LY +LEY P G++ S +RK G +E +++YAAQI+ A ++H
Sbjct: 103 -FPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLH 161
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+I+RDLKPEN+L+D +K+TDFG A+ + R+ + GT EY++
Sbjct: 162 YLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKG------------RTWTLCGTPEYLA 209
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ + D WA G ++++M AG PPF A+ ++K++ + F + F ++
Sbjct: 210 PEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLK 269
Query: 392 DLVKNILIKNPERR-----LLINQIKAHQFFADVNF 422
DL++N+L + +R +N IK ++FA ++
Sbjct: 270 DLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDW 305
>At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1263
Score = 164 bits (414), Expect = 8e-40
Identities = 125/456 (27%), Positives = 213/456 (46%), Gaps = 59/456 (12%)
Query: 14 TSGSARSVMHR---PTPPPIPMELSHPPLPTIRTTDDLSNLSEMKPFGK----------P 60
T+ SA S+ R PTP P P+E T DD+ +SE+ K
Sbjct: 741 TTSSASSMTPRSPIPTPRPDPIEQILGGKGTFHDQDDIPQMSELADIAKCAADAIPGDDQ 800
Query: 61 NPPVLTKALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQ 120
+ P L L D+ I +RR +VET TR + + K + + E M
Sbjct: 801 SIPFLLSCLEDLRVVI-------DRRKFDALTVETF-GTRIEKLIREKYVHMCELMD--- 849
Query: 121 KEWADRGAAMIVKDVP--DKQTGKITKQVI----KKGINDFKFGETLGDGSYSTVLLATS 174
E D + +I +D P D + + + I+DF+ + + G++ V LA
Sbjct: 850 DEKVDLLSTVIDEDAPLEDDVVRSLRTSPVHPRDRTSIDDFEIIKPISRGAFGRVFLAKK 909
Query: 175 IESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLE 234
+ +A+K+L K +I++ V+ + E++ L ++N ++ +++F +LY ++E
Sbjct: 910 RTTGDLFAIKVLKKADMIRKNAVESILAERDILINVRNPF-VVRFFYSFTCRDNLYLVME 968
Query: 235 YAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVK 294
Y GDL SL+R G + E + Y A+++ AL ++H +GV+HRDLKP+N+L+ D +K
Sbjct: 969 YLNGGDLYSLLRNLGCLEEDIVRVYIAEVVLALEYLHSEGVVHRDLKPDNLLIAHDGHIK 1028
Query: 295 LTDFGTARLLDSTSEDDLKYDLLT----------------------RSNSFVGTAEYVSP 332
LTDFG +++ S DDL ++ + S VGT +Y++P
Sbjct: 1029 LTDFGLSKVGLINSTDDLAGPAVSGTSLLDEEESRLAASEEQLERRKKRSAVGTPDYLAP 1088
Query: 333 ELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF---TAGFPMT 389
E+L D W+ G ILF++I G PPF A + F ++ + +
Sbjct: 1089 EILLGTGHGATADWWSVGIILFELIVGIPPFNAEHPQQIFDNILNRKIPWPHVPEEMSAE 1148
Query: 390 VRDLVKNILIKNPERRLLIN---QIKAHQFFADVNF 422
D++ L ++P +RL ++K H FF D+N+
Sbjct: 1149 AHDIIDRFLTEDPHQRLGARGAAEVKQHIFFKDINW 1184
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 164 bits (414), Expect = 8e-40
Identities = 85/286 (29%), Positives = 162/286 (55%), Gaps = 11/286 (3%)
Query: 133 KDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLI 192
+ P + T + + + ++ G TLG+G+++ V A ++E+ A+K+++KE ++
Sbjct: 9 RSTPSRSTPSGSSSGGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVL 68
Query: 193 KQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVN 252
K K + + E +T++ +K+ +I ++ ++ +YF+LE+ G+L + +G +
Sbjct: 69 KNKMIAQIKREISTMKLIKHPN-VIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLK 127
Query: 253 EKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDL 312
E + Y Q+I+A+ + H +GV HRDLKPEN+LLD + +K++DFG + L ED L
Sbjct: 128 EDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSAL--PQQEDGL 185
Query: 313 KYDLLTRSNSFVGTAEYVSPELLND-NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLT 371
+ + GT YV+PE++N+ Y + D+W+ G ILF ++AG PF+ +N
Sbjct: 186 LH-------TTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSL 238
Query: 372 FQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
++K+ K +F F + + L+K IL NP R+ ++ +++F
Sbjct: 239 YKKIFKAEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWF 284
>7301980 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1105
Score = 162 bits (411), Expect = 2e-39
Identities = 99/305 (32%), Positives = 165/305 (53%), Gaps = 43/305 (14%)
Query: 161 LGDGSYSTVLLATSIE-SNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISL 219
+G G++ V L + I+ SN YA+K L K ++K+ +V +V E++ L N ++ L
Sbjct: 725 IGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNN-WVVKL 783
Query: 220 YFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRD 279
Y++FQD+ +LYF+++Y P GDL+SL+ K G E+ ++Y A++ A+ +H G IHRD
Sbjct: 784 YYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRD 843
Query: 280 LKPENILLDVDMKVKLTDFG------------------------TARLLDSTSEDDLKYD 315
+KP+NIL+D D +KLTDFG + + SE+ K
Sbjct: 844 IKPDNILIDRDGHIKLTDFGLCTGFRWTHNSKYYQENGNHSRQDSMEPWEEYSENGPKPT 903
Query: 316 LLTR----------SNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKA 365
+L R ++S VGT Y++PE+L + CD W+ G IL++M+ G+PPF A
Sbjct: 904 VLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLA 963
Query: 366 NNEYLTFQKVMK----VQFAFTAGFPMTVRDLVKNILIKNPERRL--LINQIKAHQFFAD 419
N+ T QKV+ + A DL++ L + ++RL ++++K+H FF
Sbjct: 964 NSPLETQQKVINWEKTLHIPPQAELSREATDLIRR-LCASADKRLGKSVDEVKSHDFFKG 1022
Query: 420 VNFGN 424
++F +
Sbjct: 1023 IDFAD 1027
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 162 bits (410), Expect = 2e-39
Identities = 90/276 (32%), Positives = 163/276 (58%), Gaps = 18/276 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF +TLG GS+ V+L +S YA+KIL+K+ ++K K+V++ EK LQ +
Sbjct: 49 LDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAI- 107
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ ++++ F+F+D S+LY +LE+ G++ S +R+ G +E +++YAAQI+ A ++H
Sbjct: 108 DFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLH 167
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+I+RDLKPEN+L+D +K+TDFG A+ + R+ + GT EY++
Sbjct: 168 SLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKG------------RTWTLCGTPEYLA 215
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ + D WA G ++++M AG PPF A+ ++K++ + F + F ++
Sbjct: 216 PEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELK 275
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
DL+KN+L + +R + IK H++F ++
Sbjct: 276 DLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDW 311
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 161 bits (408), Expect = 4e-39
Identities = 88/285 (30%), Positives = 155/285 (53%), Gaps = 22/285 (7%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
G+ DF +G GSY+ VLL ++++ YA+K++ KE + + + +V EK+ ++
Sbjct: 248 GLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQA 307
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
+ ++ L+ FQ S L+ ++EY GDL+ M++ + E+ ++YAA+I AL F+
Sbjct: 308 SSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFL 367
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H++G+I+RDLK +N+LLD D +KLTD+G + + D +++F GT Y+
Sbjct: 368 HERGIIYRDLKLDNVLLDADGHIKLTDYGMCK--EGLGPGD-------TTSTFCGTPNYI 418
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPF-------KANNEYLTFQKVMKVQFAFT 383
+PE+L F D WA G ++F+M+AG+ PF N E FQ +++
Sbjct: 419 APEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIP 478
Query: 384 AGFPMTVRDLVKNILIKNPERRL------LINQIKAHQFFADVNF 422
+ ++K L K+P+ RL + IK+H FF +++
Sbjct: 479 RFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDW 523
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 161 bits (408), Expect = 4e-39
Identities = 88/285 (30%), Positives = 155/285 (53%), Gaps = 22/285 (7%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
G+ DF +G GSY+ VLL ++++ YA+K++ KE + + + +V EK+ ++
Sbjct: 248 GLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQA 307
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
+ ++ L+ FQ S L+ ++EY GDL+ M++ + E+ ++YAA+I AL F+
Sbjct: 308 SSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFL 367
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H++G+I+RDLK +N+LLD D +KLTD+G + + D +++F GT Y+
Sbjct: 368 HERGIIYRDLKLDNVLLDADGHIKLTDYGMCK--EGLGPGD-------TTSTFCGTPNYI 418
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPF-------KANNEYLTFQKVMKVQFAFT 383
+PE+L F D WA G ++F+M+AG+ PF N E FQ +++
Sbjct: 419 APEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIP 478
Query: 384 AGFPMTVRDLVKNILIKNPERRL------LINQIKAHQFFADVNF 422
+ ++K L K+P+ RL + IK+H FF +++
Sbjct: 479 RFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDW 523
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 161 bits (408), Expect = 4e-39
Identities = 88/278 (31%), Positives = 160/278 (56%), Gaps = 16/278 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I+DF F + LG GS+ V+LA +++ YA+KIL K+ +++ V+ EK L
Sbjct: 375 IHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAA 434
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ +L+ +FQ L+F++EY GDL+ +++ +E ++YAA++ AL F+H
Sbjct: 435 KHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLH 494
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
VI+RDLK +NILLD + +L DFG + + ++D+L +++F GT +Y++
Sbjct: 495 RNDVIYRDLKLDNILLDAEGHCRLADFGMCK--EGINKDNL-------TSTFCGTPDYIA 545
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE+L + D WA G ++++M+AG+PPF+A+NE F+ ++ +
Sbjct: 546 PEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAV 605
Query: 392 DLVKNILIKNPERRL--LINQ-----IKAHQFFADVNF 422
+++K + KN +RL +++Q I+AH FF ++++
Sbjct: 606 NILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDW 643
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 161 bits (407), Expect = 5e-39
Identities = 87/273 (31%), Positives = 150/273 (54%), Gaps = 13/273 (4%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF F + +G G+Y VLLA YAVK+L K+ ++K+K+ ++ E++ L +
Sbjct: 94 DFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRH 153
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
++ L ++FQ LYF+L+Y G+L +++ E ++YAA++ A+G++H
Sbjct: 154 PFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
+I+RDLKPENILLD V LTDFG + + +D +++F GT EY++PE
Sbjct: 214 NIIYRDLKPENILLDCQGHVVLTDFGLCK--EGVEPED-------TTSTFCGTPEYLAPE 264
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+L D D W G +L++M+ G PPF + + ++ ++ G + DL
Sbjct: 265 VLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDL 324
Query: 394 VKNILIKNPERRLLIN----QIKAHQFFADVNF 422
++++L K+ +RL +IK H FF+ +N+
Sbjct: 325 LQSLLHKDQRQRLGSKADFLEIKNHVFFSPINW 357
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 160 bits (406), Expect = 6e-39
Identities = 95/301 (31%), Positives = 155/301 (50%), Gaps = 19/301 (6%)
Query: 141 GKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYV 200
G VIK +DF F LG GS+ VLL + + +A+K+L K+ +I+ V+
Sbjct: 401 GSSNHNVIKA--SDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKVLKKDVIIQDDDVECT 458
Query: 201 NIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYA 260
EK L + +++L+ FQ LYF++E+ GDL+ +++ G E +YA
Sbjct: 459 MTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYA 518
Query: 261 AQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRS 320
A+I L F+H KG+I+RDLK +N++L+ D +K+TDFG + +++ D T+
Sbjct: 519 AEIAVGLFFLHSKGIIYRDLKLDNVMLERDGHIKITDFGMCK-------ENIFGDATTK- 570
Query: 321 NSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQF 380
+F GT +Y++PE++ D WA+G +LF+M+AG+PPF +E F + +
Sbjct: 571 -TFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNV 629
Query: 381 AFTAGFPMTVRDLVKNILIKNPERRL--------LINQIKAHQFFADVNFGNGSVWDKDP 432
++ L K +LIKNP +RL IK H FF +++ P
Sbjct: 630 SYPKSLSKEAVSLCKALLIKNPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQP 689
Query: 433 P 433
P
Sbjct: 690 P 690
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 160 bits (404), Expect = 1e-38
Identities = 100/339 (29%), Positives = 172/339 (50%), Gaps = 20/339 (5%)
Query: 103 NISIPKELPISESMQRRQK-EWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETL 161
N+ IP E +M+ RQK E A G A P + + + + + + DF F L
Sbjct: 287 NVPIP-EGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVL 345
Query: 162 GDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYF 221
G GS+ V+LA + + YA+KIL K+ +I+ V+ +EK L L + L+
Sbjct: 346 GKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHS 405
Query: 222 TFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLK 281
FQ LYF++EY GDL+ +++ G E +YAA+I L F+H +G+I+RDLK
Sbjct: 406 CFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLK 465
Query: 282 PENILLDVDMKVKLTDFGTAR--LLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNY 339
+N++LD + +K+ DFG + ++D + + +F GT +Y++PE++
Sbjct: 466 LDNVMLDSEGHIKIADFGMCKEHMMDGVT-----------TRTFCGTPDYIAPEIIAYQP 514
Query: 340 VDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILI 399
D WA+G +L++M+AG+PPF +E FQ +M+ ++ + K ++
Sbjct: 515 YGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMT 574
Query: 400 KNPERRLLI-----NQIKAHQFFADVNFGNGSVWDKDPP 433
K+P +RL ++ H FF +++ + PP
Sbjct: 575 KHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPP 613
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 159 bits (403), Expect = 1e-38
Identities = 90/285 (31%), Positives = 148/285 (51%), Gaps = 14/285 (4%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF F + LG GS+ VLLA S + YA+KIL K+ +I+ V+ IEK L +
Sbjct: 349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKP 408
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
++ L+ FQ L+F++EY GDL+ +++ G E +YAA+I L F+H K
Sbjct: 409 PFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTK 468
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
G+++RDLK +N+LLD D VK+ DFG + +++ D T+ +F GT +Y++PE
Sbjct: 469 GILYRDLKLDNVLLDADGHVKIADFGMCK-------ENIVGDKTTK--TFCGTPDYIAPE 519
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
++ D WA+G +L++M+ G+PPF +E F + ++ ++
Sbjct: 520 IILYQPYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEA 579
Query: 394 VKNILIKNPERRLLI-----NQIKAHQFFADVNFGNGSVWDKDPP 433
K L K P +RL ++ H FF +++ + PP
Sbjct: 580 CKGFLTKQPNKRLGCGSSGEEDVRLHPFFRRIDWEKIENREVQPP 624
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 159 bits (402), Expect = 2e-38
Identities = 92/287 (32%), Positives = 159/287 (55%), Gaps = 13/287 (4%)
Query: 132 VKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYL 191
VK + KQ + +I + ++ G LG G+++ V LA + +S + A+K+++KE +
Sbjct: 8 VKSIKKKQDQSNHQALI---LGKYEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKV 64
Query: 192 IKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
+K + ++ E + L+R+++ I+ L+ +S +YF++EY G+L + + K G +
Sbjct: 65 LKSGLIAHIKREISILRRVRHPN-IVQLFEVMATKSKIYFVMEYVKGGELFNKVAK-GRL 122
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
E+ + Y Q+I A+ F H +GV HRDLKPEN+LLD + +K++DFG + + D +D
Sbjct: 123 KEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDG 182
Query: 312 LKYDLLTRSNSFVGTAEYVSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYL 370
L ++F GT YV+PE+L Y + DIW+ G ILF ++AG PF N
Sbjct: 183 L-------FHTFCGTPAYVAPEVLARKGYDGAKVDIWSCGVILFVLMAGFLPFHDRNVMA 235
Query: 371 TFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
++K+ + F FP+ + L+ +L PERR + I +F
Sbjct: 236 MYKKIYRGDFRCPRWFPVEINRLLIRMLETKPERRFTMPDIMETSWF 282
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 159 bits (401), Expect = 2e-38
Identities = 88/287 (30%), Positives = 154/287 (52%), Gaps = 10/287 (3%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
IK I DF + LG GS+ V LA ++N+ +A+K L K+ ++ V+ +EK L
Sbjct: 373 IKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVL 432
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDAL 267
+ ++ TFQ + +L+F++EY GDL+ ++ + +YAA+II L
Sbjct: 433 SLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGL 492
Query: 268 GFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTA 327
F+H KG+++RDLK +NILLD D +K+ DFG + +++ D ++N+F GT
Sbjct: 493 QFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCK-------ENMLGD--AKTNTFCGTP 543
Query: 328 EYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
+Y++PE+L + D W+FG +L++M+ G+ PF +E F + +
Sbjct: 544 DYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLE 603
Query: 388 MTVRDLVKNILIKNPERRLLI-NQIKAHQFFADVNFGNGSVWDKDPP 433
+DL+ + ++ PE+RL + I+ H F ++N+ + DPP
Sbjct: 604 KEAKDLLVKLFVREPEKRLGVRGDIRQHPLFREINWEELERKEIDPP 650
>At4g33080 [R] KOG0605 NDR and related serine/threonine kinases
Length = 483
Score = 159 bits (401), Expect = 2e-38
Identities = 102/348 (29%), Positives = 177/348 (50%), Gaps = 56/348 (16%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
++KD+ K+T + + K ++DF+ +G G++ V L +S YA+K L K
Sbjct: 70 MIKDLERKETEFMRLKRNKISVDDFELLTIIGRGAFGEVRLCRERKSGNIYAMKKLKKSE 129
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS 250
++ + +V++V E+N L +++ I+ LY++FQD LY ++EY P GD+++L+ + +
Sbjct: 130 MVMRGQVEHVRAERNLLAEVESHY-IVKLYYSFQDPEYLYLIMEYLPGGDMMTLLMREDT 188
Query: 251 VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLD----- 305
+ E ++Y AQ + A+ +H IHRD+KP+N+LLD D +KL+DFG + LD
Sbjct: 189 LREDVARFYIAQSVLAIESIHRYNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCRNLP 248
Query: 306 --------------------------------STSEDDLKYDLLTRSN---SFVGTAEYV 330
+ ++ L++ + R S VGT +Y+
Sbjct: 249 SIQENRATDDETMSEPMDVDRCFPDTDNKRSWRSPQEQLQHWQMNRRKLAFSTVGTPDYI 308
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQFAFTAGF 386
+PE+L CD W+ G I+++M+ G PPF A++ T +K++ ++F A F
Sbjct: 309 APEVLLKKGYGMECDWWSLGAIMYEMLVGYPPFYADDPISTCRKIVHWRNHLKFPEDAKF 368
Query: 387 PMTVRDLVKNILIKNPERRL----LINQIKAHQFFADVNFGNGSVWDK 430
+DL+ +L N + RL QIK H +F DV VW+K
Sbjct: 369 SSEAKDLICRLLC-NVDHRLGTGGGAQQIKDHPWFKDV------VWEK 409
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 159 bits (401), Expect = 2e-38
Identities = 93/290 (32%), Positives = 157/290 (54%), Gaps = 18/290 (6%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF F + +G GS+ VLLA K YAVK+L K+ ++ +K+ K++ E+N L LKN
Sbjct: 43 DFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVL--LKNV 100
Query: 214 KG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
K ++ L+++FQ LYF+L++ G+L +++ S E ++YAA+I ALG++H
Sbjct: 101 KHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLH 160
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+++RDLKPENIL+D V LTDFG + + S+ + +F GT EY++
Sbjct: 161 SIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIAISD---------TTTTFCGTPEYLA 211
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ D D W G +L++M+ G PPF + + ++ + G +
Sbjct: 212 PEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLRAW 271
Query: 392 DLVKNILIKNPERRLLIN----QIKAHQFFADVNFGNGSVWDKDPPELGP 437
+++ +L K+ + RL +I+ H FF +++ + V K PP P
Sbjct: 272 SILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWAD-LVQKKIPPPFNP 320
>CE08098 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1173
Score = 158 bits (400), Expect = 3e-38
Identities = 91/296 (30%), Positives = 162/296 (53%), Gaps = 20/296 (6%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF+ + +G G++ V L +N YA+K+LNK+ +IK+ + E++ + N+
Sbjct: 67 DFRQLKVIGRGAFGEVHLVRHTRTNTVYAMKMLNKDDMIKRADSAFFWEERDIMAHA-NS 125
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
+ I+ L + FQD LY ++EY P GDL++LM + V+EK T++Y A+I++AL +H
Sbjct: 126 EWIVRLQYAFQDPRHLYMVMEYMPGGDLVNLMTSY-EVSEKWTRFYTAEIVEALAALHSM 184
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
G IHRD+KP+N+L+ + +KL DFGT +++ + R ++ VGT +Y+SPE
Sbjct: 185 GYIHRDVKPDNMLISISGHIKLADFGTCVKMNANG--------VVRCSTAVGTPDYISPE 236
Query: 334 LLNDNYVDF----RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQFAFTAG 385
+L + D D W+ G +++M+ G+ PF A T+ +M ++F
Sbjct: 237 VLRNQGQDAEFGKEVDWWSVGVFIYEMLVGETPFYAEALVSTYTNIMNHKTSLKFPDEPL 296
Query: 386 FPMTVRDLVKNILIKNPER--RLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYK 439
+D++K L P+R R ++ I+ H+FF + + ++ + PP + K
Sbjct: 297 ISTQAKDIIKKFLSAAPDRLGRNSVDDIRNHKFFVNDEWTFATLREASPPVIPSLK 352
>7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 356
Score = 158 bits (399), Expect = 4e-38
Identities = 97/281 (34%), Positives = 156/281 (54%), Gaps = 24/281 (8%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
G++D++ TLG GS+ V L ES YA K L+K+ ++K K+V +V EKN L+ +
Sbjct: 43 GLDDYEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSM 102
Query: 211 K--NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
NT +I+ Y +D SLY +L G+L + RK EK ++YAAQ+ AL
Sbjct: 103 TFPNTVNLIASY---KDFDSLYLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALE 159
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
++H +++RDLKPENI++D + +K+TDFG A+ ++ TR+ + GT E
Sbjct: 160 YLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVE------------TRTMTLCGTPE 207
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYL--TFQKVMKVQFAFTAGF 386
Y+ PE++ D WAFG ++F+ +AG PF A+N + + K+ + + + F
Sbjct: 208 YLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYF 267
Query: 387 PMTVRDLVKNILIKNPERRL--LIN---QIKAHQFFADVNF 422
+R LV ++L + +R LIN IK H++F DV +
Sbjct: 268 SGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEW 308
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 157 bits (398), Expect = 5e-38
Identities = 85/264 (32%), Positives = 154/264 (58%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G+ LG G+++ V LA ++++N+ A+K+++KE ++K + ++ E + L+R+++
Sbjct: 26 YEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPN 85
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ ++ +YF++EY G+L + + K G + E+ + Y Q+I A+ F H +G
Sbjct: 86 -IVQLFEVMATKAKIYFVMEYVRGGELFNKVAK-GRLKEEVARKYFQQLISAVTFCHARG 143
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+LLD + +K++DFG + + D +D L ++F GT YV+PE+
Sbjct: 144 VYHRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGL-------FHTFCGTPAYVAPEV 196
Query: 335 L-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
L Y + DIW+ G ILF ++AG PF N ++K+ + +F F + L
Sbjct: 197 LARKGYDAAKVDIWSCGVILFVLMAGYLPFHDRNVMAMYKKIYRGEFRCPRWFSTELTRL 256
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+ +L NPE+R +I + +F
Sbjct: 257 LSKLLETNPEKRFTFPEIMENSWF 280
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 157 bits (397), Expect = 7e-38
Identities = 93/324 (28%), Positives = 157/324 (47%), Gaps = 22/324 (6%)
Query: 100 RDDNISIPKELPISESMQR---RQKEWADRGAAMIVKDVPDKQTGKITKQVIKK------ 150
R+ N IP P+ E + R K++ D ++ I + + K+ + K
Sbjct: 42 RNPNSKIPS--PVREKLNRLPVNNKKFLDMESSKIPSPIRKATSSKMIHENKKLPKFKSL 99
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
++DF+ G+ LG G + V + A+K++ KE +IK K E +Q
Sbjct: 100 SLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVE-IQTS 158
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
N + Y F DE +Y L+EY NG++ L+R HG N+ Y QI +AL +M
Sbjct: 159 LNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYM 218
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H K +IHRD+KPENIL+ + +KLTDFG + + + R + GT +Y+
Sbjct: 219 HKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPEN----------RRKTVCGTIDYL 268
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
SPE++ D D WA G + F+++ G PPF+ + T++++ + +
Sbjct: 269 SPEMVESREYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDA 328
Query: 391 RDLVKNILIKNPERRLLINQIKAH 414
+DL+ +L +P+ R+ + +K H
Sbjct: 329 QDLILKLLKYDPKDRMRLGDVKMH 352
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 157 bits (397), Expect = 7e-38
Identities = 93/299 (31%), Positives = 159/299 (53%), Gaps = 38/299 (12%)
Query: 140 TGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNK-EYLIKQ---- 194
+ I + + + ++DFK LG G+Y VLL + ++K YA+K L K E LI Q
Sbjct: 113 SSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATD 172
Query: 195 ---------------------KKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLL 233
K+++ E++ L +++ I+ L+++F D S LY LL
Sbjct: 173 SKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPN-IVKLFYSFHDNSKLYLLL 231
Query: 234 EYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKV 293
+Y P G+L +++HG+++E +YAA+I AL F+H KGV++RDLKPEN LL+ +
Sbjct: 232 QYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHL 291
Query: 294 KLTDFG-TARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCI 352
LTDFG + + + ++ D+ + + S +GT EY +PE+L CD ++ GC+
Sbjct: 292 VLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCL 351
Query: 353 LFQMIAGKPPFKANNEYLTFQKVM------KVQFAFTAGFPMTVRDLVKNILIKNPERR 405
L+ M+ GKPP+ +N + K+ K+ F + G ++D++ +L K +R
Sbjct: 352 LYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEG----MKDILNALLKKETAKR 406
>Hs4758666 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1130
Score = 157 bits (397), Expect = 7e-38
Identities = 130/478 (27%), Positives = 212/478 (44%), Gaps = 78/478 (16%)
Query: 18 ARSVMHRPTPPPIPMELSHPPLPTIRTTDDLSNLSEMKPFGKPNPPVLTKALTDVDN--- 74
A + ++ PPP P L H P++ + +S S+ P K+ +VD+
Sbjct: 547 AEAPNYQGPPPPYPKHLLHQN-PSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDK 605
Query: 75 ----------FISLDPKYLNRRNDSLSS-------------VETIDSTRDDNISIPKELP 111
+ + K RR + S VE + + + K+L
Sbjct: 606 EKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLE 665
Query: 112 ISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLL 171
++ D+ M+ + K++ I + K + F +TLG G++ V L
Sbjct: 666 NEMMRVGLSQDAQDQMRKMLCQ----KESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCL 721
Query: 172 ATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYF 231
A +++ YA K L K+ ++ + +V +V E++ L N + ++ LY++FQD+ +LYF
Sbjct: 722 ARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADN-EWVVRLYYSFQDKDNLYF 780
Query: 232 LLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDM 291
+++Y P GD++SL+ + G E ++Y A++ A+ +H G IHRD+KP+NIL+D D
Sbjct: 781 VMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDG 840
Query: 292 KVKLTDFGTARLLDST-------SEDDLKYDLLTRSN----------------------- 321
+KLTDFG T S D + D + SN
Sbjct: 841 HIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAAR 900
Query: 322 --------SFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQ 373
S VGT Y++PE+L CD W+ G ILF+M+ G+PPF A T
Sbjct: 901 QHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQM 960
Query: 374 KVMKVQFAF----TAGFPMTVRDLVKNILIKNPERRLLIN---QIKAHQFFADVNFGN 424
KV+ Q + A DL+ L + PE RL N +IKAH FF ++F +
Sbjct: 961 KVINWQTSLHIPPQAKLSPEASDLIIK-LCRGPEDRLGKNGADEIKAHPFFKTIDFSS 1017
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 157 bits (397), Expect = 7e-38
Identities = 86/264 (32%), Positives = 155/264 (58%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G+ LG G+++ V LA +I+S K A+K+++KE ++K V ++ E + L+R+++
Sbjct: 74 YELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPY 133
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ +S +YF++EY G+L + + K G + E+ + Y Q+I ++ F H +G
Sbjct: 134 -IVHLFEVMATKSKIYFVMEYVGGGELFNTVAK-GRLPEETARRYFQQLISSVSFCHGRG 191
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+LLD +K++DFG + + + +D L ++F GT Y++PE+
Sbjct: 192 VYHRDLKPENLLLDNKGNLKVSDFGLSAVAEQLRQDGL-------CHTFCGTPAYIAPEV 244
Query: 335 L-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
L Y + D+W+ G ILF ++AG PF N + ++K+ K +F F + L
Sbjct: 245 LTRKGYDAAKADVWSCGVILFVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRL 304
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+ +L NP+ R+ I +I +++F
Sbjct: 305 LTRLLDTNPDTRITIPEIMKNRWF 328
>YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 680
Score = 157 bits (396), Expect = 9e-38
Identities = 87/274 (31%), Positives = 152/274 (54%), Gaps = 13/274 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I+DF + +G GS+ V+ ++ K YA+K + K Y++ + +V + E+ L R+
Sbjct: 344 IDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARV- 402
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ L F+FQ LYF+L + G+L ++K G + ++Y A+++ AL +H
Sbjct: 403 DCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLH 462
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
V++RDLKPENILLD + L DFG +L + +DD ++++F GT EY++
Sbjct: 463 KLDVVYRDLKPENILLDYQGHIALCDFGLCKL--NMKDDD-------KTDTFCGTPEYLA 513
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PELL D W G +L++M+ G PP+ + ++K+++ F GF +
Sbjct: 514 PELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAK 573
Query: 392 DLVKNILIKNPERRLLIN---QIKAHQFFADVNF 422
DL+ +L ++P RRL N +I+ H FF+ +++
Sbjct: 574 DLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSW 607
>Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 495
Score = 157 bits (396), Expect = 9e-38
Identities = 94/292 (32%), Positives = 151/292 (51%), Gaps = 19/292 (6%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESN---KKYAVKILNKEYLIKQKK-VKYVNIEKNT 206
G + F+ LG G Y V ++ K YA+K+L K +++ K + E+N
Sbjct: 76 GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI 135
Query: 207 LQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
L+ +K+ I+ L + FQ LY +LE G+L + + + G E +Y A+I A
Sbjct: 136 LESVKHPF-IVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLA 194
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
LG +H +G+I+RDLKPENI+L +KLTDFG + +S E + +++F GT
Sbjct: 195 LGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCK--ESIHEGAV-------THTFCGT 245
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
EY++PE+L + + D W+ G +++ M+ G PPF A N T K+++ + A
Sbjct: 246 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 305
Query: 387 PMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPP 433
RDLVK L +NP +R+ ++ H FF +N+ + W DPP
Sbjct: 306 TPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPP 357
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 157 bits (396), Expect = 9e-38
Identities = 86/275 (31%), Positives = 158/275 (57%), Gaps = 18/275 (6%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+ F+ TLG GS+ V+L E+ YA+KILNK+ ++K K+V+++ EK LQ + +
Sbjct: 42 DQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI-D 100
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
++ L F+F+D S LY ++EY P G++ S +++ G +E +YAAQ++ A+ ++H
Sbjct: 101 FPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHS 160
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
+IHRDLKPEN+L+D +++TDFG A+ + R+ + GT EY++P
Sbjct: 161 LDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKG------------RTWTLCGTPEYLAP 208
Query: 333 ELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRD 392
E++ + D WA G ++++M G PPF A+ ++K++ + F + ++
Sbjct: 209 EIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKH 268
Query: 393 LVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
L++++L + +R + IK H++FA ++
Sbjct: 269 LLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSW 303
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 157 bits (396), Expect = 9e-38
Identities = 80/255 (31%), Positives = 151/255 (58%), Gaps = 10/255 (3%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DF F + LG G++ V+L + K YA+KIL K+ +I +++V + E LQR K
Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCK 249
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ + L ++FQ++ L F++++A G+L + +RK G+ +E ++Y A+I+ ALG++H
Sbjct: 250 HPF-LTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLH 308
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+++RD+K EN+LLD D +K+ DFG + +++ + ++++F GT EY++
Sbjct: 309 RCDIVYRDMKLENLLLDKDGHIKIADFGLCK-------EEISFG--DKTSTFCGTPEYLA 359
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE+L+D+ D W G ++++M+ G+ PF + + F+ +M F + R
Sbjct: 360 PEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEAR 419
Query: 392 DLVKNILIKNPERRL 406
L+ +L+K+P +RL
Sbjct: 420 TLLTGLLVKDPTQRL 434
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 156 bits (395), Expect = 1e-37
Identities = 87/274 (31%), Positives = 153/274 (55%), Gaps = 13/274 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I+DF + +G GS+ V+ ++ K YA+K L K Y++ + +V + E+ L R+
Sbjct: 341 IDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARV- 399
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ L F+FQ LY +L + G+L ++ G + +++Y A+++ AL +H
Sbjct: 400 DCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLH 459
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
VI+RDLKPENILLD + L DFG +L + ++D ++++F GT EY++
Sbjct: 460 KLDVIYRDLKPENILLDYQGHIALCDFGLCKL--NMKDND-------KTDTFCGTPEYLA 510
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE+L D W G +L++M+ G PP+ N + ++K+++ F GF +
Sbjct: 511 PEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAK 570
Query: 392 DLVKNILIKNPERRLLIN---QIKAHQFFADVNF 422
DL+ +L ++P RRL +N +I+ H FF D+++
Sbjct: 571 DLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISW 604
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 156 bits (395), Expect = 1e-37
Identities = 94/292 (32%), Positives = 154/292 (52%), Gaps = 19/292 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I+DF F LG GS+ V+LA S++ YA+KIL K+ +++ V +EK L
Sbjct: 348 ISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGG 407
Query: 212 NTKG-----IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
G + L+ TFQ LYF++EY GDL+ +++ G E +YAA+I
Sbjct: 408 RGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIG 467
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
L F+H++G+I+RDLK +N++LD + +K+TDFG + +++ TR +F GT
Sbjct: 468 LFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCK-------ENVFPGTTTR--TFCGT 518
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
+Y++PE++ D W+FG +L++M+AG+PPF +E FQ +M+ +
Sbjct: 519 PDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSL 578
Query: 387 PMTVRDLVKNILIKNPERRLLIN-----QIKAHQFFADVNFGNGSVWDKDPP 433
+ K L K+P +RL I+AH FF +++ + PP
Sbjct: 579 SREAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIPPP 630
>CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 580
Score = 156 bits (395), Expect = 1e-37
Identities = 92/279 (32%), Positives = 151/279 (53%), Gaps = 19/279 (6%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLA---TSIESNKKYAVKILNKEYLIK-QKKVKYVNIE 203
++ G DF+ + LG G Y V T ++ + +A+K+L K +++ QK + E
Sbjct: 76 VRVGPEDFQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAE 135
Query: 204 KNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQI 263
+N L+ +K+ I L + FQ LY +LEY G+L + + G E ++Y ++I
Sbjct: 136 RNILEAVKSPF-ICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEI 194
Query: 264 IDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSF 323
+ +L +H +G+I+RDLKPENILLD VKLTDFG + ++++ D ++++F
Sbjct: 195 VVSLEHLHQQGIIYRDLKPENILLDAYGHVKLTDFGLCK-------EEIEGD--QKTHTF 245
Query: 324 VGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT 383
GT EY++PE+L D W+ G ++F M+ G PPF A N T K++K +
Sbjct: 246 CGTIEYMAPEILMRCGHGKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLP 305
Query: 384 AGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFF 417
A RDL+K +L ++ + RL +IK+H FF
Sbjct: 306 AYLSNEARDLIKKLLKRHVDTRLGAGLSDAEEIKSHAFF 344
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 156 bits (394), Expect = 2e-37
Identities = 86/299 (28%), Positives = 163/299 (53%), Gaps = 21/299 (7%)
Query: 135 VPDKQTGKITKQVIKK----GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
VP +T + + + K G+ DF F LG G++ V+LA + YA+K+L KE+
Sbjct: 659 VPSVETSVVAQDLTHKAKRIGLEDFTFLSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEF 718
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKH 248
+++ +V+ EK + +++L+ FQ E+ +YF++++ GDL+ +++
Sbjct: 719 ILENDEVESTKSEKRVFLVANRERHPFLVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQE 778
Query: 249 GSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTS 308
+ + Q+YAA++ AL + HD G+I+RDLK +NILL D VK+ D+G +
Sbjct: 779 -QFSRRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCK------ 831
Query: 309 EDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNE 368
+D+ +D T + F GT E+++PE+L + D WAFG +++QM+ G+ PF+ +E
Sbjct: 832 -EDMWHDNTTAT--FCGTPEFMAPEILLEQQYTRSVDWWAFGVLIYQMLLGQSPFRGEDE 888
Query: 369 YLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
F ++ + + P +++ +L ++P++RL + H FF+++N+
Sbjct: 889 EEIFDAILSDEPLYPIHMPRDSVSILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINW 947
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 155 bits (393), Expect = 2e-37
Identities = 102/344 (29%), Positives = 181/344 (51%), Gaps = 41/344 (11%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF F LG G++ V+LA + K YA+K+L KE ++K ++++ + EK+ +
Sbjct: 569 LDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVAN 628
Query: 212 NTKG--IISLYFTFQDESSLYFLLEYAPNGDLL-SLMRKHGSVNEKCTQYYAAQIIDALG 268
K +++L+ +FQ + +YF++EY GDL+ + R+ SV K ++Y A++ AL
Sbjct: 629 KEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQFSV--KRARFYGAEVCLALK 686
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTAR---LLDSTSEDDLKYDLLTRSNSFVG 325
+ H+ G+ +RDLK +NILL D +++ D+G + LL +T+ ++F G
Sbjct: 687 YFHENGIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTT------------STFCG 734
Query: 326 TAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG 385
T E+++PE+L + D WAFG +++QM+ G+ PFK +E F ++ + F
Sbjct: 735 TPEFMAPEILLEQQYSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPIN 794
Query: 386 FPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPPELGPYKV 440
P L++ +L ++P +RL N++ AH FFA + VWD +L Y+
Sbjct: 795 MPADAVSLLRGLLTRDPNQRLGSGPKDANEVMAHPFFASI------VWDDLYNKL--YEP 846
Query: 441 SARALQSSVPKVASSPAINPIHEPVRQSSVSPKITPKNTTTAQR 484
S + P + +N E +S P +TP NT ++
Sbjct: 847 SYK------PLINDPRDLNNFDEEF--TSACPTLTPVNTVLTRQ 882
>Hs10835242 [T] KOG0614 cGMP-dependent protein kinase
Length = 686
Score = 155 bits (393), Expect = 2e-37
Identities = 85/279 (30%), Positives = 151/279 (53%), Gaps = 19/279 (6%)
Query: 152 INDFKFGETLGDGSYSTV-LLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
++DF +TLG G + V L+ E +K +A+KIL K +++ ++ +++ EK +Q
Sbjct: 372 LSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGA 431
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
++ I+ LY TF+D LY L+E G+L +++R GS + T++Y A +++A ++
Sbjct: 432 -HSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 490
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H KG+I+RDLKPEN++LD KL DFG A+ K ++ +F GT EYV
Sbjct: 491 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAK----------KIGFGKKTWTFCGTPEYV 540
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK--VQFAFTAGFPM 388
+PE++ + D D W+ G ++++++ G PPF + T+ +++ F
Sbjct: 541 APEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAK 600
Query: 389 TVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+L+K + NP RL + I+ H++F N+
Sbjct: 601 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNW 639
>ECU01g1320 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 865
Score = 155 bits (393), Expect = 2e-37
Identities = 90/276 (32%), Positives = 150/276 (53%), Gaps = 21/276 (7%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+D++ + + G Y V L + K YA+K ++KE ++KQ EK +
Sbjct: 43 SDYEIVKNVAKGGYGEVFL---VRREKIYAMKRVSKELVLKQPHTALFMAEKEAMVDCIG 99
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
++ ++ + T QDE LY+L+++ P GD + L+ K + E ++YAA+I+ AL +H
Sbjct: 100 SEWLVCAHMTMQDEEYLYYLMDFIPGGDFMGLLSKEDVLEEDWVRFYAAEIVAALDELHK 159
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
G IHRDLKP+N+L+ +D VKL DFG+ + D RS+ VGT +YVSP
Sbjct: 160 LGWIHRDLKPDNVLIGIDGHVKLADFGSCIKMK---------DGKARSSITVGTPDYVSP 210
Query: 333 ELLNDNYVDFRC------DIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
++L V+ C D W G I+++MI G PF ++ T++++ +V+F F
Sbjct: 211 DVLCS--VNEECEYGEDVDFWTLGVIIYEMIYGTTPFYSDTLMETYRRITRVEFGFPFKV 268
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNF 422
+ L++ LI +RR+ I +IK+H FF V++
Sbjct: 269 SPELTSLIEG-LIAAKDRRMRIEEIKSHAFFEGVDW 303
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 155 bits (393), Expect = 2e-37
Identities = 87/286 (30%), Positives = 151/286 (52%), Gaps = 24/286 (8%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+NDF+ +G GSY+ VL+ + + YA+K++ K + + + +V EK+ +
Sbjct: 258 LNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETAS 317
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N ++ L+ FQ S L+F++E+ GDL+ M++ + E+ ++YAA+I AL F+H
Sbjct: 318 NHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLH 377
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+KG+I+RDLK +N+LLD + +KLTD+G + + D +++F GT Y++
Sbjct: 378 EKGIIYRDLKLDNVLLDHEGHIKLTDYGMCK--EGIRPGD-------TTSTFCGTPNYIA 428
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPF---------KANNEYLTFQKVMKVQFAF 382
PE+L F D WA G +L++M+AG+ PF N E FQ +++
Sbjct: 429 PEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRI 488
Query: 383 TAGFPMTVRDLVKNILIKNPERRL------LINQIKAHQFFADVNF 422
+ ++K L KNP RL I +H FF ++++
Sbjct: 489 PRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDW 534
>7294770 [T] KOG0603 Ribosomal protein S6 kinase
Length = 1207
Score = 155 bits (393), Expect = 2e-37
Identities = 92/286 (32%), Positives = 158/286 (55%), Gaps = 23/286 (8%)
Query: 152 INDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLI-KQKKVKYVNIEKNTL 207
+NDFK LG G+Y V L + ++ K YA+K+LNK ++ K+K ++ E+ L
Sbjct: 258 LNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVL 317
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDAL 267
+ ++ ++SL++ FQ S LY +L++A G+L + + + E + Y A+++ AL
Sbjct: 318 EAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLAL 377
Query: 268 GFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTA 327
+H G+I+RD+K ENILLD + + L+DFG +++L + +E R++SF GT
Sbjct: 378 EQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENE--------YRAHSFCGTL 429
Query: 328 EYVSPELLNDNYV--DFRCDIWAFGCILFQMIAGKPPFKANNEYL----TFQKVMKVQFA 381
EY++PE++ D D W+ G + F+++ G PF ++ + +++ K Q
Sbjct: 430 EYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPM 489
Query: 382 FTAGFPMTVRDLVKNILIKNPERRLLIN-----QIKAHQFFADVNF 422
+ F RD V +L KNP+RRL N +IK H FF +N+
Sbjct: 490 IPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINW 535
Score = 75.1 bits (183), Expect = 5e-13
Identities = 58/223 (26%), Positives = 104/223 (46%), Gaps = 26/223 (11%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+D + G +G+Y T ++ + KI+ + ++ +T N
Sbjct: 621 DDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISCALDTT----N 676
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
K I+S + TF+++ + ++EY +L + +R + C + + Q++ A+ +H
Sbjct: 677 HKNIVSYHGTFREKCETWIVMEYLSGPELTASIRMD---EDSCREIFL-QLVMAVRHIHS 732
Query: 273 KGVIHRDLKPENILLD--VDMKVKLTDFGTARLLD--STSEDDLKYDLLTRSNSFVGTAE 328
K IH DLKPENI+ + D VKL DFG+A + + +D +Y T +
Sbjct: 733 KHFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRY-----------TLD 781
Query: 329 YVSPELLND-NYVDF--RCDIWAFGCILFQMIAGKPPFKANNE 368
Y PE+L D N V + DI+ G L+ M+ G P++ N +
Sbjct: 782 YAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNED 824
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 155 bits (391), Expect = 4e-37
Identities = 86/264 (32%), Positives = 141/264 (52%), Gaps = 13/264 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I F+ G+ LG G + V LA ++ A+K L+K L++ K K V E L+
Sbjct: 115 IGMFEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLR 174
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ K I+ LY F DE +Y +LE+A G+L +R+ +E+ Y Q+ +AL ++H
Sbjct: 175 H-KNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLH 233
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K VIHRD+KPENILL +D ++KL+DFG + S R + GT +Y+
Sbjct: 234 KKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPS-----------NRRTTLCGTLDYLP 282
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFK-ANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE++ + D+W+ G + ++ + G PPF+ + T++++ KV + P
Sbjct: 283 PEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDA 342
Query: 391 RDLVKNILIKNPERRLLINQIKAH 414
RDL+ +L NPE+R+ + Q+ H
Sbjct: 343 RDLISRLLQHNPEKRMSLEQVMRH 366
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 154 bits (389), Expect = 6e-37
Identities = 85/254 (33%), Positives = 138/254 (53%), Gaps = 12/254 (4%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLI-KQKKVKYVNIEKNTLQRLKN 212
DF+ LG GSY VLL + + +A K L K ++ + K ++ E+ L+ +++
Sbjct: 90 DFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVRH 149
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
I LY+ FQD LY +L+YAP G+L S + + + E +Y A++ AL +H
Sbjct: 150 PF-ICRLYYAFQDHDRLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHK 208
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
G+++RDLKPEN LLD + + LTDFG +++ ++ ++ SFVGT EY +P
Sbjct: 209 LGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGAD----------CRSFVGTEEYCAP 258
Query: 333 ELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRD 392
E+L + D D W+ G ++F ++ G PPF ANN +K+ + + RD
Sbjct: 259 EILLEQPYDHAVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIPFYVTSDARD 318
Query: 393 LVKNILIKNPERRL 406
++ L KNP++RL
Sbjct: 319 IINKFLKKNPKQRL 332
>Hs5453978 [T] KOG0614 cGMP-dependent protein kinase
Length = 762
Score = 154 bits (389), Expect = 6e-37
Identities = 93/303 (30%), Positives = 158/303 (51%), Gaps = 37/303 (12%)
Query: 160 TLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISL 219
TLG G + V L N +A+K + K++++ K+ ++V EK L+ L + I+ L
Sbjct: 458 TLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPF-IVKL 516
Query: 220 YFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRD 279
Y TF+D +Y LLE G+L S++R GS +E +++ A + +A ++H G+I+RD
Sbjct: 517 YRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRD 576
Query: 280 LKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNY 339
LKPEN++LD + +KL DFG A+ + S ++ +F GT EYV+PE++ +
Sbjct: 577 LKPENLILDAEGYLKLVDFGFAKKIGSGQ----------KTWTFCGTPEYVAPEVILNKG 626
Query: 340 VDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK--VQFAFTAGFPMTVRDLVKNI 397
DF D W+ G ++++++ G PPF ++ +T+ ++K + F DL++ +
Sbjct: 627 HDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRL 686
Query: 398 LIKNPERRL-----LINQIKAHQFFADVNFG-------------------NGSVWDKDPP 433
+NP RL IN IK H++ N+ + S +DK PP
Sbjct: 687 CRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPP 746
Query: 434 ELG 436
E G
Sbjct: 747 EKG 749
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 154 bits (389), Expect = 6e-37
Identities = 93/288 (32%), Positives = 147/288 (50%), Gaps = 19/288 (6%)
Query: 155 FKFGETLGDGSYSTVLLA---TSIESNKKYAVKILNKEYLIKQKK-VKYVNIEKNTLQRL 210
F+ LG G Y V T + K +A+K+L K +++ K + E+N L+ +
Sbjct: 91 FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEV 150
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
K+ I+ L + FQ LY +LEY G+L + + G E +Y A+I ALG +
Sbjct: 151 KHPF-IVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHL 209
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H KG+I+RDLKPENI+L+ VKLTDFG + +S + T +++F GT EY+
Sbjct: 210 HQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK--ESIHDG-------TVTHTFCGTIEYM 260
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE+L + + D W+ G +++ M+ G PPF N T K++K +
Sbjct: 261 APEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEA 320
Query: 391 RDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPP 433
RDL+K +L +N RL +++AH FF +N+ +PP
Sbjct: 321 RDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 154 bits (388), Expect = 8e-37
Identities = 84/263 (31%), Positives = 144/263 (53%), Gaps = 12/263 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I+DF+ G LG G + V LA +S+ A+K+L K I+++ V++ + +Q
Sbjct: 74 IDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQ-IEKEGVEHQLRREIEIQAHL 132
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ LY F D +Y +LEYAP G+L ++K + +E+ T ++ DAL + H
Sbjct: 133 HHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCH 192
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K VIHRD+KPEN+LL + ++K+ DFG + S R + GT +Y+
Sbjct: 193 GKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPS-----------LRRKTMCGTLDYLP 241
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ + + D+W G + ++++ G PPF++ + T+++++KV F A P +
Sbjct: 242 PEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQ 301
Query: 392 DLVKNILIKNPERRLLINQIKAH 414
DL+ +L NP RL + Q+ AH
Sbjct: 302 DLISKLLRHNPSERLPLAQVSAH 324
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 154 bits (388), Expect = 8e-37
Identities = 85/263 (32%), Positives = 139/263 (52%), Gaps = 12/263 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF+ G LG G + V LA ES+ A+K+L K + K+ + E L+
Sbjct: 6 VDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQ 65
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ LY F D +Y +LEYAP G+L ++K ++E+ T ++ DAL + H
Sbjct: 66 HPN-ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCH 124
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
DK VIHRD+KPEN+LL +VK+ DFG + + L + GT +Y+
Sbjct: 125 DKKVIHRDIKPENLLLGFRGEVKIADFGWS-----------VHTPLPERKTMCGTLDYLP 173
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ D + D+W G + ++++ G PPF++ + T+++++KV F P+ R
Sbjct: 174 PEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGAR 233
Query: 392 DLVKNILIKNPERRLLINQIKAH 414
DL+ +L P RL + QI H
Sbjct: 234 DLISRLLRYQPLERLPLAQILKH 256
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 154 bits (388), Expect = 8e-37
Identities = 110/388 (28%), Positives = 184/388 (47%), Gaps = 32/388 (8%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
+ G LG G+++ V T I + A+K++ K+++ K++ + + + RL
Sbjct: 15 YNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHP 74
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
++ L + ++F++EY G+L ++ + G + E + Y Q+I A+ F H +G
Sbjct: 75 NVVELREVMATKKKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRG 134
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLL-------DSTSEDDLKYDLLTRSNSFVGTA 327
V HRD+KPEN+LLD + +K+TDFG + L+ S DDL L TR GT
Sbjct: 135 VFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDL---LHTR----CGTP 187
Query: 328 EYVSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
YV+PE+L N Y DIW+ G +L+ ++AG PF N + K+ K + F F
Sbjct: 188 AYVAPEVLRNKGYDGAMADIWSCGIVLYALLAGFLPFIDENVMTLYTKIFKAECEFPPWF 247
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKD-----PPELGPYKVS 441
+ ++L+ +L+ +PE+R+ +++IK +F NF + D PPE P K
Sbjct: 248 SLESKELLSRLLVPDPEQRISMSEIKMIPWFRK-NFTPSVAFSIDETIPSPPE-PPTKKK 305
Query: 442 ARALQSSVPKVASSPAINPIHEPVRQSS-------VSPKITPKNTTTAQRPNGDTTS--T 492
+ L AS + N SS K PK T++ P
Sbjct: 306 KKDLNEKEDDGASPRSFNAFQFITSMSSGFDLSNLFEIKRKPKRMFTSKFPAKSVKERLE 365
Query: 493 TTKRELDPRTQRILNNVKKEISQRNHRR 520
T RE+D R + + + K ++ +R R
Sbjct: 366 TAAREMDMRVKHV-KDCKMKLQRRTEGR 392
>Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases
Length = 464
Score = 153 bits (387), Expect = 1e-36
Identities = 89/317 (28%), Positives = 165/317 (51%), Gaps = 33/317 (10%)
Query: 138 KQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKV 197
K+T + + + G++DF+ + +G G++ V L ++ YA+KIL K ++++++V
Sbjct: 73 KETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQV 132
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
++ E++ L ++ ++++FQD+ +LY ++E+ P GD+++L+ K ++ E+ TQ
Sbjct: 133 AHIRAERDILVEADGA-WVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQ 191
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTA------------RLLD 305
+Y ++ + A+ +H G IHRD+KP+N+LLD VKL+DFG R L
Sbjct: 192 FYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLT 251
Query: 306 STSEDDLKYDLLTRSN--------------SFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
D + + S VGT +Y++PE+ + CD W+ G
Sbjct: 252 HNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGV 311
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVM--KVQFAFTAGFPMT--VRDLVKNILIKNPER--R 405
I+++M+ G PPF + T++KVM K F P++ +DL+ I + R
Sbjct: 312 IMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGN 371
Query: 406 LLINQIKAHQFFADVNF 422
+ +IK H FF V++
Sbjct: 372 SGVEEIKGHPFFEGVDW 388
>CE18169 [T] KOG0603 Ribosomal protein S6 kinase
Length = 797
Score = 153 bits (387), Expect = 1e-36
Identities = 92/302 (30%), Positives = 156/302 (51%), Gaps = 21/302 (6%)
Query: 141 GKITKQVIKKGINDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLIKQKKV 197
G + K K F+ + LG GS+ V L + +S YA+K+L K L K +
Sbjct: 90 GDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATL-KVRDR 148
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+ +E+N L + + I+ L++ FQ E LY +L++ GDL + + K E +
Sbjct: 149 QRTKLERNILAHISHPF-IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVK 207
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTAR-LLDSTSEDDLKYDL 316
+Y A++ AL +H G+++RDLKPENILLD D +K+TDFG ++ +DS
Sbjct: 208 FYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEK-------- 259
Query: 317 LTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM 376
++ SF GT EY++PE++N D W+ G ++F+M+ G PF+ + T +++
Sbjct: 260 --KTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL 317
Query: 377 KVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKD 431
K + + + L++ + +N + RL + +IK H FFA ++F + D
Sbjct: 318 KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 377
Query: 432 PP 433
PP
Sbjct: 378 PP 379
Score = 108 bits (271), Expect = 3e-23
Identities = 107/433 (24%), Positives = 195/433 (44%), Gaps = 48/433 (11%)
Query: 54 MKPFGKPNPPVLTKALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPIS 113
+K K P AL+ VD+ DP++ R ++ S I +
Sbjct: 369 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPA--SANGHEIFRGFSFVSN 426
Query: 114 ESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLAT 173
M+ R+ A V+ VP +T T +D++ E +G+G++S V
Sbjct: 427 AVMEERKL------IAKSVRSVPTAKTNPFT--------DDYEILEKIGNGAHSVVHKCQ 472
Query: 174 SIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLL 233
+ +KYAVKI+ K ++V + L R + + ++ L+ ++DE+++Y +
Sbjct: 473 MKATRRKYAVKIVKKAVFDATEEV-------DILLRHSHHQFVVKLFDVYEDETAIYMIE 525
Query: 234 EYAPNGDLLS-LMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVD-- 290
E G+LL L+ K +EK A +++A+ ++H + V HRDL NIL +
Sbjct: 526 ELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDG 585
Query: 291 --MKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWA 348
+++ DFG A+ S +E+ + L+T TA++V+PE+L D CD+W+
Sbjct: 586 DPSSLRIVDFGFAK--QSRAENGM---LMTPCY----TAQFVAPEVLRKQGYDRSCDVWS 636
Query: 349 FGCILFQMIAGKPPFKANNEYLTFQKVMKV---QFAFTAGFPMTV----RDLVKNILIKN 401
G +L M+ G PF Q + +V + + T T+ +DLV+ +L +
Sbjct: 637 LGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVD 696
Query: 402 PERRLLINQIKAHQFFADVN-FGNGSVWDKDPPELGPYKVSARALQSSVPKVASSPAINP 460
P RR+ Q H++ + + + EL V AL+ + +AS+P++
Sbjct: 697 PNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV-ALEQTYKAIASAPSVQ- 754
Query: 461 IHEPVRQSSVSPK 473
PV S+++ +
Sbjct: 755 -LRPVGSSALAKR 766
>CE13014 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 153 bits (387), Expect = 1e-36
Identities = 92/302 (30%), Positives = 156/302 (51%), Gaps = 21/302 (6%)
Query: 141 GKITKQVIKKGINDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLIKQKKV 197
G + K K F+ + LG GS+ V L + +S YA+K+L K L K +
Sbjct: 33 GDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATL-KVRDR 91
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+ +E+N L + + I+ L++ FQ E LY +L++ GDL + + K E +
Sbjct: 92 QRTKLERNILAHISHPF-IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVK 150
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTAR-LLDSTSEDDLKYDL 316
+Y A++ AL +H G+++RDLKPENILLD D +K+TDFG ++ +DS
Sbjct: 151 FYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEK-------- 202
Query: 317 LTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM 376
++ SF GT EY++PE++N D W+ G ++F+M+ G PF+ + T +++
Sbjct: 203 --KTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL 260
Query: 377 KVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKD 431
K + + + L++ + +N + RL + +IK H FFA ++F + D
Sbjct: 261 KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 320
Query: 432 PP 433
PP
Sbjct: 321 PP 322
Score = 108 bits (271), Expect = 3e-23
Identities = 107/433 (24%), Positives = 195/433 (44%), Gaps = 48/433 (11%)
Query: 54 MKPFGKPNPPVLTKALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPIS 113
+K K P AL+ VD+ DP++ R ++ S I +
Sbjct: 312 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPA--SANGHEIFRGFSFVSN 369
Query: 114 ESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLAT 173
M+ R+ A V+ VP +T T +D++ E +G+G++S V
Sbjct: 370 AVMEERKL------IAKSVRSVPTAKTNPFT--------DDYEILEKIGNGAHSVVHKCQ 415
Query: 174 SIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLL 233
+ +KYAVKI+ K ++V + L R + + ++ L+ ++DE+++Y +
Sbjct: 416 MKATRRKYAVKIVKKAVFDATEEV-------DILLRHSHHQFVVKLFDVYEDETAIYMIE 468
Query: 234 EYAPNGDLLS-LMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVD-- 290
E G+LL L+ K +EK A +++A+ ++H + V HRDL NIL +
Sbjct: 469 ELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDG 528
Query: 291 --MKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWA 348
+++ DFG A+ S +E+ + L+T TA++V+PE+L D CD+W+
Sbjct: 529 DPSSLRIVDFGFAK--QSRAENGM---LMTPCY----TAQFVAPEVLRKQGYDRSCDVWS 579
Query: 349 FGCILFQMIAGKPPFKANNEYLTFQKVMKV---QFAFTAGFPMTV----RDLVKNILIKN 401
G +L M+ G PF Q + +V + + T T+ +DLV+ +L +
Sbjct: 580 LGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVD 639
Query: 402 PERRLLINQIKAHQFFADVN-FGNGSVWDKDPPELGPYKVSARALQSSVPKVASSPAINP 460
P RR+ Q H++ + + + EL V AL+ + +AS+P++
Sbjct: 640 PNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV-ALEQTYKAIASAPSVQ- 697
Query: 461 IHEPVRQSSVSPK 473
PV S+++ +
Sbjct: 698 -LRPVGSSALAKR 709
>At4g14350 [R] KOG0605 NDR and related serine/threonine kinases
Length = 475
Score = 153 bits (387), Expect = 1e-36
Identities = 92/332 (27%), Positives = 171/332 (50%), Gaps = 41/332 (12%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
++KD+ K+T + +Q K G +DF+ +G G++ V + + YA+K L K
Sbjct: 19 LLKDLEMKETEYMRRQRHKMGADDFEPLTMIGKGAFGEVRICREKGTGNVYAMKKLKKSE 78
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS 250
++++ +V++V E+N L + ++ I+ LY +FQDE LY ++EY P GD+++L+ + +
Sbjct: 79 MLRRGQVEHVKAERNLLAEV-DSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDT 137
Query: 251 VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSED 310
+ E ++Y + + A+ +H IHRD+KP+N+LLD D +KL+DFG + LD ++
Sbjct: 138 LTEDEARFYIGETVLAIESIHKHNYIHRDIKPDNLLLDKDGHMKLSDFGLCKPLDCSNLQ 197
Query: 311 DLKYDLLTRSN--------------------------------SFVGTAEYVSPELLNDN 338
+ + + + S VGT +Y++PE+L
Sbjct: 198 EKDFTVARNVSGALQSDGRPVATRRTQQEQLLNWQRNRRMLAYSTVGTPDYIAPEVLLKK 257
Query: 339 YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK----VQFAFTAGFPMTVRDLV 394
CD W+ G I+++M+ G PPF +++ T +K++ ++F +DL+
Sbjct: 258 GYGMECDWWSLGAIMYEMLVGFPPFYSDDPMTTCRKIVNWRNYLKFPDEVRLSPEAKDLI 317
Query: 395 KNILIKNPERRL---LINQIKAHQFFADVNFG 423
+L N E+RL ++IK H +F +G
Sbjct: 318 CRLLC-NVEQRLGTKGADEIKGHPWFRGTEWG 348
>YNR047w [R] KOG0610 Putative serine/threonine protein kinase
Length = 893
Score = 153 bits (386), Expect = 1e-36
Identities = 100/308 (32%), Positives = 156/308 (50%), Gaps = 23/308 (7%)
Query: 146 QVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKN 205
Q I G F+ LG G V L ++N+ YA+K+L+K+ +IK+ K+K V E+
Sbjct: 487 QDIMVGPQSFEKIRLLGQGDVGKVFLVREKKTNRVYALKVLSKDEMIKRNKIKRVLTEQE 546
Query: 206 TLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLM--RKHGSVNEKCTQYYAAQI 263
L N I++LY +FQ E LY +EY G+ + RK + E ++YA+++
Sbjct: 547 ILAT-SNHPFIVTLYHSFQSEDYLYLCMEYCMGGEFFRALQTRKTKCICEDDARFYASEV 605
Query: 264 IDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLT----- 318
AL ++H G I+RDLKPENILL + L+DF + + +K +
Sbjct: 606 TAALEYLHLLGFIYRDLKPENILLHQSGHIMLSDFDLSIQAKDSKVPVVKGSAQSTLVDT 665
Query: 319 -------RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLT 371
R+NSFVGT EY++PE++ N D W G ++++M+ G PFK +N T
Sbjct: 666 KICSDGFRTNSFVGTEEYIAPEVIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNET 725
Query: 372 FQKVMK--VQFAFTAGFPMTVRDLVKNILIKNPERRLLIN----QIKAHQFFADVNFGNG 425
F ++K V F T +DL+K +L KN +RL +K H FF V +
Sbjct: 726 FTNILKNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQW--S 783
Query: 426 SVWDKDPP 433
+ +++PP
Sbjct: 784 LLRNQEPP 791
>YCR091w [R] KOG0610 Putative serine/threonine protein kinase
Length = 720
Score = 153 bits (386), Expect = 1e-36
Identities = 98/290 (33%), Positives = 153/290 (51%), Gaps = 20/290 (6%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG G V L ++N+ +A+K+LNK +IK+KK+K V E+ L + I++LY
Sbjct: 330 LGQGDVGKVYLMRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILAT-SDHPFIVTLY 388
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLM--RKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHR 278
+FQ + LY +EY G+ + RK + E+ ++YA++++ AL ++H G I+R
Sbjct: 389 HSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYR 448
Query: 279 DLKPENILL---------DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
DLKPENILL D D+ ++ T + DST D R+NSFVGT EY
Sbjct: 449 DLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEY 508
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM--KVQFAFTAGFP 387
++PE++ N D W G ++++M+ G PFK +N TF ++ V+F
Sbjct: 509 LAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVS 568
Query: 388 MTVRDLVKNILIKNPERRLLIN----QIKAHQFFADVNFGNGSVWDKDPP 433
+DL+K +L KN +RL IK H FF V + + ++DPP
Sbjct: 569 KNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQW--SFLRNQDPP 616
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 153 bits (386), Expect = 1e-36
Identities = 88/285 (30%), Positives = 160/285 (55%), Gaps = 23/285 (8%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
GI DF F +TLG GS+ V L S + YA+K+L K+ ++ K++++ E+ L R+
Sbjct: 197 GIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRV 256
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
++ I L+ TFQD +L+ ++++A G+L SL+RK EK ++YAA++I AL ++
Sbjct: 257 QHPF-ITILWGTFQDAKNLFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYL 315
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H +++RDLKPEN+LLD +K+ DFG A+ + +++ + GT +Y+
Sbjct: 316 HHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSN-----------CCTLCGTPDYL 364
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE+++ + D W+ G ++F+M+AG PPF + N ++ +++ + + + F
Sbjct: 365 APEIISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPAS 424
Query: 391 RDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDK 430
DL+ ++L ++ R I H +F D++ WDK
Sbjct: 425 IDLLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDIS------WDK 463
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 153 bits (386), Expect = 1e-36
Identities = 88/299 (29%), Positives = 165/299 (54%), Gaps = 23/299 (7%)
Query: 139 QTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLI-KQ 194
+T +T K GI +F+ + LG G+Y V L I ++ K YA+K+L K ++ K
Sbjct: 33 RTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKA 92
Query: 195 KKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEK 254
K ++ E+ L+ ++ + +++L++ FQ E+ L+ +L+Y G+L + + + E
Sbjct: 93 KTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEH 152
Query: 255 CTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKY 314
Q Y +I+ AL +H G+I+RD+K ENILLD + V LTDFG ++ +
Sbjct: 153 EVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSK--------EFVA 204
Query: 315 DLLTRSNSFVGTAEYVSPELL--NDNYVDFRCDIWAFGCILFQMIAGKPPF----KANNE 368
D R+ SF GT EY++P+++ D+ D D W+ G ++++++ G PF + N++
Sbjct: 205 DETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQ 264
Query: 369 YLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
++++K + + +DL++ +L+K+P++RL ++IK H FF +N+
Sbjct: 265 AEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINW 323
Score = 128 bits (321), Expect = 5e-29
Identities = 81/273 (29%), Positives = 139/273 (50%), Gaps = 29/273 (10%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG+GS+S +SN+ VKI++K +K E L+ + I+ L+
Sbjct: 432 LGEGSFSICRKCVHKKSNQALQVKIISKRMEANTQK------EITALKLCEGHPNIVKLH 485
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
F D+ + ++E G+L +RK +E Y +++ AL MHD GV+HRDL
Sbjct: 486 EVFHDQLHTFLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHRDL 545
Query: 281 KPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLND 337
KPEN+L + ++++K+ DFG ARL ++ LK T + PELLN
Sbjct: 546 KPENLLFTDENDNLEIKIIDFGFARLKPPDNQ-PLKTPCFTLHS--------CRPELLNQ 596
Query: 338 NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLT-------FQKVMKVQFAFTA----GF 386
N D CD+W+ G IL+ M++G+ PF++++ LT +K+ K F+F
Sbjct: 597 NGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNV 656
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFAD 419
+DL++ +L +P +RL ++ ++ +++ D
Sbjct: 657 SQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQD 689
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 153 bits (386), Expect = 1e-36
Identities = 100/342 (29%), Positives = 174/342 (50%), Gaps = 23/342 (6%)
Query: 103 NISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKG------INDFK 156
N+ +P E SE+ + ++++ +R VP+++T + G + DF
Sbjct: 287 NVPVPPEG--SEANEELRQKF-ERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFN 343
Query: 157 FGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGI 216
F LG GS+ V+L+ +++ YAVKIL K+ +I+ V+ +EK L +
Sbjct: 344 FLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFL 403
Query: 217 ISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVI 276
L+ FQ LYF++EY GDL+ +++ G E +YAA+I L F+ KG+I
Sbjct: 404 TQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGII 463
Query: 277 HRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLN 336
+RDLK +N++LD + +K+ DFG + + +D +T + +F GT +Y++PE++
Sbjct: 464 YRDLKLDNVMLDSEGHIKIADFGMCK--------ENIWDGVT-TKTFCGTPDYIAPEIIA 514
Query: 337 DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKN 396
D WAFG +L++M+AG+ PF+ +E FQ +M+ A+ + K
Sbjct: 515 YQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKG 574
Query: 397 ILIKNPERRLLI-----NQIKAHQFFADVNFGNGSVWDKDPP 433
++ K+P +RL IK H FF +++ + PP
Sbjct: 575 LMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPP 616
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 153 bits (386), Expect = 1e-36
Identities = 100/342 (29%), Positives = 174/342 (50%), Gaps = 23/342 (6%)
Query: 103 NISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKG------INDFK 156
N+ +P E SE+ + ++++ +R VP+++T + G + DF
Sbjct: 287 NVPVPPEG--SEANEELRQKF-ERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFN 343
Query: 157 FGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGI 216
F LG GS+ V+L+ +++ YAVKIL K+ +I+ V+ +EK L +
Sbjct: 344 FLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFL 403
Query: 217 ISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVI 276
L+ FQ LYF++EY GDL+ +++ G E +YAA+I L F+ KG+I
Sbjct: 404 TQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGII 463
Query: 277 HRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLN 336
+RDLK +N++LD + +K+ DFG + + +D +T + +F GT +Y++PE++
Sbjct: 464 YRDLKLDNVMLDSEGHIKIADFGMCK--------ENIWDGVT-TKTFCGTPDYIAPEIIA 514
Query: 337 DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKN 396
D WAFG +L++M+AG+ PF+ +E FQ +M+ A+ + K
Sbjct: 515 YQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKG 574
Query: 397 ILIKNPERRLLI-----NQIKAHQFFADVNFGNGSVWDKDPP 433
++ K+P +RL IK H FF +++ + PP
Sbjct: 575 LMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPP 616
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 152 bits (385), Expect = 2e-36
Identities = 94/294 (31%), Positives = 155/294 (51%), Gaps = 17/294 (5%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
++ G DF +G G++ V L ++N+ YA+K ++K+ ++++K+V + E+N L
Sbjct: 295 VRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNIL 354
Query: 208 QR--LKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIID 265
R L + I+ L F+FQ S LY + +Y G+L ++ G E+ ++Y A+++
Sbjct: 355 VRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVL 414
Query: 266 ALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVG 325
AL +H +I+RDLKPENILLD D + L DFG ++ S + +N+F G
Sbjct: 415 ALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANLSAN---------ATTNTFCG 465
Query: 326 TAEYVSPE-LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTA 384
T EY++PE LL D + D W+ G ++F+M G PF A + ++ + + F
Sbjct: 466 TTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPK 525
Query: 385 G-FPMTVRDLVKNILIKNPERRL----LINQIKAHQFFADVNFGNGSVWDKDPP 433
G R V+ +L +NP RL ++K H FFAD+N+ S PP
Sbjct: 526 GVLSSEGRSFVRGLLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPP 579
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 152 bits (385), Expect = 2e-36
Identities = 89/274 (32%), Positives = 150/274 (54%), Gaps = 20/274 (7%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
D++ + +G G++ V L + K YA+K+L+K +IK+ + E+ + N+
Sbjct: 75 DYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFF-WEERDIMAFANS 133
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
++ L++ FQD+ LY ++EY P GDL++LM + V EK ++Y A+++ AL +H
Sbjct: 134 PWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY-DVPEKWARFYTAEVVLALDAIHSM 192
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
G IHRD+KP+N+LLD +KL DFGT ++ + R ++ VGT +Y+SPE
Sbjct: 193 GFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEG--------MVRCDTAVGTPDYISPE 244
Query: 334 LL----NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
+L D Y CD W+ G L++M+ G PF A++ T+ K+M + + T
Sbjct: 245 VLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDND 304
Query: 390 VRDLVKNIL---IKNPERRL---LINQIKAHQFF 417
+ KN++ + + E RL + +IK H FF
Sbjct: 305 ISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFF 338
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 152 bits (385), Expect = 2e-36
Identities = 87/283 (30%), Positives = 152/283 (52%), Gaps = 10/283 (3%)
Query: 141 GKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYV 200
GKI + K IN+F F + LG GS+ VLL + +A+K L K+ ++ V+
Sbjct: 335 GKIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECT 394
Query: 201 NIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYA 260
+EK L + L TFQ + L+F++E+ GDL+ ++ G +YA
Sbjct: 395 MVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYA 454
Query: 261 AQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRS 320
A+I+ L F+H KG+I+RDLK +N+LLD D +K+ DFG + +++ + +R+
Sbjct: 455 AEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCK-------ENIFGE--SRA 505
Query: 321 NSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQF 380
++F GT +Y++PE+L F D W+FG +L++M+ G+ PF ++E F+ +
Sbjct: 506 STFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTP 565
Query: 381 AFTAGFPMTVRDLVKNILIKNPERRL-LINQIKAHQFFADVNF 422
+ +D+++ + + P +RL + IK H FF +N+
Sbjct: 566 HYPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINW 608
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 152 bits (385), Expect = 2e-36
Identities = 88/302 (29%), Positives = 155/302 (51%), Gaps = 29/302 (9%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
+ I DF+ + + G++ V LA + +A+K+L K +I++ V+ + E+N L
Sbjct: 748 RTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERNILI 807
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
++N ++ +++F +LY ++EY GDL SL+R G ++E + Y A+++ AL
Sbjct: 808 SVRNPF-VVRFFYSFTCRENLYLVMEYLNGGDLFSLLRNLGCLDEDMARIYIAEVVLALE 866
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSF----- 323
++H +IHRDLKP+N+L++ D +KLTDFG +++ S DDL + ++ F
Sbjct: 867 YLHSVNIIHRDLKPDNLLINQDGHIKLTDFGLSKVGLINSTDDLSGESSLGNSGFFAEDG 926
Query: 324 -----------------VGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKAN 366
VGT +Y++PE+L D W+ G ILF+++ G PPF A
Sbjct: 927 SKAQHSQGKDSRKKHAVVGTPDYLAPEILLGMGHGKTADWWSVGVILFEVLVGIPPFNAE 986
Query: 367 NEYLTFQKVMKVQFAF---TAGFPMTVRDLVKNILIKNPERRL---LINQIKAHQFFADV 420
F+ ++ + DL+ +L +NP +RL ++K H FF D+
Sbjct: 987 TPQQIFENIINRDIPWPNVPEEISYEAHDLINKLLTENPVQRLGATGAGEVKQHHFFKDI 1046
Query: 421 NF 422
N+
Sbjct: 1047 NW 1048
>At3g23310 [R] KOG0605 NDR and related serine/threonine kinases
Length = 568
Score = 152 bits (385), Expect = 2e-36
Identities = 100/377 (26%), Positives = 185/377 (48%), Gaps = 51/377 (13%)
Query: 87 NDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQ 146
N V++ ++ + +L +E + QK ++KD+ K+T + +Q
Sbjct: 60 NHYKKQVQSQQQRKERRDMLENKLAAAEVSEEEQKN--------LLKDLEKKETEYMRRQ 111
Query: 147 VIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNT 206
K G +DF+ +G G++ V + + YA+K L K ++++ +V++V E+N
Sbjct: 112 RHKMGTDDFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHVKAERNL 171
Query: 207 LQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
L + ++ I+ LY +FQDE LY ++EY P GD+++L+ + ++ E ++Y + + A
Sbjct: 172 LAEV-DSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLA 230
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLL--------- 317
+ +H IHRD+KP+N+LLD +KL+DFG + LD + + + +
Sbjct: 231 IESIHKHNYIHRDIKPDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQS 290
Query: 318 ---------TRSN----------------SFVGTAEYVSPELLNDNYVDFRCDIWAFGCI 352
TRS S VGT +Y++PE+L CD W+ G I
Sbjct: 291 DGRPVAPRRTRSQMEQLQNWQRNRRMLAYSTVGTPDYIAPEVLLKKGYGMECDWWSLGAI 350
Query: 353 LFQMIAGKPPFKANNEYLTFQKVMK----VQFAFTAGFPMTVRDLVKNILIKNPERRL-- 406
+++M+ G PPF ++ T +K++ ++F +DL+ +L N E+R+
Sbjct: 351 MYEMLVGFPPFYSDEPMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLLC-NVEQRIGT 409
Query: 407 -LINQIKAHQFFADVNF 422
N+IK H +F+ V +
Sbjct: 410 KGANEIKEHPWFSGVEW 426
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 152 bits (384), Expect = 2e-36
Identities = 92/288 (31%), Positives = 154/288 (52%), Gaps = 22/288 (7%)
Query: 142 KITKQV--IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKY 199
KI K++ ++ D+ + +G G++ V L S K YA+K+L+K +IK+ +
Sbjct: 77 KIVKKIKGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAF 136
Query: 200 VNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYY 259
E+ + N+ ++ L++ FQD+ LY ++EY P GDL++LM + V EK ++Y
Sbjct: 137 F-WEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY-DVPEKWAKFY 194
Query: 260 AAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTR 319
A+++ AL +H G+IHRD+KP+N+LLD +KL DFGT +D T +
Sbjct: 195 TAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETG--------MVH 246
Query: 320 SNSFVGTAEYVSPELL----NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKV 375
++ VGT +Y+SPE+L D + CD W+ G L++M+ G PF A++ T+ K+
Sbjct: 247 CDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKI 306
Query: 376 M----KVQFAFTAGFPMTVRDLVKNILIKNPER--RLLINQIKAHQFF 417
M + F A ++L+ L R R + +I+ H FF
Sbjct: 307 MDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFF 354
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 152 bits (384), Expect = 2e-36
Identities = 92/288 (31%), Positives = 154/288 (52%), Gaps = 22/288 (7%)
Query: 142 KITKQV--IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKY 199
KI K++ ++ D+ + +G G++ V L S K YA+K+L+K +IK+ +
Sbjct: 77 KIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAF 136
Query: 200 VNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYY 259
E+ + N+ ++ L++ FQD+ LY ++EY P GDL++LM + V EK ++Y
Sbjct: 137 F-WEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNY-DVPEKWAKFY 194
Query: 260 AAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTR 319
A+++ AL +H G+IHRD+KP+N+LLD +KL DFGT +D T +
Sbjct: 195 TAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETG--------MVH 246
Query: 320 SNSFVGTAEYVSPELL----NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKV 375
++ VGT +Y+SPE+L D + CD W+ G L++M+ G PF A++ T+ K+
Sbjct: 247 CDTAVGTPDYISPEVLKSQGGDGFYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKI 306
Query: 376 M----KVQFAFTAGFPMTVRDLVKNILIKNPER--RLLINQIKAHQFF 417
M + F A ++L+ L R R + +I+ H FF
Sbjct: 307 MDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFF 354
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 152 bits (384), Expect = 2e-36
Identities = 87/283 (30%), Positives = 144/283 (50%), Gaps = 12/283 (4%)
Query: 132 VKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYL 191
V ++P+K+T ++ K INDF+ G LG G + +V LA + + A+K+L K L
Sbjct: 7 VINLPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQL 66
Query: 192 IKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
I V++ + +Q N II LY F D +Y +LEYAP G++ +
Sbjct: 67 ISGG-VEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRF 125
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
+E Y +I DAL + H K VIHRD+KPEN+L+ ++K+ DFG + S
Sbjct: 126 SEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPS----- 180
Query: 312 LKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLT 371
+ + GT +Y+ PE++N D+WA G + ++ + GKPPF+ ++ T
Sbjct: 181 ------NKRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKT 234
Query: 372 FQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAH 414
+ + +F + RDL+ +L+ +P+ R + Q+K H
Sbjct: 235 YAAIKAARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEH 277
>Hs18959200 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 1088
Score = 152 bits (383), Expect = 3e-36
Identities = 98/312 (31%), Positives = 158/312 (50%), Gaps = 49/312 (15%)
Query: 159 ETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIIS 218
+TLG G++ V LA ++++ YA+K L K+ ++ + +V +V E++ L N + ++
Sbjct: 672 KTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVVHVKAERDILAEADN-EWVVK 730
Query: 219 LYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHR 278
LY++FQD+ SLYF+++Y P GD++SL+ + E ++Y A++ A+ +H G IHR
Sbjct: 731 LYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHR 790
Query: 279 DLKPENILLDVDMKVKLTDFGTAR-----------------LLDSTSEDDLKYDLLT--- 318
D+KP+NIL+D+D +KLTDFG DS DL D+
Sbjct: 791 DIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRC 850
Query: 319 ------------------RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGK 360
++S VGT Y++PE+L CD W+ G ILF+M+ G+
Sbjct: 851 GDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQ 910
Query: 361 PPFKANNEYLTFQKVMKVQFAFTAGFPMTV------RDLVKNILIKNPER--RLLINQIK 412
PPF A T KV + + T P V RDL+ + R R + +K
Sbjct: 911 PPFLAPTPTETQLKV--INWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLK 968
Query: 413 AHQFFADVNFGN 424
AH FF+ ++F +
Sbjct: 969 AHPFFSAIDFSS 980
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 152 bits (383), Expect = 3e-36
Identities = 81/263 (30%), Positives = 146/263 (54%), Gaps = 15/263 (5%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF+ G LG G + V LA +S A+K++ KE + K K + E L++
Sbjct: 21 DFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHP 80
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
I+ L+ F D ++ +LEYA G+L +++++G + E+ Y A + AL + H K
Sbjct: 81 N-ILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGK 139
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
VIHRD+KPEN+LLD + ++K+ DFG + + S++ + + GT +Y++PE
Sbjct: 140 CVIHRDIKPENLLLDHEGRLKIADFGWS--VQSSN----------KRKTMCGTLDYLAPE 187
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF--TAGFPMTVR 391
++ + D+ D W G + ++ + G PPF+A ++ TF++++K+ +F T +
Sbjct: 188 MVENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAK 247
Query: 392 DLVKNILIKNPERRLLINQIKAH 414
+L+ +L+K+P +RL I +I H
Sbjct: 248 NLISQLLVKDPSKRLSIEKIMQH 270
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 152 bits (383), Expect = 3e-36
Identities = 84/269 (31%), Positives = 146/269 (54%), Gaps = 8/269 (2%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G+ LG G+++ V A + + AVKILNK+ L+ + + ++ R +
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ +S ++F +E+ G+L + + KHG ++E ++ Y Q+I A+G+ H +G
Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+L+D + +K++DFG + L D D L + L GT YV+PE+
Sbjct: 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTL-------CGTPAYVAPEI 193
Query: 335 LN-DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
L+ Y + D+W+ G +LF ++AG PF N ++K+ K ++ F ++
Sbjct: 194 LSKKGYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRF 253
Query: 394 VKNILIKNPERRLLINQIKAHQFFADVNF 422
V +L NPE R+ I++I +F F
Sbjct: 254 VSRLLDINPETRITIDEILKDPWFVRGGF 282
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 151 bits (382), Expect = 4e-36
Identities = 91/308 (29%), Positives = 154/308 (49%), Gaps = 18/308 (5%)
Query: 111 PISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKK----GINDFKFGETLGDGSY 166
P+S + QK +A ++ P+++ K K + DF+ G LG G +
Sbjct: 87 PVSRPLNNTQKSKQPLPSAP--ENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKF 144
Query: 167 STVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDE 226
V LA +S A+K+L K L K + E L++ I+ LY F D
Sbjct: 145 GNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN-ILRLYGYFHDA 203
Query: 227 SSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENIL 286
+ +Y +LEYAP G + ++K +E+ T Y ++ +AL + H K VIHRD+KPEN+L
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 287 LDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDI 346
L ++K+ DFG + S+ R + GT +Y+ PE++ D + D+
Sbjct: 264 LGSAGELKIADFGWSVHAPSS-----------RRTTLCGTLDYLPPEMIEGRMHDEKVDL 312
Query: 347 WAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL 406
W+ G + ++ + GKPPF+AN T++++ +V+F F RDL+ +L NP +R
Sbjct: 313 WSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRP 372
Query: 407 LINQIKAH 414
++ ++ H
Sbjct: 373 MLREVLEH 380
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 151 bits (382), Expect = 4e-36
Identities = 83/285 (29%), Positives = 152/285 (53%), Gaps = 15/285 (5%)
Query: 143 ITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI 202
++K K +NDF + + LG G++ V+L + + YA+KIL KE +I + +V +
Sbjct: 140 VSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVT 199
Query: 203 EKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQ 262
E LQ ++ + +L + FQ L F++EYA G+L + + E+ ++Y A+
Sbjct: 200 ESRVLQNTRHPF-LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAE 258
Query: 263 IIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNS 322
I+ AL ++H + V++RD+K EN++LD D +K+TDFG + + S+ +
Sbjct: 259 IVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCK--EGISDG-------ATMKT 309
Query: 323 FVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF 382
F GT EY++PE+L DN D W G ++++M+ G+ PF + F+ ++ + F
Sbjct: 310 FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRF 369
Query: 383 TAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+ L+ +L K+P++RL ++ H+FF +N+
Sbjct: 370 PRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINW 414
>CE28760 [R] KOG0605 NDR and related serine/threonine kinases
Length = 467
Score = 151 bits (382), Expect = 4e-36
Identities = 94/330 (28%), Positives = 175/330 (52%), Gaps = 38/330 (11%)
Query: 138 KQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKV 197
K+T + + + +NDF+ + +G G++ V L ++ YA+KIL K ++++++
Sbjct: 63 KETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQT 122
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+V E++ L + ++ +Y++FQD S+LY ++E+ P GD+++L+ K ++ E+ TQ
Sbjct: 123 AHVRAERDILSEA-DCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQ 181
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD------ 311
+Y A+ A+ F+H G IHRD+KP+N+LLD VKL+DFG L D
Sbjct: 182 FYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWP 241
Query: 312 --LKYDLLTR------------------SNSFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
L D +++ + S VGT +Y++PE+ N CD W+ G
Sbjct: 242 STLPPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGV 301
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMKVQ--FAFTAGFPMTV--RDLVKNILIKNPERRL- 406
I+++M+ G PPF + T++KV+ Q F + P+++ + +K + ERRL
Sbjct: 302 IMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCE-AERRLG 360
Query: 407 ---LINQIKAHQFFADVNFGNGSVWDKDPP 433
+++IK F +++ + + ++ PP
Sbjct: 361 NHGGLDEIKQCPFVKRIDWNH--IRERPPP 388
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 151 bits (382), Expect = 4e-36
Identities = 81/279 (29%), Positives = 154/279 (55%), Gaps = 18/279 (6%)
Query: 160 TLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISL 219
T+G G++ V LA + YA+K+LN ++ ++ ++V+ EK L +LK+ I+ +
Sbjct: 68 TIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPF-IVKM 126
Query: 220 YFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRD 279
Y + +D + LY ++E+ P G++ S +R S + ++YA++I+ AL ++H G+++RD
Sbjct: 127 YASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRD 186
Query: 280 LKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNY 339
LKPEN++L + +K+ DFG A+ +L R+ + GT +Y++PE L
Sbjct: 187 LKPENLMLSKEGHIKMADFGFAK------------ELRDRTYTICGTPDYLAPESLARTG 234
Query: 340 VDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILI 399
+ D WA G ++++M+ GKPPF+ + +++ + F F + +DLVK +L
Sbjct: 235 HNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLLE 294
Query: 400 KNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPP 433
+ +R+ +K H++F VN+ + +PP
Sbjct: 295 VDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPP 333
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 151 bits (382), Expect = 4e-36
Identities = 84/272 (30%), Positives = 154/272 (55%), Gaps = 12/272 (4%)
Query: 147 VIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNT 206
V++K + ++ G T+G+G+++ V A + E+ + A+KI+++ +IK+K V + E +
Sbjct: 2 VVRK-VGKYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISI 60
Query: 207 LQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
++ +++ ++ LY + +Y +LEY G+L + ++G ++E + Y Q+ID
Sbjct: 61 MKLVRHPC-VVRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDG 119
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
+ + H KGV HRDLKPEN+LLD +K++DFG + L + +T + GT
Sbjct: 120 VDYCHSKGVYHRDLKPENLLLDSQGNLKISDFGLSALPEQG---------VTILKTTCGT 170
Query: 327 AEYVSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG 385
YV+PE+L + Y DIW+ G IL+ ++AG PF + + K+ K +F+ +
Sbjct: 171 PNYVAPEVLSHKGYNGAVADIWSCGVILYVLMAGYLPFDEMDLPTLYSKIDKAEFSCPSY 230
Query: 386 FPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
F + + L+ IL NPE R+ I +I+ ++F
Sbjct: 231 FALGAKSLINRILDPNPETRITIAEIRKDEWF 262
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 151 bits (381), Expect = 5e-36
Identities = 85/274 (31%), Positives = 150/274 (54%), Gaps = 13/274 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I+ F+ + +G GS+ V+ ++++ YA+K + K +++ + +V + E+ L ++
Sbjct: 227 IDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVN 286
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N I+ L F+FQ LY +L + G+L +++ G + ++Y A+++ AL +H
Sbjct: 287 NPF-IVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLH 345
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+ VI+RDLKPENILLD + L DFG +L + ++ R+N+F GT EY++
Sbjct: 346 EFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTD---------RTNTFCGTPEYLA 396
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PELL + D W G +L++MI G PPF N ++K+++ F +
Sbjct: 397 PELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAK 456
Query: 392 DLVKNILIKNPERRL---LINQIKAHQFFADVNF 422
DL+ +L + PE+RL +IK H FF D+++
Sbjct: 457 DLLSGLLTRAPEKRLGSGGAQEIKNHPFFDDIDW 490
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 151 bits (381), Expect = 5e-36
Identities = 87/283 (30%), Positives = 151/283 (52%), Gaps = 10/283 (3%)
Query: 141 GKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYV 200
GKI + K IN+F F + LG GS+ VLL + A+K L K+ ++ V+
Sbjct: 335 GKIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDDDVECT 394
Query: 201 NIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYA 260
+EK L + L TFQ + L+F++E+ GDL+ ++ G +YA
Sbjct: 395 MVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYA 454
Query: 261 AQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRS 320
A+I+ L F+H KG+I+RDLK +N+LLD D +K+ DFG + +++ + +R+
Sbjct: 455 AEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCK-------ENIFGE--SRA 505
Query: 321 NSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQF 380
++F GT +Y++PE+L F D W+FG +L++M+ G+ PF ++E F+ +
Sbjct: 506 STFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTP 565
Query: 381 AFTAGFPMTVRDLVKNILIKNPERRL-LINQIKAHQFFADVNF 422
+ +D+++ + + P +RL + IK H FF +N+
Sbjct: 566 HYPRWITKESKDILEKLFEREPTKRLGMTGNIKIHPFFKTINW 608
>At5g09890 [R] KOG0605 NDR and related serine/threonine kinases
Length = 495
Score = 151 bits (381), Expect = 5e-36
Identities = 96/341 (28%), Positives = 175/341 (51%), Gaps = 48/341 (14%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
+++++ ++T + Q K GI+DF+ +G G++ V L +++ YA+K L K
Sbjct: 78 MMRNLARRETEYMRLQRRKIGIDDFELLTVIGKGAFGEVRLCRLRSTSEVYAMKKLKKTE 137
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS 250
++ + +V++V E+N L + +++ I+ L+++FQD LY ++EY P GD+++L+ +
Sbjct: 138 MLSRGQVEHVRSERNLLAEV-DSRYIVKLFYSFQDSECLYLIMEYLPGGDIMTLLMREDI 196
Query: 251 VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDS---- 306
++E ++Y A+ I A+ +H +HRD+KP+N++LD +KL+DFG + LD
Sbjct: 197 LSEDVARFYIAESILAIHSIHQHNYVHRDIKPDNLILDKSGHLKLSDFGLCKPLDDKYSS 256
Query: 307 -TSEDD--LKYDLLTRSN----------------------------SFVGTAEYVSPELL 335
EDD L D +S S VGT +Y++PE+L
Sbjct: 257 LLLEDDEMLSQDSENQSGKSDADKAPWQMPKEQLLQWKRNRRALAYSTVGTLDYMAPEVL 316
Query: 336 NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK----VQFAFTAGFPMTVR 391
CD W+ G IL++M+ G PPF +++ +T +K++ ++F R
Sbjct: 317 LKKGYGMECDWWSLGAILYEMLVGYPPFCSDDPRITCRKIINWRVCLKFPEEPKISDEAR 376
Query: 392 DLVKNILIKNPER--RLLINQIKAHQFFADVNFGNGSVWDK 430
DL+ +L R + +IK+H +F G+ WDK
Sbjct: 377 DLICRLLCDVDSRLGTRGVEEIKSHPWF------KGTPWDK 411
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 151 bits (381), Expect = 5e-36
Identities = 82/274 (29%), Positives = 149/274 (53%), Gaps = 9/274 (3%)
Query: 145 KQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEK 204
+Q +K+ + ++ G T+G+G+++ V A + E+ + A+KIL+KE ++K K + + E
Sbjct: 4 RQQVKRRVGKYEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREI 63
Query: 205 NTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQII 264
T++ +K+ ++ LY ++ ++ +LEY G+L + G + E + Y Q+I
Sbjct: 64 ATMKLIKHPN-VVQLYEVMASKTKIFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLI 122
Query: 265 DALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFV 324
A+ + H +GV HRDLKPEN+LLD +K++DFG + L +D L + +
Sbjct: 123 HAVDYCHSRGVYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLH-------TSC 175
Query: 325 GTAEYVSPELLND-NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT 383
GT YV+PE+LND Y D+W+ G +L+ ++AG PF +N ++K+ +F
Sbjct: 176 GTPNYVAPEVLNDRGYDGATADMWSCGVVLYVLLAGYLPFDDSNLMNLYKKISSGEFNCP 235
Query: 384 AGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
+ L+ IL NP R+ ++ ++F
Sbjct: 236 PWLSLGAMKLITRILDPNPMTRVTPQEVFEDEWF 269
>At2g20470 [R] KOG0605 NDR and related serine/threonine kinases
Length = 596
Score = 151 bits (381), Expect = 5e-36
Identities = 95/338 (28%), Positives = 181/338 (53%), Gaps = 41/338 (12%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
++K + K+T + Q K G+ DF +G G++ V + + + YA+K L K
Sbjct: 100 LLKFLEKKETEYMRLQRHKLGVADFDLLTMIGKGAFGEVRVCREKTTGQVYAMKKLKKAE 159
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS 250
++++ +V++V E+N L + ++ I+ LY +FQD+ LY ++EY P GD+++L+ + +
Sbjct: 160 MLRRGQVEHVRAERNLLAEV-DSNYIVKLYCSFQDDDHLYLVMEYLPGGDMMTLLMRKDT 218
Query: 251 VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLD----- 305
+ E+ ++Y A+ + A+ +H IHRD+KP+N+LLD ++L+DFG + LD
Sbjct: 219 LTEEEAKFYVAETVLAIESIHRHNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSAIG 278
Query: 306 ----------------------STSEDDLKY---DLLTRSNSFVGTAEYVSPELLNDNYV 340
T ++ L++ + T + S VGT +Y++PE+L
Sbjct: 279 ENDFSNNSNGSTEQEAGSTAPKRTQQEQLEHWQRNRRTLAYSTVGTPDYIAPEVLLKKGY 338
Query: 341 DFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK----VQFAFTAGFPMTVRDLVKN 396
CD W+ G I+++M+ G PPF +++ T +K++ ++F A +DL+ N
Sbjct: 339 GMECDWWSLGAIMYEMLVGYPPFYSDDPMSTCRKIVNWKSHLKFPEEAILSREAKDLI-N 397
Query: 397 ILIKNPERRL---LINQIKAHQFFADVNFGNGSVWDKD 431
L+ + RRL +++KAH +F V++ +++D D
Sbjct: 398 SLLCSVRRRLGSKGADELKAHTWFETVDW--DTIFDMD 433
>At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1067
Score = 151 bits (381), Expect = 5e-36
Identities = 94/329 (28%), Positives = 178/329 (53%), Gaps = 29/329 (8%)
Query: 124 ADRGAAMIVKDVPDK-QTGKITKQVIKK---GINDFKFGETLGDGSYSTVLLATSIESNK 179
AD+ + +K+ D + T Q++ K I+DF+ + + G++ V LA +
Sbjct: 635 ADKSSVGNIKESEDVLEHASATPQLLLKDRISIDDFEIIKPISRGAFGKVFLARKRTTGD 694
Query: 180 KYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNG 239
+A+K+L K +I++ ++ + E+N L ++ ++ +++F +LY ++EY G
Sbjct: 695 FFAIKVLKKLDMIRKNDIERILQERNILITVRYPF-LVRFFYSFTCRDNLYLVMEYLNGG 753
Query: 240 DLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFG 299
DL SL++K G ++E+ + Y A+++ AL ++H ++HRDLKP+N+L+ + +KLTDFG
Sbjct: 754 DLYSLLQKVGCLDEEIARIYIAELVLALEYLHSLKIVHRDLKPDNLLIAYNGHIKLTDFG 813
Query: 300 TARLLDSTSEDDL---KYDLLTRSNSF---------------VGTAEYVSPELLNDNYVD 341
+++ + DL + D+ R+NS VGT +Y++PE+L
Sbjct: 814 LSKIGLINNTIDLSGHESDVSPRTNSHHFQKNQEEERIRHSAVGTPDYLAPEILLGTEHG 873
Query: 342 FRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM--KVQFAFTAG-FPMTVRDLVKNIL 398
+ D W+ G +LF+++ G PPF A+ F ++ K+ + G +DL+ +L
Sbjct: 874 YAADWWSAGIVLFELLTGIPPFTASRPEKIFDNILNGKMPWPDVPGEMSYEAQDLINRLL 933
Query: 399 IKNPERRLLIN---QIKAHQFFADVNFGN 424
+ PE+RL N ++K+H FF V++ N
Sbjct: 934 VHEPEKRLGANGAAEVKSHPFFQGVDWEN 962
>At1g03920 [R] KOG0605 NDR and related serine/threonine kinases
Length = 569
Score = 151 bits (381), Expect = 5e-36
Identities = 92/329 (27%), Positives = 173/329 (51%), Gaps = 38/329 (11%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
++K + K+T + Q K G +DF+ +G G++ V + I + +A+K L K
Sbjct: 113 LMKFLEKKETEYMRLQRHKMGADDFELLTMIGKGAFGEVRVVREINTGHVFAMKKLKKSE 172
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS 250
++++ +V++V E+N L + ++ I+ LY +FQD LY ++EY P GD+++L+ + +
Sbjct: 173 MLRRGQVEHVRAERNLLAEV-DSNCIVKLYCSFQDNEYLYLIMEYLPGGDMMTLLMRKDT 231
Query: 251 VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLD----- 305
++E ++Y A+ + A+ +H++ IHRD+KP+N+LLD ++L+DFG + LD
Sbjct: 232 LSEDEAKFYIAESVLAIESIHNRNYIHRDIKPDNLLLDRYGHLRLSDFGLCKPLDCSVID 291
Query: 306 -----------------------STSEDDLKYDLLTR---SNSFVGTAEYVSPELLNDNY 339
+ ++ L++ R + S VGT +Y++PE+L
Sbjct: 292 GEDFTVGNAGSGGGSESVSTTPKRSQQEQLEHWQKNRRMLAYSTVGTPDYIAPEVLLKKG 351
Query: 340 VDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK----VQFAFTAGFPMTVRDLVK 395
CD W+ G I+++M+ G PPF A++ T +K++ ++F + RDL+
Sbjct: 352 YGMECDWWSLGAIMYEMLVGYPPFYADDPMSTCRKIVNWKTHLKFPEESRLSRGARDLIG 411
Query: 396 NILIKNPER--RLLINQIKAHQFFADVNF 422
+L +R +QIKAH +F V +
Sbjct: 412 KLLCSVNQRLGSTGASQIKAHPWFEGVQW 440
>Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase
Length = 745
Score = 150 bits (379), Expect = 9e-36
Identities = 93/306 (30%), Positives = 162/306 (52%), Gaps = 25/306 (8%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLA---TSIESNKKYAVKILN 187
+VK++P T + + K F+ + LG GS+ V L T ++ + YA+K+L
Sbjct: 51 VVKEIPI--THHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLK 108
Query: 188 KEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRK 247
K L + +V+ +E++ L + N I+ L++ FQ E LY +L++ GD+ + + K
Sbjct: 109 KASLKVRDRVR-TKMERDILVEV-NHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSK 166
Query: 248 HGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDST 307
E+ ++Y A++ AL +H G+++RDLKPENILLD +KLTDFG ++ +S
Sbjct: 167 EVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSK--ESV 224
Query: 308 SEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANN 367
++ Y SF GT EY++PE++N D W++G ++F+M+ G PF+ +
Sbjct: 225 DQEKKAY-------SFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKD 277
Query: 368 EYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL---LINQIKAHQFFADVNFGN 424
T ++K + + L++ + +NP RL + +IK H FFA+++
Sbjct: 278 RNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFANID--- 334
Query: 425 GSVWDK 430
WDK
Sbjct: 335 ---WDK 337
Score = 103 bits (258), Expect = 9e-22
Identities = 88/339 (25%), Positives = 151/339 (43%), Gaps = 34/339 (10%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ E +G GSYS +N ++AVKI++K ++++ L R
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEI-------LMRYGQHP 478
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
II+L F D +Y + + G+LL + K +E+ I + ++H +G
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQG 538
Query: 275 VIHRDLKPENILLDVDM----KVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
V+HRDLKP NIL + +++ DFG A+ L E+ L LLT TA +V
Sbjct: 539 VVHRDLKPSNILYMDESASADSIRICDFGFAKQL--RGENGL---LLTPCY----TANFV 589
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQFAFTAG- 385
+PE+L D CDIW+ G + + M+AG PF AN T ++++ +F+ + G
Sbjct: 590 APEVLMQQGYDAACDIWSLGVLFYTMLAGYTPF-ANGPNDTPEEILLRIGNGKFSLSGGN 648
Query: 386 ---FPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSA 442
+DL+ ++L +P +R QI H + + D P+
Sbjct: 649 WDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWIT-----HRDQLPNDQPKRNDVSHVV 703
Query: 443 RALQSSVPKVASSPAINPIHEPVRQSSVSPKITPKNTTT 481
+ + + P+ EPV SS++ + + K T+
Sbjct: 704 KGAMVATYSALTHKTFQPVLEPVAASSLAQRRSMKKRTS 742
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 150 bits (379), Expect = 9e-36
Identities = 93/288 (32%), Positives = 156/288 (53%), Gaps = 23/288 (7%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNK-EYLIKQKKVKYVNIEK 204
K + +F LG G+Y V L + + N YA+K+L K L KQK +++ E+
Sbjct: 11 KVSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAER 70
Query: 205 NTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQII 264
L+RL+ T +++L++ FQ ++ L+ ++EY G+L + + G + + ++ A+++
Sbjct: 71 QVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELV 130
Query: 265 DALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFV 324
A+ +H + VI+RDLK ENILLD + VKLTDFG ++L L R+NS+
Sbjct: 131 VAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGE--------LDRANSYC 182
Query: 325 GTAEYVSPELLN---DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFA 381
GT EY+SPE++N Y D D W+ G I F+++ G PF + + + + K
Sbjct: 183 GTIEYMSPEVINRPEGGYSDV-VDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMT 241
Query: 382 FTAGFPMTV----RDLVKNILIKNPERRLLIN---QIKAHQFFADVNF 422
FP T+ RD + +L K E+RL N +IK H+F + +++
Sbjct: 242 KKVPFPKTMDVDARDFIGQLLEKKLEKRLGYNGVDEIKNHKFMSSIDW 289
Score = 129 bits (323), Expect = 3e-29
Identities = 79/284 (27%), Positives = 149/284 (51%), Gaps = 34/284 (11%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG G++S V + ++AVKI+++++ + ++ E L+ ++ I+ L+
Sbjct: 388 LGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQAQR------EARILEMVQGHPNIVQLH 441
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
D Y ++E +LL +RK E Q++ A+ ++HDK ++HRDL
Sbjct: 442 DVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHRDL 501
Query: 281 KPENIL---LDVDMKVKLTDFGTARLLDSTSEDDLK--------YDLLTRSNSFVG---- 325
KPENIL +D +++L DFG ARLL ++ E LK Y L+ ++S
Sbjct: 502 KPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPC 561
Query: 326 -TAEYVSPELLN--DNYVDF--RCDIWAFGCILFQMIAGKPPFKANNEYLT----FQKVM 376
T +Y +PE+L+ D+ ++ +CD+W+ G +LF M++G+ PF A + + Q++
Sbjct: 562 FTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRIC 621
Query: 377 KVQFAFT----AGFPMTVRDLVKNILIKNPERRLLINQIKAHQF 416
+ +F+FT ++L+ +L +P++RL + ++ AH +
Sbjct: 622 RAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTAHMW 665
>Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases
Length = 465
Score = 150 bits (378), Expect = 1e-35
Identities = 86/317 (27%), Positives = 171/317 (53%), Gaps = 33/317 (10%)
Query: 138 KQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKV 197
K+T + + + G+ DF+ + +G G++ V L ++ YA+KIL K ++++++V
Sbjct: 72 KETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQV 131
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
++ E++ L ++ ++ ++++FQD+ +LY ++E+ P GD+++L+ K ++ E+ TQ
Sbjct: 132 GHIRAERDILVEA-DSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQ 190
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTA------------RLLD 305
+Y A+ + A+ +H G IHRD+KP+N+LLD VKL+DFG R L+
Sbjct: 191 FYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLN 250
Query: 306 STSEDDLKYDLLTRSN--------------SFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
+ D + + S VGT +Y++PE+ + CD W+ G
Sbjct: 251 HSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGV 310
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIK---NPERRL-- 406
I+++M+ G PPF + T++KVM + T + + + K+++++ E R+
Sbjct: 311 IMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGA 370
Query: 407 -LINQIKAHQFFADVNF 422
+ +IK++ FF V++
Sbjct: 371 PGVEEIKSNSFFEGVDW 387
>CE03979 [T] KOG0614 cGMP-dependent protein kinase
Length = 581
Score = 149 bits (377), Expect = 1e-35
Identities = 87/276 (31%), Positives = 155/276 (55%), Gaps = 17/276 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ D + TLG G + V L S S++ YA+KI+NK ++++ K+ +V E+ L +
Sbjct: 271 LEDLQRVSTLGMGGFGRVELVRSA-SSRTYALKIMNKAHIVETKQESHVVSERRILMQCD 329
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N I+ +Y T++D +Y L+E G++ +++RK G + T++Y A ++AL ++H
Sbjct: 330 NDY-IVRMYKTYRDSEKIYMLMEPCLGGEIWTILRKKGRFDNDLTRFYCAGAMEALEYLH 388
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K +++RDLKPEN+LLD + KL DFG A+ L + R+ +F GTAEYV+
Sbjct: 389 RKNIVYRDLKPENMLLDRNGWPKLVDFGFAKKLKNGG----------RTWTFCGTAEYVA 438
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK--VQFAFTAGFPMT 389
PE++ + D DIWA G + +++ G PPF + + +T+ ++K ++A+
Sbjct: 439 PEIVLNKGHDLSVDIWALGIFMCELLTGSPPFSSTDPMVTYNAILKGLEKWAWPRFVTKE 498
Query: 390 VRDLVKNILIKNPERRL---LINQIKAHQFFADVNF 422
D++ ++ P RL I +I+ H +F + +F
Sbjct: 499 AIDMMLSLCKYEPTERLGFGDIGEIRHHIWFDNFDF 534
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 149 bits (376), Expect = 2e-35
Identities = 86/300 (28%), Positives = 159/300 (52%), Gaps = 22/300 (7%)
Query: 135 VPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNK-EYLIK 193
VP K + K +IK + ++ TLG G+++ V LA + S K YA+KI+NK + L+
Sbjct: 147 VPVKHSRDSQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLT 206
Query: 194 QKKVKYVNIEKNTLQRLKNTK--GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
+ + + + + LK+ G++ + F+++ L+ ++EY GDL+ + +GS+
Sbjct: 207 SSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFLIANGSI 266
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
+E+ + Q+++ L +H +GV HRD+KPENIL+ D +K++DFG A+++ T
Sbjct: 267 DEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGTG--- 323
Query: 312 LKYDLLTRSNSFVGTAEYVSPELLN------DNYVDFRCDIWAFGCILFQMIAGKPPFKA 365
T +F GT Y++PE+L D D + DIW+ GC+L+ M+ PF +
Sbjct: 324 ------TFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFAS 377
Query: 366 NNEYLTFQKVMKVQFAFTAGFPMTVR----DLVKNILIKNPERRLLINQIKAHQFFADVN 421
+++ + + K + + DL+ +L NPE+R+ ++ H +F V+
Sbjct: 378 SSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRISESEALQHPWFYTVS 437
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 149 bits (376), Expect = 2e-35
Identities = 86/276 (31%), Positives = 141/276 (50%), Gaps = 12/276 (4%)
Query: 139 QTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVK 198
Q K+ Q + DF+ G LG G + V LA +S A+K+L K L K
Sbjct: 116 QNRKMKNQKEAVALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEH 175
Query: 199 YVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQY 258
+ E L++ I+ LY F D + +Y +LEYAP G + ++K +E+ T
Sbjct: 176 QLRREVEIQSHLRHPN-ILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTAN 234
Query: 259 YAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLT 318
+I +AL + H K VIHRD+KPEN+LL ++K+ DFG + S+
Sbjct: 235 LYNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSS----------- 283
Query: 319 RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKV 378
R + GT +Y+ PE++ D + D+W+ G + ++ + GKPPF+AN T++++ +V
Sbjct: 284 RRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRV 343
Query: 379 QFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAH 414
+F F RDL+ +L NP +R ++ ++ H
Sbjct: 344 EFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEH 379
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 149 bits (376), Expect = 2e-35
Identities = 77/260 (29%), Positives = 137/260 (52%), Gaps = 10/260 (3%)
Query: 158 GETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGII 217
G+ LG G ++ T + +NK YA KI+ + K + + ++ E L R+ + K ++
Sbjct: 85 GKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIE-LHRILHHKHVV 143
Query: 218 SLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIH 277
Y F+D+ ++Y LLEY + +++ + E +YY QI+ L ++H++ ++H
Sbjct: 144 QFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILH 203
Query: 278 RDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLND 337
RDLK N ++ M++K+ DFG A L+ R + GT Y+SPE+LN
Sbjct: 204 RDLKLGNFFINEAMELKVGDFGLAARLEPLEH---------RRRTICGTPNYLSPEVLNK 254
Query: 338 NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNI 397
DIWA GC+++ M+ G+PPF+ N T++ + + ++ + + L+ ++
Sbjct: 255 QGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASM 314
Query: 398 LIKNPERRLLINQIKAHQFF 417
L KNPE R ++ I H FF
Sbjct: 315 LSKNPEDRPSLDDIIRHDFF 334
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 149 bits (376), Expect = 2e-35
Identities = 80/267 (29%), Positives = 149/267 (54%), Gaps = 9/267 (3%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ +++ G TLG+GS++ V A + + + A+KIL++E + + K V+ + E +T++ +K
Sbjct: 16 VGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKLIK 75
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ ++ + ++ +Y +LE G+L + + G + E + Y Q+I+A+ + H
Sbjct: 76 HPN-VVEIIEVMASKTKIYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVDYCH 134
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+GV HRDLKPEN++LD + +K++DFG + ED L + + GT YV+
Sbjct: 135 SRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLH-------TACGTPNYVA 187
Query: 332 PELLND-NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE+L+D Y D+W+ G ILF ++AG PF N ++++ K +F+ F
Sbjct: 188 PEVLSDKGYDGAAADVWSCGVILFVLMAGYLPFDEPNLMTLYKRICKAEFSCPPWFSQGA 247
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
+ ++K IL NP R+ I ++ ++F
Sbjct: 248 KRVIKRILEPNPITRISIAELLEDEWF 274
>SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 646
Score = 149 bits (375), Expect = 3e-35
Identities = 86/291 (29%), Positives = 162/291 (55%), Gaps = 17/291 (5%)
Query: 151 GINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
G +DF + +G G++ V L ++ + YA+K+L+K+ ++++K+V + E++ L +
Sbjct: 262 GPDDFVPLKLIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIVRRKEVAHTVGERDILVQT 321
Query: 211 K--NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
++ I++L F+FQ LY + +Y G+L ++K E+ ++Y A+++ AL
Sbjct: 322 SAADSPFIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQ 381
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
+H +G+++RDLKPENILLDV + L DFG ++ S T + +F GT +
Sbjct: 382 ALHKRGIVYRDLKPENILLDVQGHIALCDFGLSKANLSVG---------TTTRTFCGTTD 432
Query: 329 YVSPE-LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG-F 386
Y++PE +L++ D D W+ G +L++M G PF A+N ++ ++ + F G
Sbjct: 433 YLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGLL 492
Query: 387 PMTVRDLVKNILIKNPERRL----LINQIKAHQFFADVNFGNGSVWDKDPP 433
+ RDL+K +L +NP+ RL + ++ H FF +++ + + PP
Sbjct: 493 SVEARDLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWKKLAAKEISPP 543
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 149 bits (375), Expect = 3e-35
Identities = 80/260 (30%), Positives = 146/260 (55%), Gaps = 15/260 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DF F + LG G++ V+L + K YA+KIL K+ +I +++V + E LQR K
Sbjct: 190 MEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLTENRVLQRCK 249
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVN-----EKCTQYYAAQIIDA 266
+ + L ++FQ L F++E+A GDL + + +N E ++Y ++I+ A
Sbjct: 250 HPF-LTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGSEIVLA 308
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
LG++H +++RDLK EN+LLD D +K+ DFG + +++ + ++++F GT
Sbjct: 309 LGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCK-------EEISFG--DKTSTFCGT 359
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
EY++PE+L+D+ D W G ++++M+ G+ PF + + F+ +M F +
Sbjct: 360 PEYLAPEVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKL 419
Query: 387 PMTVRDLVKNILIKNPERRL 406
R L+ +L+K+P +RL
Sbjct: 420 SQEARTLLTGLLVKDPTQRL 439
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 149 bits (375), Expect = 3e-35
Identities = 84/264 (31%), Positives = 147/264 (54%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
+ G LG G+++ V SI +N+ A+K+++KE ++K ++ + E + + R+
Sbjct: 12 YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVM-RIARHP 70
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
++ LY ++ +YF++EY G+L + + K G + + Y Q+I+A+ F H +
Sbjct: 71 NVVELYEVMATKTRIYFVMEYCKGGELFNKVAK-GKLRDDVAWKYFYQLINAVDFCHSRE 129
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRD+KPEN+LLD + +K++DFG + L D +D L + + GT YV+PE+
Sbjct: 130 VYHRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLH-------TTCGTPAYVAPEV 182
Query: 335 LN-DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+N Y + DIW+ G +LF ++AG PF +N ++K+ K F + F VR L
Sbjct: 183 INRKGYDGTKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRL 242
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+ +L NPE R+ I +I+ +F
Sbjct: 243 LCKMLDPNPETRITIARIRESSWF 266
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 149 bits (375), Expect = 3e-35
Identities = 91/319 (28%), Positives = 157/319 (48%), Gaps = 23/319 (7%)
Query: 138 KQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKV 197
K KIT V+ + ++ G LG GS++ V +A SI + + A+KI++K+ I
Sbjct: 7 KSPEKITGTVL---LGKYELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGME 63
Query: 198 KYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+ E ++RL N ++ ++ +S +Y ++EYA G+L + + + G +NE +
Sbjct: 64 PRIIREIEAMRRLHNHPNVLKIHEVMATKSKIYLVVEYAAGGELFTKLIRFGRLNESAAR 123
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLL 317
Y Q+ AL F H G+ HRD+KP+N+LLD +K++DFG + L + S + L +
Sbjct: 124 RYFQQLASALSFCHRDGIAHRDVKPQNLLLDKQGNLKVSDFGLSALPEHRSNNGLLH--- 180
Query: 318 TRSNSFVGTAEYVSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM 376
+ GT Y +PE++ Y + D W+ G LF ++AG PF N ++K+
Sbjct: 181 ----TACGTPAYTAPEVIAQRGYDGAKADAWSCGVFLFVLLAGYVPFDDANIVAMYRKIH 236
Query: 377 KVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELG 436
K + F + R ++ +L NPE R+ I + G+VW + E+
Sbjct: 237 KRDYRFPSWISKPARSIIYKLLDPNPETRMSIEAVM------------GTVWFQKSLEIS 284
Query: 437 PYKVSARALQSSVPKVASS 455
++ S L + K A S
Sbjct: 285 EFQSSVFELDRFLEKEAKS 303
>7295638 [T] KOG0603 Ribosomal protein S6 kinase
Length = 911
Score = 149 bits (375), Expect = 3e-35
Identities = 92/292 (31%), Positives = 155/292 (52%), Gaps = 27/292 (9%)
Query: 145 KQVIKKGIN-----DFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLIKQKK 196
K+VIK+G + F+ LG+GS+ V L I ++ YA+K+L K L + +
Sbjct: 184 KEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDR 243
Query: 197 VKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCT 256
V+ N E+ L + + I+ L++ FQ LY +L++ GDL + + K E+
Sbjct: 244 VRSTN-ERKILADVGHAF-IVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDV 301
Query: 257 QYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARL-LDSTSEDDLKYD 315
++Y A++ A+ +H G+I+RDLKPENILLD + LTDFG ++ LD
Sbjct: 302 KFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDG--------- 352
Query: 316 LLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKV 375
+++ SF GT EY++PE++N DF D W+FG ++++M+ G PF T ++
Sbjct: 353 --SKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQI 410
Query: 376 MKVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
++ + + L++ + +NP+ RL I IKAH FFA +++
Sbjct: 411 LRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDW 462
Score = 105 bits (261), Expect = 4e-22
Identities = 75/279 (26%), Positives = 133/279 (46%), Gaps = 22/279 (7%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI--EKNTLQRLK 211
++ + LG G++S L S K YAVK++ K + + E + R
Sbjct: 567 EYNLLQELGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIMLRYG 626
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N I++LY ++D S Y ++E G+LL + G + E I A+ ++H
Sbjct: 627 NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQMCESEASAVLRTIASAVAYLH 686
Query: 272 DKGVIHRDLKPENILL----DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTA 327
+ GV+HRDLKP N++ +KL D G A+ L +++ L L+T TA
Sbjct: 687 EHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQL--RADNGL---LMTPCY----TA 737
Query: 328 EYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKA---NNEYLTFQKVMKVQFAFTA 384
+V+PE+L D CDIW+ G +L+ M++G+ PF + ++ + +++ Q FT+
Sbjct: 738 NFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTS 797
Query: 385 G----FPMTVRDLVKNILIKNPERRLLINQIKAHQFFAD 419
+ ++L++ +L PE R +I H + +
Sbjct: 798 SRWALISVPAKELLRQMLHIVPENRPTAARILEHDWLRE 836
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 148 bits (374), Expect = 3e-35
Identities = 89/278 (32%), Positives = 150/278 (53%), Gaps = 19/278 (6%)
Query: 153 NDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQR 209
+ F+ + LG GS+ V L I ++ + YA+K+L K L + +V+ +E++ L
Sbjct: 66 SQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVR-TKMERDILVE 124
Query: 210 LKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGF 269
+ N I+ L++ FQ E LY +L++ GDL + + K E+ ++Y A++ AL
Sbjct: 125 V-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 183
Query: 270 MHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
+H G+I+RDLKPENILLD + +KLTDFG L S D K ++ SF GT EY
Sbjct: 184 LHSLGIIYRDLKPENILLDEEGHIKLTDFG----LSKESIDHEK-----KAYSFCGTVEY 234
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
++PE++N D W+FG ++F+M+ G PF+ + T ++K +
Sbjct: 235 MAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPE 294
Query: 390 VRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+ L++ + +NP RL + +IK H FF+ +++
Sbjct: 295 AQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 332
Score = 100 bits (250), Expect = 8e-21
Identities = 96/346 (27%), Positives = 163/346 (46%), Gaps = 49/346 (14%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ E +G GSYS +N ++AVKI++K K+ + + I L R
Sbjct: 422 YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKS---KRDPTEEIEI----LLRYGQHP 474
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
II+L + D +Y + E G+LL + + +E+ I + ++H +G
Sbjct: 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQG 534
Query: 275 VIHRDLKPENILLDVD-----MKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
V+HRDLKP NIL VD +++ DFG A+ L +E+ L L+T TA +
Sbjct: 535 VVHRDLKPSNILY-VDESGNPESIRICDFGFAKQL--RAENGL---LMTPCY----TANF 584
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQFAFTAG 385
V+PE+L D CDIW+ G +L+ M+ G PF AN T ++++ +F+ + G
Sbjct: 585 VAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPF-ANGPDDTPEEILARIGSGKFSLSGG 643
Query: 386 F----PMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVS 441
+ T +DLV +L +P +RL + H + WD +L Y+++
Sbjct: 644 YWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVH--------WD----QLPQYQLN 691
Query: 442 ARALQSSV--PKVASSPAIN----PIHEPVRQSSVSPKITPKNTTT 481
+ V A+ A+N P+ EPV +S+++ + K T+
Sbjct: 692 RQDAPHLVKGAMAATYSALNRNQSPVLEPVGRSTLAQRRGIKKITS 737
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 148 bits (374), Expect = 3e-35
Identities = 90/332 (27%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 147 VIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNT 206
V K + F + LG GS+ V+L N+ YA+K L K+ +++ + IE+
Sbjct: 230 VKKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRV 289
Query: 207 LQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
L + L+ +FQ L+F++EY GDL+ +++ +E T++YA +I+ A
Sbjct: 290 LILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVA 349
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
L F+H +I+RDLK +N+LLD D +KL DFG A+ + E+ + +++F GT
Sbjct: 350 LQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAK-TEMNRENGM-------ASTFCGT 401
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
+Y+SPE++ + D W+FG ++++M+ G+ PF E F ++ + F
Sbjct: 402 PDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTI 461
Query: 387 PMTVRDLVKNILIKNPERRLLINQ-----IKAHQFFADVNFGNGSVWDKDPPELGPYKVS 441
+ + +NP RL + + I+ H FF V++ PP K +
Sbjct: 462 SKEAAKCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSN 521
Query: 442 ARALQSSVPKVASSPAINPIHEPVRQSSVSPK 473
+ A A+ P+H+ +S+ P+
Sbjct: 522 SDASNFDDDFTNEKAALTPVHDKNLLASIDPE 553
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 148 bits (374), Expect = 3e-35
Identities = 90/332 (27%), Positives = 161/332 (48%), Gaps = 13/332 (3%)
Query: 147 VIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNT 206
V K + F + LG GS+ V+L N+ YA+K L K+ +++ + IE+
Sbjct: 367 VKKFALPHFNLLKVLGKGSFGKVMLVELKGKNEFYAMKCLKKDVILEDDDTECTYIERRV 426
Query: 207 LQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
L + L+ +FQ L+F++EY GDL+ +++ +E T++YA +I+ A
Sbjct: 427 LILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVA 486
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
L F+H +I+RDLK +N+LLD D +KL DFG A+ + E+ + +++F GT
Sbjct: 487 LQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAK-TEMNRENGM-------ASTFCGT 538
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
+Y+SPE++ + D W+FG ++++M+ G+ PF E F ++ + F
Sbjct: 539 PDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTI 598
Query: 387 PMTVRDLVKNILIKNPERRLLINQ-----IKAHQFFADVNFGNGSVWDKDPPELGPYKVS 441
+ + +NP RL + + I+ H FF V++ PP K +
Sbjct: 599 SKEAAKCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDWKRFENRQVPPPFKPNIKSN 658
Query: 442 ARALQSSVPKVASSPAINPIHEPVRQSSVSPK 473
+ A A+ P+H+ +S+ P+
Sbjct: 659 SDASNFDDDFTNEKAALTPVHDKNLLASIDPE 690
>7293735 [R] KOG0605 NDR and related serine/threonine kinases
Length = 459
Score = 148 bits (373), Expect = 4e-35
Identities = 91/340 (26%), Positives = 170/340 (49%), Gaps = 51/340 (15%)
Query: 66 TKALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWAD 125
TKA ++N+ S R L+ +E +D+++S QR++K
Sbjct: 25 TKAKVTLENYYSNLVTQYGERKQRLAKLEA--QLKDESLS---------EAQRQEKRLQH 73
Query: 126 RGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKI 185
K+T + + ++ G+ DF+ + +G G++ V L ++ YA+K+
Sbjct: 74 A----------QKETEYLRLKRLRLGVEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKV 123
Query: 186 LNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLM 245
L K ++++++V +V E++ L + + ++ +Y++FQD +LY ++E+ P GD+++L+
Sbjct: 124 LRKADMLEKEQVAHVRAERDVLVEADH-QWVVKMYYSFQDPVNLYLIMEFLPGGDMMTLL 182
Query: 246 RKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLD 305
K +++E+ TQ+Y ++ A+ +H G IHRD+KP+N+LLD +KL+DFG L
Sbjct: 183 MKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIKPDNLLLDARGHLKLSDFGLCTGLK 242
Query: 306 STSEDDLKYDLLTR-----------------------------SNSFVGTAEYVSPELLN 336
+ D DL + S VGT +Y++PE+
Sbjct: 243 KSHRTDFYRDLSQAKPSDFIGTCASPMDSKRRAESWKRNRRALAYSTVGTPDYIAPEVFL 302
Query: 337 DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM 376
CD W+ G I+++M+ G PPF ++N T++KVM
Sbjct: 303 QTGYGPACDWWSLGVIMYEMLMGYPPFCSDNPQDTYRKVM 342
>7293249 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1390
Score = 148 bits (373), Expect = 4e-35
Identities = 90/296 (30%), Positives = 158/296 (52%), Gaps = 20/296 (6%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
++ + DF F + +G G++ V L S++ YA+K L+K ++K+ + E++ +
Sbjct: 80 LRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIM 139
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDAL 267
N++ I+ L+F FQD LY ++++ P GD++SLM + + EK +Y +++ AL
Sbjct: 140 AHA-NSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDY-DIPEKWAIFYTMEVVLAL 197
Query: 268 GFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTA 327
+H+ G +HRD+KP+N+LLD +KL DFGT + + + S++ VGT
Sbjct: 198 DTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQ--------VVSSNAVGTP 249
Query: 328 EYVSPELLN----DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQ 379
+Y+SPE+L DN CD W+ G L++M+ G+ PF A++ T+ K+M +
Sbjct: 250 DYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLS 309
Query: 380 FAFTAGFPMTVRDLVKNILIKNPER--RLLINQIKAHQFFADVNFGNGSVWDKDPP 433
F + L++ L +R R I IKAH FF + + ++ + PP
Sbjct: 310 FPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPP 365
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 147 bits (372), Expect = 6e-35
Identities = 82/264 (31%), Positives = 148/264 (56%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G+ LG G+++ V A +++ A+K+++KE ++K + + E + ++ L++
Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ +S +YF++E+ G+L + + G + E + Y Q++ A+ F H +G
Sbjct: 72 -IVELHEVMATKSKIYFVMEHVKGGELFNKVST-GKLREDVARKYFQQLVRAVDFCHSRG 129
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+LLD +K++DFG + L DS +D L + + GT YV+PE+
Sbjct: 130 VCHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLH-------TTCGTPAYVAPEV 182
Query: 335 LNDN-YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
++ N Y F+ D+W+ G ILF ++AG PF+ +N ++K+ K + F + L
Sbjct: 183 ISRNGYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRL 242
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+K IL NP R+ +I +F
Sbjct: 243 LKRILDPNPNTRVSTEKIMKSSWF 266
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 147 bits (372), Expect = 6e-35
Identities = 84/267 (31%), Positives = 149/267 (55%), Gaps = 10/267 (3%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++ ++ G+ LG GS++ V LA +I S + A+K+++KE ++K ++ E + L+R++
Sbjct: 54 MDKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVR 113
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ L ++ +Y ++EY G+L + + + G + E + Y Q+I ++ F H
Sbjct: 114 HPY-IVHLLEVMATKTKIYIVMEYVRGGELYNTVAR-GRLREGTARRYFQQLISSVAFCH 171
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+GV HRDLK EN+LLD VK++DFG + + + ++ + +F GT Y++
Sbjct: 172 SRGVYHRDLKLENLLLDDKGNVKVSDFGLSVVSEQLKQEGI-------CQTFCGTPAYLA 224
Query: 332 PELLN-DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE+L Y + DIW+ G ILF ++AG PF N + + K+ K QF F +
Sbjct: 225 PEVLTRKGYEGAKADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPEL 284
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
LV +L NP+ R+ I +I H++F
Sbjct: 285 ARLVTRMLDTNPDTRITIPEIMKHRWF 311
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 147 bits (371), Expect = 7e-35
Identities = 87/278 (31%), Positives = 151/278 (54%), Gaps = 19/278 (6%)
Query: 153 NDFKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQR 209
+ F+ + LG GSY V L + ++ + YA+K+L K L + +V+ +E++ L
Sbjct: 57 SQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRS-KMERDILAE 115
Query: 210 LKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGF 269
+ N I+ L++ FQ E LY +L++ GDL + + K E+ ++Y A++ AL
Sbjct: 116 V-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH 174
Query: 270 MHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
+H G+I+RDLKPENILLD + +K+TDFG S++ + +D R+ SF GT EY
Sbjct: 175 LHSLGIIYRDLKPENILLDEEGHIKITDFG-------LSKEAIDHD--KRAYSFCGTIEY 225
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
++PE++N D W+FG ++F+M+ G PF+ + T ++K +
Sbjct: 226 MAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGE 285
Query: 390 VRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+ L++ + +NP RL + +IK H FF +++
Sbjct: 286 AQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDW 323
Score = 100 bits (248), Expect = 1e-20
Identities = 84/341 (24%), Positives = 160/341 (46%), Gaps = 35/341 (10%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ E +G GSYS ++ +YAVKI++K ++++ L R
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI-------LLRYGQHP 467
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
II+L + D +Y ++E G+LL + + +E+ I + ++H +G
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQG 527
Query: 275 VIHRDLKPENILLDVDM----KVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
V+HRDLKP NIL + +++ DFG A+ L + + L + + TA +V
Sbjct: 528 VVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNG-------LLMTPCY--TANFV 578
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQFAFTAGF 386
+PE+L D CDIW+ G +L+ M+AG PF AN T ++++ ++A + G
Sbjct: 579 APEVLKRQGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGN 637
Query: 387 PMTVRDLVKNILIK----NPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSA 442
++ D K+++ K +P +RL Q+ H + + + + + + L K +
Sbjct: 638 WDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHL--VKGAM 695
Query: 443 RALQSSVPKVASSPAINPIHEPVRQSSVSPKITPKNTTTAQ 483
A ++ + +P + EPV S+++ + K T+ +
Sbjct: 696 AATYFALNRTPQAPRL----EPVLSSNLAQRRGMKRLTSTR 732
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 147 bits (370), Expect = 1e-34
Identities = 86/316 (27%), Positives = 169/316 (53%), Gaps = 17/316 (5%)
Query: 112 ISESMQRRQKEWAD-RGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVL 170
+++ ++++++E D R + ++ + K + +N+F++ + LG G++ V+
Sbjct: 106 VADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVI 165
Query: 171 LATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLY 230
L + + YA+KIL KE ++ + +V + E LQ ++ + +L ++FQ L
Sbjct: 166 LVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPF-LTALKYSFQTHDRLC 224
Query: 231 FLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH-DKGVIHRDLKPENILLDV 289
F++EYA G+L + + +E ++Y A+I+ AL ++H +K V++RDLK EN++LD
Sbjct: 225 FVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDK 284
Query: 290 DMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAF 349
D +K+TDFG + + +K ++ F GT EY++PE+L DN D W
Sbjct: 285 DGHIKITDFGLCK-------EGIKDGATMKT--FCGTPEYLAPEVLEDNDYGRAVDWWGL 335
Query: 350 GCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRL--- 406
G ++++M+ G+ PF + F+ ++ + F + L+ +L K+P++RL
Sbjct: 336 GVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGG 395
Query: 407 --LINQIKAHQFFADV 420
+I H+FFA +
Sbjct: 396 SEDAKEIMQHRFFAGI 411
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 147 bits (370), Expect = 1e-34
Identities = 82/287 (28%), Positives = 157/287 (54%), Gaps = 15/287 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF F + LG G++ V+L S+K YA+KI+ KE ++ + +V + E L
Sbjct: 177 MDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACV 236
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ + L ++FQ + + F++E+A G+L + +++ + +E T++Y ++II ALG++H
Sbjct: 237 HPF-LTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLH 295
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+ +++RD+K EN+LLD D +K+TDFG + +++KY ++++F GT EY++
Sbjct: 296 HRNIVYRDMKLENLLLDRDGHIKITDFGLCK-------EEIKYG--DKTSTFCGTPEYLA 346
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ D D D W G ++++M+ G+ PF A F+ + F
Sbjct: 347 PEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAV 406
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPP 433
L+ +L + P +RL ++ +FF DV++ + +PP
Sbjct: 407 TLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPP 453
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 147 bits (370), Expect = 1e-34
Identities = 82/287 (28%), Positives = 157/287 (54%), Gaps = 15/287 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF F + LG G++ V+L S+K YA+KI+ KE ++ + +V + E L
Sbjct: 177 MDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLTENRVLYACV 236
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ + L ++FQ + + F++E+A G+L + +++ + +E T++Y ++II ALG++H
Sbjct: 237 HPF-LTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLH 295
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+ +++RD+K EN+LLD D +K+TDFG + +++KY ++++F GT EY++
Sbjct: 296 HRNIVYRDMKLENLLLDRDGHIKITDFGLCK-------EEIKYG--DKTSTFCGTPEYLA 346
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++ D D D W G ++++M+ G+ PF A F+ + F
Sbjct: 347 PEVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAV 406
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPP 433
L+ +L + P +RL ++ +FF DV++ + +PP
Sbjct: 407 TLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPP 453
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 147 bits (370), Expect = 1e-34
Identities = 81/264 (30%), Positives = 145/264 (54%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG G+++ V A +I++ + A+K+++K+ + K + + E + + RL
Sbjct: 12 YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVM-RLVRHP 70
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
++ L+ ++ +YF +EY G+L + K G + E + Y Q+I A+ + H +G
Sbjct: 71 HVVFLHEVMASKTKIYFAMEYVKGGELFDKVSK-GKLKENIARKYFQQLIGAIDYCHSRG 129
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+LLD + +K++DFG + L +S +D L + + GT YV+PE+
Sbjct: 130 VYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLH-------TTCGTPAYVAPEV 182
Query: 335 L-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+ Y + D+W+ G +L+ ++AG PF N ++K+ K +F FP V+ L
Sbjct: 183 IGKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKL 242
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+ IL NP R+ I +I + +F
Sbjct: 243 LSRILDPNPNSRIKIEKIMENSWF 266
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 146 bits (369), Expect = 1e-34
Identities = 83/278 (29%), Positives = 153/278 (54%), Gaps = 19/278 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I++ K TLG G++ V L + + A+KI+ K ++KQ ++++V EKN + + +
Sbjct: 691 ISELKKIATLGCGAFGRVDLVAY--NQQALALKIIKKIEVVKQDQIEHVYNEKNVMIKCR 748
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ LY T++++ +YFL+E GD+ ++M K +EK ++ A +++A ++H
Sbjct: 749 QSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLH 808
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
I+RDLKPEN++L D KL DFG A+ + ++N+F GT EYV+
Sbjct: 809 SHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNE----------KTNTFAGTPEYVA 858
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK--VQFAFTAGFPMT 389
PE++ D D D WA G ++++++ GK PF+ N+ +Q+++ + P +
Sbjct: 859 PEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPSRIPKS 918
Query: 390 VRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+ LV+++ + P RL I IK H +F +++
Sbjct: 919 AQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDW 956
>SPAC821.12 [R] KOG0605 NDR and related serine/threonine kinases
Length = 469
Score = 145 bits (367), Expect = 2e-34
Identities = 89/311 (28%), Positives = 160/311 (50%), Gaps = 43/311 (13%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DF + +G G++ V L +++ K YA+K L K + K+ ++ +V E++ L
Sbjct: 90 LEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVE-S 148
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
++ ++SLY+ FQD LY ++E+ P GDL++++ + + +E T++Y A+ + A+ +H
Sbjct: 149 DSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVH 208
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFG-----------------------------TAR 302
G IHRD+KP+NIL+D D +KL+DFG A
Sbjct: 209 RMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAI 268
Query: 303 LLDSTSEDDL---KYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAG 359
L +S+D + K + + S VGT +Y++PE+ CD W+ G I+F+ + G
Sbjct: 269 WLTMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIG 328
Query: 360 KPPFKANNEYLTFQKVMKVQFAFTAGFP------MTVRDLVKNILIKNPER--RLLINQI 411
PPF + N + T++K+ + + T FP + RDL+ ++ + R R +I
Sbjct: 329 WPPFCSENSHETYRKI--INWRETLTFPNDIHLSIEARDLMDRLMTDSEHRLGRGGAIEI 386
Query: 412 KAHQFFADVNF 422
H FF +++
Sbjct: 387 MQHPFFTGIDW 397
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 145 bits (367), Expect = 2e-34
Identities = 83/264 (31%), Positives = 142/264 (53%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG G+++ V A +I++ K A+K++ KE ++K V + E + ++ +K+
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPN 83
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ +S +YF +E G+L + + K G + E + Y Q+I A+ F H +G
Sbjct: 84 -IVELHEVMASKSKIYFAMELVRGGELFAKVAK-GRLREDVARVYFQQLISAVDFCHSRG 141
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE- 333
V HRDLKPEN+LLD + +K+TDFG + + +D L + + GT YV+PE
Sbjct: 142 VYHRDLKPENLLLDEEGNLKVTDFGLSAFTEHLKQDGLLH-------TTCGTPAYVAPEV 194
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+L Y + D+W+ G ILF ++AG PF+ +N ++K+ + F R L
Sbjct: 195 ILKKGYDGAKADLWSCGVILFVLLAGYLPFQDDNLVNMYRKIYRGDFKCPGWLSSDARRL 254
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
V +L NP R+ I ++ +F
Sbjct: 255 VTKLLDPNPNTRITIEKVMDSPWF 278
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 145 bits (366), Expect = 3e-34
Identities = 87/320 (27%), Positives = 167/320 (52%), Gaps = 17/320 (5%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
K +++F + LG G++ V+L+ S +++ A+K+L K+ +I+ ++ EK
Sbjct: 818 KVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFL 877
Query: 209 RLKNTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDA 266
TK + +LY +FQ E+ +YF +E+ GDL+ ++ ++ + ++YAA+++ A
Sbjct: 878 LATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYAAEVLLA 936
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
L + HD GVI+RDLK ENILL + +K+ D+G + D++ Y R+++F GT
Sbjct: 937 LKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK-------DEMWYG--NRTSTFCGT 987
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
E+++PE+L + D WAFG +L+QM+ + PF ++E F ++ + +
Sbjct: 988 PEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDM 1047
Query: 387 PMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVS 441
+ + + +L K+PE+RL +++ FF ++NF + PP + K
Sbjct: 1048 AGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSP 1107
Query: 442 ARALQSSVPKVASSPAINPI 461
++ P + P+
Sbjct: 1108 EDTSYFEQEFTSAPPTLTPL 1127
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 145 bits (366), Expect = 3e-34
Identities = 104/381 (27%), Positives = 179/381 (46%), Gaps = 22/381 (5%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
I + I DFK G LG GS++ V A SI S + A+K+++K+ + K V+ V E
Sbjct: 5 IGEKIEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIH 64
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS-VNEKCTQYYAAQIIDA 266
+LK+ I+ LY F+D + +Y +LE NG++ ++ +E +++ QII
Sbjct: 65 CQLKHPS-ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITG 123
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
+ ++H G++HRDL N+LL +M +K+ DFG A L E + + GT
Sbjct: 124 MLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHE---------KHYTLCGT 174
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
Y+SPE+ + D+W+ GC+ + ++ G+PPF + T KV+ +
Sbjct: 175 PNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFL 234
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQ 446
+ +DL+ +L +NP RL ++ + H F + N S KD + S A
Sbjct: 235 SIEAKDLIHQLLRRNPADRLSLSSVLDHPFMS----RNSSTKSKDLGTVEDSIDSGHATI 290
Query: 447 SSVPKVASSPAINPIHEPVRQSSVSP------KITPKN-TTTAQRPNGDTTSTTTKRELD 499
S+ +SS +I+ R+ + + PKN ++T +GD S T+
Sbjct: 291 STAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQ 350
Query: 500 PRTQRILNNVKKEISQRNHRR 520
+ V ++ +R H R
Sbjct: 351 ETSNSGRGRVIQDAEERPHSR 371
>Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 277
Score = 145 bits (366), Expect = 3e-34
Identities = 76/223 (34%), Positives = 134/223 (60%), Gaps = 13/223 (5%)
Query: 160 TLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISL 219
T+G G++ V L + +A+K+++ +I++K+ ++V+ EK+ L+ + + +I L
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPF-LIRL 112
Query: 220 YFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRD 279
++T+ +E LY L+EY P G+L S +R G + +Y+A+II A+ ++H K +++RD
Sbjct: 113 FWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEIICAIEYLHSKEIVYRD 172
Query: 280 LKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNY 339
LKPENILLD D +KLTDFG A+ L+ R+ + GT EY++PE++
Sbjct: 173 LKPENILLDRDGHIKLTDFGFAK------------KLVDRTWTLCGTPEYLAPEVIQSKG 220
Query: 340 VDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF 382
D WA G ++F+M++G PPF +N + +QK++ + F
Sbjct: 221 HGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYF 263
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 145 bits (366), Expect = 3e-34
Identities = 83/264 (31%), Positives = 144/264 (54%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG G+++ V S +N+ A+K+++K+ +++ + + E + + R+
Sbjct: 12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVM-RIAKHP 70
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
++ LY +S +YF++EY G+L + + K G + E Y Q+I A+ F H +G
Sbjct: 71 NVVELYEVMATKSRIYFVIEYCKGGELFNKVAK-GKLKEDVAWKYFYQLISAVDFCHSRG 129
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRD+KPEN+LLD + +K++DFG + L D +D L + + GT YV+PE+
Sbjct: 130 VYHRDIKPENLLLDDNDNLKVSDFGLSALADCKRQDGLLH-------TTCGTPAYVAPEV 182
Query: 335 LN-DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+N Y + DIW+ G +LF ++AG PF N ++K+ K F + F V+ L
Sbjct: 183 INRKGYEGTKADIWSCGVVLFVLLAGYLPFHDTNLMEMYRKIGKADFKCPSWFAPEVKRL 242
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+ +L N E R+ I +IK +F
Sbjct: 243 LCKMLDPNHETRITIAKIKESSWF 266
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 144 bits (363), Expect = 6e-34
Identities = 103/381 (27%), Positives = 179/381 (46%), Gaps = 22/381 (5%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
I + I DFK G LG GS++ V A SI + + A+K+++K+ + K V+ V E
Sbjct: 5 IGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIH 64
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS-VNEKCTQYYAAQIIDA 266
+LK+ I+ LY F+D + +Y +LE NG++ ++ +E +++ QII
Sbjct: 65 CQLKHPS-ILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITG 123
Query: 267 LGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
+ ++H G++HRDL N+LL +M +K+ DFG A L E + + GT
Sbjct: 124 MLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHE---------KHYTLCGT 174
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
Y+SPE+ + D+W+ GC+ + ++ G+PPF + T KV+ +
Sbjct: 175 PNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFL 234
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQ 446
+ +DL+ +L +NP RL ++ + H F + N S KD + S A
Sbjct: 235 SIEAKDLIHQLLRRNPADRLSLSSVLDHPFMS----RNSSTKSKDLGTVEDSIDSGHATI 290
Query: 447 SSVPKVASSPAINPIHEPVRQSSVSP------KITPKN-TTTAQRPNGDTTSTTTKRELD 499
S+ +SS +I+ R+ + + PKN ++T +GD S T+
Sbjct: 291 STAITASSSTSISGSLFDKRRLLIGQPLPNKMTVFPKNKSSTDFSSSGDGNSFYTQWGNQ 350
Query: 500 PRTQRILNNVKKEISQRNHRR 520
+ V ++ +R H R
Sbjct: 351 ETSNSGRGRVIQDAEERPHSR 371
>At2g19400 [R] KOG0605 NDR and related serine/threonine kinases
Length = 545
Score = 144 bits (362), Expect = 8e-34
Identities = 95/365 (26%), Positives = 176/365 (48%), Gaps = 60/365 (16%)
Query: 117 QRRQKEW-----------ADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGS 165
QR+++ W +++ +++D+ K+T + ++DF +G G+
Sbjct: 56 QRKERRWVLEQKIASLDVSEKEQLELLEDLQRKETEYTRLMRNRLCVDDFDLLSIIGRGA 115
Query: 166 YSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQD 225
+ V L ++ YA+K L K ++ + +V++V E+N L + + I+ LY++FQD
Sbjct: 116 FGEVRLCREKKTGNIYAMKKLKKSEMLSRGQVEHVRAERNLLAEVASDC-IVKLYYSFQD 174
Query: 226 ESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENI 285
LY ++EY GD+++L+ + ++ E ++Y AQ + A+ +H +HRD+KP+N+
Sbjct: 175 PEYLYLIMEYLSGGDVMTLLMREETLTETVARFYIAQSVLAIESIHKHNYVHRDIKPDNL 234
Query: 286 LLDVDMKVKLTDFGTARLLD-------------------------------------STS 308
LLD +KL+DFG + LD +
Sbjct: 235 LLDKYGHMKLSDFGLCKPLDCRNISAMNVNEPLNDENINESIDGDENCSIGRRGRRWKSP 294
Query: 309 EDDLKYDLLTR---SNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKA 365
+ L++ + R + S VGT +Y++PE+L CD W+ G I+++M+ G PPF +
Sbjct: 295 LEQLQHWQINRRKLAYSTVGTPDYIAPEVLLKKGYGVECDWWSLGAIMYEMLVGYPPFYS 354
Query: 366 NNEYLTFQKVM--KVQFAFTAGFPMT--VRDLVKNILIKNPER----RLLINQIKAHQFF 417
++ T +K++ + F G +T RDL+ +L + R QIKAH +F
Sbjct: 355 DDPVTTCRKIVSWRTHLVFPEGARLTPEARDLICRLLCDSEHRLGSHGAGAEQIKAHTWF 414
Query: 418 ADVNF 422
DV +
Sbjct: 415 KDVEW 419
>YGR092w [R] KOG0605 NDR and related serine/threonine kinases
Length = 572
Score = 142 bits (359), Expect = 2e-33
Identities = 91/319 (28%), Positives = 148/319 (45%), Gaps = 40/319 (12%)
Query: 143 ITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI 202
+ K+ +K DF+ +G G Y V LA ++ + A+KILNK+ L K + K+V
Sbjct: 165 LRKRRLKPKNRDFEMITQVGQGGYGQVYLARKKDTKEVCALKILNKKLLFKLNETKHVLT 224
Query: 203 EKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQ 262
E++ L ++ + ++ L + FQD SLY +E+ P GD +L+ + ++Y ++
Sbjct: 225 ERDILTTTRS-EWLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARFYISE 283
Query: 263 IIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSE-----------DD 311
+ A+ +HD G HRDLKPEN L+D +KLTDFG A S D
Sbjct: 284 MFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAAGTISNERIESMKIRLEKIKD 343
Query: 312 LKYDLLTR--------------------SNSFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
L++ T +NS VG+ +Y++ E+L DF D W+ GC
Sbjct: 344 LEFPAFTEKSIEDRRKMYNQLREKEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGC 403
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMK--------VQFAFTAGFPMTVRDLVKNILIKNPE 403
+LF+ + G PF ++ T+ + + Q A F DL+ ++
Sbjct: 404 MLFESLVGYTPFSGSSTNETYDNLRRWKQTLRRPRQSDGRAAFSDRTWDLITRLIADPIN 463
Query: 404 RRLLINQIKAHQFFADVNF 422
R +K +FAD+NF
Sbjct: 464 RLRSFEHVKRMSYFADINF 482
>YNL161w [R] KOG0605 NDR and related serine/threonine kinases
Length = 756
Score = 142 bits (358), Expect = 2e-33
Identities = 104/428 (24%), Positives = 186/428 (43%), Gaps = 89/428 (20%)
Query: 62 PPVLTKALTD--------VDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPIS 113
P +LTK D ++NF KY RN+ +ET
Sbjct: 272 PDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELET------------------ 313
Query: 114 ESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLAT 173
+ W++ + + + K++ + + + + DF + +G G++ V L
Sbjct: 314 ---ELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQ 370
Query: 174 SIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLL 233
++ K YA+K L K + K+ ++ +V E++ L ++ ++SLY++FQD LY ++
Sbjct: 371 KKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAG-SDSPWVVSLYYSFQDAQYLYLIM 429
Query: 234 EYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKV 293
E+ P GDL++++ + E T++Y A+ I A+ +H G IHRD+KP+NIL+D+ +
Sbjct: 430 EFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHI 489
Query: 294 KLTDFGTARLLDSTSEDDLKYDL------------------------------------L 317
KL+DFG + T + + L L
Sbjct: 490 KLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISL 549
Query: 318 TRSN----------------SFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKP 361
T SN S VGT +Y++PE+ CD W+ G I+++ + G P
Sbjct: 550 TMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWP 609
Query: 362 PFKANNEYLTFQKVMK----VQFAFTAGFPMTVRDLVKNILIKNPE---RRLLINQIKAH 414
PF + T++K+M +QF DL++ +L + R ++IK+H
Sbjct: 610 PFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSH 669
Query: 415 QFFADVNF 422
FF V++
Sbjct: 670 PFFRGVDW 677
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 142 bits (358), Expect = 2e-33
Identities = 84/267 (31%), Positives = 143/267 (53%), Gaps = 11/267 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ ++ G T+G+G+++ V A + ++ A+KI+ K ++K + V + E + ++ ++
Sbjct: 8 VGKYEVGRTIGEGTFAKVKFARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVR 67
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ LY S +Y +LE+ G+L + G + E ++ Y Q++DA+ H
Sbjct: 68 HPN-IVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCH 126
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
KGV HRDLKPEN+LLD + +K++DFG + L E L R+ GT YV+
Sbjct: 127 CKGVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVE-------LLRTT--CGTPNYVA 177
Query: 332 PELLN-DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE+L+ Y DIW+ G ILF ++AG PF + ++K+ +F+ F V
Sbjct: 178 PEVLSGQGYDGSAADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEV 237
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
+ L+ IL NP+ R+ I IK +F
Sbjct: 238 KFLIHRILDPNPKTRIQIQGIKKDPWF 264
>CE19898 [T] KOG0614 cGMP-dependent protein kinase
Length = 737
Score = 142 bits (357), Expect = 3e-33
Identities = 91/314 (28%), Positives = 166/314 (51%), Gaps = 23/314 (7%)
Query: 116 MQRRQKEWADRGA-AMIVKDVPD--KQTGKITKQVIKKGINDFKFGETLGDGSYSTV-LL 171
++ +K++ D+ A +V++ P K ++ + + + K TLG G + V L+
Sbjct: 384 LESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELV 443
Query: 172 ATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYF 231
+ + K +A+K L K++++ ++ +++ E+N + +T I+ LY TF+D+ +Y
Sbjct: 444 CVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMET-STDWIVKLYKTFRDQKFVYM 502
Query: 232 LLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDM 291
LLE G+L + +R G ++ ++Y A +++ L ++H K +++RDLKPEN LL
Sbjct: 503 LLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTG 562
Query: 292 KVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
+KL DFG A+ L S ++ +F GT EYVSPE++ + D D WA G
Sbjct: 563 YLKLVDFGFAKKLASG----------RKTWTFCGTPEYVSPEIILNKGHDQAADYWALGI 612
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMKVQFAF---TAGFPMTVRDLVKNILIKNPERRL-- 406
+ +++ G+PPF+A++ T+ ++K A T LVK + NP RL
Sbjct: 613 YICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGS 672
Query: 407 ---LINQIKAHQFF 417
+N I+ H++F
Sbjct: 673 GSGGVNDIRKHRWF 686
>CE19897 [T] KOG0614 cGMP-dependent protein kinase
Length = 780
Score = 142 bits (357), Expect = 3e-33
Identities = 91/314 (28%), Positives = 166/314 (51%), Gaps = 23/314 (7%)
Query: 116 MQRRQKEWADRGA-AMIVKDVPD--KQTGKITKQVIKKGINDFKFGETLGDGSYSTV-LL 171
++ +K++ D+ A +V++ P K ++ + + + K TLG G + V L+
Sbjct: 427 LESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELV 486
Query: 172 ATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYF 231
+ + K +A+K L K++++ ++ +++ E+N + +T I+ LY TF+D+ +Y
Sbjct: 487 CVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMET-STDWIVKLYKTFRDQKFVYM 545
Query: 232 LLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDM 291
LLE G+L + +R G ++ ++Y A +++ L ++H K +++RDLKPEN LL
Sbjct: 546 LLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTG 605
Query: 292 KVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
+KL DFG A+ L S ++ +F GT EYVSPE++ + D D WA G
Sbjct: 606 YLKLVDFGFAKKLASG----------RKTWTFCGTPEYVSPEIILNKGHDQAADYWALGI 655
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMKVQFAF---TAGFPMTVRDLVKNILIKNPERRL-- 406
+ +++ G+PPF+A++ T+ ++K A T LVK + NP RL
Sbjct: 656 YICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGS 715
Query: 407 ---LINQIKAHQFF 417
+N I+ H++F
Sbjct: 716 GSGGVNDIRKHRWF 729
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 141 bits (356), Expect = 4e-33
Identities = 82/276 (29%), Positives = 148/276 (52%), Gaps = 19/276 (6%)
Query: 155 FKFGETLGDGSYSTVLLATSI---ESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
F+ + LG GS+ V L + +S YA+K+L K L + +V+ +E++ L +
Sbjct: 62 FELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVR-TKMERDILADV- 119
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N ++ L++ FQ E LY +L++ GDL + + K E+ ++Y A++ L +H
Sbjct: 120 NHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLH 179
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
G+I+RDLKPENILLD + +KLTDFG S++ + ++ ++ SF GT EY++
Sbjct: 180 SLGIIYRDLKPENILLDEEGHIKLTDFG-------LSKEAIDHE--KKAYSFCGTVEYMA 230
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE++N D W++G ++F+M+ G PF+ + T ++K + +
Sbjct: 231 PEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQ 290
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
L++ + +NP RL +IK H F++ +++
Sbjct: 291 SLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDW 326
Score = 105 bits (263), Expect = 2e-22
Identities = 93/322 (28%), Positives = 150/322 (45%), Gaps = 37/322 (11%)
Query: 159 ETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIIS 218
ET+G GSYS +N +YAVK+++K ++++ L R II+
Sbjct: 422 ETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI-------LLRYGQHPNIIT 474
Query: 219 LYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHR 278
L + D +Y + E G+LL + + +E+ + I + ++H +GV+HR
Sbjct: 475 LKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHR 534
Query: 279 DLKPENILLDVDMK-----VKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
DLKP NIL VD +++ DFG A+ L +E+ L L+T TA +V+PE
Sbjct: 535 DLKPSNILY-VDESGNPECLRICDFGFAKQL--RAENGL---LMTPCY----TANFVAPE 584
Query: 334 LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM----KVQFAFTAG---- 385
+L D CDIW+ G +L+ M+AG PF AN T ++++ +F + G
Sbjct: 585 VLKRQGYDEGCDIWSLGILLYTMLAGYTPF-ANGPSDTPEEILTRIGSGKFTLSGGNWNT 643
Query: 386 FPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPEL--GPYKVSAR 443
T +DLV +L +P +RL Q+ H + + S +L G +
Sbjct: 644 VSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYS 703
Query: 444 ALQSSVPKVASSPAINPIHEPV 465
AL SS P +P + PI +
Sbjct: 704 ALNSSKP----TPQLKPIESSI 721
>CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 879
Score = 141 bits (356), Expect = 4e-33
Identities = 79/284 (27%), Positives = 147/284 (50%), Gaps = 14/284 (4%)
Query: 154 DFKFGETLGDGSYSTVLLA---TSIESNKKYAVKILNKEYLI-KQKKVKYVNIEKNTLQR 209
DF+ + +G+G Y V T + YA+K++ K + +K +++ E+ L+
Sbjct: 22 DFERLKLVGEGGYGKVFQVRKQTGEDKGTIYAMKVITKRKVTGTEKDLRHARDERKILET 81
Query: 210 LKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGF 269
+ N+ + L++ FQ LY +LE+ G+L +L+ + E+ ++Y ++II A+
Sbjct: 82 I-NSPFLCDLHYAFQTNEKLYLVLEFLHGGELYTLLERKSDWPEEYARFYLSEIILAIEH 140
Query: 270 MHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
+H +++RDLKP+N++L++ V LTDFG + E L +F GT EY
Sbjct: 141 LHGHDIVYRDLKPDNVMLNLAGHVVLTDFGLCKYKLKKGEKTL---------TFCGTHEY 191
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
++PE++ D D+WA G +++ M G PPF + ++K + +
Sbjct: 192 MAPEMIRKVGHDHAVDVWALGILMYDMFMGGPPFTGETPADKDKSILKGKVRLPPKLSAS 251
Query: 390 VRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPP 433
+DL+K I+ ++P R+ I IK H+FF ++++ D +PP
Sbjct: 252 GKDLIKRIIKRDPTLRITIPDIKEHEFFEEIDWDKLMAHDFEPP 295
>CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1370
Score = 140 bits (354), Expect = 7e-33
Identities = 87/284 (30%), Positives = 148/284 (51%), Gaps = 15/284 (5%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF + +G+Y V L E+ +++A+K +NK+ L+ + +V V E++ L N
Sbjct: 356 DDFDTIRLVSNGAYGAVYLVRHRETRQRFALKKMNKQTLMLRNQVDQVFAERDILTMADN 415
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
++S Y +F+ L L+EY GD +L++ G++ + + Y A+ I A+ ++H
Sbjct: 416 PF-VVSFYGSFETRQYLCMLMEYVEGGDCAALLKSAGTLPVELVRLYVAETILAIEYLHS 474
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTAR--LLDSTSEDDLKYDLLTRSNSF-----VG 325
G++HRDLKP+N+L+ +KLTDFG ++ L++ T+ YD + + F G
Sbjct: 475 YGIVHRDLKPDNLLITAMGHIKLTDFGLSKIGLMNRTTLVAEGYDAVVETQQFQDKQLCG 534
Query: 326 TAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF--- 382
T EY++PE++ D WA G IL++ + G PF F KV+ +
Sbjct: 535 TPEYIAPEVILRRGYGKPVDWWALGIILYEFLVGIVPFFGETPEALFSKVISEDVEYPEE 594
Query: 383 TAGFPMTVRDLVKNILIKNPERRL-LIN---QIKAHQFFADVNF 422
P DL + +L KNP RL +N Q+ AH+FF ++F
Sbjct: 595 DEALPPEAADLCRRLLEKNPAERLGTLNGAAQLMAHEFFILLDF 638
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 140 bits (353), Expect = 9e-33
Identities = 114/466 (24%), Positives = 227/466 (48%), Gaps = 39/466 (8%)
Query: 10 PIIPTSGSARSVMHRPTPPPIPMELSHPPLPTIRTTDDLSNLS-EMKPFGKPNPPVLTKA 68
P + SG+ PT P+ +++ P L + ++ L +++P P PP +
Sbjct: 526 PTVNHSGTFSPQAPVPTTVPV-VDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPP-RASS 583
Query: 69 LTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPISESMQRRQKEWADRGA 128
L ++D L + ++ ET+ ++D SI LP S+S + +
Sbjct: 584 LGEIDESSELRVLDIPGQDS-----ETVFDIQNDRNSI---LPKSQSEYKPDTPQSGLEY 635
Query: 129 AMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNK 188
+ I +++ D+++ +Q + + DF+ LG G + VLLA +N+ +A+K L K
Sbjct: 636 SGI-QELEDRRS----QQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKK 690
Query: 189 EYLIKQKKVKYVNIEKNTLQRLKNTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMR 246
++ + +V + EK + + + + +++L+ FQ + + F++EYA GDL+ M
Sbjct: 691 GDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLM--MH 748
Query: 247 KHGSV-NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLD 305
H V +E +YAA ++ L ++H+ +++RDLK +N+LLD + VK+ DFG +
Sbjct: 749 IHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCK--- 805
Query: 306 STSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKA 365
+ + Y R+++F GT E+++PE+L + D W G ++++M+ G+ PF
Sbjct: 806 ----EGMGYG--DRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPG 859
Query: 366 NNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQ-----IKAHQFFADV 420
++E F ++ + + +++ +L +NPERRL ++ +K H FF +
Sbjct: 860 DDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLI 919
Query: 421 NFGNGSVWDK--DPPELGPYKVSARALQSSVPKVASSPAINPIHEP 464
++ ++ DK PP + + + +P + P EP
Sbjct: 920 DW--SALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREP 963
>Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 496
Score = 140 bits (353), Expect = 9e-33
Identities = 90/286 (31%), Positives = 156/286 (54%), Gaps = 26/286 (9%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF+ + +G G++ V + ++K +A+KILNK ++K+ + E++ L N
Sbjct: 76 DFEILKVIGRGAFGEVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDN- 134
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRK-HGSVNEKCTQYYAAQIIDALGFMHD 272
K I +L++ FQD+++LY +++Y GDLL+L+ K + E ++Y A+++ A+ +H
Sbjct: 135 KWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQ 194
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
+HRD+KP+NIL+D++ ++L DFG+ L D +S+ VGT +Y+SP
Sbjct: 195 LHYVHRDIKPDNILMDMNGHIRLADFGSCL--------KLMEDGTVQSSVAVGTPDYISP 246
Query: 333 ELL-----NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
E+L CD W+ G +++M+ G+ PF A + T+ K+M + F FP
Sbjct: 247 EILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQ--FP 304
Query: 388 MTVRDLVKNI------LIKNPERRLLINQI---KAHQFFADVNFGN 424
V D+ +N LI + E RL N I K H FF+ +++ N
Sbjct: 305 AQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKHPFFSGIDWDN 350
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 140 bits (353), Expect = 9e-33
Identities = 94/334 (28%), Positives = 169/334 (50%), Gaps = 28/334 (8%)
Query: 107 PKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGI---NDFKFGETLGD 163
P S S Q++Q++ + + ++ +TG+ KQ G+ ++F+ LG
Sbjct: 212 PSSSTTSNSNQQQQQQRRNVARGLQYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGR 271
Query: 164 GSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKG--IISLYF 221
G + V+L+ +N+ YA+K L K +I + +V+ + EK + + +++LY
Sbjct: 272 GHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYS 331
Query: 222 TFQDESSLYFLLEYAPNGDLLSLMRKHGSVN-EKCTQYYAAQIIDALGFMHDKGVIHRDL 280
FQ E + F++EYA GDL+ M H V E +YAA ++ L ++H+ +I+RDL
Sbjct: 332 CFQTEQHVCFVMEYAAGGDLM--MHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDL 389
Query: 281 KPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYV 340
K +N+LLD + VK+ DFG + + D R+ +F GT E+++PE+L +
Sbjct: 390 KLDNLLLDTEGYVKIADFGLCK--EGMGFGD-------RTGTFCGTPEFLAPEVLTETSY 440
Query: 341 DFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIK 400
D W G ++F+M+ G+ PF ++E F ++ + + + +++ +L K
Sbjct: 441 TRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRK 500
Query: 401 NPERRLLINQ-----IKAHQFFADVNFGNGSVWD 429
NPERRL ++ +K FF + VWD
Sbjct: 501 NPERRLGSSERDAEDVKKQAFFRSI------VWD 528
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 140 bits (353), Expect = 9e-33
Identities = 94/334 (28%), Positives = 169/334 (50%), Gaps = 28/334 (8%)
Query: 107 PKELPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGI---NDFKFGETLGD 163
P S S Q++Q++ + + ++ +TG+ KQ G+ ++F+ LG
Sbjct: 906 PSSSTTSNSNQQQQQQRRNVARGLQYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGR 965
Query: 164 GSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKG--IISLYF 221
G + V+L+ +N+ YA+K L K +I + +V+ + EK + + +++LY
Sbjct: 966 GHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYS 1025
Query: 222 TFQDESSLYFLLEYAPNGDLLSLMRKHGSVN-EKCTQYYAAQIIDALGFMHDKGVIHRDL 280
FQ E + F++EYA GDL+ M H V E +YAA ++ L ++H+ +I+RDL
Sbjct: 1026 CFQTEQHVCFVMEYAAGGDLM--MHIHTDVFLEPRAVFYAACVVLGLQYLHENKIIYRDL 1083
Query: 281 KPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYV 340
K +N+LLD + VK+ DFG + + D R+ +F GT E+++PE+L +
Sbjct: 1084 KLDNLLLDTEGYVKIADFGLCK--EGMGFGD-------RTGTFCGTPEFLAPEVLTETSY 1134
Query: 341 DFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIK 400
D W G ++F+M+ G+ PF ++E F ++ + + + +++ +L K
Sbjct: 1135 TRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRK 1194
Query: 401 NPERRLLINQ-----IKAHQFFADVNFGNGSVWD 429
NPERRL ++ +K FF + VWD
Sbjct: 1195 NPERRLGSSERDAEDVKKQAFFRSI------VWD 1222
>Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1530
Score = 140 bits (352), Expect = 1e-32
Identities = 107/360 (29%), Positives = 182/360 (49%), Gaps = 51/360 (14%)
Query: 86 RNDSLSSVETIDSTRDDNISIPKELPISESMQRRQK------EWADRGAAMIVKDVPDKQ 139
RN+S SVET+ ++ + S S RR K EWA + +VK++ +
Sbjct: 20 RNESALSVETLL-----DVLVCLYTECSHSALRRDKYVAEFLEWA-KPFTQLVKEMQLHR 73
Query: 140 TGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKY 199
DF+ + +G G++ V + + + YA+KILNK ++K+ +
Sbjct: 74 -------------EDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETAC 120
Query: 200 VNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRK-HGSVNEKCTQY 258
E++ L + + I +L++ FQDE+ LY +++Y GDLL+L+ K + E ++
Sbjct: 121 FREERDVLVN-GDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARF 179
Query: 259 YAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLT 318
Y +++ A+ +H +HRD+KP+N+LLDV+ ++L DFG+ ++ D
Sbjct: 180 YIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMND--------DGTV 231
Query: 319 RSNSFVGTAEYVSPELL---NDNYVDF--RCDIWAFGCILFQMIAGKPPFKANNEYLTFQ 373
+S+ VGT +Y+SPE+L D + CD W+ G +++M+ G+ PF A + T+
Sbjct: 232 QSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYG 291
Query: 374 KVMKVQFAFTAGFPMTVRDLVKNI------LIKNPERRLLINQI---KAHQFFADVNFGN 424
K+M + F FP V D+ + LI + ERRL N I K H FF +N+ N
Sbjct: 292 KIMNHEERFQ--FPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWEN 349
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 139 bits (351), Expect = 2e-32
Identities = 80/264 (30%), Positives = 143/264 (53%), Gaps = 10/264 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG G++ V I + + A+KI+NK+ + ++ ++ + E + + RL
Sbjct: 15 YEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREIS-IMRLVRHP 73
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L ++ ++F++EY G+L S + K G + E + Y Q+I A+ F H +G
Sbjct: 74 NIVELKEVMATKTKIFFIMEYVKGGELFSKIVK-GKLKEDSARKYFQQLISAVDFCHSRG 132
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+L+D + +K++DFG + L + +D L + + GT YV+PE+
Sbjct: 133 VSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLH-------TQCGTPAYVAPEV 185
Query: 335 L-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
L Y + DIW+ G IL+ ++AG PF+ N ++K+ K +F + F + L
Sbjct: 186 LRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSPESKRL 245
Query: 394 VKNILIKNPERRLLINQIKAHQFF 417
+ +L+ +P +R+ I I +F
Sbjct: 246 ISKLLVVDPNKRISIPAIMRTPWF 269
>7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 393
Score = 139 bits (351), Expect = 2e-32
Identities = 86/274 (31%), Positives = 147/274 (53%), Gaps = 16/274 (5%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG+GS+ TV+L YA K+++KE L++ K+V +V+ EK+ L + +I L
Sbjct: 51 LGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAAR-FPFLIYLV 109
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
+ + LY +L G+L S R+ NEK ++YAAQ+ AL +MH +++RDL
Sbjct: 110 DSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDL 169
Query: 281 KPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYV 340
KPENILLD +K+TDFG + +D R+++ GT EY++PE++
Sbjct: 170 KPENILLDQRGYIKITDFGFTKRVDG------------RTSTLCGTPEYLAPEIVQLRPY 217
Query: 341 DFRCDIWAFGCILFQMIAGKPPFKANNE--YLTFQKVMKVQFAFTAGFPMTVRDLVKNIL 398
+ D WAFG ++++ +AG+ PF +N L + K+ + + F +R LV++++
Sbjct: 218 NKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVESLM 277
Query: 399 IKNPERRLLINQIKAHQFFADVNFGNGSVWDKDP 432
+ +R L +++ + + V G VW P
Sbjct: 278 QVDTSKRKLERRLQRRE-ESSVVPGRRLVWHSQP 310
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 139 bits (350), Expect = 2e-32
Identities = 97/299 (32%), Positives = 146/299 (48%), Gaps = 22/299 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYL------IKQKKVKYVNIEKN 205
I +K GETLG GS V LA + + AVK+++K V NIE+
Sbjct: 18 IGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIERE 77
Query: 206 -TLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQII 264
+ +L + ++SLY ++ ++LY +LEYA G+L +L+ HG + E+ QII
Sbjct: 78 IVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQII 137
Query: 265 DALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFV 324
+ + H G++HRDLKPEN+LLD +K+ DFG A L DLL S
Sbjct: 138 IGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDA-------DLLETS---C 187
Query: 325 GTAEYVSPELLND-NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYL--TFQKVMKVQFA 381
G+ Y +PE+++ Y F D+W+ G ILF ++ G+ PF N + KV K QF
Sbjct: 188 GSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFE 247
Query: 382 FTAGFPMT--VRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
++ +DL+ IL+ +P +R+ I I +H S KD P Y
Sbjct: 248 MPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTY 306
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 139 bits (350), Expect = 2e-32
Identities = 82/258 (31%), Positives = 142/258 (54%), Gaps = 10/258 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G+ +G G+++ V S + + A+K+++K+ L K + E + RL++
Sbjct: 22 YEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGNIQREIAIMHRLRHPS 81
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ +S ++F++E+A G+L + + K G E ++ Y Q+I A+G+ H +G
Sbjct: 82 -IVRLFEVLATKSKIFFVMEFAKGGELFAKVSK-GRFCEDLSRRYFQQLISAVGYCHSRG 139
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
+ HRDLKPEN+LLD + +K++DFG + L D D L + L GT YV+PE+
Sbjct: 140 IFHRDLKPENLLLDEKLDLKISDFGLSALTDQIRPDGLLHTL-------CGTPAYVAPEV 192
Query: 335 L-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
L Y + DIW+ G ILF + AG PF +N + ++K+ K +F +R L
Sbjct: 193 LAKKGYDGAKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKGEFRIPKWTSPDLRRL 252
Query: 394 VKNILIKNPERRLLINQI 411
+ +L NP+ R+ I +I
Sbjct: 253 LTRLLDTNPQTRITIEEI 270
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 139 bits (349), Expect = 3e-32
Identities = 89/298 (29%), Positives = 148/298 (48%), Gaps = 36/298 (12%)
Query: 145 KQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILN---KEYLIKQKKVKYVN 201
KQ +K + D++F ET+G GS V LA +N+ AVKI+N K +L K++ +
Sbjct: 110 KQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFLHKEQMLPPPK 169
Query: 202 IEKNTLQRLKNTKGIISLYFTFQDESSL----------------------YFLLEYAPNG 239
E++ L+R K + IS E+SL Y L EY G
Sbjct: 170 NEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGG 229
Query: 240 DLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFG 299
LL + +HGS+ E + +A I AL ++H ++HRDLK ENI++ ++K+ DFG
Sbjct: 230 QLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEIKIIDFG 289
Query: 300 TARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDN-YVDFRCDIWAFGCILFQMIA 358
+ + DS + ++F G+ + +PELL N Y D+W+FG +LF ++
Sbjct: 290 LSNIYDSRKQ----------LHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFVLVC 339
Query: 359 GKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQF 416
GK PF N + +K+ + + + + V L+ +L+ +P+RR + Q+ H +
Sbjct: 340 GKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPKRRATLKQVVEHHW 397
>Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 623
Score = 139 bits (349), Expect = 3e-32
Identities = 93/297 (31%), Positives = 155/297 (51%), Gaps = 28/297 (9%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF+ + +G G++S V + ++ + YA+KI+NK ++K+ +V E++ L +
Sbjct: 69 DDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVN-GD 127
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS-VNEKCTQYYAAQIIDALGFMH 271
+ I L+F FQDE+ LY ++EY GDLL+L+ K G + + ++Y A+I+ A+ +H
Sbjct: 128 RRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVH 187
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
G +HRD+KP+NILLD ++L DFG+ L+ D RS VGT +Y+S
Sbjct: 188 RLGYVHRDIKPDNILLDRCGHIRLADFGSCL--------KLRADGTVRSLVAVGTPDYLS 239
Query: 332 PELL-------NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT- 383
PE+L CD WA G ++M G+ PF A++ T+ K++ + +
Sbjct: 240 PEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSL 299
Query: 384 ----AGFPMTVRDLVKNILIKNPERRL---LINQIKAHQFFADVNFGNGSVWDKDPP 433
G P RD ++ +L PE RL + H FF +++ + D PP
Sbjct: 300 PLVDEGVPEEARDFIQRLLCP-PETRLGRGGAGDFRTHPFFFGLDW--DGLRDSVPP 353
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 139 bits (349), Expect = 3e-32
Identities = 76/258 (29%), Positives = 140/258 (53%), Gaps = 9/258 (3%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG G+++ V I + A+K++NK+ ++K+ + + ++ +L
Sbjct: 12 YEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L ++ ++F++E+ G+L + K G ++E + Y Q+I A+ + H +G
Sbjct: 72 NIVELKEVMATKTKIFFVMEFVKGGELFCKISK-GKLHEDAARRYFQQLISAVDYCHSRG 130
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V HRDLKPEN+LLD + +K++DFG + L + +D L + + GT YV+PE+
Sbjct: 131 VSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLH-------TQCGTPAYVAPEV 183
Query: 335 L-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
L Y + DIW+ G +L+ ++AG PF+ N ++K+ + F F F R L
Sbjct: 184 LKKKGYDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWFSPEARRL 243
Query: 394 VKNILIKNPERRLLINQI 411
+ +L+ +P+RR+ I I
Sbjct: 244 ISKLLVVDPDRRISIPAI 261
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 138 bits (348), Expect = 3e-32
Identities = 83/288 (28%), Positives = 147/288 (50%), Gaps = 22/288 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I +++ +T+G G+++ V LA I + K+ AVKI++K L K + + ++
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL--FREVRIMKVL 74
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N I+ L+ + E +LY ++EYA G++ + HG + EK + QI+ A+ + H
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K ++HRDLK EN+LLD DM +K+ DFG + ++ + ++F G+ Y +
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSN----------EFTFGNKLDTFCGSPPYAA 184
Query: 332 PELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PEL D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 185 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC 244
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
+L+K LI NP +R + QI ++ +N G+ + EL PY
Sbjct: 245 ENLLKKFLILNPSKRGTLEQIMKDRW---MNVGH------EDDELKPY 283
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 138 bits (348), Expect = 3e-32
Identities = 83/288 (28%), Positives = 147/288 (50%), Gaps = 22/288 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I +++ +T+G G+++ V LA I + K+ AVKI++K L K + + ++
Sbjct: 17 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL--FREVRIMKVL 74
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N I+ L+ + E +LY ++EYA G++ + HG + EK + QI+ A+ + H
Sbjct: 75 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 134
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K ++HRDLK EN+LLD DM +K+ DFG + ++ + ++F G+ Y +
Sbjct: 135 QKFIVHRDLKAENLLLDADMNIKIADFGFSN----------EFTFGNKLDTFCGSPPYAA 184
Query: 332 PELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PEL D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 185 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC 244
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
+L+K LI NP +R + QI ++ +N G+ + EL PY
Sbjct: 245 ENLLKKFLILNPSKRGTLEQIMKDRW---MNVGH------EDDELKPY 283
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 138 bits (348), Expect = 3e-32
Identities = 83/288 (28%), Positives = 147/288 (50%), Gaps = 22/288 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I +++ +T+G G+++ V LA I + K+ AVKI++K L K + + ++
Sbjct: 50 IGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKL--FREVRIMKVL 107
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
N I+ L+ + E +LY ++EYA G++ + HG + EK + QI+ A+ + H
Sbjct: 108 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCH 167
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
K ++HRDLK EN+LLD DM +K+ DFG + ++ + ++F G+ Y +
Sbjct: 168 QKFIVHRDLKAENLLLDADMNIKIADFGFSN----------EFTFGNKLDTFCGSPPYAA 217
Query: 332 PELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PEL D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 218 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC 277
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
+L+K LI NP +R + QI ++ +N G+ + EL PY
Sbjct: 278 ENLLKKFLILNPSKRGTLEQIMKDRW---MNVGH------EDDELKPY 316
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 138 bits (348), Expect = 3e-32
Identities = 80/267 (29%), Positives = 142/267 (52%), Gaps = 9/267 (3%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ ++ G LG GS++ V LA SIES++ AVKI+ K+ I+ + E + ++RL+
Sbjct: 22 LGKYELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMRRLR 81
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ ++ +S +Y ++E A G+L S + + G + E + Y Q+ AL F H
Sbjct: 82 HHPNILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRLPESTARRYFQQLASALRFSH 141
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
GV HRD+KP+N+LLD +K++DFG + L + L+ LL ++ GT Y +
Sbjct: 142 QDGVAHRDVKPQNLLLDEQGNLKVSDFGLSAL-----PEHLQNGLL---HTACGTPAYTA 193
Query: 332 PELLN-DNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE+++ Y + D W+ G ILF ++ G PF +N ++K+ + + F +
Sbjct: 194 PEVISRRGYDGAKADAWSCGVILFVLLVGDVPFDDSNIAAMYRKIHRRDYRFPSWISKQA 253
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
+ ++ +L NP R+ I + +F
Sbjct: 254 KSIIYQMLDPNPVTRMSIETVMKTNWF 280
>SPAC24B11.11c [R] KOG0605 NDR and related serine/threonine kinases
Length = 607
Score = 138 bits (347), Expect = 4e-32
Identities = 88/333 (26%), Positives = 161/333 (47%), Gaps = 40/333 (12%)
Query: 131 IVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEY 190
+VK ++ + K+ + DF+ +G G Y +V LA ++ + A+KI+NK
Sbjct: 184 LVKRYNGRERVYLRKRRTRISHGDFQTITQVGQGGYGSVWLARKRDTKEIVALKIMNKSV 243
Query: 191 LIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS 250
L K ++++V E++ L N++ ++ L + FQD S++Y +E+ P GD +L+ G
Sbjct: 244 LHKMDEIRHVLTERDILTTA-NSEWLVRLLYAFQDTSNIYLAMEFVPGGDFRTLLSNSGV 302
Query: 251 VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFG-TARLLDSTSE 309
+ + ++YA ++ A+ +H G IHRDLKPEN L+ +KLTDFG ++ ++
Sbjct: 303 LRDHHAKFYATEMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKI 362
Query: 310 DDLKYDLLTRSN---------------------------SFVGTAEYVSPELLNDNYVDF 342
+ +K L +N S VG+ +Y++PE+L +
Sbjct: 363 ESMKIRLQEVNNVVVPERSMRERRQVFRTLLSQDPVYAHSVVGSPDYMAPEVLRGENYNH 422
Query: 343 RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKN------ 396
D W+ GCI+++ ++G PPF +N T+ + + F RDL N
Sbjct: 423 SVDYWSLGCIMYECLSGFPPFSGSNVNETWSNLKNWRKCFQRPHYDDPRDLEFNWRDDAW 482
Query: 397 ----ILIKNPERRLL-INQIKAHQFFADVNFGN 424
I +P+ R + Q+ H +F+ +++ N
Sbjct: 483 DFVCHCITDPKDRFCSLKQVMQHPYFSKIDWKN 515
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 138 bits (347), Expect = 4e-32
Identities = 78/271 (28%), Positives = 141/271 (51%), Gaps = 14/271 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++DF G LG G + V ++ ++ + A+K+L K L++ + E L+
Sbjct: 41 LDDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLR 100
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS--VNEKCTQYYAAQIIDALGF 269
+ I++LY F D+ ++ +L+YA G+L ++++ VNE + Q+ +AL +
Sbjct: 101 HPN-ILTLYGYFHDDKRVFVILDYASRGELFNVLQSQPGHKVNEVIAGRFVRQLANALHY 159
Query: 270 MHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
H KGVIHRD+KPEN+LLD + +KL DFG + + D ++ ++ GT +Y
Sbjct: 160 CHSKGVIHRDIKPENLLLDSKLNLKLADFGWSVVADH-----------SKRHTLCGTMDY 208
Query: 330 VSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
++PE++++ DF DIWA G +LF+M+ G PF ++ + + +
Sbjct: 209 LAPEMVSNQPHDFNVDIWAIGILLFEMLVGYAPFANQTGDKLIARIKECKIYIPSVVTDG 268
Query: 390 VRDLVKNILIKNPERRLLINQIKAHQFFADV 420
L+ I+ K P+ RL + I AH + ++
Sbjct: 269 AASLINAIIKKEPQERLPLVDIMAHPWIKEM 299
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 138 bits (347), Expect = 4e-32
Identities = 88/321 (27%), Positives = 153/321 (47%), Gaps = 21/321 (6%)
Query: 143 ITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI 202
++ + + I D++ LG G ++TV A + +++ A+K+++K+ + V
Sbjct: 2 LSNRAFGETIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQ 61
Query: 203 EKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAA- 261
E RLK+ ++ LY FQD + +Y +LE A NG+L M + T+ AA
Sbjct: 62 EVEIHSRLKHPS-VLQLYTFFQDANYVYLVLELAHNGELHRYMNH---IARPFTETEAAS 117
Query: 262 ---QIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLT 318
Q++ L ++H ++HRD+ N+LL +M VK+ DFG A L E
Sbjct: 118 ILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDE--------- 168
Query: 319 RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKV 378
R + GT Y+SPE+++ D+W+ GC+L+ ++ G+PPF+ + T KV+
Sbjct: 169 RHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMS 228
Query: 379 QFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
++ A +DL+ +L K P R+ + + H F + G S P L +
Sbjct: 229 EYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLKCSNGGHSA----PGALNVF 284
Query: 439 KVSARALQSSVPKVASSPAIN 459
S + S + ASS + N
Sbjct: 285 SQSMESGDSGIITFASSDSRN 305
>7296166 [T] KOG0614 cGMP-dependent protein kinase
Length = 768
Score = 138 bits (347), Expect = 4e-32
Identities = 86/319 (26%), Positives = 162/319 (49%), Gaps = 24/319 (7%)
Query: 112 ISESMQRRQKEWADRGAAMIVKDVP----DKQTGKITKQVIKKGINDFKFGETLGDGSYS 167
I + + ++K++ D + +K D+ ++ ++ + D + TLG G +
Sbjct: 410 IGDLCELKEKDYGDESRKLAMKQAQESCRDEPKEQLQQEFPDLKLTDLEVVSTLGIGGFG 469
Query: 168 TVLLATSIESNKK--YAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQD 225
V L + ++ +A+K L K +++ K+ +++ E++ + ++ I LY TF+D
Sbjct: 470 RVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIMLSSRSPF-ICRLYRTFRD 528
Query: 226 ESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENI 285
E +Y LLE G++ +++R GS + Q+ ++ A ++H +G+I+RDLKPEN+
Sbjct: 529 EKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEYLHARGIIYRDLKPENL 588
Query: 286 LLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCD 345
+LD VK+ DFG A+ + ++S ++ +F GT EYV+PE++ + D D
Sbjct: 589 MLDERGYVKIVDFGFAKQIGTSS----------KTWTFCGTPEYVAPEIILNKGHDRAVD 638
Query: 346 IWAFGCILFQMIAGKPPFKANNEYLTFQKVMK--VQFAFTAGFPMTVRDLVKNILIKNPE 403
WA G ++ +++ G PPF A + T+ ++K AF L+K + P
Sbjct: 639 YWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRLCRDVPS 698
Query: 404 RRL-----LINQIKAHQFF 417
RL I IK H++F
Sbjct: 699 ERLGYQTGGIQDIKKHKWF 717
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 138 bits (347), Expect = 4e-32
Identities = 79/283 (27%), Positives = 142/283 (49%), Gaps = 17/283 (6%)
Query: 134 DVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK 193
D+PD+ ++ K+ +F G G ++ +E++ +A KI++K+ +IK
Sbjct: 11 DIPDRLVDINQRKTYKR----MRF---FGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIK 63
Query: 194 QKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNE 253
+ K ++ T+ R N I+ + F+D ++Y +LE ++ L ++ S+ E
Sbjct: 64 HNQ-KEKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITE 122
Query: 254 KCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLK 313
+YY QII + ++HD +IHRDLK N+ L+ + VK+ DFG A ++ E
Sbjct: 123 FECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGE---- 178
Query: 314 YDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQ 373
R + GT Y++PE+L F DIW+ GC+++ ++ G+PPF+ T+
Sbjct: 179 -----RKKTLCGTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYS 233
Query: 374 KVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQF 416
K+ K ++ + D+V +L NPE R I Q+ +F
Sbjct: 234 KIKKCEYRVPSYLRKPAADMVIAMLQPNPESRPAIGQLLNFEF 276
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 137 bits (346), Expect = 6e-32
Identities = 80/264 (30%), Positives = 138/264 (51%), Gaps = 19/264 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK---QKKVKYVNIEKNTLQ 208
+ +K +T+G G+++ V LA + + + A+KI++K L QK + V I K
Sbjct: 119 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQL-- 176
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
+ I+ LY + E +LY +LEYA G++ + HG + EK + QI+ A+
Sbjct: 177 ---DHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ 233
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
++H K +IHRDLK EN+LLD DM +K+ DFG + + L + ++F G+
Sbjct: 234 YLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSN----------TFSLGNKLDTFCGSPP 283
Query: 329 YVSPELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
Y +PEL + D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 284 YAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 343
Query: 388 MTVRDLVKNILIKNPERRLLINQI 411
+L+K L+ NP+RR ++ I
Sbjct: 344 TDCENLLKKFLVINPQRRSSLDNI 367
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 137 bits (346), Expect = 6e-32
Identities = 80/264 (30%), Positives = 138/264 (51%), Gaps = 19/264 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK---QKKVKYVNIEKNTLQ 208
+ +K +T+G G+++ V LA + + + A+KI++K L QK + V I K
Sbjct: 167 VGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQL-- 224
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
+ I+ LY + E +LY +LEYA G++ + HG + EK + QI+ A+
Sbjct: 225 ---DHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ 281
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
++H K +IHRDLK EN+LLD DM +K+ DFG + + L + ++F G+
Sbjct: 282 YLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSN----------TFSLGNKLDTFCGSPP 331
Query: 329 YVSPELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
Y +PEL + D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 332 YAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 391
Query: 388 MTVRDLVKNILIKNPERRLLINQI 411
+L+K L+ NP+RR ++ I
Sbjct: 392 TDCENLLKKFLVINPQRRSSLDNI 415
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 137 bits (345), Expect = 8e-32
Identities = 83/267 (31%), Positives = 137/267 (51%), Gaps = 9/267 (3%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ ++ G TLG+G+ + V A + + +A+KI+ K + + + E TL+ LK
Sbjct: 8 VGKYELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVLK 67
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ L+ ++ +Y +LE GDL + G ++E + Q+ID + + H
Sbjct: 68 HPN-IVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCH 126
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+KGV HRDLK EN+LLD +K+TDFG + L ED L + + G+ YV+
Sbjct: 127 NKGVFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLH-------TTCGSPNYVA 179
Query: 332 PELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE+L N+ Y DIW+ G IL+ ++ G PF N + +K+ K +
Sbjct: 180 PEVLANEGYDGAASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPPIPRWISLGA 239
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
+ ++K +L NP R+ I IKAH +F
Sbjct: 240 KTMIKRMLDPNPVTRVTIAGIKAHDWF 266
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 137 bits (345), Expect = 8e-32
Identities = 92/328 (28%), Positives = 159/328 (48%), Gaps = 34/328 (10%)
Query: 140 TGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKY 199
T KI+ + + + ++ +T+G G+++ V LAT+I + K A+KI++K L ++ Y
Sbjct: 27 TSKISVDKLLR-VGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEE----Y 81
Query: 200 VNIEKNTLQRLKNTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+N + LK+ + I LY + +S +Y + EYAPNG++ + +G + E
Sbjct: 82 LNKTFREIAILKSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAA 141
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLL 317
Q++ A+ + H +GV+HRDLK EN+LLD DM +KL DFG + Y+
Sbjct: 142 RVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGFSN----------HYEEG 191
Query: 318 TRSNSFVGTAEYVSPELLND-NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM 376
++ G+ Y +PE+ Y + DIW+ G +L+ ++ G PF +V+
Sbjct: 192 ATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILELKSRVV 251
Query: 377 KVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPEL- 435
+F L++N+L+ P+RR I QI H++ ++ W + E
Sbjct: 252 LGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSE--------WQSEMQEQE 303
Query: 436 -------GPYKVSARALQSSVPKVASSP 456
G VS A SS+ + SP
Sbjct: 304 RFGDMSPGSGTVSKSASTSSLGSASDSP 331
>YPR111w [R] KOG0605 NDR and related serine/threonine kinases
Length = 564
Score = 137 bits (344), Expect = 1e-31
Identities = 86/319 (26%), Positives = 150/319 (46%), Gaps = 40/319 (12%)
Query: 143 ITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNI 202
+ K+ +K DF+ +G G Y V LA +S++ A+KILNK+ L K + +V
Sbjct: 157 LRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICALKILNKKLLFKLNETNHVLT 216
Query: 203 EKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQ 262
E++ L ++ ++ L + FQD SLY +E+ P GD +L+ + ++Y ++
Sbjct: 217 ERDILTTTRSD-WLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINTRILKSGHARFYISE 275
Query: 263 IIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTA--------------------- 301
+ A+ +H+ G HRDLKPEN L+D +KLTDFG A
Sbjct: 276 MFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKN 335
Query: 302 ----RLLDSTSED------DLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGC 351
+ + ED +++ + +NS VG+ +Y++ E+L DF D W+ GC
Sbjct: 336 LEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGC 395
Query: 352 ILFQMIAGKPPFKANNEYLTFQKVMKVQFAF--------TAGFPMTVRDLVKNILIKNPE 403
+LF+ + G PF ++ T++ + + A F DL+ ++
Sbjct: 396 MLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPIN 455
Query: 404 RRLLINQIKAHQFFADVNF 422
R Q++ +FA++NF
Sbjct: 456 RVRSFEQVRKMSYFAEINF 474
>SPBC1861.09 [R] KOG0610 Putative serine/threonine protein kinase
Length = 526
Score = 137 bits (344), Expect = 1e-31
Identities = 92/292 (31%), Positives = 144/292 (48%), Gaps = 32/292 (10%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG G V L +++ +A+KILNK +IK+ KV V E+ L + K+ I++LY
Sbjct: 161 LGQGDVGKVYLVRQKSNHRLFAMKILNKREMIKRHKVNRVLAEQEILTKSKHPF-IVTLY 219
Query: 221 FTFQDESSLYFLLEYAPNGDL---LSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIH 277
+FQ LY +EY G+ L + KH + EK +YAA++ AL ++H G I+
Sbjct: 220 HSFQSRDYLYLCMEYCAGGEFFRALHSLPKH-ILPEKDACFYAAEVTAALEYLHLMGFIY 278
Query: 278 RDLKPENILLDVDMKVKLTDFGTARLLDSTSE------------------DDLKYDLLTR 319
RDLKPENILL + L+DF ++ + + D Y R
Sbjct: 279 RDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFSQEKPALDTNSYFSNFR 338
Query: 320 SNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVM--K 377
+NSFVGT EY++PE++ D W G +++++ G PFK N + TF ++
Sbjct: 339 TNSFVGTEEYIAPEVIRSCGHTVAVDWWTLGIFIYEILYGTTPFKGKNRHATFSNILYSD 398
Query: 378 VQFAFTAGFP---MTVRDLVKNILIKNPERR----LLINQIKAHQFFADVNF 422
V F G P T + L++ +L+K+ +R + IK H FF + +
Sbjct: 399 VSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGASDIKQHPFFRHIQW 450
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 136 bits (343), Expect = 1e-31
Identities = 87/307 (28%), Positives = 149/307 (48%), Gaps = 30/307 (9%)
Query: 110 LPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTV 169
+ I Q ++KE +D AA K + ++DF G+ LG G + V
Sbjct: 1 MAIPTETQHQEKEASDASAAAAQK---------------RWTLSDFDIGKPLGRGKFGHV 45
Query: 170 LLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSL 229
LA SN A+K+L K L +Q +V++ + +Q I+ LY F D+ +
Sbjct: 46 YLAREKRSNHVVALKVLFKSQL-QQSQVEHQLRREVEIQSHLRHPNILRLYGYFYDQKRV 104
Query: 230 YFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDV 289
Y +LEYA G+L ++K +E+ Y A + AL + H K VIHRD+KPEN+L+
Sbjct: 105 YLILEYAARGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGA 164
Query: 290 DMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAF 349
++K+ DFG + R + GT +Y+ PE++ D DIW+
Sbjct: 165 QGELKIADFGWS------------VHTFNRRRTMCGTLDYLPPEMVESVEHDASVDIWSL 212
Query: 350 GCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG--FPMTVRDLVKNILIKNPERRLL 407
G + ++ + G PPF+A T++++++V F + +DL+ +L+K +RL
Sbjct: 213 GILCYEFLYGVPPFEAMEHSDTYRRIVQVDLKFPPKPIISASAKDLISQMLVKESSQRLP 272
Query: 408 INQIKAH 414
++++ H
Sbjct: 273 LHKLLEH 279
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 136 bits (342), Expect = 2e-31
Identities = 100/377 (26%), Positives = 187/377 (49%), Gaps = 53/377 (14%)
Query: 62 PPVL------TKALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELPISES 115
PPVL T ++ ++ ISL+ K N ++S + + S R N+
Sbjct: 35 PPVLVVEMSQTSSIGSAESLISLERKKEKNINRDITSRKDLPS-RTSNVE---------- 83
Query: 116 MQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGI---NDFKFGETLGDGSYSTVLLA 172
+ Q++W RG + GK+ I+ G + FG LG GS+ V+ A
Sbjct: 84 RKASQQQWG-RG---------NFTEGKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEA 133
Query: 173 TSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFL 232
T E+ K+A+K +NKE VK + E N L+ +K+ + II L F+ +Y +
Sbjct: 134 TDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKH-EHIIHLEQVFETPKKMYLV 191
Query: 233 LEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILL----- 287
+E +G+L ++ + G +E T++ + A+ ++H+ ++HRDLK ENI++
Sbjct: 192 MELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLI 251
Query: 288 ----DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFR 343
++++ +K+TDFG A S SE L+ + GT Y++PE+++ + +
Sbjct: 252 DDNNEINLNIKVTDFGLAVKKQSRSEAMLQ--------ATCGTPIYMAPEVISAHDYSQQ 303
Query: 344 CDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIK--- 400
CDIW+ G +++ ++ G+PPF A++E F+ + K + F ++ D K++L +
Sbjct: 304 CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMK 363
Query: 401 -NPERRLLINQIKAHQF 416
+P R+ ++ +Q+
Sbjct: 364 VDPAHRITAKELLDNQW 380
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 136 bits (342), Expect = 2e-31
Identities = 84/279 (30%), Positives = 139/279 (49%), Gaps = 26/279 (9%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ D+ G +G GS++ V LA S + AVK ++K+ L KV+ +++ ++
Sbjct: 7 VGDYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLL--SPKVRDNLLKEISILSTI 64
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ II Y + ++ +LEY GDL + +HG V E +++ Q+ L +
Sbjct: 65 DHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQ 124
Query: 272 DKGVIHRDLKPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
+K IHRDLKP+N+LL +V +K+ DFG AR L S + +F G+
Sbjct: 125 EKHFIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPES----------MAETFCGSPL 174
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
Y++PE++ + D + D+W+ G ILFQ++ GKPPF NN F +++ FP
Sbjct: 175 YMAPEIIRNQKYDAKADLWSAGAILFQLVTGKPPFDGNNHIQLFHNIVR---DTELKFPE 231
Query: 389 TVR--------DLVKNILIKNPERRLLINQIKAHQFFAD 419
R DL +++L +NP RL + H F +
Sbjct: 232 DTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLRE 270
>SPAC4G8.05 [R] KOG0610 Putative serine/threonine protein kinase
Length = 566
Score = 135 bits (341), Expect = 2e-31
Identities = 105/372 (28%), Positives = 176/372 (47%), Gaps = 54/372 (14%)
Query: 148 IKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTL 207
++ G + F+ LG G V L +S K YA+K+L+K+ +IK+ K K E++ L
Sbjct: 188 VEVGPSSFEKVFLLGKGDVGRVYLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHIL 247
Query: 208 QRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLL-SLMRKHGS-VNEKCTQYYAAQIID 265
N I++LY +FQ + LY +EY G+ +L R+ G ++E ++Y A++
Sbjct: 248 AT-SNHPFIVTLYHSFQSDEYLYLCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTA 306
Query: 266 ALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDL-----------KY 314
AL ++H G I+RDLKPENILL + L+DF ++ +S + Y
Sbjct: 307 ALEYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAPSAQNAY 366
Query: 315 DLLTRS-------NSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANN 367
L T+S NSFVGT EY++PE++ D W G + ++M+ PFK N
Sbjct: 367 ALDTKSCIADFRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKN 426
Query: 368 EYLTFQKVMK-----VQFAFTAGFPMTVRDLVKNILIKNPERRLLIN----QIKAHQFFA 418
+TF ++ ++A ++L++ +L+K+ RL +K H FF
Sbjct: 427 RNMTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFK 486
Query: 419 DVNFGNGSVWDKDPPELGPYKVSARALQSSVPKVA-----SSPAINPIHEPVRQSSVSPK 473
+V + + +PP +PK+A +P I+ + E S+
Sbjct: 487 NVQW--ALLRHTEPP--------------IIPKLAPIDEKGNPNISHLKE---SKSLDIT 527
Query: 474 ITPKNTTTAQRP 485
+P+NT T + P
Sbjct: 528 HSPQNTQTVEVP 539
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 135 bits (341), Expect = 2e-31
Identities = 84/291 (28%), Positives = 151/291 (51%), Gaps = 28/291 (9%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK---QKKVKYVNIEKNTLQ 208
I +++ +T+G G+++ V LA + + ++ AVKI++K L QK + V I K
Sbjct: 57 IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK---- 112
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
+ N I+ L+ + E +LY ++EYA G++ + HG + EK + QI+ A+
Sbjct: 113 -ILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ 171
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
+ H K ++HRDLK EN+LLD DM +K+ DFG + ++ + + ++F G+
Sbjct: 172 YCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSN----------EFTVGNKLDTFCGSPP 221
Query: 329 YVSPELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
Y +PEL D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 222 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 281
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
+L+K +L+ NP +R + QI ++ +N G+ + EL PY
Sbjct: 282 TDCENLLKKLLVLNPIKRGSLEQIMKDRW---MNVGH------EEEELKPY 323
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 135 bits (339), Expect = 4e-31
Identities = 90/288 (31%), Positives = 147/288 (50%), Gaps = 25/288 (8%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF + +G G++ V + I + K YA+KILNK ++K+ + E++ L +
Sbjct: 98 DDFDILKIIGRGAFGEVCVVQMISTEKVYAMKILNKWEMLKRAETACFREERDVLV-FGD 156
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRK-HGSVNEKCTQYYAAQIIDALGFMH 271
+ I +L++ FQD +LY +++Y GDLL+L+ K + E ++Y ++I A+ +H
Sbjct: 157 RQWITNLHYAFQDNINLYLVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIH 216
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+HRD+KP+N+LLD V+L DFG+ LD D +SN VGT +Y+S
Sbjct: 217 QIRYVHRDIKPDNVLLDKRGHVRLADFGSCLRLDK--------DGTVQSNVAVGTPDYIS 268
Query: 332 PELL-----NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF 386
PE+L CD W+ G +++M+ G+ PF A + T+ K+M Q F
Sbjct: 269 PEILRAMEDGKGRYGTECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHQNCFNLPS 328
Query: 387 PMTVRDLVKNI-------LIKNPERRLLINQIK---AHQFFADVNFGN 424
T+ V LI PE RL N I+ H +F +++ N
Sbjct: 329 QETLNYKVSETSQDLLCKLICIPENRLGQNGIQDFMDHPWFVGIDWKN 376
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 134 bits (338), Expect = 5e-31
Identities = 78/271 (28%), Positives = 148/271 (53%), Gaps = 20/271 (7%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
F+F ETLG G++S V+LA + K +AVK + K+ L + K + E L+++K+ +
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL--KGKESSIENEIAVLRKIKH-E 79
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I++L ++ + LY +++ G+L + + G EK Q++DA+ ++H G
Sbjct: 80 NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMG 139
Query: 275 VIHRDLKPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
++HRDLKPEN+L D + K+ ++DFG +++ + K D+++ + GT YV+
Sbjct: 140 IVHRDLKPENLLYYSQDEESKIMISDFGLSKM-------EGKGDVMSTA---CGTPGYVA 189
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF----P 387
PE+L D W+ G I + ++ G PPF N+ F++++K ++ F + +
Sbjct: 190 PEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDIS 249
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFA 418
+ +D ++N++ K+P +R Q H + A
Sbjct: 250 DSAKDFIRNLMEKDPNKRYTCEQAARHPWIA 280
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 134 bits (338), Expect = 5e-31
Identities = 80/288 (27%), Positives = 156/288 (53%), Gaps = 22/288 (7%)
Query: 149 KKGINDFKFGETLGDGSYSTVLL---ATSIESNKKYAVKILNKEYLIKQKKVK-YVNIEK 204
K + +F+ + LG G+Y V L A ++ K YA+K+L K L+++ K + + E+
Sbjct: 27 KVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86
Query: 205 NTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQII 264
+ L+ ++ +++L++ FQ ++ L+ +L+Y G++ + + + E + Y +I+
Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIV 146
Query: 265 DALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFV 324
AL +H G+I+RDLK EN+LLD + + LTDFG ++ + ++ R+ SF
Sbjct: 147 LALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKE--------RTFSFC 198
Query: 325 GTAEYVSPELLNDNYVDFRC-DIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT 383
GT EY++PE++ + D W+ G +LF+++ G PF E T +V + +
Sbjct: 199 GTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCS 258
Query: 384 AGFPMTV----RDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
FP + +DL++ +L K+P++RL +++ H FF +++
Sbjct: 259 PPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDW 306
Score = 110 bits (274), Expect = 1e-23
Identities = 76/274 (27%), Positives = 131/274 (47%), Gaps = 29/274 (10%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG GS+S +S +++AVKIL++ ++ E L+ ++ +++L+
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQR------EVAALRLCQSHPNVVNLH 470
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK-GVIHRD 279
D+ Y +LE G+LL +RK +E ++ A+ FMH++ GV+HRD
Sbjct: 471 EVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRD 530
Query: 280 LKPENILLDVDMK---VKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLN 336
LKPENIL D VK+ DFG ARL + ++ T +Y +PELL
Sbjct: 531 LKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFT--------LQYAAPELLA 582
Query: 337 DNYVDFRCDIWAFGCILFQMIAGKPPFKA-------NNEYLTFQKVMKVQFAFTA----G 385
D CD+W+ G IL+ M++G+ PF+ + K+ + +F+ G
Sbjct: 583 QQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQG 642
Query: 386 FPMTVRDLVKNILIKNPERRLLINQIKAHQFFAD 419
++LV+ +L +P +RL + ++ + D
Sbjct: 643 VSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQD 676
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 134 bits (338), Expect = 5e-31
Identities = 80/308 (25%), Positives = 151/308 (48%), Gaps = 21/308 (6%)
Query: 142 KITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVN 201
K V G +K +TLG G+++ V LA + + ++ A+K+++K L + K
Sbjct: 85 KFQSYVNGNGNGVYKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYR 144
Query: 202 IEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAA 261
K + +L N I+ L+ + E +LY ++EYA G+L + K+G + E+ +
Sbjct: 145 EVK--IMKLLNHPNIVRLFQVIESERTLYLVMEYASRGELFDHLVKNGRMRERDARVIFR 202
Query: 262 QIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSN 321
Q++ A+ + H K V+HRDLK EN+LLD M +K+ DFG D ++
Sbjct: 203 QLVSAIQYCHSKFVVHRDLKAENLLLDQHMNIKIADFGFGNTFDPNAQ----------LE 252
Query: 322 SFVGTAEYVSPEL-LNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQF 380
+F G+ Y +PEL + Y D W+ G +L+ +++G PF ++V++ ++
Sbjct: 253 TFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVSGSLPFDGGTLKELRERVLRGKY 312
Query: 381 AFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKV 440
M +L++ L+ NP +R ++ + + ++ +N G+ + L P++
Sbjct: 313 RVPYYISMDCENLMRKFLVLNPAKRTSLSAVMSDKW---INLGH-----DESDRLRPFRE 364
Query: 441 SARALQSS 448
LQ +
Sbjct: 365 KPMELQDA 372
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 134 bits (337), Expect = 6e-31
Identities = 82/273 (30%), Positives = 144/273 (52%), Gaps = 15/273 (5%)
Query: 145 KQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEK 204
K+ ++ G D + T+G G+++ V LA + + A+KI++K L Q ++ V E
Sbjct: 133 KEPMRVGFYDIE--RTIGKGNFAVVKLARHRITKNEVAIKIIDKSQL-DQTNLQKVYREV 189
Query: 205 NTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQII 264
++RLK+ II LY + ++ +Y + EYA G++ + K+G ++E ++ QII
Sbjct: 190 EIMKRLKHPH-IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQII 248
Query: 265 DALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFV 324
A+ + H KG++HRDLK EN+LLD++M +K+ DFG S +LL ++
Sbjct: 249 SAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFG-------FSNHFKPGELLA---TWC 298
Query: 325 GTAEYVSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT 383
G+ Y +PE+ Y DIW+ G +L+ ++ G PF + +V+ +F
Sbjct: 299 GSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIP 358
Query: 384 AGFPMTVRDLVKNILIKNPERRLLINQIKAHQF 416
L++ +L+ P RR I+QIK H++
Sbjct: 359 FFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRW 391
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 134 bits (336), Expect = 8e-31
Identities = 77/268 (28%), Positives = 136/268 (50%), Gaps = 15/268 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
++ F+ G LG G + V LA E A+KI+ + + + + + E LK
Sbjct: 7 LDRFEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRREIEIHSNLK 66
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMR-KHGSVNEKCTQYYAAQIIDALGFM 270
+ I+ +Y F D+ ++Y +LEYA G+ + + G EK T Y Q++ AL +M
Sbjct: 67 HPN-ILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKFGEKETSLYIRQVMLALTYM 125
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
+ VIHRD+KPEN+LL D ++K+ DFG A Y+ R +F GT EY+
Sbjct: 126 KECNVIHRDIKPENLLLGSDNQLKIADFGWA-----------VYNADKRRMTFCGTMEYL 174
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYL--TFQKVMKVQFAFTAGFPM 388
+PE++N++ D D+W G + ++ + GK PF++ N + ++K+ +++
Sbjct: 175 APEMVNNDIHDSGIDLWCLGILTYEFLMGKTPFESKNRNMREAYKKINSLKYTIPETISS 234
Query: 389 TVRDLVKNILIKNPERRLLINQIKAHQF 416
D + +L+ +P R+ + + H F
Sbjct: 235 NASDFISRLLVLSPGDRMELTEALNHPF 262
>CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 615
Score = 134 bits (336), Expect = 8e-31
Identities = 73/263 (27%), Positives = 134/263 (50%), Gaps = 11/263 (4%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG+G ++ ++ N + AVK++ K L+K + + E ++L + +
Sbjct: 35 YEKGAFLGEGGFAHCFEFRKLDCNDRLAVKVVPKVILLKSTAREKLTREVEIHRQLSH-R 93
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ + F+D ++YF LE L+ L ++ G + E ++Y Q+ + + +H+
Sbjct: 94 NIVQFHHFFEDSQNVYFTLELCSKNSLMELNKQRGPLTEHEARFYTIQVAEGVKHLHNLQ 153
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
+IHRDLK N+ L+ ++VK+ DFG A + + +TR GT Y++PE+
Sbjct: 154 IIHRDLKLGNLFLNEHLQVKIGDFGLATFCEKNEKK------MTRG----GTPNYIAPEV 203
Query: 335 LNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLV 394
LN+ F DIWA GCIL+ ++ G PPF++ T+ ++ + T L+
Sbjct: 204 LNETGHAFEVDIWAIGCILYVLLFGSPPFESRRVQETYVRIKNNDYVVPENASPTANRLI 263
Query: 395 KNILIKNPERRLLINQIKAHQFF 417
+++L P+RR + QFF
Sbjct: 264 RSLLDPVPDRRPTAEAVLLDQFF 286
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 134 bits (336), Expect = 8e-31
Identities = 86/289 (29%), Positives = 138/289 (46%), Gaps = 32/289 (11%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYL---------------IKQKKVKY 199
++ G +G G++S+V L E K A+K+ + L + K +
Sbjct: 57 YEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSFPSKFFQQVEKRAMRGKCFF 116
Query: 200 VNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYY 259
V+ E L +++ IIS+ F E+ + + E+A GDL +RK+G + E
Sbjct: 117 VDNEVEMLSLIQHDH-IISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAII 175
Query: 260 AAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTR 319
Q+ AL ++H++ V+HRD+KPEN+LL VKL DFG L +L
Sbjct: 176 TLQVASALNYLHERNVVHRDVKPENLLLVDKFSVKLCDFG------------LACHILGP 223
Query: 320 SNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMK-- 377
GT Y +PE+L + RCDIW+ G +L+ M+ G PF+A ++ F+ +M+
Sbjct: 224 LYRICGTPTYCAPEVLRETGYSTRCDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAK 283
Query: 378 --VQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGN 424
+ G + +DLV ++ K ERR L +QI AH + A N
Sbjct: 284 PNLDMPEWKGISLKAKDLVSRLMNKTEERRPLASQIMAHPWIAPYTMEN 332
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 134 bits (336), Expect = 8e-31
Identities = 80/291 (27%), Positives = 146/291 (49%), Gaps = 30/291 (10%)
Query: 137 DKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKK 196
D + + ++ + ++K G+TLG GS+ V +A + + K A+KILN+ +K
Sbjct: 2 DHSSNRFGNNGVESILPNYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNR------RK 55
Query: 197 VKYVNIEKNTLQRLKNTK-----GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
+K + +E+ + +K + II Y + S +Y ++EY +G+L + + G +
Sbjct: 56 IKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRL 115
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
E + + QII + + H V+HRDLKPEN+LLD +K+ DFG + ++
Sbjct: 116 QEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVM------- 168
Query: 312 LKYDLLTRSNSFV----GTAEYVSPELLNDN-YVDFRCDIWAFGCILFQMIAGKPPFKAN 366
R F+ G+ Y +PE+++ Y D+W+ G IL+ ++ G PF
Sbjct: 169 -------RDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE 221
Query: 367 NEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
N F+K+ + + RDL+ +LI +P +R+ I +I+ H++F
Sbjct: 222 NIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITIPEIRQHRWF 272
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 134 bits (336), Expect = 8e-31
Identities = 96/365 (26%), Positives = 169/365 (46%), Gaps = 36/365 (9%)
Query: 52 SEMKPFGKPNPPVLTKALTDVDNFISLDPKYLNRRNDSLSSVETIDSTRDDNISIPKELP 111
SE F KP P + K ++ F + P ++ +SLS + ++ + + KEL
Sbjct: 73 SEGNNFQKPMVPSVKKTTSE---FAAPAPVAPIKKPESLSKQKPTAASSESS----KELG 125
Query: 112 ISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLL 171
+ S ++K K Q K T + +N+F G LG G + V L
Sbjct: 126 AASSSAEKEK----------TKTETQPQKPKKTWE-----LNNFDIGRLLGRGKFGNVYL 170
Query: 172 ATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYF 231
A ES A+K+L K + + V E L++ I+ LY F D+ +Y
Sbjct: 171 AREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHPH-ILRLYAYFHDDVRIYL 229
Query: 232 LLEYAPNGDLLSLMRKHGS--VNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDV 289
+LEYAP G L + ++ +E+ + Y + AL ++H++ +IHRD+KPEN+LL
Sbjct: 230 ILEYAPQGTLFNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGH 289
Query: 290 DMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAF 349
+K+ DFG + ++ + + GT +Y+ PE++ D+W+
Sbjct: 290 KGVLKIADFGWS-----------VHEPNSMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSL 338
Query: 350 GCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLIN 409
G + F+++ G PF + N T++K++KV + L+ +L+ NP+ RL ++
Sbjct: 339 GVLCFELLVGHAPFYSKNYDETYKKILKVDYKLPEHISKAASHLISKLLVLNPQHRLPLD 398
Query: 410 QIKAH 414
Q+ H
Sbjct: 399 QVMVH 403
>SPCC417.06c [R] KOG0605 NDR and related serine/threonine kinases
Length = 624
Score = 133 bits (334), Expect = 1e-30
Identities = 71/234 (30%), Positives = 126/234 (53%), Gaps = 29/234 (12%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG G Y +V LA +++ A+K++ K L + +VK++ E++ L N++ ++ LY
Sbjct: 168 LGQGGYGSVWLAKKRNTHELLAMKMMKKSTLQQLNEVKHILNERDILTNT-NSEWLVKLY 226
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
+ FQD+ +Y +EY P GD + + G ++E T++Y A+++ A+ +H G +HRDL
Sbjct: 227 YAFQDKEKVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVHKLGYMHRDL 286
Query: 281 KPENILLDVDMKVKLTDFG-TARLLDSTSEDDLKYDLLT--------------------- 318
KPEN L+D +KL+DFG + ++ S + L++ L++
Sbjct: 287 KPENFLIDQKGHIKLSDFGLSTAIVTSNQVNRLQHALVSAVNPQRPYLTQKQRRNIYKAL 346
Query: 319 ------RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKAN 366
+ NS VG+ EY++PE++ D D W+ GCI ++ + G PPF +
Sbjct: 347 LEKNENKVNSVVGSPEYMAPEVVYGKKYDRTVDYWSLGCICYECLVGYPPFSGS 400
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 133 bits (334), Expect = 1e-30
Identities = 82/271 (30%), Positives = 138/271 (50%), Gaps = 22/271 (8%)
Query: 149 KKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
K I ++ G+TLG GS S V LA ++ A+KI+ ++Y +I L
Sbjct: 6 KNTIGVWRLGKTLGTGSTSCVRLAKHAKTGDLAAIKII---------PIRYASIGMEILM 56
Query: 209 -RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDAL 267
RL I+ LY + D +Y LEY P+G+L +RKHG ++E+ +Y +QI+DA+
Sbjct: 57 MRLLRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAV 116
Query: 268 GFMHDKGVIHRDLKPENILLDV-DMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGT 326
H HRDLK ENIL+ V + ++K+ DFG A + + S ++ G+
Sbjct: 117 AHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMATVEPNDS----------CLENYCGS 166
Query: 327 AEYVSPELLNDN-YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG 385
Y++PE+++ Y D+W+ G IL+ +++ K PF N + + K+ + +
Sbjct: 167 LHYLAPEIVSHKPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSS 226
Query: 386 FPMTVRDLVKNILIKNPERRLLINQIKAHQF 416
+DL+ +L NP R+ I ++ +H F
Sbjct: 227 ISSAAQDLLHRMLDVNPSTRITIPEVFSHPF 257
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 133 bits (334), Expect = 1e-30
Identities = 79/263 (30%), Positives = 143/263 (54%), Gaps = 13/263 (4%)
Query: 150 KGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQR 209
K I ++ G T+G+G+++ V L + AVKI++K +I++ V E T+ +
Sbjct: 7 KKIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTM-K 65
Query: 210 LKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGF 269
L N I+ ++ ++ + ++EY G L + + + E + Q+IDA+ +
Sbjct: 66 LLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQ-KMKESDARKLFQQLIDAVDY 124
Query: 270 MHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
H++GV HRDLKP+N+LLD +K++DFG + + S D+L+ + G+ Y
Sbjct: 125 CHNRGVYHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSG-------DMLSTA---CGSPCY 174
Query: 330 VSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
++PEL+ N Y D+W+ G ILF+++AG PPF + + ++K+++ + F GF
Sbjct: 175 IAPELIMNKGYSGAAVDVWSCGVILFELLAGYPPFDDHTLPVLYKKILRADYTFPPGFTG 234
Query: 389 TVRDLVKNILIKNPERRLLINQI 411
+ L+ NIL NP R+ + +I
Sbjct: 235 EQKRLIFNILDPNPLSRITLAEI 257
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 133 bits (334), Expect = 1e-30
Identities = 78/264 (29%), Positives = 135/264 (50%), Gaps = 15/264 (5%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF G+ LG G + V LA S+ A+K+L K L +Q +V++ + +Q
Sbjct: 17 SDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQL-QQSQVEHQLRREVEIQSHLR 75
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
I+ LY F D+ +Y +LEYA G+L ++K +E+ Y A + AL + H
Sbjct: 76 HPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHG 135
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
K VIHRD+KPEN+L+ ++K+ DFG + R + GT +Y+ P
Sbjct: 136 KHVIHRDIKPENLLIGAQGELKIADFGWS------------VHTFNRRRTMCGTLDYLPP 183
Query: 333 ELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG--FPMTV 390
E++ D DIW+ G + ++ + G PPF+A T++++++V F +
Sbjct: 184 EMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVSSSA 243
Query: 391 RDLVKNILIKNPERRLLINQIKAH 414
+DL+ +L+K +RL ++++ H
Sbjct: 244 KDLISQMLVKESTQRLALHKLLEH 267
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 133 bits (334), Expect = 1e-30
Identities = 80/271 (29%), Positives = 143/271 (52%), Gaps = 18/271 (6%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG G + T + ++YA K ++K LI++K ++ V E LQ L I+
Sbjct: 91 LGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVEFR 150
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
++D+ +L+ ++E G+L + K GS +EK QI++ + H GV+HRDL
Sbjct: 151 GAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVVHVCHFMGVVHRDL 210
Query: 281 KPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLND 337
KPEN LL + D +K TDFG + ++ E + D+ VG+A YV+PE+L+
Sbjct: 211 KPENFLLVSNEEDSPIKATDFGLSVFIE---EGKVYRDI-------VGSAYYVAPEVLHR 260
Query: 338 NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF-TAGFPM---TVRDL 393
NY D+W+ G +L+ +++G PPF E F+ +++ + T+ +P + +DL
Sbjct: 261 NY-GKEIDVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDL 319
Query: 394 VKNILIKNPERRLLINQIKAHQFFADVNFGN 424
++ +LI++P++R+ + H + D +
Sbjct: 320 IRKMLIRDPKKRITAAEALEHPWMTDTKISD 350
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 132 bits (333), Expect = 2e-30
Identities = 81/280 (28%), Positives = 146/280 (51%), Gaps = 15/280 (5%)
Query: 142 KITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVN 201
K +IK D+ G LG+G ++ +S + +A K + K IK +K +
Sbjct: 69 KTPPSLIKTRGKDYHRGHFLGEGGFARCFQIKD-DSGEIFAAKTVAKAS-IKSEKTRKKL 126
Query: 202 IEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAA 261
+ + + + + I+ F+D+S++Y LLE PNG L+ L+++ + E +++
Sbjct: 127 LSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTT 186
Query: 262 QIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSN 321
QI A+ +MH + VIHRDLK NI D + +K+ DFG A +L + SE R
Sbjct: 187 QICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESE---------RKY 237
Query: 322 SFVGTAEYVSPELLNDNYV--DFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQ 379
+ GT Y++PE+L + F DIW+ G +L+ ++ GKPPF+A + ++++
Sbjct: 238 TICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCRD 297
Query: 380 FAFTAGFPMT--VRDLVKNILIKNPERRLLINQIKAHQFF 417
F+F P++ + L+++IL +P R + +I + +F
Sbjct: 298 FSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWF 337
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 132 bits (333), Expect = 2e-30
Identities = 77/264 (29%), Positives = 138/264 (52%), Gaps = 19/264 (7%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK---QKKVKYVNIEKNTLQ 208
I +++ +T+G G+++ V LA I + ++ A+KI++K L QK + V I K
Sbjct: 53 IGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMK---- 108
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
+ N I+ L+ + + +LY ++EYA G + + HG + EK + QI+ A+
Sbjct: 109 -ILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQ 167
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
+ H K ++HRDLK EN+LLD DM +K+ DFG + ++ + + ++F G+
Sbjct: 168 YCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN----------EFTVGGKLDTFCGSPP 217
Query: 329 YVSPELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
Y +PEL D D+W+ G IL+ +++G PF N ++V++ ++
Sbjct: 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 277
Query: 388 MTVRDLVKNILIKNPERRLLINQI 411
+L+K L+ NP +R + QI
Sbjct: 278 TDCENLLKRFLVLNPIKRGTLEQI 301
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 132 bits (333), Expect = 2e-30
Identities = 75/267 (28%), Positives = 134/267 (50%), Gaps = 19/267 (7%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQ----KKVKYVNIEKNTLQRL 210
++ G+ LG G ++ + + + +A K++ K LIKQ K + V I +N R
Sbjct: 36 YEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHR- 94
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
++ LY F+D+S++Y LE P L+ L ++ +V E +Y+ QI++ + ++
Sbjct: 95 ----NVVKLYHFFEDKSNVYITLELCPRRSLMELHKRRKAVTEPEARYFTYQIVEGVLYL 150
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H+ ++HRDLK N+ L+ +++VK+ DFG A D+ R + GT Y+
Sbjct: 151 HNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCDNDE----------RKKTLCGTPNYI 200
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
+PE+LN F D+WA GCIL+ ++ G PPF++ + T+ ++ +
Sbjct: 201 APEVLNKIGHSFEVDLWAIGCILYILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAA 260
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
L++ +L P RR + FF
Sbjct: 261 SQLIRVLLDPVPSRRPNARAVCRDHFF 287
>CE11916 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1548
Score = 132 bits (333), Expect = 2e-30
Identities = 86/299 (28%), Positives = 156/299 (51%), Gaps = 32/299 (10%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF+ + +G G++ V + + YA+KILNK ++K+ + E++ L +
Sbjct: 81 DDFEVLKVIGKGAFGEVAVVRMRGVGEIYAMKILNKWEMVKRAETACFREERDVLV-YGD 139
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKH-GSVNEKCTQYYAAQIIDALGFMH 271
+ I +L++ FQDE +LYF+++Y GD+L+L+ K + E ++Y A+++ A+ +H
Sbjct: 140 RRWITNLHYAFQDEKNLYFVMDYYIGGDMLTLLSKFVDHIPESMAKFYIAEMVLAIDSLH 199
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTA-RLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
G +HRD+KP+N+LLD+ ++L DFG+ R+L S SN VGT +Y+
Sbjct: 200 RLGYVHRDVKPDNVLLDMQGHIRLADFGSCLRILADGS---------VASNVAVGTPDYI 250
Query: 331 SPELL-----NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG 385
SPE+L CD W+ G +++M+ G PF + T+ K+M Q
Sbjct: 251 SPEILRAMEDGRGRYGKECDWWSLGICMYEMLYGTTPFYSERLVDTYGKIMSHQDML--D 308
Query: 386 FP---------MTVRDLVKNILIKNPER--RLLINQIKAHQFFADVNFGNGSVWDKDPP 433
FP +DL++ ++ + R R ++ + H FF +++ ++ D +PP
Sbjct: 309 FPDDEIDWVVSEEAKDLIRQLICSSDVRFGRNGLSDFQLHPFFEGIDW--NTIRDSNPP 365
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 132 bits (332), Expect = 2e-30
Identities = 77/271 (28%), Positives = 142/271 (51%), Gaps = 20/271 (7%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
+ F + LG G++S V+LA + K A+K + KE L + K + E L ++K+
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEAL--EGKEGSMENEIAVLHKIKHPN 77
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I++L ++ LY +++ G+L + + G E+ Q++DA+ ++HD G
Sbjct: 78 -IVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136
Query: 275 VIHRDLKPENIL---LDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
++HRDLKPEN+L LD D K+ ++DFG +++ D S ++ GT YV+
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSV----------LSTACGTPGYVA 186
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF----P 387
PE+L D W+ G I + ++ G PPF N+ F++++K ++ F + +
Sbjct: 187 PEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDIS 246
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFA 418
+ +D +++++ K+PE+R Q H + A
Sbjct: 247 DSAKDFIRHLMEKDPEKRFTCEQALQHPWIA 277
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 132 bits (332), Expect = 2e-30
Identities = 70/244 (28%), Positives = 135/244 (54%), Gaps = 18/244 (7%)
Query: 195 KKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEK 254
++ ++V+ EK L +LK+ I+ +Y + +D + LY ++E+ P G++ S +R S +
Sbjct: 2 RQTQHVHNEKRVLLQLKHPF-IVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNS 60
Query: 255 CTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKY 314
++YA++I+ AL ++H G+++RDLKPEN++L + +K+ DFG A+
Sbjct: 61 MARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAK------------ 108
Query: 315 DLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQK 374
+L R+ + GT +Y++PE L + D WA G ++++M+ GKPPF+ +
Sbjct: 109 ELRDRTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDA 168
Query: 375 VMKVQFAFTAGFPMTVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNFGNGSVWD 429
+++ + F F + +DLVK +L + +R+ +K H++F VN+ +
Sbjct: 169 IIEHKLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLR 228
Query: 430 KDPP 433
+PP
Sbjct: 229 VEPP 232
>At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 490
Score = 132 bits (332), Expect = 2e-30
Identities = 81/278 (29%), Positives = 136/278 (48%), Gaps = 19/278 (6%)
Query: 150 KGINDFKF-GETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQ 208
K + D F G+ LG G + T L T ++ +K A K + K L+ Q+ V E +
Sbjct: 16 KNVEDNYFLGQVLGQGQFGTTFLCTHKQTGQKLACKSIPKRKLLCQEDYDDVLREIQIMH 75
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
L ++ + ++D +++ ++E G+L + K G +E+ I+ +
Sbjct: 76 HLSEYPNVVRIESAYEDTKNVHLVMELCEGGELFDRIVKRGHYSEREAAKLIKTIVGVVE 135
Query: 269 FMHDKGVIHRDLKPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVG 325
H GV+HRDLKPEN L D D +K TDFG + + VG
Sbjct: 136 ACHSLGVVHRDLKPENFLFSSSDEDASLKSTDFGLSVFCTPGE----------AFSELVG 185
Query: 326 TAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT-- 383
+A YV+PE+L+ +Y CD+W+ G IL+ ++ G PPF A +E F+K+++ + F
Sbjct: 186 SAYYVAPEVLHKHYGP-ECDVWSAGVILYILLCGFPPFWAESEIGIFRKILQGKLEFEIN 244
Query: 384 --AGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFAD 419
+ +DL+K +L NP++RL +Q+ H + D
Sbjct: 245 PWPSISESAKDLIKKMLESNPKKRLTAHQVLCHPWIVD 282
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 132 bits (331), Expect = 3e-30
Identities = 79/272 (29%), Positives = 144/272 (52%), Gaps = 22/272 (8%)
Query: 155 FKFGETLGDGSYSTVLLATS-IESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
+ F + LG G++S V LA S ++ + YAVK ++K+ L + K + + E L++L++
Sbjct: 22 YDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKAL--KGKEESLENEIKVLRKLRHN 79
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
I+ L+ T+ ++ +Y ++E G+L + GS E+ Q+++A+GFMHD
Sbjct: 80 N-IVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHDN 138
Query: 274 GVIHRDLKPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
GV+HRDLKPEN+L D D K+ ++DFG ++ DS + GT YV
Sbjct: 139 GVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSGV-----------MATACGTPGYV 187
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF---- 386
+PE+L D+W+ G I + ++ G PPF ++ F +++K ++ F A +
Sbjct: 188 APEVLQQKPYGKAVDVWSIGVIAYILLCGYPPFYDESDANLFAQIIKGEYEFDAPYWDQI 247
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFA 418
+ +D + +++ +PE R +H + +
Sbjct: 248 SDSAKDFITHLMCCDPEARFTCQDALSHPWIS 279
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 132 bits (331), Expect = 3e-30
Identities = 80/286 (27%), Positives = 144/286 (49%), Gaps = 22/286 (7%)
Query: 137 DKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKK 196
D + K T +++ + +++ G+TLG GS++ V LA + + K A+KILN+ K
Sbjct: 2 DGSSEKTTNKLVSI-LPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRS------K 54
Query: 197 VKYVNIEKNTLQRLKNTK-----GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV 251
+K + IE + +K + II Y + + +Y ++EY +G+L + + G +
Sbjct: 55 IKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKL 114
Query: 252 NEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDD 311
E ++ QII + + H ++HRDLKPEN+LLD +K+ DFG + ++
Sbjct: 115 QEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHD----- 169
Query: 312 LKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLT 371
+ L T G+ Y +PE+++ DIW+ G IL+ ++ G PF N
Sbjct: 170 -GHFLKTS----CGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNV 224
Query: 372 FQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
F+K+ + + RDL+ +L+ +P R+ I +I+ H +F
Sbjct: 225 FEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWF 270
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 132 bits (331), Expect = 3e-30
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 19/273 (6%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
+ G LG G + + T I S K +A K + K LI+ K + V E + L
Sbjct: 98 YSLGRELGRGQFGITYICTEISSGKNFACKSILKRKLIRTKDREDVRREIQIMHYLSGQP 157
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ + ++D S++ ++E G+L + K G +EK ++ + H G
Sbjct: 158 NIVEIKGAYEDRQSVHLVMELCEGGELFDKITKRGHYSEKAAAEIIRSVVKVVQICHFMG 217
Query: 275 VIHRDLKPENILL----DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
VIHRDLKPEN LL + +K TDFG + + E+ Y+ VG+A YV
Sbjct: 218 VIHRDLKPENFLLSSKDEASSMLKATDFGVSVFI----EEGKVYE------DIVGSAYYV 267
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTA----GF 386
+PE+L NY DIW+ G IL+ ++ G PPF A + F+++++ + F +
Sbjct: 268 APEVLKRNY-GKAIDIWSAGVILYILLCGNPPFWAETDKGIFEEILRGEIDFESEPWPSI 326
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFAD 419
+ +DLV+N+L +P++R Q+ H + +
Sbjct: 327 SESAKDLVRNMLKYDPKKRFTAAQVLEHPWIRE 359
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 131 bits (330), Expect = 4e-30
Identities = 85/279 (30%), Positives = 144/279 (51%), Gaps = 17/279 (6%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ ETLG G+Y V AT S + A+K + K+ + ++ + ++ E + L N
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSL-NHP 113
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
IIS+Y F+++ + ++EYA G+L + + ++E+ T+++ QI+ A+ + H G
Sbjct: 114 HIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNG 173
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
V+HRDLK ENILLD + +K+ DFG + L Y +F G+ Y SPE+
Sbjct: 174 VVHRDLKLENILLDDNCNIKIADFGLSNL----------YQKDKFLQTFCGSPLYASPEI 223
Query: 335 LNDN-YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDL 393
+N Y D WA G +L+ ++ G PF + +++ ++ P R L
Sbjct: 224 VNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGL 282
Query: 394 VKNILIKNPERRLLINQIKAHQFFADVNFG-NGSVWDKD 431
++ +L+ NP+RR I I H + VN+G SV D D
Sbjct: 283 IRWMLMVNPDRRATIEDIANHWW---VNWGYKSSVCDCD 318
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 131 bits (330), Expect = 4e-30
Identities = 73/260 (28%), Positives = 129/260 (49%), Gaps = 10/260 (3%)
Query: 158 GETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGII 217
G LG G ++ AT E+ YAVK++ + + K + + + + + L R + I+
Sbjct: 26 GRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKI-LNEIELHRDLQHRHIV 84
Query: 218 SLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIH 277
F+D ++Y LE L + + ++ E +YY QI+ L ++H +G++H
Sbjct: 85 RFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILH 144
Query: 278 RDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLND 337
RDLK N + +M++K+ DFG A L+ + R + GT YV+PE+L
Sbjct: 145 RDLKLGNFFITENMELKVGDFGLAARLEPPEQ---------RKKTICGTPNYVAPEVLLR 195
Query: 338 NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNI 397
D+W+ GC+++ ++ G PPF+ + T++ + +V + A + R L+ I
Sbjct: 196 QGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAI 255
Query: 398 LIKNPERRLLINQIKAHQFF 417
L +P R I+QI H FF
Sbjct: 256 LRASPRDRPSIDQILRHDFF 275
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 131 bits (330), Expect = 4e-30
Identities = 81/267 (30%), Positives = 133/267 (49%), Gaps = 9/267 (3%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ ++ G TLG+G++ V A S +AVKI++K + + E TL+ LK
Sbjct: 17 LGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLK 76
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I+ L+ ++ + ++E G+L + +G + E + Q+ID + + H
Sbjct: 77 HPH-IVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCH 135
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
KGV HRDLK EN+LLD +K+TDFG + L +D L + + G+ YV+
Sbjct: 136 SKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLH-------TTCGSPNYVA 188
Query: 332 PELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE+L N Y DIW+ G IL+ ++ G PF N + +QK+ K
Sbjct: 189 PEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGA 248
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
R ++K +L NP R+ + IKA ++F
Sbjct: 249 RTMIKRMLDPNPVTRITVVGIKASEWF 275
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 131 bits (329), Expect = 5e-30
Identities = 76/258 (29%), Positives = 140/258 (53%), Gaps = 14/258 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DFKF LG G + VLL+ S + +A+K L K ++ + +V+ + EK L +
Sbjct: 612 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVT 671
Query: 212 NTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV-NEKCTQYYAAQIIDALG 268
+ +++L+ FQ + F++EY+ GDL+ + H V +E +Y+A ++ L
Sbjct: 672 SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM--LHIHSDVFSEPRAIFYSACVVLGLQ 729
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
F+H+ +++RDLK +N+LLD + VK+ DFG + + + Y R+++F GT E
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK-------EGMGYG--DRTSTFCGTPE 780
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
+++PE+L D D W G +L++M+ G+ PF ++E F ++ + +
Sbjct: 781 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 840
Query: 389 TVRDLVKNILIKNPERRL 406
+++ +L +NPERRL
Sbjct: 841 EAIGIMRRLLRRNPERRL 858
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 131 bits (329), Expect = 5e-30
Identities = 76/258 (29%), Positives = 140/258 (53%), Gaps = 14/258 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DFKF LG G + VLL+ S + +A+K L K ++ + +V+ + EK L +
Sbjct: 612 LEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVT 671
Query: 212 NTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV-NEKCTQYYAAQIIDALG 268
+ +++L+ FQ + F++EY+ GDL+ + H V +E +Y+A ++ L
Sbjct: 672 SAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLM--LHIHSDVFSEPRAIFYSACVVLGLQ 729
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
F+H+ +++RDLK +N+LLD + VK+ DFG + + + Y R+++F GT E
Sbjct: 730 FLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK-------EGMGYG--DRTSTFCGTPE 780
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
+++PE+L D D W G +L++M+ G+ PF ++E F ++ + +
Sbjct: 781 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 840
Query: 389 TVRDLVKNILIKNPERRL 406
+++ +L +NPERRL
Sbjct: 841 EAIGIMRRLLRRNPERRL 858
>CE13844 [D] KOG0608 Warts/lats-like serine threonine kinases
Length = 908
Score = 131 bits (329), Expect = 5e-30
Identities = 74/235 (31%), Positives = 127/235 (53%), Gaps = 33/235 (14%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
+G G++ V L ++ K YA+K L K +I +++ +V E++ L ++ I+ L+
Sbjct: 508 IGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEA-DSPWIVRLF 566
Query: 221 FTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
F+FQD++ LYF++EY P GD+++L+ + G E ++Y A++ A+ ++H+ G IHRDL
Sbjct: 567 FSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDLARFYIAELACAIEYVHNVGFIHRDL 626
Query: 281 KPENILLDVDMKVKLTDFGTARLLDSTSE--------DDLKYDLLT-------------- 318
KP+NIL+D +KLTDFG L T + D + D +
Sbjct: 627 KPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKV 686
Query: 319 ----------RSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPF 363
++S VGT Y++PE++ + CD W+ G IL++M+ G+ PF
Sbjct: 687 LNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILYEMVFGRVPF 741
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 131 bits (329), Expect = 5e-30
Identities = 80/288 (27%), Positives = 145/288 (49%), Gaps = 30/288 (10%)
Query: 140 TGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKY 199
+G ++ ++ + ++K G TLG GS+ V +A + K A+KILN+ +K+K
Sbjct: 4 SGTGSRSGVESILPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNR------RKIKN 57
Query: 200 VNIEKNTLQRLKNTK-----GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEK 254
+ +E+ + +K + II LY + + +Y ++EY +G+L + + G + E
Sbjct: 58 MEMEEKVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQED 117
Query: 255 CTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKY 314
+ + QII + + H V+HRDLKPEN+LLD VK+ DFG + ++
Sbjct: 118 EARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIM---------- 167
Query: 315 DLLTRSNSFV----GTAEYVSPELLNDN-YVDFRCDIWAFGCILFQMIAGKPPFKANNEY 369
R F+ G+ Y +PE+++ Y D+W+ G IL+ ++ G PF N
Sbjct: 168 ----RDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIP 223
Query: 370 LTFQKVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
F+K+ + + RDL+ +L+ +P +R+ I +I+ H +F
Sbjct: 224 NLFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWF 271
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 131 bits (329), Expect = 5e-30
Identities = 78/290 (26%), Positives = 144/290 (48%), Gaps = 22/290 (7%)
Query: 138 KQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYL---IKQ 194
+ + K V G +K +TLG G+++ V LA + + ++ A+K+++K L +Q
Sbjct: 46 RSSPKFQSYVNGNGYGVYKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQ 105
Query: 195 KKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEK 254
K + VNI K N I+ L + E +LY ++EY G+L + + K+G + E+
Sbjct: 106 KLYREVNIMKKL-----NHPNIVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRER 160
Query: 255 CTQYYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKY 314
+ Q++ A+ + H K ++HRDLK EN+LLD MK+K+ DFG + + +
Sbjct: 161 DARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGFSTTFEPKAP----- 215
Query: 315 DLLTRSNSFVGTAEYVSPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQ 373
+F G+ Y +PEL Y D W+ G +L+ +++G PF N
Sbjct: 216 -----LETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRD 270
Query: 374 KVMKVQFAFTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFG 423
+V++ ++ + L++ L+ NP +R ++ + A ++ +N G
Sbjct: 271 RVLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRW---INMG 317
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 130 bits (328), Expect = 7e-30
Identities = 81/291 (27%), Positives = 146/291 (49%), Gaps = 28/291 (9%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK---QKKVKYVNIEKNTLQ 208
+ +++ T+G G+ + V LA I + ++ A+KI++K L QK + V I K
Sbjct: 56 VGNYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGL-- 113
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
N I+ L+ + E +LY ++EYA G++ + HG + EK + QI+ A+
Sbjct: 114 ---NHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVH 170
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
+ H K ++HRDLK EN+LLD + +K+ DFG + ++ L ++ ++F G+
Sbjct: 171 YCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN----------EFTLGSKLDTFCGSPP 220
Query: 329 YVSPELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
Y +PEL D DIW+ G IL+ +++G PF +N ++V++ ++
Sbjct: 221 YAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMS 280
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
+++ L+ NP +R + QI ++ +N G + EL PY
Sbjct: 281 TDCESILRRFLVLNPAKRCTLEQIMKDKW---INIG------YEGEELKPY 322
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 130 bits (328), Expect = 7e-30
Identities = 81/265 (30%), Positives = 143/265 (53%), Gaps = 12/265 (4%)
Query: 155 FKFGETLGDGSYSTVLLATSIESN-KKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
+ G+ LG G+++ V A +++ + A+K++ K+ L K +V E + ++RL++
Sbjct: 28 YDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRL-KDGLTAHVKREISVMRRLRHP 86
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
I+ L ++ +YF++E A G+L S + + E ++ Y Q+I A+ + H +
Sbjct: 87 H-IVLLSEVLATKTKIYFVMELAKGGELFSRVTSN-RFTESLSRKYFRQLISAVRYCHAR 144
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPE 333
GV HRDLKPEN+LLD + +K++DFG + + + D + + L GT YV+PE
Sbjct: 145 GVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTL-------CGTPAYVAPE 197
Query: 334 -LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRD 392
LL Y + DIW+ G +LF + AG PF+ N ++K+ K Q+ +R
Sbjct: 198 LLLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLPDWTSSDLRK 257
Query: 393 LVKNILIKNPERRLLINQIKAHQFF 417
L++ +L NPE R+ + +I +F
Sbjct: 258 LLRRLLEPNPELRITVEEILKDPWF 282
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 130 bits (327), Expect = 9e-30
Identities = 84/273 (30%), Positives = 135/273 (48%), Gaps = 18/273 (6%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK-NT 213
++ G LG G+Y+TV A IE+NK YA KI+NK+ + +KK +V E L+R+
Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMM--EKKQDFVKNEIAILKRVSYEH 88
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
I+ L F+ ++LY + E A G+L + GS E A+ ++HD
Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDN 148
Query: 274 GVIHRDLKPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
G++HRDLKPEN+L D + + + DFG L ED Y L+T GT EY+
Sbjct: 149 GIVHRDLKPENLLYRSKDPNSDLLIADFG----LSHFYEDSQYYMLMTA----CGTPEYM 200
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT----AGF 386
+PE+ D+WA G I + +++G PF ++ + ++ ++ F +G
Sbjct: 201 APEVFRRTGYGKPVDMWAIGVITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGI 260
Query: 387 PMTVRDLVKNILIKNPERRLLINQIKAHQFFAD 419
T +D +K L +P +RL H F ++
Sbjct: 261 SETAKDFIKKCLENDPSKRLTAADALKHPFLSE 293
>HsM4505191 [T] KOG0607 MAP kinase-interacting kinase and related
serine/threonine protein kinases
Length = 424
Score = 130 bits (327), Expect = 9e-30
Identities = 95/335 (28%), Positives = 165/335 (48%), Gaps = 53/335 (15%)
Query: 110 LPISESMQRRQKEWADRGAAMIVKDVPDKQTGKITKQVIKKGINDFKF-GETLGDGSYST 168
LPI++ +RR+K K+ G+ T + K + +K E LG+G+Y+
Sbjct: 19 LPIADGDRRRKK----------------KRRGRATDSLPGKFEDMYKLTSELLGEGAYAK 62
Query: 169 VLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYFTFQDESS 228
V A S+++ K+YAVKI+ K+ + +V E TL + + K I+ L F+D++
Sbjct: 63 VQGAVSLQNGKEYAVKIIEKQAGHSRSRVFR---EVETLYQCQGNKNILELIEFFEDDTR 119
Query: 229 LYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILLD 288
Y + E G +L+ ++K NE+ + AL F+H KG+ HRDLKPENIL +
Sbjct: 120 FYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCE 179
Query: 289 VDMK---VKLTDF--GTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELL-----NDN 338
K VK+ DF G+ L+++ +L T G+AEY++PE++
Sbjct: 180 SPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTP----CGSAEYMAPEVVEVFTDQAT 235
Query: 339 YVDFRCDIWAFGCILFQMIAGKPPFKAN---------------NEYLTFQKVMKVQFAFT 383
+ D RCD+W+ G +L+ M++G PPF + + F+ + + ++ F
Sbjct: 236 FYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFP 295
Query: 384 ----AGFPMTVRDLVKNILIKNPERRLLINQIKAH 414
A +DL+ +L+++ ++RL Q+ H
Sbjct: 296 DKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQH 330
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 130 bits (327), Expect = 9e-30
Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 15/270 (5%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
+ +TLG G ++ V LA + + +K AVK+++K L ++ +L
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHL--FQEVRCMKLVQHP 73
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS-VNEKCTQYYAAQIIDALGFMHDK 273
I+ LY ++ LY +LE GD+ + KH +NE + Y AQI+ A+ + H
Sbjct: 74 NIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKL 133
Query: 274 GVIHRDLKPENILL-DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
V+HRDLKPEN++ + VKLTDFG + K+ + + G+ Y +P
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSN----------KFQPGKKLTTSCGSLAYSAP 183
Query: 333 E-LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
E LL D Y DIW+ G ILF ++ G+PPF+ N+ T +M ++ + +
Sbjct: 184 EILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECK 243
Query: 392 DLVKNILIKNPERRLLINQIKAHQFFADVN 421
DL+ +L ++P+RR + +I+ H + V+
Sbjct: 244 DLITRMLQRDPKRRASLEEIENHPWLQGVD 273
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 130 bits (327), Expect = 9e-30
Identities = 90/369 (24%), Positives = 170/369 (45%), Gaps = 25/369 (6%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
++ G LG G ++ T+ + + A K++ K L+KQ + + E + L +
Sbjct: 38 YEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELGHIN 97
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
I+ L+ F+D ++Y LE L+ L ++ +V E +Y+ QI+D + ++HD
Sbjct: 98 -IVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLN 156
Query: 275 VIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPEL 334
+IHRD+K N+ L+ D+ VK+ DFG A ++ R + GT Y++PE+
Sbjct: 157 IIHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDE----------RKKTLCGTPNYIAPEV 206
Query: 335 LNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLV 394
LN F DIWA GCIL+ ++ G+PPF++ + T+ ++ + + L+
Sbjct: 207 LNKAGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLI 266
Query: 395 KNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDP-------PELGPYKVSARALQS 447
+ +L P RR Q++ FF +G + + P P+ G ++ S ++
Sbjct: 267 RKMLDPEPTRRPTAKQVQRDGFFK-----SGFMPTRLPVSCLTMVPKFGGHETSMME-EN 320
Query: 448 SVPKVASSPAINPIHEPVRQSSVSPKITPKNTTTAQRPNGDTTSTTTKRELDPRTQRILN 507
P+ + + P++ S++ P+ N +R T + D ++ +
Sbjct: 321 VAPRGVDARSQRPLNGRAGLSAL-PQHIVSNNADRERAQQQAAEATFREPEDAYLSQLFH 379
Query: 508 NVKKEISQR 516
V + QR
Sbjct: 380 QVAVLLEQR 388
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 130 bits (327), Expect = 9e-30
Identities = 82/280 (29%), Positives = 143/280 (50%), Gaps = 21/280 (7%)
Query: 151 GINDFKFG------ETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEK 204
G++D K ETLG G ++ V LA + + K AVK+++K L K ++
Sbjct: 10 GVSDGKIAGLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHL--FQE 67
Query: 205 NTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGS-VNEKCTQYYAAQI 263
+L ++ LY ++ LY +LE GDL + KH S ++E+ + Y QI
Sbjct: 68 VRCMKLVQHPNVVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQI 127
Query: 264 IDALGFMHDKGVIHRDLKPENILLDVDMK-VKLTDFGTARLLDSTSEDDLKYDLLTRSNS 322
+ A+ + H V+HRDLKPEN++ + VKLTDFG + K+ + +
Sbjct: 128 LRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSN----------KFLPGQKLET 177
Query: 323 FVGTAEYVSPE-LLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFA 381
F G+ Y +PE LL D+Y DIW+ G IL+ ++ G+ PF+ N+ T +M ++
Sbjct: 178 FCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYT 237
Query: 382 FTAGFPMTVRDLVKNILIKNPERRLLINQIKAHQFFADVN 421
+ RDL+ ++L+++P++R + +I + + ++
Sbjct: 238 VPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKPID 277
>7292679 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 560
Score = 130 bits (327), Expect = 9e-30
Identities = 81/275 (29%), Positives = 139/275 (50%), Gaps = 26/275 (9%)
Query: 159 ETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQR---LKNTKG 215
E LG G STV E+ K++A KI++ + + ++ + T Q L+ G
Sbjct: 27 EILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNPYHMLEATRQEISILRQVMG 86
Query: 216 ---IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
II L F+ ++ ++ + E P G+L + +++EK T+ QI + + ++H
Sbjct: 87 HPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTIMRQIFEGVEYIHA 146
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSP 332
K ++HRDLKPENILLD + VK+TDFG A+ L + + GT Y++P
Sbjct: 147 KSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGE----------KLTNLCGTPGYLAP 196
Query: 333 ELLNDNYVD------FRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFT--- 383
E L N + DIWA G I+F ++ G PPF + + + +M+ +++FT
Sbjct: 197 ETLKCNMFEGSPGYSQEVDIWACGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPE 256
Query: 384 -AGFPMTVRDLVKNILIKNPERRLLINQIKAHQFF 417
A +DL++ L+ +P +R+ + ++ H FF
Sbjct: 257 WADISEDPKDLIRKCLVVDPSQRITVKEVLRHPFF 291
>Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 2092
Score = 130 bits (326), Expect = 1e-29
Identities = 81/287 (28%), Positives = 148/287 (51%), Gaps = 19/287 (6%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF+ + + +G+Y V ES +++A+K +NK+ LI + +++ +E++ L +N
Sbjct: 37 SDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAEN 96
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
++S+Y +F+ L ++EY GD +LM+ G + + Y A+ + AL ++H+
Sbjct: 97 PF-VVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHN 155
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFG---------TARLLDSTSEDDLKYDLLTRSNSF 323
G++HRDLKP+N+L+ +KLTDFG T L + E D + L
Sbjct: 156 YGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFL---DKQV 212
Query: 324 VGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAF- 382
GT EY++PE++ D WA G IL++ + G PF + F +V+ + +
Sbjct: 213 CGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWP 272
Query: 383 --TAGFPMTVRDLVKNILIKNPERRLLIN---QIKAHQFFADVNFGN 424
P +DL+ +L +NP RL ++K H+FF +++ +
Sbjct: 273 EKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNS 319
>Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1734
Score = 130 bits (326), Expect = 1e-29
Identities = 79/284 (27%), Positives = 146/284 (50%), Gaps = 19/284 (6%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF+ + + +G+Y V L + +++A+K +NK+ LI + +++ +E++ L +N
Sbjct: 511 DFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENP 570
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDK 273
++S++ +F + L ++EY GD +L++ G++ + Y A+ + AL ++H+
Sbjct: 571 F-VVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNY 629
Query: 274 GVIHRDLKPENILLDVDMKVKLTDFG---------TARLLDSTSEDDLKYDLLTRSNSFV 324
G++HRDLKP+N+L+ +KLTDFG T L + E D + L
Sbjct: 630 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFL---DKQVC 686
Query: 325 GTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTA 384
GT EY++PE++ D WA G IL++ + G PF + F +V+ + +
Sbjct: 687 GTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPE 746
Query: 385 G---FPMTVRDLVKNILIKNPERRL---LINQIKAHQFFADVNF 422
G P +DL +L +NP RL ++K H FF +++
Sbjct: 747 GDEALPPDAQDLTSKLLHQNPLERLGTGSAYEVKQHPFFTGLDW 790
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 130 bits (326), Expect = 1e-29
Identities = 85/269 (31%), Positives = 135/269 (49%), Gaps = 16/269 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I + G TLG G++ V + + K AVKILN++ K K + V + +Q LK
Sbjct: 25 IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQ---KIKSLDVVGKIRREIQNLK 81
Query: 212 NTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGF 269
+ II LY S ++ ++EY G+L + KHG + E + + QII + +
Sbjct: 82 LFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDY 141
Query: 270 MHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEY 329
H ++HRDLKPEN+LLD +M VK+ DFG + ++ L + L S G+ Y
Sbjct: 142 CHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMM-------LDGEFLRTS---CGSPNY 191
Query: 330 VSPELLNDN-YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
+PE+++ Y DIW+ G IL+ ++ G PF + F+K+ F
Sbjct: 192 AAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNK 251
Query: 389 TVRDLVKNILIKNPERRLLINQIKAHQFF 417
V +LV +L +P +R I +IK H++F
Sbjct: 252 QVVNLVCQMLQVDPLKRANIEEIKKHEWF 280
>Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1139
Score = 129 bits (325), Expect = 2e-29
Identities = 76/277 (27%), Positives = 152/277 (54%), Gaps = 13/277 (4%)
Query: 153 NDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKN 212
+DF+ + + +G+Y V L ++ +++A+K +NK+ LI + +++ V +E++ L +N
Sbjct: 195 SDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAEN 254
Query: 213 TKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHD 272
++S++ +F+ L ++EY GD +L++ G + + Y A+ + AL ++H+
Sbjct: 255 PF-VVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHN 313
Query: 273 KGVIHRDLKPENILLDVDMKVKLTDFGTARL-LDSTSEDDLKYDLLTRSNSFV-----GT 326
G++HRDLKP+N+L+ +KLTDFG +++ L S + + + + + F+ GT
Sbjct: 314 YGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGT 373
Query: 327 AEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG- 385
EY++PE++ D WA G +L++ + G PF + F +V+ + + G
Sbjct: 374 PEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGD 433
Query: 386 --FPMTVRDLVKNILIKNPERRL---LINQIKAHQFF 417
P +DL+ +L ++P RL +++K H FF
Sbjct: 434 EALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFF 470
>At4g04720 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 531
Score = 129 bits (325), Expect = 2e-29
Identities = 85/286 (29%), Positives = 142/286 (48%), Gaps = 22/286 (7%)
Query: 136 PDKQTGKITKQVIKKGINDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQK 195
PD GK + + K + G+ LG G + + I + YA K + K LI ++
Sbjct: 65 PDTILGKPFEDIRKF----YSLGKELGRGQFGITYMCKEIGTGNTYACKSILKRKLISKQ 120
Query: 196 KVKYVNIEKNTLQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKC 255
+ V E +Q L I+ + ++D S++ ++E G+L + G +E+
Sbjct: 121 DKEDVKREIQIMQYLSGQPNIVEIKGAYEDRQSIHLVMELCAGGELFDRIIAQGHYSERA 180
Query: 256 TQYYAAQIIDALGFMHDKGVIHRDLKPENILL---DVDMKVKLTDFGTARLLDSTSEDDL 312
I++ + H GV+HRDLKPEN LL + + +K TDFG + ++ E +
Sbjct: 181 AAGIIRSIVNVVQICHFMGVVHRDLKPENFLLSSKEENAMLKATDFGLSVFIE---EGKV 237
Query: 313 KYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTF 372
D+ VG+A YV+PE+L +Y DIW+ G IL+ +++G PPF A NE F
Sbjct: 238 YRDI-------VGSAYYVAPEVLRRSY-GKEIDIWSAGVILYILLSGVPPFWAENEKGIF 289
Query: 373 QKVMKVQFAFTA----GFPMTVRDLVKNILIKNPERRLLINQIKAH 414
+V+K + F + + +DLV+ +L K+P+RR+ Q+ H
Sbjct: 290 DEVIKGEIDFVSEPWPSISESAKDLVRKMLTKDPKRRITAAQVLEH 335
>Hs4506529 [T] KOG0986 G protein-coupled receptor kinase
Length = 563
Score = 129 bits (324), Expect = 2e-29
Identities = 83/276 (30%), Positives = 144/276 (52%), Gaps = 25/276 (9%)
Query: 161 LGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLY 220
LG G + V + K YA K LNK+ L K+K + +EK L ++ +++ I+SL
Sbjct: 196 LGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKV-HSRFIVSLA 254
Query: 221 FTFQDESSLYFLLEYAPNGDL----LSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVI 276
+ F+ ++ L ++ GD+ ++ ++ E +Y AQII L +H + ++
Sbjct: 255 YAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGLEHLHQRRIV 314
Query: 277 HRDLKPENILLDVDMKVKLTDFGTA-RLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELL 335
+RDLKPEN+LLD D V+++D G A LLD S ++ + GT +++PELL
Sbjct: 315 YRDLKPENVLLDNDGNVRISDLGLAVELLDGQS----------KTKGYAGTPGFMAPELL 364
Query: 336 NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQ----KVMKVQFAFTAGFPMTVR 391
DF D +A G L++MIA + PF+A E + + +++ + F +
Sbjct: 365 QGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFSQASK 424
Query: 392 DLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
D + +L K+PE+RL ++++AH F D+N+
Sbjct: 425 DFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNW 460
>ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 322
Score = 129 bits (324), Expect = 2e-29
Identities = 84/286 (29%), Positives = 141/286 (48%), Gaps = 16/286 (5%)
Query: 152 INDFKFGETLGDGSYSTV-LLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRL 210
I DF+F + +G G++ V L+ +A+K+L+ +++Q+ + E + L+R+
Sbjct: 4 IQDFEFVKVVGVGAFGKVHLVRLKSSPTSVFAMKMLDFGEILRQRLADQLENEISILKRI 63
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
+ LY T + ++EY G+L ++K G +E+ ++YAA+II AL F+
Sbjct: 64 YGCPFVAKLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFI 123
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H +G+++RDLKPENIL+ +KL DFG S E + Y GT EY+
Sbjct: 124 HGRGILYRDLKPENILITSTGHIKLIDFGF-----SVYESENIY-------MISGTPEYM 171
Query: 331 SPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
SPE L D W G ++++M+ G PPF ++ + K+++ F
Sbjct: 172 SPEKLRSEDDGRASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVA 231
Query: 391 RDLVKNILIKNPERRL---LINQIKAHQFFADVNFGNGSVWDKDPP 433
R L+ +L KN RL I +I H FF +++ +PP
Sbjct: 232 RCLITGLLDKNRATRLGTKGICEIMGHPFFKGIDWHEVESRRIEPP 277
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 129 bits (324), Expect = 2e-29
Identities = 80/265 (30%), Positives = 134/265 (50%), Gaps = 15/265 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKN-TLQRL 210
+ ++ +TLG G V L KK A+KI+N+E L + +K +E+ + +L
Sbjct: 15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMK---VEREIAIMKL 71
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
+ ++ L ++++ LY +LE+ G+L + K G + K + + QII AL F
Sbjct: 72 IDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 131
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H + HRDLKPEN+LLD +K+ DFG A L + S +L S G+ Y
Sbjct: 132 HSHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGS-------MLETS---CGSPHYA 181
Query: 331 SPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
PE++ + Y + D+W+ G IL+ ++ G PF +N +KV + F P
Sbjct: 182 CPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPD 241
Query: 390 VRDLVKNILIKNPERRLLINQIKAH 414
+ L++ ++ NP+RRL + +I H
Sbjct: 242 CQSLLRGMIEVNPDRRLTLAEINRH 266
>Hs7019489 [T] KOG0694 Serine/threonine protein kinase
Length = 889
Score = 129 bits (323), Expect = 3e-29
Identities = 83/279 (29%), Positives = 143/279 (50%), Gaps = 19/279 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ DF+ LG G + VLL + K YA+K L K+ ++ + +++ + EK L+ +
Sbjct: 556 LQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVG 615
Query: 212 NTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV-NEKCTQYYAAQIIDALG 268
T ++SL FQ S F+ E+ P GDL+ M+ H V E ++Y A ++ L
Sbjct: 616 CTGHPFLLSLLVCFQTSSHARFVTEFVPGGDLM--MQIHEDVFPEPQARFYVACVVLGLQ 673
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
F+H+K +I+RDLK +N+LLD +K+ DFG + + D R+++F GT E
Sbjct: 674 FLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCK--EGIGFGD-------RTSTFCGTPE 724
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
+++PE+L D WA G +L++M+ G+ PF + E F ++ + + +
Sbjct: 725 FLAPEVLTQEAYTQAVDWWALGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSV 784
Query: 389 TVRDLVKNILIKNPERRL-----LINQIKAHQFFADVNF 422
+ ++ +L K PE+RL +IK FF N+
Sbjct: 785 QGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNW 823
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 129 bits (323), Expect = 3e-29
Identities = 80/268 (29%), Positives = 136/268 (49%), Gaps = 15/268 (5%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKN-TLQRL 210
+ ++ +TLG G V L + +K A+KI+N+E L + +K +E+ + +L
Sbjct: 48 VGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK---VEREIAILKL 104
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
++ L+ ++++ LY +LE+ G+L + K G + K + + QI+ AL F
Sbjct: 105 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFC 164
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H + HRDLKPEN+LLD +++ DFG A L S LL S G+ Y
Sbjct: 165 HSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS-------LLETS---CGSPHYA 214
Query: 331 SPELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
PE++ + Y R D+W+ G ILF ++ G PF +N +KV + F P
Sbjct: 215 CPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPD 274
Query: 390 VRDLVKNILIKNPERRLLINQIKAHQFF 417
+ L++ ++ PE+RL + QI+ H ++
Sbjct: 275 CQSLLRGMIEVEPEKRLSLEQIQKHPWY 302
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 129 bits (323), Expect = 3e-29
Identities = 79/262 (30%), Positives = 135/262 (51%), Gaps = 21/262 (8%)
Query: 160 TLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKN----TLQRLKNTKG 215
TLG G+++ V L + + A+KI++K L VN+EK + ++ +
Sbjct: 25 TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQL------DAVNLEKIYREVQIMKMLDHPH 78
Query: 216 IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGV 275
II LY + +S LY + EYA NG++ + HG +NE + QI+ A+ + H + +
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138
Query: 276 IHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELL 335
+HRDLK EN+LLD +M +K+ DFG S +LL ++ G+ Y +PE+
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSG-------ELLA---TWCGSPPYAAPEVF 188
Query: 336 -NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLV 394
Y + DIW+ G +L+ ++ G PF + Q+V++ +F L+
Sbjct: 189 EGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLI 248
Query: 395 KNILIKNPERRLLINQIKAHQF 416
+ +L+ +P +RL I QIK H++
Sbjct: 249 RRMLVLDPSKRLTIAQIKEHKW 270
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 129 bits (323), Expect = 3e-29
Identities = 83/291 (28%), Positives = 148/291 (50%), Gaps = 28/291 (9%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIK---QKKVKYVNIEKNTLQ 208
I +K +T+G G+++ V LA + + K+ A+KI++K L QK + V I K
Sbjct: 148 IGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMK---- 203
Query: 209 RLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALG 268
+ + I+ L+ + E +LY ++EYA G++ + HG + EK + QI+ A+
Sbjct: 204 -MLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQ 262
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
+ H K +IHRDLK EN+LLD ++ +K+ DFG + S+ D +F G+
Sbjct: 263 YCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLD----------TFCGSPP 312
Query: 329 YVSPELLNDNYVDF-RCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFP 387
Y +PEL D D+W+ G IL+ +++G PF + ++V++ ++
Sbjct: 313 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMS 372
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPY 438
+L++ L+ NP +R + I ++ +N G +++D EL PY
Sbjct: 373 TDCENLLRKFLVLNPAKRASLETIMGDKW---MNMG----FEED--ELKPY 414
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 129 bits (323), Expect = 3e-29
Identities = 80/263 (30%), Positives = 131/263 (49%), Gaps = 14/263 (5%)
Query: 154 DFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNT 213
DF+ G LG G + V LA S+ A+K++ KE L K + V E RLK+
Sbjct: 52 DFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHP 111
Query: 214 KGIISLYFTFQDESSLYFLLEYAPNGDLLSLMR--KHGSVNEKCTQYYAAQIIDALGFMH 271
I+ L F DES +Y LE A G+L +R + +E + Y Q+ +AL + H
Sbjct: 112 H-ILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCH 170
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
VIHRDLKPENILL +KL DFG + + + + GT +Y+
Sbjct: 171 LNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNN-----------KRRTLCGTLDYLP 219
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVR 391
PE+++ N D D W G + ++ + G PPF++N+ T+ K+ +++ ++ + +
Sbjct: 220 PEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCK 279
Query: 392 DLVKNILIKNPERRLLINQIKAH 414
+L+ +L K + R+ + + H
Sbjct: 280 ELIGGLLRKESKGRITLVDVMTH 302
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 128 bits (322), Expect = 4e-29
Identities = 89/282 (31%), Positives = 143/282 (50%), Gaps = 30/282 (10%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNT----- 206
I +K GETLG GS V LA + + ++ AVK+++K + V +I +T
Sbjct: 16 IGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKA-VFNTGNVSGTSIVGSTTPDAL 74
Query: 207 ---------LQRLKNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ 257
+ +L N ++ LY ++ + LY +LEYA G+L +L+ + G + E
Sbjct: 75 PYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAI 134
Query: 258 YYAAQIIDALGFMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLL 317
+ QII + + H G++HRDLKPEN+LLD +K+ DFG A L + + LL
Sbjct: 135 RFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAAL-------ETEGKLL 187
Query: 318 TRSNSFVGTAEYVSPELLND-NYVDFRCDIWAFGCILFQMIAGKPPF--KANNEYLTFQK 374
S G+ Y +PE+++ Y F D+W+ G ILF ++ G+ PF + N K
Sbjct: 188 ETS---CGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLK 244
Query: 375 VMKVQFAFTAGFPMT--VRDLVKNILIKNPERRLLINQIKAH 414
V K +F + ++ +DL++ IL +PERR+ I H
Sbjct: 245 VQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKH 286
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 128 bits (322), Expect = 4e-29
Identities = 71/284 (25%), Positives = 141/284 (49%), Gaps = 18/284 (6%)
Query: 155 FKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTK 214
+ GE LG G + + + + + ++ A K ++K+ L+ Q +K + +E + +L
Sbjct: 44 YVLGEQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLAGHP 103
Query: 215 GIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKG 274
+++L ++++ S++ ++E G+L + K+G +E + ++ + F HD G
Sbjct: 104 NVVNLKAVYEEKDSVHLVMELCAGGELFHKLEKYGRYSEVRARVLFKHLMQVVKFCHDSG 163
Query: 275 VIHRDLKPENIL---LDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
++HRDLKPENIL + +KL DFG A + + + VG+ Y++
Sbjct: 164 IVHRDLKPENILMATMSSSSPIKLADFGLATYIKPGE----------KLSGTVGSPFYIA 213
Query: 332 PELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTA----GFP 387
PE+L Y + D+W+ G IL+ +++G PPF + F V F+A
Sbjct: 214 PEVLAGGY-NQAADVWSAGVILYILLSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNIT 272
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKD 431
+DL++ +L +P +RL +++ AH + ++ +D+D
Sbjct: 273 SYAKDLIRGMLCVDPSQRLSADEVLAHSWMEQLSESGQEQYDQD 316
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 128 bits (322), Expect = 4e-29
Identities = 91/310 (29%), Positives = 156/310 (49%), Gaps = 37/310 (11%)
Query: 133 KDVPDKQTGKITKQVIKKGINDFKFG--ETLGDGSYSTVLLATSIES-NKKYAVKILNKE 189
KD K K K++ K+ + K+ LG G++S V LA S +S + +AVKI++K+
Sbjct: 7 KDSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKK 66
Query: 190 YLIKQKKVKYVNIEKNTLQR----------LKNTK----GIISLYFTFQDESSLYFLLEY 235
L + K + + E L+R L T+ I+ L T++D+S +Y ++E
Sbjct: 67 AL--KGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMEL 124
Query: 236 APNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDLKPENILL---DVDMK 292
G+L + + GS EK + QI++A+ +MH++GV+HRDLKPEN+L D D K
Sbjct: 125 VTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSK 184
Query: 293 VKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLNDNYVDFRCDIWAFGCI 352
+ ++DFG +++ DS + GT YV+PE+L D+W+ G I
Sbjct: 185 IMISDFGLSKMEDSGI-----------MATACGTPGYVAPEVLAQKPYGKAVDVWSIGVI 233
Query: 353 LFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGF----PMTVRDLVKNILIKNPERRLLI 408
+ ++ G PPF N+ F +++K F F + + + + +KN++ E+R
Sbjct: 234 SYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTC 293
Query: 409 NQIKAHQFFA 418
Q H + +
Sbjct: 294 KQALGHAWIS 303
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 128 bits (321), Expect = 5e-29
Identities = 70/260 (26%), Positives = 136/260 (51%), Gaps = 10/260 (3%)
Query: 158 GETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGII 217
G LG G ++ + ++ + +A KI+ K L+K + + +++E + + L + + ++
Sbjct: 56 GRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAH-QHVV 114
Query: 218 SLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIH 277
+ F+D ++ +LE LL L ++ ++ E +YY QI+ ++H VIH
Sbjct: 115 GFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIH 174
Query: 278 RDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLND 337
RDLK N+ L+ D++VK+ DFG A ++ E R + GT Y++PE+L+
Sbjct: 175 RDLKLGNLFLNEDLEVKIGDFGLATKVEYDGE---------RKKTLCGTPNYIAPEVLSK 225
Query: 338 NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTVRDLVKNI 397
F D+W+ GCI++ ++ GKPPF+ + T+ ++ K +++ L++ +
Sbjct: 226 KGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKM 285
Query: 398 LIKNPERRLLINQIKAHQFF 417
L +P R IN++ +FF
Sbjct: 286 LQTDPTARPTINELLNDEFF 305
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 127 bits (320), Expect = 6e-29
Identities = 78/267 (29%), Positives = 133/267 (49%), Gaps = 12/267 (4%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
I +F ET+G G++ V T I++ A+KILN+ + V E + LQ+L
Sbjct: 21 IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLT 80
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ I L+ S ++ ++E G+L S + + G++ + ++ Y QII + + H
Sbjct: 81 HPH-ITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCH 139
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
+ ++HRDLKPEN+LLD + +K+ DFG + + DLL+ + G+ Y +
Sbjct: 140 NHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDG-------DLLSTA---CGSPNYAA 189
Query: 332 PELL-NDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PEL+ N YV D+W+ G IL+ M+ G PF N F K+ ++
Sbjct: 190 PELISNKLYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQA 249
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF 417
DL+ +L +P +R + +I H +F
Sbjct: 250 ADLISTMLQVDPVKRADVKRIVNHSWF 276
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 127 bits (319), Expect = 8e-29
Identities = 85/294 (28%), Positives = 142/294 (47%), Gaps = 18/294 (6%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKI-LNKEYLIKQKKVKYVNIEKNTLQRL 210
+ ++ +G+GS+ V LA + +N K +K K+ +I +++ + R
Sbjct: 28 VGTYRIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAIILAREIHH--------HRR 79
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFM 270
I LY E +Y +EY PNG+L + + ++EK T Q+ A+ ++
Sbjct: 80 LLHPNITRLYEVVCTEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYL 139
Query: 271 HDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYV 330
H +G +HRDLK ENI LD VKL DFG +R D + T N+ GT Y
Sbjct: 140 HRQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRR--------TFMNTRCGTVAYC 191
Query: 331 SPELLNDN-YVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMT 389
+PEL+ + Y+ DIW+ G I++ ++ G+ PF ++ LT QK++ +
Sbjct: 192 APELVQGHKYIGECVDIWSLGIIMYALLIGRLPFDEDDVSLTEQKIINECPQYPETLSKN 251
Query: 390 VRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSAR 443
L+K++L K+ R I+QI +H +F + + + S+ D P KV R
Sbjct: 252 SSSLLKSLLCKDYRLRPSIDQIISHPYFKENGYHSSSIRDPRPSSKAEEKVRKR 305
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 127 bits (319), Expect = 8e-29
Identities = 100/351 (28%), Positives = 166/351 (46%), Gaps = 29/351 (8%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ + G TLG G+ + V L ++N+K A+K++ + L + K + E L++L
Sbjct: 20 VGPWLLGRTLGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLH 79
Query: 212 NTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQYYAAQIIDALGFMH 271
+ II+LY F+ LEY DL S++ KH ++E T+ QI+ A+ + H
Sbjct: 80 HPN-IITLYQVFRVPKYTVLALEYMDT-DLHSMVVKHNRLDECTTRKIFRQIVHAIDYCH 137
Query: 272 DKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVS 331
V HRDLK ENILL+ D+ VKLTDFG + + L L+ S GT Y +
Sbjct: 138 LHRVAHRDLKLENILLNKDLVVKLTDFGLSNFM-------LDGSFLSTS---CGTPHYAA 187
Query: 332 PELLNDNYVD-FRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPMTV 390
PE++ Y D D+W G +L+ M+ G+ PF+ +V K + + +
Sbjct: 188 PEVIQGRYYDGCDVDVWGCGILLYLMLVGEFPFEDVTISNVLSRVCKGIYTIPSFVSSSA 247
Query: 391 RDLVKNILIKNPERRLLINQIKAHQFF-ADVNFGNGSVWDKDPPELGPYKVSARALQSSV 449
DL++ +L+ P R+ + +I H +F AD+ + P + R++ S
Sbjct: 248 SDLIRQMLMVLPTSRIKVAEIMQHPWFIADL-----PTHSRLPSRTSSFSSKHRSVTFSP 302
Query: 450 PKVA---------SSPAINPIHEPVRQSSVSPKITPKNTTTAQRPNGDTTS 491
P +A S ++ I +P S++SP P + + + PN D S
Sbjct: 303 PDLAILFDPSITSPSSSVGQIPQPTDHSALSPS-KPMSISGTESPNPDPAS 352
>At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 606
Score = 127 bits (319), Expect = 8e-29
Identities = 94/328 (28%), Positives = 155/328 (46%), Gaps = 29/328 (8%)
Query: 112 ISESMQRRQ--KEWADRGAAMIVKDVPDKQTGKITKQVIKKGIND-----FKFGETLGDG 164
I +++RR+ KE A G + +VP ++ + + G + + GE +G G
Sbjct: 100 IRAALRRRKGKKEAALSGVTQLTTEVPQREEEEEVGLDKRFGFSKEFHSRVELGEEIGRG 159
Query: 165 SYSTVLLATSIESNKK---YAVKILNKEYLIKQKKVKYVNIEKNTLQRLKNTKGIISLYF 221
+ A + K AVKI+ K + ++ V E LQ L K ++ Y
Sbjct: 160 HFGYTCSAKFKKGELKGQVVAVKIIPKSKMTTAIAIEDVRREVKILQALSGHKNLVQFYD 219
Query: 222 TFQDESSLYFLLEYAPNGDLLS-LMRKHGSVNEKCTQYYAAQIIDALGFMHDKGVIHRDL 280
F+D +++Y +E G+LL ++ + G +E + QI++ + F H +GV+HRDL
Sbjct: 220 AFEDNANVYIAMELCEGGELLDRILARGGKYSENDAKPVIIQILNVVAFCHFQGVVHRDL 279
Query: 281 KPENILL---DVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAEYVSPELLND 337
KPEN L + + ++K DFG L D D+ R N VG+A YV+PE+L+
Sbjct: 280 KPENFLYTSKEENSQLKAIDFG---LSDFVRPDE-------RLNDIVGSAYYVAPEVLHR 329
Query: 338 NYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAG----FPMTVRDL 393
+Y D+W+ G I + ++ G PF A E F+ V+K +F +D
Sbjct: 330 SYTT-EADVWSIGVIAYILLCGSRPFWARTESGIFRAVLKADPSFDEPPWPFLSSDAKDF 388
Query: 394 VKNILIKNPERRLLINQIKAHQFFADVN 421
VK +L K+P RR+ +Q H + N
Sbjct: 389 VKRLLFKDPRRRMSASQALMHPWIRAYN 416
>CE18699 [T] KOG0694 Serine/threonine protein kinase
Length = 1018
Score = 126 bits (317), Expect = 1e-28
Identities = 78/287 (27%), Positives = 152/287 (52%), Gaps = 23/287 (8%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQKKVKYVNIEKNTLQRLK 211
+ F+ LG G + V+L+ ++ YA+K+L K ++ + +V+ + +EK +
Sbjct: 687 VEQFRLISVLGRGHFGKVILSQHNPTSNYYALKVLKKGDILGRDEVESLMVEKRIFEVSS 746
Query: 212 NTKG--IISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSVNEKCTQ-YYAAQIIDALG 268
+ +++L FQ ++F +EY+ GDL+ + H V ++ +YAA ++ L
Sbjct: 747 RARHPFLVNLNGCFQTNEHVFFCMEYSMGGDLMRHI--HDDVFDEVRGCFYAACVVLGLD 804
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
F+H +I+RD+K +N+LLD + VK+ DFG + E+ +D ++++F GT E
Sbjct: 805 FLHKHNIIYRDIKLDNLLLDREGYVKIADFGLCK------ENMGPFD---KTSTFCGTPE 855
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFAFTAGFPM 388
+++PE+L+D+ D W G ++F+M+ G+PPF ++E F ++ + +
Sbjct: 856 FLAPEVLSDSSYTRAIDWWGLGVLIFEMLVGEPPFSGDDEEEIFDSIISEDVRYPRYLSV 915
Query: 389 TVRDLVKNILIKNPERRLLINQ-----IKAHQFFADVNFGNGSVWDK 430
+++ +L K PE+RL + IK +FF +++ WDK
Sbjct: 916 ESIAIMRRLLRKVPEKRLGYGERDAEDIKIQRFFRHISW----EWDK 958
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 126 bits (317), Expect = 1e-28
Identities = 99/390 (25%), Positives = 182/390 (46%), Gaps = 48/390 (12%)
Query: 152 INDFKFGETLGDGSYSTVLLATSIESNKKYAVKILNKEYLIKQ-KKVKYVNIEKNTLQRL 210
++D++ E +G G++ + L +KY VK K L KQ ++ K I++ +L
Sbjct: 12 MDDYEVVEQIGRGAFGSAFLVIHKSERRKYVVK---KIRLAKQTERCKLAAIQEMSLISK 68
Query: 211 KNTKGIISLYFTFQDESSLYFLLEYAPNGDLLSLMRKHGSV--NEKCTQYYAAQIIDALG 268
+ I+ ++ ++ + + Y GD+ +++K V +E+ + Q++ A+
Sbjct: 69 LKSPYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAID 128
Query: 269 FMHDKGVIHRDLKPENILLDVDMKVKLTDFGTARLLDSTSEDDLKYDLLTRSNSFVGTAE 328
++H+ V+HRDLK NI L + +V+L DFG A+LL +DDL ++S VGT
Sbjct: 129 YLHNNRVLHRDLKCSNIFLTKENEVRLGDFGLAKLL---GKDDL-------ASSMVGTPN 178
Query: 329 YVSPELLNDNYVDFRCDIWAFGCILFQMIAGKPPFKANNEYLTFQKVMKVQFA-FTAGFP 387
Y+ PELL D ++ DIW+ GC +F++ A +P FKA + K+ + + +
Sbjct: 179 YMCPELLADIPYGYKSDIWSLGCCMFEVAAHQPAFKAPDMAALINKINRSSLSPLPVMYS 238
Query: 388 MTVRDLVKNILIKNPERRLLINQIKAHQFFADVNFGNGSVWDKDPPELGPYKVSARALQS 447
+++ L+K++L KNPE R ++ H P L PY + L
Sbjct: 239 SSLKRLIKSMLRKNPEHRPTAAELLRH------------------PHLQPYLAQCQNLSP 280
Query: 448 SVPKVASSPAINPIHE-----PVRQSSVSPKITPKNTTTAQRPNGDTTSTTTKRELDPRT 502
V S N P +S+ +P + + ++ N DT+S++ +E ++
Sbjct: 281 VFKPVVSKSEHNTNENRTGLPPKTKSAKTPIKHNQESEETEKKNKDTSSSSKDKERPAKS 340
Query: 503 QR--------ILNNVKKEISQRNHRRAALK 524
Q +L +K+ + R AL+
Sbjct: 341 QEMSVISTLTLLREFQKKSPKSEERAEALE 370
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,908,657
Number of Sequences: 60738
Number of extensions: 2217556
Number of successful extensions: 13907
Number of sequences better than 1.0e-05: 1780
Number of HSP's better than 0.0 without gapping: 553
Number of HSP's successfully gapped in prelim test: 1227
Number of HSP's that attempted gapping in prelim test: 9721
Number of HSP's gapped (non-prelim): 2397
length of query: 925
length of database: 30,389,216
effective HSP length: 116
effective length of query: 809
effective length of database: 23,343,608
effective search space: 18884978872
effective search space used: 18884978872
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)