ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3471 good AD KOG2809 Cell cycle control, cell division, chromosome partitioning Telomerase elongation inhibitor/RNA maturation protein PINX1
r_klactIII3471 good AD KOG2809 RNA processing and modification Telomerase elongation inhibitor/RNA maturation protein PINX1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3471 1222717 1221905 -271
(271 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR280c [AD] KOG2809 Telomerase elongation inhibitor/RNA maturat... 253 3e-67
Hs16975486 [AD] KOG2809 Telomerase elongation inhibitor/RNA matu... 72 6e-13
SPAC890.05 [AD] KOG2809 Telomerase elongation inhibitor/RNA matu... 72 1e-12
CE03704 [AD] KOG2809 Telomerase elongation inhibitor/RNA maturat... 55 1e-07
Hs20551919 [AD] KOG2809 Telomerase elongation inhibitor/RNA matu... 52 9e-07
>YGR280c [AD] KOG2809 Telomerase elongation inhibitor/RNA maturation protein
PINX1
Length = 271
Score = 253 bits (645), Expect = 3e-67
Identities = 141/272 (51%), Positives = 164/272 (59%), Gaps = 3/272 (1%)
Query: 1 MGLAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVP-DSTTSHIKVSI 59
MGLAA R KQRFGLDPRNT WSN+TSRFGH+ LEK GWKPG GLGL P +S TSHIKVSI
Sbjct: 1 MGLAATRTKQRFGLDPRNTAWSNDTSRFGHQFLEKFGWKPGMGLGLSPMNSNTSHIKVSI 60
Query: 60 XXXXXXXXXXXXXXXXXXXFDSGECTGLDVFQRLLGRLNGNEQTISDELDKQRTDNIING 119
FD+GEC GLDVFQR+LGRLNG E IS+ELD QR II+G
Sbjct: 61 KDDNVGLGAKLKRKDKKDEFDNGECAGLDVFQRILGRLNGKESKISEELDTQRKQKIIDG 120
Query: 120 KWGIHFVKGEVLASTWDAENKQLISYSMGKKRPVEGSSDSEVSDRXXXXXXXXXXXXXXX 179
KWGIHFVKGEVLASTWD + +L +YS KKR EG DSE D
Sbjct: 121 KWGIHFVKGEVLASTWDPKTHKLRNYSNAKKRKREG-DDSEDED-DDDKEDKDSDKKKHK 178
Query: 180 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXHSKDTNEITRDQMLKPRDSAAVVPDAV 239
++ T E + LK +SA+ +PDAV
Sbjct: 179 KHKKHKKDKKKDKKDKKEHKKHKKEEKRLKKEKRAEKTKETKKTSKLKSSESASNIPDAV 238
Query: 240 STRLSVRAKWIRQKRAAVMDAKALNEIFMVTD 271
+TRLSVR+KWI+QKRAA+MD+KALNEIFM+T+
Sbjct: 239 NTRLSVRSKWIKQKRAALMDSKALNEIFMITN 270
>Hs16975486 [AD] KOG2809 Telomerase elongation inhibitor/RNA maturation protein
PINX1
Length = 328
Score = 72.4 bits (176), Expect = 6e-13
Identities = 51/167 (30%), Positives = 75/167 (44%), Gaps = 17/167 (10%)
Query: 3 LAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVPDSTTSHIKVSIXXX 62
LA R KQ++ +DP+NT WSN+ S+FG + LEK+GW G GLG T HIKV +
Sbjct: 4 LAERRRKQKWAVDPQNTAWSNDDSKFGQRMLEKMGWSKGKGLGAQEHGATDHIKVQVKNN 63
Query: 63 XXXXXXXXXXXXXXXXFDSGECTGLDVFQRLLGRLN---GNEQTISDELDKQRTDNIIN- 118
+ D F +LL LN G E T S + ++++ ++
Sbjct: 64 HLGLGATINN-------EDNWIAHQDDFNQLLAELNTCHGQETTDSSDKKEKKSFSLEEK 116
Query: 119 ---GKWGIH---FVKGEVLASTWDAENKQLISYSMGKKRPVEGSSDS 159
K +H F KG+ L+S + + KK P +S S
Sbjct: 117 SKISKNRVHYMKFTKGKDLSSRSKTDLDCIFGKRQSKKTPEGDASPS 163
>SPAC890.05 [AD] KOG2809 Telomerase elongation inhibitor/RNA maturation protein
PINX1
Length = 284
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/166 (29%), Positives = 75/166 (44%), Gaps = 28/166 (16%)
Query: 1 MGLAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVPDSTTSHIKVSIX 60
MGLA + KQ+ G+DPRN+ W+ +T+R G K L GW G+GLG +IKVS+
Sbjct: 1 MGLAGVKKKQQIGVDPRNSKWAKDTNRLGFKLLSSYGWVNGNGLGEKQHGRIHNIKVSLK 60
Query: 61 XXXXXXXXXXXXXXXXXXFDSGECTGLDVFQRLLGRLNGNEQTISDELDKQRTDNIINGK 120
+ E +GL F + GRLNG+E
Sbjct: 61 DDTLGIGAKAT--------NDLEWSGLGEFNAIFGRLNGDESA----------------- 95
Query: 121 WGIHFVKGEVLASTWD---AENKQLISYSMGKKRPVEGSSDSEVSD 163
+G++ K +V T++ A K L S + ++ + G+ SE S+
Sbjct: 96 YGVYAEKAKVQQLTYERQSANEKGLKSLELSRRFVLGGTFTSEFSE 141
>CE03704 [AD] KOG2809 Telomerase elongation inhibitor/RNA maturation protein
PINX1
Length = 339
Score = 55.1 bits (131), Expect = 1e-07
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 5/110 (4%)
Query: 3 LAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVPDSTTSHIKVSIXXX 62
LA + KQ+ +DP+N TW N+ + K +EK+GW G GLG +K+
Sbjct: 4 LAEPKRKQKISIDPQNLTWKNDDQKLSKKLMEKMGWSEGDGLGRNRQGNADSVKLK---- 59
Query: 63 XXXXXXXXXXXXXXXXFDSGECTGLDVFQRLLGRLNGNEQTISDELDKQR 112
+DS + D F LL LN N++ ++ ++++
Sbjct: 60 -ANTSGRGLGADKMADYDSTWISHHDDFADLLAALNKNKEQEPEQTEEEK 108
>Hs20551919 [AD] KOG2809 Telomerase elongation inhibitor/RNA maturation
protein PINX1
Length = 483
Score = 52.0 bits (123), Expect = 9e-07
Identities = 23/57 (40%), Positives = 34/57 (59%)
Query: 3 LAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVPDSTTSHIKVSI 59
LA + KQ++ ++ +NT WSN S+FG + LEK+ W G GLG+ IKV +
Sbjct: 4 LAEQQQKQKWAVNTQNTAWSNADSKFGQRILEKMEWSKGRGLGVQEQGGPDDIKVQV 60
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.131 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,031,121
Number of Sequences: 60738
Number of extensions: 398015
Number of successful extensions: 772
Number of sequences better than 1.0e-05: 5
Number of HSP's better than 0.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 762
Number of HSP's gapped (non-prelim): 7
length of query: 271
length of database: 30,389,216
effective HSP length: 105
effective length of query: 166
effective length of database: 24,011,726
effective search space: 3985946516
effective search space used: 3985946516
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)