ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3520 good L KOG3997 Replication, recombination and repair Major apurinic/apyrimidinic endonuclease/3'-repair diesterase APN1
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3520 1239373 1240476 368
(368 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL114c [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-... 473 e-133
CE28953 [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-... 244 1e-64
SPCC622.17 [L] KOG3997 Major apurinic/apyrimidinic endonuclease/... 236 4e-62
ECU11g1550i [L] KOG3997 Major apurinic/apyrimidinic endonuclease... 219 4e-57
>YKL114c [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-repair
diesterase APN1
Length = 367
Score = 473 bits (1218), Expect = e-133
Identities = 227/325 (69%), Positives = 265/325 (80%), Gaps = 3/325 (0%)
Query: 15 SFVRSTTSKFKFGAHVSGAGGISNSVTNAHEIGCNSFAMFLKSPRQWNSKPYPESEITKF 74
SFVRS SK+KFGAH+SGAGGISNSVTNA GCNSFAMFLKSPR+W S Y + EI KF
Sbjct: 6 SFVRSAVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKF 65
Query: 75 NENCAKLSYDPKTDILPHGSYFINLGNPDHEKAEKAYDAFLDDLVRCEQLGIGHYNFHPG 134
+NCA +Y+P TD+LPHG YFINL NPD EKAEK+Y++F+DDL RCEQLGIG YN HPG
Sbjct: 66 KKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPG 125
Query: 135 SSLDGDHDTQLKQLAGYINKAINDTKFVNIVLENMAGHGNLIGSNLEDLKTVIDMIEDKN 194
S+L GDH QLKQLA Y+NKAI +TKFV IVLENMAG GNL+GS+L DLK VI MIEDK+
Sbjct: 126 STLKGDHQLQLKQLASYLNKAIKETKFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKS 185
Query: 195 RVGVCVDTCHTYAAGYDISTKNAFDQFWKKFDAIIGFKYLKAIHLNDSKAPLAANADRHE 254
R+GVC+DTCHT+AAGYDIST F+ FWK+F+ +IGFKYL A+HLNDSKAPL AN D HE
Sbjct: 186 RIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHE 245
Query: 255 ILGQGFLGLEVFKIIAHSEFLQGIPIVLETPQKEDAGYGEEIKLLEWLETIDEE---ENK 311
LGQG+LG++VF++IAHSE+LQGIPIVLETP + D GYG EIKL+EWLE+ E E+K
Sbjct: 246 RLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEGYGNEIKLMEWLESKSESELLEDK 305
Query: 312 DYIEKRLALNKLGEKSRKEFQAKFD 336
+Y EK L KLG KSRKE KF+
Sbjct: 306 EYKEKNDTLQKLGAKSRKEQLDKFE 330
>CE28953 [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-repair
diesterase APN1
Length = 396
Score = 244 bits (623), Expect = 1e-64
Identities = 121/282 (42%), Positives = 181/282 (63%), Gaps = 5/282 (1%)
Query: 19 STTSKFKFGAHVSGAGGISNSVTNAHEIGCNSFAMFLKSPRQWNSKPYPESEITKFNENC 78
S S G HVS AGG+ ++ NA GC SFAMF+++ R WN KP E + + +
Sbjct: 113 SEGSSKMLGFHVSAAGGLEQAIYNARAEGCRSFAMFVRNQRTWNHKPMSEEVVENWWKAV 172
Query: 79 AKLSYDPKTDILPHGSYFINLGNPDHEKAEKAYDAFLDDLVRCEQLGIGHYNFHPGSSLD 138
+ ++ P I+PHGSY +N G+P+ EK EK+ A LD+ R E+LGI YNFHPGS++
Sbjct: 173 RETNF-PLDQIVPHGSYLMNAGSPEAEKLEKSRLAMLDECQRAEKLGITMYNFHPGSTVG 231
Query: 139 G-DHDTQLKQLAGYINKAINDTKFVNIVLENMAGHGNLIGSNLEDLKTVIDMIEDKNRVG 197
+ + + +A I+ + T+ + +VLE MAG GN IG E+LK +ID ++ K+RVG
Sbjct: 232 KCEKEECMTTIAETIDFVVEKTENIILVLETMAGQGNSIGGTFEELKFIIDKVKVKSRVG 291
Query: 198 VCVDTCHTYAAGYDISTKNAFDQFWKKFDAIIGFKYLKAIHLNDSKAPLAANADRHEILG 257
VC+DTCH +A GYDI T+ A+++ K F ++G+ YLKAIH+NDSK + + DRHE +G
Sbjct: 292 VCIDTCHIFAGGYDIRTQKAYEEVMKNFGEVVGWNYLKAIHINDSKGDVGSKLDRHEHIG 351
Query: 258 QGFLGLEVFKIIAHSEFLQGIPIVLETPQKEDAGYGEEIKLL 299
QG +G F+++ + L GIP++LETP+ + Y EE+ ++
Sbjct: 352 QGKIGKAAFELLMNDNRLDGIPMILETPEGK---YPEEMMIM 390
>SPCC622.17 [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-repair
diesterase APN1
Length = 366
Score = 236 bits (602), Expect = 4e-62
Identities = 126/315 (40%), Positives = 181/315 (57%), Gaps = 25/315 (7%)
Query: 46 IGCNSFAMFLKSPRQWNSKPYPESEITKFNENCAKLSYDPKTDILPHGSYFINLGNPDHE 105
I NS A F+KS R+W S E KF E +++ +D +L HGSY IN+ N D +
Sbjct: 15 ISANSCAFFVKSQRKWTSPDLSEDVAQKFLETASEMKFDASKQVLVHGSYLINMANADEQ 74
Query: 106 KAEKAYDAFLDDLVRCEQLGIGHYNFH------------------------PGSSLDGDH 141
K E+A++ F+DDL RCE+LG+G YNF PGS+
Sbjct: 75 KREQAFNCFVDDLKRCERLGVGLYNFQYVIHSVLYLLIFYPKRTNSFDLCSPGSTASCTK 134
Query: 142 DTQLKQLAGYINKAINDTKFVNIVLENMAGHGNLIGSNLEDLKTVIDMIEDKNRVGVCVD 201
+ + LA IN+A +TK V IV ENMAG GN +G +D + I++ +R VC+D
Sbjct: 135 EEGINNLAECINRAHEETKSVIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLD 194
Query: 202 TCHTYAAGYDISTKNAFDQFWKKFDAIIGFKYLKAIHLNDSKAPLAANADRHEILGQGFL 261
TCHT+AAGYDI T+ ++ + +FD +G KY+ HLNDSKAPL +N D HE +G GFL
Sbjct: 195 TCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFL 254
Query: 262 GLEVFKIIAHSEFLQGIPIVLETPQKEDAGYGEEIKLLEWLETIDEEENKDYIEKRLALN 321
GLE F++I + GIP+VLETP K + +E++LL ++ ++ + +++ L+
Sbjct: 255 GLEPFRLIMNDSRWDGIPLVLETPAKSPEQWKKEVELLRFM-VGKSSDDVELMKESARLS 313
Query: 322 KLGEKSRKEFQAKFD 336
LG SRKE KF+
Sbjct: 314 NLGAASRKEHLNKFE 328
>ECU11g1550i [L] KOG3997 Major apurinic/apyrimidinic endonuclease/3'-repair
diesterase APN1
Length = 275
Score = 219 bits (559), Expect = 4e-57
Identities = 109/276 (39%), Positives = 170/276 (61%), Gaps = 9/276 (3%)
Query: 27 GAHVSGAGGISNSVTNAHEIGCNSFAMFLKSPRQWNSKPYPESEITKFNENCAKLSYDPK 86
GAH+S + GI +G ++ A+FLKS R++ + P + F +
Sbjct: 6 GAHLSISKGIHTIQAQMELLGLDTCAIFLKSQRRYLTPPMKQGAAEMFRAHVRHPEL--- 62
Query: 87 TDILPHGSYFINLGNPDHEKAEKAYDAFLDDLVRCEQLGIGHYNFHPGSSLDGDHDTQLK 146
I+PHGSY IN GNPD +K+ + +DDL RC+ LGIG YN HPGSS L+
Sbjct: 63 --IVPHGSYLINFGNPD--LVDKSMECLVDDLERCKSLGIGMYNMHPGSSKGKGRAECLR 118
Query: 147 QLAGYINKAINDTKFVNIVLENMAGHGNLIGSNLEDLKTVIDMIEDKNRVGVCVDTCHTY 206
+ ++N A++ + V +++ENMAG G+++GS+ E+L+ +I IED+ R+GVC+DTCH +
Sbjct: 119 SIGHHVNTALSRVQGVTVLIENMAGQGSVVGSSFEELRDIIGGIEDRERIGVCLDTCHLF 178
Query: 207 AAGYDISTKNAFDQFWKKFDAIIGFKYLKAIHLNDSKAPLAANADRHEILGQGFLGLEVF 266
AG+DI+T+ F + ++FD ++G ++LKA+H+NDSK L + DRHE +G+G +G + F
Sbjct: 179 GAGFDITTEEKFLEVMERFDRVVGLEFLKAMHINDSKEALGSKKDRHESIGKGMIGEKAF 238
Query: 267 KIIAHSEFLQGIPIVLETPQKEDAGYGEEIKLLEWL 302
+ I +S+ IP++LETP + Y EE L L
Sbjct: 239 RFIMNSKVFDNIPLILETP--DPGKYKEEADFLRSL 272
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.317 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,322,554
Number of Sequences: 60738
Number of extensions: 1021044
Number of successful extensions: 2602
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2591
Number of HSP's gapped (non-prelim): 4
length of query: 368
length of database: 30,389,216
effective HSP length: 108
effective length of query: 260
effective length of database: 23,829,512
effective search space: 6195673120
effective search space used: 6195673120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)