ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3479 good YU KOG2171 Intracellular trafficking, secretion, and vesicular transport Karyopherin (importin) beta 3
r_klactIII3479 good YU KOG2171 Nuclear structure Karyopherin (importin) beta 3
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3479 1226402 1223133 -1090
(1090 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YMR308c [YU] KOG2171 Karyopherin (importin) beta 3 1309 0.0
SPCC1840.03 [YU] KOG2171 Karyopherin (importin) beta 3 642 0.0
7296831 [YU] KOG2171 Karyopherin (importin) beta 3 440 e-123
Hs21361131 [YU] KOG2171 Karyopherin (importin) beta 3 399 e-110
HsM4504909 [YU] KOG2171 Karyopherin (importin) beta 3 395 e-109
At5g19820 [YU] KOG2171 Karyopherin (importin) beta 3 360 9e-99
CE26971 [YU] KOG2171 Karyopherin (importin) beta 3 298 2e-80
Hs16161756 [YU] KOG2171 Karyopherin (importin) beta 3 114 6e-25
At4g27640 [YU] KOG2171 Karyopherin (importin) beta 3 99 3e-20
SPBC14F5.03c [YU] KOG2171 Karyopherin (importin) beta 3 71 8e-12
YER110c [YU] KOG2171 Karyopherin (importin) beta 3 71 1e-11
Hs14756038 [YU] KOG2171 Karyopherin (importin) beta 3 63 3e-09
Hs18874099 [YU] KOG2171 Karyopherin (importin) beta 3 59 5e-08
At2g16950 [YU] KOG2023 Nuclear transport receptor Karyopherin-be... 56 3e-07
7295355 [YU] KOG2023 Nuclear transport receptor Karyopherin-beta... 56 3e-07
SPAC2F3.06c [YU] KOG2023 Nuclear transport receptor Karyopherin-... 55 8e-07
>YMR308c [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1089
Score = 1309 bits (3388), Expect = 0.0
Identities = 665/1092 (60%), Positives = 826/1092 (74%), Gaps = 5/1092 (0%)
Query: 1 MSVLPDEVNSTLVKLLQGFASPDNAIRSAAEDALNNNWITPEHIEVLLMFLAEQSAYSDD 60
MS LP+EVN TL++++Q FASPDN IRS AE AL+ WIT +IE LL FLAEQ+A+S D
Sbjct: 1 MSALPEEVNRTLLQIVQAFASPDNQIRSVAEKALSEEWITENNIEYLLTFLAEQAAFSQD 60
Query: 61 LTTAGLSAVLFRKLALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRH 120
T A LSAVLFRKLAL+APPSSK +I++KNITHI KE L QIR +LLKGF+S+R ++IRH
Sbjct: 61 TTVAALSAVLFRKLALKAPPSSKLMIMSKNITHIRKEVLAQIRSSLLKGFLSERADSIRH 120
Query: 121 KLSDAIAECAXXXXXXXXXXXQTLFEAIKNTDPNFRESSFRIFSSMPHLINSIDINHALP 180
KLSDAIAEC Q L E++K+ +PNFRESSFRI +++P+LI ++DIN LP
Sbjct: 121 KLSDAIAECVQDDLPAWPELLQALIESLKSGNPNFRESSFRILTTVPYLITAVDINSILP 180
Query: 181 IFESGFTDPSDEVKIAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALA 240
IF+SGFTD SD VKIAAVTAFVGYFKQLPK+ W+ DD KD+ALA
Sbjct: 181 IFQSGFTDASDNVKIAAVTAFVGYFKQLPKSEWSKLGILLPSLLNSLPRFLDDGKDDALA 240
Query: 241 AVFESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMC 300
+VFESLIELVELAPKLFKDMFDQIIQF DMVIKNKDLEP ARTTALELLTVFSE APQMC
Sbjct: 241 SVFESLIELVELAPKLFKDMFDQIIQFTDMVIKNKDLEPPARTTALELLTVFSENAPQMC 300
Query: 301 KNNQNYAQSVVLDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKL 360
K+NQNY Q++V+ TL+MMTEVSIDDD A EW TYD ARQALDRVALKL
Sbjct: 301 KSNQNYGQTLVMVTLIMMTEVSIDDDDAAEW-IESDDTDDEEEVTYDHARQALDRVALKL 359
Query: 361 NGKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDD 420
G+YLAAPLFQ+LQQMITS+EWRERFAA+MALSSAAEGC DVL+ EI KIL+MV+PLI+D
Sbjct: 360 GGEYLAAPLFQYLQQMITSTEWRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLIND 419
Query: 421 PHPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFS 480
PHPRVQYGCCNVLGQISTDF+P IQ T+H++ILPALISKLTS RVQTHAAAALVNFS
Sbjct: 420 PHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFS 479
Query: 481 EQATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKYYDTLMPLL 540
E A++ I+EPY KLYVQEQALTTIAFIAEAA+ KFIKYYDTLMPLL
Sbjct: 480 EFASKDILEPYLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAAKNKFIKYYDTLMPLL 539
Query: 541 INVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNEGIQDDDPL 600
+NVL+ + ++ VLKGKCMEC+TLI AVGKEKF +SQELI + + QN I +DD L
Sbjct: 540 LNVLKVN-NKDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDIDEDDAL 598
Query: 601 KTYLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSLIEEEEAANYQQYTDWDVV 660
++YLEQSWSR+CRIL +DF TAKATQDV LIEEEEAAN+QQY DWDVV
Sbjct: 599 RSYLEQSWSRICRILGDDFVPLLPIVIPPLLITAKATQDVGLIEEEEAANFQQYPDWDVV 658
Query: 661 QIQGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVPSIDFYLHDGVR 720
Q+QGKHIAIHTSVLDDKV+AMELLQ YAT+L+ FA YVKE++ E+A+PS+DFYLHDGVR
Sbjct: 659 QVQGKHIAIHTSVLDDKVSAMELLQSYATLLRGQFAVYVKEVMEEIALPSLDFYLHDGVR 718
Query: 721 ARGATLIPALFTSLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVTKSYHYALVDCL 780
A GATLIP L + L++A G N+ ++ LW AS+KLI G++SEPMPE+T+ YH +LV+ +
Sbjct: 719 AAGATLIPILLSCLLAATGTQNEELVLLWHKASSKLIGGLMSEPMPEITQVYHNSLVNGI 778
Query: 781 GIVGNNGLNQEQLSQFTQGVNNNLTDVYERTKSRXXXXXXXXXXXXXXXXXXXXXXXXXX 840
++G+N L+++QL+ FT+GV+ NLTD YER + R
Sbjct: 779 KVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDR-HGDGDEYNENIDEEEDFTDEDLLDE 837
Query: 841 INKSLAAVFKSAGVSYLQQFQTLWPIIHSYLQETEVFILLFALIAIADMIEYTGDNSAPF 900
INKS+AAV K+ YL+ + +WP+I+++L + E +++FAL+ I D+I+Y G+ +A
Sbjct: 838 INKSIAAVLKTTNGHYLKNLENIWPMINTFLLDNEPILVIFALVVIGDLIQYGGEQTASM 897
Query: 901 KQHFVQKIKECLTFPEPSIRQGTAYLLGVCAQYAPNTYSDICLGSLETLFQIVNMPESRS 960
K F+ K+ ECL P+ IRQ +Y++GVCAQYAP+TY+D+C+ +L+TL QIV+ P S+
Sbjct: 898 KNAFIPKVTECLISPDARIRQAASYIIGVCAQYAPSTYADVCIPTLDTLVQIVDFPGSKL 957
Query: 961 EDNVNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHDEECAAFNYRMLAQLID 1020
E+N +S+ENAS AIAKIL +Y S+IPN + YTANW KT P I D+E A+FNY+ L+QLI+
Sbjct: 958 EENRSSTENASAAIAKILYAYNSNIPNVDTYTANWFKTLPTITDKEAASFNYQFLSQLIE 1017
Query: 1021 HNSPVI--QGNTAEIVDYVIQALHQKSIGGKNATAVVESAKKLLSTIPQEQASALLQRYP 1078
+NSP++ Q N + +VD VIQAL+++S+ + V+ S KKLL +P A A+ RYP
Sbjct: 1018 NNSPIVCAQSNISAVVDSVIQALNERSLTEREGQTVISSVKKLLGFLPSSDAMAIFNRYP 1077
Query: 1079 PEIMQTIHKWFA 1090
+IM+ +HKWFA
Sbjct: 1078 ADIMEKVHKWFA 1089
>SPCC1840.03 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1095
Score = 642 bits (1657), Expect = 0.0
Identities = 375/1085 (34%), Positives = 585/1085 (53%), Gaps = 19/1085 (1%)
Query: 2 SVLPDEVNSTLVKLLQGFASPDNAIRSAAEDALNNNWITPEHIEVLLMFLAEQSAYSDDL 61
S P EV S L+ L+QG +SPDN +R+ AE +L+++WI+ + ++LL LA + S+D
Sbjct: 3 SGFPPEVLSPLLNLVQGLSSPDNTVRNDAEKSLSSDWIS-QRADLLLNGLAILAYQSEDP 61
Query: 62 TTAGLSAVLFRKLALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHK 121
VL R+++ R P + + +I++ SK++L+ LL F+ + +R+K
Sbjct: 62 AVRSFCLVLCRRISFRTLPGDSELEVFSSISNESKQSLQS---QLLACFVKESVPTVRNK 118
Query: 122 LSDAIAECAXXXXXXXXXXXQ---TLFEAIKNTDPNFRESSFRIFSSMPHLINSIDINHA 178
L D IAE A + +F A+ + D +FRES FR +S+P L++ D +
Sbjct: 119 LCDTIAEIARSIYDCQGEWPELINVIFNAVNSPDESFRESVFRTITSLPRLLSGQD-SAV 177
Query: 179 LPIFESGFTDPSDEVKIAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEA 238
P+F +G DPS V+I+A A+ + ++ D +
Sbjct: 178 TPLFTTGLADPSIRVRISAARAYSAVILESKQSTRDQVIPLLPSLMNILPPLQQDRDSDN 237
Query: 239 LAAVFESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQ 298
LA ++ E+ E+ PKLFK +F+ +I F +IK+K+L+ SAR ALELL FSE AP
Sbjct: 238 LADCLMAITEIAEVFPKLFKPIFESVIAFGLGIIKDKELDNSARQAALELLVCFSEGAPA 297
Query: 299 MCKNNQNYAQSVVLDTLVMMTEVSID-DDQAIE---WQXXXXXXXXXXXXTYDMARQALD 354
MC+ + +Y +VL L++MT+V+ D +D+A E W + +A QA+D
Sbjct: 298 MCRKSSDYTDQLVLQCLLLMTDVAGDPEDEAEELQEWLNTDDLDQDESDANHVVAEQAMD 357
Query: 355 RVALKLNGKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMV 414
R++ KL GK + P F +L ++I S +W ER AALMA+SS AEG ++ E+ ++L+MV
Sbjct: 358 RLSRKLGGKTILPPSFTWLPRLIPSQKWSERHAALMAISSIAEGAEKLMKKELSRVLDMV 417
Query: 415 VPLIDDPHPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAA 474
+PL+ DPHPRV++ CN +GQ+STDFAP +Q +IL AL+ L S RVQ HAAA
Sbjct: 418 LPLLADPHPRVRWAACNAVGQMSTDFAPDMQVKYPSRILEALVPVLESPE-SRVQAHAAA 476
Query: 475 ALVNFSEQATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKYYD 534
A+VNFSE+A ++EPY K YVQEQA+TTIA +A+AA KKF KY+D
Sbjct: 477 AMVNFSEEADNKVLEPYLDDILQRLLTLLQSPKRYVQEQAVTTIATVADAAAKKFEKYFD 536
Query: 535 TLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNEGI 594
+MPLL NVL+ G E R L+GK MEC+TLIALAVGK++F SQELIQ+ Q
Sbjct: 537 AIMPLLFNVLQQADGKEFRTLRGKTMECATLIALAVGKQRFLPVSQELIQILGNIQMGIT 596
Query: 595 QDDDPLKTYLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSLIEEE-EAANYQQ 653
DDP +YL +W R+CR+L DF A + D ++I++E + + Y +
Sbjct: 597 DSDDPQASYLISAWGRICRVLGSDFVPFLSSVMPPLLVAATSKPDFTIIDDEVDESKYSE 656
Query: 654 YTDWDVVQIQGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVPSIDF 713
W+ + + G+ + I TS L+DK TA E+L YA LK+ F YV E+LT V +P + F
Sbjct: 657 QDGWEFIPVHGQQVGIRTSTLEDKCTATEMLVCYAAELKADFDPYVNEVLTSVVLPGLKF 716
Query: 714 YLHDGVRARGATLIPALFTSLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVTKSYH 773
+ HDGVR+ IP L + + A +D V +LW+ KL+ I +EP E+ Y
Sbjct: 717 FFHDGVRSACCKCIPQLLNARILASNRDPAKVNELWEPILRKLLDHIQNEPSVEMLADYF 776
Query: 774 YALVDCLGIVGNNGLNQEQLSQFTQGVNNNL----TDVYERTKSRXXXXXXXXXXXXXXX 829
L I G N L+ + V+ L + V +R +
Sbjct: 777 ECFYQSLEISGLN-LSPSSMEALVAAVDLQLKGFISRVQQREEEAKNGDIDIEEDEDMIL 835
Query: 830 XXXXXXXXXXXINKSLAAVFKSAGVSYLQQFQTLWPIIHSYLQETEVFILLFALIAIADM 889
INK+ + V K ++ ++ L P + +L + +AL + D+
Sbjct: 836 AVENDQNLLNEINKTFSVVLKIHKTAFCPFWERLLPYMDGFLSGNDTVAKQWALCMMDDL 895
Query: 890 IEYTGDNSAPFKQHFVQKIKECLTFPEPSIRQGTAYLLGVCAQYAPNTYSDICLGSLETL 949
IE+TG +S +K HF+ + E + EP IRQ +Y +GV AQ+ Y++IC +L L
Sbjct: 896 IEFTGPDSWNYKDHFLPYLAEGIQSSEPEIRQAASYGIGVAAQHGGELYAEICSSALPAL 955
Query: 950 FQIVNMPESRSEDNVNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHDEECAA 1009
F+++ +P++R E+ + ++EN AI KI + + ++ W+ T PV HDE+ A
Sbjct: 956 FKMLELPDARDEEQIYATENICVAICKICRFCSQRVQDLDKVVTYWINTLPVTHDEDDAP 1015
Query: 1010 FNYRMLAQLIDHNSPVIQGNTAEIVDYVIQALHQKSIGGKNATAVVESAKKLLSTIPQEQ 1069
+ Y LA+L++ N + I+ + + + G+ T ++E++K L+ P +Q
Sbjct: 1016 YAYTFLAELMEQNHVAVASQMPTIITILAETFASGVLRGRTLTRLMEASKVYLARFPADQ 1075
Query: 1070 ASALL 1074
++++
Sbjct: 1076 VNSVI 1080
>7296831 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1105
Score = 440 bits (1131), Expect = e-123
Identities = 315/1109 (28%), Positives = 515/1109 (46%), Gaps = 67/1109 (6%)
Query: 14 KLLQGFASPDNAIRSAAEDALNNNWITPEHIEVLLMFLAEQSAYSDDLTTAGLSAVLFRK 73
+LL S DN +R AE+A NN ++ E L+ + S++ ++AVL R+
Sbjct: 10 QLLASLLSTDNDVRQQAEEAYNN--LSRELKVTHLLGNIQNGQQSEEARQ--MAAVLLRR 65
Query: 74 LALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXX 133
L T + E+ Q+ +L + +R K+ + +AE A
Sbjct: 66 LF--------TTEFFDFYKGLPAESQNQLLQQILLAVQQEVTPQLRRKICEVVAEVARNL 117
Query: 134 XXXXXXXX-----QTLFEAIKNTDPNFRESSFRIFSSMPHLINSID------INHALPIF 182
Q LF+ + P +ES+ RIFSS+P + + + I L
Sbjct: 118 IDEDCNNQWPDILQFLFQCANSPTPQLQESALRIFSSVPSIFGNQEAQYIDLIKQMLAKS 177
Query: 183 ESGFTDPSDEVK-IAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAA 241
+DP V+ + AV AF+ Y + +N A + + + +
Sbjct: 178 MDAGSDPEVRVQAVRAVGAFILYHDK--ENETAIHKHFADMLPRMIHITGETIEAQDDQS 235
Query: 242 VFESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMC- 300
+ + LIE+ E PK + + I + V ++D E S R LE++ +E AP M
Sbjct: 236 LLKLLIEMTENCPKFLRPQLEFIFEVCMKVFSSQDFEDSWRHLVLEVMVSLAENAPSMIR 295
Query: 301 KNNQNYAQSVVLDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKL 360
K Y +++ L MMT+ +DDD+ W +A +LDR+A L
Sbjct: 296 KRADKYIVALIPLILHMMTD--LDDDE--NWSTADVVDDDDHSDNNVIAESSLDRLACGL 351
Query: 361 NGKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDD 420
GK + + L M+ ++W+ RFAALMA+S+ EGC + +D+++ V+ + D
Sbjct: 352 GGKIVLPLVMNALPVMLGHADWKHRFAALMAISAIGEGCHKQMEAILDEVMSGVLNFLSD 411
Query: 421 PHPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFS 480
PHPRV+Y CN +GQ+STDFA + H +++P L+S L RVQ HA AALVNFS
Sbjct: 412 PHPRVRYAACNAIGQMSTDFAQTFEKKFHSQVIPGLLSLLDDVENPRVQAHAGAALVNFS 471
Query: 481 EQATQSIMEPYXXXXXXXXXXXXXX--------XKLYVQEQALTTIAFIAEAAEKKFIKY 532
E ++I+ Y V EQ +TTIA +A+ E +F+ Y
Sbjct: 472 EDCPKNILTRYLDGIMAKLETILNSKFKELVEKGNKLVLEQVVTTIASVADTCESEFVAY 531
Query: 533 YDTLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNE 592
YD LMP L +++ + R+L+GK +EC +LI LAVG+EKF + E++ + + E
Sbjct: 532 YDRLMPCLKFIIQNANSDDLRMLRGKTIECVSLIGLAVGREKFIGDAGEVMDMLLVNHTE 591
Query: 593 G--IQDDDPLKTYLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSLIEEEEAAN 650
G + DDDP +YL +W+R+C+IL + F TA +V++++ +E +
Sbjct: 592 GGELADDDPQTSYLITAWARMCKILGKQFEQYLPLVMGPVMRTATMKPEVAMLDNDEVED 651
Query: 651 YQQYTDWDVVQI-QGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVP 709
DW + + + ++ AI T+ +DDK +A E+L YA LK FA Y ++++ ++ +P
Sbjct: 652 IDGDVDWSFINLGEQQNFAIRTAGMDDKASACEMLVCYARELKEGFAEYAEDVVRQM-LP 710
Query: 710 SIDFYLHDGVRARGATLIPALFTSLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVT 769
+ FY HDGVR A +P L L A + + +W +L+ I++EP P+V
Sbjct: 711 MLKFYFHDGVRTAAAESLPYL---LDCAKIKGPQYLEGMWMFICPELLKVIVTEPEPDVQ 767
Query: 770 KSYHYALVDCLGIVGNNGLNQEQLSQFTQGVNNNLTDVYERTKSRXXXXXXXXXXXXXXX 829
+L C+ +G N LN++ + Q + +N + + +ER R
Sbjct: 768 SELLNSLAKCIETLGPNCLNEDAMKQVLEIINKYVLEHFERADKRLAARNEEDYDDGVEE 827
Query: 830 XXXXXXXXXXXINKSLA----AVFKSAGVSYLQQFQTLWPIIHSYLQETE-VFILLFALI 884
I + A+F++ +L F+ + P L+ + V + L
Sbjct: 828 ELAEQDDTDVYILSKIVDITHALFQTNKAQFLPAFEQVAPHFVKLLEPSRPVADRQWGLC 887
Query: 885 AIADMIEYTGDNSAPFKQHFVQKIKECLTFPEPSIRQGTAYLLGVCAQYAPNTYSDICLG 944
D+IE+ G AP++Q F + + + P +RQ AY GV Q+A ++ C
Sbjct: 888 VFDDLIEFCGPACAPYQQIFTPALVQYVCDKAPEVRQAAAYGCGVLGQFAGEQFAHTCAQ 947
Query: 945 SLETLFQIVNMPESRSEDNVNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHD 1004
+ L Q++N P++R +N++ +ENA A AKIL S++ N ++ W PV D
Sbjct: 948 IIPLLVQVINDPKAREIENISPTENAISAFAKILKYNNSALSNVDELIGVWFSWLPVSED 1007
Query: 1005 EECAAFNYRMLAQLIDHNSPVI----QGNTAEIVDYVIQALHQKSIGGKNATAV------ 1054
E AA Y L LI+ N PVI GN IV + ++ K + ++AT
Sbjct: 1008 SEEAAHIYGYLCDLIEGNHPVILGANNGNLPRIVSIIAESFCTKVVEAQSATGTRMLTIV 1067
Query: 1055 --VESAKKLL----STIPQEQASALLQRY 1077
VES +++ ST+ EQ AL Y
Sbjct: 1068 KQVESNPEVMAACASTLSPEQQQALQDAY 1096
>Hs21361131 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1097
Score = 399 bits (1024), Expect = e-110
Identities = 288/1091 (26%), Positives = 500/1091 (45%), Gaps = 67/1091 (6%)
Query: 15 LLQGFASPDNAIRSAAEDALNNNWITPEHIEVLLMFLAEQSAYSDDLTTAGLSAVLFRKL 74
LL SPDN +R AE+ N P ++ + A ++ + + ++AVL R+L
Sbjct: 14 LLGNLLSPDNVVRKQAEETYEN---IPGQSKITFLLQAIRNTTAAE-EARQMAAVLLRRL 69
Query: 75 ALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXXX 134
A + + T I E L I+ + +++R K+ D AE A
Sbjct: 70 LSSAFDEVYPALPSDVQTAIKSELLMIIQ--------METQSSMRKKVCDIAAELARNLI 121
Query: 135 XXXXXXX-----QTLFEAIKNTDPNFRESSFRIFSSMPHLINSIDINHALPIFESGFTDP 189
+ LF+++ + + RE++ IF + P + + H L + +
Sbjct: 122 DEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQ-QHYLDVIKRMLVQC 180
Query: 190 SDE--------VKIAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAA 241
+ + A AF+ L + +DS + +
Sbjct: 181 MQDQEHPSIRTLSARATAAFI-----LANEHNVALFKHFADLLPGFLQAVNDSCYQNDDS 235
Query: 242 VFESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMCK 301
V +SL+E+ + PK + + +Q + + + L R ALE++ SE A M +
Sbjct: 236 VLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLR 295
Query: 302 NNQNYAQSVVLDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKLN 361
+ N + L MM ++ D+D W ALDR+A L
Sbjct: 296 KHTNIVAQTIPQMLAMMVDLEEDED----WANADELEDDDFDSNAVAGESALDRMACGLG 351
Query: 362 GKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDP 421
GK + + + + QM+ + +W+ R A LMALS+ EGC + +++I+ V+ + DP
Sbjct: 352 GKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDP 411
Query: 422 HPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFSE 481
HPRV+Y CN +GQ++TDFAP Q HEK++ AL+ + RVQ HAAAAL+NF+E
Sbjct: 412 HPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTE 471
Query: 482 QATQSIMEPY---------XXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKY 532
+S++ PY KL V EQ +T+IA +A+ AE+KF+ Y
Sbjct: 472 DCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKL-VLEQVVTSIASVADTAEEKFVPY 530
Query: 533 YDTLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNE 592
YD MP L +++ E R+L+GK +EC +LI LAVGKEKF + +++QL + Q +
Sbjct: 531 YDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTD 590
Query: 593 --GIQDDDPLKTYLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSLIEEEEAAN 650
++DDDP +Y+ +W+R+C+IL ++F +TA +V+L++ ++ N
Sbjct: 591 FNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMEN 650
Query: 651 YQQYTDWDVVQI-QGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVP 709
W+ V + + I T+ L++K TA ++L YA LK F Y ++++ ++ VP
Sbjct: 651 MSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVV-KLMVP 709
Query: 710 SIDFYLHDGVRARGATLIPALFTSLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVT 769
+ FY HDGVR A +P L L A + + + Q+W + LI I +EP +V
Sbjct: 710 LLKFYFHDGVRVAAAESMPLL---LECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVL 766
Query: 770 KSYHYALVDCLGIVGNNGLNQEQLSQFTQGVNNNLTDVYE----RTKSRXXXXXXXXXXX 825
++ C+ ++G+ LN E + + L + ++ R R
Sbjct: 767 SEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEE 826
Query: 826 XXXXXXXXXXXXXXXINKSLAAVFKSAGVSYLQQFQTLWPIIHSYLQETEVF-ILLFALI 884
++ L ++F S L F+ L P+I + + + + L
Sbjct: 827 SLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLC 886
Query: 885 AIADMIEYTGDNSAPFKQHFVQKIKECLTFPEPSIRQGTAYLLGVCAQYAPNTYSDICLG 944
D+IE+ S + ++F++ + + + P +RQ AY LGV AQY + Y C
Sbjct: 887 IFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTE 946
Query: 945 SLETLFQIVNMPESRSEDNVNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHD 1004
+L L +++ +S++++NVN++EN A+ KI+ + N E+ +WL P+ D
Sbjct: 947 ALPLLVRVIQSADSKTKENVNATENCISAVGKIM-KFKPDCVNVEEVLPHWLSWLPLHED 1005
Query: 1005 EECAAFNYRMLAQLIDHNSPVIQG----NTAEIVDYVIQALHQKSIGGKNATAVVESAKK 1060
+E A + L LI+ N P++ G N +I + + ++I ++ AK+
Sbjct: 1006 KEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHED-----PCAKR 1060
Query: 1061 LLSTIPQEQAS 1071
L + + Q Q S
Sbjct: 1061 LANVVRQVQTS 1071
>HsM4504909 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1097
Score = 395 bits (1016), Expect = e-109
Identities = 287/1091 (26%), Positives = 498/1091 (45%), Gaps = 67/1091 (6%)
Query: 15 LLQGFASPDNAIRSAAEDALNNNWITPEHIEVLLMFLAEQSAYSDDLTTAGLSAVLFRKL 74
LL SPDN +R AE+ N P ++ + A ++ + + ++AVL R+L
Sbjct: 14 LLGNLLSPDNVVRKQAEETYEN---IPGQSKITFLLQAIRNTTAAE-EARQMAAVLLRRL 69
Query: 75 ALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXXX 134
A + + T I E L I+ + ++R K+ D AE A
Sbjct: 70 LSSAFDEVYPALPSDVQTAIKSELLMIIQ--------METQXSMRKKVCDIAAELARNLI 121
Query: 135 XXXXXXX-----QTLFEAIKNTDPNFRESSFRIFSSMPHLINSIDINHALPIFESGFTDP 189
+ LF+++ + + RE++ IF + P + + H L + +
Sbjct: 122 DEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQ-QHYLDVIKRMLVQC 180
Query: 190 SDE--------VKIAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAA 241
+ + A AF+ L + +DS + +
Sbjct: 181 MQDQEHPSIRTLSARATAAFI-----LANEHNVALFKHFADLLPGFLQAVNDSCYQNDDS 235
Query: 242 VFESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMCK 301
V +SL+E+ + PK + + +Q + + + R ALE++ SE A M +
Sbjct: 236 VLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSXNNMQRQLALEVIVTXSETAAAMLR 295
Query: 302 NNQNYAQSVVLDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKLN 361
+ N + L MM ++ D+D W ALDR+A L
Sbjct: 296 KHTNIVAQTIPQMLAMMVDLEEDED----WANADELEDDDFDSNAVAGESALDRMACGLG 351
Query: 362 GKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDP 421
GK + + + + QM+ + +W+ R A LMALS+ EGC + +++I+ V+ + DP
Sbjct: 352 GKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDP 411
Query: 422 HPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFSE 481
HPRV+Y CN +GQ++TDFAP Q HEK++ AL+ + RVQ HAAAAL+NF+E
Sbjct: 412 HPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTE 471
Query: 482 QATQSIMEPY---------XXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKY 532
+S++ PY KL V EQ +T+IA +A+ AE+KF+ Y
Sbjct: 472 DCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKL-VLEQVVTSIASVADTAEEKFVPY 530
Query: 533 YDTLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNE 592
YD MP L +++ E R+L+GK +EC +LI LAVGKEKF + +++QL + Q +
Sbjct: 531 YDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTD 590
Query: 593 --GIQDDDPLKTYLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSLIEEEEAAN 650
++DDDP +Y+ +W+R+C+IL ++F +TA +V+L++ ++ N
Sbjct: 591 FNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMEN 650
Query: 651 YQQYTDWDVVQI-QGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVP 709
W+ V + + I T+ L++K TA ++L YA LK F Y ++++ ++ VP
Sbjct: 651 MSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVV-KLMVP 709
Query: 710 SIDFYLHDGVRARGATLIPALFTSLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVT 769
+ FY HDGVR A +P L L A + + + Q+W + LI I +EP +V
Sbjct: 710 LLKFYFHDGVRVAAAESMPLL---LECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVL 766
Query: 770 KSYHYALVDCLGIVGNNGLNQEQLSQFTQGVNNNLTDVYE----RTKSRXXXXXXXXXXX 825
++ C+ ++G+ LN E + + L + ++ R R
Sbjct: 767 SEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEG 826
Query: 826 XXXXXXXXXXXXXXXINKSLAAVFKSAGVSYLQQFQTLWPIIHSYLQETEVF-ILLFALI 884
++ L ++F S L F+ L P+I + + + + L
Sbjct: 827 TLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLC 886
Query: 885 AIADMIEYTGDNSAPFKQHFVQKIKECLTFPEPSIRQGTAYLLGVCAQYAPNTYSDICLG 944
D+IE+ S + ++F++ + + + P +RQ AY LGV AQY + Y C
Sbjct: 887 IFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTE 946
Query: 945 SLETLFQIVNMPESRSEDNVNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHD 1004
+L L +++ +S++++NVN++EN A+ KI+ + N E+ +WL P+ D
Sbjct: 947 ALPLLVRVIQSADSKTKENVNATENCISAVGKIM-KFKPDCVNVEEVLPHWLSWLPLHED 1005
Query: 1005 EECAAFNYRMLAQLIDHNSPVIQG----NTAEIVDYVIQALHQKSIGGKNATAVVESAKK 1060
+E A + L LI+ N P++ G N +I + + ++I ++ AK+
Sbjct: 1006 KEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHED-----PCAKR 1060
Query: 1061 LLSTIPQEQAS 1071
L + + Q Q S
Sbjct: 1061 LANVVRQVQTS 1071
>At5g19820 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1116
Score = 360 bits (923), Expect = 9e-99
Identities = 270/1101 (24%), Positives = 485/1101 (43%), Gaps = 57/1101 (5%)
Query: 15 LLQGFASPDNAIRSAAEDALN-NNWITPEHIEVLLMFLAEQSAYSDDLTTAGLSAVLFRK 73
L+ S N RS+AE N P+ + + L L + S + + ++AVL RK
Sbjct: 27 LISHLMSSSNEQRSSAESLFNLAKQSNPDTLSLKLAHLLQLSPHPEG---RAMAAVLLRK 83
Query: 74 LALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXX 133
L R A +S ++ ++L + +I K+ D ++E A
Sbjct: 84 LLTRDD--------AYLWPRLSLSTQSSLKSSMLYCIQHEEAKSISKKICDTVSELASGI 135
Query: 134 XXXXX--XXXQTLFEAIKNTDPNFRESSFRIFSSMPHLINS-----IDINHALPIFESGF 186
+F+ + + P +ES+F I + + + I H + +
Sbjct: 136 LPENGWPELLPFVFQCVTSVTPKLQESAFLILAQLSQYVGETLTPHIKELHGVFLQCLSS 195
Query: 187 TDPSDEVKIAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAA-VFES 245
S +VKIAA+ A + + + L + ++ +EA A E
Sbjct: 196 NSASSDVKIAALNAVISFVQCLANSTERDRFQDVLPAMIRTLTESLNNGNEATAQEALEL 255
Query: 246 LIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSEC---APQMCKN 302
LIEL P+ + I+ + + LE S R A+E L +E AP M +
Sbjct: 256 LIELAGTEPRFLRRQLVDIVGSMLQIAEADSLEESTRHLAIEFLVTLAEARERAPGMVRK 315
Query: 303 NQNYAQSVVLDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKLNG 362
+ + + M+ + I+DD A + Y M ++ LDR+A+ L G
Sbjct: 316 LPQFIDRLFAVLMKMLED--IEDDPAW-YSAETEDEDAGETSNYSMGQECLDRLAISLGG 372
Query: 363 KYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDPH 422
+ +Q + +SEW++ A+L+AL+ AEGC V++ +D+++ MV+ PH
Sbjct: 373 NTIVPVAYQQFSAYLAASEWQKHHASLIALAQIAEGCSKVMIKNLDQVVSMVLSQFQSPH 432
Query: 423 PRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFSEQ 482
PRV++ N +GQ+STD P +Q+ HE++LPAL + + RVQ HAA+A++NFSE
Sbjct: 433 PRVRWAAINAIGQLSTDLGPDLQNQHHERVLPALAAAMDDFQNPRVQAHAASAVLNFSEN 492
Query: 483 ATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKYYDTLMPLLIN 542
T I+ PY K VQE ALT +A +A+++++ F KYYDT+MP L
Sbjct: 493 CTPEILSPYLDGVVSKLLVLLQNGKQMVQEGALTALASVADSSQEHFQKYYDTVMPYLKT 552
Query: 543 VLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNEGIQDDDPLKT 602
+L T R+L+ K MEC +L+ +AVGK++F +++++++ ++ Q ++ DDP+ +
Sbjct: 553 ILMNATDKSKRMLRAKSMECISLVGMAVGKDRFKEDARQVMEVLMSLQGSQMEADDPITS 612
Query: 603 YLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSL--IEEEEAANYQQYTDWDVV 660
Y+ Q+W+R+C+ L +DF ++A+ DV++ + E+ A + +
Sbjct: 613 YMLQAWARLCKCLGQDFLPYMKVVMPPLLQSAQLKPDVTITSADSEDEAEDSDDESMETI 672
Query: 661 QIQGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVPSIDFYLHDGVR 720
+ K I I TSVL++K TA +L YA LK F ++ ++ VP + FY H+ VR
Sbjct: 673 ILGDKRIGIKTSVLEEKATACNMLCCYADELKEGFFPWIDQV-APTLVPLLKFYFHEEVR 731
Query: 721 ARGATLIPALFTSLVSAV------GQDNDIVLQLWQIASNKLISGIISEPMPEVTKSYHY 774
+ +P L S A+ G+D + QL ++ + EP E+ S
Sbjct: 732 RAAVSAMPELMRSAKLAIEKGESQGRDLSYLKQLSDYIIPAMLEALHKEPDTEICVSMLE 791
Query: 775 ALVDCLGIVGNNGLNQEQLSQFTQGVNNNLTDVYERTKSRXXXXXXXXXXXXXXXXXXXX 834
A+ +CL I GN L++ ++ + +T R + R
Sbjct: 792 AINECLQISGNL-LDEGKIRSIVDEIKQVMTASSSRKRERGERAHAEDFDAEEGELIKEE 850
Query: 835 XXXXXXINKSLAAVFKSAGVSYLQQFQTLWPIIHSYL----------QETEVFILLFALI 884
I + + + ++ F + + SYL +E + I +F
Sbjct: 851 NEQEEEIFDQVGEILGTLVKTFKASFLPFFDELSSYLTPMWGRDKTAEERRIAICIF--- 907
Query: 885 AIADMIEYTGDNSAPFKQHFVQKIKECLTFPEPSIRQGTAYLLGVCAQYAPNTYSDICLG 944
D+ E + + + ++ + E P +RQ Y LGVCA++ + + +
Sbjct: 908 --DDVAEQCREAAFKYYDTYLPFVLEACNDESPEVRQAAVYGLGVCAEFGGSVFKPLIGE 965
Query: 945 SLETLFQIVNMPESRSEDNVNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHD 1004
+L L ++ +P +R +N + +NA A+ KI + SI + Q WL P+ +D
Sbjct: 966 ALSRLNVVIQLPNARQSENAMAYDNAVSAVGKICQFHRDSIDS-SQVLPAWLNCLPISND 1024
Query: 1005 EECAAFNYRMLAQLIDHNSPVIQG----NTAEIVDYVIQALHQKS-IGGKNATAVVESAK 1059
A + L +++ + G + +I+ + L K + + A ++ +
Sbjct: 1025 VLEAKVVHDQLCSMVERQDVDLLGPNNQHLPKILIVFAEVLTGKDVVTQETAGRMINILR 1084
Query: 1060 KLLSTIPQEQASALLQRYPPE 1080
+L T+P ++ PE
Sbjct: 1085 QLQQTLPPSALASTWSTLKPE 1105
>CE26971 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1092
Score = 298 bits (764), Expect = 2e-80
Identities = 253/1033 (24%), Positives = 450/1033 (43%), Gaps = 58/1033 (5%)
Query: 94 ISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXXXXXXXXXX-----QTLFEAI 148
+++E ++I +L+ + + +I+ K++D I+E A + + +
Sbjct: 76 LNEENKQRILAKVLEMIVHETELSIKKKIADLISEIASNLIDDSGDMTWGGVLELMDHCL 135
Query: 149 KNTDPNFRESSFRIFSSMPHLINSIDINHALP----IFESGFTDPSDEVKIAAVTAFVGY 204
K+ D + I P + + + H LP + E P ++K AV A + +
Sbjct: 136 KSEDLTGNYIALLILRGCPIIFGN-RLAHFLPTLKVVLEKCMATPDLQIKATAVRAVIAF 194
Query: 205 FKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAAVFESLIELVELAPKLFKDMFDQI 264
+ +D++ + E EL PK Q+
Sbjct: 195 AVDNDEEKDVVRLMTSLVPNVLQVCNETSDEDDSDGPLGE-FAELASSLPKCLNTHMSQV 253
Query: 265 IQFADMVIKNKDLEPSARTTALELLTVFSECAPQMCKNNQNYAQSVVLDTLVM-MTEVSI 323
+Q + NK+ R A+E++ + E AP+ K A +L+TL+ MTE+
Sbjct: 254 LQVTLAIAGNKEKNEMVRQNAIEVICSYMESAPKGLKKYAPGALGPILETLLSCMTEM-- 311
Query: 324 DDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKLNGKYLAAPLFQFLQQMITSSEWR 383
DDD EW +A A+DRVA +NGK + +++++TS +W+
Sbjct: 312 DDDVLNEWLNEIEEEEDYEDIPI-IAESAIDRVACCINGKVMLPVFLPLVEKLLTSEDWK 370
Query: 384 ERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDPHPRVQYGCCNVLGQISTDFAPL 443
+ AAL A S+ EGC+ + I++I+ + ++D HPRVQY CN +GQ+S+DFAP
Sbjct: 371 MKHAALRAFSAVGEGCQRSMEPHIEQIMAHITNYVNDAHPRVQYAACNAIGQMSSDFAPT 430
Query: 444 IQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFSEQATQSIMEPY------XXXXXX 497
+Q H ++PAL+ L + V RV HAA+ALVNF+E+ +SI+ Y
Sbjct: 431 LQKKCHAAVIPALLESLDRTDVPRVCAHAASALVNFAEECPKSIIGQYLPFILQKLENVL 490
Query: 498 XXXXXXXXXKLY--VQEQALTTIAFIAEAAEKKFIKYYDTLMPLLINVLRTDTGTESRVL 555
K Y V E +T IA +AEAAE+ F +++ L+P L+++L+ + G E + L
Sbjct: 491 SAVFNRLGDKRYQVVVENIVTAIASVAEAAEELFKEHHARLIPNLVHILQ-NVG-ELKEL 548
Query: 556 KGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNEGIQD---DDPLKTYLEQSWSRVC 612
+GK +EC +LI AVGKE+F + + E++ L +G++D DDP +Y+ SW+R C
Sbjct: 549 RGKTIECISLIGYAVGKEQFHATAIEILNLL----GDGMKDLAIDDPQYSYMISSWTRFC 604
Query: 613 RILREDFXXXXXXXXXXXXETAKATQDVSLIEEEEAANYQQYTDWDVVQIQGKHIAIHTS 672
IL DF A+ D ++ E+ ++ ++ + + K + I TS
Sbjct: 605 SILGADFAPFLPVVMDPVLRAARYRPDFNIFNNEDVHENEEGVEYHGIGGE-KTVGIRTS 663
Query: 673 VLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVPSIDFYLHDGVRARGATLIPALFT 732
L++K TA ++L +A +K F YV ++ E+A+ ++DF LHDGVR A ++P L T
Sbjct: 664 GLEEKATACDMLVAFAKEMKEAFMPYVVDVY-ELAIKNLDFGLHDGVRTASAEIMPCLLT 722
Query: 733 SLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVTKSYHYALVDCLGIVGNNGLNQEQ 792
+ D +LW L + + E E+ S+ + C+ ++ G+ +E+
Sbjct: 723 CVEKQGLADK---RRLWCEFLKALTTSMEEEDDVEILASFMTTIGSCIEVMKTEGIAEEE 779
Query: 793 LSQFTQGVNNNLTDVYERTKSR------XXXXXXXXXXXXXXXXXXXXXXXXXXINKSLA 846
+ + L + +R R + SL
Sbjct: 780 VQLIISVLLKQLENYGKRMSDRPVEDEDDDDAEAKEELDYFMELEASCLGAISDLTHSLM 839
Query: 847 AVFKSAGVSYLQQFQTLWPIIHSYLQETEVFILLFALIAIADMIEYTGDNSAPFKQHFVQ 906
FK G + I + F + + + D IE+ + +
Sbjct: 840 KEFK--GTIFEGMINVFNCAIQLIEGSKQYFERQWGMCLLDDAIEFGVGHMPTRFPKLIP 897
Query: 907 KIKECLTFPEPSIRQGTAYLLGVCA--QYAPNTYSDICLGSLETLFQIVNMPESR-SEDN 963
+ + L P +RQ +Y GV A + + Y + L LE L ++ ++R +E++
Sbjct: 898 IMYKLLGDEYPEVRQAASYGFGVMAINYHQISDYRNEILSCLEPLAAMIQREDARATEES 957
Query: 964 VNSSENASCAIAKILSSYGSSIPNFEQYTANWLKTFPVIHDEECAAFNYRMLAQLIDHNS 1023
++ENA A AKI+ + + + +L P D E + + Y LA+L D
Sbjct: 958 TVATENAISAFAKIIGNVPLPAEAYGKVVEMFLSWLPTYSDTEESPYIYTCLAELFDKQD 1017
Query: 1024 PVIQGNTAE---------IVDYVIQALHQKSIGGKNATAVVESAKKLLSTIPQ-EQASAL 1073
+ G + ++ A + G + +V K++ ++ PQ Q +
Sbjct: 1018 AALFGPENQNLPRIFLVCLLSIANDAFNDDDSGNQTKQRIVTILKQIYASFPQFAQQDGI 1077
Query: 1074 LQRYPPEIMQTIH 1086
+ + QT++
Sbjct: 1078 DEHLTSVLQQTLN 1090
>Hs16161756 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 414
Score = 114 bits (286), Expect = 6e-25
Identities = 97/396 (24%), Positives = 172/396 (42%), Gaps = 15/396 (3%)
Query: 683 LLQVYATVLKSFFASYVKEILTEVAVPSIDFYLHDGVRARGATLIPALFTSLVSAVGQDN 742
+L YA L+ F Y ++++ ++ VP + FY HD VR A +P L L A +
Sbjct: 1 MLVYYAKELREGFVEYTEQVV-KLMVPLLKFYFHDNVRVAAAESMPFL---LECARIRGP 56
Query: 743 DIVLQLWQIASNKLISGIISEPMPEVTKSYHYALVDCLGIVGNNGLNQEQLSQFTQGVNN 802
+ + Q+WQ + LI I +EP +V + + ++G+ LN E L + +
Sbjct: 57 EYLAQMWQFICDPLIKAIGTEPDTDVLSEIMNSFAKSIEVMGDGCLNDEHLEELGGILKA 116
Query: 803 NLTDVYE----RTKSRXXXXXXXXXXXXXXXXXXXXXXXXXXINKSLAAVFKSAGVSYLQ 858
L ++ R R ++ L ++F + L
Sbjct: 117 KLEGHFKNQELRQVKRQEENYDQQVEMSLQDEDECDVYILTKVSDILHSLFSTYKEKILP 176
Query: 859 QFQTLWPIIHSYLQETEVF-ILLFALIAIADMIEYTGDNSAPFKQHFVQKIKECLTFPEP 917
F+ L P+I + + + + + L D+IE+ S + ++F + + P
Sbjct: 177 WFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPTSFKYVEYFRWPMLLNMRDNNP 236
Query: 918 SIRQGTAYLLGVCAQYAPNTYSDICLGSLETLFQIVNMPESRSEDNVNSSENASCAIAKI 977
+RQ AY LGV AQ+ + Y +C ++ L +++ S+++ NV ++EN AI KI
Sbjct: 237 EVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCANSKTKKNVIATENCISAIGKI 296
Query: 978 LSSYGSSIPNFEQYTANWLKTFPVIHDEECAAFNYRMLAQLIDHNSPVIQGNTAEIVDYV 1037
L + + N ++ +WL P+ D+E A L LI+ N PV+ G + +
Sbjct: 297 L-KFKPNCVNVDEVLPHWLSWLPLHEDKEEAIQTLSFLCDLIESNHPVVIGPNNSNLPKI 355
Query: 1038 IQALHQKSIGGKNATAVVES--AKKLLSTIPQEQAS 1071
I + + I N T E AK+L + + Q Q S
Sbjct: 356 ISIIAEGKI---NETINYEDPCAKRLANVVRQVQTS 388
>At4g27640 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 651
Score = 99.4 bits (246), Expect = 3e-20
Identities = 150/707 (21%), Positives = 285/707 (40%), Gaps = 83/707 (11%)
Query: 11 TLVKLLQGFASPDNAIRSAAEDALNNNWITPEHIEVLLMFLAEQSAYSDDLTTAGLSAVL 70
+L LL F PDN R AED + P+ + L+ L ++A + ++ L+AVL
Sbjct: 4 SLELLLIQFLMPDNDARRQAEDQIKRLAKDPQVVPALVQHL--RTAKTPNVRQ--LAAVL 59
Query: 71 FRKLALRAPPSSKTIIIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECA 130
RK I + +S + + ++ +L++ + +R ++ ++ A
Sbjct: 60 LRKR------------ITGHWAKLSPQLKQHVKQSLIESITVENSPPVRRASANVVSVVA 107
Query: 131 XXXXXXXX--XXXQTLFEAIKNTDPNFRESSFRIFSSMPHLINSI------DINHALPIF 182
LF+ ++ + RE + +FSS+ I + D+ L
Sbjct: 108 KYAVPAGEWPDLLTFLFQCSQSAQEDHREVALILFSSLTETIGNTFRPYFADLQALL--L 165
Query: 183 ESGFTDPSDEVKIAAVTAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAAV 242
+ + S V++AA+ A + + + S +E +A +
Sbjct: 166 KCMQDESSSRVRVAALKAVGSFLEFTNDGDEVVKFRDFIPSILDVSRKCIASGEEDVAIL 225
Query: 243 -FESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMCK 301
FE EL+E L D I+QF+ V N++LE S R A+++++ ++ K
Sbjct: 226 AFEIFDELIESPAPLLGDSVKAIVQFSLEVSCNQNLESSTRHQAIQIVSWLAKYKYNSLK 285
Query: 302 NNQNYAQ--SVVLDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALK 359
++ V+ L ++ DDD A + + + +D +A+
Sbjct: 286 KHKLVIPILQVMCPLLAESSDQEDDDDLAPD----------------RASAEVIDTLAMN 329
Query: 360 LNGKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLID 419
L K++ P+ +F S+ + R A++ AL +EGC D++ ++D +L +V+ +
Sbjct: 330 LP-KHVFLPVLEFASVHCQSTNLKFREASVTALGVISEGCFDLMKEKLDTVLNIVLGALR 388
Query: 420 DPHPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNF 479
DP V+ +GQ + P I S ++ +LP L+ + +S + V+ + AL F
Sbjct: 389 DPELVVRGAASFAIGQFAEHLQPEILS-HYQSVLPCLLIAIEDTS-EEVKEKSHYALAAF 446
Query: 480 SEQATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKYYDTLMPL 539
E + I+ P +QE ++ I +A AAE+ F Y + ++ L
Sbjct: 447 CENMGEEIV-PLLDHLMGKLMAALENSPRNLQETCMSAIGSVAAAAEQAFNPYAERVLEL 505
Query: 540 L--INVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQLFITYQNEGIQDD 597
+ VL D +R K + L + K YQ ++
Sbjct: 506 MKFFMVLTKDEDLRARARKKE---------LTITK----------------YQGFELEFS 540
Query: 598 DPLKTYLEQSWSRVCRILREDFXXXXXXXXXXXXETAKATQDVSL-IEEEEAANYQQY-- 654
+ L+ Y +S V IL + F + ++ I+E + N +
Sbjct: 541 E-LREYTHGFFSNVAEILDDTFAQYLPRVMPLVFASCNLDDGSAVDIDESDDENVNDFGG 599
Query: 655 --TDWDV-VQIQGKHIAIHTSVLDDKVTAMELLQVYATVLKSFFASY 698
+D D + + ++I++ T VLD+K A + L ++A KS FA Y
Sbjct: 600 VSSDDDADDEPRVRNISVRTGVLDEKAAATQALGLFALHTKSAFAPY 646
>SPBC14F5.03c [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1067
Score = 71.2 bits (173), Expect = 8e-12
Identities = 126/650 (19%), Positives = 245/650 (37%), Gaps = 51/650 (7%)
Query: 94 ISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXXXXXXXXXXQTLF--EAIKNT 151
+ + QIR LL + + + +RH IA A + F +A +
Sbjct: 76 VDADVQNQIRSNLLDITLKEPESIVRHAFGRVIAALAKLDLPEGKWNELSAFLVQATMDQ 135
Query: 152 DPNFRESSFRIFSSMPHLINSIDINHAL-----PIFESGFTDPSDEVKIAAVTAFVGYFK 206
+ + RE + + S + ++D+++ L +F TD S V++ +V +
Sbjct: 136 NDSIREMAVYVLYS---IAETVDLDNKLLLDFVNLFSQTITDSSRTVRVTSVQGLGAIAE 192
Query: 207 QLPKNNWAXXXXXXXXXXXXXXXXXDDSKD---EALAAVFESLIELVELAPKLFKDMFDQ 263
L ++ D + +A VF+ + + +
Sbjct: 193 VLESDDKKLLHAYRATLPGMLLVLQDVVQVGDVDASKQVFDVFNTFLIASGAIISKALGN 252
Query: 264 IIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMCKNNQ--NYAQSVVLDTLVMMTEV 321
II+ + +K ++ R AL + C + Q + +VL + + TE
Sbjct: 253 IIEIITGIANSKQVDDEIRCMALSFII---SCIRFKSRKLQALKLGKPLVLTLMEVATEE 309
Query: 322 SIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKLNGKYLAAPLFQFLQQMITSSE 381
+ DD +A +++D ++ L+ + P+F+ S +
Sbjct: 310 TTDD--------------IDEDCPARLALRSIDLLSTHLSPSQVFYPMFEAACAFSQSPQ 355
Query: 382 WRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDPHPRVQYGCCNVLGQISTDFA 441
R AAL+++ A EG + + + I +++ + D V+ L QI+ +
Sbjct: 356 ASYRKAALLSIGVAVEGSSESVAGNLPNIFPIIINGLCDNDMDVRQAALLALSQIAVEI- 414
Query: 442 PLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFSEQATQSIMEPYXXXXXXXXXX 501
P S H ++LP L+ +L S+ +V A + E +S + Y
Sbjct: 415 PTEVSKHHAQLLP-LVFELMSTQGVKVGKSACNCIDALLEGLDKSEISGYLPMLMERLVG 473
Query: 502 XXXXXKLY-VQEQALTTIAFIAEAAEKKFIKYYDTLMPLLINVLRTDTGTESRVLKGKCM 560
++ I A AA+ FI Y++ M L L T E L+G M
Sbjct: 474 LLEFSDTPDIKSCVAAAIGSAAFAAQDDFIPYFERTMASLSQCLHTTDDDEGYELRGTVM 533
Query: 561 ECSTLIALAVGKEKFASYSQELIQLFITYQNEGIQ-DDDPLKTYLEQSWSRVCRILREDF 619
+ IA AVGK+ F Y+++LIQL EGIQ D L+ ++ + R+ +E+F
Sbjct: 534 DTLGAIANAVGKQAFLPYTEQLIQL----AYEGIQIDHSRLRECSFCFYAVLARVYKEEF 589
Query: 620 XXXXXXXXXXXXETAKATQDVSLIEEEEAANYQQYTD-WDVVQIQ--------GKHIAIH 670
++ + L E A ++ + D V+ K + ++
Sbjct: 590 APFLEHIVPALFKSIDQDESDILSERIGAPTAEEISQLLDSVETNEEENDEELEKAMGVN 649
Query: 671 TSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVPSIDFYLHDGVR 720
+++ +K A + L + + F Y++ + ++ + FY +GVR
Sbjct: 650 SAIAMEKEIAADALGEICMYVGAPFTPYLEPTVEKLVACTTHFY--EGVR 697
>YER110c [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1113
Score = 70.9 bits (172), Expect = 1e-11
Identities = 99/521 (19%), Positives = 196/521 (37%), Gaps = 33/521 (6%)
Query: 86 IIAKNITHISKEALKQIRDTLLKGFISQRPNNIRHKLSDAIAECAXXXXXXXX--XXXQT 143
+++K+ I + I+ +LL+ S+ N+RH + IA
Sbjct: 66 LVSKHWNAIDESTRASIKTSLLQTAFSEPKENVRHSNARVIASIGTEELDGNKWPDLVPN 125
Query: 144 LFEAIKNTDPNFRESS-FRIFSSMPHLINSID--INHALPIFESGFTDPSD-EVKIAAVT 199
L + D R+++ F +FS + +S+ I+ L +F DPS E++ +
Sbjct: 126 LIQTASGEDVQTRQTAIFILFSLLEDFTSSLSGHIDDFLALFSQTINDPSSLEIRSLSAQ 185
Query: 200 AFVGYFKQLPKNNWAXXXXXXXXXXXX--------XXXXXDDSKDEALAAVFESLIELVE 251
A + + DD+ + L +F L + +
Sbjct: 186 ALNHVSALIEEQETINPVQAQKFAASIPSVVNVLDAVIKADDTMNAKL--IFNCLNDFLL 243
Query: 252 LAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSECAPQMCKNNQNYAQSVV 311
L +L + +I+ + + N +++ R AL+ + ++ + V
Sbjct: 244 LDSQLTGNFIVDLIKLSLQIAVNSEIDEDVRVFALQFIISSLSYRKSKVSQSKLGPEITV 303
Query: 312 LDTLVMMTEVSIDDDQAIEWQXXXXXXXXXXXXTYDMARQALDRVALKLNGKYLAAPLFQ 371
V E+ +DD+ E + A + L + +L +A+ + +
Sbjct: 304 AALKVACEEIDVDDELNNEDETGENEENTPSSS----AIRLLAFASSELPPSQVASVIVE 359
Query: 372 FLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDPHPRVQYGCCN 431
+ M+ S+ ER A L+A+S A G D ++ + DKI+ + + D P V+
Sbjct: 360 HIPAMLQSANVFERRAILLAISVAVTGSPDYILSQFDKIIPATINGLKDTEPIVKLAALK 419
Query: 432 VLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQTHAAAALVNFSE----QATQSI 487
+ Q++TD + + HE+ LP +I + S+ + +A AL E A
Sbjct: 420 CIHQLTTDLQDEV-AKFHEEYLPLIIDIIDSAKNIVIYNYATVALDGLLEFIAYDAIAKY 478
Query: 488 MEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKYYDTLMPLLINVLRTD 547
++P A+ + AF A +A FI Y+ T + L ++
Sbjct: 479 LDPLMNKLFYMLESNESSKLRCAVVSAIGSAAFAAGSA---FIPYFKTSVHYLEKFIQNC 535
Query: 548 TGTESR-----VLKGKCMECSTLIALAVGKEKFASYSQELI 583
+ E L+ E + +A AV + FA +++ L+
Sbjct: 536 SQIEGMSEDDIELRANTFENISTMARAVRSDAFAEFAEPLV 576
>Hs14756038 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 160
Score = 62.8 bits (151), Expect = 3e-09
Identities = 41/131 (31%), Positives = 66/131 (50%), Gaps = 4/131 (3%)
Query: 665 KHIAIHTSVLDDKVTAMELLQVYATVLKSFFASYVKEILTEVAVPSIDFYLHDGVRARGA 724
+ I TS L+ KVTA ++L YA L+ F +Y ++++ ++ VP + FY D VR A
Sbjct: 16 QRFGIKTSGLEAKVTACQMLVYYAKELREGFVNYTEQVV-KLMVPLLKFYFQDNVRVAAA 74
Query: 725 TLIPALFTSLVSAVGQDNDIVLQLWQIASNKLISGIISEPMPEVTKSYHYALVDCLGIVG 784
+P L L A + + Q+WQ N LI I +EP +V + ++G
Sbjct: 75 ESMPFL---LECARICGPEYLAQMWQFIRNPLIKAIGTEPDTDVLSEIMNSFAKFTEVMG 131
Query: 785 NNGLNQEQLSQ 795
++ LN E L +
Sbjct: 132 DDCLNDEYLEE 142
>Hs18874099 [YU] KOG2171 Karyopherin (importin) beta 3
Length = 1081
Score = 58.5 bits (140), Expect = 5e-08
Identities = 85/360 (23%), Positives = 144/360 (39%), Gaps = 17/360 (4%)
Query: 236 DEALAA-VFESLIELVELAPKLFKDMFDQIIQFADMVIKNKDLEPSARTTALELLTVFSE 294
DEA A E+L EL+E + +++ F V +N L + R L LT +
Sbjct: 217 DEAKACEALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLTFLVK 276
Query: 295 CAPQMCKNNQNYAQSVVLDTLVMMTEVSID----DDQAIEWQXXXXXXXXXXXXTYDMAR 350
+ N+ +L TL + D + + + A
Sbjct: 277 VKSKALLKNRLLPP--LLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHFAV 334
Query: 351 QALDRVALKLNGKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLMIEI-DK 409
Q +D +AL L + L L L++ + S +R A L+ L+ ++G D + +
Sbjct: 335 QVVDMLALHLPPEKLCPQLMPMLEEALRSESPYQRKAGLLVLAVLSDGAGDHIRQRLLPP 394
Query: 410 ILEMVVPLIDDPHPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSSVDRVQ 469
+L++V ++DP V+ LGQ S + P I S S E ++P L++ L SV
Sbjct: 395 LLQIVCKGLEDPSQVVRNAALFALGQFSENLQPHISSYSRE-VMPLLLAYL--KSVPLGH 451
Query: 470 TH----AAAALVNFSEQATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAA 525
TH A AL NF E + +E A++ + IA AA
Sbjct: 452 THHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAA 511
Query: 526 EKKFIKYYDTLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQL 585
+ + Y+ +M L L T + + ++ + +E ++A AVG E ++E QL
Sbjct: 512 QVSLLPYFPAIMEHLREFLLTGR-EDLQPVQIQSLETLGVLARAVG-EPMRPLAEECCQL 569
>At2g16950 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 827
Score = 56.2 bits (134), Expect = 3e-07
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 23/238 (9%)
Query: 362 GKYLAAPLFQFLQQMITSS---EWRERFAALMALSSAAEGCRDVL---MIEIDKILEMVV 415
G + L +Q+ +++S W++R AA++AL + AEGC + L + E I+ ++
Sbjct: 384 GDEILPALMPLIQKNLSASGDEAWKQREAAVLALGAIAEGCMNGLYPHLSEASLIVAFLL 443
Query: 416 PLIDDPHPRVQYGCCNVLGQISTDFAPLIQSTSH-------EKILPALISKLTSSSVDRV 468
PL+DD P ++ C L + LIQ + + EK+L L+ +L ++ RV
Sbjct: 444 PLLDDKFPLIRSISCWTLSRFG---KYLIQESGNPKGYEQFEKVLMGLLRRLLDTN-KRV 499
Query: 469 QTHAAAALVNFSEQATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKK 528
Q A +A E A + ++ P+ + I +A++ ++
Sbjct: 500 QEAACSAFATVEEDAAEELV-PHLGVILQHLMCAFGKYQRRNLRIVYDAIGTLADSVREE 558
Query: 529 FIK--YYDTLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFASYSQELIQ 584
K Y + LMP L+ + + ++ + +EC T I+ A+G FA ++Q + Q
Sbjct: 559 LNKPAYLEILMPPLVAKWQQLSNSDKDLF--PLLECFTSISQALG-VGFAPFAQPVFQ 613
>7295355 [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 884
Score = 56.2 bits (134), Expect = 3e-07
Identities = 101/501 (20%), Positives = 184/501 (36%), Gaps = 68/501 (13%)
Query: 143 TLFEAIKNTDPNFRESSF----RIFSSMPHLINSIDINHALPIFESGFTDPSDEVKIAAV 198
+L E + N D N E +F +I ++ ++ +N +P F F S +++ A+
Sbjct: 138 SLCEMLDNQDYNVCEGAFSALQKICEDSAGILENMPLNTMIPKFLEYFKHSSPKIRSHAI 197
Query: 199 TAFVGYFKQLPKNNWAXXXXXXXXXXXXXXXXXDDSKDEALAAVFESLIELVELAPKLFK 258
Q N D+ V +L+ LV + L
Sbjct: 198 ACI----NQFIINRSQALMLNIDSLIQNLLDVPSDNDPAVRMNVCHALVGLVGVRIDLMM 253
Query: 259 DMFDQIIQFADMVIKNKDLEPSARTTALE--------------LLTVFSECAPQMCKNNQ 304
QII+ ++++++D + + A E L + S+ P + Q
Sbjct: 254 PHMSQIIEL--ILLRSQDADENVALQATEFWLSLGKQRNCRDILSPILSQLVPVLVSRTQ 311
Query: 305 NYAQSVVLDTLVMMTEVSIDDDQAIEWQXXX-------------XXXXXXXXXTYDMARQ 351
Y ++ D +++ +V DD + Q +D A
Sbjct: 312 -YTET---DIILLKGDVGEDDKEPDRQQDISPRFHMSRVHGISNELDENSDDDMWDSALN 367
Query: 352 -------ALDRVALKLNGKYLAAPLFQFLQQMITSSEWRERFAALMALSSAAEGCRDVLM 404
ALD ++ K+ G + L++ + EW + + +MAL + AEGC L+
Sbjct: 368 LRKCSACALDIIS-KIFGDVCLPLMLPILKEALFHQEWVIKESGVMALGAIAEGCMQGLI 426
Query: 405 IEIDKILEMVVPLIDDPHPRVQYGCCNVLGQISTDFAPLIQSTSHEKILPALISKLTSSS 464
+ +++ ++ + D P V+ C + F + + H+K L LI +L
Sbjct: 427 PHLPELIPYLITCLSDKKPLVRSITCWTFMR----FPKWVLNQPHDKYLEPLIEELLKCI 482
Query: 465 VD---RVQTHAAAALVNFSEQATQSIMEPYXXXXXXXXXXXXXXXKLYVQEQAL---TTI 518
+D RVQ A +A V E+A ++ PY Y Q L +
Sbjct: 483 LDSNKRVQEAACSAFVALEEEACTQLV-PYLENMLKTFVLAFSK---YHQRNLLIMYDVV 538
Query: 519 AFIAEAAEKKFIK--YYDTLMPLLINVLRTDTGTESRVLKGKCMECSTLIALAVGKEKFA 576
+AE+ K Y D LMP L++ + ++ +EC + IA A+ + F
Sbjct: 539 GLLAESVGHHLNKPQYIDILMPPLMDKWNLVKDDDKDII--YLLECLSSIATAL-QSSFL 595
Query: 577 SYSQELIQLFITYQNEGIQDD 597
Y + + I+ E I D
Sbjct: 596 PYCDSVYRKGISIIEETINQD 616
>SPAC2F3.06c [YU] KOG2023 Nuclear transport receptor
Karyopherin-beta2/Transportin (importin beta
superfamily)
Length = 910
Score = 54.7 bits (130), Expect = 8e-07
Identities = 58/253 (22%), Positives = 105/253 (40%), Gaps = 25/253 (9%)
Query: 373 LQQMITSSEWRERFAALMALSSAAEGCRDVLMIEIDKILEMVVPLIDDPHPRVQYGCCNV 432
L+Q +TS +W+ + A ++A+ + AEGC D ++ + ++ + L+D P V+ C
Sbjct: 419 LKQSLTSEDWKVQEAGVLAVGAIAEGCMDGMVQYLPELYPYFLSLLDSKKPLVRTITCWT 478
Query: 433 LGQISTDFAPLIQSTSHEKILPALISKLTSSSVD---RVQTHAAAALVNFSEQATQSI-- 487
LG+ S + L +K L+ L VD +VQ +A EQA S+
Sbjct: 479 LGRYSKWASCLESEEDRQKYFVPLLQGLLRMVVDNNKKVQEAGCSAFAILEEQAGPSLVP 538
Query: 488 -MEPYXXXXXXXXXXXXXXXKLYVQEQALTTIAFIAEAAEKKFIKYYDTLMPLLINVLRT 546
+EP L + + T ++ A K +Y + L+ L+
Sbjct: 539 YLEPILTNLAFAFQKYQRKNVLILYDAVQTLADYVGSALNDK--RYIELLITPLLQKWSM 596
Query: 547 DTGTESRVLKGKCMECSTLIALAVGKEKFASYSQE-----------LIQLFITYQNE--- 592
+ + EC + +A+A+ ++ FA ++ E + L T QN+
Sbjct: 597 IPDDDPNLF--PLFECLSSVAVAL-RDGFAPFAAETYARTFRILRNTLYLITTAQNDPTV 653
Query: 593 GIQDDDPLKTYLE 605
+ D D L T L+
Sbjct: 654 DVPDRDFLVTTLD 666
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,274,347
Number of Sequences: 60738
Number of extensions: 2077081
Number of successful extensions: 5300
Number of sequences better than 1.0e-05: 16
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 5208
Number of HSP's gapped (non-prelim): 33
length of query: 1090
length of database: 30,389,216
effective HSP length: 117
effective length of query: 973
effective length of database: 23,282,870
effective search space: 22654232510
effective search space used: 22654232510
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)