ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3062 good DZ KOG1727 Cell cycle control, cell division, chromosome partitioning Microtubule-binding protein (translationally controlled tumor protein)
r_klactIII3062 good DZ KOG1727 Cytoskeleton Microtubule-binding protein (translationally controlled tumor protein)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3062 1079048 1079548 167
(167 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL056c [DZ] KOG1727 Microtubule-binding protein (translationall... 270 7e-73
SPAC1F12.02c [DZ] KOG1727 Microtubule-binding protein (translati... 211 4e-55
Hs4507669 [DZ] KOG1727 Microtubule-binding protein (translationa... 139 2e-33
7299413 [DZ] KOG1727 Microtubule-binding protein (translationall... 130 8e-31
At3g16640 [DZ] KOG1727 Microtubule-binding protein (translationa... 112 2e-25
Hs17467871 [DZ] KOG1727 Microtubule-binding protein (translation... 105 4e-23
Hs11056002 [DZ] KOG1727 Microtubule-binding protein (translation... 103 1e-22
At3g05540 [DZ] KOG1727 Microtubule-binding protein (translationa... 89 2e-18
Hs8923032_2 [DZ] KOG1727 Microtubule-binding protein (translatio... 77 8e-15
CE09656 [DZ] KOG1727 Microtubule-binding protein (translationall... 73 2e-13
Hs17485897 [DZ] KOG1727 Microtubule-binding protein (translation... 65 3e-11
Hs17460089 [DZ] KOG1727 Microtubule-binding protein (translation... 55 6e-08
Hs22052803_2 [DZ] KOG1727 Microtubule-binding protein (translati... 55 6e-08
Hs17462926 [DZ] KOG1727 Microtubule-binding protein (translation... 54 1e-07
>YKL056c [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 167
Score = 270 bits (690), Expect = 7e-73
Identities = 132/167 (79%), Positives = 140/167 (83%)
Query: 1 MIIYTDIISGDELLSDAYDLKLVDGVIYEADCDMVKVGGDNIDIGANPSAXXXXXXXXXX 60
MIIY DI S DELLSDAYD KLVD VIYEADC MV VGGDNIDIGANPSA
Sbjct: 1 MIIYKDIFSNDELLSDAYDAKLVDDVIYEADCAMVNVGGDNIDIGANPSAEGGDDDVEEG 60
Query: 61 XXLVNNVVHSFRLQQTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAYVKKV 120
+VNNVVHSFRLQQTAFDKKSFLTYIKGYMK +K +LQE+NP+EV FEKGAQ YVKKV
Sbjct: 61 AEMVNNVVHSFRLQQTAFDKKSFLTYIKGYMKAVKAKLQETNPEEVPKFEKGAQTYVKKV 120
Query: 121 IGSFKDWEFFTGESMDPDGMLVLLNYREDGTTPFVAIWKHGVKAEKI 167
IGSFKDWEFFTGESMDPD M+V+LNYREDGTTPFVAIWKHG+ EKI
Sbjct: 121 IGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKHGIVEEKI 167
>SPAC1F12.02c [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 168
Score = 211 bits (537), Expect = 4e-55
Identities = 102/168 (60%), Positives = 130/168 (76%), Gaps = 3/168 (1%)
Query: 1 MIIYTDIISGDELLSDAYDLKLVDGVIYEADCDMVKV--GGDNIDIGANPSAXXXXXXXX 58
M++Y D+ISGDEL+SDAYDLK VD ++YEADC MV V GGD +DIGANPSA
Sbjct: 1 MLLYKDVISGDELVSDAYDLKEVDDIVYEADCQMVTVKQGGD-VDIGANPSAEDAEENAE 59
Query: 59 XXXXLVNNVVHSFRLQQTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAYVK 118
VNN+V+SFRL T+FDKKS+++YIKGYMK IK RLQESNP+ V VFEK A +VK
Sbjct: 60 EGTETVNNLVYSFRLSPTSFDKKSYMSYIKGYMKAIKARLQESNPERVPVFEKNAIGFVK 119
Query: 119 KVIGSFKDWEFFTGESMDPDGMLVLLNYREDGTTPFVAIWKHGVKAEK 166
K++ +FKD++F+ GESMDPD M+VL+NYREDG TP++ +K G+ +EK
Sbjct: 120 KILANFKDYDFYIGESMDPDAMVVLMNYREDGITPYMIFFKDGLVSEK 167
>Hs4507669 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 172
Score = 139 bits (349), Expect = 2e-33
Identities = 72/171 (42%), Positives = 107/171 (62%), Gaps = 5/171 (2%)
Query: 1 MIIYTDIISGDELLSDAYDLK-LVDGVIYEADCDMVKVGGDNID---IGANPSAXXXXXX 56
MIIY D+IS DE+ SD Y ++ + DG+ E + MV NID IG N SA
Sbjct: 1 MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGE 60
Query: 57 XXXXXXLVN-NVVHSFRLQQTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQA 115
+ ++V + LQ+T+F K+++ YIK YMK IKG+L+E P+ V F GA
Sbjct: 61 GTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAE 120
Query: 116 YVKKVIGSFKDWEFFTGESMDPDGMLVLLNYREDGTTPFVAIWKHGVKAEK 166
+K ++ +FK+++FF GE+M+PDGM+ LL+YREDG TP++ +K G++ EK
Sbjct: 121 QIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEK 171
>7299413 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 172
Score = 130 bits (327), Expect = 8e-31
Identities = 73/171 (42%), Positives = 106/171 (61%), Gaps = 5/171 (2%)
Query: 1 MIIYTDIISGDELLSDAYDLKLVDGVIYEADCDMVKVGGDNIDI-GANPSAXXXXXXXXX 59
M IY DII+GDE+ +D Y +KLVD VIYE ++ GD+I + GAN SA
Sbjct: 1 MKIYKDIITGDEMFADTYKMKLVDDVIYEVYGKLITRQGDDIKLEGANASAEEADEGTDI 60
Query: 60 XXXLVNNVVHSFRLQQT-AF-DKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAYV 117
+VV + RL + AF DKKS+ Y+K YMK++ +L+E +PD+V +F+ +
Sbjct: 61 TSESGVDVVLNHRLTECFAFGDKKSYTLYLKDYMKKVLAKLEEKSPDQVDIFKTNMNKAM 120
Query: 118 KKVIGSFKDWEFFTGESMDPDGMLVLLNYRE--DGTTPFVAIWKHGVKAEK 166
K ++G FK+ +FFTGESMD DGM+ L+ YRE + P + +KHG++ EK
Sbjct: 121 KDILGRFKELQFFTGESMDCDGMVALVEYREINGDSVPVLMFFKHGLEEEK 171
>At3g16640 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 168
Score = 112 bits (280), Expect = 2e-25
Identities = 63/170 (37%), Positives = 99/170 (58%), Gaps = 7/170 (4%)
Query: 1 MIIYTDIISGDELLSDAYDLKLVD-GVIYEADCDMVKVGGDNIDIGANPSAXXXXXXXXX 59
M++Y D+++GDELLSD++ K ++ G+++E + V VG +++IGANPSA
Sbjct: 1 MLVYQDLLTGDELLSDSFPYKEIENGILWEVEGKWVTVGAVDVNIGANPSAEEGGEDEGV 60
Query: 60 XXXL--VNNVVHSFRLQ-QTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAY 116
V ++V +FRLQ Q +DKK F+ YIK Y+K + +L E ++ +VF+KG +
Sbjct: 61 DDSTQKVVDIVDTFRLQEQPTYDKKGFIAYIKKYIKLLTPKLSE---EDQAVFKKGIEGA 117
Query: 117 VKKVIGSFKDWEFFTGESMDPDGMLVLLNYREDGTTPFVAIWKHGVKAEK 166
K ++ D++FF GE M D LV Y+E T P + HG+K K
Sbjct: 118 TKFLLPRLSDFQFFVGEGMHDDSTLVFAYYKEGSTNPTFLYFAHGLKEVK 167
>Hs17467871 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 138
Score = 105 bits (261), Expect = 4e-23
Identities = 56/137 (40%), Positives = 82/137 (58%), Gaps = 4/137 (2%)
Query: 34 MVKVGGDNID---IGANPSAXXXXXXXXXXXXLVN-NVVHSFRLQQTAFDKKSFLTYIKG 89
MV NID IG N SA + +VV + LQ+T+F K++ YIK
Sbjct: 1 MVSRTEGNIDDSLIGGNVSAEGPEGEGTESTVITAVDVVMNHHLQETSFTKEAHKKYIKD 60
Query: 90 YMKEIKGRLQESNPDEVSVFEKGAQAYVKKVIGSFKDWEFFTGESMDPDGMLVLLNYRED 149
YMK IKG+L+E P+ V F GA +K ++ +FK++ FF GE+M+PDGM+ LL+Y ED
Sbjct: 61 YMKSIKGKLEELRPERVKPFMTGAAEQIKHILANFKNYHFFIGENMNPDGMVALLDYGED 120
Query: 150 GTTPFVAIWKHGVKAEK 166
G TP++ ++ G++ EK
Sbjct: 121 GVTPYMIFFRDGLETEK 137
>Hs11056002 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 173
Score = 103 bits (256), Expect = 1e-22
Identities = 55/172 (31%), Positives = 100/172 (57%), Gaps = 6/172 (3%)
Query: 1 MIIYTDIISGDELLSDAYDL-KLVDGVIYEADCDMVKVGGDNID---IGANPSAXXXXXX 56
MII+ D+IS +E+ SD Y + ++ +G+ E + M+ N D IG N S+
Sbjct: 1 MIIFQDLISHNEMFSDIYKIWEITNGLCLEVEQKMLSKTTGNTDDSLIGRNSSSESTEDE 60
Query: 57 XXXXXXLVN-NVVHSFRLQQTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQA 115
+ + ++V + LQ++ F K+++ YIK YMK I +L+E P+ V +F G +
Sbjct: 61 VTESTIITSVDIVTNHHLQESIFTKEAYKKYIKDYMKSINEKLEEQRPERVKLFITGNEE 120
Query: 116 YVKKVIGSFKDWEFFTGESMDPDGMLVLLNYREDGT-TPFVAIWKHGVKAEK 166
+K + +F++++FF GE+++P GM+ LLNYR+DG P ++G++ ++
Sbjct: 121 QIKHIFANFQNYQFFIGENLNPPGMVALLNYRKDGQYDPIYDFLRNGLEIKR 172
>At3g05540 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 156
Score = 89.4 bits (220), Expect = 2e-18
Identities = 56/171 (32%), Positives = 93/171 (53%), Gaps = 21/171 (12%)
Query: 1 MIIYTDIISGDELLSDAYDLKLVD-GVIYEADCDMVKVGGDNIDIGANPSAXXXXXXXXX 59
M++Y DI++GDELLSD++ K ++ G+++E + G NPS
Sbjct: 1 MLVYQDILTGDELLSDSFPYKEIENGMLWEVE-------------GKNPSGEEGGEDEGV 47
Query: 60 XXXLVN--NVVHSFRLQ-QTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAY 116
V +++ +FRLQ Q +FDKK F+ ++K Y+K++ +L N + +F+K ++
Sbjct: 48 DDQAVKVVDIIDTFRLQEQPSFDKKQFVMFMKRYIKQLSPKLDSENQE---LFKKHIESA 104
Query: 117 VKKVIGSFKDWEFFTGESMD-PDGMLVLLNYREDGTTPFVAIWKHGVKAEK 166
K ++ KD++FF GESM+ +G LV YRE T P +G+K K
Sbjct: 105 TKFLMSKLKDFQFFVGESMEGEEGSLVFAYYREGATDPTFLYLAYGLKEIK 155
>Hs8923032_2 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 77
Score = 77.4 bits (189), Expect = 8e-15
Identities = 34/76 (44%), Positives = 52/76 (67%)
Query: 91 MKEIKGRLQESNPDEVSVFEKGAQAYVKKVIGSFKDWEFFTGESMDPDGMLVLLNYREDG 150
+K IK E P+ V F GA +K ++ +FK+++FF GE+M+PDGM+ LL+YREDG
Sbjct: 1 LKVIKFLGDEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDG 60
Query: 151 TTPFVAIWKHGVKAEK 166
TP++ +K G++ EK
Sbjct: 61 VTPYMIFFKDGLEMEK 76
>CE09656 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 181
Score = 72.8 bits (177), Expect = 2e-13
Identities = 54/180 (30%), Positives = 94/180 (52%), Gaps = 14/180 (7%)
Query: 1 MIIYTDIISGDELLSDAYDLKLVDGVIYE-ADCDMVKVGGDNIDIGANPSAXXXXXXXXX 59
M+IY DI + DEL SD++ +KLVD ++YE +V+ G+ + G+NPSA
Sbjct: 1 MLIYKDIFTDDELSSDSFPMKLVDDLVYEFKGKHVVRKEGEIVLAGSNPSAEEGAEDDGS 60
Query: 60 XXXL---VNNVVHSFRLQQTAF-DKKSFLTYIKGYMKEIKGRLQESNPD--EVSVFEKGA 113
+ ++ V++ ++ + D F YIK +MK + ++++N D +V F+K
Sbjct: 61 DEHVERGIDIVLNHKLVEMNCYEDASMFKAYIKKFMKNVIDHMEKNNRDKADVDAFKKKI 120
Query: 114 QAYVKKVIGS--FKDWEFFTGESM---DPDGMLVLLNYRE-DGT-TPFVAIWKHGVKAEK 166
Q +V ++ FK+ FF GE +G + ++ YR+ DGT P + + K + EK
Sbjct: 121 QGWVVSLLAKDRFKNLAFFIGERAAEGAENGQVAIIEYRDVDGTEVPTLMLVKEAIIEEK 180
>Hs17485897 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 144
Score = 65.5 bits (158), Expect = 3e-11
Identities = 29/71 (40%), Positives = 45/71 (62%)
Query: 72 RLQQTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAYVKKVIGSFKDWEFFT 131
R+++T+F K++ YIK YMK IKGRL+E P+ V F G K + +FK+++FF
Sbjct: 34 RVKETSFTKEACKKYIKHYMKSIKGRLEEQKPERVKAFMTGPAEQTKHIFANFKNYQFFI 93
Query: 132 GESMDPDGMLV 142
GE+M+ + V
Sbjct: 94 GENMNTNASFV 104
>Hs17460089 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 168
Score = 54.7 bits (130), Expect = 6e-08
Identities = 28/92 (30%), Positives = 48/92 (51%), Gaps = 22/92 (23%)
Query: 75 QTAFDKKSFLTYIKGYMKEIKGRLQESNPDEVSVFEKGAQAYVKKVIGSFKDWEFFTGES 134
+T+ K+++ YIK Y E +K ++ +FK+++F E
Sbjct: 98 ETSSAKEAYRKYIKNYTAE----------------------QIKHILANFKNYQFIICED 135
Query: 135 MDPDGMLVLLNYREDGTTPFVAIWKHGVKAEK 166
M+PDGML LL+Y+ED TP++ +K ++ EK
Sbjct: 136 MNPDGMLALLDYQEDDVTPYMIFFKDDLEMEK 167
>Hs22052803_2 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 102
Score = 54.7 bits (130), Expect = 6e-08
Identities = 30/89 (33%), Positives = 46/89 (50%), Gaps = 3/89 (3%)
Query: 21 KLVDGVIYEADCDMVKVGGDNID---IGANPSAXXXXXXXXXXXXLVNNVVHSFRLQQTA 77
++ DG+ + +MV N D IG N SA + + V + LQ+T+
Sbjct: 3 EIADGLCLVVEGNMVSRTEGNTDDLLIGGNASAEGPEGKGTKTTVITVDTVTDYHLQETS 62
Query: 78 FDKKSFLTYIKGYMKEIKGRLQESNPDEV 106
F K ++ YIK YMK IKG+L+E P++V
Sbjct: 63 FTKNTYKNYIKDYMKTIKGKLEEQRPEKV 91
>Hs17462926 [DZ] KOG1727 Microtubule-binding protein (translationally
controlled tumor protein)
Length = 190
Score = 53.9 bits (128), Expect = 1e-07
Identities = 22/55 (40%), Positives = 36/55 (65%)
Query: 93 EIKGRLQESNPDEVSVFEKGAQAYVKKVIGSFKDWEFFTGESMDPDGMLVLLNYR 147
E +G+L+E P+ V F GA +K ++ +FK + FF GE+M+PDGM+ +Y+
Sbjct: 108 ESEGKLEEQRPERVKPFMTGAAEQIKHILANFKSYHFFIGENMNPDGMVAPQDYQ 162
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.139 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,687,922
Number of Sequences: 60738
Number of extensions: 367816
Number of successful extensions: 754
Number of sequences better than 1.0e-05: 14
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 731
Number of HSP's gapped (non-prelim): 14
length of query: 167
length of database: 30,389,216
effective HSP length: 98
effective length of query: 69
effective length of database: 24,436,892
effective search space: 1686145548
effective search space used: 1686145548
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)