ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3526 check: MH R KOG0586 General function prediction only Serine/threonine protein kinase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3526 1240990 1242612 541
(541 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YKL116c [R] KOG0586 Serine/threonine protein kinase 370 e-102
SPBC337.04 [R] KOG0586 Serine/threonine protein kinase 120 7e-27
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 110 5e-24
7302464 [R] KOG0586 Serine/threonine protein kinase 108 2e-23
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 107 6e-23
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 104 3e-22
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 104 3e-22
YDR507c [D] KOG0588 Serine/threonine protein kinase 104 4e-22
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 102 1e-21
At3g17510 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
At1g48260 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 102 2e-21
7290150 [T] KOG0583 Serine/threonine protein kinase 100 4e-21
7299438 [R] KOG0586 Serine/threonine protein kinase 100 7e-21
At1g29230 [T] KOG0583 Serine/threonine protein kinase 100 1e-20
YCL024w [T] KOG0583 Serine/threonine protein kinase 99 1e-20
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 99 1e-20
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 99 2e-20
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
CE28643 [T] KOG0583 Serine/threonine protein kinase 97 5e-20
CE07458 [T] KOG0583 Serine/threonine protein kinase 97 5e-20
CE27768 [R] KOG0586 Serine/threonine protein kinase 97 6e-20
CE23838 [R] KOG0586 Serine/threonine protein kinase 97 6e-20
At5g58380 [T] KOG0583 Serine/threonine protein kinase 97 6e-20
CE16081 [T] KOG0583 Serine/threonine protein kinase 97 8e-20
7299437 [R] KOG0586 Serine/threonine protein kinase 97 8e-20
At2g34180 [T] KOG0583 Serine/threonine protein kinase 96 1e-19
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 96 1e-19
7302570 [R] KOG0586 Serine/threonine protein kinase 96 2e-19
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 95 2e-19
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 2e-19
CE28479 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
CE28218 [D] KOG0588 Serine/threonine protein kinase 95 2e-19
At2g26980 [T] KOG0583 Serine/threonine protein kinase 95 2e-19
YKL101w [D] KOG0588 Serine/threonine protein kinase 95 3e-19
At4g24400 [T] KOG0583 Serine/threonine protein kinase 95 3e-19
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 94 4e-19
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 94 4e-19
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 94 4e-19
7294217 [D] KOG0588 Serine/threonine protein kinase 94 4e-19
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 94 5e-19
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 94 7e-19
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 92 2e-18
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 91 3e-18
At5g45810 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
At3g01090 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
At2g25090 [T] KOG0583 Serine/threonine protein kinase 91 3e-18
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 91 4e-18
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 91 4e-18
At5g01820 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
At2g38490 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
7300413 [T] KOG0583 Serine/threonine protein kinase 91 4e-18
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 91 6e-18
At5g57630 [T] KOG0583 Serine/threonine protein kinase 91 6e-18
At4g18700 [T] KOG0583 Serine/threonine protein kinase 91 6e-18
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 90 8e-18
At5g07070 [T] KOG0583 Serine/threonine protein kinase 90 8e-18
At1g30270 [T] KOG0583 Serine/threonine protein kinase 90 8e-18
YDR477w [T] KOG0583 Serine/threonine protein kinase 90 1e-17
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
At5g10930 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
At1g01140 [T] KOG0583 Serine/threonine protein kinase 90 1e-17
7303211 [T] KOG4717 Serine/threonine protein kinase 90 1e-17
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 89 1e-17
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 89 1e-17
At5g35410 [T] KOG0583 Serine/threonine protein kinase 89 1e-17
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 89 1e-17
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 89 2e-17
7290249 [R] KOG0586 Serine/threonine protein kinase 89 2e-17
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 88 3e-17
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 88 3e-17
Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 88 3e-17
At3g29160 [T] KOG0583 Serine/threonine protein kinase 88 3e-17
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 88 4e-17
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 88 4e-17
CE00847 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
At5g45820 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
At5g39440 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
7302860 [T] KOG0696 Serine/threonine protein kinase 88 4e-17
7297080 [T] KOG0583 Serine/threonine protein kinase 88 4e-17
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 87 5e-17
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 87 5e-17
7303111 [T] KOG0695 Serine/threonine protein kinase 87 5e-17
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 87 6e-17
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 87 6e-17
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 87 6e-17
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 87 8e-17
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 87 8e-17
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 86 1e-16
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 86 1e-16
At5g28290 [R] KOG0589 Serine/threonine protein kinase 86 1e-16
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 86 1e-16
SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase 86 1e-16
CE17354 [T] KOG0694 Serine/threonine protein kinase 86 1e-16
CE17353 [T] KOG0694 Serine/threonine protein kinase 86 1e-16
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 86 2e-16
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 85 2e-16
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 85 2e-16
CE18454 [T] KOG4717 Serine/threonine protein kinase 85 2e-16
YPL141c [T] KOG0583 Serine/threonine protein kinase 85 3e-16
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 85 3e-16
CE29092 [T] KOG0694 Serine/threonine protein kinase 85 3e-16
CE17284 [T] KOG0583 Serine/threonine protein kinase 85 3e-16
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 84 4e-16
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 4e-16
At5g25110 [T] KOG0583 Serine/threonine protein kinase 84 4e-16
At3g44200 [R] KOG0589 Serine/threonine protein kinase 84 4e-16
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 5e-16
At4g33950 [T] KOG0583 Serine/threonine protein kinase 84 5e-16
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 84 7e-16
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 84 7e-16
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 84 7e-16
Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 84 7e-16
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 83 1e-15
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 83 1e-15
CE02586 [T] KOG0696 Serine/threonine protein kinase 83 1e-15
At3g04810 [R] KOG0589 Serine/threonine protein kinase 83 1e-15
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 83 1e-15
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 82 2e-15
CE29298 [T] KOG0690 Serine/threonine protein kinase 82 2e-15
CE18646 [T] KOG0690 Serine/threonine protein kinase 82 2e-15
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 82 2e-15
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 82 2e-15
Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 82 2e-15
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 82 3e-15
At5g66880 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
At2g30360 [T] KOG0583 Serine/threonine protein kinase 82 3e-15
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 81 4e-15
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 81 4e-15
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 81 4e-15
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
CE21239 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
CE18366 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
At3g23000 [T] KOG0583 Serine/threonine protein kinase 81 4e-15
At2g45490 [D] KOG0580 Serine/threonine protein kinase 81 4e-15
YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 81 5e-15
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 81 5e-15
CE02604 [T] KOG0695 Serine/threonine protein kinase 81 5e-15
7296128 [T] KOG0583 Serine/threonine protein kinase 81 5e-15
YPL150w [T] KOG0583 Serine/threonine protein kinase 80 6e-15
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 80 6e-15
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 80 6e-15
Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 80 6e-15
CE21879 [D] KOG0590 Checkpoint kinase and related serine/threoni... 80 6e-15
CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 6e-15
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 80 8e-15
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 80 8e-15
At4g30960 [T] KOG0583 Serine/threonine protein kinase 80 8e-15
YPL209c [D] KOG0580 Serine/threonine protein kinase 80 1e-14
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 80 1e-14
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 80 1e-14
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 80 1e-14
Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing prot... 80 1e-14
Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing pro... 80 1e-14
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 80 1e-14
At3g50500 [T] KOG0583 Serine/threonine protein kinase 79 1e-14
7301734 [T] KOG0694 Serine/threonine protein kinase 79 1e-14
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 79 2e-14
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 79 2e-14
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 79 2e-14
CE17343 [T] KOG0583 Serine/threonine protein kinase 79 2e-14
At3g20860 [R] KOG0589 Serine/threonine protein kinase 79 2e-14
7300106 [T] KOG0690 Serine/threonine protein kinase 79 2e-14
YLR096w [T] KOG0583 Serine/threonine protein kinase 78 3e-14
Hs19923134 [T] KOG4250 TANK binding protein kinase TBK1 78 3e-14
CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase 78 3e-14
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 78 3e-14
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 78 4e-14
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 78 4e-14
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 78 4e-14
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 78 4e-14
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 78 4e-14
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 78 4e-14
At5g08590 [T] KOG0583 Serine/threonine protein kinase 78 4e-14
At1g54510 [R] KOG0589 Serine/threonine protein kinase 78 4e-14
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 77 5e-14
CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 77 5e-14
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 77 5e-14
7298926 [T] KOG0578 p21-activated serine/threonine protein kinase 77 5e-14
YAL017w [T] KOG1152 Signal transduction serine/threonine kinase ... 77 7e-14
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 77 7e-14
7299536 [D] KOG0580 Serine/threonine protein kinase 77 7e-14
7298698 [T] KOG4250 TANK binding protein kinase TBK1 77 7e-14
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 77 9e-14
YDR122w [T] KOG0583 Serine/threonine protein kinase 77 9e-14
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 77 9e-14
At5g01810 [T] KOG0583 Serine/threonine protein kinase 77 9e-14
At1g78290 [T] KOG0583 Serine/threonine protein kinase 77 9e-14
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 76 1e-13
CE21025 [D] KOG0580 Serine/threonine protein kinase 76 1e-13
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 76 1e-13
7302861 [T] KOG0696 Serine/threonine protein kinase 76 1e-13
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 76 1e-13
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 76 1e-13
SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine ki... 76 1e-13
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 76 1e-13
ECU08g1480 [R] KOG0586 Serine/threonine protein kinase 76 1e-13
YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 75 2e-13
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 75 2e-13
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 75 2e-13
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 75 2e-13
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 75 2e-13
YOR233w [T] KOG0583 Serine/threonine protein kinase 75 3e-13
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 75 3e-13
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 75 3e-13
YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and r... 75 3e-13
YBL105c [T] KOG0694 Serine/threonine protein kinase 75 3e-13
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 75 3e-13
CE05274 [T] KOG0690 Serine/threonine protein kinase 75 3e-13
7303915 [T] KOG0694 Serine/threonine protein kinase 75 3e-13
7303914 [T] KOG0694 Serine/threonine protein kinase 75 3e-13
CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 75 3e-13
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 74 4e-13
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 74 4e-13
CE15612 [T] KOG0690 Serine/threonine protein kinase 74 4e-13
CE15235 [R] KOG0589 Serine/threonine protein kinase 74 4e-13
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 74 4e-13
At4g32830 [D] KOG0580 Serine/threonine protein kinase 74 4e-13
At2g25880 [D] KOG0580 Serine/threonine protein kinase 74 4e-13
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 74 4e-13
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 74 4e-13
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 74 6e-13
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 74 6e-13
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 74 6e-13
Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase 74 7e-13
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 74 7e-13
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 74 7e-13
At1g60940 [T] KOG0583 Serine/threonine protein kinase 74 7e-13
7297611 [T] KOG0614 cGMP-dependent protein kinase 74 7e-13
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 74 7e-13
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 74 7e-13
7291742_1 [T] KOG0612 Rho-associated coiled-coil containing prot... 74 7e-13
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 73 1e-12
At5g63650 [T] KOG0583 Serine/threonine protein kinase 73 1e-12
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 73 1e-12
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 73 1e-12
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 73 1e-12
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 73 1e-12
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 73 1e-12
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 73 1e-12
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 73 1e-12
CE24761 [D] KOG0580 Serine/threonine protein kinase 73 1e-12
CE08098 [T] KOG0612 Rho-associated coiled-coil containing protei... 73 1e-12
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 73 1e-12
At1g45160 [TR] KOG0606 Microtubule-associated serine/threonine k... 73 1e-12
Hs16357474_1 [T] KOG0612 Rho-associated coiled-coil containing p... 73 1e-12
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 72 2e-12
Hs4505601 [T] KOG0578 p21-activated serine/threonine protein kinase 72 2e-12
CE29300 [T] KOG0694 Serine/threonine protein kinase 72 2e-12
CE29299 [T] KOG0694 Serine/threonine protein kinase 72 2e-12
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 72 2e-12
Hs7019547 [T] KOG4250 TANK binding protein kinase TBK1 72 2e-12
CE20564 [T] KOG0578 p21-activated serine/threonine protein kinase 72 2e-12
CE05425 [T] KOG0578 p21-activated serine/threonine protein kinase 72 2e-12
At1g10940 [T] KOG0583 Serine/threonine protein kinase 72 2e-12
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 72 3e-12
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 72 3e-12
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 72 3e-12
Hs4502803 [D] KOG0590 Checkpoint kinase and related serine/threo... 72 3e-12
CE12478 [D] KOG0590 Checkpoint kinase and related serine/threoni... 72 3e-12
At4g40010 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
At4g14580 [T] KOG0583 Serine/threonine protein kinase 72 3e-12
Hs7661946 [T] KOG4250 TANK binding protein kinase TBK1 71 4e-12
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 71 4e-12
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 71 4e-12
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 71 4e-12
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 71 5e-12
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 71 5e-12
CE28744 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 71 5e-12
7296166 [T] KOG0614 cGMP-dependent protein kinase 71 5e-12
7295638 [T] KOG0603 Ribosomal protein S6 kinase 71 5e-12
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 70 6e-12
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 70 6e-12
Hs4505831 [T] KOG0612 Rho-associated coiled-coil containing prot... 70 6e-12
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 70 6e-12
CE27899 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 6e-12
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 70 6e-12
CE19898 [T] KOG0614 cGMP-dependent protein kinase 70 6e-12
CE19897 [T] KOG0614 cGMP-dependent protein kinase 70 6e-12
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 70 6e-12
7300149 [T] KOG0578 p21-activated serine/threonine protein kinase 70 6e-12
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 70 8e-12
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 8e-12
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 70 8e-12
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 70 8e-12
7299793 [T] KOG0583 Serine/threonine protein kinase 70 8e-12
7293512 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 70 8e-12
YHR082c [T] KOG0583 Serine/threonine protein kinase 70 1e-11
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 70 1e-11
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 70 1e-11
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 70 1e-11
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 70 1e-11
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 69 1e-11
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 69 1e-11
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 69 1e-11
CE18699 [T] KOG0694 Serine/threonine protein kinase 69 1e-11
CE11916 [T] KOG0612 Rho-associated coiled-coil containing protei... 69 1e-11
7300098 [T] KOG4250 TANK binding protein kinase TBK1 69 1e-11
YHR102w [T] KOG0201 Serine/threonine protein kinase 69 2e-11
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 69 2e-11
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 69 2e-11
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 69 2e-11
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 69 2e-11
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 69 2e-11
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 69 2e-11
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 69 2e-11
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 69 2e-11
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 69 2e-11
Hs22057171 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 69 2e-11
Hs22046122 [OUT] KOG0595 Serine/threonine-protein kinase involve... 69 2e-11
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 69 2e-11
CE26076 [D] KOG0590 Checkpoint kinase and related serine/threoni... 69 2e-11
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 69 2e-11
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 69 2e-11
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 3e-11
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 68 3e-11
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 68 3e-11
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 68 3e-11
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 68 3e-11
At2g23030 [T] KOG0583 Serine/threonine protein kinase 68 3e-11
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 68 4e-11
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 68 4e-11
Hs14771959 [T] KOG0578 p21-activated serine/threonine protein ki... 68 4e-11
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 68 4e-11
CE20717 [T] KOG0583 Serine/threonine protein kinase 68 4e-11
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 68 4e-11
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 68 4e-11
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 68 4e-11
YOL045w [T] KOG1152 Signal transduction serine/threonine kinase ... 67 5e-11
Hs14993776 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 67 5e-11
Hs14749517 [T] KOG0192 Tyrosine kinase specific for activated (G... 67 5e-11
CE03979 [T] KOG0614 cGMP-dependent protein kinase 67 5e-11
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 67 5e-11
7294770 [T] KOG0603 Ribosomal protein S6 kinase 67 5e-11
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 67 5e-11
CE03609 [T] KOG0194 Protein tyrosine kinase 67 7e-11
7301213 [R] KOG0589 Serine/threonine protein kinase 67 7e-11
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 67 9e-11
Hs4502731 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 9e-11
Hs16950647 [R] KOG0663 Protein kinase PITSLRE and related kinases 67 9e-11
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 66 1e-10
YDR523c [T] KOG0201 Serine/threonine protein kinase 66 1e-10
SPCC576.15c [T] KOG0592 3-phosphoinositide-dependent protein kin... 66 1e-10
Hs5803088 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 66 1e-10
Hs10334852 [T] KOG0612 Rho-associated coiled-coil containing pro... 66 1e-10
CE03467 [T] KOG0604 MAP kinase-activated protein kinase 2 66 1e-10
Hs4505153 [T] KOG0198 MEKK and related serine/threonine protein ... 66 2e-10
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 66 2e-10
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 66 2e-10
CE23001 [R] KOG0589 Serine/threonine protein kinase 66 2e-10
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 66 2e-10
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 66 2e-10
CE01405 [T] KOG0577 Serine/threonine protein kinase 66 2e-10
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 66 2e-10
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 66 2e-10
At1g74740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 66 2e-10
7293249 [T] KOG0612 Rho-associated coiled-coil containing protei... 66 2e-10
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 65 2e-10
7297776 [D] KOG0580 Serine/threonine protein kinase 65 2e-10
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 65 3e-10
SPAC14C4.03 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 65 3e-10
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 65 3e-10
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 65 3e-10
Hs22068996 [T] KOG1345 Serine/threonine kinase 65 3e-10
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 65 3e-10
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 65 3e-10
YOR351c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 64 4e-10
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 64 4e-10
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 64 4e-10
Hs9910476 [T] KOG0578 p21-activated serine/threonine protein kinase 64 4e-10
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 64 4e-10
CE29466 [T] KOG0665 Jun-N-terminal kinase (JNK) 64 4e-10
At4g29810 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 64 4e-10
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 4e-10
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 64 4e-10
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 64 4e-10
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 64 6e-10
Hs14149671 [TR] KOG0606 Microtubule-associated serine/threonine ... 64 6e-10
CE20142 [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 64 6e-10
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 6e-10
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 6e-10
7303019 [Z] KOG0613 Projectin/twitchin and related proteins 64 6e-10
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 64 6e-10
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 64 8e-10
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 64 8e-10
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 64 8e-10
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 8e-10
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 64 8e-10
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 8e-10
At1g35670 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 64 8e-10
YOL113w [T] KOG0578 p21-activated serine/threonine protein kinase 63 1e-09
SPCC1259.13 [D] KOG0590 Checkpoint kinase and related serine/thr... 63 1e-09
Hs20543401 [TR] KOG0606 Microtubule-associated serine/threonine ... 63 1e-09
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 63 1e-09
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 63 1e-09
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 63 1e-09
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 63 1e-09
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 63 1e-09
CE25944 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 63 1e-09
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 63 1e-09
At4g13000 [R] KOG0610 Putative serine/threonine protein kinase 63 1e-09
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 63 1e-09
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 63 1e-09
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 63 1e-09
Hs6031180 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and... 63 1e-09
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 63 1e-09
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 63 1e-09
CE28993 [G] KOG0599 Phosphorylase kinase gamma subunit 63 1e-09
At3g56760 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 1e-09
At1g49580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 63 1e-09
7294566 [T] KOG0612 Rho-associated coiled-coil containing protei... 63 1e-09
YAR018c [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 62 2e-09
SPCC162.10 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 62 2e-09
Hs22045264 [T] KOG0583 Serine/threonine protein kinase 62 2e-09
CE17305 [T] KOG0665 Jun-N-terminal kinase (JNK) 62 2e-09
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 2e-09
At4g09570 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
At3g63260 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 2e-09
At3g22750 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 2e-09
Hs6005922_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 62 2e-09
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 62 2e-09
HsM5454184 [T] KOG4721 Serine/threonine protein kinase contains ... 62 2e-09
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 62 2e-09
Hs21735552 [T] KOG4721 Serine/threonine protein kinase contains ... 62 2e-09
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 62 2e-09
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 2e-09
SPBC16E9.13 [T] KOG0583 Serine/threonine protein kinase 62 3e-09
Hs17455844 [TR] KOG0606 Microtubule-associated serine/threonine ... 62 3e-09
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 62 3e-09
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 62 3e-09
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 62 3e-09
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 62 3e-09
CE23702 [T] KOG4721 Serine/threonine protein kinase contains leu... 62 3e-09
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 62 3e-09
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 62 3e-09
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 62 3e-09
At4g38470 [T] KOG0192 Tyrosine kinase specific for activated (GT... 62 3e-09
At4g36070 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 62 3e-09
YHL007c [T] KOG0578 p21-activated serine/threonine protein kinase 61 4e-09
Hs4505195 [T] KOG0192 Tyrosine kinase specific for activated (GT... 61 4e-09
Hs13129008 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 61 4e-09
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 4e-09
At3g19100 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 4e-09
7303804 [R] KOG0663 Protein kinase PITSLRE and related kinases 61 4e-09
7291707 [T] KOG1152 Signal transduction serine/threonine kinase ... 61 4e-09
YJL106w [T] KOG0661 MAPK related serine/threonine protein kinase 61 5e-09
YDL108w [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase... 61 5e-09
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 5e-09
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 5e-09
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 61 5e-09
At4g14780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 61 5e-09
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 61 5e-09
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 61 5e-09
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 61 5e-09
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 60 6e-09
Hs18602554 [T] KOG0578 p21-activated serine/threonine protein ki... 60 6e-09
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 60 6e-09
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 60 6e-09
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 6e-09
7293601 [T] KOG0577 Serine/threonine protein kinase 60 6e-09
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 60 6e-09
SPBC8D2.19 [T] KOG0661 MAPK related serine/threonine protein kinase 60 8e-09
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 60 8e-09
HsM4505263 [T] KOG0192 Tyrosine kinase specific for activated (G... 60 8e-09
Hs21735550 [T] KOG0192 Tyrosine kinase specific for activated (G... 60 8e-09
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 60 8e-09
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 60 8e-09
Hs17933758 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 60 8e-09
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 8e-09
At4g26070 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 60 8e-09
At1g73500 [T] KOG0581 Mitogen-activated protein kinase kinase (M... 60 8e-09
7291037 [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) 60 8e-09
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 60 8e-09
7289880 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 60 8e-09
Hs7705748 [T] KOG0192 Tyrosine kinase specific for activated (GT... 60 1e-08
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 60 1e-08
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 60 1e-08
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
At3g20410 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 60 1e-08
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 60 1e-08
7303860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 60 1e-08
YCR008w [D] KOG0590 Checkpoint kinase and related serine/threoni... 59 1e-08
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 59 1e-08
Hs15011880 [T] KOG0201 Serine/threonine protein kinase 59 1e-08
CE27410 [T] KOG0583 Serine/threonine protein kinase 59 1e-08
>YKL116c [R] KOG0586 Serine/threonine protein kinase
Length = 518
Score = 370 bits (951), Expect = e-102
Identities = 223/537 (41%), Positives = 314/537 (57%), Gaps = 75/537 (13%)
Query: 16 ETPKLAQREFAGGDAESS-VKNQLPEINSSLNREAIDVGMLPTPTANVFTSPVRVNKSPG 74
E K+A E GD+ S+ + +P + V LPTP SP ++ SP
Sbjct: 40 EDKKMASTEGTTGDSRSTPLTVSIPTFEN--------VQALPTPMTYTPLSPGNLSMSPI 91
Query: 75 GFDAGLQVEKRRNKDSASNSGVPSPTISSVDTHEEVLDEELSKLGTYMNRDVTHKIKGRM 134
+ L + KRR+ H +LD+ LS T N+ R+
Sbjct: 92 D-QSSLNIPKRRS-------------------HARLLDDMLSV--TQPNQ--------RV 121
Query: 135 LSEYIPNNSMGDGSGGVAVQRSISLNNRVVEKPSLKKETIINEVITS--------VPSDK 186
+SE I ++ RVV P++ +E ++N+ + S P
Sbjct: 122 VSELIAPANLSP--------------QRVVSLPTVTEEALVNDSVDSDNYTKEPYFPESS 167
Query: 187 ENEQKADGTIIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKY 246
+ +K D I +G++ + + W K++ IGSGNFSTV LYE +D + NP+LK
Sbjct: 168 SSTEKCDDDIFQGFLLDHWDR-PLLWKKVRPIGSGNFSTVLLYELMDQS-----NPKLKQ 221
Query: 247 VAVKSIKYPRELL-MSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTT 305
VAVK +KYP EL + +S +YKE LSR+ +SL REL L S++HPCIVKL IN+
Sbjct: 222 VAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPI 281
Query: 306 FITDEHPLYGR--RKLSALPRCDMIMSYCTGGDLFD--LASKTKIPNWLLTRIITELSVA 361
F+T + PL + ALP CDMIMSYC GDL +A ++ WL+ RI TE+ +A
Sbjct: 282 FVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLA 341
Query: 362 IKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM 421
+KYLH+N IIHRD+KLEN+LLKY+ DD+ + D + +NF+ELADFGLCKKI +EM
Sbjct: 342 VKYLHENSIIHRDLKLENILLKYSFDDINSFR-DSPIYCKQNFIELADFGLCKKIENNEM 400
Query: 422 CTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSR-RTRSI 480
CT RCGSEDYVSPEIL+G+PYDG +SD WA GVI Y+L EDRLPFDP P S+R R+R+
Sbjct: 401 CTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPPPNASARQRSRAT 460
Query: 481 AHRIARCDWKWLKNAD-TDHPAKEIVQNTLVRKSERWNMDQLCNTPYIRNIIDKLQF 536
+HRIAR DW+W + +D + K+IV+NTL RK++RW+++++ +P+++ I D L F
Sbjct: 461 SHRIARFDWRWYRLSDYKTNVGKQIVENTLTRKNQRWSINEIYESPFVKTIADTLSF 517
>SPBC337.04 [R] KOG0586 Serine/threonine protein kinase
Length = 413
Score = 120 bits (300), Expect = 7e-27
Identities = 74/266 (27%), Positives = 133/266 (49%), Gaps = 30/266 (11%)
Query: 235 NLNINLNPELKYVAVKSI--KYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHH 292
N I + + + VKS K+ +++ + S K + V ++E+ L ++ H
Sbjct: 105 NTKITSTEQREVLLVKSNNKKFDTSIVLKHTHLSSKSQNEKKARVKVFRQEIWALKTLSH 164
Query: 293 PCIVKL--FAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLASK--TKIPN 348
PC+V+L + ++ I ++ +YC GGDL+ K +
Sbjct: 165 PCVVQLLNYYVSSAELI-------------------LVENYCMGGDLYHYTKKHHSDFSL 205
Query: 349 WLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELA 408
+ RI +EL + YLH +IHRD+KLEN+LL + + + D + + ++++
Sbjct: 206 EFVGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTI--DNWKNYPNALIQIS 263
Query: 409 DFGLCKKI-TPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFD 467
DF L + + + + + CGS++Y PE+ +G+ +DG +DAW+ G++ +ALLE RLPFD
Sbjct: 264 DFELSIFVDSKNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPFD 323
Query: 468 PLP--GQSSRRTRSIAHRIARCDWKW 491
P + R + R+ RCD+ W
Sbjct: 324 SYPTLDPENVRIKRYVQRLVRCDYTW 349
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 110 bits (275), Expect = 5e-24
Identities = 107/371 (28%), Positives = 166/371 (43%), Gaps = 89/371 (23%)
Query: 158 SLNNRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIRGY----MANTPNHISFQWS 213
+LN R E+P+L + S PS K N +IRG A+ HI +
Sbjct: 10 TLNERDTEQPTLGH-------LDSKPSSKSN-------MIRGRNSATSADEQPHIG-NYR 54
Query: 214 KIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELL 273
+K IG GNF+ V L I K VAVK I + L SSS
Sbjct: 55 LLKTIGKGNFAKVKLARHILTG---------KEVAVKIID--KTQLNSSS---------- 93
Query: 274 SRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
+ L RE+ + ++HP IVKLF + +T E LY ++M Y +
Sbjct: 94 ---LQKLFREVRIMKVLNHPNIVKLFEVIET-----EKTLY------------LVMEYAS 133
Query: 334 GGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
GG++FD L + ++ ++ A++Y H FI+HRD+K EN+LL ++
Sbjct: 134 GGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMN----- 188
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
+++ADFG + T T CGS Y +PE+ G YDG D W+
Sbjct: 189 ------------IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 236
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWK--WLKNADTDHPAKEIVQNTLV 510
GVI Y L+ LPFD GQ+ + R R+ R ++ + + D ++ K+ + ++
Sbjct: 237 GVILYTLVSGSLPFD---GQNLKELR---ERVLRGKYRIPFYMSTDCENLLKKFL---IL 287
Query: 511 RKSERWNMDQL 521
S+R ++Q+
Sbjct: 288 NPSKRGTLEQI 298
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 108 bits (270), Expect = 2e-23
Identities = 102/351 (29%), Positives = 148/351 (42%), Gaps = 84/351 (23%)
Query: 138 YIPNNSMGDG----SGGVAVQRSISLNNRVVEKPSLKKETIINEVITSVPSD-----KEN 188
++ NN DG S AV S ++N+ P +N+ + S S K+
Sbjct: 62 HVANNMTTDGARLSSNNSAVVASSAINHHHHHTPGSGVAPTVNKNVLSTHSAHPSAIKQR 121
Query: 189 EQKADGTIIRGYMANTP-------NHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLN 241
A G+ ++ P HI ++ IK IG GNF+ V L + +
Sbjct: 122 TSSAKGSPNMQMRSSAPMRWRATEEHIG-KYKLIKTIGKGNFAKVKLAKHL--------- 171
Query: 242 PELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAI 301
P K VA+K I + +P S + L RE+ + + HP IVKLF +
Sbjct: 172 PTGKEVAIKIIDKTQ-----LNPGS----------LQKLFREVRIMKMLDHPNIVKLFQV 216
Query: 302 NDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLA-----SKTKIPNWLLTRIIT 356
+T E LY +IM Y +GG++FD K K +I++
Sbjct: 217 IET-----EKTLY------------LIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVS 259
Query: 357 ELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKI 416
A++Y H IIHRD+K EN+LL L+ +++ADFG +
Sbjct: 260 ----AVQYCHQKRIIHRDLKAENLLLDSELN-----------------IKIADFGFSNEF 298
Query: 417 TPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFD 467
TP T CGS Y +PE+ G YDG D W+ GVI Y L+ LPFD
Sbjct: 299 TPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD 349
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 107 bits (266), Expect = 6e-23
Identities = 103/408 (25%), Positives = 172/408 (41%), Gaps = 111/408 (27%)
Query: 139 IPNNSMGDGSGGVAVQRSISLNNRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIR 198
IP + + + G+A ++ +NN + L++ + E+I S+
Sbjct: 39 IPQDQIDNIMSGIANTGNVKMNNH---RKKLRQRKVAPELIESI---------------- 79
Query: 199 GYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPEL-KYVAVKSIKYPRE 257
++ IK++G G + V L +N E + VA+K+IK
Sbjct: 80 -----------LKFDIIKKLGQGTYGKVQL----------GINKETGQEVAIKTIK---- 114
Query: 258 LLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRR 317
K K + ++RE+ + SVHHP I+ ++ + + R
Sbjct: 115 ----------KCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFEN-----------RE 153
Query: 318 KLSALPRCDMIMSYCTGGDLFDLASKTKI-PNWLLTRIITELSVAIKYLHDNFIIHRDIK 376
K+ ++M + GG+L+D S+ K+ RI +++ A+ Y H + I HRD+K
Sbjct: 154 KMV------LVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLK 207
Query: 377 LENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEI 436
LEN+LL DE K ++ADFGL + T CGS Y SPEI
Sbjct: 208 LENILL------------DE-----KGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEI 250
Query: 437 LLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNAD 496
+ G PY G D W+ GV+ Y L+ +PFD G + +R K + D
Sbjct: 251 VEGTPYQGPEVDCWSLGVLLYTLVYGSMPFD---GSNFKRL-----------VKQISQGD 296
Query: 497 TDHPAKEIVQNTLVR------KSERWNMDQLCNTPYIRNIIDKLQFLD 538
P K +TL+R +R +++Q+C+ ++ N D + LD
Sbjct: 297 YYEPRKPSRASTLIRDMLTVCPRKRASIEQICSHWWV-NENDNVSCLD 343
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 104 bits (260), Expect = 3e-22
Identities = 90/310 (29%), Positives = 142/310 (45%), Gaps = 70/310 (22%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K IG GNF+ V L I K VAVK I + L SSS
Sbjct: 23 LKTIGKGNFAKVKLARHILTG---------KEVAVKIID--KTQLNSSS----------- 60
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ L RE+ + ++HP IVKLF + +T E LY ++M Y +G
Sbjct: 61 --LQKLFREVRIMKVLNHPNIVKLFEVIET-----EKTLY------------LVMEYASG 101
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G++FD L + ++ ++ A++Y H FI+HRD+K EN+LL ++
Sbjct: 102 GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMN------ 155
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ADFG + T T CGS Y +PE+ G YDG D W+ G
Sbjct: 156 -----------IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 204
Query: 454 VITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWK--WLKNADTDHPAKEIVQNTLVR 511
VI Y L+ LPFD GQ+ + R R+ R ++ + + D ++ K+ + ++
Sbjct: 205 VILYTLVSGSLPFD---GQNLKELR---ERVLRGKYRIPFYMSTDCENLLKKFL---ILN 255
Query: 512 KSERWNMDQL 521
S+R ++Q+
Sbjct: 256 PSKRGTLEQI 265
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 104 bits (260), Expect = 3e-22
Identities = 90/310 (29%), Positives = 142/310 (45%), Gaps = 70/310 (22%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K IG GNF+ V L I K VAVK I + L SSS
Sbjct: 23 LKTIGKGNFAKVKLARHILTG---------KEVAVKIID--KTQLNSSS----------- 60
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ L RE+ + ++HP IVKLF + +T E LY ++M Y +G
Sbjct: 61 --LQKLFREVRIMKVLNHPNIVKLFEVIET-----EKTLY------------LVMEYASG 101
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G++FD L + ++ ++ A++Y H FI+HRD+K EN+LL ++
Sbjct: 102 GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMN------ 155
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ADFG + T T CGS Y +PE+ G YDG D W+ G
Sbjct: 156 -----------IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 204
Query: 454 VITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWK--WLKNADTDHPAKEIVQNTLVR 511
VI Y L+ LPFD GQ+ + R R+ R ++ + + D ++ K+ + ++
Sbjct: 205 VILYTLVSGSLPFD---GQNLKELR---ERVLRGKYRIPFYMSTDCENLLKKFL---ILN 255
Query: 512 KSERWNMDQL 521
S+R ++Q+
Sbjct: 256 PSKRGTLEQI 265
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 104 bits (259), Expect = 4e-22
Identities = 66/237 (27%), Positives = 119/237 (49%), Gaps = 39/237 (16%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ + ++HP +++L+ + +T TD LY +++ Y G+LF+
Sbjct: 78 IEREIIIMKLLNHPNVLRLYDVWETN--TD---LY------------LVLEYAEKGELFN 120
Query: 340 L-ASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
L + +P R ++ + + Y H I+HRD+K EN+LL +
Sbjct: 121 LLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDH-------------- 166
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
K +++ADFG+ T ++ T CGS Y +PEI+ G+PY G SD W+ GVI +A
Sbjct: 167 ---KYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFA 223
Query: 459 LLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRKSER 515
LL RLPFD G R++ ++ + +++ + + A+++++ L ER
Sbjct: 224 LLTGRLPFDEEDG----NIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPER 276
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 102 bits (254), Expect = 1e-21
Identities = 65/193 (33%), Positives = 94/193 (48%), Gaps = 35/193 (18%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
VV +KRE+ L HP I+KL+ + T TD M+M Y +GG
Sbjct: 57 VVGKIKREIQNLKLFRHPHIIKLYQVISTP--TDFF---------------MVMEYVSGG 99
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LFD K ++ R+ ++ A+ Y H + ++HRD+K ENVLL ++
Sbjct: 100 ELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMN------- 152
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++ADFGL ++ E T CGS +Y +PE++ G Y G D W+ GV
Sbjct: 153 ----------AKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGRLYAGPEVDIWSCGV 202
Query: 455 ITYALLEDRLPFD 467
I YALL LPFD
Sbjct: 203 ILYALLCGTLPFD 215
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 102 bits (253), Expect = 2e-21
Identities = 65/192 (33%), Positives = 94/192 (48%), Gaps = 38/192 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
+KRE+ TL + HP IV+L + L++ + +M+M TGG+LFD
Sbjct: 65 IKREIRTLKMLKHPHIVRLHEV-----------------LASKTKINMVMELVTGGELFD 107
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ S K+ ++ +L I Y H + HRD+KLENVLL
Sbjct: 108 RIVSNGKLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLD--------------- 152
Query: 399 FFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+K +++ DFGL + D + T CGS +YV+PE+L YDG SD W+ GVI
Sbjct: 153 --AKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVI 210
Query: 456 TYALLEDRLPFD 467
Y +L LPFD
Sbjct: 211 LYVILTGCLPFD 222
>At1g48260 [T] KOG0583 Serine/threonine protein kinase
Length = 432
Score = 102 bits (253), Expect = 2e-21
Identities = 65/192 (33%), Positives = 95/192 (48%), Gaps = 38/192 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
+KRE+ TL + HP IV+L + L++ + M++ TGGDLFD
Sbjct: 56 IKREIRTLKVLKHPNIVRLHEV-----------------LASKTKIYMVLECVTGGDLFD 98
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ SK K+ ++ +L + Y H+ + HRD+KLENVLL
Sbjct: 99 RIVSKGKLSETQGRKMFQQLIDGVSYCHNKGVFHRDLKLENVLLD--------------- 143
Query: 399 FFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+K +++ DFGL + D + T CGS +YV+PE+L YDG SD W+ GVI
Sbjct: 144 --AKGHIKITDFGLSALSQHYREDGLLHTTCGSPNYVAPEVLANEGYDGAASDIWSCGVI 201
Query: 456 TYALLEDRLPFD 467
Y +L LPFD
Sbjct: 202 LYVILTGCLPFD 213
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 102 bits (253), Expect = 2e-21
Identities = 88/335 (26%), Positives = 146/335 (43%), Gaps = 78/335 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K++GSG + V L D + + VAVK IK S+ + K L R
Sbjct: 79 KKLGSGTYGKVSL--AYDHKFD-------REVAVKLIK----------KSAIESKADLVR 119
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ +RE+ + +++HP I++++ + + + ++M Y +GG
Sbjct: 120 I----RREIRIMSALNHPNIIQIYEVFENK-----------------DKIILVMEYSSGG 158
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+L+D S+ +P RI +++ A+ Y H + + HRD+KLEN+LL
Sbjct: 159 ELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHRVAHRDLKLENILLD----------- 207
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
N ++ADFGL + TT CGS Y SPEI+ G PY G D W+ G+
Sbjct: 208 ------QNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKGPEVDCWSLGI 261
Query: 455 ITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRKSE 514
+ Y L+ +PFD R + +I R + +T A +++N L E
Sbjct: 262 LLYTLVYGSMPFD------GRDFNRMVRQIKRGAY---FEPETPSTASMLIRNMLRVNPE 312
Query: 515 R----------WNMDQLCNTPYIRNIIDKLQFLDH 539
R W ++ N P I+ + + Q +DH
Sbjct: 313 RRATIFDIASHWWLNLEENMPVIQELPEN-QIIDH 346
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 100 bits (250), Expect = 4e-21
Identities = 64/193 (33%), Positives = 91/193 (46%), Gaps = 35/193 (18%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
VV ++RE+ L HP I+KL+ + +S MIM Y +GG
Sbjct: 69 VVGKIRREIQNLKLFRHPHIIKLYQV-----------------ISTPSDIFMIMEYVSGG 111
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LFD K K+ R ++ + Y H + I+HRD+K EN+LL + +
Sbjct: 112 ELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMH------- 164
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
V++ADFGL + E T CGS +Y +PE++ G Y G D W+ GV
Sbjct: 165 ----------VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGV 214
Query: 455 ITYALLEDRLPFD 467
I YALL LPFD
Sbjct: 215 ILYALLCGTLPFD 227
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 100 bits (248), Expect = 7e-21
Identities = 76/254 (29%), Positives = 112/254 (43%), Gaps = 59/254 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
IK +G GNF+ V L + P + VA+K I +L +
Sbjct: 101 IKTLGKGNFAKVKLAIHV---------PTGREVAIKVIDKT---------------QLNT 136
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
L RE+ + ++HP IV+LF + I E LY ++M Y +
Sbjct: 137 SARQKLYREVKIMKLLNHPNIVRLFQV-----IESERTLY------------LVMEYASR 179
Query: 335 GDLFDLASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LFD K R+I +L AI+Y H F++HRD+K EN+LL ++
Sbjct: 180 GELFDHLVKNGRMRERDARVIFRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMN------ 233
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ADFG P+ T CGS Y +PE+ +G Y G DAW+ G
Sbjct: 234 -----------IKIADFGFGNTFDPNAQLETFCGSPPYAAPELFMGRKYAGPEVDAWSLG 282
Query: 454 VITYALLEDRLPFD 467
V+ Y L+ LPFD
Sbjct: 283 VVLYTLVSGSLPFD 296
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 99.8 bits (247), Expect = 1e-20
Identities = 72/254 (28%), Positives = 116/254 (45%), Gaps = 60/254 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K +G G F+ VYL + I VA+K I K K + S
Sbjct: 78 KLLGHGTFAKVYLAQNIKSG---------DKVAIKVID--------------KEKIMKSG 114
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+V+ +KRE++ L V HP IV LF + T + +Y +M Y GG
Sbjct: 115 LVAHIKREISILRRVRHPYIVHLFEVMAT-----KSKIY------------FVMEYVGGG 157
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LF+ +K ++P R +L ++ + H + HRD+K EN+LL
Sbjct: 158 ELFNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLD------------ 205
Query: 396 ESQFFSKNFVELADFGL---CKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
+K ++++DFGL +++ D +C T CG+ Y++PE+L YD +D W+
Sbjct: 206 -----NKGNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKADVWSC 260
Query: 453 GVITYALLEDRLPF 466
GVI + L+ +PF
Sbjct: 261 GVILFVLMAGHIPF 274
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 99.4 bits (246), Expect = 1e-20
Identities = 64/233 (27%), Positives = 114/233 (48%), Gaps = 39/233 (16%)
Query: 279 SLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF 338
+++RE+ + + HP ++ L+ + +T + LY +I+ Y G+LF
Sbjct: 73 NIEREIVIMKLLSHPNVLSLYDVWETN-----NNLY------------LILEYAEKGELF 115
Query: 339 DL-ASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+L +P ++ + I Y H I+HRD+K EN+LL
Sbjct: 116 NLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLL--------------D 161
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
F++ +++ADFG+ T ++ T CGS Y +PEI+ GLPY+G SD W+ GVI +
Sbjct: 162 SFYN---IKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILF 218
Query: 458 ALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLV 510
ALL RLPFD + + R + ++ + ++ + + A++++ LV
Sbjct: 219 ALLTGRLPFD----EENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILV 267
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 99.4 bits (246), Expect = 1e-20
Identities = 64/199 (32%), Positives = 98/199 (49%), Gaps = 35/199 (17%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
++L V+ ++RE+ L + HP ++KL H +Y +K L ++
Sbjct: 85 EKLSESVLMKVEREIAILKLIEHPHVLKL------------HDVYENKKYLYL-----VL 127
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
+ +GG+LFD L K ++ + ++ A+ + H I HRD+K EN+LL
Sbjct: 128 EHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLL------ 181
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
DE KN + +ADFG+ D + T CGS Y PE++ G YDGR +D
Sbjct: 182 ------DE-----KNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRAD 230
Query: 449 AWAFGVITYALLEDRLPFD 467
W+ GVI +ALL LPFD
Sbjct: 231 MWSCGVILFALLVGALPFD 249
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 99.0 bits (245), Expect = 2e-20
Identities = 78/264 (29%), Positives = 119/264 (44%), Gaps = 62/264 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K IG GNF+ V L + + VAVK I + +P+S
Sbjct: 64 KTIGKGNFAKVKLARHVLTG---------REVAVKIIDKTQ-----LNPTS--------- 100
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ L RE+ + ++HP IVKLF + +T E LY ++M Y +GG
Sbjct: 101 -LQKLFREVRIMKILNHPNIVKLFEVIET-----EKTLY------------LVMEYASGG 142
Query: 336 DLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
++FD L + ++ ++ A++Y H +I+HRD+K EN+LL ++
Sbjct: 143 EVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN------- 195
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
+++ADFG + T T CGS Y +PE+ G YDG D W+ GV
Sbjct: 196 ----------IKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGV 245
Query: 455 ITYALLEDRLPFDPLPGQSSRRTR 478
I Y L+ LPFD GQ+ + R
Sbjct: 246 ILYTLVSGSLPFD---GQNLKELR 266
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 98.6 bits (244), Expect = 2e-20
Identities = 61/193 (31%), Positives = 92/193 (47%), Gaps = 35/193 (18%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
VV ++RE+ L HP I+KL+ + +S M+M Y +GG
Sbjct: 59 VVGKIRREIQNLKLFRHPHIIKLYQV-----------------ISTPSDIFMVMEYVSGG 101
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LFD K ++ R+ ++ + Y H + ++HRD+K ENVLL ++
Sbjct: 102 ELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMN------- 154
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++ADFGL ++ E T CGS +Y +PE++ G Y G D W+ GV
Sbjct: 155 ----------AKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGV 204
Query: 455 ITYALLEDRLPFD 467
I YALL LPFD
Sbjct: 205 ILYALLCGTLPFD 217
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 98.6 bits (244), Expect = 2e-20
Identities = 74/251 (29%), Positives = 117/251 (46%), Gaps = 59/251 (23%)
Query: 217 EIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRV 276
EIGSGNFS V L I+ + K VA+K ++ + K + LLSR
Sbjct: 79 EIGSGNFSQV--------KLGIHSLTKEK-VAIK--------ILDKTKLDQKTQRLLSRE 121
Query: 277 VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGD 336
+SS+++ +HHP I++L+ + +T L + ++M Y GG+
Sbjct: 122 ISSMEK-------LHHPNIIRLYEVVET-----------------LSKLHLVMEYAGGGE 157
Query: 337 LFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
LF ++++ K+ I +++ A+K++H+N IIHRD+K ENV
Sbjct: 158 LFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVF-------------- 203
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+ S V++ DFG EM T CGS Y +PE+ Y G D WA GV+
Sbjct: 204 ---YTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVL 260
Query: 456 TYALLEDRLPF 466
Y ++ +PF
Sbjct: 261 LYFMVTGTMPF 271
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 97.4 bits (241), Expect = 5e-20
Identities = 63/193 (32%), Positives = 94/193 (48%), Gaps = 35/193 (18%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
VV ++RE+ L HP I++L+ + +S MIM + +GG
Sbjct: 66 VVGKIRREIQNLSLFRHPHIIRLYQV-----------------ISTPSDIFMIMEHVSGG 108
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LFD K ++ R ++ + Y H + ++HRD+K EN+LL
Sbjct: 109 ELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLLL------------ 156
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
DE +N V++ADFGL +T + T CGS +Y +PE++ G Y G D W+ GV
Sbjct: 157 DE-----QNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGV 211
Query: 455 ITYALLEDRLPFD 467
I YALL LPFD
Sbjct: 212 ILYALLCGTLPFD 224
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 97.4 bits (241), Expect = 5e-20
Identities = 63/193 (32%), Positives = 94/193 (48%), Gaps = 35/193 (18%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
VV ++RE+ L HP I++L+ + +S MIM + +GG
Sbjct: 66 VVGKIRREIQNLSLFRHPHIIRLYQV-----------------ISTPSDIFMIMEHVSGG 108
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LFD K ++ R ++ + Y H + ++HRD+K EN+LL
Sbjct: 109 ELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRDLKPENLLL------------ 156
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
DE +N V++ADFGL +T + T CGS +Y +PE++ G Y G D W+ GV
Sbjct: 157 DE-----QNNVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGV 211
Query: 455 ITYALLEDRLPFD 467
I YALL LPFD
Sbjct: 212 ILYALLCGTLPFD 224
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 97.1 bits (240), Expect = 6e-20
Identities = 77/269 (28%), Positives = 120/269 (43%), Gaps = 62/269 (23%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
++ +K IG GNF+ V L + + VA+K I + +PSS
Sbjct: 121 KYKLLKTIGKGNFAKVKLAKHVITGHE---------VAIKIIDKT-----ALNPSS---- 162
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+ L RE+ + + HP IVKL+ + +T E LY +++
Sbjct: 163 ------LQKLFREVKIMKQLDHPNIVKLYQVMET-----EQTLY------------LVLE 199
Query: 331 YCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
Y +GG++FD L + ++ ++ A++YLH IIHRD+K EN+LL ++
Sbjct: 200 YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMN-- 257
Query: 390 MLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDA 449
+++ADFG + T CGS Y +PE+ G YDG D
Sbjct: 258 ---------------IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDV 302
Query: 450 WAFGVITYALLEDRLPFDPLPGQSSRRTR 478
W+ GVI Y L+ LPFD GQ+ + R
Sbjct: 303 WSLGVILYTLVSGSLPFD---GQNLKELR 328
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 97.1 bits (240), Expect = 6e-20
Identities = 77/269 (28%), Positives = 120/269 (43%), Gaps = 62/269 (23%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
++ +K IG GNF+ V L + + VA+K I + +PSS
Sbjct: 169 KYKLLKTIGKGNFAKVKLAKHVITGHE---------VAIKIIDKT-----ALNPSS---- 210
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+ L RE+ + + HP IVKL+ + +T E LY +++
Sbjct: 211 ------LQKLFREVKIMKQLDHPNIVKLYQVMET-----EQTLY------------LVLE 247
Query: 331 YCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
Y +GG++FD L + ++ ++ A++YLH IIHRD+K EN+LL ++
Sbjct: 248 YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMN-- 305
Query: 390 MLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDA 449
+++ADFG + T CGS Y +PE+ G YDG D
Sbjct: 306 ---------------IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDV 350
Query: 450 WAFGVITYALLEDRLPFDPLPGQSSRRTR 478
W+ GVI Y L+ LPFD GQ+ + R
Sbjct: 351 WSLGVILYTLVSGSLPFD---GQNLKELR 376
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 97.1 bits (240), Expect = 6e-20
Identities = 75/271 (27%), Positives = 123/271 (44%), Gaps = 64/271 (23%)
Query: 201 MANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLM 260
M N P+ ++ ++ + +G G F+ VY I N + VA+K I
Sbjct: 1 MENKPSVLTDKYDVGRLLGQGTFAKVYYGRSILTNQS---------VAIKMID------- 44
Query: 261 SSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLS 320
K K + ++ +KRE++ + HP +V+L+ + ++
Sbjct: 45 -------KEKVMKVGLIEQIKREISVMRIARHPNVVELYEV-----------------MA 80
Query: 321 ALPRCDMIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENV 380
R +M YC GG+LF+ +K K+ + + + +L A+ + H + HRDIK EN+
Sbjct: 81 TKTRIYFVMEYCKGGELFNKVAKGKLRDDVAWKYFYQLINAVDFCHSREVYHRDIKPENL 140
Query: 381 LLKYTLDDMMLLKEDESQFFSKNFVELADFGL-----CKKITPDEMCTTRCGSEDYVSPE 435
L LDD LK ++DFGL CK+ D + T CG+ YV+PE
Sbjct: 141 L----LDDNENLK-------------VSDFGLSALADCKR--QDGLLHTTCGTPAYVAPE 181
Query: 436 ILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
++ YDG +D W+ GV+ + LL LPF
Sbjct: 182 VINRKGYDGTKADIWSCGVVLFVLLAGYLPF 212
>CE16081 [T] KOG0583 Serine/threonine protein kinase
Length = 334
Score = 96.7 bits (239), Expect = 8e-20
Identities = 72/252 (28%), Positives = 115/252 (45%), Gaps = 59/252 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
KE+G+GNFS V L ++ + K VAVK +M + K ++LLSR
Sbjct: 53 KELGAGNFSKV--------KLGVHQLTKEK-VAVK--------IMDKAKMDAKAQKLLSR 95
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ +++ ++HP IVKLF + +T L R +++ Y +GG
Sbjct: 96 EIQAMEE-------MNHPNIVKLFEVVET-----------------LTRVHLVIEYASGG 131
Query: 336 DLFDLA-SKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+L+ + K+ + ++ A+ ++H I+HRDIK ENV+
Sbjct: 132 ELYTYVHERGKLTEGDAKPLFAQIVSAVSHMHSRNIVHRDIKAENVM------------- 178
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
F S N V+L DFG + ++M T CGS Y +PE+ Y G + D WA GV
Sbjct: 179 ----FSSPNTVKLVDFGFSCLVDREQMLRTFCGSPPYAAPELFQDTSYAGELVDVWALGV 234
Query: 455 ITYALLEDRLPF 466
+ + +L PF
Sbjct: 235 LLFFMLIGVTPF 246
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 96.7 bits (239), Expect = 8e-20
Identities = 80/255 (31%), Positives = 112/255 (43%), Gaps = 61/255 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
IK +G GNF+ V L I+L P + VA+K I K L+
Sbjct: 66 IKTLGKGNFAKV--------KLAIHL-PTGREVAIKLID----------------KTALN 100
Query: 275 RVV-SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
+ L RE+ + ++HP IV+L + I E LY ++M Y +
Sbjct: 101 TIARQKLYREVNIMKKLNHPNIVRLLQV-----IESERTLY------------LVMEYVS 143
Query: 334 GGDLFDLASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
GG+LF+ K R++ +L AI+Y H I+HRD+K EN+LL D M L
Sbjct: 144 GGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLL----DQQMKL 199
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
K +ADFG P T CGS Y +PE+ G Y G D+W+
Sbjct: 200 K-------------IADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSL 246
Query: 453 GVITYALLEDRLPFD 467
GV+ Y L+ LPFD
Sbjct: 247 GVVLYTLVSGSLPFD 261
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 96.3 bits (238), Expect = 1e-19
Identities = 83/322 (25%), Positives = 141/322 (43%), Gaps = 79/322 (24%)
Query: 149 GGVAVQRSISLNNRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMANTPNHI 208
G +Q L R+V K + K+ TS P + + G+I+
Sbjct: 13 GPTPIQFMAGLLARIVTKNTNKE--------TSTPESPRSPRTPQGSILMD--------- 55
Query: 209 SFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPK 268
++ K +G G+F+ VYL NI+ + VA+K I K
Sbjct: 56 --KYEIGKLLGHGSFAKVYLAR------NIHSGED---VAIKVID--------------K 90
Query: 269 YKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMI 328
K + S + +KRE++ L V HP IV L + ++ + ++
Sbjct: 91 EKIVKSGLAGHIKREISILRRVRHPYIVHLLEV-----------------MATKTKIYIV 133
Query: 329 MSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
M Y GG+L++ ++ ++ R +L ++ + H + HRD+KLEN+LL DD
Sbjct: 134 MEYVRGGELYNTVARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLL----DD 189
Query: 389 MMLLKEDESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
K V+++DFGL +++ + +C T CG+ Y++PE+L Y+G
Sbjct: 190 -------------KGNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEGA 236
Query: 446 ISDAWAFGVITYALLEDRLPFD 467
+D W+ GVI + L+ LPFD
Sbjct: 237 KADIWSCGVILFVLMAGYLPFD 258
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 95.9 bits (237), Expect = 1e-19
Identities = 60/189 (31%), Positives = 94/189 (48%), Gaps = 35/189 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ + S++HP I+ ++ + + + +IM Y + G+L+D
Sbjct: 100 IRREIEIMSSLNHPHIISIYEVFENK-----------------DKIVIIMEYASKGELYD 142
Query: 340 LASKTKIPNWLLTR-IITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
S+ + + TR ++ A+ Y H N ++HRD+KLEN+LL DD +K
Sbjct: 143 YISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILL----DDNCNIK----- 193
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+ADFGL D+ T CGS Y SPEI+ G PY G D+WA GV+ Y
Sbjct: 194 --------IADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYT 245
Query: 459 LLEDRLPFD 467
L+ +PFD
Sbjct: 246 LVYGTMPFD 254
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 95.5 bits (236), Expect = 2e-19
Identities = 74/253 (29%), Positives = 113/253 (44%), Gaps = 59/253 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K IG GNF+ V L N+ + K VA+K I + +E L++
Sbjct: 45 KTIGKGNFAVV--------KLATNIVTKTK-VAIKIID-----------KTCLNEEYLNK 84
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
RE+ L S+ HP I +L+ + ++ + +Y ++ Y G
Sbjct: 85 TF----REIAILKSLRHPHITRLYEVMES-----QSMIY------------LVTEYAPNG 123
Query: 336 DLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
++FD L + ++ R+ T+L A+ Y H ++HRD+K ENVLL ++
Sbjct: 124 EIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMN------- 176
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++LADFG T CGS Y +PE+ GL YDG SD W+ GV
Sbjct: 177 ----------IKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGV 226
Query: 455 ITYALLEDRLPFD 467
+ YAL+ LPFD
Sbjct: 227 VLYALVCGALPFD 239
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 95.1 bits (235), Expect = 2e-19
Identities = 78/265 (29%), Positives = 118/265 (44%), Gaps = 62/265 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K IG GNF+ V L I + VA+K I + +P+S
Sbjct: 59 LKTIGKGNFAKVKLARHILTG---------REVAIKIIDKTQ-----LNPTS-------- 96
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ L RE+ + ++HP IVKLF + +T + LY +IM Y +G
Sbjct: 97 --LQKLFREVRIMKILNHPNIVKLFEVIET-----QKTLY------------LIMEYASG 137
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G +FD L + ++ ++ A++Y H I+HRD+K EN+LL ++
Sbjct: 138 GKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMN------ 191
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ADFG + T T CGS Y +PE+ G YDG D W+ G
Sbjct: 192 -----------IKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 240
Query: 454 VITYALLEDRLPFDPLPGQSSRRTR 478
VI Y L+ LPFD GQ+ + R
Sbjct: 241 VILYTLVSGSLPFD---GQNLKELR 262
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/262 (30%), Positives = 124/262 (46%), Gaps = 42/262 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
KE L S++ E+ L + HP IV L D + + H LY +IM
Sbjct: 53 KEALEGKEGSMENEIAVLHKIKHPNIVAL----DDIYESGGH-LY------------LIM 95
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
+GG+LFD + K +R+I ++ A+KYLHD I+HRD+K EN LL Y+LD
Sbjct: 96 QLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPEN-LLYYSLD- 153
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
ED + ++DFGL K P + +T CG+ YV+PE+L PY + D
Sbjct: 154 -----EDSK-------IMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAV-D 200
Query: 449 AWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKN--ADTDHPAKEIVQ 506
W+ GVI Y LL PF + +I + ++++ D AK+ ++
Sbjct: 201 CWSIGVIAYILLCGYPPF------YDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIR 254
Query: 507 NTLVRKSE-RWNMDQLCNTPYI 527
+ + + E R+ +Q P+I
Sbjct: 255 HLMEKDPEKRFTCEQALQHPWI 276
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 95.1 bits (235), Expect = 2e-19
Identities = 66/230 (28%), Positives = 110/230 (47%), Gaps = 40/230 (17%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L+RE+ + + HP IVK + I + ++ LY ++ YC+ G+L++
Sbjct: 60 LEREVKIVKVIDHPHIVKSYEI-----MRVDNMLY------------IVSEYCSSGELYE 102
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
L K ++ + + +E + A+ YLH I+HRD+K EN+LL
Sbjct: 103 TLIEKGRVAENVARKWFSETASAVAYLHSQGIVHRDLKAENILLG--------------- 147
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+ +++ DFG T D++ T CGS Y +PE+LLG YDG +D W+ GV+ Y
Sbjct: 148 --KNSNIKIIDFGFSNFQTGDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYI 205
Query: 459 LLEDRLPFDPLPGQS-SRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQN 507
L+ PF P S ++ RS+ + + + W+ D K +V N
Sbjct: 206 LVAGGFPF---PSDSVNKLKRSVLSGLVKIPY-WVSVECADFIRKMLVLN 251
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 95.1 bits (235), Expect = 2e-19
Identities = 63/200 (31%), Positives = 102/200 (50%), Gaps = 36/200 (18%)
Query: 270 KELLSR-VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMI 328
KE LS V+ ++RE+ + + HP ++ L+ + + ++ LY ++
Sbjct: 80 KEKLSESVLQKVEREIAIMKLIEHPHVLHLYDVYE-----NKKYLY------------LL 122
Query: 329 MSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
+ + +GG+LFD L K ++ + + ++ A+ + H + I HRD+K EN+LL
Sbjct: 123 LEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLL----- 177
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
DE +N +++ADFG+ M T CGS Y PE++ G YDGR +
Sbjct: 178 -------DE-----RNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKA 225
Query: 448 DAWAFGVITYALLEDRLPFD 467
D W+ GVI YALL LPFD
Sbjct: 226 DVWSCGVILYALLVGALPFD 245
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 95.1 bits (235), Expect = 2e-19
Identities = 59/204 (28%), Positives = 101/204 (48%), Gaps = 38/204 (18%)
Query: 268 KYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
K K L ++ ++RE+ T+ + HP +V+L+ + +++ + +
Sbjct: 47 KEKVLKHKMAEQIRREIATMKLIKHPNVVQLYEV-----------------MASKTKIFI 89
Query: 328 IMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
I+ Y TGG+LFD + + ++ R +L A+ Y H + HRD+K EN+LL
Sbjct: 90 ILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPENLLLD--- 146
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYD 443
S ++++DFGL +++ D + T CG+ +YV+PE+L YD
Sbjct: 147 --------------SYGNLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYD 192
Query: 444 GRISDAWAFGVITYALLEDRLPFD 467
G +D W+ GV+ Y LL LPFD
Sbjct: 193 GATADMWSCGVVLYVLLAGYLPFD 216
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 94.7 bits (234), Expect = 3e-19
Identities = 57/189 (30%), Positives = 92/189 (48%), Gaps = 34/189 (17%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ + + H ++ LF + + ++ LY +++ Y GG+LFD
Sbjct: 161 IEREIVIMKLISHTNVMALFEVWE-----NKSELY------------LVLEYVDGGELFD 203
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
L SK K+P ++ + Y H I HRD+K EN+LL
Sbjct: 204 YLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDK-------------- 249
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+++ADFG+ P+++ T CGS Y SPEI++G PY G SD W+ G++ +A
Sbjct: 250 --KNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFA 307
Query: 459 LLEDRLPFD 467
LL LPF+
Sbjct: 308 LLTGHLPFN 316
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 94.7 bits (234), Expect = 3e-19
Identities = 58/199 (29%), Positives = 100/199 (50%), Gaps = 40/199 (20%)
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
++V +KRE++ + V HPC+V+L+ + L++ + +I+ Y TG
Sbjct: 49 KMVDQIKREISIMKLVRHPCVVRLYEV-----------------LASRTKIYIILEYITG 91
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LFD + ++ + +L + Y H + HRD+K EN+LL
Sbjct: 92 GELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLD---------- 141
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCT---TRCGSEDYVSPEILLGLPYDGRISDAW 450
S+ ++++DFGL P++ T T CG+ +YV+PE+L Y+G ++D W
Sbjct: 142 -------SQGNLKISDFGL--SALPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVADIW 192
Query: 451 AFGVITYALLEDRLPFDPL 469
+ GVI Y L+ LPFD +
Sbjct: 193 SCGVILYVLMAGYLPFDEM 211
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 94.4 bits (233), Expect = 4e-19
Identities = 82/288 (28%), Positives = 122/288 (41%), Gaps = 85/288 (29%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K IG GNF+ V L I + VA+K I + +P+S
Sbjct: 59 LKTIGKGNFAKVKLARHILTG---------REVAIKIIDKTQ-----LNPTS-------- 96
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ L RE+ + ++HP IVKLF + +T E LY +IM Y +G
Sbjct: 97 --LQKLFREVRIMKILNHPNIVKLFEVIET-----EKTLY------------LIMEYASG 137
Query: 335 GDLFDL------------------------ASKTKIPNWLLTRIITELSVAIKYLHDNFI 370
G++FD K ++ LL+ + T + A++Y H I
Sbjct: 138 GEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRI 197
Query: 371 IHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSED 430
+HRD+K EN+LL ++ +++ADFG + T T CGS
Sbjct: 198 VHRDLKAENLLLDADMN-----------------IKIADFGFSNEFTVGGKLDTFCGSPP 240
Query: 431 YVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTR 478
Y +PE+ G YDG D W+ GVI Y L+ LPFD GQ+ + R
Sbjct: 241 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---GQNLKELR 285
>Hs14042966 [T] KOG0583 Serine/threonine protein kinase
Length = 273
Score = 94.4 bits (233), Expect = 4e-19
Identities = 67/208 (32%), Positives = 100/208 (47%), Gaps = 39/208 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L REL+ L V HP IV +F + LY I+ DL
Sbjct: 57 LPRELSILRGVRHPHIVHVFEFIEVC----NGKLY-------------IVMEAAATDLLQ 99
Query: 340 LASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ +IP + +++ A++YLHD+ ++HRD+K ENVLL DE +
Sbjct: 100 AVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLS----------PDERR 149
Query: 399 FFSKNFVELADFGLCKKIT--PDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
V+L DFG ++ PD + TT CGS Y SPE+LLG+PYD + D W+ GV+
Sbjct: 150 ------VKLTDFGFGRQAHGYPD-LSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVL 202
Query: 457 YALLEDRLPFD--PLPGQSSRRTRSIAH 482
Y ++ +PFD + G R+ R + +
Sbjct: 203 YVMVTGCMPFDDSDIAGLPRRQKRGVLY 230
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 94.4 bits (233), Expect = 4e-19
Identities = 71/252 (28%), Positives = 120/252 (47%), Gaps = 59/252 (23%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS-RV 276
IGSG+F+ V+L + L VAVK I K+LLS +V
Sbjct: 16 IGSGSFAVVWLAKHRSSGLE---------VAVKEID----------------KKLLSPKV 50
Query: 277 VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGD 336
+L +E++ L ++ HP I++ + +T R +++ YC+GGD
Sbjct: 51 RDNLLKEISILSTIDHPNIIRFYEAIETG-----------------DRIFLVLEYCSGGD 93
Query: 337 LFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
L ++ K+P + + +L++ ++ L + IHRD+K +N+LL + + LLK
Sbjct: 94 LAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLS-SKEVTPLLK-- 150
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+ DFG + +TP+ M T CGS Y++PEI+ YD + +D W+ G I
Sbjct: 151 -----------IGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKYDAK-ADLWSAGAI 198
Query: 456 TYALLEDRLPFD 467
+ L+ + PFD
Sbjct: 199 LFQLVTGKPPFD 210
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 94.4 bits (233), Expect = 4e-19
Identities = 62/199 (31%), Positives = 99/199 (49%), Gaps = 35/199 (17%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
++L V+ ++RE+ + + HP ++ L + + ++ LY +I+
Sbjct: 52 EKLSESVLMKVEREIAIMKLIDHPHVLGLSDVYE-----NKKYLY------------LIL 94
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
+ +GG+LFD L K ++ + ++ A+ + H + I HRD+K EN+LL
Sbjct: 95 EHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLL------ 148
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
DE KN +++ADFG+ M T CGS Y PE++ G YDGR +D
Sbjct: 149 ------DE-----KNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKAD 197
Query: 449 AWAFGVITYALLEDRLPFD 467
W+ GVI YALL LPFD
Sbjct: 198 VWSCGVILYALLVGALPFD 216
>SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase
Length = 775
Score = 94.0 bits (232), Expect = 5e-19
Identities = 67/261 (25%), Positives = 119/261 (44%), Gaps = 44/261 (16%)
Query: 269 YKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMI 328
+ EL S + ++ EL L + HP +++L + +SA + ++
Sbjct: 44 WSELTSSQQARIEGELVLLRLIEHPNVLQLIDV-----------------ISAQEQLFVV 86
Query: 329 MSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
+ Y GG+LFD + K + + ++ ++Y H I HRD+K EN+ L
Sbjct: 87 VEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHICHRDLKPENLYLD---- 142
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
+ +++ +FG+ P ++ T CGS Y SPEI++G YDG S
Sbjct: 143 -------------AHGSIKIGEFGMASIQQPGKLLQTSCGSPHYASPEIIMGRSYDGCAS 189
Query: 448 DAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQN 507
D W+ G+I +ALL +LPFD RS+ ++ C ++ ++ A+ ++
Sbjct: 190 DIWSCGIIFFALLTGKLPFD------DDNIRSLLLKV--CQGQFEMPSNISPQAQHLLYR 241
Query: 508 TL-VRKSERWNMDQLCNTPYI 527
L V S R M+Q+ P++
Sbjct: 242 MLDVDSSTRITMEQIREHPFL 262
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 93.6 bits (231), Expect = 7e-19
Identities = 70/253 (27%), Positives = 113/253 (43%), Gaps = 44/253 (17%)
Query: 277 VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGD 336
+ L RE+ + ++HP IVKLF + +T E LY ++M Y + G+
Sbjct: 100 LQKLFREVRIMKGLNHPNIVKLFEVIET-----EKTLY------------LVMEYASAGE 142
Query: 337 LFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+FD L S ++ ++ A+ Y H I+HRD+K EN+LL +
Sbjct: 143 VFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN-------- 194
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+++ADFG + T T CGS Y +PE+ G YDG D W+ GVI
Sbjct: 195 ---------IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 245
Query: 456 TYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLV-RKSE 514
Y L+ LPFD + + R+ R ++ TD + I++ LV ++
Sbjct: 246 LYTLVSGSLPFD------GHNLKELRERVLRGKYRVPFYMSTD--CESILRRFLVLNPAK 297
Query: 515 RWNMDQLCNTPYI 527
R ++Q+ +I
Sbjct: 298 RCTLEQIMKDKWI 310
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 92.0 bits (227), Expect = 2e-18
Identities = 67/258 (25%), Positives = 118/258 (44%), Gaps = 47/258 (18%)
Query: 210 FQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKY 269
F++SK +G G F+ VY +D ++ +K +A K+I K
Sbjct: 7 FEYSKRDLLGHGAFAIVYRGRYVD---RTDVPVAIKAIAKKNIS--------------KS 49
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
K LL++ + LK L S+ H +V L +T ++M
Sbjct: 50 KNLLTKEIKILKE----LSSLKHENLVGLLKCTETP-----------------THVYLVM 88
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
+C GGDL D L KT + + + +++ A++ ++ I+HRD+K +N+LL
Sbjct: 89 EFCNGGDLADYLQQKTTLNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNN--- 145
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
++ F+ ++LADFG + + M T CGS Y++PE+++ + YD + +D
Sbjct: 146 ----SRTQNPHFTDIVIKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMSMQYDAK-AD 200
Query: 449 AWAFGVITYALLEDRLPF 466
W+ G I + L + PF
Sbjct: 201 LWSIGTILFQCLTGKAPF 218
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 91.3 bits (225), Expect = 3e-18
Identities = 52/189 (27%), Positives = 91/189 (47%), Gaps = 35/189 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ + S++HP I+ + + + + + ++M Y + GDL+D
Sbjct: 97 IRREIEIMSSLNHPHIIAIHEVFENS-----------------SKIVIVMEYASRGDLYD 139
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
++ + ++ ++ A+ Y H N ++HRD+KLEN+LL
Sbjct: 140 YISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLD--------------- 184
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+ +++ADFGL + T CGS Y SPEI+ G PY G D+W+ GV+ Y
Sbjct: 185 --ANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYI 242
Query: 459 LLEDRLPFD 467
L+ +PFD
Sbjct: 243 LVHGTMPFD 251
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 91.3 bits (225), Expect = 3e-18
Identities = 74/279 (26%), Positives = 129/279 (45%), Gaps = 47/279 (16%)
Query: 268 KYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
K K L S +++ +KRE++ L V HP IV+LF + T + +Y
Sbjct: 61 KEKVLKSGLIAHIKREISILRRVRHPNIVQLFEVMAT-----KSKIY------------F 103
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
+M Y GG+LF+ +K ++ + + +L A+ + H + HRD+K EN+LL
Sbjct: 104 VMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLL----- 158
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCK---KITPDEMCTTRCGSEDYVSPEILLGLPYDG 444
DE+ ++++DFGL +I D + T CG+ YV+PE+L YDG
Sbjct: 159 -------DEN-----GNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDG 206
Query: 445 RISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEI 504
D W+ GVI + L+ LPF R ++ +I R D++ + + + +
Sbjct: 207 AKVDIWSCGVILFVLMAGFLPF------HDRNVMAMYKKIYRGDFRCPRWFPVE-INRLL 259
Query: 505 VQNTLVRKSERWNMDQLCNTPYIRNIIDKLQFL---DHQ 540
++ + R+ M + T + + ++F DHQ
Sbjct: 260 IRMLETKPERRFTMPDIMETSWFKKGFKHIKFYVEDDHQ 298
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 91.3 bits (225), Expect = 3e-18
Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 35/189 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ L HP I++L+ + +T TD + ++M Y G+LFD
Sbjct: 64 VRREIKILRLFMHPHIIRLYEVIETP--TDIY---------------LVMEYVNSGELFD 106
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ K ++ ++ ++Y H N ++HRD+K EN+LL
Sbjct: 107 YIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD--------------- 151
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
SK V++ADFGL + T CGS +Y +PE++ G Y G D W+ GVI YA
Sbjct: 152 --SKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYA 209
Query: 459 LLEDRLPFD 467
LL LPFD
Sbjct: 210 LLCGTLPFD 218
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 91.3 bits (225), Expect = 3e-18
Identities = 57/202 (28%), Positives = 95/202 (46%), Gaps = 45/202 (22%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
++ ++RE+ + + HP +V+L R ++ + +M Y GG
Sbjct: 57 MMEQIEREIAVMRLLRHPNVVEL-----------------REVMATKKKIFFVMEYVNGG 99
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LF++ + K+P L + +L A+ + H + HRDIK EN+LL D
Sbjct: 100 ELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGD------- 152
Query: 395 DESQFFSKNFVELADFGLCKKITP----------DEMCTTRCGSEDYVSPEILLGLPYDG 444
+++ DFGL + P D++ TRCG+ YV+PE+L YDG
Sbjct: 153 ----------LKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLRNKGYDG 202
Query: 445 RISDAWAFGVITYALLEDRLPF 466
++D W+ G++ YALL LPF
Sbjct: 203 AMADIWSCGIVLYALLAGFLPF 224
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 90.9 bits (224), Expect = 4e-18
Identities = 75/256 (29%), Positives = 113/256 (43%), Gaps = 24/256 (9%)
Query: 281 KRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD- 339
+ E L+ V HP IV L + Y +++ G+LF+
Sbjct: 246 REETNILMRVQHPNIVNLLDSFVEPISKSQIQKY------------LVLEKIDDGELFER 293
Query: 340 LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL----DDMMLLKED 395
+ KT + + +L +KYLH+ IIHRDIK EN+LL T + L D
Sbjct: 294 IVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWD 353
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
E + + V++ADFGL K + T CG+ YV+PE+L Y ++ D W+ GVI
Sbjct: 354 EDEIDIQ--VKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKV-DLWSAGVI 410
Query: 456 TYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLV-RKSE 514
Y L PF G S + + + + A W K D ++ N LV E
Sbjct: 411 LYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDK---IDDSVLHLISNLLVLNPDE 467
Query: 515 RWNMDQLCNTPYIRNI 530
R+N+D+ N P+ +I
Sbjct: 468 RYNIDEALNHPWFNDI 483
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 90.9 bits (224), Expect = 4e-18
Identities = 61/189 (32%), Positives = 94/189 (49%), Gaps = 36/189 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE++ L + HP I+KL+ + T TD M++ Y GG+LFD
Sbjct: 79 VEREISYLKLLRHPHIIKLYDVITTP--TD---------------IVMVIEYA-GGELFD 120
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ K ++ R ++ AI+Y H + I+HRD+K EN+LL L+
Sbjct: 121 YIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLN----------- 169
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
V++ADFGL +T T CGS +Y +PE++ G Y G D W+ G++ Y
Sbjct: 170 ------VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYV 223
Query: 459 LLEDRLPFD 467
+L RLPFD
Sbjct: 224 MLVGRLPFD 232
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 90.9 bits (224), Expect = 4e-18
Identities = 59/192 (30%), Positives = 90/192 (46%), Gaps = 37/192 (19%)
Query: 279 SLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF 338
+++RE+ + + HP IV+LF + L+ + +M + GG+LF
Sbjct: 66 NIQREIAIMHRLRHPSIVRLFEV-----------------LATKSKIFFVMEFAKGGELF 108
Query: 339 DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
SK + L R +L A+ Y H I HRD+K EN+LL LD
Sbjct: 109 AKVSKGRFCEDLSRRYFQQLISAVGYCHSRGIFHRDLKPENLLLDEKLD----------- 157
Query: 399 FFSKNFVELADFGLCK---KITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
++++DFGL +I PD + T CG+ YV+PE+L YDG D W+ G+I
Sbjct: 158 ------LKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDGAKIDIWSCGII 211
Query: 456 TYALLEDRLPFD 467
+ L LPF+
Sbjct: 212 LFVLNAGYLPFN 223
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 90.9 bits (224), Expect = 4e-18
Identities = 82/330 (24%), Positives = 141/330 (41%), Gaps = 71/330 (21%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K +GSG F+ VY E +L + VA+K ++ K L
Sbjct: 32 KLLGSGAFAKVYQAE--------DLQNGGESVAIKVVQK---------------KRLKDG 68
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ + +KRE++ + + HP IV L + L+ + +M GG
Sbjct: 69 LTAHVKREISVMRRLRHPHIVLLSEV-----------------LATKTKIYFVMELAKGG 111
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LF + + L + +L A++Y H + HRD+K EN+LL D
Sbjct: 112 ELFSRVTSNRFTESLSRKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRD-------- 163
Query: 396 ESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++++DFGL ++I PD M T CG+ YV+PE+LL YDG +D W+
Sbjct: 164 ---------LKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWSC 214
Query: 453 GVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVR 511
GV+ + L LPF DP R+ +++ DW T +++++ L
Sbjct: 215 GVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLP--DW-------TSSDLRKLLRRLLEP 265
Query: 512 KSE-RWNMDQLCNTPYIRNIIDKLQFLDHQ 540
E R ++++ P+ + +D + + Q
Sbjct: 266 NPELRITVEEILKDPWFNHGVDPSEIIGIQ 295
>7300413 [T] KOG0583 Serine/threonine protein kinase
Length = 302
Score = 90.9 bits (224), Expect = 4e-18
Identities = 69/256 (26%), Positives = 116/256 (44%), Gaps = 46/256 (17%)
Query: 282 RELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLA 341
REL L + H I+++ +I L P+ + M Y GDL
Sbjct: 78 RELEILTKIDHSNIIQIHSI-----------------LQRGPKIFIFMRYAENGDLLSHI 120
Query: 342 SKTKIPNWLLTRI-ITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFF 400
++ + ++I ++S A+KYLH+ I HRD+K EN+LL L+
Sbjct: 121 KRSGPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKRLN------------- 167
Query: 401 SKNFVELADFGLCKKITPDE----MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
++LADFG + D T CGS Y +PE++ G PYD +++DAW+ GVI
Sbjct: 168 ----IKLADFGFARYCRDDNGREMKSETYCGSAAYAAPEVVCGRPYDPKLADAWSLGVIL 223
Query: 457 YALLEDRLPFDPLPGQSSRRTRSIA-HRIARCDWKWLKNADTDHPAKEIVQNTLVRKSE- 514
+ ++ ++PFD S T+ + R + ++ AK V L ++
Sbjct: 224 FIMMNAKMPFD-----DSNLTKLLEDQRNRKFAFRRKLQETISAQAKATVSVLLEPEAHA 278
Query: 515 RWNMDQLCNTPYIRNI 530
RWN+ ++ N ++R +
Sbjct: 279 RWNLREILNCAWLRTV 294
>Hs4506071 [T] KOG0695 Serine/threonine protein kinase
Length = 587
Score = 90.5 bits (223), Expect = 6e-18
Identities = 52/146 (35%), Positives = 81/146 (54%), Gaps = 20/146 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R ++ Y GGDL F + + K+P E+S+A+ YLH+ II+RD+KL+NVLL
Sbjct: 318 RLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLL 377
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
S+ ++L D+G+CK+ + P + +T CG+ +Y++PEIL G
Sbjct: 378 D-----------------SEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGED 420
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G D WA GV+ + ++ R PFD
Sbjct: 421 Y-GFSVDWWALGVLMFEMMAGRSPFD 445
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 90.5 bits (223), Expect = 6e-18
Identities = 70/253 (27%), Positives = 113/253 (43%), Gaps = 59/253 (23%)
Query: 216 KEIGSGNFSTVYL-YECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+ IG GNF+ V L Y+ + YVAVK I K +
Sbjct: 16 RTIGEGNFAKVKLGYDTTNGT----------YVAVKIID--------------KALVIQK 51
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ S +KRE+ T+ ++HP IV++ H + G + + ++M Y +G
Sbjct: 52 GLESQVKREIRTMKLLNHPNIVQI------------HEVIGTKT-----KICIVMEYVSG 94
Query: 335 GDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
G L D + K+ ++ +L A+ Y H+ + HRD+K +N+LL
Sbjct: 95 GQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLD----------- 143
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
SK ++++DFGL +M +T CGS Y++PE+++ Y G D W+ GV
Sbjct: 144 ------SKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYSGAAVDVWSCGV 197
Query: 455 ITYALLEDRLPFD 467
I + LL PFD
Sbjct: 198 ILFELLAGYPPFD 210
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 90.5 bits (223), Expect = 6e-18
Identities = 71/254 (27%), Positives = 114/254 (43%), Gaps = 60/254 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K +G G F+ VYL + N + VA+K I K K L
Sbjct: 30 KLLGHGTFAKVYLARNVKTN---------ESVAIKVID--------------KEKVLKGG 66
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+++ +KRE++ L V HP IV+LF + ++ + +M Y GG
Sbjct: 67 LIAHIKREISILRRVRHPNIVQLFEV-----------------MATKAKIYFVMEYVRGG 109
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LF+ +K ++ + + +L A+ + H + HRD+K EN+LL D
Sbjct: 110 ELFNKVAKGRLKEEVARKYFQQLISAVTFCHARGVYHRDLKPENLLL------------D 157
Query: 396 ESQFFSKNFVELADFGLCK---KITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
E+ ++++DFGL +I D + T CG+ YV+PE+L YD D W+
Sbjct: 158 EN-----GNLKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDAAKVDIWSC 212
Query: 453 GVITYALLEDRLPF 466
GVI + L+ LPF
Sbjct: 213 GVILFVLMAGYLPF 226
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 90.1 bits (222), Expect = 8e-18
Identities = 54/147 (36%), Positives = 78/147 (52%), Gaps = 18/147 (12%)
Query: 323 PRCDMIM-SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENV 380
P C I+ Y GG L + + ++ K+ L +L A+ YLH NFI+HRD+K+ENV
Sbjct: 122 PACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFIVHRDLKIENV 181
Query: 381 LLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGL 440
LL +D Q V+L DFGL + D++ T CGS + +PE+L
Sbjct: 182 LLT----------QDSRQ------VKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAK 225
Query: 441 PYDGRISDAWAFGVITYALLEDRLPFD 467
PY G D W+ GV+ Y ++ R+PFD
Sbjct: 226 PYIGPEVDVWSLGVVIYVMVCGRVPFD 252
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 90.1 bits (222), Expect = 8e-18
Identities = 71/271 (26%), Positives = 120/271 (44%), Gaps = 64/271 (23%)
Query: 201 MANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLM 260
M N P+ ++ ++ + +G G F+ VY N + VA+K I + + +
Sbjct: 1 MENKPSVLTERYEVGRLLGQGTFAKVYFGRSNHTN---------ESVAIKMIDKDKVMRV 51
Query: 261 SSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLS 320
S +KRE++ + HP +V+L+ + ++
Sbjct: 52 GLS--------------QQIKREISVMRIAKHPNVVELYEV-----------------MA 80
Query: 321 ALPRCDMIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENV 380
R ++ YC GG+LF+ +K K+ + + +L A+ + H + HRDIK EN+
Sbjct: 81 TKSRIYFVIEYCKGGELFNKVAKGKLKEDVAWKYFYQLISAVDFCHSRGVYHRDIKPENL 140
Query: 381 LLKYTLDDMMLLKEDESQFFSKNFVELADFGL-----CKKITPDEMCTTRCGSEDYVSPE 435
L LDD LK ++DFGL CK+ D + T CG+ YV+PE
Sbjct: 141 L----LDDNDNLK-------------VSDFGLSALADCKR--QDGLLHTTCGTPAYVAPE 181
Query: 436 ILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
++ Y+G +D W+ GV+ + LL LPF
Sbjct: 182 VINRKGYEGTKADIWSCGVVLFVLLAGYLPF 212
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 90.1 bits (222), Expect = 8e-18
Identities = 53/202 (26%), Positives = 102/202 (50%), Gaps = 36/202 (17%)
Query: 268 KYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
K K L +++++ +KRE++T+ + HP ++++F + +++ +
Sbjct: 64 KEKVLKNKMIAQIKREISTMKLIKHPNVIRMFEV-----------------MASKTKIYF 106
Query: 328 IMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
++ + TGG+LFD ++S ++ + +L A+ Y H + HRD+K EN+LL
Sbjct: 107 VLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD--- 163
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCK-KITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+ ++++DFGL D + T CG+ +YV+PE++ YDG
Sbjct: 164 --------------ANGALKVSDFGLSALPQQEDGLLHTTCGTPNYVAPEVINNKGYDGA 209
Query: 446 ISDAWAFGVITYALLEDRLPFD 467
+D W+ GVI + L+ LPF+
Sbjct: 210 KADLWSCGVILFVLMAGYLPFE 231
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 89.7 bits (221), Expect = 1e-17
Identities = 58/189 (30%), Positives = 92/189 (47%), Gaps = 36/189 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE++ L + HP I+KL+ + + + M++ Y G +LFD
Sbjct: 100 IEREISYLRLLRHPHIIKLYDV-----------------IKSKDEIIMVIEYA-GNELFD 141
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ + K+ R ++ A++Y H + I+HRD+K EN+LL L+
Sbjct: 142 YIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN----------- 190
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
V++ADFGL +T T CGS +Y +PE++ G Y G D W+ GVI Y
Sbjct: 191 ------VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYV 244
Query: 459 LLEDRLPFD 467
+L RLPFD
Sbjct: 245 MLCRRLPFD 253
>SPAC890.03 [T] KOG0583 Serine/threonine protein kinase
Length = 672
Score = 89.7 bits (221), Expect = 1e-17
Identities = 72/257 (28%), Positives = 110/257 (42%), Gaps = 74/257 (28%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G G+F VYL + N + L + A+ +L+R +
Sbjct: 37 VGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAI----------------------ILAREI 74
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
+R L HP I +L+ + + E +Y + M YC G+L
Sbjct: 75 HHHRRLL-------HPNITRLYEV-----VCTEDRIY------------LAMEYCPNGEL 110
Query: 338 FD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDE 396
+D +A + ++ RI+ +L AI+YLH +HRD+KLEN+ L +
Sbjct: 111 YDWVAREKRLDEKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYN--------- 161
Query: 397 SQFFSKNFVELADFGLCKKITPDEMCT------TRCGSEDYVSPEILLGLPYDGRISDAW 450
V+L DFG + D C+ TRCG+ Y +PE++ G Y G D W
Sbjct: 162 --------VKLGDFGFSR----DSDCSRRTFMNTRCGTVAYCAPELVQGHKYIGECVDIW 209
Query: 451 AFGVITYALLEDRLPFD 467
+ G+I YALL RLPFD
Sbjct: 210 SLGIIMYALLIGRLPFD 226
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 89.7 bits (221), Expect = 1e-17
Identities = 68/257 (26%), Positives = 117/257 (45%), Gaps = 46/257 (17%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
++ +KRE++ + V HP IV+L + ++ + +M + GG
Sbjct: 54 MMEQIKREISIMKLVRHPNIVEL-----------------KEVMATKTKIFFVMEFVKGG 96
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LF SK K+ R +L A+ Y H + HRD+K EN+LL D
Sbjct: 97 ELFCKISKGKLHEDAARRYFQQLISAVDYCHSRGVSHRDLKPENLLLDENGD-------- 148
Query: 396 ESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++++DFGL ++I D + T+CG+ YV+PE+L YDG +D W+
Sbjct: 149 ---------LKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYDGAKADIWSC 199
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTL-VR 511
GV+ Y LL LPF ++ +I R D+++ + A+ ++ L V
Sbjct: 200 GVVLYVLLAGCLPF------QDENLMNMYRKIFRADFEFPPWFSPE--ARRLISKLLVVD 251
Query: 512 KSERWNMDQLCNTPYIR 528
R ++ + TP++R
Sbjct: 252 PDRRISIPAIMRTPWLR 268
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 89.7 bits (221), Expect = 1e-17
Identities = 53/197 (26%), Positives = 98/197 (48%), Gaps = 38/197 (19%)
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
++V LKRE++T+ + HP +V++ + +++ + +++ G
Sbjct: 59 KMVEQLKREISTMKLIKHPNVVEIIEV-----------------MASKTKIYIVLELVNG 101
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LFD +A + ++ R +L A+ Y H + HRD+K EN++L
Sbjct: 102 GELFDKIAQQGRLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILD---------- 151
Query: 394 EDESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAW 450
+ ++++DFGL +++ D + T CG+ +YV+PE+L YDG +D W
Sbjct: 152 -------ANGVLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSDKGYDGAAADVW 204
Query: 451 AFGVITYALLEDRLPFD 467
+ GVI + L+ LPFD
Sbjct: 205 SCGVILFVLMAGYLPFD 221
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 89.7 bits (221), Expect = 1e-17
Identities = 70/255 (27%), Positives = 115/255 (44%), Gaps = 46/255 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L +E+ + V HP +V+L+ + DT + LY +++ GGDL+D
Sbjct: 64 LFQEVRCMKLVQHPNVVRLYEVIDT-----QTKLY------------LVLELGDGGDLYD 106
Query: 340 LASK--TKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
K + + L + ++ AI Y H ++HRD+K ENV+
Sbjct: 107 YIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPENVV---------------- 150
Query: 398 QFFSK-NFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
FF K V+L DFG K P + T CGS Y +PEILLG YD D W+ GVI
Sbjct: 151 -FFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVIL 209
Query: 457 YALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVR-KSER 515
Y L+ + PF+ I C + + TD ++++ + LVR +R
Sbjct: 210 YMLVCGQAPFE------KANDSETLTMIMDCKYTVPSHVSTD--CRDLIASMLVRDPKKR 261
Query: 516 WNMDQLCNTPYIRNI 530
++++ ++ +++ I
Sbjct: 262 ATVEEIASSAWLKPI 276
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 89.4 bits (220), Expect = 1e-17
Identities = 61/189 (32%), Positives = 89/189 (46%), Gaps = 35/189 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L +E+ + V HP IV+L+ + DT + LY +I+ GGD+FD
Sbjct: 60 LFQEVRCMKLVQHPNIVRLYEVIDT-----QTKLY------------LILELGDGGDMFD 102
Query: 340 LASKTK--IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
K + + L + ++ AI Y H ++HRD+K ENV+
Sbjct: 103 YIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVF--------------- 147
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
F + V+L DFG K P + TT CGS Y +PEILLG YD D W+ GVI +
Sbjct: 148 -FEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILF 206
Query: 458 ALLEDRLPF 466
L+ ++ PF
Sbjct: 207 MLVCEQPPF 215
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 89.4 bits (220), Expect = 1e-17
Identities = 70/253 (27%), Positives = 115/253 (44%), Gaps = 59/253 (23%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K +G G+F V+L E N ++ A+K++K L+ + K +LS
Sbjct: 384 KMLGKGSFGKVFLAEFKKTN---------QFFAIKALKKDVVLMDDDVECTMVEKRVLS- 433
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
++ HP + +F TF T E+ + +M Y GG
Sbjct: 434 ------------LAWEHPFLTHMFC----TFQTKENLFF-------------VMEYLNGG 464
Query: 336 DL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
DL + + S K T E+ + +++LH I++RD+KL+N+LL
Sbjct: 465 DLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLD----------- 513
Query: 395 DESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ADFG+CK+ + D T CG+ DY++PEILLG Y+ + D W+FG
Sbjct: 514 ------KDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSV-DWWSFG 566
Query: 454 VITYALLEDRLPF 466
V+ Y +L + PF
Sbjct: 567 VLLYEMLIGQSPF 579
>At5g35410 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 89.4 bits (220), Expect = 1e-17
Identities = 60/204 (29%), Positives = 101/204 (49%), Gaps = 38/204 (18%)
Query: 272 LLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSY 331
L +R+V +KRE++ + V HP IV+L+ + L++ + +++ +
Sbjct: 48 LKNRMVDQIKREISIMKIVRHPNIVRLYEV-----------------LASPSKIYIVLEF 90
Query: 332 CTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMM 390
TGG+LFD + K ++ + +L A+ + H + HRD+K EN+LL
Sbjct: 91 VTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLD------- 143
Query: 391 LLKEDESQFFSKNFVELADFGLCKKITPD-EMCTTRCGSEDYVSPEILLGLPYDGRISDA 449
+ ++++DFGL E+ T CG+ +YV+PE+L G YDG +D
Sbjct: 144 ----------TNGNLKVSDFGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYDGSAADI 193
Query: 450 WAFGVITYALLEDRLPFD--PLPG 471
W+ GVI + +L LPF LPG
Sbjct: 194 WSCGVILFVILAGYLPFSETDLPG 217
>At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 225
Score = 89.4 bits (220), Expect = 1e-17
Identities = 57/189 (30%), Positives = 93/189 (49%), Gaps = 35/189 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAIN-DTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF 338
L EL L SV HP I++L ++ D F+ M++ YC GG L
Sbjct: 49 LNNELEFLSSVDHPNIIRLLHVSQDDDFLV------------------MVLEYCDGGTLS 90
Query: 339 DLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ ++ + R + ++ ++ +HDN IIHRD+K EN+L+ + DD++L
Sbjct: 91 SYIQRYGRVEEDIAKRFMKQIGAGLEIIHDNHIIHRDLKPENILIDGSGDDLVL------ 144
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
++ADF L +K+ P + T CGS Y++PE+L Y+ + +D W+ G I +
Sbjct: 145 --------KIADFSLARKLHPGKYLETVCGSPFYMAPEVLQFQRYNEK-ADMWSVGAILF 195
Query: 458 ALLEDRLPF 466
LL PF
Sbjct: 196 ELLHGYPPF 204
>7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 835
Score = 88.6 bits (218), Expect = 2e-17
Identities = 71/258 (27%), Positives = 116/258 (44%), Gaps = 48/258 (18%)
Query: 210 FQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKY 269
+++S +G G F+ VY ++ VA+K I +L K
Sbjct: 7 YEYSSKDMLGHGAFAVVYKGRHRKKHMP---------VAIKCITKKGQL---------KT 48
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
+ LL + + LK ELT L HH +V L ++ ++M
Sbjct: 49 QNLLGKEIKILK-ELTEL---HHENVVALLDCKESQDCVS-----------------LVM 87
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
YC GGDL D L+ K + + + +L+ A+K L+ I+HRD+K +N+LL +
Sbjct: 88 EYCNGGDLADYLSVKGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGK 147
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
+ SK +++ADFG + + M T CGS Y++PE+++ L YD + +D
Sbjct: 148 TLPAP-------SKITLKIADFGFARFLNEGAMAATLCGSPMYMAPEVIMSLQYDSK-AD 199
Query: 449 AWAFGVITYALLEDRLPF 466
W+ G I Y L + PF
Sbjct: 200 LWSLGTIVYQCLTGKAPF 217
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 88.6 bits (218), Expect = 2e-17
Identities = 64/242 (26%), Positives = 113/242 (46%), Gaps = 44/242 (18%)
Query: 282 RELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLA 341
RE+ + + HP I+KL+ + +T ++ +Y ++ Y + G++FD
Sbjct: 187 REVEIMKRLKHPHIIKLYQVMET-----KNMIY------------IVSEYASQGEIFDYI 229
Query: 342 SKTKIPNWLLTRI-ITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFF 400
+K + R ++ A++Y H I+HRD+K EN+LL ++
Sbjct: 230 AKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMN------------- 276
Query: 401 SKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALL 460
+++ADFG P E+ T CGS Y +PE+ G Y G D W+ GV+ Y L+
Sbjct: 277 ----IKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLV 332
Query: 461 EDRLPFDPLPGQSSR-RTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRKSERWNMD 519
LPFD QS R R S RI + +++ +H + ++ ++ + R+ +D
Sbjct: 333 CGALPFDGSTLQSLRDRVLSGRFRI-----PFFMSSECEHLIRRML---VLEPTRRYTID 384
Query: 520 QL 521
Q+
Sbjct: 385 QI 386
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 88.2 bits (217), Expect = 3e-17
Identities = 70/253 (27%), Positives = 117/253 (45%), Gaps = 61/253 (24%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
++ +G+G+F V+L I N ++ A+K++K K+ +
Sbjct: 91 LRTLGTGSFGRVHL---------IRSNHNGRFYALKTLK--------------KHTIVKL 127
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ V E L V HP I++++ TF D ++ M+M Y G
Sbjct: 128 KQVEHTNDERRMLSIVSHPFIIRMWG----TF-QDSQQVF------------MVMDYIEG 170
Query: 335 GDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LF L K+ + PN + E+ +A++YLH II+RD+K EN+LL
Sbjct: 171 GELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD---------- 220
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ DFG K + PD + T CG+ DY++PE++ PY+ + D W+FG
Sbjct: 221 -------KNGHIKITDFGFAKYV-PD-VTYTLCGTPDYIAPEVVSTKPYNKSV-DWWSFG 270
Query: 454 VITYALLEDRLPF 466
V+ Y +L PF
Sbjct: 271 VLIYEMLAGYTPF 283
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 88.2 bits (217), Expect = 3e-17
Identities = 65/231 (28%), Positives = 106/231 (45%), Gaps = 33/231 (14%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCD-MI 328
K+ LS+ L +E+ L + H IV L+ + + LP ++
Sbjct: 43 KKNLSKSQILLGKEIKILKELQHENIVALYDVQE------------------LPNSVFLV 84
Query: 329 MSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
M YC GGDL D L +K + + + +++ A++ LH IIHRD+K +N+LL Y
Sbjct: 85 MEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYA-- 142
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
S +++ADFG + + + M T CGS Y++PE+++ YD + +
Sbjct: 143 ------NRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAK-A 195
Query: 448 DAWAFGVITYALLEDRLPFDPLPGQSSR----RTRSIAHRIARCDWKWLKN 494
D W+ G + Y L + PF Q R + RS+ I R +L N
Sbjct: 196 DLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLAN 246
>Hs14916455 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 88.2 bits (217), Expect = 3e-17
Identities = 75/249 (30%), Positives = 115/249 (46%), Gaps = 40/249 (16%)
Query: 283 ELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LA 341
EL+ L V H IV+L I +T E +Y M+M TGG+LFD L
Sbjct: 108 ELSVLRRVSHRYIVQLMEIFET-----EDQVY------------MVMELATGGELFDRLI 150
Query: 342 SKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFS 401
++ RI+ ++ I+YLH I HR++K EN+L + ++ +L
Sbjct: 151 AQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYYHPGEESKIL--------- 201
Query: 402 KNFVELADFGLCK--KITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYAL 459
+ DFGL K + D T CG+ +Y++PE+LL PY + D WA GVITYAL
Sbjct: 202 -----ITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAV-DMWALGVITYAL 255
Query: 460 LEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRKS-ERWNM 518
L LPFD Q+ + + + W H AK+ + L+ ++ R +
Sbjct: 256 LSGFLPFDD-ESQTRLYRKILKGKYNYTGEPW---PSISHLAKDFIDKLLILEAGHRMSA 311
Query: 519 DQLCNTPYI 527
Q + P++
Sbjct: 312 GQALDHPWV 320
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 88.2 bits (217), Expect = 3e-17
Identities = 56/189 (29%), Positives = 89/189 (46%), Gaps = 35/189 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ L HP I++ + + +TT +Y ++M Y G+LFD
Sbjct: 65 VRREIKILRLFMHPHIIRQYEVIETT-----SDIY------------VVMEYVKSGELFD 107
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ K ++ ++ ++Y H N ++HRD+K EN+LL
Sbjct: 108 YIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD--------------- 152
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
S+ +++ADFGL + T CGS +Y +PE++ G Y G D W+ GVI YA
Sbjct: 153 --SRCNIKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYA 210
Query: 459 LLEDRLPFD 467
LL LPFD
Sbjct: 211 LLCGTLPFD 219
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 87.8 bits (216), Expect = 4e-17
Identities = 85/329 (25%), Positives = 150/329 (44%), Gaps = 50/329 (15%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+ +IG G FS V+ + + N + +K + K I L + K++L+
Sbjct: 124 LNKIGEGAFSRVF--KAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGSSRKKVLN 181
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
V + L+S ++P K A ++ + Y ++ TG
Sbjct: 182 EVA------IHKLVSKNNPHCTKFIAFQESA-----NYYY------------LVTELVTG 218
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLK----YTLDDM 389
G++FD + T L +IT++++AIK++H I+HRD+K EN+L + Y LD
Sbjct: 219 GEIFDRIVQLTCFSEDLARHVITQVAIAIKHMHYMGIVHRDVKPENLLFEPIPFYGLDGD 278
Query: 390 MLLKEDESQF----FSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
M KEDE V+L DFGL KK+ + T CG+ +YV+ E+ Y +
Sbjct: 279 M-QKEDEFTLGVGGGGIGLVKLMDFGLAKKLR-NNTAKTPCGTIEYVASEVFTSKRYSMK 336
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWK----WLKNADTDHPA 501
+ D W+ G + + LL PF + +++ +I+R D++ W N + A
Sbjct: 337 V-DMWSIGCVLFTLLCGYPPF------YEKNEKTLLKKISRGDYEFLAPWWDNISSG--A 387
Query: 502 KEIVQNTL-VRKSERWNMDQLCNTPYIRN 529
K V + L V ++R+++D N P++ +
Sbjct: 388 KNAVTHLLEVDPNKRYDIDDFLNDPWLNS 416
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 87.8 bits (216), Expect = 4e-17
Identities = 57/174 (32%), Positives = 88/174 (49%), Gaps = 29/174 (16%)
Query: 298 LFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF---DLASKTKIPNWLLTRI 354
L ++ F+T H + + R +M Y GGDL K K P +
Sbjct: 391 LALLDKPPFLTQLHSCF-----QTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVF--Y 443
Query: 355 ITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCK 414
E+S+ + +LH II+RD+KL+NV+L S+ +++ADFG+CK
Sbjct: 444 AAEISIGLFFLHKRGIIYRDLKLDNVMLD-----------------SEGHIKIADFGMCK 486
Query: 415 KITPDEMCT-TRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFD 467
+ D + T T CG+ DY++PEI+ PY G+ D WA+GV+ Y +L + PFD
Sbjct: 487 EHMMDGVTTRTFCGTPDYIAPEIIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFD 539
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 87.8 bits (216), Expect = 4e-17
Identities = 58/192 (30%), Positives = 92/192 (47%), Gaps = 35/192 (18%)
Query: 277 VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGD 336
V+ + E+ L + HP I +LF R +S ++M +GG+
Sbjct: 66 VNKTRNEIDNLQKLTHPHITRLF-----------------RVISTPSDIFLVMELVSGGE 108
Query: 337 LFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
LF + K +P R ++ + Y H++ I+HRD+K EN+LL
Sbjct: 109 LFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDA----------- 157
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+KN +++ADFGL +T ++ +T CGS +Y +PE++ Y G D W+ GVI
Sbjct: 158 -----NKN-IKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVI 211
Query: 456 TYALLEDRLPFD 467
YA+L LPFD
Sbjct: 212 LYAMLCGTLPFD 223
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 87.8 bits (216), Expect = 4e-17
Identities = 57/194 (29%), Positives = 90/194 (46%), Gaps = 37/194 (19%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
++ +KRE++ + V HP +V L + +++ + M Y GG
Sbjct: 53 LIDQIKREISVMRLVRHPHVVFLHEV-----------------MASKTKIYFAMEYVKGG 95
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LFD SK K+ + + +L AI Y H + HRD+K EN+LL D
Sbjct: 96 ELFDKVSKGKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGD-------- 147
Query: 396 ESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++++DFGL + D + T CG+ YV+PE++ YDG +D W+
Sbjct: 148 ---------LKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWSC 198
Query: 453 GVITYALLEDRLPF 466
GV+ Y LL LPF
Sbjct: 199 GVVLYVLLAGFLPF 212
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 87.8 bits (216), Expect = 4e-17
Identities = 58/189 (30%), Positives = 91/189 (47%), Gaps = 36/189 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ L + HP I++ + + +T + +Y ++M Y G+LFD
Sbjct: 64 VQREIKILRFLMHPHIIRQYEVIETP-----NDIY------------VVMEYVKSGELFD 106
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ K K+ + ++ ++Y H N I+HRD+K ENVLL
Sbjct: 107 YIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLD--------------- 151
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
S+ +++ DFGL + T CGS +Y +PE++ G PY G D W+ GVI YA
Sbjct: 152 --SQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPY-GPDVDIWSCGVILYA 208
Query: 459 LLEDRLPFD 467
LL LPFD
Sbjct: 209 LLCGTLPFD 217
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 87.8 bits (216), Expect = 4e-17
Identities = 52/148 (35%), Positives = 79/148 (53%), Gaps = 20/148 (13%)
Query: 322 LPRCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENV 380
+ R +M Y GGDL F + K + E++ + +LH I++RD+KL+NV
Sbjct: 421 MDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLDNV 480
Query: 381 LLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLG 439
LL + V++ADFG+CK+ I D+ T CG+ DY++PEI+L
Sbjct: 481 LLD-----------------ADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILY 523
Query: 440 LPYDGRISDAWAFGVITYALLEDRLPFD 467
PY G+ D WA+GV+ Y +L + PFD
Sbjct: 524 QPY-GKSVDWWAYGVLLYEMLVGQPPFD 550
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 87.8 bits (216), Expect = 4e-17
Identities = 88/318 (27%), Positives = 135/318 (41%), Gaps = 72/318 (22%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPEL-KYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
K IG+GN++ V I + E K VAVK I + +PS K
Sbjct: 72 KVIGTGNYAKV----------KIGFSEEYGKRVAVKIISKVK------APSEYTQK---- 111
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
L RE+ + +HH ++ + +T+ H +Y +IM
Sbjct: 112 ----FLPREIEAVKGLHHENLITFYQSIETS-----HRVY------------LIMQLAEN 150
Query: 335 GDLFDLASKTKIPNWLLTR-IITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G L D + K + +R + +L A++Y+H ++HRDIK EN+LL D+ LK
Sbjct: 151 GTLLDYVRERKFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLL----DENWNLK 206
Query: 394 EDESQFFSKNFVELADFGLCKKITPDE-----MCTTRCGSEDYVSPEILLGLPYDGRISD 448
L DFG +K T + T CGS Y SPEIL G+ YD +SD
Sbjct: 207 -------------LIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGVAYDPFMSD 253
Query: 449 AWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNT 508
WA GV+ YA++ RLP+D + RI + + K+ K ++ +
Sbjct: 254 IWACGVVCYAMVFGRLPYD------GSNVHILLKRINQ-SLVFPKSPSASSECKHMIMHI 306
Query: 509 LVRKSERWNMDQLCNTPY 526
L R+N+ Q+ P+
Sbjct: 307 LAPVKIRYNIPQVKEDPW 324
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 87.4 bits (215), Expect = 5e-17
Identities = 69/254 (27%), Positives = 115/254 (45%), Gaps = 44/254 (17%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L +E+ + V HP IV+L+ + DT + LY +I+ GD+FD
Sbjct: 60 LFQEVRCMKLVQHPNIVRLYEVIDT-----QTKLY------------LILELGDEGDMFD 102
Query: 340 LASKTK--IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
K + + L + ++ AI Y H ++HRD+K ENV+
Sbjct: 103 YIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVF--------------- 147
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
F + V+L DFG K P + TT CGS Y +PEILLG YD D W+ GVI +
Sbjct: 148 -FEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILF 206
Query: 458 ALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVR-KSERW 516
L+ + PF Q + + ++ + D K+ + K+++ L R R
Sbjct: 207 MLVCGQPPF-----QEANDSETLTMIM---DCKYTVPSHVSKECKDLITRMLQRDPKRRA 258
Query: 517 NMDQLCNTPYIRNI 530
+++++ N P+++ +
Sbjct: 259 SLEEIENHPWLQGV 272
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 87.4 bits (215), Expect = 5e-17
Identities = 70/257 (27%), Positives = 121/257 (46%), Gaps = 48/257 (18%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L RE+ L +V+H I+K + I F T + +Y +IM GDL +
Sbjct: 57 LPREMDILATVNHGSIIKTYEI----FETSDGRIY------------IIMELGVQGDLLE 100
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ + + + ++ +LS A+KY HD I+HRD+K EN+LL
Sbjct: 101 FIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL---------------- 144
Query: 399 FFSKNF-VELADFGLCKKITPDE-----MCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
K+F ++L+DFG K+ D + T CGS Y +PE+L +PY ++ D W+
Sbjct: 145 --DKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSL 202
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK 512
GVI Y ++ +P+D S R + R D+ KN + K+++ L
Sbjct: 203 GVILYIMVCGSMPYD----DSDIRKMLRIQKEHRVDFPRSKNLTCE--CKDLIYRMLQPD 256
Query: 513 -SERWNMDQLCNTPYIR 528
S+R ++D++ + +++
Sbjct: 257 VSQRLHIDEILSHSWLQ 273
>7303111 [T] KOG0695 Serine/threonine protein kinase
Length = 690
Score = 87.4 bits (215), Expect = 5e-17
Identities = 50/146 (34%), Positives = 81/146 (55%), Gaps = 20/146 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R ++ + GGDL + + + ++P E+S+A+ +LH+ II+RD+KL+NVLL
Sbjct: 334 RLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLL 393
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
+ + ++L D+G+CK+ I P + +T CG+ +Y++PEIL G
Sbjct: 394 DH-----------------EGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGED 436
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G D WA GV+ Y +L R PFD
Sbjct: 437 Y-GFSVDWWALGVLLYEMLAGRSPFD 461
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 87.0 bits (214), Expect = 6e-17
Identities = 73/255 (28%), Positives = 117/255 (45%), Gaps = 65/255 (25%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
++ +G+G+F V+L I +Y A+K +K KE++
Sbjct: 90 LRTLGTGSFGRVHL---------IRSRHNGRYYAMKVLK----------------KEIVV 124
Query: 275 RV--VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYC 332
R+ V E L V HP I++++ TF D ++ MIM Y
Sbjct: 125 RLKQVEHTNDERLMLSIVTHPFIIRMWG----TF-QDAQQIF------------MIMDYI 167
Query: 333 TGGDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMML 391
GG+LF L K+ + PN + E+ +A++YLH II+RD+K EN+LL
Sbjct: 168 EGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLD-------- 219
Query: 392 LKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWA 451
+++ DFG K + PD + T CG+ DY++PE++ PY+ I D W+
Sbjct: 220 ---------KNGHIKITDFGFAKYV-PD-VTYTLCGTPDYIAPEVVSTKPYNKSI-DWWS 267
Query: 452 FGVITYALLEDRLPF 466
FG++ Y +L PF
Sbjct: 268 FGILIYEMLAGYTPF 282
>Hs20535816 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 87.0 bits (214), Expect = 6e-17
Identities = 50/163 (30%), Positives = 84/163 (50%), Gaps = 20/163 (12%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R +++ Y GGDL F + + K+P E+ +A+ +LH+ II+RD+KL+NVLL
Sbjct: 325 RLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLL 384
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
+ ++L D+G+CK+ + P + +T CG+ +Y++PEIL G
Sbjct: 385 D-----------------ADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEE 427
Query: 442 YDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRI 484
Y G D WA GV+ + ++ R PFD + T ++
Sbjct: 428 Y-GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQV 469
>Hs10864650 [T] KOG0695 Serine/threonine protein kinase
Length = 592
Score = 87.0 bits (214), Expect = 6e-17
Identities = 50/163 (30%), Positives = 84/163 (50%), Gaps = 20/163 (12%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R +++ Y GGDL F + + K+P E+ +A+ +LH+ II+RD+KL+NVLL
Sbjct: 325 RLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLL 384
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
+ ++L D+G+CK+ + P + +T CG+ +Y++PEIL G
Sbjct: 385 D-----------------ADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEE 427
Query: 442 YDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRI 484
Y G D WA GV+ + ++ R PFD + T ++
Sbjct: 428 Y-GFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQV 469
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 86.7 bits (213), Expect = 8e-17
Identities = 81/318 (25%), Positives = 136/318 (42%), Gaps = 73/318 (22%)
Query: 161 NRVVEKPSLKKETIINEVI---------TSVPS-DKENEQKADGTIIRGYMANTPNHISF 210
N+V ++ S + ++ +E + T V D ++ G I G N+ F
Sbjct: 292 NQVTQRASRRSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIF 351
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
K +G G+F V L E L +Y A+K++K L+ + K
Sbjct: 352 H----KVLGKGSFGKVLLGE---------LKGRGEYFAIKALKKDVVLIDDDVECTMVEK 398
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+L+ ++ +P + L TF T +H + +M
Sbjct: 399 RVLT-------------LAAENPFLTHLIC----TFQTKDHLFF-------------VME 428
Query: 331 YCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
+ GGDL + + K + + T E+ +++LH II+RD+KL+NVLL
Sbjct: 429 FLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLD------ 482
Query: 390 MLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
+++ADFG+CK+ I + +T CG+ DY++PEIL GL Y + D
Sbjct: 483 -----------RDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSV-D 530
Query: 449 AWAFGVITYALLEDRLPF 466
W+FGV+ Y +L + PF
Sbjct: 531 WWSFGVLLYEMLIGQSPF 548
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 86.7 bits (213), Expect = 8e-17
Identities = 75/250 (30%), Positives = 115/250 (46%), Gaps = 60/250 (24%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+GSG FS V+L + K A+K IK SP +++
Sbjct: 29 LGSGAFSEVFL---------VKQRLTGKLFALKCIK-----------KSPAFRD------ 62
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
SSL+ E+ L + H IV L I ++T ++M +GG+L
Sbjct: 63 SSLENEIAVLKKIKHENIVTLEDIYEST-----------------THYYLVMQLVSGGEL 105
Query: 338 FD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDE 396
FD + + + +I ++ A+KYLH+N I+HRD+K EN+L L E+
Sbjct: 106 FDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLL--------YLTPEEN 157
Query: 397 SQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
S+ + + DFGL K+ + + +T CG+ YV+PE+L PY + D W+ GVIT
Sbjct: 158 SK------IMITDFGL-SKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAV-DCWSIGVIT 209
Query: 457 YALLEDRLPF 466
Y LL PF
Sbjct: 210 YILLCGYPPF 219
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 86.3 bits (212), Expect = 1e-16
Identities = 81/318 (25%), Positives = 136/318 (42%), Gaps = 73/318 (22%)
Query: 161 NRVVEKPSLKKETIINEVI---------TSVPS-DKENEQKADGTIIRGYMANTPNHISF 210
N+V ++ S + ++ +E + T V D ++ G I G N+ F
Sbjct: 292 NQVTQRASRRSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFIF 351
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
K +G G+F V L E L +Y A+K++K L+ + K
Sbjct: 352 H----KVLGKGSFGKVLLGE---------LKGRGEYSAIKALKKDVVLIDDDVECTMVEK 398
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+L+ ++ +P + L TF T +H + +M
Sbjct: 399 RVLT-------------LAAENPFLTHLIC----TFQTKDHLFF-------------VME 428
Query: 331 YCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
+ GGDL + + K + + T E+ +++LH II+RD+KL+NVLL
Sbjct: 429 FLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLD------ 482
Query: 390 MLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
+++ADFG+CK+ I + +T CG+ DY++PEIL GL Y + D
Sbjct: 483 -----------RDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSV-D 530
Query: 449 AWAFGVITYALLEDRLPF 466
W+FGV+ Y +L + PF
Sbjct: 531 WWSFGVLLYEMLIGQSPF 548
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 86.3 bits (212), Expect = 1e-16
Identities = 67/266 (25%), Positives = 123/266 (46%), Gaps = 45/266 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
K+ L++ + L +E+ L + H IV L+ + + +Y ++M
Sbjct: 50 KKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMA-----NSVY------------LVM 92
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
YC GGDL D L + + + + +++ A++ LH IIHRD+K +N+LL
Sbjct: 93 EYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLS----- 147
Query: 389 MMLLKEDESQFFSKNF--VELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRI 446
+ + N V++ADFG + + + M T CGS Y++PE+++ YDG+
Sbjct: 148 -----NPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGK- 201
Query: 447 SDAWAFGVITYALLEDRLPFDPLPGQSSR----RTRSIAHRIARCDWKWLKNADTDHPAK 502
+D W+ G I Y L + PF Q R + +++ I R +T P +
Sbjct: 202 ADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPR---------ETSAPLR 252
Query: 503 EIVQNTLVRK-SERWNMDQLCNTPYI 527
+++ L R +R + D+ + P++
Sbjct: 253 QLLLALLQRNHKDRMDFDEFFHHPFL 278
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 86.3 bits (212), Expect = 1e-16
Identities = 62/238 (26%), Positives = 104/238 (43%), Gaps = 67/238 (28%)
Query: 327 MIMSYCTGGDLFDLASKT--------KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLE 378
+++ YC GGD+ + K K+ WL+ +L +A++YLH + I+HRD+K
Sbjct: 79 IVIGYCKGGDMAEAIKKANGVEFSEEKLCKWLV-----QLLMALEYLHASHILHRDVKCS 133
Query: 379 NVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILL 438
N+ L D + L DFGL K +T D++ ++ G+ Y+ PE+L
Sbjct: 134 NIFLTKDQD-----------------IRLGDFGLAKILTSDDLASSVVGTPSYMCPELLA 176
Query: 439 GLPYDGRISDAWAFGVITYALLEDRLPFD-----------------PLPGQSSRRTRSIA 481
+PY G SD W+ G Y + + F PLP Q S RS+
Sbjct: 177 DIPY-GSKSDIWSLGCCMYEMTALKPAFKAFDMQGLINRINRSIVAPLPAQYSTAFRSLV 235
Query: 482 HRIARCDWKWLKNADTDHPAKEIVQNTLVRKSERWNMDQLCNTPYIRNIIDKLQFLDH 539
+ R KN + A ++++ L++ PY++ ++ KL F +H
Sbjct: 236 KSMLR------KNPELRPSASDLLRQPLLQ-------------PYVQKVLLKLSFREH 274
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 86.3 bits (212), Expect = 1e-16
Identities = 68/252 (26%), Positives = 110/252 (42%), Gaps = 57/252 (22%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
++IGSG+FS V+ D VA+K I R L +
Sbjct: 16 RQIGSGSFSVVWEARHRVDGTE---------VAIKEIAMDR---------------LNKK 51
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ SL E+ L ++HP I++L + + + + +++ YC GG
Sbjct: 52 LQESLMSEIFILRRINHPNIIRLIDM-----------------IKSPGKVHLVLEYCKGG 94
Query: 336 DLFDLASKTKI-PNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
DL + I P + +L+ ++ L DN IIHRD+K +N+LL +D L
Sbjct: 95 DLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNNIIHRDLKPQNLLLSTNENDADL--- 151
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++ADFG + + P + T CGS Y++PEI+ YD + +D W+ G
Sbjct: 152 -----------KIADFGFARSLQPRGLAETLCGSPLYMAPEIMQLQKYDAK-ADLWSVGA 199
Query: 455 ITYALLEDRLPF 466
I + L+ R PF
Sbjct: 200 ILFQLVTGRTPF 211
>SPBC12D12.04c [T] KOG0694 Serine/threonine protein kinase
Length = 1016
Score = 85.9 bits (211), Expect = 1e-16
Identities = 71/250 (28%), Positives = 110/250 (43%), Gaps = 56/250 (22%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G GNF V L E L E + A+K +K +E ++ + E +V
Sbjct: 689 LGKGNFGKVMLAE---------LKSEKQLYAIKVLK--KEFILENDEVESTKSEKRVFLV 737
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
++ +R HP +V L + T R +M + +GGDL
Sbjct: 738 ANRER---------HPFLVNLHSCFQTE-----------------TRIYFVMDFVSGGDL 771
Query: 338 FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ + E+ +A+KY HDN II+RD+KL+N+LL
Sbjct: 772 MLHIQQEQFSRRRAQFYAAEVCLALKYFHDNGIIYRDLKLDNILLS-------------- 817
Query: 398 QFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
V++AD+GLCK+ + D T CG+ ++++PEILL Y R D WAFGV+
Sbjct: 818 ---PDGHVKVADYGLCKEDMWHDNTTATFCGTPEFMAPEILLEQQYT-RSVDWWAFGVLI 873
Query: 457 YALLEDRLPF 466
Y +L + PF
Sbjct: 874 YQMLLGQSPF 883
>CE17354 [T] KOG0694 Serine/threonine protein kinase
Length = 567
Score = 85.9 bits (211), Expect = 1e-16
Identities = 73/255 (28%), Positives = 118/255 (45%), Gaps = 60/255 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K +G G+F V L E N ++ A+K +K +++++ + Y E
Sbjct: 241 LKVLGKGSFGKVMLVELKGKN---------EFYAMKCLK--KDVILEDDDTECTYIERRV 289
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+++S P + +LF +F T+E+ + +M Y G
Sbjct: 290 LILAS-----------QCPFLCQLFC----SFQTNEYLFF-------------VMEYLNG 321
Query: 335 GDLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
GDL + K + TR E+ VA+++LH N II+RD+KL+NVLL
Sbjct: 322 GDLMHHIQQIKKFDEARTRFYACEIVVALQFLHTNNIIYRDLKLDNVLLD---------- 371
Query: 394 EDESQFFSKNFVELADFGLCKKITPDE--MCTTRCGSEDYVSPEILLGLPYDGRISDAWA 451
++LADFG+ K E M +T CG+ DY+SPEI+ G Y+ + D W+
Sbjct: 372 -------CDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAV-DFWS 423
Query: 452 FGVITYALLEDRLPF 466
FGV+ Y +L + PF
Sbjct: 424 FGVLMYEMLVGQSPF 438
>CE17353 [T] KOG0694 Serine/threonine protein kinase
Length = 704
Score = 85.9 bits (211), Expect = 1e-16
Identities = 73/255 (28%), Positives = 118/255 (45%), Gaps = 60/255 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K +G G+F V L E N ++ A+K +K +++++ + Y E
Sbjct: 378 LKVLGKGSFGKVMLVELKGKN---------EFYAMKCLK--KDVILEDDDTECTYIERRV 426
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+++S P + +LF +F T+E+ + +M Y G
Sbjct: 427 LILAS-----------QCPFLCQLFC----SFQTNEYLFF-------------VMEYLNG 458
Query: 335 GDLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
GDL + K + TR E+ VA+++LH N II+RD+KL+NVLL
Sbjct: 459 GDLMHHIQQIKKFDEARTRFYACEIVVALQFLHTNNIIYRDLKLDNVLLD---------- 508
Query: 394 EDESQFFSKNFVELADFGLCKKITPDE--MCTTRCGSEDYVSPEILLGLPYDGRISDAWA 451
++LADFG+ K E M +T CG+ DY+SPEI+ G Y+ + D W+
Sbjct: 509 -------CDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAV-DFWS 560
Query: 452 FGVITYALLEDRLPF 466
FGV+ Y +L + PF
Sbjct: 561 FGVLMYEMLVGQSPF 575
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 85.5 bits (210), Expect = 2e-16
Identities = 65/234 (27%), Positives = 105/234 (44%), Gaps = 40/234 (17%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++ E+ L+ + HP I+KL I +T +++ TGG+LFD
Sbjct: 86 VRTEIGVLLRLSHPNIIKLKEIFETP-----------------TEISLVLELVTGGELFD 128
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ K + ++ A+ YLH+N I+HRD+K EN+L D L
Sbjct: 129 RIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPL------- 181
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
++ADFGL K + + T CG+ Y +PEIL G Y + D W+ G+ITY
Sbjct: 182 -------KIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEV-DMWSVGIITYI 233
Query: 459 LLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKN--ADTDHPAKEIVQNTLV 510
LL PF R + + RI C++ ++ + AK++V+ +V
Sbjct: 234 LLCGFEPF-----YDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIV 282
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 85.1 bits (209), Expect = 2e-16
Identities = 65/253 (25%), Positives = 115/253 (44%), Gaps = 61/253 (24%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
++ +G+G+F V+L + + +Y A+K +K K + +
Sbjct: 73 MRTLGTGSFGRVHLVRSVHNG---------RYYAIKVLK--------------KQQVVKM 109
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ V E L V HP +++++ TF D ++ M+M Y G
Sbjct: 110 KQVEHTNDERRMLKLVEHPFLIRMWG----TF-QDARNIF------------MVMDYIEG 152
Query: 335 GDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LF L K+ + PN + E+ +A++YLH + II+RD+K EN+LL
Sbjct: 153 GELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLD---------- 202
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+++ DFG K++ + T CG+ DY++PE++ PY+ + D W+ G
Sbjct: 203 -------RNGHIKITDFGFAKEV--QTVTWTLCGTPDYIAPEVITTKPYNKSV-DWWSLG 252
Query: 454 VITYALLEDRLPF 466
V+ Y +L PF
Sbjct: 253 VLIYEMLAGYTPF 265
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 85.1 bits (209), Expect = 2e-16
Identities = 54/192 (28%), Positives = 89/192 (46%), Gaps = 35/192 (18%)
Query: 277 VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGD 336
+ + RE+ + + HP I+KL+ + +T + LY ++ Y G+
Sbjct: 61 LEKIYREVQIMKMLDHPHIIKLYQVMETKSM-----LY------------LVTEYAKNGE 103
Query: 337 LFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+FD LA+ ++ R ++ A+ Y H I+HRD+K EN+LL ++
Sbjct: 104 IFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMN-------- 155
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+++ADFG E+ T CGS Y +PE+ G Y+G D W+ GV+
Sbjct: 156 ---------IKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVV 206
Query: 456 TYALLEDRLPFD 467
Y L+ LPFD
Sbjct: 207 LYVLVCGALPFD 218
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 85.1 bits (209), Expect = 2e-16
Identities = 69/253 (27%), Positives = 118/253 (46%), Gaps = 43/253 (16%)
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
S + +E+ + V H IV+L+ + DT + ++ +L D I+ + G
Sbjct: 69 SQIMKEVRCMKLVQHANIVRLYEVLDT-----QTKIFLILELGDYDLHDFIIKHEKG--- 120
Query: 338 FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ L + ++ AI Y H ++HRD+K ENV+
Sbjct: 121 --------VCESLAQQYFCQIMTAIDYCHQLHVVHRDLKPENVV---------------- 156
Query: 398 QFFSK-NFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
FF K V+L DFG P E T CGS Y +PEILLG YD D W+ GVI
Sbjct: 157 -FFEKLGMVKLTDFGFSNSYEPGEQLNTSCGSLAYSAPEILLGDSYDAPAVDVWSLGVIL 215
Query: 457 YALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK-SER 515
Y L+ RLPF Q + + ++ +I C + + + +D + ++Q+ LVR+ +R
Sbjct: 216 YMLVCGRLPF-----QEANDSETLT-KILDCKYS-IPDVLSDE-CRNLIQSMLVREPQKR 267
Query: 516 WNMDQLCNTPYIR 528
+++++ +T +++
Sbjct: 268 ASLEKIVSTSWVQ 280
>YPL141c [T] KOG0583 Serine/threonine protein kinase
Length = 865
Score = 84.7 bits (208), Expect = 3e-16
Identities = 67/229 (29%), Positives = 107/229 (46%), Gaps = 50/229 (21%)
Query: 245 KYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDT 304
K VA+K IK S S+ KE+ + RE+ L + HP IVKL
Sbjct: 75 KQVAIKLIK-------RDSISNDYRKEV------KIYREINALKHLSHPNIVKL------ 115
Query: 305 TFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIK 363
E L R + +++ Y GG+ + + K ++ R+ ++L +
Sbjct: 116 -----EEVLQNSRYIG------IVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVH 164
Query: 364 YLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKI-TPDEMC 422
Y+H ++HRD+KLEN+LL ++N V + DFG + + +E+
Sbjct: 165 YIHSKGLVHRDLKLENLLLDK----------------NENLV-ITDFGFVNEFCSRNELM 207
Query: 423 TTRCGSEDYVSPEILLGL-PYDGRISDAWAFGVITYALLEDRLPFDPLP 470
T CGS Y +PE+++ PY+ R +D W+ GVI YA+L LP+D P
Sbjct: 208 KTSCGSPCYAAPELVISAEPYEARKADIWSCGVILYAILAGYLPWDDDP 256
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 84.7 bits (208), Expect = 3e-16
Identities = 68/239 (28%), Positives = 108/239 (44%), Gaps = 42/239 (17%)
Query: 236 LNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCI 295
L INL E Y VKS R + + K + L RE+ L ++H I
Sbjct: 14 LGINLG-EGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSI 72
Query: 296 VKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLA-SKTKIPNWLLTRI 354
+K + I F T +Y ++M GDL +L ++ + +
Sbjct: 73 IKTYEI----FETSHGKVY------------IVMELAVQGDLLELIKTRGALHEDEARKK 116
Query: 355 ITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNF-VELADFGLC 413
+LS+AIKY HD ++HRD+K +N+LL K+F ++L+DF
Sbjct: 117 FHQLSLAIKYCHDLDVVHRDLKCDNLLL------------------DKDFNIKLSDFSFS 158
Query: 414 KKITPDE-----MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFD 467
K+ D+ + T CGS Y +PE+L G+PY ++ D W+ GVI Y ++ +P+D
Sbjct: 159 KRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYD 217
>Hs13384594 [T] KOG0696 Serine/threonine protein kinase
Length = 697
Score = 84.7 bits (208), Expect = 3e-16
Identities = 48/146 (32%), Positives = 78/146 (52%), Gaps = 20/146 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R +M Y TGGDL + + K E+++ + +LH+ II+RD+KL+NV+L
Sbjct: 429 RLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVML 488
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
++ +++ DFG+CK+ + P T CG+ DY++PEI+ P
Sbjct: 489 D-----------------AEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQP 531
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G+ D W+FGV+ Y +L + PFD
Sbjct: 532 Y-GKSVDWWSFGVLLYEMLAGQPPFD 556
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 84.7 bits (208), Expect = 3e-16
Identities = 50/146 (34%), Positives = 77/146 (52%), Gaps = 20/146 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R +M Y GGDL F + K E++ A+++LH N +I+RD+KL+N+LL
Sbjct: 451 RLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILL 510
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
++ LADFG+CK+ I D + +T CG+ DY++PEIL +
Sbjct: 511 D-----------------AEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEME 553
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G D WA GV+ Y ++ + PF+
Sbjct: 554 Y-GVSVDWWALGVLMYEMMAGQPPFE 578
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 84.7 bits (208), Expect = 3e-16
Identities = 48/146 (32%), Positives = 72/146 (48%), Gaps = 22/146 (15%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M YC+GG++FD + K ++ +L AI ++H HRD+K EN+LL
Sbjct: 84 IVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYAHRDLKPENLLLTED 143
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM----CTTRCGSEDYVSPEILLGLP 441
L ++L DFGLC K + T CGS Y +PE++ GL
Sbjct: 144 LH-----------------LKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQGLQ 186
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G +D W+ G++ Y LL LPF+
Sbjct: 187 YKGNEADVWSMGILLYTLLVGALPFE 212
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 84.3 bits (207), Expect = 4e-16
Identities = 84/363 (23%), Positives = 152/363 (41%), Gaps = 82/363 (22%)
Query: 181 SVPSDKENEQKADGTI------IRGYMANTPNHISFQWSKI--------KEIGSGNFSTV 226
S+ + KEN++ ++ I +A P+ QW + K +G G F V
Sbjct: 73 SLANGKENKRTSNSKFNSSLRKIEEPIAGVPSSAGPQWREFHIGMFEIGKPLGKGKFGRV 132
Query: 227 YLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTT 286
YL + + ++ + EL+ S ++ ++RE+
Sbjct: 133 YLAK----------EKKTGFIVALKTLHKSELVQS-------------KIEKQVRREIEI 169
Query: 287 LISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLASKTK- 345
++ H I++L+ DE +Y +I+ + G+L+ + K
Sbjct: 170 QSNLRHKNILRLYG-----HFHDEKRIY------------LILEFAGRGELYQHLRRAKR 212
Query: 346 IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFV 405
+ ++ I +++ A+ YLH +IHRDIK EN+LL + +
Sbjct: 213 FSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGIDGE-----------------I 255
Query: 406 ELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLP 465
+L+DFG P TT CG+ DY+ PE++ G + ++ D W+ GV+TY L P
Sbjct: 256 KLSDFGWSVH-APSNRRTTLCGTLDYLPPEMVEGKEHTEKV-DLWSLGVLTYEFLVGAPP 313
Query: 466 FDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRKSE-RWNMDQLCNT 524
F+ + G S + RIA+ D K D A++++ L E R +++Q+
Sbjct: 314 FEDMSGHS-----ATYKRIAKVDLKIPSFVPPD--ARDLISRLLQHNPEKRMSLEQVMRH 366
Query: 525 PYI 527
P+I
Sbjct: 367 PWI 369
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 84.3 bits (207), Expect = 4e-16
Identities = 43/142 (30%), Positives = 71/142 (49%), Gaps = 18/142 (12%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
M+ + GG + D + S K+ + + ++ A+ YLH N ++HRD+K+EN+L+ T
Sbjct: 218 MVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKT 277
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
D +++ DFGL T CGS + +PE+L PY G
Sbjct: 278 GD-----------------IKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYIGP 320
Query: 446 ISDAWAFGVITYALLEDRLPFD 467
D W+FG++ Y L+ ++PFD
Sbjct: 321 EVDVWSFGIVLYVLVCGKVPFD 342
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 84.3 bits (207), Expect = 4e-16
Identities = 78/251 (31%), Positives = 114/251 (45%), Gaps = 60/251 (23%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G+G FS V+L E D + AVK I K+ L
Sbjct: 28 LGTGAFSKVFLAESKSDAGQM--------YAVKCID----------------KKALKGKE 63
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
SL+ E+ L + H IV+LF D ++ +Y ++M TGG+L
Sbjct: 64 ESLENEIKVLRKLRHNNIVQLFDTYD-----EKQFVY------------LVMELVTGGEL 106
Query: 338 FD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDE 396
FD + +K + +I ++ A+ ++HDN ++HRD+K EN LL Y D ED
Sbjct: 107 FDRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPEN-LLYYNQD------EDS 159
Query: 397 SQFFSKNFVELADFGLCKKITPDE-MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
+ ++DFGL K T D + T CG+ YV+PE+L PY G+ D W+ GVI
Sbjct: 160 K-------IMISDFGLSK--TEDSGVMATACGTPGYVAPEVLQQKPY-GKAVDVWSIGVI 209
Query: 456 TYALLEDRLPF 466
Y LL PF
Sbjct: 210 AYILLCGYPPF 220
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 84.3 bits (207), Expect = 4e-16
Identities = 56/194 (28%), Positives = 90/194 (45%), Gaps = 37/194 (19%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
++ +KRE++ + V HP IV+L + ++ + IM Y GG
Sbjct: 56 MMEQIKREISIMRLVRHPNIVEL-----------------KEVMATKTKIFFIMEYVKGG 98
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LF K K+ + +L A+ + H + HRD+K EN+L+ D
Sbjct: 99 ELFSKIVKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGD-------- 150
Query: 396 ESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++++DFGL ++I D + T+CG+ YV+PE+L YDG D W+
Sbjct: 151 ---------LKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDGAKGDIWSC 201
Query: 453 GVITYALLEDRLPF 466
G+I Y LL LPF
Sbjct: 202 GIILYVLLAGFLPF 215
>At3g44200 [R] KOG0589 Serine/threonine protein kinase
Length = 941
Score = 84.3 bits (207), Expect = 4e-16
Identities = 46/143 (32%), Positives = 73/143 (50%), Gaps = 21/143 (14%)
Query: 327 MIMSYCTGGDLFDLASKTK---IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLK 383
++ YC GGD+ +L K+ P L + T+L +A++YLH N+++HRD+K N+ L
Sbjct: 83 IVTGYCEGGDMAELMKKSNGVYFPEEKLCKWFTQLLLAVEYLHSNYVLHRDLKCSNIFLT 142
Query: 384 YTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYD 443
D V L DFGL K + D++ ++ G+ +Y+ PE+L +PY
Sbjct: 143 KDQD-----------------VRLGDFGLAKTLKADDLTSSVVGTPNYMCPELLADIPY- 184
Query: 444 GRISDAWAFGVITYALLEDRLPF 466
G SD W+ G Y + R F
Sbjct: 185 GFKSDIWSLGCCIYEMAAYRPAF 207
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 84.0 bits (206), Expect = 5e-16
Identities = 65/185 (35%), Positives = 88/185 (47%), Gaps = 34/185 (18%)
Query: 283 ELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LA 341
E+ + S+ HP IVKL + +T + +Y +I+ Y GGDLFD +
Sbjct: 330 EILIIQSLSHPNIVKLHEVYET-----DMEIY------------LILEYVQGGDLFDAII 372
Query: 342 SKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFS 401
K P +I +L A+ ++HD I+HRD+K EN+L++ D LK
Sbjct: 373 ESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLK-------- 424
Query: 402 KNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLE 461
LADFGL K + T CG+ YV+PEIL Y G D WA GVI Y LL
Sbjct: 425 -----LADFGLAKHVV--RPIFTVCGTPTYVAPEILSEKGY-GLEVDMWAAGVILYILLC 476
Query: 462 DRLPF 466
PF
Sbjct: 477 GFPPF 481
>At4g33950 [T] KOG0583 Serine/threonine protein kinase
Length = 357
Score = 84.0 bits (206), Expect = 5e-16
Identities = 76/294 (25%), Positives = 120/294 (39%), Gaps = 64/294 (21%)
Query: 193 DGTIIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSI 252
D + G M H S ++ +K+IGSGNF L N + VAVK
Sbjct: 2 DRPAVSGPMDLPIMHDSDRYELVKDIGSGNFGVARLMRDKQSN---------ELVAVK-- 50
Query: 253 KYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHP 312
Y E ++ ++KRE+ S+ HP IV+ + +T H
Sbjct: 51 ----------------YIERGEKIDENVKREIINHRSLRHPNIVRFKEV----ILTPTH- 89
Query: 313 LYGRRKLSALPRCDMIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFII 371
++M Y +GG+LF+ + + + +L + Y H +
Sbjct: 90 ------------LAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHAMQVC 137
Query: 372 HRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDY 431
HRD+KLEN LL + + ++ DFG K + G+ Y
Sbjct: 138 HRDLKLENTLLDGSPAPRL---------------KICDFGYSKSSVLHSQPKSTVGTPAY 182
Query: 432 VSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRI 484
++PE+LL YDG+++D W+ GV Y +L PF DP ++ R+T HRI
Sbjct: 183 IAPEVLLKKEYDGKVADVWSCGVTLYVMLVGAYPFEDPEEPKNFRKT---IHRI 233
>YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 83.6 bits (205), Expect = 7e-16
Identities = 106/470 (22%), Positives = 191/470 (40%), Gaps = 56/470 (11%)
Query: 81 QVEKRRNKDSASNSGVPSPTISSVDTHEEVLDEELSKLGTYMNRDVTHKIKGRMLSEYIP 140
Q+ K + V P++ + D H + L +EL VT S+ I
Sbjct: 42 QITSSPKKSFQDKNIVQYPSVVADDHHMKSLTDEL----------VTTIDSDSSPSDNIT 91
Query: 141 NNSMGDGSGGVAVQRSISLNNRVVEKPSLKKETII--NEVITSVPSDKENEQKADGTIIR 198
++ + A+ S ++ P + E++ +E+I+ + D ++ + I
Sbjct: 92 TENVETVTSVPAIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPE 151
Query: 199 GYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPREL 258
I ++ I +IG G FS V+ ++ N L K VA+K IK +
Sbjct: 152 KSFLEQKELIGYKL--INKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIK--KAD 207
Query: 259 LMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRK 318
L S + K + +S + ++ +++H I + Y
Sbjct: 208 LSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYY--- 264
Query: 319 LSALPRCDMIMSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKL 377
+I TGG++F ++ T L +I +L++A+K++H ++HRDIK
Sbjct: 265 --------IIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKP 316
Query: 378 ENVLL-----------KYTLDDMMLLKEDESQFF------SKNFVELADFGLCKKITPDE 420
EN+L K D K DE F V+LADFGL K+I +
Sbjct: 317 ENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIF-SK 375
Query: 421 MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSI 480
T CG+ Y +PE++ Y ++ D W G + Y +L PF + ++
Sbjct: 376 NTKTPCGTVGYTAPEVVKDEHYSMKV-DMWGIGCVLYTMLCGFPPF------YDEKIDTL 428
Query: 481 AHRIARCDWKWLKN--ADTDHPAKEIVQNTL-VRKSERWNMDQLCNTPYI 527
+I+R ++ +LK + AK V L + S+R+++DQ + P++
Sbjct: 429 TEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWL 478
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 83.6 bits (205), Expect = 7e-16
Identities = 95/396 (23%), Positives = 152/396 (37%), Gaps = 84/396 (21%)
Query: 80 LQVEKRRNKDSASNSGVPSPTISSVDTHEEVLDEELSKLGTYMNRDV--------THKIK 131
L+V KR K N + T+E+V + LS T+ T +
Sbjct: 452 LEVSKRPKKPELPNQ-------ENKTTNEKVYRKPLSSQNTFDTLPTISQGLLAATQPVT 504
Query: 132 GRMLSEYIPNNSMGDGSGGVAVQRSISLNNRVVEKPSLKKETIINEVITSVPSDKENEQK 191
+ + +P D S V S V+ PS + + SVP E+K
Sbjct: 505 SVLNTSPLPKTPEKDRSLNVTPSSSTPTPASVLAPPSSASLSSSKDANRSVPESPRREKK 564
Query: 192 ADGTIIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKS 251
T+ ++ + +G GNF V L E K+ A+K
Sbjct: 565 NRVTLD-------------DFTFLAVLGKGNFGKVMLAE---------YKVNKKFYAIKV 602
Query: 252 IKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEH 311
+K +L + S K ++ + V + K HP ++ LFA T+
Sbjct: 603 LK-KEAILKNEELESLKTEKHVFEVANKEK----------HPFLLNLFASFQTS------ 645
Query: 312 PLYGRRKLSALPRCDMIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFII 371
R +M Y GGDL + + E+ +A+KY H+N I
Sbjct: 646 -----------TRVYFVMEYILGGDLMVHIQRQQFSVKRARFYGAEVCLALKYFHENGIA 694
Query: 372 HRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSED 430
+RD+KL+N+LL + +AD+GLCK+ + +T CG+ +
Sbjct: 695 YRDLKLDNILL-----------------CPDGHIRIADYGLCKENMLLGNTTSTFCGTPE 737
Query: 431 YVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
+++PEILL Y + D WAFGV+ Y +L + PF
Sbjct: 738 FMAPEILLEQQYSKDV-DWWAFGVLMYQMLLGQSPF 772
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 83.6 bits (205), Expect = 7e-16
Identities = 72/298 (24%), Positives = 130/298 (43%), Gaps = 48/298 (16%)
Query: 245 KYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDT 304
K VA+K I + + S+ + P +++ E+ L ++HPCI+K+
Sbjct: 244 KKVAIKIISKRKFAIGSAREADPAL---------NVETEIEILKKLNHPCIIKI------ 288
Query: 305 TFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIK 363
D Y +++ GG+LFD + ++ ++ +A++
Sbjct: 289 KNFFDAEDYY------------IVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQ 336
Query: 364 YLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCT 423
YLH+N IIHRD+K ENVLL +D + +++ DFG K + +
Sbjct: 337 YLHENGIIHRDLKPENVLLSSQEEDCL--------------IKITDFGHSKILGETSLMR 382
Query: 424 TRCGSEDYVSPEILLGLPYDG--RISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIA 481
T CG+ Y++PE+L+ + G R D W+ GVI + L PF Q S + + +
Sbjct: 383 TLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITS 442
Query: 482 HRIARCDWKWLKNADTDHPAKEIVQNTL-VRKSERWNMDQLCNTPYIRNIIDKLQFLD 538
+ W A+ A ++V+ L V R+ ++ P++++ K +F D
Sbjct: 443 GKYNFIPEVW---AEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD 497
>Hs14776113 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 424
Score = 83.6 bits (205), Expect = 7e-16
Identities = 58/188 (30%), Positives = 88/188 (45%), Gaps = 35/188 (18%)
Query: 283 ELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LA 341
EL L V H I++L + +T R M+M TGG+LFD +
Sbjct: 143 ELRVLRRVRHANIIQLVEVFETQ-----------------ERVYMVMELATGGELFDRII 185
Query: 342 SKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFS 401
+K TR++ + ++YLH I HRD+K EN+L + D ++
Sbjct: 186 AKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKII--------- 236
Query: 402 KNFVELADFGL--CKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYAL 459
+ DFGL +K D + T CG+ +Y++PE+L+ PY + D WA GVI Y L
Sbjct: 237 -----ITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSV-DMWALGVIAYIL 290
Query: 460 LEDRLPFD 467
L +PF+
Sbjct: 291 LSGTMPFE 298
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 82.8 bits (203), Expect = 1e-15
Identities = 53/166 (31%), Positives = 85/166 (50%), Gaps = 29/166 (17%)
Query: 306 FITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF---DLASKTKIPNWLLTRIITELSVAI 362
F+T H + + R +M Y GGDL + K P+ + E+++ +
Sbjct: 402 FLTQLHSCF-----QTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF--YAAEIAIGL 454
Query: 363 KYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMC 422
+L II+RD+KL+NV+L S+ +++ADFG+CK+ D +
Sbjct: 455 FFLQSKGIIYRDLKLDNVMLD-----------------SEGHIKIADFGMCKENIWDGVT 497
Query: 423 T-TRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFD 467
T T CG+ DY++PEI+ PY G+ D WAFGV+ Y +L + PF+
Sbjct: 498 TKTFCGTPDYIAPEIIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFE 542
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 82.8 bits (203), Expect = 1e-15
Identities = 53/166 (31%), Positives = 85/166 (50%), Gaps = 29/166 (17%)
Query: 306 FITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF---DLASKTKIPNWLLTRIITELSVAI 362
F+T H + + R +M Y GGDL + K P+ + E+++ +
Sbjct: 402 FLTQLHSCF-----QTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVF--YAAEIAIGL 454
Query: 363 KYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMC 422
+L II+RD+KL+NV+L S+ +++ADFG+CK+ D +
Sbjct: 455 FFLQSKGIIYRDLKLDNVMLD-----------------SEGHIKIADFGMCKENIWDGVT 497
Query: 423 T-TRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFD 467
T T CG+ DY++PEI+ PY G+ D WAFGV+ Y +L + PF+
Sbjct: 498 TKTFCGTPDYIAPEIIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFE 542
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 82.8 bits (203), Expect = 1e-15
Identities = 48/148 (32%), Positives = 78/148 (52%), Gaps = 20/148 (13%)
Query: 322 LPRCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENV 380
+ R +M + GGDL + + K + E++V + +LH II+RD+KL+NV
Sbjct: 484 MDRLYFVMEFVNGGDLMYQIQQVGKFKEPVAVFYAAEIAVGLFFLHSKGIIYRDLKLDNV 543
Query: 381 LLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLG 439
+L+ +++ DFG+CK+ I D T CG+ DY++PEI+L
Sbjct: 544 MLE-----------------RDGHIKITDFGMCKENIFGDATTKTFCGTPDYIAPEIILY 586
Query: 440 LPYDGRISDAWAFGVITYALLEDRLPFD 467
PY G+ D WA+GV+ + +L + PFD
Sbjct: 587 QPY-GKSVDWWAYGVLLFEMLAGQPPFD 613
>At3g04810 [R] KOG0589 Serine/threonine protein kinase
Length = 606
Score = 82.8 bits (203), Expect = 1e-15
Identities = 56/205 (27%), Positives = 93/205 (45%), Gaps = 44/205 (21%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWL---LTRIITELSVAIKYLHDNFIIHRDIKLENVLLK 383
+I+ YC GGD+ + KT ++ L + + ++ +A++YLH N I+HRD+K N+ L
Sbjct: 79 IIIGYCKGGDMAEAIKKTNGVHFTEEKLCKWLVQILLALEYLHANHILHRDVKCSNIFLT 138
Query: 384 YTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYD 443
D + L DFGL K +T D++ ++ G+ Y+ PE+L +PY
Sbjct: 139 KDQD-----------------IRLGDFGLAKVLTSDDLASSVVGTPSYMCPELLADIPY- 180
Query: 444 GRISDAWAFGVITYALLEDRLPF-----------------DPLPGQSSRRTRSIAHRIAR 486
G SD W+ G Y + + F PLP Q S R + + R
Sbjct: 181 GSKSDIWSLGCCMYEMTAMKPAFKAFDMQGLINRINRSIVPPLPAQYSAAFRGLVKSMLR 240
Query: 487 CDWKWLKNADTDHPAKEIVQNTLVR 511
KN + A E+++ L++
Sbjct: 241 ------KNPELRPSAAELLRQPLLQ 259
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 82.8 bits (203), Expect = 1e-15
Identities = 67/252 (26%), Positives = 118/252 (46%), Gaps = 41/252 (16%)
Query: 283 ELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLAS 342
E + ++ HPC+V++ I D +Y M++ + GGDL +
Sbjct: 211 EAKIMKNLSHPCVVRMHDIVDKP-----DSVY------------MVLEFMRGGDLLNRII 253
Query: 343 KTKIPNWLLTRI-ITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFS 401
K+ + ++++ ++ A+KYLHD I HRD+K +NVLL+ T D+ LLK
Sbjct: 254 SNKLLSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLE-TNDEETLLK-------- 304
Query: 402 KNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILL--GLPYDGRISDAWAFGVITYAL 459
++DFGL K + D + T CG+ YV+PE+L+ G + D W+ GV+ +
Sbjct: 305 -----VSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVVLFTC 359
Query: 460 LEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRKSERW-N 517
L LPF D ++++ + WK AK ++ L+ ER +
Sbjct: 360 LSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWK-----SVSQRAKLLINQMLIVDPERRPS 414
Query: 518 MDQLCNTPYIRN 529
+D + + ++R+
Sbjct: 415 IDDVLQSSWLRD 426
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 82.4 bits (202), Expect = 2e-15
Identities = 71/264 (26%), Positives = 113/264 (41%), Gaps = 50/264 (18%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
K L + +K E+ L ++ H I +L+ + +T + M++
Sbjct: 44 KNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETA-----------------NKIFMVL 86
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
YC GG+LFD + S+ ++ + ++ A+ Y+H HRD+K EN+L D+
Sbjct: 87 EYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLF----DE 142
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKI--TPDEMCTTRCGSEDYVSPEILLGLPYDGRI 446
LK L DFGLC K D T CGS Y +PE++ G Y G
Sbjct: 143 YHKLK-------------LIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189
Query: 447 SDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDW---KWLKNADTDHPAKE 503
+D W+ G++ Y L+ LPFD ++ +I R + KWL +
Sbjct: 190 ADVWSMGILLYVLMCGFLPFD------DDNVMALYKKIMRGKYDVPKWLSPSS----ILL 239
Query: 504 IVQNTLVRKSERWNMDQLCNTPYI 527
+ Q V +R +M L N P+I
Sbjct: 240 LQQMLQVDPKKRISMKNLLNHPWI 263
>Hs16418343 [T] KOG0583 Serine/threonine protein kinase
Length = 268
Score = 82.4 bits (202), Expect = 2e-15
Identities = 56/191 (29%), Positives = 91/191 (47%), Gaps = 37/191 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L REL + ++ H I++++ + + SA + ++M GGD+FD
Sbjct: 55 LPRELQIVRTLDHKNIIQVYEMLE----------------SADGKICLVMELAEGGDVFD 98
Query: 340 -LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ + +P + ++ AI+Y H + HRD+K EN LL Q
Sbjct: 99 CVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALL---------------Q 143
Query: 399 FFSKNFVELADFGLCKKITPD--EMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
F+ ++L DFG K + E+ T CGS Y +PE+L G+P+D + D W+ GV+
Sbjct: 144 GFN---LKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVL 200
Query: 457 YALLEDRLPFD 467
Y +L LPFD
Sbjct: 201 YVMLCASLPFD 211
>CE29298 [T] KOG0690 Serine/threonine protein kinase
Length = 483
Score = 82.4 bits (202), Expect = 2e-15
Identities = 52/166 (31%), Positives = 85/166 (50%), Gaps = 26/166 (15%)
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
+M + GG+LF + K + TR +E+ +A+ YLH I++RD+KLEN+LL
Sbjct: 256 VMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRNIVYRDMKLENLLLD--- 312
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCK-KITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+++ DFGLCK +I + +T CG+ +Y++PE++ + YD R
Sbjct: 313 --------------RDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYD-R 357
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKW 491
D W GV+ Y ++ RLPF S++ + I CD K+
Sbjct: 358 SVDWWGVGVVMYEMMCGRLPF------SAKENGKLFELITTCDLKF 397
>CE18646 [T] KOG0690 Serine/threonine protein kinase
Length = 528
Score = 82.4 bits (202), Expect = 2e-15
Identities = 52/166 (31%), Positives = 85/166 (50%), Gaps = 26/166 (15%)
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
+M + GG+LF + K + TR +E+ +A+ YLH I++RD+KLEN+LL
Sbjct: 256 VMEFANGGELFTHLQRCKTFSEARTRFYGSEIILALGYLHHRNIVYRDMKLENLLLD--- 312
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCK-KITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+++ DFGLCK +I + +T CG+ +Y++PE++ + YD R
Sbjct: 313 --------------RDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAPEVIEDIDYD-R 357
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKW 491
D W GV+ Y ++ RLPF S++ + I CD K+
Sbjct: 358 SVDWWGVGVVMYEMMCGRLPF------SAKENGKLFELITTCDLKF 397
>Hs5453974 [T] KOG0694 Serine/threonine protein kinase
Length = 984
Score = 82.0 bits (201), Expect = 2e-15
Identities = 59/192 (30%), Positives = 94/192 (48%), Gaps = 46/192 (23%)
Query: 281 KRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF-- 338
KR T+ SV HP +V LFA F T EH + +M Y GGDL
Sbjct: 706 KRIFETVNSVRHPFLVNLFAC----FQTKEHVCF-------------VMEYAAGGDLMMH 748
Query: 339 ---DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
D+ S+ + + ++ ++YLH++ I++RD+KL+N+LL
Sbjct: 749 IHTDVFSEPRAVFYAACVVL-----GLQYLHEHKIVYRDLKLDNLLLD------------ 791
Query: 396 ESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++ FV++ADFGLCK+ + + +T CG+ ++++PE+L Y R D W GV
Sbjct: 792 -----TEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYT-RAVDWWGLGV 845
Query: 455 ITYALLEDRLPF 466
+ Y +L PF
Sbjct: 846 LIYEMLVGESPF 857
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 82.0 bits (201), Expect = 2e-15
Identities = 82/296 (27%), Positives = 130/296 (43%), Gaps = 49/296 (16%)
Query: 178 VITSVPSDKENEQ----KADGTIIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECID 233
V+ +P+ + +EQ ++ + G + + + ++ K IG GNF+ V ECID
Sbjct: 160 VVGPLPASRTDEQAGFMESRDPGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVK--ECID 217
Query: 234 DNLNINLNPELKYVAVKSIKYPRELLMSSSPSSP--KYKELLSRVVSSLKRELTTLISVH 291
+ K A+K I + +PS+ + ++ ++ E++ L V
Sbjct: 218 RSTG-------KEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGSTEHLIENEVSILRRVK 270
Query: 292 HPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LASKTKIPNWL 350
HP I+ L ++ ++M GGDLFD + S TK
Sbjct: 271 HPNIIMLV-----------------EEMETATELFLVMELVKGGDLFDAITSSTKYTERD 313
Query: 351 LTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADF 410
+ ++ L+ A++YLH I+HRDIK EN+L+ D LK L DF
Sbjct: 314 GSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLK-------------LGDF 360
Query: 411 GLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
GL + + T CG+ YV+PEI+ Y ++ D WA GVITY LL PF
Sbjct: 361 GLATVV--EGPLYTVCGTPTYVAPEIIAETGYGLKV-DIWAAGVITYILLCGFPPF 413
>Hs20127541 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 427
Score = 82.0 bits (201), Expect = 2e-15
Identities = 78/279 (27%), Positives = 117/279 (40%), Gaps = 62/279 (22%)
Query: 191 KADGTIIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVK 250
+A+G I G AN PN + +K IG GN+ V L + D + AVK
Sbjct: 75 RANGNINLGPSAN-PNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGA---------FYAVK 124
Query: 251 SIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLI-SVHHPCIVKLFAINDTTFITD 309
++ K L + S + E + L+ +V HP +V L
Sbjct: 125 VLQ--------------KKSILKKKEQSHIMAERSVLLKNVRHPFLVGL----------- 159
Query: 310 EHPLYGRRKLSALPRCDMIMSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDN 368
R + ++ Y GG+LF L + + E++ AI YLH
Sbjct: 160 ------RYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSL 213
Query: 369 FIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCG 427
II+RD+K EN+LL + V L DFGLCK+ + P++ +T CG
Sbjct: 214 NIIYRDLKPENILLD-----------------CQGHVVLTDFGLCKEGVEPEDTTSTFCG 256
Query: 428 SEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
+ +Y++PE+L PYD R D W G + Y +L PF
Sbjct: 257 TPEYLAPEVLRKEPYD-RAVDWWCLGAVLYEMLHGLPPF 294
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 81.6 bits (200), Expect = 3e-15
Identities = 69/213 (32%), Positives = 106/213 (49%), Gaps = 31/213 (14%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M Y GG+LF L S+ +I EL VAI LH +I+RD+KLEN+LL
Sbjct: 97 IVMEYVRGGELFTHLCSRGHFDLEAARFVIAELVVAIDSLHQRKVIYRDLKLENILL--- 153
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM--CTTRCGSEDYVSPEILLGLPYD 443
DE + V+L DFGL K P E+ + CG+ +Y+SPE+ + P
Sbjct: 154 ---------DE-----EGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPEV-INRPEG 198
Query: 444 G--RISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPA 501
G + D W+ GVI++ LL PF Q+S ++ IA RI + K D D A
Sbjct: 199 GYSDVVDWWSLGVISFELLTGCSPFTVDGAQNS--SKDIAKRIMTKKVPFPKTMDVD--A 254
Query: 502 KEIVQNTLVRKSERW----NMDQLCNTPYIRNI 530
++ + L +K E+ +D++ N ++ +I
Sbjct: 255 RDFIGQLLEKKLEKRLGYNGVDEIKNHKFMSSI 287
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/226 (25%), Positives = 95/226 (41%), Gaps = 48/226 (21%)
Query: 327 MIMSYCTGGDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M TG +L + K + I+ +L A+KYLHD I+HRD+K EN+L + +
Sbjct: 452 LVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHRDLKPENILFE-S 510
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM------------------------ 421
+D L+ L DFG ++ P+ M
Sbjct: 511 IDSSARLR-------------LVDFGFA-RLLPNSMEQQLKSVQVLRKMYGLIAHNHSLH 556
Query: 422 CTTRCGSEDYVSPEIL---LGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTR 478
T C + Y +PE+L P D W+ GV+ + +L ++PF Q S
Sbjct: 557 SETPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQES--AT 614
Query: 479 SIAHRIARCDWKWLKNADTD--HPAKEIVQNTL-VRKSERWNMDQL 521
I RI R ++ + +A T+ AK ++ L V +R +M +L
Sbjct: 615 EIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQEL 660
>At5g66880 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 81.6 bits (200), Expect = 3e-15
Identities = 73/273 (26%), Positives = 114/273 (41%), Gaps = 61/273 (22%)
Query: 207 HISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSS 266
H S ++ +K+IGSGNF L + L EL VAVK
Sbjct: 17 HDSDRYDFVKDIGSGNFGVARL-------MRDKLTKEL--VAVK---------------- 51
Query: 267 PKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCD 326
Y E ++ +++RE+ S+ HP IV+ + +T H
Sbjct: 52 --YIERGDKIDENVQREIINHRSLRHPNIVRFKEV----ILTPTH-------------LA 92
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+IM Y +GG+L++ + + + +L + Y H I HRD+KLEN LL +
Sbjct: 93 IIMEYASGGELYERICNAGRFSEDEARFFFQQLLSGVSYCHSMQICHRDLKLENTLLDGS 152
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+ ++ DFG K + G+ Y++PE+LL YDG+
Sbjct: 153 PAPRL---------------KICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLRQEYDGK 197
Query: 446 ISDAWAFGVITYALLEDRLPF-DPLPGQSSRRT 477
I+D W+ GV Y +L PF DP + R+T
Sbjct: 198 IADVWSCGVTLYVMLVGAYPFEDPEEPRDYRKT 230
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 81.6 bits (200), Expect = 3e-15
Identities = 72/280 (25%), Positives = 131/280 (46%), Gaps = 52/280 (18%)
Query: 270 KELLSR--VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
K+LL+ + +++KRE++ + + HP IVKL + ++ +
Sbjct: 55 KKLLTNPALANNIKREISIMRRLSHPNIVKLHEV-----------------MATKSKIFF 97
Query: 328 IMSYCTGGDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
M + GG+LF+ SK ++ L R +L A+ Y H + HRD+K EN+L+
Sbjct: 98 AMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLI---- 153
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCK---KITPDEMCTTRCGSEDYVSPEILLGLPYD 443
DE+ ++++DFGL +I PD + T CG+ YV+PEIL Y+
Sbjct: 154 --------DEN-----GNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE 200
Query: 444 GRISDAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAK 502
G D W+ G++ + L+ LPF DP ++ +I + ++++ + D K
Sbjct: 201 GAKVDVWSCGIVLFVLVAGYLPFNDP-------NVMNMYKKIYKGEYRFPRWMSPD--LK 251
Query: 503 EIVQNTL-VRKSERWNMDQLCNTP-YIRNIIDKLQFLDHQ 540
V L + R +D++ P ++R +++F D +
Sbjct: 252 RFVSRLLDINPETRITIDEILKDPWFVRGGFKQIKFHDDE 291
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 81.3 bits (199), Expect = 4e-15
Identities = 70/262 (26%), Positives = 122/262 (45%), Gaps = 42/262 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
K+ L SS++ E+ L + H IV L I ++ + LY ++M
Sbjct: 56 KKALKGKESSIENEIAVLRKIKHENIVALEDIYESP-----NHLY------------LVM 98
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
+GG+LFD + K + +I ++ A+ YLH I+HRD+K EN LL Y+ D+
Sbjct: 99 QLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPEN-LLYYSQDE 157
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISD 448
++ + ++DFGL K ++ +T CG+ YV+PE+L PY + D
Sbjct: 158 -------------ESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAV-D 203
Query: 449 AWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKN--ADTDHPAKEIVQ 506
W+ GVI Y LL PF + +I + ++++ D AK+ ++
Sbjct: 204 CWSIGVIAYILLCGYPPF------YDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIR 257
Query: 507 NTLVR-KSERWNMDQLCNTPYI 527
N + + ++R+ +Q P+I
Sbjct: 258 NLMEKDPNKRYTCEQAARHPWI 279
>Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1354
Score = 81.3 bits (199), Expect = 4e-15
Identities = 56/156 (35%), Positives = 77/156 (48%), Gaps = 24/156 (15%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
M+M Y GGDL +L S +P E+ +A+ +H IHRD+K +N+LL
Sbjct: 151 MVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLL---- 206
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM--CTTRCGSEDYVSPEILL---GLP 441
D+S ++LADFG C K+ + M C T G+ DY+SPE+L G
Sbjct: 207 --------DKS-----GHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDG 253
Query: 442 YDGRISDAWAFGVITYALLEDRLPF--DPLPGQSSR 475
Y GR D W+ GV Y +L PF D L G S+
Sbjct: 254 YYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSK 289
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 81.3 bits (199), Expect = 4e-15
Identities = 60/196 (30%), Positives = 97/196 (48%), Gaps = 29/196 (14%)
Query: 274 SRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
S V L+RE+ L SV H I+ L + +T + ++M C
Sbjct: 154 SSAVKLLEREVNILKSVKHEHIIHLEQVFETP-----------------KKMYLVMELCE 196
Query: 334 GGDLFDLASKTKIPNWLLTR-IITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
G+L ++ + + TR II L+ AI YLH+N I+HRD+KLEN+++K +L
Sbjct: 197 DGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSL------ 250
Query: 393 KEDESQFFSKNFVELADFGLC--KKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAW 450
D++ + N +++ DFGL K+ + M CG+ Y++PE++ Y + D W
Sbjct: 251 -IDDNNEINLN-IKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQ-CDIW 307
Query: 451 AFGVITYALLEDRLPF 466
+ GV+ Y LL PF
Sbjct: 308 SIGVVMYMLLRGEPPF 323
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 81.3 bits (199), Expect = 4e-15
Identities = 58/203 (28%), Positives = 97/203 (47%), Gaps = 27/203 (13%)
Query: 327 MIMSYCTGGDLFDLA-SKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+I Y G L+D+ S + R +L AI Y+H N ++HRD+K+EN+L+
Sbjct: 139 LIFEYVKGRQLYDIIISSGPLKEKEGQRYFRQLLSAIDYIHRNSVVHRDLKIENILI--- 195
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
DE+ + V+L DFGL + T CGS + +PE+L G Y G
Sbjct: 196 ---------DEN-----DNVKLIDFGLSNFYDNKTLLNTFCGSLYFAAPELLQGQRYCGP 241
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIV 505
D W+ GV+ YA+L +PFD + + +I D+K+ K + A E++
Sbjct: 242 EIDVWSLGVVLYAILCGCVPFD------DEDVQGLQAKIMDADFKFCKTISRE--AMELI 293
Query: 506 QNTLV-RKSERWNMDQLCNTPYI 527
+ +V + S R + Q+ + ++
Sbjct: 294 RGMIVAQPSSRMGLSQVIGSEWV 316
>CE21239 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 81.3 bits (199), Expect = 4e-15
Identities = 69/253 (27%), Positives = 114/253 (44%), Gaps = 61/253 (24%)
Query: 217 EIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRV 276
++G G +S VY + D N N + VAVK+I +EL + V
Sbjct: 99 KLGRGKYSKVY--KAFDRNNN-------RVVAVKAIDT---------------QELTTDV 134
Query: 277 -VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ L REL+ + +P +V L A + A + M Y + G
Sbjct: 135 KMKFLPRELSCWRKLKNPFVVGLHA-----------------QYEAQSMIFLTMEYGSQG 177
Query: 336 DLFDLASKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
DL + I +++L ++++H I HRDIKLEN++L
Sbjct: 178 DLLRYVQEHGGIHEQKAGLFMSQLIRGLQFMHSINIAHRDIKLENIIL------------ 225
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
N V+L+DFG +K+ + +T CGS+ Y +PE+L G+ Y+ +SD W+ GV
Sbjct: 226 ------FDNCVKLSDFGFVRKMDESALSSTFCGSKSYSAPELLRGIVYNPFLSDVWSLGV 279
Query: 455 ITYALLEDRLPFD 467
+ + ++ +R+PFD
Sbjct: 280 VGFVMVTNRMPFD 292
>CE18366 [T] KOG0583 Serine/threonine protein kinase
Length = 331
Score = 81.3 bits (199), Expect = 4e-15
Identities = 60/205 (29%), Positives = 89/205 (43%), Gaps = 27/205 (13%)
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRI-ITELSVAIKYLHDNFIIHRDIKLENVLL-KYT 385
+ +C GGDL K K + + + A+ +L I+HRD+K EN+ L KY
Sbjct: 114 VTEFCAGGDLLRKMKKIKTMSEENAKFTFRQFIAALMHLQSYNIVHRDLKCENIFLDKY- 172
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
V+L DFG + + P E T CGS YV+PEIL G Y G
Sbjct: 173 -----------------ENVKLGDFGFSRILKPGEKSGTFCGSRAYVAPEILRGREYSGN 215
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIV 505
D W+ GVI Y +L +PFD + R +AH+I K+ K +K ++
Sbjct: 216 AVDVWSTGVILYIMLVGTMPFDD-RDPTRMIERQLAHKI-----KFGKTCTASIHSKALI 269
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
L R +C + +++N
Sbjct: 270 LEILQPHAPNRPTYKAICESEWLKN 294
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 81.3 bits (199), Expect = 4e-15
Identities = 77/329 (23%), Positives = 144/329 (43%), Gaps = 74/329 (22%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
+ +GSG+F+ V+L I+ + + VAVK I+ + + P + R
Sbjct: 29 RRLGSGSFAKVHLARSIESD---------ELVAVKIIEKKKTIESGMEPR-------IIR 72
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ +++R HHP I+K+ + T + +Y ++M +GG
Sbjct: 73 EIDAMRRLR------HHPNILKIHEVMAT-----KSKIY------------LVMELASGG 109
Query: 336 DLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+LF + + ++P R +L+ A+++ H + + HRD+K +N+LL
Sbjct: 110 ELFSKVLRRGRLPESTARRYFQQLASALRFSHQDGVAHRDVKPQNLLL------------ 157
Query: 395 DESQFFSKNFVELADFGLCK--KITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
DE + ++++DFGL + + + T CG+ Y +PE++ YDG +DAW+
Sbjct: 158 DE-----QGNLKVSDFGLSALPEHLQNGLLHTACGTPAYTAPEVISRRGYDGAKADAWSC 212
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWK---WLKNADTDHPAKEIVQNTL 509
GVI + LL +PFD ++ +I R D++ W+ + + N +
Sbjct: 213 GVILFVLLVGDVPFD------DSNIAAMYRKIHRRDYRFPSWISKQAKSIIYQMLDPNPV 266
Query: 510 VRKS------ERWNMDQLCNTPYIRNIID 532
R S W L + + RN+ D
Sbjct: 267 TRMSIETVMKTNWFKKSLETSEFHRNVFD 295
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 81.3 bits (199), Expect = 4e-15
Identities = 75/324 (23%), Positives = 133/324 (40%), Gaps = 73/324 (22%)
Query: 211 QWSKI-----KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPS 265
QWS + +G G F VYL + KY+ + + ++
Sbjct: 16 QWSLADFEIGRPLGKGKFGRVYLAR----------EAKSKYIVALKVIFKEQI------- 58
Query: 266 SPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRC 325
KYK + L+RE+ S+ HP I++LF + D ++
Sbjct: 59 -EKYK-----IHHQLRREMEIQTSLRHPNILRLFG-----WFHDNERIF----------- 96
Query: 326 DMIMSYCTGGDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKY 384
+I+ Y GG+L+ + + + I LS A+ Y H +IHRDIK EN+LL +
Sbjct: 97 -LILEYAHGGELYGVLKQNGHLTEQQAATYIASLSQALAYCHGKCVIHRDIKPENLLLDH 155
Query: 385 TLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDG 444
+ +++ADFG + T CG+ DY++PE++ +D
Sbjct: 156 -----------------EGRLKIADFGW--SVQSSNKRKTMCGTLDYLAPEMVENRDHDY 196
Query: 445 RISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEI 504
+ D W G++ Y L PF+ + + RI + D + + AK +
Sbjct: 197 AV-DNWTLGILCYEFLYGNPPFE------AESQKDTFKRILKIDLSFPLTPNVSEEAKNL 249
Query: 505 VQNTLVR-KSERWNMDQLCNTPYI 527
+ LV+ S+R +++++ P+I
Sbjct: 250 ISQLLVKDPSKRLSIEKIMQHPWI 273
>YCR073c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1331
Score = 80.9 bits (198), Expect = 5e-15
Identities = 73/293 (24%), Positives = 120/293 (40%), Gaps = 78/293 (26%)
Query: 201 MANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINL-NPELKYVAVKSIKYPRELL 259
+A++ +++S +W K IG G F VY INL N E+ +AVK IK
Sbjct: 1023 LASSLSNVSMRWQKRSFIGGGTFGQVYSA--------INLENGEI--LAVKEIKIHDTTT 1072
Query: 260 MSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKL 319
M ++ +K E+T L ++HP IV+ + + R K+
Sbjct: 1073 MK-------------KIFPLIKEEMTVLEMLNHPNIVQYYGVE-----------VHRDKV 1108
Query: 320 SALPRCDMIMSYCTGGDLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLE 378
+ + M YC GG L L +I + ++T++ T EL + YLH + ++HRDIK E
Sbjct: 1109 N------IFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPE 1162
Query: 379 NVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTR------------- 425
N+LL + ++ DFG + + T R
Sbjct: 1163 NILLDF-----------------NGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKS 1205
Query: 426 ----CGSEDYVSPEILLGLPYDGRI--SDAWAFGVITYALLEDRLPFDPLPGQ 472
G+ Y++PE + G G++ D WA G + + R P+ L +
Sbjct: 1206 LNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNE 1258
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 80.9 bits (198), Expect = 5e-15
Identities = 54/160 (33%), Positives = 79/160 (48%), Gaps = 22/160 (13%)
Query: 311 HPLYGRRKLS--ALPRCDMIMSYCTGGDLFDLASKTKIPNWLLTRII-TELSVAIKYLHD 367
HP K S R +M Y GG+LF S+ ++ + TR E+ A+ YLH
Sbjct: 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 368 NFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRC 426
I++RD+KLEN++L +++ DFGLCK+ IT T C
Sbjct: 265 GKIVYRDLKLENLMLD-----------------KDGHIKITDFGLCKEGITDAATMKTFC 307
Query: 427 GSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
G+ +Y++PE+L Y GR D W GV+ Y ++ RLPF
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPF 346
>CE02604 [T] KOG0695 Serine/threonine protein kinase
Length = 597
Score = 80.9 bits (198), Expect = 5e-15
Identities = 49/153 (32%), Positives = 83/153 (54%), Gaps = 20/153 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R ++ + GGDL F + + K+P E+ +A+ +LH II+RD+KL+NVL+
Sbjct: 326 RLFFVIEFVPGGDLMFHMQQQRKLPEEHARFYSGEIILALHFLHSRGIIYRDLKLDNVLI 385
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
++ ++L D+G+CK+ I ++ +T CG+ +Y++PEIL G
Sbjct: 386 D-----------------AEGHIKLTDYGMCKENIKDGDLTSTFCGTPNYIAPEILRGDE 428
Query: 442 YDGRISDAWAFGVITYALLEDRLPFDPLPGQSS 474
Y G D WA GV+ + ++ R PFD + Q+S
Sbjct: 429 Y-GFSVDWWALGVLMFEMMAGRSPFDIVGMQNS 460
>7296128 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 80.9 bits (198), Expect = 5e-15
Identities = 79/321 (24%), Positives = 134/321 (41%), Gaps = 78/321 (24%)
Query: 217 EIGSGNFSTVYL--YECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+IG GNFS V L ++ D VA+K + R L +
Sbjct: 49 DIGRGNFSKVKLAVHQLTRDK-----------VAIKVVDLDRA-------------GLDA 84
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
+ + L E+ TL VHHP I++LF + +T L R ++ + G
Sbjct: 85 KALRMLSSEIATLECVHHPNILRLFEVVET-----------------LGRVYLVTEWIRG 127
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+L++ + + ++ +L +A+K++H +HRDIK ENVLL L
Sbjct: 128 GELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLL---------LS 178
Query: 394 EDESQFFSKNFVELADFGLCKKIT----PDEMCTTRCGSEDYVSPEILLGLPYDGRISDA 449
ED ++LADFG ++ ++ T CGS Y +PE+ Y G D
Sbjct: 179 EDR--------LKLADFGFSTQLINGTGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDV 230
Query: 450 WAFGVITYALLEDRLPF--DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQN 507
WA G++ Y ++ +PF +PG + A +L P ++Q
Sbjct: 231 WALGILLYFMVVGNMPFRAPTIPGL----------KAAILKGDYLLPGQLSLPCIRLIQR 280
Query: 508 TLVR-KSERWNMDQLCNTPYI 527
L+ ++R +D + N+ ++
Sbjct: 281 ILIHIPAQRPTIDDMLNSQFV 301
>YPL150w [T] KOG0583 Serine/threonine protein kinase
Length = 901
Score = 80.5 bits (197), Expect = 6e-15
Identities = 55/204 (26%), Positives = 93/204 (44%), Gaps = 26/204 (12%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
M + YC G +L+D L S +I + ++S A+ Y H +HRD+KLEN+LL
Sbjct: 109 MALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLD-- 166
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+L DFG ++ T CG+ Y++PE++ YDG
Sbjct: 167 ---------------KNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGF 211
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIV 505
D W+ GVI Y L+ LPFD ++ I + + D K + + A++++
Sbjct: 212 KIDIWSLGVILYTLITGYLPFD--DDDEAKTKWKIVNEEPKYDAKVIPD-----DARDLI 264
Query: 506 QNTLVRK-SERWNMDQLCNTPYIR 528
L + ER ++ Q+ P+++
Sbjct: 265 SRLLAKNPGERPSLSQVLRHPFLQ 288
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 80.5 bits (197), Expect = 6e-15
Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 46/255 (18%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
V L+RE+ +HHP I++L+ + Y RR++ +I+ Y G
Sbjct: 118 VEHQLRREIEIQAHLHHPNILRLY-----------NYFYDRRRIY------LILEYAPRG 160
Query: 336 DLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+L+ +L I+ EL+ A+ Y H +IHRDIK EN+LL
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGL---------- 210
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
K +++ADFG P T CG+ DY+ PE++ G ++ ++ D W GV
Sbjct: 211 -------KGELKIADFGWSVH-APSLRRKTMCGTLDYLPPEMIEGRMHNEKV-DLWCIGV 261
Query: 455 ITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK-S 513
+ Y LL PF+ + R RI + D K+ + T A++++ L S
Sbjct: 262 LCYELLVGNPPFESASHNETYR------RIVKVDLKFPASVPTG--AQDLISKLLRHNPS 313
Query: 514 ERWNMDQLCNTPYIR 528
ER + Q+ P++R
Sbjct: 314 ERLPLAQVSAHPWVR 328
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 80.5 bits (197), Expect = 6e-15
Identities = 58/189 (30%), Positives = 89/189 (46%), Gaps = 37/189 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF- 338
L+RE+ + HP I++L+ + D +Y +I+ Y G+L+
Sbjct: 54 LRREIEIQAHLQHPNILRLY-----NYFHDARRVY------------LILEYAPRGELYK 96
Query: 339 DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+L K+ II E++ A+ Y HD +IHRDIK EN+LL +
Sbjct: 97 ELQKSEKLDEQRTATIIEEVADALTYCHDKKVIHRDIKPENLLLGF-------------- 142
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+ V++ADFG TP T CG+ DY+ PE++ G YD ++ D W GV+ Y
Sbjct: 143 ---RGEVKIADFGWSVH-TPLPERKTMCGTLDYLPPEMIEGRTYDEKV-DLWCIGVLCYE 197
Query: 459 LLEDRLPFD 467
LL PF+
Sbjct: 198 LLVGYPPFE 206
>Hs14777335 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 795
Score = 80.5 bits (197), Expect = 6e-15
Identities = 63/216 (29%), Positives = 103/216 (47%), Gaps = 37/216 (17%)
Query: 325 CDMIMSYCTGGDLFDLASK-----TKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLEN 379
C ++M Y GG+LFD + T++ L TR I E + YLH ++I+H D+K EN
Sbjct: 561 CTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICE---GVHYLHQHYILHLDLKPEN 617
Query: 380 VLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLG 439
+L + + Q +++ DFGL ++ P E G+ ++++PE+ +
Sbjct: 618 IL---------CVNQTGHQ------IKIIDFGLARRYKPREKLKVNFGTPEFLAPEV-VN 661
Query: 440 LPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADT-- 497
+ +D W+ GVITY LL PF G++ T + I C W + +ADT
Sbjct: 662 YEFVSFPTDMWSVGVITYMLLSGLSPF---LGETDAETMNF---IVNCSWDF--DADTFE 713
Query: 498 --DHPAKEIVQNTLVR-KSERWNMDQLCNTPYIRNI 530
AK+ V LV+ KS R + Q ++ N+
Sbjct: 714 GLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNL 749
>CE21879 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 328
Score = 80.5 bits (197), Expect = 6e-15
Identities = 77/326 (23%), Positives = 148/326 (44%), Gaps = 68/326 (20%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
Q+ IK IG G F V+L E ++ NP +K VA+K I + +P K
Sbjct: 5 QFKPIKSIGKGAFGQVFLAEKLN-------NPRIK-VAMKKIN------IFGAP-----K 45
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAIN-DTTFITDEHPLYGRRKLSALPRCDMIM 329
E L ++ ++E ++ H IVK++ ++ DT F C +
Sbjct: 46 EFLEQI----QQEYYIQKNMKHKNIVKMYGMSMDTEF------------------CYLFQ 83
Query: 330 SYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
+ TGGDLF+ + + +P + + +L +KY+H I+HRDIK +N+L+
Sbjct: 84 EFVTGGDLFEKIDFENGMPVNQVKGYLKQLMSGLKYIHGCGIVHRDIKPDNLLIN----- 138
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDE---MCTTRCGSEDYVSPEILLGLPYDGR 445
S + +++ADFGL + D+ + R G+ +++PE+ + G
Sbjct: 139 ------------SSDALKIADFGLSTRFIVDDKEILLHERIGTTPFMAPELFAKKKHRGP 186
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIAR-CDWKWLKNADTDHPAKEI 504
D W+ G++ ++LL LP+D ++ + ++ ++ C W L K +
Sbjct: 187 PVDIWSAGILVFSLLTGNLPWDEPKESDILYSQWMNNKTSKNCIWYGLSTPVVRFLKKLL 246
Query: 505 VQNTLVRKSERWNMDQLCNTPYIRNI 530
+N +ER ++++ + P++ ++
Sbjct: 247 KENV----NERATIEEIESDPWLEDL 268
>CE12518 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 391
Score = 80.5 bits (197), Expect = 6e-15
Identities = 52/191 (27%), Positives = 90/191 (46%), Gaps = 34/191 (17%)
Query: 279 SLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF 338
++ EL L + HP +++L + + + ++M +GG+++
Sbjct: 108 AVNNELNILSRLSHPFVIRLEEV-----------------FKSSSKLFIVMQMASGGEMY 150
Query: 339 D-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
D + +K + + L + YLH + HRD+K EN+L + + LL
Sbjct: 151 DRVVAKGRYSEEEARNALKMLLTGLTYLHSIRVTHRDLKPENLLYADSRPEARLL----- 205
Query: 398 QFFSKNFVELADFGLCKKIT-PDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVIT 456
+ DFGL + T P+E T CG+ +Y++PE+LL +PY ++ D WA GVI
Sbjct: 206 ---------ITDFGLAYQATKPNETMTETCGTPEYIAPELLLRVPYTQKV-DMWAVGVIA 255
Query: 457 YALLEDRLPFD 467
Y L+ +PFD
Sbjct: 256 YILMSGIMPFD 266
>SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase
Length = 532
Score = 80.1 bits (196), Expect = 8e-15
Identities = 52/189 (27%), Positives = 83/189 (43%), Gaps = 36/189 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
L+RE+T L +HHP I+ L+ + +P+ ++ DL
Sbjct: 68 LQREVTILRQLHHPNIITLYQV------------------FRVPKYTVLALEYMDTDLHS 109
Query: 340 LASK-TKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ K ++ +I ++ AI Y H + + HRD+KLEN+LL L
Sbjct: 110 MVVKHNRLDECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDL------------ 157
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
V+L DFGL + +T CG+ Y +PE++ G YDG D W G++ Y
Sbjct: 158 -----VVKLTDFGLSNFMLDGSFLSTSCGTPHYAAPEVIQGRYYDGCDVDVWGCGILLYL 212
Query: 459 LLEDRLPFD 467
+L PF+
Sbjct: 213 MLVGEFPFE 221
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 80.1 bits (196), Expect = 8e-15
Identities = 83/362 (22%), Positives = 146/362 (39%), Gaps = 81/362 (22%)
Query: 107 HEEVLDEELSKLGTYMNRDVTHKIKGRMLSEYIPNNSMGDGSGGVAVQRSISLNNRVVEK 166
H++ LS G Y N I +L E + S+GD +G N VE
Sbjct: 20 HQQPTLNVLSPWGAYFNH-----IGNELLKENSNDKSVGDKNGNTTT------NKTTVEP 68
Query: 167 PSLKKETIINEVITSVPSDKENEQKADGTIIRGY--MANTPNHISFQWSKIKEIGSGNFS 224
P ++ + E+ +D ++ + N N + ++ K+IG G
Sbjct: 69 PPPEEPPVRVRA-------SHREKLSDSEVLNQLREIVNPSNPLG-KYEMKKQIGVGASG 120
Query: 225 TVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKREL 284
TV++ N+ VAVK + + + PK + LL+ E+
Sbjct: 121 TVFV---------ANVAGSTDVVAVKRMAFKTQ---------PKKEMLLT--------EI 154
Query: 285 TTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLASKT 344
+ HP +V +++ D L+ ++M Y GG+L D+ KT
Sbjct: 155 KVMKQYRHPNLVNYIE----SYLVDADDLW------------VVMDYLEGGNLTDVVVKT 198
Query: 345 KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNF 404
++ + ++ E A+ +LH + I+HRDIK +NVLL +
Sbjct: 199 ELDEGQIAAVLQECLKALHFLHRHSIVHRDIKSDNVLLGMNGE----------------- 241
Query: 405 VELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRL 464
V+L D G C +I P T G+ ++SPEIL Y+ ++ D W+ G++ +++
Sbjct: 242 VKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKV-DIWSLGIMALEMIDGEP 300
Query: 465 PF 466
P+
Sbjct: 301 PY 302
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 80.1 bits (196), Expect = 8e-15
Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 37/202 (18%)
Query: 268 KYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
K K + +V +KRE++ + V HP IV+L + +++ +
Sbjct: 57 KEKVVKVGMVDQIKREISVMRMVKHPNIVELHEV-----------------MASKSKIYF 99
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
M GG+LF +K ++ + +L A+ + H + HRD+K EN+LL
Sbjct: 100 AMELVRGGELFAKVAKGRLREDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLL----- 154
Query: 388 DMMLLKEDESQFFSKNFVELADFGLC---KKITPDEMCTTRCGSEDYVSPEILLGLPYDG 444
DE + +++ DFGL + + D + T CG+ YV+PE++L YDG
Sbjct: 155 -------DE-----EGNLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDG 202
Query: 445 RISDAWAFGVITYALLEDRLPF 466
+D W+ GVI + LL LPF
Sbjct: 203 AKADLWSCGVILFVLLAGYLPF 224
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 79.7 bits (195), Expect = 1e-14
Identities = 74/284 (26%), Positives = 117/284 (41%), Gaps = 65/284 (22%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
K++G G F VY C+ Y+ + E++ KY
Sbjct: 108 KKLGKGKFGKVY---CVRHR-------STGYICALKVMEKEEII--------KYN----- 144
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ +RE+ S++HP + K + + DE +Y ++M Y G
Sbjct: 145 LQKQFRREVEIQTSLNHPNLTKSYG-----YFHDEKRVY------------LLMEYLVNG 187
Query: 336 DLFDLASKTKIPNWLLTR-IITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+++ L N +L I +++ A+ Y+H IIHRDIK EN+L+ +
Sbjct: 188 EMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGF---------- 237
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
N ++L DFG P+ T CG+ DY+SPE++ YD I DAWA GV
Sbjct: 238 -------NNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTI-DAWALGV 289
Query: 455 ITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTD 498
+ + LL PF+ ++ + RIA D K N D
Sbjct: 290 LAFELLTGAPPFEEEMKDTTYK------RIAALDIKMPSNISQD 327
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 79.7 bits (195), Expect = 1e-14
Identities = 67/253 (26%), Positives = 116/253 (45%), Gaps = 60/253 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
++ +G+G+F V+L + + L Y A+K ++ + + M + + +LS
Sbjct: 204 LQTLGTGSFGRVHLVQSNHNRL---------YYAIKVLEKKKIVDMKQIEHTCDERYILS 254
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
RV HP I L+ TF D L+ M+M + G
Sbjct: 255 RV--------------QHPFITILWG----TF-QDAKNLF------------MVMDFAEG 283
Query: 335 GDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LF L K + P + E+ +A+ YLH N I++RD+K EN+LL
Sbjct: 284 GELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLL----------- 332
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+F +++ DFG K+++ CT CG+ DY++PEI+ PY+ + +D W+ G
Sbjct: 333 ---DRF---GHLKIVDFGFAKRVSTSNCCTL-CGTPDYLAPEIISLKPYN-KAADWWSLG 384
Query: 454 VITYALLEDRLPF 466
++ + +L PF
Sbjct: 385 ILIFEMLAGYPPF 397
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 79.7 bits (195), Expect = 1e-14
Identities = 63/202 (31%), Positives = 94/202 (46%), Gaps = 37/202 (18%)
Query: 270 KELLSRVVSSLKRELTTL--ISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
K+++ + +K E+ L +S HP I+ L +T + LY +
Sbjct: 64 KKMMEKKQDFVKNEIAILKRVSYEHPNILHLVDFFETV-----NNLY------------L 106
Query: 328 IMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
I TGG+LFD + +K ++ + A+KYLHDN I+HRD+K EN+L +
Sbjct: 107 ITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKD 166
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDE--MCTTRCGSEDYVSPEILLGLPYDG 444
+ LL +ADFGL + M T CG+ +Y++PE+ Y G
Sbjct: 167 PNSDLL--------------IADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGY-G 211
Query: 445 RISDAWAFGVITYALLEDRLPF 466
+ D WA GVITY LL PF
Sbjct: 212 KPVDMWAIGVITYFLLSGYTPF 233
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 79.7 bits (195), Expect = 1e-14
Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 20/146 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R +M Y GGDL F + K E++ A+ +LH + +I+RD+KL+N+LL
Sbjct: 481 RLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILL 540
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
++ +LADFG+CK+ I TT CG+ DY++PEIL L
Sbjct: 541 D-----------------AEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELE 583
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G D WA GV+ Y ++ + PF+
Sbjct: 584 Y-GPSVDWWALGVLMYEMMAGQPPFE 608
>Hs4759044 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 79.7 bits (195), Expect = 1e-14
Identities = 62/213 (29%), Positives = 99/213 (46%), Gaps = 33/213 (15%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
M+M Y GGDL +L S +P E+ +A+ +H +IHRD+K +N+LL
Sbjct: 167 MVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLD--- 223
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM--CTTRCGSEDYVSPEILL---GLP 441
++LADFG C K+ M C T G+ DY+SPE+L G
Sbjct: 224 --------------KHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
Query: 442 YDGRISDAWAFGVITYALLEDRLPF--DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDH 499
+ GR D W+ GV Y +L PF D L G S + + H+ + C + ++A+
Sbjct: 270 FYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYS---KIMDHKNSLC---FPEDAEISK 323
Query: 500 PAKEIVQNTLVRKSERW---NMDQLCNTPYIRN 529
AK ++ L + R ++++ P+ +N
Sbjct: 324 HAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN 356
>Hs20536595 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1388
Score = 79.7 bits (195), Expect = 1e-14
Identities = 62/213 (29%), Positives = 99/213 (46%), Gaps = 33/213 (15%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
M+M Y GGDL +L S +P E+ +A+ +H +IHRD+K +N+LL
Sbjct: 167 MVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLD--- 223
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDEM--CTTRCGSEDYVSPEILL---GLP 441
++LADFG C K+ M C T G+ DY+SPE+L G
Sbjct: 224 --------------KHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDG 269
Query: 442 YDGRISDAWAFGVITYALLEDRLPF--DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDH 499
+ GR D W+ GV Y +L PF D L G S + + H+ + C + ++A+
Sbjct: 270 FYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYS---KIMDHKNSLC---FPEDAEISK 323
Query: 500 PAKEIVQNTLVRKSERW---NMDQLCNTPYIRN 529
AK ++ L + R ++++ P+ +N
Sbjct: 324 HAKNLICAFLTDREVRLGRNGVEEIRQHPFFKN 356
>7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 405
Score = 79.7 bits (195), Expect = 1e-14
Identities = 49/141 (34%), Positives = 76/141 (53%), Gaps = 17/141 (12%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M TGG+LFD + K + +I ++ A+ Y+H+ ++HRD+K EN LL Y+
Sbjct: 120 LVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPEN-LLYYS 178
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
DD + + ++DFGL K+ + T CG+ YV+PE+L PY G+
Sbjct: 179 PDD-------------DSKIMISDFGL-SKMEDSGIMATACGTPGYVAPEVLAQKPY-GK 223
Query: 446 ISDAWAFGVITYALLEDRLPF 466
D W+ GVI+Y LL PF
Sbjct: 224 AVDVWSIGVISYILLCGYPPF 244
>At3g50500 [T] KOG0583 Serine/threonine protein kinase
Length = 362
Score = 79.3 bits (194), Expect = 1e-14
Identities = 71/273 (26%), Positives = 113/273 (41%), Gaps = 61/273 (22%)
Query: 207 HISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSS 266
H S ++ +K+IGSGNF L + D + L VAV
Sbjct: 18 HDSDRYDFVKDIGSGNFGVARL---MTDRVTKEL------VAV----------------- 51
Query: 267 PKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCD 326
KY E ++ +++RE+ S+ HP IV+ + +T H
Sbjct: 52 -KYIERGEKIDENVQREIINHRSLRHPNIVRFKEV----ILTPSH-------------LA 93
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M Y GG+L++ + + + +L + Y H I HRD+KLEN LL +
Sbjct: 94 IVMEYAAGGELYERICNAGRFSEDEARFFFQQLISGVSYCHAMQICHRDLKLENTLLDGS 153
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+ ++ DFG K + G+ Y++PEILL YDG+
Sbjct: 154 PAPRL---------------KICDFGYSKSSVLHSQPKSTVGTPAYIAPEILLRQEYDGK 198
Query: 446 ISDAWAFGVITYALLEDRLPF-DPLPGQSSRRT 477
++D W+ GV Y +L PF DP + R+T
Sbjct: 199 LADVWSCGVTLYVMLVGAYPFEDPQEPRDYRKT 231
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 79.3 bits (194), Expect = 1e-14
Identities = 48/146 (32%), Positives = 76/146 (51%), Gaps = 20/146 (13%)
Query: 324 RCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
R +M Y GGDL F + + E+++A+++LH + +I+RD+KL+N+LL
Sbjct: 481 RLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILL 540
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
+ +LADFG+CK+ I + TT CG+ DY++PEIL
Sbjct: 541 D-----------------QEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQE 583
Query: 442 YDGRISDAWAFGVITYALLEDRLPFD 467
Y G D WA GV+ Y ++ + PF+
Sbjct: 584 Y-GASVDWWALGVLMYEMMAGQPPFE 608
>SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 436
Score = 79.0 bits (193), Expect = 2e-14
Identities = 59/196 (30%), Positives = 90/196 (45%), Gaps = 36/196 (18%)
Query: 272 LLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSY 331
L ++ + K E L V HP I +L+ D LY +I+ Y
Sbjct: 129 LRAKGLEQTKNERQILEEVRHPFICRLYYA-----FQDHDRLY------------LILQY 171
Query: 332 CTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMM 390
GG+LF LA + +P ++ EL++A+ +LH I++RD+K EN LL
Sbjct: 172 APGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLHKLGIVYRDLKPENCLLD------- 224
Query: 391 LLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAW 450
++ + L DFGL K C + G+E+Y +PEILL PYD + D W
Sbjct: 225 ----------AEGHILLTDFGLSKVAENGADCRSFVGTEEYCAPEILLEQPYDHAV-DWW 273
Query: 451 AFGVITYALLEDRLPF 466
+ G++ + LL PF
Sbjct: 274 SMGILIFDLLTGSPPF 289
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 79.0 bits (193), Expect = 2e-14
Identities = 48/145 (33%), Positives = 74/145 (50%), Gaps = 20/145 (13%)
Query: 324 RCDMIMSYCTGGDLFDLASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLL 382
R +M Y GG+LF S+ ++ R E+ A++YLH +++RDIKLEN++L
Sbjct: 224 RLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLML 283
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLP 441
+++ DFGLCK+ I+ T CG+ +Y++PE+L
Sbjct: 284 D-----------------KDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND 326
Query: 442 YDGRISDAWAFGVITYALLEDRLPF 466
Y GR D W GV+ Y ++ RLPF
Sbjct: 327 Y-GRAVDWWGLGVVMYEMMCGRLPF 350
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 78.6 bits (192), Expect = 2e-14
Identities = 68/253 (26%), Positives = 118/253 (45%), Gaps = 37/253 (14%)
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
S L+ E+ L ++HHP +V L + F T E KL +MI+S
Sbjct: 625 SQLRNEVAILQNLHHPGVVNL----ECMFETPERVFVVMEKLHG-DMLEMILS------- 672
Query: 338 FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ K ++P + +IT++ VA+++LH I+H D+K ENVLL +
Sbjct: 673 ---SEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLA------------SA 717
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
F + V+L DFG + I + G+ Y++PE+L Y+ R D W+ GVI Y
Sbjct: 718 DPFPQ--VKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYN-RSLDMWSVGVIIY 774
Query: 458 ALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTL-VRKSERW 516
L PF+ + ++ A WK + H A +++ N L V+ +R+
Sbjct: 775 VSLSGTFPFNE-DEDIHDQIQNAAFMYPPNPWK-----EISHEAIDLINNLLQVKMRKRY 828
Query: 517 NMDQLCNTPYIRN 529
++D+ + P++++
Sbjct: 829 SVDKTLSHPWLQD 841
>CE17343 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 78.6 bits (192), Expect = 2e-14
Identities = 51/162 (31%), Positives = 73/162 (44%), Gaps = 27/162 (16%)
Query: 328 IMSYCTGGDLFD-----LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
+ YC GGDL +A K + + ++I A+ +L I+HRD+K EN+ +
Sbjct: 147 VNEYCAGGDLLRKMKDIVAMKEEDAKFTFRQLIA----ALTHLQSYNIVHRDLKCENIFM 202
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPY 442
V+L DFG + + P E T CGS YV+PEI G Y
Sbjct: 203 D-----------------KHGNVKLGDFGFSRILKPGEKSGTFCGSRAYVAPEIFRGREY 245
Query: 443 DGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRI 484
G D W+ GVI Y +L +PFD + R +AH+I
Sbjct: 246 SGNAVDVWSTGVILYIMLAGSMPFDDRDPRKMIE-RQLAHKI 286
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 78.6 bits (192), Expect = 2e-14
Identities = 45/130 (34%), Positives = 71/130 (54%), Gaps = 21/130 (16%)
Query: 327 MIMSYCTGGDLFDLASKTK---IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLK 383
++ SYC GGD+ + K++ L R + +L +AI YLH+N ++HRD+K N+ L
Sbjct: 89 IVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLT 148
Query: 384 YTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYD 443
KE+E V L DFGL K + D++ ++ G+ +Y+ PE+L +PY
Sbjct: 149 ---------KENE--------VRLGDFGLAKLLGKDDLASSMVGTPNYMCPELLADIPY- 190
Query: 444 GRISDAWAFG 453
G SD W+ G
Sbjct: 191 GYKSDIWSLG 200
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 78.6 bits (192), Expect = 2e-14
Identities = 62/189 (32%), Positives = 86/189 (44%), Gaps = 43/189 (22%)
Query: 283 ELTTLISVHHPCIVKL---FAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
E L S +HP ++ L F ND R +M Y GG+LF
Sbjct: 233 ESRVLKSTNHPFLISLKYSFQTND--------------------RLCFVMQYVNGGELFW 272
Query: 340 LASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
S +I TR E+ A+ YLH II+RD+KLEN+LL
Sbjct: 273 HLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLD--------------- 317
Query: 399 FFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
+++ADFGLCK+ IT T CG+ +Y++PE+L Y G+ D W GV+ Y
Sbjct: 318 --KDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDY-GQAVDWWGTGVVMY 374
Query: 458 ALLEDRLPF 466
++ RLPF
Sbjct: 375 EMICGRLPF 383
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 78.2 bits (191), Expect = 3e-14
Identities = 42/142 (29%), Positives = 70/142 (48%), Gaps = 18/142 (12%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
M+ Y +GG L D + + + ++ A++YLH N I+HRD+K+EN+++
Sbjct: 200 MLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMIS-- 257
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
S +++ DFGL + T CGS + +PE+L PY G
Sbjct: 258 ---------------SSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGP 302
Query: 446 ISDAWAFGVITYALLEDRLPFD 467
D W+FG++ Y L+ ++PFD
Sbjct: 303 EVDIWSFGIVLYVLVCGKVPFD 324
>Hs19923134 [T] KOG4250 TANK binding protein kinase TBK1
Length = 745
Score = 78.2 bits (191), Expect = 3e-14
Identities = 64/260 (24%), Positives = 114/260 (43%), Gaps = 58/260 (22%)
Query: 212 WSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKE 271
W + +G+G F V LY+ + +L I A+KS + EL S K +E
Sbjct: 15 WEMRERLGTGGFGNVCLYQHRELDLKI---------AIKSCRL--EL-------STKNRE 56
Query: 272 LLSRVVSSLKRELTTLISVHHPCIVKLFAI-NDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+ +K+ ++H +VK + + + + PL + M
Sbjct: 57 RWCHEIQIMKK-------LNHANVVKACDVPEELNILIHDVPL-------------LAME 96
Query: 331 YCTGGDLFDLASKTK----IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
YC+GGDL L +K + + + +++++ I+YLH+N IIHRD+K EN++L+
Sbjct: 97 YCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQ--- 153
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRI 446
K ++ D G K + +CT+ G+ Y++PE+ PY +
Sbjct: 154 -----------DVGGKIIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATV 202
Query: 447 SDAWAFGVITYALLEDRLPF 466
D W+FG + + + PF
Sbjct: 203 -DYWSFGTMVFECIAGYRPF 221
>CE27670 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 572
Score = 78.2 bits (191), Expect = 3e-14
Identities = 53/217 (24%), Positives = 99/217 (45%), Gaps = 44/217 (20%)
Query: 325 CD---MIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVL 381
CD ++M Y GG L D+ ++ ++ + ++ + E+ A+++LH +IHRDIK +N+L
Sbjct: 362 CDELWVVMEYLAGGSLTDVVTECQMEDGIIAAVCREVLQALEFLHSRHVIHRDIKSDNIL 421
Query: 382 LKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDE-MCTTRCGSEDYVSPEILLGL 440
L V+L DFG C +++P++ TT G+ +++PE++
Sbjct: 422 LG-----------------MDGSVKLTDFGFCAQLSPEQRKRTTMVGTPYWMAPEVVTRK 464
Query: 441 PYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP 500
Y ++ D W+ G++ ++E P+ + R + N D P
Sbjct: 465 QYGPKV-DVWSLGIMAIEMVEGEPPY-------------LNENPLRAIYLIATNGKPDFP 510
Query: 501 A--------KEIVQNTL-VRKSERWNMDQLCNTPYIR 528
K+ V + L V+ RW+ QL P++R
Sbjct: 511 GRDSMTLLFKDFVDSALEVQVENRWSASQLLTHPFLR 547
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 78.2 bits (191), Expect = 3e-14
Identities = 84/263 (31%), Positives = 119/263 (44%), Gaps = 59/263 (22%)
Query: 205 PNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSP 264
P I+ ++ + IG GNF+ V EC++ + + A+K IK
Sbjct: 39 PATITERYKVGRTIGDGNFAVVK--ECVERST-------AREYALKIIK----------K 79
Query: 265 SSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPR 324
S + KE + ++ E++ L V HP IV L D LY
Sbjct: 80 SKCRGKEHM------IQNEVSILRRVKHPNIVLLIEEMDVPT-----ELY---------- 118
Query: 325 CDMIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLK 383
++M GGDLFD + S K + ++ L+ AIKYLH I+HRDIK EN+L+
Sbjct: 119 --LVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVY 176
Query: 384 YTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYD 443
E Q SK+ ++L DFGL + D T CG+ YV+PEI+ Y
Sbjct: 177 ------------EHQDGSKS-LKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGYG 221
Query: 444 GRISDAWAFGVITYALLEDRLPF 466
++ D WA GVITY LL PF
Sbjct: 222 LKV-DIWAAGVITYILLCGFPPF 243
>YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 446
Score = 77.8 bits (190), Expect = 4e-14
Identities = 79/282 (28%), Positives = 120/282 (42%), Gaps = 64/282 (22%)
Query: 184 SDKENEQKADGTIIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPE 243
S K+ E+ ++G + A+ N + + K +G+G F V + N +
Sbjct: 11 SPKQTEEDSEGKMAHVQPASYVNKKKYVFGKT--LGAGTFGVVRQAK----NTETGEDVA 64
Query: 244 LKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKL---FA 300
+K + K++K + L +L EL L +HHP IV F
Sbjct: 65 VKILIKKALKGNKVQL------------------EALYDELDILQRLHHPNIVAFKDWFE 106
Query: 301 INDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD-LASKTKIPNWLLTRIITELS 359
D +I I GG+LFD + K K RI+ E+
Sbjct: 107 SKDKFYI--------------------ITQLAKGGELFDRILKKGKFTEEDAVRILVEIL 146
Query: 360 VAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPD 419
A+KY+H I+HRD+K EN+L + K DES + +ADFG+ K++ D
Sbjct: 147 SAVKYMHSQNIVHRDLKPENLL--------YIDKSDESP------LVVADFGIAKRLKSD 192
Query: 420 -EMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALL 460
E+ GS YV+PE+L + G+ D W+ GVITY LL
Sbjct: 193 EELLYKPAGSLGYVAPEVLTQDGH-GKPCDIWSIGVITYTLL 233
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 77.8 bits (190), Expect = 4e-14
Identities = 86/339 (25%), Positives = 153/339 (44%), Gaps = 62/339 (18%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
Q++ ++++G G FS VY + I + + VA+K ++ + ++ P P+ +
Sbjct: 123 QYTLLQKMGDGAFSNVY--KAIHNRTG-------EKVAIKVVQRAQP---NTDPRDPRKR 170
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+ + ++ +E+ + V HP I++L FI Y +++
Sbjct: 171 QGVES--HNILKEVQIMRRVKHPNIIQLLE-----FIQTPEYYY------------LVLE 211
Query: 331 YCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNF-IIHRDIKLENVLL------ 382
GG+LF + T L +IT+++ AI+YLH++ ++HRDIK EN+L
Sbjct: 212 LADGGELFHQIVRLTYFSEDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLLFDSIDFV 271
Query: 383 -----KYTLDDMMLLKEDESQFF------SKNFVELADFGLCKKITPDEMCTTRCGSEDY 431
KY D K DE +F + + LADFGL K+ D T CG+ Y
Sbjct: 272 PSRVRKYRAGDDP-DKVDEGEFIPGVGAGTIGRIRLADFGL-SKVVWDSHTQTPCGTMGY 329
Query: 432 VSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKW 491
+PEI+ Y + D WA G + Y +L F P +S + +++R ++ +
Sbjct: 330 TAPEIVRDERYSKGV-DMWALGCVLYTIL---CGFPPFYDES---ISLLTKKVSRGEYSF 382
Query: 492 LKN--ADTDHPAKEIVQNTL-VRKSERWNMDQLCNTPYI 527
L D AK+++ + L V R+++ Q P+I
Sbjct: 383 LSPWWDDISKSAKDLISHLLTVDPESRYDIHQFLAHPWI 421
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 77.8 bits (190), Expect = 4e-14
Identities = 63/199 (31%), Positives = 94/199 (46%), Gaps = 39/199 (19%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
V +L+RE + HP I +L I +T E+ Y ++M C GG
Sbjct: 104 VTKNLRREGQIQQMIRHPNITQLLDILET-----ENSYY------------LVMELCPGG 146
Query: 336 DLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+L + K ++ R I +L A+++LH ++HRD+K+EN +LL E
Sbjct: 147 NLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIEN----------LLLDE 196
Query: 395 DESQFFSKNFVELADFGL--CKKITP-DEMCTTRCGSEDYVSPEILLGLPYDGRISDAWA 451
D N ++L DFGL C I + +T+CGS Y +PE+L Y +I D W+
Sbjct: 197 D-------NNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKI-DVWS 248
Query: 452 FGVITYALLEDRLPFDPLP 470
GV YA+L LPF P
Sbjct: 249 IGVNMYAMLTGTLPFTVEP 267
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 77.8 bits (190), Expect = 4e-14
Identities = 79/315 (25%), Positives = 130/315 (41%), Gaps = 77/315 (24%)
Query: 156 SISLNNRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMANTPNHISFQ-WSK 214
+IS +++V + +L+++ KE+ ++ +G + N+ N + +
Sbjct: 314 NISPTSKLVSRSTLRRQ------------GKESSKEGNGIGV-----NSSNRLGIDNFEF 356
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
I+ +G G+F V L + AVK +K LL + K +LS
Sbjct: 357 IRVLGKGSFGKVMLARVKETG---------DLYAVKVLKKDVILLDDDVECTMTEKRILS 407
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
++ +HP + +LF T R +M + G
Sbjct: 408 -------------LARNHPFLTQLFCCFQTP-----------------DRLFFVMEFVNG 437
Query: 335 GDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
GDL F + + E+ A+ +LHD II+RD+KL+NVLL +
Sbjct: 438 GDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDH--------- 488
Query: 394 EDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
+ +LADFG+CK+ I T CG+ DY++PEIL + Y G D WA
Sbjct: 489 --------EGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY-GPAVDWWAM 539
Query: 453 GVITYALLEDRLPFD 467
GV+ Y +L PF+
Sbjct: 540 GVLLYEMLCGHAPFE 554
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 77.8 bits (190), Expect = 4e-14
Identities = 83/308 (26%), Positives = 143/308 (45%), Gaps = 80/308 (25%)
Query: 161 NRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMANTPNHISFQWSKIKEIGS 220
N E+ S+K+ I + V KE +KAD + Q+ +K +G
Sbjct: 39 NPQTEEVSIKEIAITHHV-------KEGHEKADPS---------------QFELLKVLGQ 76
Query: 221 GNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSL 280
G+F V+L + I+ + + A+K +K ++ K ++ RV + +
Sbjct: 77 GSFGKVFLVK------KISGSDARQLYAMKVLK----------KATLKVRD---RVRTKM 117
Query: 281 KRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDL 340
+R++ L+ V+HP IVKL T E LY +I+ + GGDLF
Sbjct: 118 ERDI--LVEVNHPFIVKLHYAFQT-----EGKLY------------LILDFLRGGDLFTR 158
Query: 341 ASK-TKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQF 399
SK + + EL++A+ +LH II+RD+K EN+LL DE
Sbjct: 159 LSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILL------------DE--- 203
Query: 400 FSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+ ++L DFGL K+ I ++ + CG+ +Y++PE++ + + +D W+FGV+ +
Sbjct: 204 --EGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QSADWWSFGVLMFE 260
Query: 459 LLEDRLPF 466
+L LPF
Sbjct: 261 MLTGTLPF 268
Score = 58.5 bits (140), Expect = 2e-08
Identities = 58/248 (23%), Positives = 103/248 (41%), Gaps = 43/248 (17%)
Query: 271 ELLSRVVSSLKRELTTLISV-----HHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRC 325
E +++ KR+ T I + HP I+ L + D D +Y
Sbjct: 447 EFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYD-----DGKYVY----------- 490
Query: 326 DMIMSYCTGGDLFDLASKTKI-PNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKY 384
++ GG+L D + K + ++ ++ ++YLH ++HRD+K N+L
Sbjct: 491 -VVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY-- 547
Query: 385 TLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDE-MCTTRCGSEDYVSPEILLGLPYD 443
DES + + + DFG K++ + + T C + ++V+PE+L YD
Sbjct: 548 ---------VDESG--NPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYD 596
Query: 444 GRISDAWAFGVITYALLEDRLPFDPLPGQSSRR--TRSIAHRIARCDWKWLKNADTDHPA 501
D W+ GV+ Y +L PF P + R + + + W +DT A
Sbjct: 597 A-ACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDT---A 652
Query: 502 KEIVQNTL 509
K++V L
Sbjct: 653 KDLVSKML 660
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 77.8 bits (190), Expect = 4e-14
Identities = 78/265 (29%), Positives = 116/265 (43%), Gaps = 44/265 (16%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMI 328
K+L +R L+RE + HP IV+L +I + +F H L +
Sbjct: 46 KKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESF----HYL--------------V 87
Query: 329 MSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
TGG+LF D+ ++ + I ++ +I Y H N I+HRD+K EN+LL
Sbjct: 88 FDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAK 147
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ E G+ Y+SPE+L PY +
Sbjct: 148 GAA--------------VKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPV- 192
Query: 448 DAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP-AKEIV 505
D WA GVI Y LL PF D + + ++ A+ +W DT P AK ++
Sbjct: 193 DIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEW------DTVTPEAKSLI 246
Query: 506 QNTL-VRKSERWNMDQLCNTPYIRN 529
+ L V +R DQ P+I N
Sbjct: 247 DSMLTVNPKKRITADQALKVPWICN 271
>CE21086 [D] KOG0590 Checkpoint kinase and related serine/threonine protein
kinases
Length = 637
Score = 77.8 bits (190), Expect = 4e-14
Identities = 67/254 (26%), Positives = 112/254 (43%), Gaps = 52/254 (20%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
++ ++ + G+F V+L E + NP +K VAVK + + + + +YK
Sbjct: 342 EYKVVEHLCKGSFGQVHLCE-------LTRNPSVK-VAVKEVAVSGKSRKNLTAVQKEYK 393
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
+ R L+ + H ++++ + +T P + ++M
Sbjct: 394 ---------IHRRLS---KIGHENVIQMMKMIET-------PKF----------YSLVME 424
Query: 331 YCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
Y GGDLFD L + K +L +K++H+ I+HRDIKLEN+LL Y+
Sbjct: 425 YADGGDLFDELKEQEKFSRKDAHSYFKQLIKGLKFIHEQGIVHRDIKLENLLLVYS---- 480
Query: 390 MLLKEDESQFFSKNFVELADFGLCKKITPDE---MCTTRCGSEDYVSPEILLGLPYDGRI 446
E E +++ DFGL K D M + CGS+ Y +PE+ G Y G
Sbjct: 481 ----ESED---DPGTLKITDFGLATKYRKDGEEIMLSEDCGSKPYAAPEVCTGNDYRGPP 533
Query: 447 SDAWAFGVITYALL 460
D W+ GV+ +L
Sbjct: 534 VDIWSAGVVLMTML 547
Score = 70.9 bits (172), Expect = 5e-12
Identities = 41/145 (28%), Positives = 72/145 (49%), Gaps = 21/145 (14%)
Query: 327 MIMSYCTGGDLFDLASKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+I+SY GGDLF+ ++ + + R +L ++++H+ + HRDIK EN+LL
Sbjct: 96 LILSYADGGDLFEKINQHGGLGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLT-- 153
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKIT---PDEMCTTRCGSEDYVSPEILLGLPY 442
+++ADFG ++M CGS Y++PE+L G+ Y
Sbjct: 154 ---------------KSGILKIADFGFATMHRFNGAEQMLNAYCGSPPYIAPEVLTGIDY 198
Query: 443 DGRISDAWAFGVITYALLEDRLPFD 467
G D W+ GV+ A++ +P++
Sbjct: 199 RGPAVDIWSAGVVLIAMIAGAVPWE 223
>At5g08590 [T] KOG0583 Serine/threonine protein kinase
Length = 353
Score = 77.8 bits (190), Expect = 4e-14
Identities = 67/271 (24%), Positives = 115/271 (41%), Gaps = 39/271 (14%)
Query: 268 KYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDM 327
KY E ++ ++ RE+ S+ HP I++ + +T H +
Sbjct: 33 KYIERGRKIDENVAREIINHRSLKHPNIIRFKEV----ILTPTH-------------LAI 75
Query: 328 IMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
+M Y +GG+LFD + + + +L + Y H I HRD+KLEN LL +
Sbjct: 76 VMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSP 135
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRI 446
++ ++ DFG K + G+ Y++PE+L YDG+
Sbjct: 136 APLL---------------KICDFGYSKSSILHSRPKSTVGTPAYIAPEVLSRREYDGKH 180
Query: 447 SDAWAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIV 505
+D W+ GV Y +L PF DP ++ R+T RI +K K ++
Sbjct: 181 ADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKT---IQRIMAVQYKIPDYVHISQECKHLL 237
Query: 506 QNTLVRKS-ERWNMDQLCNTP-YIRNIIDKL 534
V S +R + ++ N P Y++N+ +L
Sbjct: 238 SRIFVTNSAKRITLKEIKNHPWYLKNLPKEL 268
>At1g54510 [R] KOG0589 Serine/threonine protein kinase
Length = 612
Score = 77.8 bits (190), Expect = 4e-14
Identities = 62/257 (24%), Positives = 104/257 (40%), Gaps = 71/257 (27%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
Q+ +++IG G+F + L + E K +K I+ R+
Sbjct: 3 QYEFLEQIGKGSFGSALL---------VRHKHEKKKYVLKKIRLARQT------------ 41
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
R S +E+ + + HP IV+ Y + +++
Sbjct: 42 ---QRTRRSAHQEMELISKMRHPFIVE----------------YKDSWVEKACYVCIVIG 82
Query: 331 YCTGGDLFDLASKT--------KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
YC GGD+ K+ K+ WL+ +L + ++YLH N I+HRD+K N+ L
Sbjct: 83 YCEGGDMAQAIKKSNGVHFQEEKLCKWLV-----QLLMGLEYLHSNHILHRDVKCSNIFL 137
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPY 442
D + L DFGL K +T D++ ++ G+ Y+ PE+L +PY
Sbjct: 138 TKEQD-----------------IRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLADIPY 180
Query: 443 DGRISDAWAFGVITYAL 459
G SD W+ G Y +
Sbjct: 181 -GSKSDIWSLGCCIYEM 196
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 77.4 bits (189), Expect = 5e-14
Identities = 73/263 (27%), Positives = 112/263 (41%), Gaps = 68/263 (25%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
I+ +GSG F+ V L ++ K+ A+K I + LL SS
Sbjct: 170 IRTLGSGTFAVVKLAVEVNSG---------KWYAIKIINKRKILLTSSE----------K 210
Query: 275 RVVSSLKRELTTLISVHHPCIVK---LFAINDTTFITDEHPLYGRRKLSALPRCDMIMSY 331
R +RE+ L S+HHP +V+ +F +D FI +M Y
Sbjct: 211 RATEMFQREIDILKSLHHPGVVQCHEIFENDDELFI--------------------VMEY 250
Query: 332 CTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMM 390
GGDL D L + I ++ +L + +LH + HRDIK EN+L+ +D
Sbjct: 251 VEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILI---TNDFH 307
Query: 391 LLKEDESQFFSKNFVELADFGLCKKI-TPDEMCTTRCGSEDYVSPEIL------LGLPYD 443
L +++DFGL K I T CG+ Y++PE+L L YD
Sbjct: 308 L--------------KISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYD 353
Query: 444 GRISDAWAFGVITYALLEDRLPF 466
++ D W+ G + Y +L +PF
Sbjct: 354 DKV-DIWSLGCVLYVMLTASIPF 375
>CE03492 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 379
Score = 77.4 bits (189), Expect = 5e-14
Identities = 75/262 (28%), Positives = 115/262 (43%), Gaps = 64/262 (24%)
Query: 212 WSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKE 271
+S I+ IG G F V CI + KY A+K + K +
Sbjct: 28 FSVIRSIGRGAFGKV----CI-----VQERKTKKYFALKYMN--------------KRRC 64
Query: 272 LLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSY 331
+ V +++ RELT L + HP IV L+ TF ++ +Y M+
Sbjct: 65 IEKGVAANVIRELTLLSKMSHPFIVNLWY----TFQDGDY-MY------------MVSDL 107
Query: 332 CTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMM 390
GGDL + L+ + K + E+ +A++YLH+ I+HRDIK EN+LL
Sbjct: 108 LLGGDLRYHLSQQGKFAEDRAKLYLCEICLAVEYLHEMKIVHRDIKPENILL-------- 159
Query: 391 LLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEIL-----LGLPYDGR 445
DE + L D L ++ D++ T+ G+ Y++PEI + YD R
Sbjct: 160 ----DE-----QGHAHLTDLNLATQLEDDQLATSYSGTRPYMAPEIYATYLEIEDGYDSR 210
Query: 446 ISDAWAFGVITYALLEDRLPFD 467
+ D WA GV Y +L R PF+
Sbjct: 211 V-DWWALGVCFYEMLRGRTPFE 231
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 77.4 bits (189), Expect = 5e-14
Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 17/141 (12%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWLLTRIITE-LSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M C GG+LF K + + R++ + L +K+ HD+ I+HRD+K EN+L+
Sbjct: 120 LVMELCAGGELFHKLEKYGRYSEVRARVLFKHLMQVVKFCHDSGIVHRDLKPENILM--- 176
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+ S + ++LADFGL I P E + GS Y++PE+L G Y+ +
Sbjct: 177 -----------ATMSSSSPIKLADFGLATYIKPGEKLSGTVGSPFYIAPEVLAG-GYN-Q 223
Query: 446 ISDAWAFGVITYALLEDRLPF 466
+D W+ GVI Y LL PF
Sbjct: 224 AADVWSAGVILYILLSGAPPF 244
>7298926 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 704
Score = 77.4 bits (189), Expect = 5e-14
Identities = 88/422 (20%), Positives = 167/422 (38%), Gaps = 103/422 (24%)
Query: 48 EAIDVGMLPTPTANVFT--SPVRVNKSPGGFDAGLQVEKRRNKDSASNSGVPSPTISSVD 105
E + ++P P A T +P++ +++PGG A N + +
Sbjct: 303 EDLQPAIIPMPVAPATTPATPLQNHRTPGGISAPAASPMMHNNATTT------------- 349
Query: 106 THEEVLDEELSKLGTYMNRDVTHKIKGRMLSEYIPNNSMGDGSGGVAVQRSISLNNRVVE 165
LD+ + Y ++ S + N + VA + + +
Sbjct: 350 -----LDKNKNNANLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAK 404
Query: 166 KPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMANTPNHISFQWSKIKEIGSGNFST 225
K + E I+ ++ T V N + ++K+++IG G T
Sbjct: 405 KKKMSDEEILEKLRTIVSVGDPNRK---------------------YTKMEKIGQGASGT 443
Query: 226 VYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVSSLKRELT 285
VY I+ + + VA+K + ++ PK KEL+ E+
Sbjct: 444 VYT--AIESSTGME-------VAIKQMNLSQQ---------PK-KELIIN-------EIL 477
Query: 286 TLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLASKTK 345
+ HP +V D+ +++E ++M Y GG L D+ ++T
Sbjct: 478 VMRENKHPNVVNYL---DSYLVSEE--------------LWVVMEYLPGGSLTDVVTETC 520
Query: 346 IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFV 405
+ + + E+ A+++LH N +IHRDIK +N+LL LD V
Sbjct: 521 MDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILL--GLD---------------GSV 563
Query: 406 ELADFGLCKKITPDE-MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRL 464
+L DFG C +I+P++ TT G+ +++PE++ Y ++ D W+ G++ ++E
Sbjct: 564 KLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKV-DLWSLGIMAIEMVEGEP 622
Query: 465 PF 466
P+
Sbjct: 623 PY 624
>YAL017w [T] KOG1152 Signal transduction serine/threonine kinase with PAS/PAC
sensor domain
Length = 1356
Score = 77.0 bits (188), Expect = 7e-14
Identities = 83/335 (24%), Positives = 136/335 (39%), Gaps = 57/335 (17%)
Query: 143 SMGDGSGGVAVQRSISLNNRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMA 202
S+ + +A +S +E+ L E + P D+ DG I+
Sbjct: 1016 SLSPSTESLADSKSSGKGLSPLEEEKLIDENATENGLAGSPKDE------DGIIMTNKRG 1069
Query: 203 NTPNHISFQWSKIKEIG--------SGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKY 254
N P +F + K IG S S + E +N+ ++ + +Y+ V + +
Sbjct: 1070 NQPVS-TFLRTPEKNIGAQKHVKKFSDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIF 1128
Query: 255 PRELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAI-NDTTFITDEHPL 313
+L+ + K + S + + + TL H I++L D + E P+
Sbjct: 1129 KERILVDTWVRDRKLGTIPSEI-----QIMATLNKKPHENILRLLDFFEDDDYYYIETPV 1183
Query: 314 YGRRKLSALPRCDMIMSYCTGG-DLFDLAS-KTKIPNWLLTRIITELSVAIKYLHDNFII 371
+G TG DLFDL KT + + I ++ IK+LHD I+
Sbjct: 1184 HGE----------------TGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIV 1227
Query: 372 HRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDY 431
HRDIK ENV++ SK FV++ DFG + G+ DY
Sbjct: 1228 HRDIKDENVIVD-----------------SKGFVKIIDFGSAAYVKSGPF-DVFVGTIDY 1269
Query: 432 VSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
+PE+L G PY+G+ D WA G++ Y ++ PF
Sbjct: 1270 AAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPF 1304
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 77.0 bits (188), Expect = 7e-14
Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 28/191 (14%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+++++ GG+LF L + + I EL VA++ LH+ +I+RD+K EN+LL YT
Sbjct: 305 LVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIYRDLKPENILLDYT 364
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCK-KITPDEMCTTRCGSEDYVSPEILLGLPYDG 444
+ L DFGLCK + + T CG+ +Y++PE+LLG Y
Sbjct: 365 -----------------GHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYT- 406
Query: 445 RISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEI 504
++ D W GV+ Y ++ PF + +I + ++ N D AK++
Sbjct: 407 KVVDWWTLGVLLYEMITGLPPF------YDENINEMYRKILQDPLRFPDN--IDEKAKDL 458
Query: 505 VQNTLVRKSER 515
+ L R E+
Sbjct: 459 LSGLLTRAPEK 469
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 77.0 bits (188), Expect = 7e-14
Identities = 78/314 (24%), Positives = 129/314 (40%), Gaps = 71/314 (22%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G G F VYL E ++V + + R++ S+ V
Sbjct: 160 LGRGKFGNVYLAR----------EKESQFVVALKVLFKRQIGESN-------------VE 196
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
++RE+ + HP I++L+A + D+ +Y +I+ Y G L
Sbjct: 197 HQVRREIEIQSHLRHPHILRLYA-----YFHDDVRIY------------LILEYAPQGTL 239
Query: 338 FDLASKTKIPNW---LLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
F+ + + I L A+ YLH+ IIHRDIK EN+LL +
Sbjct: 240 FNALQAQPMKRFDERQSATYIQALCSALLYLHERDIIHRDIKPENLLLGH---------- 289
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
K +++ADFG P+ M T CG+ DY+ PE++ G P+ + D W+ GV
Sbjct: 290 -------KGVLKIADFGWSVH-EPNSMRMTLCGTVDYLPPEMVQGKPHTKNV-DLWSLGV 340
Query: 455 ITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLV-RKS 513
+ + LL PF S+ +I + D+K ++ A ++ LV
Sbjct: 341 LCFELLVGHAPF------YSKNYDETYKKILKVDYKLPEH--ISKAASHLISKLLVLNPQ 392
Query: 514 ERWNMDQLCNTPYI 527
R +DQ+ P+I
Sbjct: 393 HRLPLDQVMVHPWI 406
>7298698 [T] KOG4250 TANK binding protein kinase TBK1
Length = 711
Score = 77.0 bits (188), Expect = 7e-14
Identities = 57/207 (27%), Positives = 91/207 (43%), Gaps = 39/207 (18%)
Query: 282 RELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLA 341
RE L V+H IVKL AI E GR K+ ++M CTGG LF++
Sbjct: 57 REFEALKKVNHENIVKLLAI--------EEDQEGRGKV-------IVMELCTGGSLFNIL 101
Query: 342 SKTK----IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ +P ++ L +K+L DN ++HRD+K N+ M + ED
Sbjct: 102 DDPENSYGLPEHEFLLVLEHLCAGMKHLRDNKLVHRDLKPGNI--------MKFISED-- 151
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS-------DAW 450
+ +L DFG +++ ++ + G+E+Y+ P++ I D W
Sbjct: 152 ---GQTIYKLTDFGAARELEDNQPFASLYGTEEYLHPDLYERAVLRKSIQRSFTANVDLW 208
Query: 451 AFGVITYALLEDRLPFDPLPGQSSRRT 477
+ GV Y + LPF P G+ +R T
Sbjct: 209 SIGVTLYHVATGNLPFRPFGGRKNRET 235
>YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 898
Score = 76.6 bits (187), Expect = 9e-14
Identities = 87/331 (26%), Positives = 145/331 (43%), Gaps = 65/331 (19%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
+E+G G++STV+ D + N +K + K I KE +
Sbjct: 15 EELGHGSYSTVFKAL---DKKSPNKIYAIKVCSKKHI----------------IKEAKVK 55
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
V+ K + L HH I+KL+ TF DE LY ++ + GG
Sbjct: 56 YVTIEKNTMNLLAQKHHAGIIKLYY----TF-HDEENLY------------FVLDFAPGG 98
Query: 336 DLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+L L K N + TR T +L A++++H + IIHRD+K ENVLL D +++
Sbjct: 99 ELLSLLHKMGTFNDIWTRHFTAQLIDALEFIHSHGIIHRDLKPENVLL--DRDGRLMI-- 154
Query: 395 DESQFFSKNFVELADFGLCKKITPD-------EMCTTRCGSEDYVSPEILLGLPYDGRIS 447
+ F + ++ + G K D + C + G+ +YVSPE+LL G S
Sbjct: 155 --TDFGAAATIDPSLSGDSAKFNSDSNGSKDNQNCASFVGTAEYVSPELLL-YNQCGYGS 211
Query: 448 DAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKN---ADTDHPAKEI 504
D WA G + Y ++ + PF G++ +T +I D+ W N ++ P +
Sbjct: 212 DIWALGCMIYQFVQGQPPF---RGENELKT---FEKIVALDYPWGPNNRINNSTSPINPL 265
Query: 505 VQN-----TLVRKSERWNMDQLCNTPYIRNI 530
V N ++ +ER +++Q+ PY +
Sbjct: 266 VINLVQKILVIEVNERISLEQIKRHPYFSKV 296
>YDR122w [T] KOG0583 Serine/threonine protein kinase
Length = 1064
Score = 76.6 bits (187), Expect = 9e-14
Identities = 44/142 (30%), Positives = 71/142 (49%), Gaps = 18/142 (12%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
M+ Y +GG L D + I + ++ A+ YLH N I+HRD+K+EN+++
Sbjct: 221 MLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMIS-- 278
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
D S+ +++ DFGL + T CGS + +PE+L PY G
Sbjct: 279 ---------DSSE------IKIIDFGLSNIYDSRKQLHTFCGSLYFAAPELLKANPYTGP 323
Query: 446 ISDAWAFGVITYALLEDRLPFD 467
D W+FGV+ + L+ ++PFD
Sbjct: 324 EVDVWSFGVVLFVLVCGKVPFD 345
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 504
Score = 76.6 bits (187), Expect = 9e-14
Identities = 90/348 (25%), Positives = 147/348 (41%), Gaps = 71/348 (20%)
Query: 201 MANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLM 260
+AN P +Q I+ +G G FS VY ID ++VAVK I+
Sbjct: 56 VANYPGLEKYQL--IENLGDGAFSQVYKAYSIDRK---------EHVAVKVIR------- 97
Query: 261 SSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLS 320
KY E+ + + +E+ + V H +V LF +T Y
Sbjct: 98 -------KY-EMNKKQRQGVFKEVNIMRRVKHKNVVNLFDFVET------EDFY------ 137
Query: 321 ALPRCDMIMSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNF-IIHRDIKLE 378
++M GG+LF + + T L II +++ A+K+LHD I+HRDIK E
Sbjct: 138 -----HLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHLHDVCGIVHRDIKPE 192
Query: 379 NVLLK---------YTLDDMMLLKEDESQFFSK------NFVELADFGLCKKITPDEMCT 423
N+L + YT + K DE F + +ADFG K+ +
Sbjct: 193 NLLFQPIEYLPSQNYTPPSLEPNKLDEGMFLEGIGAGGIGRILIADFGF-SKVVWNSKTA 251
Query: 424 TRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHR 483
T CG+ Y +PEI+ Y + D WA G + + +L PF + +A +
Sbjct: 252 TPCGTVGYAAPEIVNDELYSKNV-DMWAMGCVLHTMLCGFPPF------FDENIKDLASK 304
Query: 484 IARCDWKWLKN--ADTDHPAKEIVQNTL-VRKSERWNMDQLCNTPYIR 528
+ ++++L D AK+++ + L V ER+++ Q P+I+
Sbjct: 305 VVNGEFEFLSPWWDDISDSAKDLITHLLTVDPRERYDIHQFFQHPWIK 352
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 76.6 bits (187), Expect = 9e-14
Identities = 55/194 (28%), Positives = 90/194 (46%), Gaps = 37/194 (19%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ +KRE++ + + HP IV+L + T + +Y +M + GG
Sbjct: 53 MTEQIKREISAMRLLRHPNIVELHEVMAT-----KSKIY------------FVMEHVKGG 95
Query: 336 DLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+LF+ S K+ + + +L A+ + H + HRD+K EN+LL D
Sbjct: 96 ELFNKVSTGKLREDVARKYFQQLVRAVDFCHSRGVCHRDLKPENLLL------------D 143
Query: 396 ESQFFSKNFVELADFGLCK---KITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
E ++++DFGL D + T CG+ YV+PE++ YDG +D W+
Sbjct: 144 EH-----GNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSC 198
Query: 453 GVITYALLEDRLPF 466
GVI + LL LPF
Sbjct: 199 GVILFVLLAGYLPF 212
>At1g78290 [T] KOG0583 Serine/threonine protein kinase
Length = 343
Score = 76.6 bits (187), Expect = 9e-14
Identities = 70/265 (26%), Positives = 107/265 (39%), Gaps = 61/265 (23%)
Query: 215 IKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLS 274
+K+IGSGNF L K+ +EL + K+ E
Sbjct: 7 VKDIGSGNFGVAKLVRD---------------------KFSKELF------AVKFIERGQ 39
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
++ ++RE+ S+ HP I++ + +T H ++M Y G
Sbjct: 40 KIDEHVQREIMNHRSLIHPNIIRFKEV----LLTATH-------------LALVMEYAAG 82
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G+LF + S + +L + Y H I HRD+KLEN LL
Sbjct: 83 GELFGRICSAGRFSEDEARFFFQQLISGVNYCHSLQICHRDLKLENTLL----------- 131
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
D S+ V++ DFG K T G+ Y++PE+L YDG+I+D W+ G
Sbjct: 132 -DGSE---APRVKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYDGKIADVWSCG 187
Query: 454 VITYALLEDRLPF-DPLPGQSSRRT 477
V Y +L PF DP + R+T
Sbjct: 188 VTLYVMLVGAYPFEDPSDPKDFRKT 212
>YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 897
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/284 (27%), Positives = 119/284 (41%), Gaps = 77/284 (27%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
KEIG G+F+TVY D + ++VA+K + S + K K+LL
Sbjct: 28 KEIGKGSFATVYRGHLTSD--------KSQHVAIKEV----------SRAKLKNKKLLE- 68
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+L+ E+ L + HP IV L T+ TD + +IM YC G
Sbjct: 69 ---NLEIEIAILKKIKHPHIVGLIDCERTS--TDFY---------------LIMEYCALG 108
Query: 336 DLFDLASKTK--IPNWLLTRIITE-----------------------LSVAIKYLHDNFI 370
DL L + K + N L R + E L+ A+K+L +
Sbjct: 109 DLTFLLKRRKELMENHPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNL 168
Query: 371 IHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFV--------ELADFGLCKKITPDEMC 422
+HRDIK +N+LL L + D F FV ++ADFG + + +
Sbjct: 169 VHRDIKPQNLLLSTPL----IGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLA 224
Query: 423 TTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
T CGS Y++PEIL Y+ + +D W+ G + + + PF
Sbjct: 225 ETLCGSPLYMAPEILNYQKYNAK-ADLWSVGTVVFEMCCGTPPF 267
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 76.3 bits (186), Expect = 1e-13
Identities = 68/260 (26%), Positives = 116/260 (44%), Gaps = 50/260 (19%)
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
V LKRE+ + HP I+ L+ + D+ ++ +I+ Y + G
Sbjct: 85 VSHQLKREIEIQYHLRHPNILTLYG-----YFHDDKRVF------------VILDYASRG 127
Query: 336 DLFDLASKT---KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
+LF++ K+ + R + +L+ A+ Y H +IHRDIK EN+LL
Sbjct: 128 ELFNVLQSQPGHKVNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLD--------- 178
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
SK ++LADFG + T CG+ DY++PE++ P+D + D WA
Sbjct: 179 --------SKLNLKLADFG-WSVVADHSKRHTLCGTMDYLAPEMVSNQPHDFNV-DIWAI 228
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK 512
G++ + +L PF G + RI C ++ + TD A I N +++K
Sbjct: 229 GILLFEMLVGYAPFANQTGD------KLIARIKECK-IYIPSVVTDGAASLI--NAIIKK 279
Query: 513 --SERWNMDQLCNTPYIRNI 530
ER + + P+I+ +
Sbjct: 280 EPQERLPLVDIMAHPWIKEM 299
>At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 470
Score = 76.3 bits (186), Expect = 1e-13
Identities = 60/209 (28%), Positives = 94/209 (44%), Gaps = 25/209 (11%)
Query: 327 MIMSYCTGGDLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M C+GG L D K + I +L + I Y H+ ++HRDIK EN+LL
Sbjct: 176 LVMELCSGGRLIDQMVKVGRYSEQRAANIFKDLMLVINYCHEMGVVHRDIKPENILLT-- 233
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+ ++LADFGL +I + + GS YV+PE+ L Y +
Sbjct: 234 ---------------AAGKIQLADFGLAMRIAKGQTLSGLAGSPAYVAPEV-LSENYSEK 277
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIV 505
+ D W+ GV+ YALL LPF S A + + D+ PA++++
Sbjct: 278 V-DVWSAGVLLYALLSGVLPFK----GDSLDAIFEAIKNVKLDFNTGVWESVSKPARDLL 332
Query: 506 QNTLVR-KSERWNMDQLCNTPYIRNIIDK 533
L R +S R D++ P+I D+
Sbjct: 333 ARMLTREESARITADEVLRHPWILFYTDR 361
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 76.3 bits (186), Expect = 1e-13
Identities = 45/148 (30%), Positives = 78/148 (52%), Gaps = 20/148 (13%)
Query: 322 LPRCDMIMSYCTGGDL-FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENV 380
+ R +M YC GGDL + + + + E+++A+ +LH+ II+RD+KL+N+
Sbjct: 442 MDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNI 501
Query: 381 LLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLG 439
LL + V+L DFGL K+ +T + T CG+ +Y++PEI+
Sbjct: 502 LLD-----------------GEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSY 544
Query: 440 LPYDGRISDAWAFGVITYALLEDRLPFD 467
PY +D W+FGV+ + + + PF+
Sbjct: 545 DPY-SIAADWWSFGVLLFEFMAGQAPFE 571
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 75.9 bits (185), Expect = 1e-13
Identities = 54/191 (28%), Positives = 93/191 (48%), Gaps = 36/191 (18%)
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
+S+ E+ + + HP I++L+ + TD +Y + + Y G+L
Sbjct: 48 ASIGMEILMMRLLRHPNILRLYDV-----WTDHQHMY------------LALEYVPDGEL 90
Query: 338 FDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDE 396
F K + ++++ A+ + H HRD+KLEN+L+K +E
Sbjct: 91 FHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRFRHRDLKLENILIKV----------NE 140
Query: 397 SQFFSKNFVELADFGLCKKITPDEMCTTR-CGSEDYVSPEILLGLPYDGRISDAWAFGVI 455
Q +++ADFG+ + P++ C CGS Y++PEI+ PY G +D W+ GVI
Sbjct: 141 QQ------IKIADFGMAT-VEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWSCGVI 193
Query: 456 TYALLEDRLPF 466
Y+LL ++LPF
Sbjct: 194 LYSLLSNKLPF 204
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 75.9 bits (185), Expect = 1e-13
Identities = 61/217 (28%), Positives = 100/217 (45%), Gaps = 40/217 (18%)
Query: 327 MIMSYCTGGDLFDLASKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+I+ C L +L K K + + ++ ++ A+KY+H +IHRD+KL N++L
Sbjct: 115 LILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIML--- 171
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPD-EMCTTRCGSEDYVSPEILLGLPYDG 444
DES N V++ DFGL + D E T CG+ +Y++PEIL
Sbjct: 172 ---------DES-----NNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGH 217
Query: 445 RIS-DAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKE 503
D W+ GV+ YALL + PF + ++I +I + + N D AK+
Sbjct: 218 SFEVDLWSAGVVMYALLIGKPPF------QDKEVKTIYRKIKANSYSFPSNVDISAEAKD 271
Query: 504 IVQNTLVRKSERWNMDQLCNTPYIRNIIDKLQFLDHQ 540
++ + L + P IR ID + +DH+
Sbjct: 272 LISSLLT------------HDPSIRPSIDDI--VDHE 294
>SPAC1805.01c [T] KOG1152 Signal transduction serine/threonine kinase with
PAS/PAC sensor domain
Length = 713
Score = 75.9 bits (185), Expect = 1e-13
Identities = 84/314 (26%), Positives = 137/314 (42%), Gaps = 57/314 (18%)
Query: 158 SLNNRVVE-KPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMANTPNHISFQWSKIK 216
S++NR + S++ I+ EV+ S S++E + AD + P++I+ ++ IK
Sbjct: 449 SVDNRASDFVRSMRSSVILEEVVISDESEEEEDLSADEDYVDSEWEVVPHNIA-SYTTIK 507
Query: 217 EIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRV 276
E+G G + V L + ++ V +KSI R LL S + +
Sbjct: 508 ELGIGAYGQVKLATYKSNKVH--------EVILKSISKSRILLDSW---------MRDKD 550
Query: 277 VSSLKRELTTL--ISVH-HPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
+ ++ E++ L + H HP IVK+ TF D Y L P+
Sbjct: 551 LGTVPMEISILHFLKAHSHPNIVKMI-----TFFEDNENYY----LLTEPQKP------- 594
Query: 334 GGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
G DLFD + K I I ++++A+ +LH IIHRDIK ENV+L+
Sbjct: 595 GIDLFDYIELKPSISEKESKAIFFQIALAVAHLHSFDIIHRDIKDENVILE--------- 645
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
L DFG +T + T G+ + +PE+L G Y G+ D WA
Sbjct: 646 --------GNGCARLIDFG-SSSLTKNGPFDTFRGTVGFAAPELLRGEKYLGKEQDIWAL 696
Query: 453 GVITYALLEDRLPF 466
G++ Y ++ P+
Sbjct: 697 GILLYTIVYRENPY 710
>Hs20547878 [R] KOG0589 Serine/threonine protein kinase
Length = 758
Score = 75.9 bits (185), Expect = 1e-13
Identities = 57/221 (25%), Positives = 100/221 (44%), Gaps = 41/221 (18%)
Query: 324 RCDMIMSYCTGGDLFD--------LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDI 375
R ++M YC GGDL L S+ +I W + ++S+ +K++HD I+HRDI
Sbjct: 51 RLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFV-----QISLGLKHIHDRKILHRDI 105
Query: 376 KLENVLLKYTLDDMMLLKEDESQFFSKN--FVELADFGLCKKITPD-EMCTTRCGSEDYV 432
K +N+ F SKN +L DFG+ + + E+ T G+ Y+
Sbjct: 106 KAQNI------------------FLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYL 147
Query: 433 SPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWL 492
SPEI PY+ + +D W+ G + Y L + PF+ + + +I + + +
Sbjct: 148 SPEICQNKPYNNK-TDIWSLGCVLYELCTLKHPFE------GNNLQQLVLKICQAHFAPI 200
Query: 493 KNADTDHPAKEIVQNTLVRKSERWNMDQLCNTPYIRNIIDK 533
+ I Q V +R +++ + P++ N+I K
Sbjct: 201 SPGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPK 241
>ECU08g1480 [R] KOG0586 Serine/threonine protein kinase
Length = 467
Score = 75.9 bits (185), Expect = 1e-13
Identities = 49/170 (28%), Positives = 79/170 (45%), Gaps = 27/170 (15%)
Query: 361 AIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDE 420
A+ YLH + I+HRD+KLENV++ S V++ DFGL
Sbjct: 115 AVDYLHTHSIVHRDLKLENVMI------------------SGETVKICDFGLSTFYDSSS 156
Query: 421 MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSI 480
+ CG+ PEI+ G+PY G D W GVI YA++ +LPF+ + S R +
Sbjct: 157 VLRDYCGTPQCAPPEIMNGIPYIGPEVDIWCLGVILYAMVHGKLPFEDGDTKLSSRHAIV 216
Query: 481 AHRIARCDWKWLKNADTDHPAKEIVQNTL-VRKSERWNMDQLCNTPYIRN 529
+ K + +++++ T+ +S R MDQ+ P+I +
Sbjct: 217 S--------KMRIDESLSSELRDLIRKTIEPDRSMRIKMDQMMEHPWINS 258
>YPL153c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 821
Score = 75.5 bits (184), Expect = 2e-13
Identities = 60/203 (29%), Positives = 91/203 (44%), Gaps = 45/203 (22%)
Query: 277 VSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGD 336
+ + REL L ++HP IV+L F D Y M+M + +GGD
Sbjct: 238 MDGVTRELEVLQKLNHPRIVRLKG-----FYEDTESYY------------MVMEFVSGGD 280
Query: 337 LFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
L D +A+ + I ++ AIKY+H I HRD+K +N+L++ DD +L+K
Sbjct: 281 LMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLKPDNILIEQ--DDPVLVK-- 336
Query: 396 ESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGL-------PYDGR--- 445
+ DFGL K T CG+ YV+PE++ G Y+ R
Sbjct: 337 -----------ITDFGLAKVQGNGSFMKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEY 385
Query: 446 --ISDAWAFGVITYALLEDRLPF 466
+ D W+ G + Y +L LPF
Sbjct: 386 SSLVDMWSMGCLVYVILTGHLPF 408
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/192 (28%), Positives = 92/192 (47%), Gaps = 46/192 (23%)
Query: 281 KRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF-- 338
KR L + S HP +V LF F T EH + +M Y GGDL
Sbjct: 664 KRILAAVTSAGHPFLVNLFGC----FQTPEHVCF-------------VMEYSAGGDLMLH 706
Query: 339 ---DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
D+ S+ + + ++ +++LH++ I++RD+KL+N+LL
Sbjct: 707 IHSDVFSEPRAIFYSACVVL-----GLQFLHEHKIVYRDLKLDNLLLD------------ 749
Query: 396 ESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++ +V++ADFGLCK+ + + +T CG+ ++++PE+L Y R D W GV
Sbjct: 750 -----TEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYT-RAVDWWGLGV 803
Query: 455 ITYALLEDRLPF 466
+ Y +L PF
Sbjct: 804 LLYEMLVGESPF 815
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/192 (28%), Positives = 92/192 (47%), Gaps = 46/192 (23%)
Query: 281 KRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF-- 338
KR L + S HP +V LF F T EH + +M Y GGDL
Sbjct: 664 KRILAAVTSAGHPFLVNLFGC----FQTPEHVCF-------------VMEYSAGGDLMLH 706
Query: 339 ---DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
D+ S+ + + ++ +++LH++ I++RD+KL+N+LL
Sbjct: 707 IHSDVFSEPRAIFYSACVVL-----GLQFLHEHKIVYRDLKLDNLLLD------------ 749
Query: 396 ESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
++ +V++ADFGLCK+ + + +T CG+ ++++PE+L Y R D W GV
Sbjct: 750 -----TEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYT-RAVDWWGLGV 803
Query: 455 ITYALLEDRLPF 466
+ Y +L PF
Sbjct: 804 LLYEMLVGESPF 815
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 75.5 bits (184), Expect = 2e-13
Identities = 74/309 (23%), Positives = 129/309 (40%), Gaps = 70/309 (22%)
Query: 168 SLKKETIINEVITSVPSDKENEQKADGTI------IRGYMANTPNHISFQWSKIKEI--- 218
S++ E+ NE S D N + + + ++ TP SF S+++ I
Sbjct: 10 SVEDESCSNECSASFTFDTNNNSRGNNQVNELAEETHMKLSITPTRESFSLSQLERIITI 69
Query: 219 GSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVVS 278
G G F V E D + + A+K + R + M R
Sbjct: 70 GKGTFGRV---ELARDKITG------AHYALKVLNIRRVVDM--------------RQTQ 106
Query: 279 SLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLF 338
+ E L+ + HP IVK++A D + LY MIM + GG++F
Sbjct: 107 HVHNEKRVLLQLKHPFIVKMYASEK-----DSNHLY------------MIMEFVPGGEMF 149
Query: 339 D-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
L + N + +E+ A++Y+H I++RD+K EN++L
Sbjct: 150 SYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLS-------------- 195
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
+ +++ADFG K++ + T CG+ DY++PE L ++ + D WA G++ Y
Sbjct: 196 ---KEGHIKMADFGFAKELR--DRTYTICGTPDYLAPESLARTGHNKGV-DWWALGILIY 249
Query: 458 ALLEDRLPF 466
++ + PF
Sbjct: 250 EMMVGKPPF 258
>7304283 [Z] KOG0613 Projectin/twitchin and related proteins
Length = 7175
Score = 75.5 bits (184), Expect = 2e-13
Identities = 63/245 (25%), Positives = 112/245 (45%), Gaps = 53/245 (21%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
++RE+ + +HH KL ++D DE L I+ + +GG+LF+
Sbjct: 6180 IRREIDIMNQLHHQ---KLINLHDAFEDDDEMIL--------------ILEFLSGGELFE 6222
Query: 340 -------LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
+ ++ ++ N++ ++ I+++H+ IIH DIK EN++
Sbjct: 6223 RITAEGYVMTEAEVINYM-----RQICEGIRHMHEQNIIHLDIKPENIMC---------- 6267
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
Q S V+L DFGL ++ P+E+ G+ ++ +PEI+ P G +D WA
Sbjct: 6268 -----QTRSSTNVKLIDFGLATRLDPNEVVKITTGTAEFAAPEIVNREPV-GFYTDMWAT 6321
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNA--DTDHPAKEIVQNTLV 510
GV++Y LL PF G + +T + CDW + + AK+ ++ LV
Sbjct: 6322 GVLSYVLLSGLSPF---AGDNDVQT---LKNVKACDWDFDVESFKYISEEAKDFIRKLLV 6375
Query: 511 RKSER 515
R E+
Sbjct: 6376 RNKEK 6380
>YOR233w [T] KOG0583 Serine/threonine protein kinase
Length = 800
Score = 75.1 bits (183), Expect = 3e-13
Identities = 55/210 (26%), Positives = 96/210 (45%), Gaps = 27/210 (12%)
Query: 261 SSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLS 320
SSS PK + ++K++ I ++ IN +T + +Y L
Sbjct: 68 SSSNEVPKQVAIKLIRRDTIKKDADKEIKIYRE-------INALKHLTHPNIIYLEEVLQ 120
Query: 321 ALPRCDMIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLEN 379
+++ + +GG+ + + K ++ R+ +L + Y+H ++HRD+KLEN
Sbjct: 121 NSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLEN 180
Query: 380 VLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPD-EMCTTRCGSEDYVSPEILL 438
+LL +N V + DFG + D E+ T CGS Y +PE+++
Sbjct: 181 LLLDK----------------HENLV-ITDFGFVNEFFEDNELMKTSCGSPCYAAPELVV 223
Query: 439 GL-PYDGRISDAWAFGVITYALLEDRLPFD 467
Y+ R +D W+ GVI YA+L LP+D
Sbjct: 224 STKAYEARKADVWSCGVILYAMLAGYLPWD 253
>Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1
Length = 756
Score = 75.1 bits (183), Expect = 3e-13
Identities = 49/198 (24%), Positives = 92/198 (45%), Gaps = 23/198 (11%)
Query: 327 MIMSYCTGGDLFDLASKTK----IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLL 382
+ M YC GGDL ++ + + + ++++++ A++YLH+N IIHRD+K EN+
Sbjct: 94 LAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENI-- 151
Query: 383 KYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPY 442
+L++ E + K + D G K++ +CT+ G+ Y++PE+L Y
Sbjct: 152 --------VLQQGEQRLIHK----IIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKY 199
Query: 443 DGRISDAWAFGVITYALLEDRLPF----DPLPGQSSRRTRSIAHRIARCDWKWLKNADTD 498
+ D W+FG + + + PF P+ S R +S + D +
Sbjct: 200 TVTV-DYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSS 258
Query: 499 HPAKEIVQNTLVRKSERW 516
P + + L + E+W
Sbjct: 259 LPYPNNLNSVLAERLEKW 276
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 75.1 bits (183), Expect = 3e-13
Identities = 71/265 (26%), Positives = 120/265 (44%), Gaps = 37/265 (13%)
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
S L+ E+ L S+ HP IV L + F T E KL +MI+S
Sbjct: 593 SQLRNEVAILQSLRHPGIVNL----ECMFETPEKVFVVMEKLHG-DMLEMILS------- 640
Query: 338 FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ K ++P L +IT++ VA+++LH I+H D+K ENVLL +
Sbjct: 641 ---SEKGRLPERLTKFLITQILVALRHLHFKNIVHCDLKPENVLLA------------SA 685
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
F + V+L DFG + I + G+ Y++PE+LL Y+ R D W+ GVI Y
Sbjct: 686 DPFPQ--VKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYN-RSLDMWSVGVIMY 742
Query: 458 ALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTL-VRKSERW 516
L PF+ + + ++ A W + A +++ N L V+ +R+
Sbjct: 743 VSLSGTFPFNE-DEDINDQIQNAAFMYPASPWSHISAG-----AIDLINNLLQVKMRKRY 796
Query: 517 NMDQLCNTPYIRNIIDKLQFLDHQG 541
++D+ + P+++ L + +G
Sbjct: 797 SVDKSLSHPWLQEYQTWLDLRELEG 821
>YNR031c [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 and related
serine/threonine protein kinases
Length = 1579
Score = 74.7 bits (182), Expect = 3e-13
Identities = 78/340 (22%), Positives = 142/340 (40%), Gaps = 74/340 (21%)
Query: 153 VQRSISLNNRVVEKPSLKKETIINEVITSVPSDKENEQKADGTIIRGYMANTPNHISFQW 212
VQ + L R+ P + I + SDK N+ +A++ +++S +W
Sbjct: 1221 VQSIMELEERIKRNPHQTGKVIDD-------SDKGNKYLVS-------LASSISNVSMRW 1266
Query: 213 SKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKEL 272
K IG G F VY +D+ + +AVK I + S S
Sbjct: 1267 QKRNFIGGGTFGRVYSAVDLDNG---------EILAVKEIN------IQDSKS------- 1304
Query: 273 LSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYC 332
+ ++ +K E++ L ++HP IV + + R K++ + M YC
Sbjct: 1305 MQKIFPLIKEEMSVLEILNHPNIVSYYGVE-----------VHRDKVN------IFMEYC 1347
Query: 333 TGGDLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYT------ 385
GG L L +I + ++T++ T +L + YLH++ I+HRD+K EN+LL +
Sbjct: 1348 EGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYV 1407
Query: 386 -LDDMMLLKEDESQFFSKNFVELADFGLCKKIT----------PDEMCTTRCGSEDYVSP 434
+ + ++ S N +E AD G + +T + G+ Y++P
Sbjct: 1408 DFGAAKKIANNGTRLASMNKIENAD-GEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAP 1466
Query: 435 EILLGLPYDGRI--SDAWAFGVITYALLEDRLPFDPLPGQ 472
E + G G++ D W+ G + ++ R P+ L +
Sbjct: 1467 ESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNE 1506
>YBL105c [T] KOG0694 Serine/threonine protein kinase
Length = 1151
Score = 74.7 bits (182), Expect = 3e-13
Identities = 48/143 (33%), Positives = 73/143 (50%), Gaps = 27/143 (18%)
Query: 329 MSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
M + GGDL ++ E+ +A+KY HDN +I+RD+KLEN+LL
Sbjct: 904 MEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLT----- 958
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEM-----CTTRCGSEDYVSPEILLGLPYD 443
+ +++AD+GLCK DEM +T CG+ ++++PEIL Y
Sbjct: 959 ------------PEGHIKIADYGLCK----DEMWYGNRTSTFCGTPEFMAPEILKEQEYT 1002
Query: 444 GRISDAWAFGVITYALLEDRLPF 466
+ D WAFGV+ Y +L + PF
Sbjct: 1003 KAV-DWWAFGVLLYQMLLCQSPF 1024
>SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 830
Score = 74.7 bits (182), Expect = 3e-13
Identities = 72/276 (26%), Positives = 121/276 (43%), Gaps = 71/276 (25%)
Query: 217 EIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRV 276
EIG G+F+ VY + + N + +++KS+ K+L ++
Sbjct: 19 EIGRGSFAIVYKGKHTETN---------RVISIKSVLT---------------KKLTKKL 54
Query: 277 VSSLKRELTTLISVHHPCIVKLF-AINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ +L+ E++ L + H +V+L I FI ++M YC+ G
Sbjct: 55 LENLESEISILKEIRHVHVVELIDCIKAGRFI------------------HLVMEYCSLG 96
Query: 336 DLFDLASKTK----IPN--WL---------------LTRIITE-LSVAIKYLHDNFIIHR 373
DL K + IP+ W+ L R T+ L+ A+++L +IHR
Sbjct: 97 DLSYFIRKREKFNSIPSLAWINIDHPPVYKAGLNETLVRHFTQQLASALQFLRSRSLIHR 156
Query: 374 DIKLENVLLKYTLDDMMLLKEDESQFFSKN---FVELADFGLCKKITPDEMCTTRCGSED 430
D+K +N+LL+ L E+ QF ++LADFG + + M T CGS
Sbjct: 157 DVKPQNLLLQPPPTAAYL--EEHPQFVGSPKLPMLKLADFGFARYLQTSSMAETLCGSPL 214
Query: 431 YVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
Y++PEIL YD + +D W+ G + Y + + PF
Sbjct: 215 YMAPEILRYEKYDAK-ADLWSVGAVLYEMAVGKPPF 249
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 74.7 bits (182), Expect = 3e-13
Identities = 53/166 (31%), Positives = 81/166 (47%), Gaps = 27/166 (16%)
Query: 310 EHPLYGRRKLS--ALPRCDMIMSYCTGGDLFD------LASKTKIPNWLLTRIITELSVA 361
+HP K S R +M + GGDL+ +K +E+ +A
Sbjct: 249 KHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNREVQMNKEGFSEPRARFYGSEIVLA 308
Query: 362 IKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCK-KITPDE 420
+ YLH N I++RD+KLEN+LL +++ADFGLCK +I+ +
Sbjct: 309 LGYLHANSIVYRDLKLENLLLD-----------------KDGHIKIADFGLCKEEISFGD 351
Query: 421 MCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
+T CG+ +Y++PE+L Y GR D W GV+ Y ++ RLPF
Sbjct: 352 KTSTFCGTPEYLAPEVLDDHDY-GRCVDWWGVGVVMYEMMCGRLPF 396
>7303915 [T] KOG0694 Serine/threonine protein kinase
Length = 590
Score = 74.7 bits (182), Expect = 3e-13
Identities = 67/253 (26%), Positives = 117/253 (45%), Gaps = 62/253 (24%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G G+F V L + +N +Y A+K++K + + + LLS
Sbjct: 269 LGRGHFGKVILSQLRSNN---------QYYAIKALK------KGDIIARDEVESLLSE-- 311
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
KR ++ HP +V L++ F T++H + +M Y GGDL
Sbjct: 312 ---KRIFEVANAMRHPFLVNLYSC----FQTEQHVCF-------------VMEYAAGGDL 351
Query: 338 FDLASKTKIPNWLLTRIITELS---VAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+ T + +L R + + + ++YLH+N II+RD+KL+N+LL
Sbjct: 352 M-MHIHTDV--FLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLD----------- 397
Query: 395 DESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
++ +V++ADFGLCK+ + + T CG+ ++++PE+L Y R D W G
Sbjct: 398 ------TEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYT-RAVDWWGLG 450
Query: 454 VITYALLEDRLPF 466
V+ + +L PF
Sbjct: 451 VLIFEMLVGESPF 463
>7303914 [T] KOG0694 Serine/threonine protein kinase
Length = 1284
Score = 74.7 bits (182), Expect = 3e-13
Identities = 67/253 (26%), Positives = 117/253 (45%), Gaps = 62/253 (24%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G G+F V L + +N +Y A+K++K + + + LLS
Sbjct: 963 LGRGHFGKVILSQLRSNN---------QYYAIKALK------KGDIIARDEVESLLSE-- 1005
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
KR ++ HP +V L++ F T++H + +M Y GGDL
Sbjct: 1006 ---KRIFEVANAMRHPFLVNLYSC----FQTEQHVCF-------------VMEYAAGGDL 1045
Query: 338 FDLASKTKIPNWLLTRIITELS---VAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
+ T + +L R + + + ++YLH+N II+RD+KL+N+LL
Sbjct: 1046 M-MHIHTDV--FLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLD----------- 1091
Query: 395 DESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
++ +V++ADFGLCK+ + + T CG+ ++++PE+L Y R D W G
Sbjct: 1092 ------TEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYT-RAVDWWGLG 1144
Query: 454 VITYALLEDRLPF 466
V+ + +L PF
Sbjct: 1145 VLIFEMLVGESPF 1157
>CE18058_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 416
Score = 74.7 bits (182), Expect = 3e-13
Identities = 57/205 (27%), Positives = 98/205 (47%), Gaps = 24/205 (11%)
Query: 327 MIMSYCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+++ +GG+LFD + +K + I ++ +A+++LH I+H DIK ENV+LK
Sbjct: 150 IVLELVSGGELFDHVCAKECLDEVEAAAFIKQILLAVRHLHSLHIVHLDIKPENVMLKQR 209
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
D +++ DFGL ++I P + G+ ++V+PE+ +
Sbjct: 210 GDSQ---------------IKIIDFGLSREIEPGAVVKDMVGTPEFVAPEV-VNYEALSP 253
Query: 446 ISDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIA-RCDWKWLKNADTDHPAKEI 504
+D WA GV+TY LL PF G + T S R+ ++ KN T AK+
Sbjct: 254 ATDMWAVGVVTYILLSGGSPF---LGDNRDETFSNITRVRYHFSDRYFKN--TSKHAKDF 308
Query: 505 VQNTLVRK-SERWNMDQLCNTPYIR 528
+ VR +R +++ P+IR
Sbjct: 309 IYRLFVRDVDQRATVEECLQHPWIR 333
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 74.3 bits (181), Expect = 4e-13
Identities = 65/254 (25%), Positives = 105/254 (40%), Gaps = 62/254 (24%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
+ +G G F VYL + K++ + + +L +
Sbjct: 137 RPLGKGKFGNVYLAR----------EKQSKFILALKVLFKAQLEKAG------------- 173
Query: 276 VVSSLKRELTTLISVHHPCIVKLFA-INDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
V L+RE+ + HP I++L+ +D T R +I+ Y
Sbjct: 174 VEHQLRREVEIQSHLRHPNILRLYGYFHDAT------------------RVYLILEYAPL 215
Query: 335 GDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G ++ +L +K ITEL+ A+ Y H +IHRDIK EN+LL
Sbjct: 216 GTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG---------- 265
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
S +++ADFG P TT CG+ DY+ PE++ G +D ++ D W+ G
Sbjct: 266 -------SAGELKIADFGWSVH-APSSRRTTLCGTLDYLPPEMIEGRMHDEKV-DLWSLG 316
Query: 454 VITYALLEDRLPFD 467
V+ Y L + PF+
Sbjct: 317 VLCYEFLVGKPPFE 330
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 74.3 bits (181), Expect = 4e-13
Identities = 68/244 (27%), Positives = 105/244 (42%), Gaps = 59/244 (24%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
+ +GSG ++TVY D + VA+K + K L
Sbjct: 61 ERLGSGTYATVYKAYAKKDTREV--------VAIKCVAK---------------KSLNKA 97
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
V +L E+ L + HP IV+L F D +Y +IM +C GG
Sbjct: 98 SVENLLTEIEILKGIRHPHIVQL-----KDFQWDSDNIY------------LIMEFCAGG 140
Query: 336 DLFDLASKTKI-PNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
DL +I P + + +L+ A+++LH+ I H D+K +N+LL
Sbjct: 141 DLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSS---------- 190
Query: 395 DESQFFSKNFVELADFGLCKKITP-DEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
K ++LADFG + ++P DE R GS Y++PE++ YD R+ D W+ G
Sbjct: 191 -----LEKPHLKLADFGFAQHMSPWDEKHVLR-GSPLYMAPEMVCQRQYDARV-DLWSMG 243
Query: 454 VITY 457
VI Y
Sbjct: 244 VILY 247
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 74.3 bits (181), Expect = 4e-13
Identities = 48/141 (34%), Positives = 74/141 (52%), Gaps = 20/141 (14%)
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRII-TELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
+M + GG+LF K + R E+ +A+ YLH I++RD+KLEN+LL
Sbjct: 269 VMQFANGGELFTHVRKCGTFSEPRARFYGAEIVLALGYLHRCDIVYRDMKLENLLLD--- 325
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCK-KITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
+++ADFGLCK +I+ + +T CG+ +Y++PE+L Y GR
Sbjct: 326 --------------KDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAPEVLDDHDY-GR 370
Query: 446 ISDAWAFGVITYALLEDRLPF 466
D W GV+ Y ++ RLPF
Sbjct: 371 CVDWWGVGVVMYEMMCGRLPF 391
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 74.3 bits (181), Expect = 4e-13
Identities = 64/263 (24%), Positives = 113/263 (42%), Gaps = 56/263 (21%)
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
+S++ E+ L V HP I+ +FI D + ++M Y GG L
Sbjct: 48 NSIQSEVNLLKKVQHPLIIGYI----DSFIMDN-------------QLGIVMQYAEGGTL 90
Query: 338 FDLASKTK----------IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLD 387
L + + P + T++ +A+ ++H I+HRD+K +N+L+
Sbjct: 91 ERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNRR-- 148
Query: 388 DMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRIS 447
K ++L+DFG+ K++ +T G+ +Y+SPEI PY+ + S
Sbjct: 149 --------------KTVLKLSDFGISKELGTKSAASTVIGTPNYLSPEICESRPYNQK-S 193
Query: 448 DAWAFGVITYALLEDRLPFD--PLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIV 505
D W+ G + Y LL+ FD LP + TRS + + + K +V
Sbjct: 194 DMWSLGCVLYELLQLERAFDGENLPAIVMKITRSKQNPL---------GDHVSNDVKMLV 244
Query: 506 QNTL-VRKSERWNMDQLCNTPYI 527
+N L +R ++ QL + P +
Sbjct: 245 ENLLKTHTDKRPDVSQLLSDPLV 267
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 74.3 bits (181), Expect = 4e-13
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 20/141 (14%)
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
++ + GG+LF + K + +R E++ A+ YLH+ II+RD+K EN+L L
Sbjct: 171 VLDHLNGGELFSHLQREKHFSESRSRFYAAEIACALGYLHEKNIIYRDLKPENLL----L 226
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
DD K ++ L DFGLCK+ + + +T CG+ +Y++PEI+L PYD
Sbjct: 227 DD-------------KGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKT 273
Query: 446 ISDAWAFGVITYALLEDRLPF 466
+ D W G + Y ++ PF
Sbjct: 274 V-DWWCLGSVLYEMIFGLPPF 293
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 74.3 bits (181), Expect = 4e-13
Identities = 63/256 (24%), Positives = 113/256 (43%), Gaps = 45/256 (17%)
Query: 274 SRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
S+V L+RE+ + HP I++L+ + D+ +Y +I+ Y
Sbjct: 70 SQVEHQLRREVEIQSHLRHPNILRLYG-----YFYDQKRVY------------LILEYAA 112
Query: 334 GGDLFDLASKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
G+L+ K K + L+ A+ Y H +IHRDIK EN+L+
Sbjct: 113 RGELYKDLQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIG--------- 163
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++ +++ADFG + T CG+ DY+ PE++ + +D + D W+
Sbjct: 164 --------AQGELKIADFGW--SVHTFNRRRTMCGTLDYLPPEMVESVEHDASV-DIWSL 212
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK 512
G++ Y L PF+ + + R RI + D K+ AK+++ LV++
Sbjct: 213 GILCYEFLYGVPPFEAMEHSDTYR------RIVQVDLKFPPKPIISASAKDLISQMLVKE 266
Query: 513 -SERWNMDQLCNTPYI 527
S+R + +L P+I
Sbjct: 267 SSQRLPLHKLLEHPWI 282
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 74.3 bits (181), Expect = 4e-13
Identities = 63/256 (24%), Positives = 112/256 (43%), Gaps = 45/256 (17%)
Query: 274 SRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
S+V L+RE+ + HP I++L+ + D+ +Y +I+ Y
Sbjct: 58 SQVEHQLRREVEIQSHLRHPNILRLYG-----YFYDQKRVY------------LILEYAV 100
Query: 334 GGDLFDLASKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
G+L+ K K + L+ A+ Y H +IHRDIK EN+L+
Sbjct: 101 RGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIG--------- 151
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++ +++ADFG + T CG+ DY+ PE++ + +D + D W+
Sbjct: 152 --------AQGELKIADFGW--SVHTFNRRRTMCGTLDYLPPEMVESVEHDASV-DIWSL 200
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK 512
G++ Y L PF+ +R RI + D K+ AK+++ LV++
Sbjct: 201 GILCYEFLYGVPPFE------AREHSETYKRIVQVDLKFPPKPIVSSSAKDLISQMLVKE 254
Query: 513 S-ERWNMDQLCNTPYI 527
S +R + +L P+I
Sbjct: 255 STQRLALHKLLEHPWI 270
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 74.3 bits (181), Expect = 4e-13
Identities = 61/199 (30%), Positives = 93/199 (46%), Gaps = 34/199 (17%)
Query: 270 KELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIM 329
K+L +R L+RE +HHP IV+L +D+ I +E+ Y ++
Sbjct: 48 KKLTARDFQKLEREARICRKLHHPNIVRL---HDS--IQEENYHY------------LVF 90
Query: 330 SYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDD 388
TGG+LF D+ ++ + I ++ ++ + H N ++HRD+K EN+LL
Sbjct: 91 DLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKG 150
Query: 389 MMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTR-CGSEDYVSPEILLGLPYDGRIS 447
V+LADFGL ++ D G+ Y+SPE+L PY G+
Sbjct: 151 AA--------------VKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPY-GKSV 195
Query: 448 DAWAFGVITYALLEDRLPF 466
D WA GVI Y LL PF
Sbjct: 196 DIWACGVILYILLVGYPPF 214
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 74.3 bits (181), Expect = 4e-13
Identities = 64/260 (24%), Positives = 115/260 (43%), Gaps = 61/260 (23%)
Query: 218 IGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSRVV 277
+G G F+TVY C+ + + VA+K I ++L+ + +
Sbjct: 20 LGKGGFATVYKARCLHTHQD---------VAIKMID--KKLIQGTG------------LT 56
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
+ +++E+ + HP +++L+ TF D + +Y +++ G+L
Sbjct: 57 NRVRQEVEIHSRLKHPSVLQLY-----TFFQDANYVY------------LVLELAHNGEL 99
Query: 338 FDLASKTKIP--NWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKED 395
+ P I+ ++ + YLH + I+HRDI L N+LL +
Sbjct: 100 HRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREM--------- 150
Query: 396 ESQFFSKNFVELADFGLCKKI-TPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGV 454
V++ADFGL ++ PDE T CG+ +Y+SPE++ + G +D W+ G
Sbjct: 151 --------HVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSH-GLPADVWSVGC 201
Query: 455 ITYALLEDRLPFDPLPGQSS 474
+ Y LL R PF+ QS+
Sbjct: 202 MLYTLLVGRPPFETDAVQST 221
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 73.9 bits (180), Expect = 6e-13
Identities = 53/188 (28%), Positives = 91/188 (48%), Gaps = 30/188 (15%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
+++ C G L +L + K+ R T ++ AIKY+H +IHRD+KL N+
Sbjct: 156 ILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRVIHRDLKLGNI----- 210
Query: 386 LDDMMLLKEDESQFFSKNF-VELADFGLCKKITPD-EMCTTRCGSEDYVSPEILLGLPYD 443
FF N+ +++ DFGL + + E T CG+ +Y++PE+L+G +
Sbjct: 211 -------------FFDSNYNLKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMG-KHS 256
Query: 444 GRI--SDAWAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPA 501
G D W+ GV+ YALL + PF +R +I RI D+ + ++
Sbjct: 257 GHSFEVDIWSLGVMLYALLIGKPPF------QARDVNTIYERIKCRDFSFPRDKPISDEG 310
Query: 502 KEIVQNTL 509
K ++++ L
Sbjct: 311 KILIRDIL 318
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 73.9 bits (180), Expect = 6e-13
Identities = 82/303 (27%), Positives = 131/303 (43%), Gaps = 60/303 (19%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
+E+GSG F+ V +C K A K IK R +SSS +E+
Sbjct: 17 EELGSGQFAIVR--KCRQKGTG-------KEYAAKFIKKRR---LSSSRRGVSREEI--- 61
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAI--NDTTFITDEHPLYGRRKLSALPRCDMIMSYCT 333
+RE+ L + HP I+ L I N T + +I+ +
Sbjct: 62 -----EREVNILREIRHPNIITLHDIFENKTDVV-------------------LILELVS 97
Query: 334 GGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLL 392
GG+LFD LA K + T+ + ++ + YLH I H D+K EN++L LD +
Sbjct: 98 GGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIML---LDKNV-- 152
Query: 393 KEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
++L DFG+ KI G+ ++V+PEI+ P G +D W+
Sbjct: 153 --------PNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPL-GLEADMWSI 203
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTLVRK 512
GVITY LL PF G++ + T + + D+ ++T AK+ ++ LV+
Sbjct: 204 GVITYILLSGASPF---LGETKQETLTNISAV-NYDFDEEYFSNTSELAKDFIRRLLVKD 259
Query: 513 SER 515
+R
Sbjct: 260 PKR 262
>Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase
Length = 733
Score = 73.9 bits (180), Expect = 6e-13
Identities = 63/208 (30%), Positives = 104/208 (49%), Gaps = 42/208 (20%)
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
RV S ++R++ L V+HP IVKL T E LY +I+ + G
Sbjct: 103 RVRSKMERDI--LAEVNHPFIVKLHYAFQT-----EGKLY------------LILDFLRG 143
Query: 335 GDLFDLASK-TKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
GDLF SK + + EL++A+ +LH II+RD+K EN+LL
Sbjct: 144 GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILL----------- 192
Query: 394 EDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAF 452
DE + +++ DFGL K+ I D+ + CG+ +Y++PE++ + + +D W+F
Sbjct: 193 -DE-----EGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT-QSADWWSF 245
Query: 453 GVITYALLEDRLPFDPLPGQSSRRTRSI 480
GV+ + +L LPF G+ + T ++
Sbjct: 246 GVLMFEMLTGSLPFQ---GKDRKETMAL 270
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/210 (24%), Positives = 96/210 (44%), Gaps = 26/210 (12%)
Query: 327 MIMSYCTGGDLFDLASKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYT 385
++M GG+L D + + + ++ ++ + YLH ++HRD+K N+L +
Sbjct: 484 LVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYR-- 541
Query: 386 LDDMMLLKEDESQFFSKNFVELADFGLCKKI-TPDEMCTTRCGSEDYVSPEILLGLPYDG 444
DES S + + DFG K++ + + T C + ++V+PE+L YD
Sbjct: 542 ---------DESG--SPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDA 590
Query: 445 RISDAWAFGVITYALLEDRLPF----DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHP 500
D W+ G++ Y +L PF D P + R S + ++ +W + +A
Sbjct: 591 -ACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDA----- 644
Query: 501 AKEIVQNTL-VRKSERWNMDQLCNTPYIRN 529
AK++V L V +R Q+ P++ N
Sbjct: 645 AKDVVSKMLHVDPHQRLTAMQVLKHPWVVN 674
>Hs7382496 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 545
Score = 73.6 bits (179), Expect = 7e-13
Identities = 40/141 (28%), Positives = 73/141 (51%), Gaps = 19/141 (13%)
Query: 327 MIMSYCTGGDLFDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
++M Y GG L D+ ++T + + + E A+++LH N +IHRDIK +N+LL
Sbjct: 342 VVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLG--- 398
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDE-MCTTRCGSEDYVSPEILLGLPYDGR 445
V+L DFG C +ITP++ +T G+ +++PE++ Y +
Sbjct: 399 --------------MDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPK 444
Query: 446 ISDAWAFGVITYALLEDRLPF 466
+ D W+ G++ ++E P+
Sbjct: 445 V-DIWSLGIMAIEMIEGEPPY 464
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 73.6 bits (179), Expect = 7e-13
Identities = 67/255 (26%), Positives = 118/255 (46%), Gaps = 41/255 (16%)
Query: 278 SSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDL 337
S L+ E+ L ++HHP IV L + F T E KL +MI+S
Sbjct: 618 SQLRNEVAILQNLHHPGIVNL----ECMFETPERVFVVMEKLHG-DMLEMILS------- 665
Query: 338 FDLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDES 397
+ K+++P + ++T++ VA++ LH I+H D+K ENVLL +
Sbjct: 666 ---SEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLA------------SA 710
Query: 398 QFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITY 457
+ F + V+L DFG + I + G+ Y++PE+L Y+ R D W+ GVI Y
Sbjct: 711 EPFPQ--VKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYN-RSLDMWSVGVIIY 767
Query: 458 ALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKN--ADTDHPAKEIVQNTL-VRKSE 514
L PF+ I +I + + N + A +++ N L V+ +
Sbjct: 768 VSLSGTFPFN--------EDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRK 819
Query: 515 RWNMDQLCNTPYIRN 529
R+++D+ + P++++
Sbjct: 820 RYSVDKSLSHPWLQD 834
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 73.6 bits (179), Expect = 7e-13
Identities = 51/188 (27%), Positives = 86/188 (45%), Gaps = 36/188 (19%)
Query: 280 LKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFD 339
+K E L + HP IV+L T + R +++ + GG LF
Sbjct: 179 MKAERDILTKIDHPFIVQLKYSFQTKY-----------------RLYLVLDFINGGHLFF 221
Query: 340 LASKTKIPNWLLTRIIT-ELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQ 398
+ L R+ T E+ A+ +LH+ I+HRD+K EN+L+
Sbjct: 222 QLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMD--------------- 266
Query: 399 FFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYA 458
+ V L DFGL K+ + + CG+ +Y++PEI+ G +D + +D W+ G++ Y
Sbjct: 267 --TDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHD-KAADWWSVGILLYE 323
Query: 459 LLEDRLPF 466
+L + PF
Sbjct: 324 MLTGKPPF 331
>At1g60940 [T] KOG0583 Serine/threonine protein kinase
Length = 361
Score = 73.6 bits (179), Expect = 7e-13
Identities = 68/306 (22%), Positives = 117/306 (38%), Gaps = 62/306 (20%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
++ +K+IG+GNF L +K +EL+ + KY
Sbjct: 3 KYELVKDIGAGNFGVARLMR---------------------VKNSKELV------AMKYI 35
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
E ++ ++ RE+ S+ HP I++ + +T H + M
Sbjct: 36 ERGPKIDENVAREIINHRSLRHPNIIRFKEV----VLTPTH-------------IAIAME 78
Query: 331 YCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
Y GG+LF+ + S + +L + Y H I HRD+KLEN LL +
Sbjct: 79 YAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPR 138
Query: 390 MLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDA 449
+ ++ DFG K M + G+ Y++PE+L YDG+++D
Sbjct: 139 L---------------KICDFGYSKSSLLHSMPKSTVGTPAYIAPEVLSRGEYDGKMADV 183
Query: 450 WAFGVITYALLEDRLPFDPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNTL 509
W+ GV Y +L PF+ + + + RI +K K ++
Sbjct: 184 WSCGVTLYVMLVGAYPFE--DQEDPKNFKKTIQRIMAVKYKIPDYVHISQDCKHLLSRIF 241
Query: 510 VRKSER 515
V S +
Sbjct: 242 VTNSNK 247
>7297611 [T] KOG0614 cGMP-dependent protein kinase
Length = 1003
Score = 73.6 bits (179), Expect = 7e-13
Identities = 45/140 (32%), Positives = 70/140 (49%), Gaps = 19/140 (13%)
Query: 328 IMSYCTGGDLFDLASKTKIPNWLLTRIITELSV-AIKYLHDNFIIHRDIKLENVLLKYTL 386
+M C GGD++ + SK + + + I V A YLH + I+RD+K EN++L
Sbjct: 769 LMEACMGGDVWTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLG--- 825
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRI 446
+ + +L DFG K + +E T G+ +YV+PEI+L +D R
Sbjct: 826 --------------TDGYCKLVDFGFAKFVRQNEKTNTFAGTPEYVAPEIILDRGHD-RA 870
Query: 447 SDAWAFGVITYALLEDRLPF 466
D WA G++ Y LL + PF
Sbjct: 871 VDYWALGILVYELLVGKTPF 890
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 73.6 bits (179), Expect = 7e-13
Identities = 56/211 (26%), Positives = 96/211 (44%), Gaps = 43/211 (20%)
Query: 282 RELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGGDLFDLA 341
+E+T S++HP IVK + D +Y +++ C + +L
Sbjct: 72 QEITIHRSLNHPNIVKFH-----NYFEDSQNIY------------IVLELCKKRSMMELH 114
Query: 342 SKTK-IPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFF 400
+ K I + I ++ +KYLHDN IIHRD+KL N+ L L
Sbjct: 115 KRRKSITEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLL-------------- 160
Query: 401 SKNFVELADFGLCKKITPD-EMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFGVITYAL 459
V++ DFGL +I + E T CG+ +Y++PEIL + + D W+ G + Y L
Sbjct: 161 ---HVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILTKKGHSFEV-DIWSIGCVMYTL 216
Query: 460 LEDRLPFDPLPGQSSRRTRSIAHRIARCDWK 490
L + PF+ ++ + +I +C+++
Sbjct: 217 LVGQPPFE------TKTLKDTYSKIKKCEYR 241
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 73.6 bits (179), Expect = 7e-13
Identities = 45/141 (31%), Positives = 69/141 (48%), Gaps = 20/141 (14%)
Query: 328 IMSYCTGGDLF-DLASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTL 386
++ + GG+LF L + P E++ A+ YLH I++RD+K EN+L+
Sbjct: 121 VLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILVD--- 177
Query: 387 DDMMLLKEDESQFFSKNFVELADFGLCKK-ITPDEMCTTRCGSEDYVSPEILLGLPYDGR 445
S V L DFGLCK+ I + TT CG+ +Y++PE++ PYD
Sbjct: 178 --------------SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNT 223
Query: 446 ISDAWAFGVITYALLEDRLPF 466
+ D W G + Y +L PF
Sbjct: 224 V-DWWCLGAVLYEMLYGLPPF 243
>7291742_1 [T] KOG0612 Rho-associated coiled-coil containing protein kinase
Length = 1539
Score = 73.6 bits (179), Expect = 7e-13
Identities = 52/148 (35%), Positives = 68/148 (45%), Gaps = 25/148 (16%)
Query: 327 MIMSYCTGGDLFDLASK--TKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKY 384
++M Y GGDL L SK K+P + ITE+ +AI +H +HRDIK +NVLL
Sbjct: 175 LVMDYYCGGDLLTLLSKFEDKLPEDMAKFYITEMILAINSIHQIRYVHRDIKPDNVLLD- 233
Query: 385 TLDDMMLLKEDESQFFSKNFVELADFGLCKKITPD--EMCTTRCGSEDYVSPEILL---- 438
+ V LADFG C ++ D G+ DY+SPEIL
Sbjct: 234 ----------------KRGHVRLADFGSCLRLDKDGTVQSNVAVGTPDYISPEILRAMED 277
Query: 439 GLPYDGRISDAWAFGVITYALLEDRLPF 466
G G D W+ GV Y +L PF
Sbjct: 278 GKGRYGTECDWWSLGVCMYEMLYGETPF 305
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 73.2 bits (178), Expect = 1e-12
Identities = 51/193 (26%), Positives = 90/193 (46%), Gaps = 38/193 (19%)
Query: 275 RVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTG 334
R + E L+ + HP IVK++A D + LY MIM + G
Sbjct: 2 RQTQHVHNEKRVLLQLKHPFIVKMYASEK-----DSNHLY------------MIMEFVPG 44
Query: 335 GDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLK 393
G++F L + N + +E+ A++Y+H I++RD+K EN++L
Sbjct: 45 GEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLS---------- 94
Query: 394 EDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDAWAFG 453
+ +++ADFG K++ + T CG+ DY++PE L ++ + D WA G
Sbjct: 95 -------KEGHIKMADFGFAKELR--DRTYTICGTPDYLAPESLARTGHNKGV-DWWALG 144
Query: 454 VITYALLEDRLPF 466
++ Y ++ + PF
Sbjct: 145 ILIYEMMVGKPPF 157
>At5g63650 [T] KOG0583 Serine/threonine protein kinase
Length = 360
Score = 73.2 bits (178), Expect = 1e-12
Identities = 74/328 (22%), Positives = 132/328 (39%), Gaps = 66/328 (20%)
Query: 211 QWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYK 270
++ +K++G+GNF L L++ K +EL+ + KY
Sbjct: 3 KYEVVKDLGAGNFGVARL---------------LRH------KETKELV------AMKYI 35
Query: 271 ELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMS 330
E ++ ++ RE+ S+ HP I++ + +T H ++M
Sbjct: 36 ERGRKIDENVAREIINHRSLRHPNIIRFKEV----ILTPTH-------------LAIVME 78
Query: 331 YCTGGDLFD-LASKTKIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDM 389
Y +GG+LF+ + + + +L + Y H I HRD+KLEN LL + +
Sbjct: 79 YASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPL 138
Query: 390 MLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRISDA 449
+ ++ DFG K + G+ Y++PE+L YDG+ +D
Sbjct: 139 L---------------KICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADV 183
Query: 450 WAFGVITYALLEDRLPF-DPLPGQSSRRTRSIAHRIARCDWKWLKNADTDHPAKEIVQNT 508
W+ GV Y +L PF DP R R RI +K + ++
Sbjct: 184 WSCGVTLYVMLVGGYPFEDP---DDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRI 240
Query: 509 LVRKS-ERWNMDQLCNTP-YIRNIIDKL 534
V S +R + ++ P Y++N+ +L
Sbjct: 241 FVTNSAKRITLKEIKKHPWYLKNLPKEL 268
>At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta
and related serine/threonine protein kinases
Length = 407
Score = 73.2 bits (178), Expect = 1e-12
Identities = 69/282 (24%), Positives = 116/282 (40%), Gaps = 70/282 (24%)
Query: 196 IIRGYMANTPNHISFQWSKIKEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYP 255
+IRG N I+ ++ ++ +IGSG++ V LY D +Y A+K+
Sbjct: 94 LIRGEDENGDKTIN-EYVRVCKIGSGSYGKVVLYRSTLDG---------QYYAIKAFHKS 143
Query: 256 RELLMSSSPSSPKYKELLSRVVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYG 315
L + +PS ++L RE+ + + HP IV L + D
Sbjct: 144 HLLRLRVAPSETAMSDVL--------REVMIMKILEHPNIVNLIEVIDD----------- 184
Query: 316 RRKLSALPRCD---MIMSYCTGGDLFD-------LASKTKIPNWLLTRIITELSVAIKYL 365
P D M++ Y G ++D L KT + + ++ + YL
Sbjct: 185 -------PETDHFYMVLEYVDGKWVYDGSGPPGALGEKTA------RKYLRDIVTGLMYL 231
Query: 366 HDNFIIHRDIKLENVLLKYTLDDMMLLKEDESQFFSKNFVELADFGLCKKITPDEMCTTR 425
H + +IH DIK +N+L+ S V++ DF + + D+ R
Sbjct: 232 HAHDVIHGDIKPDNLLVT-----------------SSGTVKIGDFSVSQVFKDDDDQLRR 274
Query: 426 C-GSEDYVSPEILLGLPYDGRISDAWAFGVITYALLEDRLPF 466
G+ + +PE LG+ Y GR +D WA GV Y ++ + PF
Sbjct: 275 SPGTPVFTAPECCLGITYSGRAADTWAVGVTLYCMILGQYPF 316
>At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 691
Score = 73.2 bits (178), Expect = 1e-12
Identities = 55/232 (23%), Positives = 106/232 (44%), Gaps = 49/232 (21%)
Query: 216 KEIGSGNFSTVYLYECIDDNLNINLNPELKYVAVKSIKYPRELLMSSSPSSPKYKELLSR 275
++IGSG+FS V+ E +++ ++ +E+ M+ L +
Sbjct: 24 RQIGSGSFSVVW---------------EGRHLVHGTVVAIKEIAMA---------RLNKK 59
Query: 276 VVSSLKRELTTLISVHHPCIVKLFAINDTTFITDEHPLYGRRKLSALPRCDMIMSYCTGG 335
+ SL E+ L ++HP I++ + + A + ++++ YC GG
Sbjct: 60 LQESLMSEIIILRKINHPNIIRFIDM-----------------IEAPGKINLVLEYCKGG 102
Query: 336 DLFDLASKT-KIPNWLLTRIITELSVAIKYLHDNFIIHRDIKLENVLLKYTLDDMMLLKE 394
DL K +P + +L+ ++ L DN IIHRD+K + +L + +++L +
Sbjct: 103 DLSMYIHKHGSVPEATAKHFMLQLAAGLQVLRDNNIIHRDLKPQ--VLSFLKQNLLLSTD 160
Query: 395 DESQFFSKNFVELADFGLCKKITPDEMCTTRCGSEDYVSPEILLGLPYDGRI 446
D +++ADFG + + P + T CGS Y++PEI+ YD ++
Sbjct: 161 DNDAA-----LKIADFGFARSLQPRGLAETLCGSPLYMAPEIMQLQKYDAKL 207
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,883,928
Number of Sequences: 60738
Number of extensions: 1525486
Number of successful extensions: 8563
Number of sequences better than 1.0e-05: 788
Number of HSP's better than 0.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 711
Number of HSP's that attempted gapping in prelim test: 6789
Number of HSP's gapped (non-prelim): 934
length of query: 541
length of database: 30,389,216
effective HSP length: 111
effective length of query: 430
effective length of database: 23,647,298
effective search space: 10168338140
effective search space used: 10168338140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)