ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3068 good D KOG0642 Cell cycle control, cell division, chromosome partitioning Cell-cycle nuclear protein, contains WD-40 repeats
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3068 1079939 1081600 554
(554 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR029c [D] KOG0642 Cell-cycle nuclear protein contains WD-40 re... 235 1e-61
SPBC1773.01 [D] KOG0642 Cell-cycle nuclear protein contains WD-4... 66 1e-10
CE06118 [D] KOG0642 Cell-cycle nuclear protein contains WD-40 re... 61 4e-09
Hs4507283 [D] KOG0642 Cell-cycle nuclear protein contains WD-40 ... 60 9e-09
Hs11128017 [D] KOG0642 Cell-cycle nuclear protein contains WD-40... 56 1e-07
>YMR029c [D] KOG0642 Cell-cycle nuclear protein contains WD-40 repeats
Length = 523
Score = 235 bits (600), Expect = 1e-61
Identities = 191/579 (32%), Positives = 289/579 (48%), Gaps = 102/579 (17%)
Query: 7 HYTLPGVMHYLQTEYTKNERDRINWELERCEMKSRIAQLEGENRDLKSGLVKLQNQLKDS 66
HYTLPGVMHYLQTE+TKNERDRI WELER EMK+RIA+LEGENRDLK L NQ++
Sbjct: 11 HYTLPGVMHYLQTEFTKNERDRITWELERSEMKARIAELEGENRDLKHQL----NQIQSK 66
Query: 67 GCSSSGNLNENDETGKSLPLESWEQEEELLHSKLSVQENIKEIVYLLKSPPVTDQLESLN 126
S G E K +P + LL SKL+VQEN+KEI+YLLK P +QLESLN
Sbjct: 67 AVSPEGEKEE-----KHVP-------DSLLQSKLAVQENVKEIIYLLKGPNTVNQLESLN 114
Query: 127 DKDDSVKKLESLNLFNVNNSSILKNGTDNRTEVKNEHKISNSQVDDGDLIINDKEANSTS 186
++ +L L NVN KE S
Sbjct: 115 SREAG-SELHDLEKLNVNTP---------------------------------KEEGSAK 140
Query: 187 SDVPNITLNRDWKDVINSPPGDDVSDAETVINTXXXXXXXLFSTQSNEMLKFHTYRFLQY 246
++ +I N N G S + T + + LFST +N+ T +
Sbjct: 141 TNGMDILNNALLDTKPNPKQGPSESPSPTKVKS-------LFST-ANKRENNETISKIHS 192
Query: 247 HLSSISKLKLLGNNMLSFGSDGL-LKHWLIEPSLNSNEKATKAFHCVPNLLGIFWLNKTR 305
LS + + G+ M + +D L+ ++ +LNS + +++ FW++ ++
Sbjct: 193 ELSKVDIISSYGDCMALYDADTKSLEIHQVDANLNSKLLKKISLGQDSDIMKFFWVSTSK 252
Query: 306 FMTVDET-SVKLWNVSQSDPVISWDGLKDLE------GLQSVDFKNKWLILTFVN--EIR 356
+ ++++ +KL+++S + + D L+D E + ++DFKNKWL++ N +IR
Sbjct: 253 LLVIEKSFHLKLFSISSASLISDVDLLQDSEQPFSSSDIINIDFKNKWLLIASKNKSQIR 312
Query: 357 VWEI-KIDDSSIVKVN---EFVISVPN---------KILNCLLGLTEKSLIILNGSSKQN 403
+WE+ I+ V +N + I+ N IL+C+LG+TEKSLI+L+ + Q
Sbjct: 313 IWELDNIEAPEDVPINIKETYEITHDNDDDDSNDSTNILDCILGITEKSLILLSSNPYQ- 371
Query: 404 VKISIFDFQGSLLQQIDLSHSLTQFHHTNNE---LALNRSTSKLLVRFDTE-TLIYSFDQ 459
++I+DF+G LLQ+IDL E L L+R TSKLL++ E L+YSFD+
Sbjct: 372 --LTIYDFEGKLLQKIDLKIDTILSGKPEEEGYHLFLDRKTSKLLIQLSNERLLVYSFDK 429
Query: 460 KKTILVSSTAESAISSI--FLNDLEYTVTALKDGSILVKSIKE-----DGKVIRKYNHYE 512
KK +L S+ I LND TV + +G ++++ D V+ N E
Sbjct: 430 KKVVLKEQLTPSSTLPIQLDLNDSIITV-SYSNGDFEFRNLENLKPSIDEFVVADINFSE 488
Query: 513 HPEKVPAEVQPIAIASTVIDDTPVIVSGGYNGVIRLEKI 551
E V + ++ ++D TPV+++ N + L KI
Sbjct: 489 RKEPV------VFSSNLIVDSTPVLITVNKNNEVLLHKI 521
>SPBC1773.01 [D] KOG0642 Cell-cycle nuclear protein contains WD-40 repeats
Length = 612
Score = 66.2 bits (160), Expect = 1e-10
Identities = 58/194 (29%), Positives = 94/194 (47%), Gaps = 28/194 (14%)
Query: 8 YTLPGVMHYLQTEYTKNERDRINWELERCEMKSRIAQLEGENRDLKSGL-------VKLQ 60
YTL GV+ YLQ E KNERD WE+ER E+K R+AQLE E L+ L L+
Sbjct: 22 YTLQGVIQYLQYEAFKNERDHNLWEIERAELKIRVAQLERERAKLEQSLSFQQRRAEMLE 81
Query: 61 NQLKDSGCSSSGNLNENDE----TGKSLPLESWEQEEELLHSKLSVQENIKEIVYLLKSP 116
L++ + ++ + DE + + E LL SK ++++++EIVYL
Sbjct: 82 KSLRELRKDKNISVKDLDEFHLLDKPAANNTKADAEACLLKSKNYIKKSLQEIVYLTNMQ 141
Query: 117 P-------------VTDQLESLNDKDDSVKKLE-SLNLFNVNNSSILKNGTDNRTEVKNE 162
P + ES N + ++ +E S N NVN+++ + +N
Sbjct: 142 PNVSWNVLQEPTRGIKVPKESNNTQQNNQFVMEPSQNKGNVNDANFFE---VEYARNENM 198
Query: 163 HKISNSQVDDGDLI 176
+K+S+S++ DL+
Sbjct: 199 NKLSSSELISDDLL 212
>CE06118 [D] KOG0642 Cell-cycle nuclear protein contains WD-40 repeats
Length = 638
Score = 61.2 bits (147), Expect = 4e-09
Identities = 28/54 (51%), Positives = 40/54 (73%), Gaps = 3/54 (5%)
Query: 8 YTLPGVMHYLQTEYTKNERDRINWELERCEMKSRIAQLEGENR---DLKSGLVK 58
YT+ G++H++Q E+TKNE DR WE ER EM++RIA L+GE + +LK LV+
Sbjct: 24 YTMSGILHFIQHEWTKNELDRTRWEAERAEMQARIAFLQGERKGQENLKQDLVR 77
>Hs4507283 [D] KOG0642 Cell-cycle nuclear protein contains WD-40 repeats
Length = 780
Score = 60.1 bits (144), Expect = 9e-09
Identities = 55/206 (26%), Positives = 98/206 (46%), Gaps = 30/206 (14%)
Query: 6 AHYTLPGVMHYLQTEYTKNERDRINWELERCEMKSRIAQLEGENR---DLKSGLVK---- 58
A Y+LPG++H+LQ E+ + E +R WE+ER E++++IA L+GE + +LK LV+
Sbjct: 45 AQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRIKM 104
Query: 59 -----LQNQLKDSGCSSSGNLNENDETGKSLPLESWEQEE--ELLHSKLSVQENIKEIVY 111
Q + K LN+ D S + + E +S+L ++ + +
Sbjct: 105 LEYALKQERAKYHKLKYGTELNQGDMKPPSYDSDEGNETEVQPQQNSQLMWKQGRQLLRQ 164
Query: 112 LLKSPPVTDQLESLNDKDDSVKKLESLNLFNVN--------NSSILKNGTDNRTEVKNEH 163
L+ TD + D K++ +L F+++ N + NGT+ EVK
Sbjct: 165 YLQEVGYTDTI-----LDVKSKRVRALLGFSIDVTDREDDKNQDSVVNGTE--AEVKETA 217
Query: 164 KISNSQV-DDGDLIINDKEANSTSSD 188
I+ S++ D ++ N K S ++D
Sbjct: 218 MIAKSELTDSASVLDNFKFLESAAAD 243
>Hs11128017 [D] KOG0642 Cell-cycle nuclear protein contains WD-40 repeats
Length = 713
Score = 56.2 bits (134), Expect = 1e-07
Identities = 45/158 (28%), Positives = 78/158 (48%), Gaps = 17/158 (10%)
Query: 9 TLPGVMHYLQTEYTKNERDRINWELERCEMKSRIAQLEGENR---DLKSGLVK------- 58
T+PG++HY+Q E+ + E +R +WE+ER E+++RIA L+GE + +LK LV+
Sbjct: 64 TIPGILHYIQHEWARFEMERAHWEVERAELQARIAFLQGERKGQENLKKDLVRRIKMLEY 123
Query: 59 --LQNQLKDSGCSSSGNLNEND---ETGKSLPLESWEQEEELLHSKLSVQENIKEIVYLL 113
Q + K LN+ D T +S + E +S+L+ ++ + + L
Sbjct: 124 ALKQERAKYHKLKYGTELNQGDLKMPTFESEETKDTEAPTAPQNSQLTWKQGRQLLRQYL 183
Query: 114 KSPPVTDQLESLNDKDDSVKKLESLNLFNVNNSSILKN 151
+ TD + L+ + V+ L L+ N S KN
Sbjct: 184 QEVGYTDTI--LDVRSQRVRSLLGLSNSEPNGSVETKN 219
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,114,856
Number of Sequences: 60738
Number of extensions: 1428819
Number of successful extensions: 4373
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4360
Number of HSP's gapped (non-prelim): 6
length of query: 554
length of database: 30,389,216
effective HSP length: 111
effective length of query: 443
effective length of database: 23,647,298
effective search space: 10475753014
effective search space used: 10475753014
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)