ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3411 good O KOG1863 Posttranslational modification, protein turnover, chaperones Ubiquitin carboxyl-terminal hydrolase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3411 1201452 1202576 375
(375 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 516 e-146
SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 352 7e-97
SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 317 2e-86
At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 273 2e-73
At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 273 3e-73
Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 269 4e-72
7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 260 3e-69
CE16183 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 233 5e-61
CE16182 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 233 5e-61
7295436 [O] KOG4598 Putative ubiquitin-specific protease 141 1e-33
ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 107 3e-23
CE13299 [O] KOG4598 Putative ubiquitin-specific protease 97 3e-20
At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 89 8e-18
Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 87 4e-17
Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 71 3e-12
At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 65 2e-10
At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 64 3e-10
At3g58250 [DR] KOG1987 Speckle-type POZ protein SPOP and related... 62 1e-09
Hs12383078 [O] KOG1864 Ubiquitin-specific protease 60 4e-09
At3g58270 [DR] KOG1987 Speckle-type POZ protein SPOP and related... 60 7e-09
Hs20483065 [O] KOG1864 Ubiquitin-specific protease 59 9e-09
Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 56 8e-08
Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 56 8e-08
HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase 55 2e-07
Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 55 2e-07
CE09996 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase 55 2e-07
CE09811 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 55 2e-07
Hs20548613 [O] KOG1864 Ubiquitin-specific protease 54 3e-07
At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 54 3e-07
Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 54 4e-07
Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase 54 5e-07
7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase 53 6e-07
YMR223w [O] KOG1867 Ubiquitin-specific protease 51 2e-06
Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 51 3e-06
Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase 51 3e-06
SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease 50 5e-06
Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase 50 5e-06
CE26241 [O] KOG1867 Ubiquitin-specific protease 49 9e-06
>YMR304w [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 516 bits (1330), Expect = e-146
Identities = 243/377 (64%), Positives = 299/377 (78%), Gaps = 5/377 (1%)
Query: 3 EVQVLGRIQEAVDLGKSFNDFLPAI-KDLETRAEGSFTWRIDNWYELTNDKYHSGKYKFD 61
E+ +G + + KS LP +++ET E SFTW I +W ELTN KY+S +++
Sbjct: 6 ELGSIGTVFPGSPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIG 65
Query: 62 GLEWDLLIFPQGNHSRGVSIYLAPHPDPELVSVDND----NTDWHVCAQFAIVFSKPGED 117
EWD+L+FPQGNH++GV++YL PHP+ +L + + DW+ CAQFAI S+PG
Sbjct: 66 DFEWDILLFPQGNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNG 125
Query: 118 ANVQLSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNKPSGFLNQGAVNISVFIRSIEDP 177
+ L NK+ HRF A D DWGF+N I+++ LKH S+ +P FLN+G +NI+ ++R ++DP
Sbjct: 126 DTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDP 185
Query: 178 TGVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTN 237
TGVLWHNFLNYDSKK+TG+VGF+NQGATCYLNSLLQSY FTK FRKLVY+IPTE E+P N
Sbjct: 186 TGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNN 245
Query: 238 SVALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGT 297
SV LALQRAFY LQ S PLDT ELT+SFGWDT ++FTQHDVQELNRILMDRLE+ MKGT
Sbjct: 246 SVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGT 305
Query: 298 SVEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMN 357
VEGK+NE+FVGKMKS IKCINVDYES+RVEDFWD+QLNVK+ KNLQESF+ YIE+ELMN
Sbjct: 306 PVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMN 365
Query: 358 GENQYAAQDHGLQDAQK 374
GENQYAAQD+GLQDAQK
Sbjct: 366 GENQYAAQDYGLQDAQK 382
>SPBC713.02c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 352 bits (902), Expect = 7e-97
Identities = 182/378 (48%), Positives = 248/378 (65%), Gaps = 29/378 (7%)
Query: 20 FNDFLPAIKDLETRAEGSFTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQG-NHSRG 78
+N + DLE A S++W + N+ L DK +S +K W +++FP+G N +
Sbjct: 36 YNSLVHHEPDLEEAAHASYSWVVKNFSTL-EDKTYSPLFKAGHTTWRIVLFPKGCNQTEY 94
Query: 79 VSIYL----------------------APHPDPELVSVDNDNTDWHVCAQFAIVFSKPGE 116
S++L P DPE+V ND T + CAQFA+ S +
Sbjct: 95 ASVFLEYLPQCKVEAIRKYEAELAAGKTPTIDPEIV---NDET-YSCCAQFALSLSNV-Q 149
Query: 117 DANVQLSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNKPSGFLNQGAVNISVFIRSIED 176
D V N + HRF + KDWGF+ F+++ + + P FL + ISV +R ++D
Sbjct: 150 DPTVMQINTSHHRFRSEVKDWGFTRFVDLRKIAVPTPEFPVPFLENDEICISVTVRVLQD 209
Query: 177 PTGVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPT 236
PTGVLWH+F+NY+SKK TG+VG KNQGATCY+NSLLQS FT +FRK VY+IPT++++
Sbjct: 210 PTGVLWHSFVNYNSKKETGYVGLKNQGATCYMNSLLQSLFFTNIFRKTVYKIPTDNDDSR 269
Query: 237 NSVALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKG 296
+SVA ALQR FY L+ +EP+ TTELT+SFGW++ D+F QHD+QE NR+L D LE +MKG
Sbjct: 270 DSVAYALQRVFYNLEKQREPVSTTELTRSFGWNSFDSFMQHDIQEFNRVLQDNLEKKMKG 329
Query: 297 TSVEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELM 356
T VE +N++FVGKMKS +KCI+V+YESSRVEDFWDIQLNVK M L++SF I+VE +
Sbjct: 330 TEVENALNDIFVGKMKSYVKCIDVNYESSRVEDFWDIQLNVKGMDTLEDSFRDAIQVETL 389
Query: 357 NGENQYAAQDHGLQDAQK 374
G+N+Y A+ HGLQDA K
Sbjct: 390 TGDNKYYAEGHGLQDAHK 407
>SPCC188.08c [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1108
Score = 317 bits (812), Expect = 2e-86
Identities = 166/351 (47%), Positives = 224/351 (63%), Gaps = 8/351 (2%)
Query: 26 AIKDLETRAEGSFTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQGN-HSRG-VSIYL 83
A+ D E FTW I +W+EL + S ++ ++ + FPQG S G SI+L
Sbjct: 46 ALPDYEESGFQRFTWHIKSWHELDR-RAVSPQFAVGSRQFKITYFPQGTLQSAGFTSIFL 104
Query: 84 APHPDPELVSVDNDNTDWHVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFI 143
P E + + + C QFA V S P + + + ++N A RF+ DWGF+ F
Sbjct: 105 EYIPSEE----EKLSNKYGCCCQFAFVISNPRKPS-LSVANSAHCRFSPEIVDWGFTQFA 159
Query: 144 EVDYLKHYSRNKPSGFLNQGAVNISVFIRSIEDPTGVLWHNFLNYDSKKMTGFVGFKNQG 203
E+ L + GA+ ++ ++R ++DPTGVLWH+F +YDSK TG+VG KNQG
Sbjct: 160 ELKKLLCRQAPDVPPIVEDGALLLTAYVRILKDPTGVLWHSFNDYDSKIATGYVGLKNQG 219
Query: 204 ATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKEPLDTTELT 263
ATCY+NSLLQS + FR++VYQIPT+ +S+A ALQR FY LQ EP+ TTELT
Sbjct: 220 ATCYMNSLLQSLYIIHAFRRIVYQIPTDSPQGKDSIAYALQRCFYNLQFMNEPVSTTELT 279
Query: 264 KSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVGKMKSCIKCINVDYE 323
KSFGWD+ D+F QHDVQE NR+L D LE M+ T VE + LFVGKMKS I C+NV++E
Sbjct: 280 KSFGWDSLDSFMQHDVQEFNRVLQDNLERSMRDTKVENALTNLFVGKMKSYIACVNVNFE 339
Query: 324 SSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQYAAQDHGLQDAQK 374
S+R ED+WDIQLNVK MKNL++SF YI+VE + G+N Y A +G Q+A+K
Sbjct: 340 SARSEDYWDIQLNVKGMKNLEDSFRSYIQVETLEGDNCYFADTYGFQEAKK 390
>At3g11910 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1124
Score = 273 bits (699), Expect = 2e-73
Identities = 151/338 (44%), Positives = 214/338 (62%), Gaps = 18/338 (5%)
Query: 38 FTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQGNHSRGVSIYLAPHPDPELVSVDND 97
FTW I + L K++S + G +W +LIFP+GN+ +S+YL ++ N
Sbjct: 65 FTWTIPMFTRLNTRKHYSDVFVVGGYKWRILIFPKGNNVDHLSMYL------DVADAANL 118
Query: 98 NTDWHVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNKPS 157
W +QF++ + + + H+F A + DWGF++F+ + L +R
Sbjct: 119 PYGWSRYSQFSLAVVNQVNN-RYSIRKETQHQFNARESDWGFTSFMPLSELYEPTR---- 173
Query: 158 GFLNQGAVNISVFIRSIEDPTGVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQSYHF 217
G+L VN +V I + VL ++ +YDSKK TGFVG KNQGATCY+NSLLQ+ +
Sbjct: 174 GYL----VNDTVLIEAEVAVRKVL--DYWSYDSKKETGFVGLKNQGATCYMNSLLQTLYH 227
Query: 218 TKLFRKLVYQIPT-EDENPTNSVALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFTQ 276
FRK VY +PT E++ PT S+ LALQ FY LQ + + T ELTKSFGWDT D+F Q
Sbjct: 228 IPYFRKAVYHMPTTENDAPTASIPLALQSLFYKLQYNDTSVATKELTKSFGWDTYDSFMQ 287
Query: 277 HDVQELNRILMDRLEHRMKGTSVEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLN 336
HDVQELNR+L ++LE +MKGT VEG I +LF G + I+CINVDY+S+R E F+D+QL+
Sbjct: 288 HDVQELNRVLCEKLEDKMKGTVVEGTIQKLFEGHHMNYIECINVDYKSTRKESFYDLQLD 347
Query: 337 VKDMKNLQESFEQYIEVELMNGENQYAAQDHGLQDAQK 374
VK K++ SF++Y+EVE + G+N+Y A+ H LQDA+K
Sbjct: 348 VKGCKDVYASFDKYVEVERLEGDNKYHAEGHDLQDAKK 385
>At5g06600 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1115
Score = 273 bits (698), Expect = 3e-73
Identities = 151/338 (44%), Positives = 214/338 (62%), Gaps = 18/338 (5%)
Query: 38 FTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQGNHSRGVSIYLAPHPDPELVSVDND 97
FTW I N+ K++S + G +W +LIFP+GN+ +S+YL ++ +
Sbjct: 56 FTWTIPNFSRQNTRKHYSDVFVVGGYKWRILIFPKGNNVDHLSMYL------DVSDAASL 109
Query: 98 NTDWHVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNKPS 157
W AQF++ + + H+F A + DWGF++F+ + L SR
Sbjct: 110 PYGWSRYAQFSLAVVNQIH-TRYTVRKETQHQFNARESDWGFTSFMPLSELYDPSR---- 164
Query: 158 GFLNQGAVNISVFIRSIEDPTGVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQSYHF 217
G+L VN +V + + VL ++ +YDSKK TGFVG KNQGATCY+NSLLQ+ +
Sbjct: 165 GYL----VNDTVLVEAEVAVRKVL--DYWSYDSKKETGFVGLKNQGATCYMNSLLQTLYH 218
Query: 218 TKLFRKLVYQIPT-EDENPTNSVALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFTQ 276
FRK VY +PT E++ PT S+ LALQ FY LQ + + T ELTKSFGWDT D+F Q
Sbjct: 219 IPYFRKAVYHMPTTENDAPTASIPLALQSLFYKLQYNDTSVATKELTKSFGWDTYDSFMQ 278
Query: 277 HDVQELNRILMDRLEHRMKGTSVEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLN 336
HDVQELNR+L ++LE +MKGT VEG I +LF G + I+CINVD++S+R E F+D+QL+
Sbjct: 279 HDVQELNRVLCEKLEDKMKGTVVEGTIQQLFEGHHMNYIECINVDFKSTRKESFYDLQLD 338
Query: 337 VKDMKNLQESFEQYIEVELMNGENQYAAQDHGLQDAQK 374
VK K++ SF++Y+EVE + G+N+Y A+ HGLQDA+K
Sbjct: 339 VKGCKDVYASFDKYVEVERLEGDNKYHAEGHGLQDAKK 376
>Hs4507857 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1102
Score = 269 bits (688), Expect = 4e-72
Identities = 149/350 (42%), Positives = 212/350 (60%), Gaps = 24/350 (6%)
Query: 29 DLETRAEGSFTWRIDNWYELTNDKYHSGKYKFDGLEWDLLI----FPQGNHSRGVSIYLA 84
D R+E +F + ++ + L+ + S L W +++ +P H + V +L
Sbjct: 62 DTSWRSEATFQFTVERFSRLS-ESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ 120
Query: 85 PHPDPELVSVDNDNTDWHVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFIE 144
+ ++D+T W AQ + +D S + SH F + DWGFSNF+
Sbjct: 121 -------CNAESDSTSWSCHAQAVLKIINYRDDEK-SFSRRISHLFFHKENDWGFSNFMA 172
Query: 145 VDYLKHYSRNKPSGFLNQGAVNISVFIRSIEDPTGVLWHNFLNYDSKKMTGFVGFKNQGA 204
+ + GF++ V VF+++ + P GV W DSKK TG+VG KNQGA
Sbjct: 173 WSEVT----DPEKGFIDDDKVTFEVFVQA-DAPHGVAW------DSKKHTGYVGLKNQGA 221
Query: 205 TCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKEPLDTTELTK 264
TCY+NSLLQ+ FT RK VY +PTE ++ + SV LALQR FY LQ S +P+ T +LTK
Sbjct: 222 TCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTK 281
Query: 265 SFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVGKMKSCIKCINVDYES 324
SFGW+T D+F QHDVQEL R+L+D +E++MKGT VEG I +LF GKM S I+C VDY S
Sbjct: 282 SFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRS 341
Query: 325 SRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQYAAQDHGLQDAQK 374
R ED++DIQL++K KN+ ESF Y+ VE ++G+N+Y A +HGLQ+A+K
Sbjct: 342 DRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEK 391
>7292738 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1129
Score = 260 bits (664), Expect = 3e-69
Identities = 146/349 (41%), Positives = 214/349 (60%), Gaps = 26/349 (7%)
Query: 28 KDLETRAEGSFTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQGNHSRGVSIYLAPHP 87
K+ + R+E +F++ ++N +L + + Y L W +++ P + R + +L
Sbjct: 94 KEDQFRSETTFSFTVENVVQLKSQRLSPPVY-VRMLPWRIMVIP---NDRALGFFLQ--- 146
Query: 88 DPELVSVDNDNTDW--HVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFIEV 145
+ +ND+ W + A+ + KP DA + H F + + D+G+SNFI
Sbjct: 147 ----CNGENDSPTWSCNAIAELRLKCHKP--DAQPFTRARIKHLFYSKENDYGYSNFITW 200
Query: 146 DYLKHYSRNKPSGFLNQGAVNISVFIRSIEDPTGVLWHNFLNYDSKKMTGFVGFKNQGAT 205
LK ++ +++ ++ + V + + + P GVLW DSKK TG+VG KNQGAT
Sbjct: 201 QELKDSEKS----YVHNNSITLEVHVVA-DAPHGVLW------DSKKHTGYVGLKNQGAT 249
Query: 206 CYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKEPLDTTELTKS 265
CY+NSLLQ+ +FT R VY+IPTE ++ + SV L+LQR F+ LQ P+ T +LTKS
Sbjct: 250 CYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHELQFGDRPVGTKKLTKS 309
Query: 266 FGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVGKMKSCIKCINVDYESS 325
FGW+T D+F QHDVQE R+L+D+LE +MKGT +EG I LF GKM S IKC NVDY S+
Sbjct: 310 FGWETLDSFMQHDVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNST 369
Query: 326 RVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQYAAQDHGLQDAQK 374
R E F+DIQLN+KD KN+ ESF+ Y+ E + G+N+Y A HGLQ+A K
Sbjct: 370 RYETFYDIQLNIKDKKNIYESFQDYVAPETLEGDNKYDAGVHGLQEASK 418
>CE16183 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1130
Score = 233 bits (593), Expect = 5e-61
Identities = 123/256 (48%), Positives = 170/256 (66%), Gaps = 15/256 (5%)
Query: 122 LSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNKPSGFLNQGAVNISVFIR---SIEDPT 178
+ K H F T+ DWGFSN+ + D L N G++ VN ++ +R + + PT
Sbjct: 127 IQKKIHHSFHNTEVDWGFSNYDQYDTLC----NPKDGYV----VNDTIKLRCRFTADVPT 178
Query: 179 GVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNS 238
G N++ +DSK+ TG +G +NQGATCY+NS+LQS++FT FR+ VY + E ++
Sbjct: 179 GA---NYM-WDSKRHTGCIGLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPNESN 234
Query: 239 VALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTS 298
+ LA+QR FY LQ + E ++T LT++FGWD DAF QHDVQE R+L+D LE +MKGTS
Sbjct: 235 IVLAMQRVFYELQMASEAVETNSLTRAFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTS 294
Query: 299 VEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNG 358
E I LF G MKS IKC++VDYESSR E F+D+QLNV M +L+ +FE Y E+++
Sbjct: 295 EEKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILDD 354
Query: 359 ENQYAAQDHGLQDAQK 374
EN+Y A DHGLQ A+K
Sbjct: 355 ENKYDAGDHGLQRAEK 370
>CE16182 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1133
Score = 233 bits (593), Expect = 5e-61
Identities = 123/256 (48%), Positives = 170/256 (66%), Gaps = 15/256 (5%)
Query: 122 LSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNKPSGFLNQGAVNISVFIR---SIEDPT 178
+ K H F T+ DWGFSN+ + D L N G++ VN ++ +R + + PT
Sbjct: 127 IQKKIHHSFHNTEVDWGFSNYDQYDTLC----NPKDGYV----VNDTIKLRCRFTADVPT 178
Query: 179 GVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNS 238
G N++ +DSK+ TG +G +NQGATCY+NS+LQS++FT FR+ VY + E ++
Sbjct: 179 GA---NYM-WDSKRHTGCIGLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPNESN 234
Query: 239 VALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTS 298
+ LA+QR FY LQ + E ++T LT++FGWD DAF QHDVQE R+L+D LE +MKGTS
Sbjct: 235 IVLAMQRVFYELQMASEAVETNSLTRAFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTS 294
Query: 299 VEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNG 358
E I LF G MKS IKC++VDYESSR E F+D+QLNV M +L+ +FE Y E+++
Sbjct: 295 EEKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILDD 354
Query: 359 ENQYAAQDHGLQDAQK 374
EN+Y A DHGLQ A+K
Sbjct: 355 ENKYDAGDHGLQRAEK 370
>7295436 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1248
Score = 141 bits (356), Expect = 1e-33
Identities = 70/178 (39%), Positives = 109/178 (60%), Gaps = 7/178 (3%)
Query: 195 GFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTS- 253
G+VG NQ TCYLNSLLQ+ T FR +Y+ +++N ++ LQ+ F LQTS
Sbjct: 86 GYVGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFDNDNEAKNIPYQLQKLFLNLQTSP 145
Query: 254 KEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVGKMKS 313
K ++TT+LT+SFGWD+ +A+ QHD+QEL R++ D LEH+ K T I+ L+ GKM
Sbjct: 146 KAAVETTDLTRSFGWDSTEAWQQHDIQELCRVMFDALEHKFKNTKQANLISNLYEGKMND 205
Query: 314 CIKCINVDYESSRVEDFWDIQLNVKDM------KNLQESFEQYIEVELMNGENQYAAQ 365
+KC+ + E +R + F DI L V+ +++E+ +++ E ++G NQY +
Sbjct: 206 YVKCLECNTEKTREDTFLDIPLPVRPFGSSSAYGSIEEALRAFVQPETLDGNNQYLCE 263
>ECU03g0580 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 933
Score = 107 bits (267), Expect = 3e-23
Identities = 67/194 (34%), Positives = 108/194 (55%), Gaps = 19/194 (9%)
Query: 188 YDSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAF 247
Y+SK+ TG+VG +N GATCY+NSL+Q+ FR V+ + P V L LQ+ F
Sbjct: 102 YNSKEETGYVGLRNLGATCYINSLMQALFSIAKFRNDVFGL-----EPRGRV-LLLQKLF 155
Query: 248 YLLQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSV-----EGK 302
+QT + P+DTT+ + W D D+ E +++ D LE K V +G+
Sbjct: 156 KEMQTGEHPVDTTDFVVNNIW-VDDVHVHQDIHEFSKVFFDSLEKDSKRKDVIEDMIQGE 214
Query: 303 INELFVGKMKSCIKCINVDYESSRVE--DFWDIQLNVKDMKNLQESFEQYIEVELMNGEN 360
+ GK C++ I ++ +VE DF++ +L+ NLQES ++Y++ E+++G N
Sbjct: 215 LVTYINGKC-GCVRRIKEKFQDIQVEIRDFFNNKLS----SNLQESLKRYVKSEILDGNN 269
Query: 361 QYAAQDHGLQDAQK 374
+Y + HGL DA+K
Sbjct: 270 RYNCEKHGLVDAKK 283
>CE13299 [O] KOG4598 Putative ubiquitin-specific protease
Length = 1292
Score = 97.4 bits (241), Expect = 3e-20
Identities = 49/130 (37%), Positives = 79/130 (60%), Gaps = 7/130 (5%)
Query: 252 TSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVGKM 311
+ + L+T +LT+SFGW + +A+ QHDVQEL R++ D LEH+ KGT E I +L+ G M
Sbjct: 119 SENDSLETKDLTQSFGWTSNEAYDQHDVQELCRLMFDALEHKWKGTEHEKLIQDLYRGTM 178
Query: 312 KSCIKCINVDYESSRVEDFWDIQLNVKDM------KNLQESFEQYIEVELMNGENQYAAQ 365
+ + C+ ES + + F D+ L VK K+++E+ +++ EL++G NQY +
Sbjct: 179 EDFVACLKCGRESVKTDYFLDLPLAVKPFGAIHAYKSVEEALTAFVQPELLDGSNQYMCE 238
Query: 366 D-HGLQDAQK 374
+ QDA K
Sbjct: 239 NCKSKQDAHK 248
>At3g49600_2 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1035
Score = 89.4 bits (220), Expect = 8e-18
Identities = 58/173 (33%), Positives = 90/173 (51%), Gaps = 14/173 (8%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTE--DENPTNSVALALQRAFYLLQTSKE 255
G N GATCY NS+LQ + FR+ V+ + +NP V + R F L S++
Sbjct: 75 GLTNLGATCYANSILQCLYMNTAFREGVFSVEVHVLKQNP---VLDQIARLFAQLHASQK 131
Query: 256 P-LDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGK--INELFVGKMK 312
+D+ K+ D G Q D E +L+ LE + + V+ K + +LF G +
Sbjct: 132 SFVDSDAFVKTLELDNG---VQQDTHEFLTLLLSLLERCLLHSGVKAKTIVQDLFSGSVS 188
Query: 313 ---SCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
+C KC SS++EDF+ ++LNVK +K+L S Y+ +E +NG+NQY
Sbjct: 189 HVTTCSKCGRDSEASSKMEDFYALELNVKGLKSLDASLNDYLSLEQLNGDNQY 241
>Hs18860907_1 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 622
Score = 87.0 bits (214), Expect = 4e-17
Identities = 54/197 (27%), Positives = 93/197 (46%), Gaps = 20/197 (10%)
Query: 187 NYDSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPT-------------EDE 233
N + +K FVG N GATCY+N+ LQ + R+ +Y P+ E +
Sbjct: 79 NCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKD 138
Query: 234 NPTNSVALALQRAFYLLQTS-KEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLE- 291
++ LQ F LLQ S + +D + K+ G DTG Q D QE +++ M LE
Sbjct: 139 YEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTGQ---QQDAQEFSKLFMSLLED 195
Query: 292 --HRMKGTSVEGKINELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQ 349
+ K V + + F G+ C ES + F++++LN++ K L + +
Sbjct: 196 TLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGHKQLTDCISE 255
Query: 350 YIEVELMNGENQYAAQD 366
+++ E + G+N+Y ++
Sbjct: 256 FLKEEKLEGDNRYFCEN 272
>Hs22043041 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 959
Score = 70.9 bits (172), Expect = 3e-12
Identities = 44/177 (24%), Positives = 82/177 (45%), Gaps = 3/177 (1%)
Query: 189 DSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAF- 247
DS+ +GFVG +N GATCY+N++ Q + + + + + +NP +SV +Q F
Sbjct: 20 DSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFG 79
Query: 248 YLLQTSKEPLDTTELTKSFGWDTGDAFT--QHDVQELNRILMDRLEHRMKGTSVEGKINE 305
+L+++ + K F + + Q D E L+D+++ +K +
Sbjct: 80 HLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKN 139
Query: 306 LFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
F G C + + R E F + L V ++L+ S +Q++ E++ G N Y
Sbjct: 140 TFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAY 196
>At3g14400 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 661
Score = 65.1 bits (157), Expect = 2e-10
Identities = 46/185 (24%), Positives = 85/185 (45%), Gaps = 17/185 (9%)
Query: 197 VGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIP-----TEDENPTNSVALALQRAFYLLQ 251
+G +N G TCYLNS+LQ FT T+ + P V + R+ +
Sbjct: 15 LGLRNLGNTCYLNSVLQCLTFTPPLANFCLTHKHSSHCTKRDCPFCIVEKRIARSLSVDL 74
Query: 252 TSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEH---RMKGTSVEGK------ 302
T+ P + K F + Q D E R ++D + R+K G
Sbjct: 75 TTDAPNKISSCLKIFA-EHFKLGRQEDAHEFLRYVIDACHNTSLRLKKLRYNGNEPFNGN 133
Query: 303 --INELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGEN 360
+ E+F G ++S +KC++ ES++ ++ DI L + +++ES +++ + E+++G N
Sbjct: 134 SVVKEIFGGALQSQVKCLSCGAESNKADEIMDISLEILQSSSVKESLQKFFQSEILDGNN 193
Query: 361 QYAAQ 365
+Y +
Sbjct: 194 KYRCE 198
>At1g17110 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 891
Score = 64.3 bits (155), Expect = 3e-10
Identities = 52/185 (28%), Positives = 93/185 (50%), Gaps = 24/185 (12%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNS-----VALALQRAFYLLQT 252
G N G +CY N++LQS TK LV + + + S + L++ +L+
Sbjct: 406 GLVNCGNSCYANAVLQSLTCTK---PLVAYLLRRSHSRSCSGKDWCLMCELEQHVMMLRE 462
Query: 253 SKEPLDTTELT---KSFGWDTGDAFTQHDVQELNRILMDRLE----HRMKG-TSVEGKIN 304
S PL + + +S GD +Q D E R+L+ ++ R+ G T V+ ++
Sbjct: 463 SGGPLSASRILSHMRSINCQIGDG-SQEDAHEFLRLLVASMQSICLERLGGETKVDPRLQ 521
Query: 305 E------LFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKD-MKNLQESFEQYIEVELMN 357
E +F G+++S +KC+ D+ES R E+ D+ L + +++LQ++ Q+ E ++
Sbjct: 522 ETTLVQHMFGGRLRSKVKCLRCDHESERYENIMDLTLEIYGWVESLQDALTQFTRPEDLD 581
Query: 358 GENQY 362
GEN Y
Sbjct: 582 GENMY 586
>At3g58250 [DR] KOG1987 Speckle-type POZ protein SPOP and related proteins
with TRAF MATH and BTB/POZ domains
Length = 317
Score = 62.0 bits (149), Expect = 1e-09
Identities = 52/178 (29%), Positives = 84/178 (46%), Gaps = 18/178 (10%)
Query: 38 FTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQGNHSRG--VSIYLAPHPDPELVSVD 95
F+W I N+ L ++K +S ++ DG W LL FP+GN ++ +S+YL ++ +
Sbjct: 11 FSWVIKNFSSLQSEKIYSDQFVIDGCRWRLLAFPKGNDTKSDHLSLYL------DVAESE 64
Query: 96 NDNTDWHVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFIEVDYLKHYSRNK 155
+ W AQF+ + Q + H F DWGF+N + + LK +
Sbjct: 65 SLPCGWRRHAQFSFTIVNHIPEKCSQ-RKETIHWFCEKVSDWGFTNLVPLIELK----AE 119
Query: 156 PSGFLNQGAVNISVFIRSIEDPTGVLWHNFLNYDSKKMTGFVGFKNQGATCYLNSLLQ 213
SGFL +G + I V I +E G+L N +S + GF +Q Y+ SL +
Sbjct: 120 DSGFLVKGELKIVVEIEVLE-VIGLL--NVSESESMDVNGFHVLPSQAK--YVKSLFE 172
>Hs12383078 [O] KOG1864 Ubiquitin-specific protease
Length = 366
Score = 60.5 bits (145), Expect = 4e-09
Identities = 50/208 (24%), Positives = 86/208 (41%), Gaps = 30/208 (14%)
Query: 196 FVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKE 255
+ G N G TCY NS+LQ+ +F + FR+ V + + N + L F+ + T K+
Sbjct: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLT-CLADLFHSIATQKK 92
Query: 256 PLDTTELTKSFGW-----DTGDAFTQHDVQELNRILM----DRLEHRMKGTSVEGK---- 302
+ K D D + Q D E L+ D L+ K GK
Sbjct: 93 KVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNG 152
Query: 303 ---------------INELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESF 347
++E+F G + + +C+N + SS+ EDF D+ ++V+ ++
Sbjct: 153 NMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCL 212
Query: 348 EQYIEVELMNGENQYAAQD-HGLQDAQK 374
+ E + E +Y + Q+AQK
Sbjct: 213 RDFSNTETLCSEQKYYCETCCSKQEAQK 240
>At3g58270 [DR] KOG1987 Speckle-type POZ protein SPOP and related proteins
with TRAF MATH and BTB/POZ domains
Length = 343
Score = 59.7 bits (143), Expect = 7e-09
Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 35 EGSFTWRIDNWYELTNDKYHSGKYKFDGLEWDLLIFPQGNHSRGVSIYLAPHPDPELVSV 94
+ FTW I N+ + K +S ++ DG +W LL FP+GN +S+YLA L
Sbjct: 6 DNKFTWVIKNFSSQQSRKNYSDEFFVDGCKWRLLAFPKGNGVEKLSLYLAVAGSEFL--- 62
Query: 95 DNDNTDWHVCAQFAIVFSKPGEDANVQLSNKASHRFTATDKDWGFSNFIEVDYLKHYSRN 154
D H F++V E + + + + F A+ DWGF++ + + L +
Sbjct: 63 -PDGWRRHAYFHFSVVNQLSDE---LSQARETKNWFDASTSDWGFTSMLSLKKL----HD 114
Query: 155 KPSGFLNQGAVNISVFIRSIE 175
K GFL G + I V + +E
Sbjct: 115 KDGGFLVNGELKIVVDVSVLE 135
>Hs20483065 [O] KOG1864 Ubiquitin-specific protease
Length = 749
Score = 59.3 bits (142), Expect = 9e-09
Identities = 53/171 (30%), Positives = 76/171 (43%), Gaps = 31/171 (18%)
Query: 190 SKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYL 249
+K TG +G N G TCY+NS+LQ+ FR V ++ EN + + LQ F
Sbjct: 165 AKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRL---TENNSQPLMTKLQWLFGF 221
Query: 250 LQTSKEPLDTTELTKSFGWDTG-DAFTQHDVQELNRILMDRL-EHRMKGTSVEGK----- 302
L+ S+ P + E S W TQ D E + L+DRL E GT + K
Sbjct: 222 LEHSQRPAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSS 281
Query: 303 ---------------INELFVGKMKS---CIKCINVDYESSRVEDFWDIQL 335
+ ++F GK+ + C+ C+NV SSR E F D+ L
Sbjct: 282 SPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNV---SSREEAFTDLSL 329
>Hs22044541 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 525
Score = 56.2 bits (134), Expect = 8e-08
Identities = 44/178 (24%), Positives = 84/178 (46%), Gaps = 24/178 (13%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKEPL 257
G +N G TCY+N+ LQ +T + E+ N L +A ++ + P
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLS----REHSQNGCMLCTMQA-HITRALHNPG 135
Query: 258 DTTELTKSF--GWDTGDAFTQHDVQELNRILMD-----------RLEHRMKGTSVEGKIN 304
+ +++ G+ G Q D E +D +++H K T++ I+
Sbjct: 136 HVIQPSQALAAGFHRGK---QEDAHEFLMFTVDAMKKACLPGHKQVDHHAKDTTL---IH 189
Query: 305 ELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
++F G +S IKC++ S + + DI L+++ +++Q++ EQ ++ E +NGEN Y
Sbjct: 190 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAY 247
>Hs22044539 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 1074
Score = 56.2 bits (134), Expect = 8e-08
Identities = 44/178 (24%), Positives = 84/178 (46%), Gaps = 24/178 (13%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKEPL 257
G +N G TCY+N+ LQ +T + E+ N L +A ++ + P
Sbjct: 630 GLQNMGNTCYVNASLQCLTYTPPLANYMLS----REHSQNGCMLCTMQA-HITRALHNPG 684
Query: 258 DTTELTKSF--GWDTGDAFTQHDVQELNRILMD-----------RLEHRMKGTSVEGKIN 304
+ +++ G+ G Q D E +D +++H K T++ I+
Sbjct: 685 HVIQPSQALAAGFHRGK---QEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTL---IH 738
Query: 305 ELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
++F G +S IKC++ S + + DI L+++ +++Q++ EQ ++ E +NGEN Y
Sbjct: 739 QIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAY 796
>HsM19923759 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 55.1 bits (131), Expect = 2e-07
Identities = 54/218 (24%), Positives = 90/218 (40%), Gaps = 50/218 (22%)
Query: 189 DSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQ-IPTEDENPTNSVALALQRAF 247
+SK G G +N G TC++NS+LQ T+ R Q + D + ++ AL F
Sbjct: 259 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEF 318
Query: 248 Y-LLQT--SKEPLDT-------TELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGT 297
L+QT + P D T++ + G + Q D QE R L+D L + +
Sbjct: 319 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVG--YNQQDAQEFLRFLLDGLHNEVNRV 376
Query: 298 SV-----------------------------EGKINELFVGKMKSCIKCINVDYESSRVE 328
++ + +I +LFVG++KS + C + Y S+ +
Sbjct: 377 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFD 436
Query: 329 DFWDIQLNVKDMKNLQESFEQYIEVELMNGENQYAAQD 366
FWD+ L + + Y EV LM+ + +D
Sbjct: 437 PFWDLSLPI--------AKRGYPEVTLMDCMRLFTKED 466
>Hs22044534 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 530
Score = 55.1 bits (131), Expect = 2e-07
Identities = 43/180 (23%), Positives = 81/180 (44%), Gaps = 23/180 (12%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNS------------VALALQR 245
G +N G TCY+N+ LQ +T Y + E + + AL
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTTPLAN--YMLSREHSQTCHRHKGCMLCTMQAHITRALHN 138
Query: 246 AFYLLQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDR---LEHRMKGTSVEGK 302
+++Q S+ K + F V + + + R ++H K T++
Sbjct: 139 PGHVIQPSQALAAGFHRGKQ---EDAHEFLMFTVDAMKKACLPRHKQVDHHSKDTTL--- 192
Query: 303 INELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
I+++F G +S IKC++ S + + DI L+++ +++Q++ EQ ++ E +NGEN Y
Sbjct: 193 IHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAY 252
>CE09996 [O] KOG1866 Ubiquitin carboxyl-terminal hydrolase
Length = 1430
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/178 (29%), Positives = 84/178 (46%), Gaps = 15/178 (8%)
Query: 197 VGFKNQGATCYLNSLLQS-YHFTKLFRKLV--YQIPTEDENPTNSVAL--ALQRAFYLLQ 251
VG KN G TCY+N+++Q H L R+L+ I + N+ AL LQR F L
Sbjct: 274 VGMKNDGGTCYMNAMIQQLVHVPGLSRELIALQNIDPQLRWGDNTAALLCELQRVFAQLN 333
Query: 252 TSK-EPLDTTELTKSFGWDTG---DAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELF 307
++ + + L K F ++ + HD + IL+D+ ++ +K + F
Sbjct: 334 FAQCQAIVPEGLWKEFRFEPDMPLNTKQHHDAIDFYSILLDKCDNVLKKLELPPLFQNRF 393
Query: 308 VGKM---KSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
GK K C C + Y+S E+F I L + NL+E+ E ++ +M GEN Y
Sbjct: 394 FGKYSYEKICYGCWH-RYKSPD-EEFNCISLALSG-DNLEEALENFLAAHVMEGENAY 448
>CE09811 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 1230
Score = 55.1 bits (131), Expect = 2e-07
Identities = 49/169 (28%), Positives = 73/169 (42%), Gaps = 15/169 (8%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQI-PTEDENP-------TNSVALALQRAFYL 249
G N G CY+NS LQ + FR+L+Y P+E+ P + LALQ FY
Sbjct: 109 GLINGGNFCYVNSFLQVWFNVPEFRQLIYDFRPSENFVPPEAPRMNVQATMLALQDIFYT 168
Query: 250 LQTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRM----KGTSVEGKINE 305
LQT+ P + T+ T + G Q D QE + LE + G ++ +
Sbjct: 169 LQTT--PFNETDKTSNLGKLLRLNSEQQDSQEFGLKFFNALERCLPDHPNGKETLKRLKD 226
Query: 306 LFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVE 354
LF G+ + I C S R E + LN++ L ++ + Y E
Sbjct: 227 LFTGETCTRIVC-KCGQRSEREETAISLTLNIEGYCTLLDALDAYFGEE 274
>Hs20548613 [O] KOG1864 Ubiquitin-specific protease
Length = 370
Score = 54.3 bits (129), Expect = 3e-07
Identities = 48/210 (22%), Positives = 87/210 (40%), Gaps = 34/210 (16%)
Query: 196 FVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLLQTSKE 255
+ G N G TCY NS+LQ+ +F + FR+ V ++ S+ L F+ + T K+
Sbjct: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKK-ESLLTCLADLFHSIATQKK 96
Query: 256 PLDT-------TELTKSFGWDTGDAFTQHDVQELNRILM---------DRLEHRMKGTSV 299
+ T L K + D + Q D E L+ +R + + G
Sbjct: 97 KVGVIPPKKFITRLRKEN--ELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLP 154
Query: 300 EGKIN--------------ELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQE 345
G I+ E+F G + + +C+ + SS+ EDF D+ ++V+ ++
Sbjct: 155 NGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITH 214
Query: 346 SFEQYIEVELMNGENQYAAQD-HGLQDAQK 374
+ E + E +Y ++ Q+A K
Sbjct: 215 CLRGFSNTETLCSEYKYYCEECRSKQEAHK 244
>At4g17890_2 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 544
Score = 54.3 bits (129), Expect = 3e-07
Identities = 51/200 (25%), Positives = 92/200 (45%), Gaps = 20/200 (10%)
Query: 173 SIEDPTGVLWHNFLNYDSKKMTGF-VGFKNQGATCYLNSLLQSY-HFTKLFRKLV---YQ 227
S +P L++ F + + +TG G N G +C+LNS+ Q + H L L+ Y+
Sbjct: 1 SKNEPRKSLFYGF-RQEPEPVTGVGAGLWNLGNSCFLNSVFQCFTHTVPLIESLLSFRYE 59
Query: 228 IPTEDENPTNSVALALQRAFYLLQTSKEPLDTTELTKSFGWDTGDAFT-------QHDVQ 280
+P N V A++ Y ++ + P + + F +D + F+ Q D
Sbjct: 60 VPCHCGNEFFCVIRAIR---YHIEAALRP-ERCPIAPYFFFDNLNYFSPDFQRYQQEDAH 115
Query: 281 ELNRILMDRLEH-RMKGTSVEGKIN--ELFVGKMKSCIKCINVDYESSRVEDFWDIQLNV 337
E + +++LE TS G I ++F G++ S ++C N DY S E + L +
Sbjct: 116 EFLQAFLEKLEICGSDRTSFRGDITSQDVFSGRLISGLRCCNCDYVSETYEKSVGLSLEI 175
Query: 338 KDMKNLQESFEQYIEVELMN 357
+D+ L + E + VE ++
Sbjct: 176 EDVDTLGSALESFTRVEKLD 195
>Hs20540195 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 823
Score = 53.9 bits (128), Expect = 4e-07
Identities = 37/180 (20%), Positives = 78/180 (42%), Gaps = 17/180 (9%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTNSVALALQRAF--YLLQTSKE 255
G +N G TC+ N+ LQ +T Y + E ++ + ++ Q
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLAN--YMLSHEHSKTCHAEGFCMMCTMQAHITQALSN 169
Query: 256 PLDTTE----------LTKSFGW---DTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGK 302
P D + + + F + + F Q+ V + + ++ + T
Sbjct: 170 PGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTL 229
Query: 303 INELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
+ ++F G ++S +KC+N S + + DI L +K +++ ++ EQ+++ E ++GEN Y
Sbjct: 230 VCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSY 289
>Hs21361712 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 605
Score = 53.5 bits (127), Expect = 5e-07
Identities = 53/218 (24%), Positives = 89/218 (40%), Gaps = 50/218 (22%)
Query: 189 DSKKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQ-IPTEDENPTNSVALALQRAF 247
+SK G G +N G TC++NS+LQ T+ R Q + D + ++ AL F
Sbjct: 259 NSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEF 318
Query: 248 Y-LLQT--SKEPLDT-------TELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGT 297
L+QT + P D T++ + G + Q D QE R L+D L + +
Sbjct: 319 AKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVG--YNQQDAQEFLRFLLDGLHNEVNRV 376
Query: 298 SV-----------------------------EGKINELFVGKMKSCIKCINVDYESSRVE 328
++ + +I +LFVG++K + C + Y S+ +
Sbjct: 377 TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKGSLTCTDCGYCSTVFD 436
Query: 329 DFWDIQLNVKDMKNLQESFEQYIEVELMNGENQYAAQD 366
FWD+ L + + Y EV LM+ + +D
Sbjct: 437 PFWDLSLPI--------AKRGYPEVTLMDCMRLFTKED 466
>7295645 [O] KOG1868 Ubiquitin C-terminal hydrolase
Length = 857
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/207 (21%), Positives = 85/207 (40%), Gaps = 42/207 (20%)
Query: 191 KKMTGFVGFKNQGATCYLNSLLQSYHFTKLFRKLVYQ------IPTEDENPTNSVALALQ 244
+K G G +N G TC++NS++Q T+ + + + T+D+ + A +Q
Sbjct: 526 EKSEGLCGLRNIGNTCFMNSVIQCLSHTQELTRFLRSHHGSRSLSTKDQQILHEFAKLIQ 585
Query: 245 RAFYLLQTSKEPLDTTELTKSFGWDTG--DAFTQHDVQELNRILMDRLEHRMKGTSVEGK 302
+ + P+ EL ++F + Q D QE R +D L H + V+G+
Sbjct: 586 EMWTANVHTVTPM---ELKRAFSTKHRMYSDYNQQDAQEFLRFFLDSL-HSALNSGVKGE 641
Query: 303 ----------------------------INELFVGKMKSCIKCINVDYESSRVEDFWDIQ 334
+ +LFVG++KS +KC S + FWD+
Sbjct: 642 TLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLS 701
Query: 335 LNVKDMK--NLQESFEQYIEVELMNGE 359
+ + L+ + +I E+++G+
Sbjct: 702 VPLPSSSRCKLEACLDLFIREEVLDGD 728
>YMR223w [O] KOG1867 Ubiquitin-specific protease
Length = 471
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/217 (21%), Positives = 89/217 (40%), Gaps = 33/217 (15%)
Query: 191 KKMTGFVGFKNQGATCYLNSLLQSY-HFTKLFRKLVYQIPTED---ENPTNSVALALQRA 246
++ G G N G+TC+++S+LQ H R + QI + + +P + AL +
Sbjct: 131 ERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKI 190
Query: 247 FY----LLQTSKEPLDTTELTKSFG--------WDTGD---AFTQHDVQELNRILMDRLE 291
+ L T + +T + G W ++Q D E + +++++
Sbjct: 191 VHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIH 250
Query: 292 H-------------RMKGTSVEGKINELFVGKMKSCIKCINVDYES-SRVEDFWDIQLNV 337
R E ++ +F G ++S I C S + ++ F D+ L++
Sbjct: 251 QSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDI 310
Query: 338 KDMKNLQESFEQYIEVELMNGENQYAAQDHGLQDAQK 374
KD K L E + + + E + N + + + QDA K
Sbjct: 311 KDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIK 347
>Hs8394519 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/184 (21%), Positives = 84/184 (45%), Gaps = 12/184 (6%)
Query: 195 GFVGFKNQGATCYLNSLLQSY----HFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLL 250
G VG N G TC LNSL+Q + FT++ +++ +P + SV + +
Sbjct: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT--VPRGADEQRRSVPFQMLLLLEKM 110
Query: 251 QTSKEP-LDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVG 309
Q S++ + EL F QHD +L L + ++ ++ + ++ L+
Sbjct: 111 QDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTI 170
Query: 310 KMKSCIKCINVDYESSRVEDFWDIQLNV-----KDMKNLQESFEQYIEVELMNGENQYAA 364
++K + C++ ESSR + L++ K +K L+++ + + ++ +++
Sbjct: 171 RVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFC 230
Query: 365 QDHG 368
++ G
Sbjct: 231 ENCG 234
>Hs14776897 [O] KOG1863 Ubiquitin carboxyl-terminal hydrolase
Length = 372
Score = 50.8 bits (120), Expect = 3e-06
Identities = 39/184 (21%), Positives = 84/184 (45%), Gaps = 12/184 (6%)
Query: 195 GFVGFKNQGATCYLNSLLQSY----HFTKLFRKLVYQIPTEDENPTNSVALALQRAFYLL 250
G VG N G TC LNSL+Q + FT++ +++ +P + SV + +
Sbjct: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRIT--VPRGADEQRRSVPFQMLLLLEKM 110
Query: 251 QTSKEP-LDTTELTKSFGWDTGDAFTQHDVQELNRILMDRLEHRMKGTSVEGKINELFVG 309
Q S++ + EL F QHD +L L + ++ ++ + ++ L+
Sbjct: 111 QDSRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTI 170
Query: 310 KMKSCIKCINVDYESSRVEDFWDIQLNV-----KDMKNLQESFEQYIEVELMNGENQYAA 364
++K + C++ ESSR + L++ K +K L+++ + + ++ +++
Sbjct: 171 RVKDSLICVDCAMESSRNSSMLTLPLSLFDVDSKPLKTLEDALHCFFQPRELSSKSKCFC 230
Query: 365 QDHG 368
++ G
Sbjct: 231 ENCG 234
>SPAC13A11.04c [O] KOG1867 Ubiquitin-specific protease
Length = 449
Score = 50.1 bits (118), Expect = 5e-06
Identities = 49/191 (25%), Positives = 86/191 (44%), Gaps = 17/191 (8%)
Query: 195 GFVGFKNQGATCYLNSLLQSYHFTKLFRKLV---YQIPTEDENPTNSVALALQRAFYLLQ 251
G G +N GATC+++ +LQS L R L + T+ + PT + A+ F +
Sbjct: 143 GLRGIQNLGATCFMSVILQSILHNPLVRNLFFSGFHTSTDCKRPT-CMTCAIDDMFSSIY 201
Query: 252 TSKEPLDTTELTK--SFGWDTGDA---FTQHDVQELNRILMDRLEHRM-KGTSV--EGKI 303
SK T + W + ++Q D E L+D++ GTS+ I
Sbjct: 202 NSKNKSTFYGPTAVLNLMWKLSKSLCGYSQQDGHEFFVYLLDQMHTESGGGTSMPCTCPI 261
Query: 304 NELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQYA 363
+ +F G +K+ + C++ E V+ DI L++ + LQ E+++ E + QY+
Sbjct: 262 HRIFSGSLKNVVTCLDCKKERVAVDPLMDISLDINE-PTLQGCLERFVSKEKV----QYS 316
Query: 364 AQDHGLQDAQK 374
G ++A K
Sbjct: 317 CHSCGSKNAIK 327
>Hs22044528 [O] KOG1865 Ubiquitin carboxyl-terminal hydrolase
Length = 446
Score = 50.1 bits (118), Expect = 5e-06
Identities = 41/175 (23%), Positives = 78/175 (44%), Gaps = 23/175 (13%)
Query: 203 GATCYLNSLLQSYHFTKLFRKLVYQIPTEDENPTN------------SVALALQRAFYLL 250
G TCY+N+ LQ +T Y + E + + AL +++
Sbjct: 2 GNTCYVNASLQCLTYTPPLAN--YMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVI 59
Query: 251 QTSKEPLDTTELTKSFGWDTGDAFTQHDVQELNRILMDR---LEHRMKGTSVEGKINELF 307
Q S+ K + F V + + + R ++H K T++ I+++F
Sbjct: 60 QPSQALAAGFHRGKQ---EDAHEFLMFTVDAMKKACLPRHKQVDHHSKDTTL---IHQIF 113
Query: 308 VGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKNLQESFEQYIEVELMNGENQY 362
G +S IKC++ S + + DI L+++ +++Q++ EQ ++ E +NGEN Y
Sbjct: 114 GGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAY 168
>CE26241 [O] KOG1867 Ubiquitin-specific protease
Length = 664
Score = 49.3 bits (116), Expect = 9e-06
Identities = 49/206 (23%), Positives = 87/206 (41%), Gaps = 29/206 (14%)
Query: 198 GFKNQGATCYLNSLLQSYHFTKLFRKLVYQIPT---------EDENPTNSVALALQRAFY 248
G +N G TC++N++LQ+ FR+ + + + E +N N L +
Sbjct: 379 GMRNVGNTCFMNAVLQALASISEFREYIMSLSSLEDYIHDEKEPKNGGNYCYLTDEYRKL 438
Query: 249 LLQTS----KEPLDTTELTKSF--GWDTGDAFTQHDVQELNRILMDRLEHRM-KGTSVEG 301
L+ S +EP E ++F F QHD E R MD L M K + G
Sbjct: 439 LISQSARSFREPTAPNEFREAFISVCPRFRGFRQHDSHEFMRYFMDSLHTEMRKCRKLPG 498
Query: 302 -------KINELFVGKMKSCIKCINVDYESSRVEDFWDIQLNVKDMKN-----LQESFEQ 349
I++ F G ++S + C S+++++F D+ L++ +N L +
Sbjct: 499 MPDDKHTPISKYFEGTLQSSVICQTCRNCSNKIDEFMDLSLDIPAQRNASKVRLSDCLST 558
Query: 350 YIEVELM-NGENQYAAQDHGLQDAQK 374
+ ++E++ GE A+ Q K
Sbjct: 559 FFKLEMLEKGEKPECAKCKTKQTCSK 584
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,414,025
Number of Sequences: 60738
Number of extensions: 1055044
Number of successful extensions: 2736
Number of sequences better than 1.0e-05: 38
Number of HSP's better than 0.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2671
Number of HSP's gapped (non-prelim): 41
length of query: 375
length of database: 30,389,216
effective HSP length: 108
effective length of query: 267
effective length of database: 23,829,512
effective search space: 6362479704
effective search space used: 6362479704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)