ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3742 good CE KOG0453 Amino acid transport and metabolism Aconitase/homoaconitase (aconitase superfamily)
r_klactIII3742 good CE KOG0453 Energy production and conversion Aconitase/homoaconitase (aconitase superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3742 1316235 1318313 693
(693 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR234w [CE] KOG0453 Aconitase/homoaconitase (aconitase superfam... 1094 0.0
SPAC343.16 [CE] KOG0453 Aconitase/homoaconitase (aconitase super... 826 0.0
SPAC9E9.03 [E] KOG0454 3-isopropylmalate dehydratase (aconitase ... 194 4e-49
YGL009c [E] KOG0454 3-isopropylmalate dehydratase (aconitase sup... 177 4e-44
At4g13430 [E] KOG0454 3-isopropylmalate dehydratase (aconitase s... 161 3e-39
YLR304c [CE] KOG0453 Aconitase/homoaconitase (aconitase superfam... 152 2e-36
Hs4501867 [CE] KOG0453 Aconitase/homoaconitase (aconitase superf... 150 6e-36
SPBP4H10.15 [CE] KOG0453 Aconitase/homoaconitase (aconitase supe... 144 6e-34
CE25005 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfam... 143 1e-33
YJL200c [CE] KOG0453 Aconitase/homoaconitase (aconitase superfam... 142 2e-33
SPAC24C9.06c [CE] KOG0453 Aconitase/homoaconitase (aconitase sup... 134 4e-31
7298762 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfam... 132 2e-30
7299398 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfam... 130 5e-30
7300911 [AJ] KOG0452 RNA-binding translational regulator IRP (ac... 106 1e-22
At4g26970 [AJ] KOG0452 RNA-binding translational regulator IRP (... 103 9e-22
Hs8659555 [AJ] KOG0452 RNA-binding translational regulator IRP (... 100 1e-20
7299336 [AJ] KOG0452 RNA-binding translational regulator IRP (ac... 99 2e-20
At4g35830 [AJ] KOG0452 RNA-binding translational regulator IRP (... 99 3e-20
CE03812 [AJ] KOG0452 RNA-binding translational regulator IRP (ac... 97 6e-20
At2g05710 [AJ] KOG0452 RNA-binding translational regulator IRP (... 96 2e-19
Hs17478037 [AJ] KOG0452 RNA-binding translational regulator IRP ... 93 2e-18
At3g58990 [E] KOG0454 3-isopropylmalate dehydratase (aconitase s... 54 6e-07
At2g43090 [E] KOG0454 3-isopropylmalate dehydratase (aconitase s... 54 6e-07
At2g43100 [E] KOG0454 3-isopropylmalate dehydratase (aconitase s... 54 1e-06
>YDR234w [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 693
Score = 1094 bits (2830), Expect = 0.0
Identities = 538/687 (78%), Positives = 598/687 (86%), Gaps = 3/687 (0%)
Query: 8 RMFSTSRALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVALKFM 67
R F +SRA GQN+TEKIVQ +AV LPEGK V SGDYVSIKPAHCMSHDNSWPVALKFM
Sbjct: 9 RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
Query: 68 GLGASTIKNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQIMIE 127
GLGA+ IKNP Q+V TLDHD+QNKSEKNLTKYKNIENFAKKH ID YPAGRGIGHQIMIE
Sbjct: 69 GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
Query: 128 EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGEL 187
EGYAFPL MTVASDSHSNTYGG+G+LGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG+L
Sbjct: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
Query: 188 PAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFP 247
P G+SGKDIIVALCG+FN DQVLNHAIEFTGDSL+ +PID+RLTIANMTTEWGALSGLFP
Sbjct: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
Query: 248 VDNVLLDFYRNRLTKVG-NNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTH 306
VD L+D+Y+NRL K+G NNHPRIN I L+ K+ +AD DA YAKKLIIDL+TLTH
Sbjct: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
Query: 307 YVSGPNSVKISSTVDDLSKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVA 366
YVSGPNSVK+S+TV DLS+QDIK+NKAYLVSCTNSRLSDL+SAA+VVCP+GD+N+V+KVA
Sbjct: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
Query: 367 EGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQVGISAT 426
GVEFY+ +GAW+KLL AGC+PLP+GCGPCIGLG GLLE G+VGISAT
Sbjct: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
Query: 427 NRNFKGRMGSKDALAYLASPSVVAASAILGKIGSPAEVLGTKDPNFTGVVATVEDAPATS 486
NRNFKGRMGSKDALAYLASP+VVAASA+LGKI SPAEVL T + F+GV + + P
Sbjct: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
Query: 487 ADGKDVADESGASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYTYQDDVPKETMA 546
+ A SVEILEGFP E SGELVLCDADNINTDGIYPGKYTYQDDVPKE MA
Sbjct: 489 EEVN--AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMA 546
Query: 547 KVCMENYDPDFQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRN 606
+VCMENYD +F+TK +PGDI++SGFNFGTGSSREQAATA+LAKGI LVVSGSFGNIF RN
Sbjct: 547 QVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
Query: 607 SINNALLTLEIPALINMLRDRYKDAPKELTRRTGWFLKWDVSQAKVYVTEGSVNGPIVLE 666
SINNALLTLEIPALI LR++Y+ APKELTRRTGWFLKWDV+ AKV VTEGS++GP++LE
Sbjct: 607 SINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILE 666
Query: 667 QKVGELGKNLQEIIVKGGLESWVKSQL 693
QKVGELGKNLQEIIVKGGLE WVKSQL
Sbjct: 667 QKVGELGKNLQEIIVKGGLEGWVKSQL 693
>SPAC343.16 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 721
Score = 826 bits (2134), Expect = 0.0
Identities = 416/677 (61%), Positives = 501/677 (73%), Gaps = 23/677 (3%)
Query: 20 QNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVALKFMGLGASTIKNPRQ 79
Q +TEKIVQ+ A +PE K V SGDYV+IKP HCMSHDNSWPVALKFMG+GA + + RQ
Sbjct: 61 QTITEKIVQKFAQNIPENKYVRSGDYVTIKPKHCMSHDNSWPVALKFMGIGAKKVFDNRQ 120
Query: 80 VVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQIMIEEGYAFPLTMTVA 139
+V TLDHDVQNKSE NL KYKNIE+FAK GIDFYPAGRGIGHQIM+E+GYA P +M VA
Sbjct: 121 IVCTLDHDVQNKSEANLRKYKNIESFAKGQGIDFYPAGRGIGHQIMVEQGYAMPGSMAVA 180
Query: 140 SDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVA 199
SDSHSNTYGG+G LGTPIVRTDAAAIWATGQTWWQIPP+A+V L G+LP G+SGKDIIV+
Sbjct: 181 SDSHSNTYGGVGCLGTPIVRTDAAAIWATGQTWWQIPPIARVNLVGQLPKGLSGKDIIVS 240
Query: 200 LCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNR 259
LCG FN D+VLNHAIEF G+ L+ + I+ RLTIANMTTEWGALSGLFP D LL +Y +R
Sbjct: 241 LCGAFNHDEVLNHAIEFYGEGLNSLSIESRLTIANMTTEWGALSGLFPTDEKLLAWYEDR 300
Query: 260 LTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVSGPNSVKISST 319
L +G NHPR+N ++ + K+ + AD A YAK LI+DLSTL+ VSGPNSVK+ ++
Sbjct: 301 LKFLGPNHPRVNRETLDAI--KASPILADEGAFYAKHLILDLSTLSPAVSGPNSVKVYNS 358
Query: 320 VDDLSKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVAEGVEFYIXXXXXX 379
L K+DI + KAYLVSCTN RLSD+ AA V + KVA+GVEFY+
Sbjct: 359 AATLEKKDILIKKAYLVSCTNGRLSDIHDAAETV-------KGKKVADGVEFYVGAASSE 411
Query: 380 XXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQVGISATNRNFKGRMGSKDA 439
G WQ L+++G LPAGCGPCIGLGTGLL++G+VGISATNRNFKGRMGS++A
Sbjct: 412 VEAAAQKNGDWQTLIDSGARTLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGRMGSREA 471
Query: 440 LAYLASPSVVAASAILGKIGSPAEVLGTKDPNFTGVVATVEDAPATSADGKDVADES--- 496
LAYLASP+VVAASAI GKI +P F V+ V T K A +S
Sbjct: 472 LAYLASPAVVAASAIAGKIVAP--------EGFKNAVSLVSAVDITDKVNKQTASKSSTE 523
Query: 497 GASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYTYQDDVPKETMAKVCMENYDPD 556
I++GFPS ++GE+V CDADN+NTDGIYPG+YTY+DD+ KE MAKVCMENYD +
Sbjct: 524 AVDSETAIIDGFPSIVAGEIVFCDADNLNTDGIYPGRYTYRDDITKEEMAKVCMENYDSE 583
Query: 557 FQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNALLTLE 616
F K DIL+SGFNFGTGSSREQAATAIL++GI LVV GSF +IF RNSINNALL ++
Sbjct: 584 FGKKTKKDDILVSGFNFGTGSSREQAATAILSRGIPLVVGGSFSDIFKRNSINNALLAIQ 643
Query: 617 IPALINMLRDRYKDAPKELTRRTGWFLKWDVSQAKVYVTEGSVNGPIVLEQKVGELGKNL 676
+P L+ LR + + KELTRRTGW LKWDV ++ V VT + K+GELG ++
Sbjct: 644 LPDLVQKLRTAFANESKELTRRTGWHLKWDVRKSTVTVTTSDNK---EMSWKIGELGNSV 700
Query: 677 QEIIVKGGLESWVKSQL 693
Q + V+GGLE WVK ++
Sbjct: 701 QSLFVRGGLEGWVKHEI 717
>SPAC9E9.03 [E] KOG0454 3-isopropylmalate dehydratase (aconitase superfamily)
Length = 758
Score = 194 bits (493), Expect = 4e-49
Identities = 174/698 (24%), Positives = 309/698 (43%), Gaps = 101/698 (14%)
Query: 13 SRALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVALKFMGLGAS 72
S ++ + + + +K+ H V L E T + Y+ + H+ + P A + +
Sbjct: 2 SPSVASPKTLYDKVWDSHVVDLQEDGTCLL--YID----RHLIHEVTSPQAFEGLRTAGR 55
Query: 73 TIKNPRQVVNTLDHDVQNKSEKNL-------------TKYKNIENFAKKHGIDFYPAG-- 117
+++P + T+DH++ K++ T+ +EN K+ G+ +Y
Sbjct: 56 KVRHPELALATVDHNIPTDPRKDMKDIASFIHQPDSRTQVLALENNIKEFGLTYYGMNDR 115
Query: 118 -RGIGHQIMIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIP 176
+GI H I E+G+ P T V DSH++T+G GAL I ++ + AT +
Sbjct: 116 RQGIVHVIGPEQGFTLPGTTLVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTILQRKS 175
Query: 177 PVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMT 236
++ + G+LP GI+ KD+I+ + GV IEF G++++ + ++ R+++ NM+
Sbjct: 176 KNMRIRVNGKLPEGIASKDLILHIIGVIGTAGGTGSVIEFCGEAIEGLSMEARMSMCNMS 235
Query: 237 TEWGALSGLFPVDNVLLDFYRNR-LTKVGNNHPRINEARINELQAKSDSLQADPDAKYAK 295
E GA +G+ D ++ +NR L G++ + A +L++D +AKY
Sbjct: 236 IEAGARAGMIAPDATTFEYVKNRPLAPKGDDW--------EQAVAYWKTLRSDENAKYDI 287
Query: 296 KLIID----LSTLTHYVSGPNSVKISSTVDDLS--KQDIK-------------------- 329
++ I+ L T+T S + + I+ + D + K +++
Sbjct: 288 EVEINAADVLPTVTWGTSPQDVIPINGNIPDPAHVKDNVRAASIQRSLEYMGLKPNTSIV 347
Query: 330 ---VNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVAEGV-EFYIXXXXXXXXXXXX 385
++K ++ SCTNSR+ DL AA VV + KVA V + I
Sbjct: 348 SYPIDKVFIGSCTNSRIEDLRLAAAVV-------KGRKVAANVKDAMIVPGSGLVKKMAE 400
Query: 386 XTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQVGISATNRNFKGRMGSKDALAYLAS 445
G Q + AG AGC C+G+ L+ + S +NRNF+GR G+K +L S
Sbjct: 401 AEGLDQIFIEAGFDWREAGCSMCLGMNPDQLKPYERCASTSNRNFEGRQGAK-GRTHLVS 459
Query: 446 PSVVAASAILGKIGSPAEVLGTKDPNFTGVVATVEDAPATSADGKDVADESGASGSVEIL 505
P++ AA+AI G + + E G ++ P+ +G A+ +V
Sbjct: 460 PAMAAAAAIKGHLCNVREFFGDVSNGSPSIITNKNYDPSHDVEGDIGLSVDDATDAVTDA 519
Query: 506 EGFPSEISGELVLCDAD-----------------NINTDGIYPGKYTYQDDVPKETMAKV 548
+G + ++G + A N++TD I P ++ + + + +
Sbjct: 520 DGIATNVAGSVSSGSAGIPKFTVVEGIAAPLPMANVDTDKIIPKQFL--KTIKRTGLGQF 577
Query: 549 CME--NYD------PDFQTKANP---GDILISGFNFGTGSSREQAATAILAKGIKLVVSG 597
YD PDF P +L++ NFG GSSRE A A+ GI+++++
Sbjct: 578 AFYEIRYDADGKEIPDFVLNREPYRHATVLVAHDNFGCGSSREHAPWALNDFGIRVIIAP 637
Query: 598 SFGNIFFRNSINNALLTLEIPALINMLRDRYKDAPKEL 635
SF +IFF N N + L IP I + D K A ++
Sbjct: 638 SFADIFFNNCFKNGM--LPIPTPIEQVNDMMKAAENQV 673
>YGL009c [E] KOG0454 3-isopropylmalate dehydratase (aconitase superfamily)
Length = 779
Score = 177 bits (450), Expect = 4e-44
Identities = 170/687 (24%), Positives = 297/687 (42%), Gaps = 116/687 (16%)
Query: 20 QNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVALKFMGLGASTIKNPRQ 79
+ + +K+ H V E +G ++ H + H+ + P A + + ++
Sbjct: 10 RTLYDKVFDAHVVHQDE-----NGSFLLYIDRHLV-HEVTSPQAFEGLENAGRKVRRVDC 63
Query: 80 VVNTLDHDVQNKSEKNLT-------------KYKNIENFAKKHGIDFY---PAGRGIGHQ 123
+ T+DH++ +S KN + K +EN K+ G+ ++ A +GI H
Sbjct: 64 TLATVDHNIPTESRKNFKSLDTFIKQTDSRLQVKTLENNVKQFGVPYFGMSDARQGIVHT 123
Query: 124 IMIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVEL 183
I EEG+ P T V DSH++T+G G+L I ++ + AT ++ +
Sbjct: 124 IGPEEGFTLPGTTVVCGDSHTSTHGAFGSLAFGIGTSEVEHVLATQTIIQAKSKNMRITV 183
Query: 184 KGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALS 243
G+L GI+ KD+I+ + G+ IEF G++++ + ++ R+++ NM E GA +
Sbjct: 184 NGKLSPGITSKDLILYIIGLIGTAGGTGCVIEFAGEAIEALSMEARMSMCNMAIEAGARA 243
Query: 244 GLFPVDNVLLDFYRNR-LTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIID-- 300
G+ D + + R L G A + A +L+ D AK+ ++ I+
Sbjct: 244 GMIKPDETTFQYTKGRPLAPKG--------AEWEKAVAYWKTLKTDEGAKFDHEINIEAV 295
Query: 301 --LSTLTHYVSGPNSVKISSTVDDLSK-------------------------QDIKVNKA 333
+ T+T S +++ I+ +V D + IKV+K
Sbjct: 296 DVIPTITWGTSPQDALPITGSVPDPKNVTDPIKKSGMERALAYMGLEPNTPLKSIKVDKV 355
Query: 334 YLVSCTNSRLSDLESAANVVCPSGDINQVHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKL 393
++ SCTN R+ DL SAA VV + K+A ++ + K+
Sbjct: 356 FIGSCTNGRIEDLRSAAAVV-------RGQKLASNIKLAMVVPGSGLVKKQAEAEGLDKI 408
Query: 394 LN-AGCLPLPAGCGPCIGLGTGLLEEGQVGISATNRNFKGRMGSKDALAYLASPSVVAAS 452
AG AGC C+G+ +L+ + S +NRNF+GR G+ +L SP++ AA+
Sbjct: 409 FQEAGFEWREAGCSICLGMNPDILDAYERCASTSNRNFEGRQGALSR-THLMSPAMAAAA 467
Query: 453 AILGKI-------------GSPAEVLGTKDPNFTGVVA-------TVEDAPATSADG--K 490
I G SP + ++D A EDAP A+ K
Sbjct: 468 GIAGHFVDIREFEYKDQDQSSPKVEVTSEDEKELESAAYDHAEPVQPEDAPQDIANDELK 527
Query: 491 DV---ADESGASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYT------------ 535
D+ +D++ A S ++ F + + G D N++TD I P ++
Sbjct: 528 DIPVKSDDTPAKPSSSGMKPFLT-LEGISAPLDKANVDTDAIIPKQFLKTIKRTGLKKGL 586
Query: 536 -YQDDVPKETMAKVCMENYDPDFQTKANPGD----ILISGFNFGTGSSREQAATAILAKG 590
Y+ K+ K + + DF P ++++G NFG GSSRE A A+ G
Sbjct: 587 FYEWRFRKDDQGK----DQETDFVLNVEPWREAEILVVTGDNFGCGSSREHAPWALKDFG 642
Query: 591 IKLVVSGSFGNIFFRNSINNALLTLEI 617
IK +++ S+G+IF+ NS N LL + +
Sbjct: 643 IKSIIAPSYGDIFYNNSFKNGLLPIRL 669
>At4g13430 [E] KOG0454 3-isopropylmalate dehydratase (aconitase superfamily)
Length = 509
Score = 161 bits (408), Expect = 3e-39
Identities = 129/482 (26%), Positives = 215/482 (43%), Gaps = 46/482 (9%)
Query: 5 QRLRMFSTSRALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVAL 64
Q+ R T+ ++ G MTEKI+ R + E VV GD + + M+HD P A
Sbjct: 52 QKDRSPGTTGSVKTGMTMTEKILARAS----EKSLVVPGDNIWVNVDVLMTHDVCGPGAF 107
Query: 65 KFMGLG---ASTIKNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFY------- 114
+ + +P ++V DH + ++ + ++ I ++
Sbjct: 108 GIFKREFGEKAKVWDPEKIVVIPDHYIFTADKRANRNVDIMREHCREQNIKYFYDITDLG 167
Query: 115 -----PAGRGIGHQIMIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATG 169
P +G+ H + +EG+ P + + +DSH+ T G G T I TDA + TG
Sbjct: 168 NFKANPDYKGVCHVALAQEGHCRPGEVLLGTDSHTCTAGAFGQFATGIGNTDAGFVLGTG 227
Query: 170 QTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYR 229
+ ++PP + L GE+P+ + KD+I+ + G + +EF+G +++ + ++ R
Sbjct: 228 KILLKVPPTMRFILDGEMPSYLQAKDLILQIIGEISVAGATYKTMEFSGTTIESLSMEER 287
Query: 230 LTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQAKSDSLQADP 289
+T+ NM E G +G+ P D L++ EA I + +D
Sbjct: 288 MTLCNMVVEAGGKNGVIPPDATTLNYV---------------EACILSCFL---PVYSDG 329
Query: 290 DAKYAKKLIIDLSTLTHYVSGPNSVKISSTVDDLSKQDIKVNKAYLVSCTNSRLSDLESA 349
+A + D+S L V+ P+S + + +D+K+++ Y+ SCT + D +A
Sbjct: 330 NASFVADYRFDVSKLEPVVAKPHSPDNRALAREC--KDVKIDRVYIGSCTGGKTEDFMAA 387
Query: 350 ANVVCPSGDINQV--HKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGC-LPLPAGCG 406
A + +G +V V + ++ T A Q AGC P CG
Sbjct: 388 AKLFHAAGRKVKVPTFLVPATQKVWMDVYALPVPGAGGKTCA-QIFEEAGCDTPASPSCG 446
Query: 407 PCIGLGT---GLLEEGQVGISATNRNFKGRMGSKDALAYLASPSVVAASAILGKIGSPAE 463
C+G L E QV +S TNRNF GRMG K+ YLASP AASA+ G++ P E
Sbjct: 447 ACLGGPADTYARLNEPQVCVSTTNRNFPGRMGHKEGQIYLASPYTAAASALTGRVADPRE 506
Query: 464 VL 465
L
Sbjct: 507 FL 508
>YLR304c [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 778
Score = 152 bits (383), Expect = 2e-36
Identities = 177/660 (26%), Positives = 285/660 (42%), Gaps = 86/660 (13%)
Query: 24 EKIVQRHAVGLPEGKTVVSG-DYVSIKPAHCMSHDNSWPVA-LKFMGLGASTIKNPRQVV 81
EKI+ H + P G+ + G Y+ ++P D + +A L+FM G + P V
Sbjct: 63 EKILYGH-LDDPHGQDIQRGVSYLKLRPDRVACQDATAQMAILQFMSAGLPQVAKP--VT 119
Query: 82 NTLDHDVQNK--SEKNLTK--------YKNIENFAKKHGIDFYPAGRGIGHQIMIEEGYA 131
DH +Q + EK+L + Y + + K+ + F+ G GI HQI++E YA
Sbjct: 120 VHCDHLIQAQVGGEKDLKRAIDLNKEVYDFLASATAKYNMGFWKPGSGIIHQIVLEN-YA 178
Query: 132 FPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTW-WQIPPVAQVELKGELPAG 190
FP + + +DSH+ GG+G L + DA + A G+ W + P + V+L G++
Sbjct: 179 FPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMA-GRPWELKAPKILGVKLTGKMNGW 237
Query: 191 ISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVDN 250
S KDII+ L G+ +E+ GD +D TI NM E GA + +FP +
Sbjct: 238 TSPKDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGMGTICNMGAEIGATTSVFPFNK 297
Query: 251 VLLDFYRNRLTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVSG 310
++++ L G R A +L K D L AD DA+Y + + IDL+TL Y++G
Sbjct: 298 SMIEY----LEATG----RGKIADFAKLYHK-DLLSADKDAEYDEVVEIDLNTLEPYING 348
Query: 311 PNSVKISSTVDDL------SKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHK 364
P + +++ V + + + V + SCTNS D+ +A++V + H
Sbjct: 349 PFTPDLATPVSKMKEVAVANNWPLDVRVGLIGSCTNSSYEDMSRSASIVKDAA----AHG 404
Query: 365 VAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGL-LEEGQVG- 422
+ F + G + G + L CGPCIG +++G
Sbjct: 405 LKSKTIFTVTPGSEQIRATIERDGQLETFKEFGGIVLANACGPCIGQWDRRDIKKGDKNT 464
Query: 423 -ISATNRNFKGRM-GSKDALAYLASPSVVAASAILG--KIGSPAEVLGTKD--------P 470
+S+ NRNF R G+ A++ASP +V A AI G + + L KD P
Sbjct: 465 IVSSYNRNFTSRNDGNPQTHAFVASPELVTAFAIAGDLRFNPLTDKLKDKDGNEFMLKPP 524
Query: 471 NFTGVVATVEDA-----PATSADGKDV-ADESGASGSVEILEGFP----SEISGELVLCD 520
+ G+ DA A AD V S S +++L+ F + +L
Sbjct: 525 HGDGLPQRGYDAGENTYQAPPADRSTVEVKVSPTSDRLQLLKPFKPWDGKDAKDMPILIK 584
Query: 521 A------DNINTDGIYPGKYTYQDDVPKETMAKV---------CMEN-YDPDFQ----TK 560
A D+I+ G + + +++ M C++N Y +++ T
Sbjct: 585 AVGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAENKKANCVKNVYTGEYKGVPDTA 644
Query: 561 ANPGD-----ILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNALLTL 615
+ D ++I NFG GSSRE AA G +++ SF I N LL L
Sbjct: 645 RDYRDQGIKWVVIGDENFGEGSSREHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPL 704
>Hs4501867 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 780
Score = 150 bits (379), Expect = 6e-36
Identities = 172/662 (25%), Positives = 279/662 (41%), Gaps = 87/662 (13%)
Query: 22 MTEKIVQRHAVGLPEGKTVVSG-DYVSIKPAHCMSHDNSWPVA-LKFMGLGASTIKNPRQ 79
++EKIV H + P + + G Y+ ++P D + +A L+F+ G S + P
Sbjct: 65 LSEKIVYGH-LDDPASQEIERGKSYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPST 123
Query: 80 VVNTLDH--DVQNKSEKNLTKYKNIE----NF----AKKHGIDFYPAGRGIGHQIMIEEG 129
+ DH + Q EK+L + K+I NF K+G+ F+ G GI HQI++E
Sbjct: 124 I--HCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILEN- 180
Query: 130 YAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTW-WQIPPVAQVELKGELP 188
YA+P + + +DSH+ GG+G + + DA + A G W + P V V+L G L
Sbjct: 181 YAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMA-GIPWELKCPKVIGVKLTGSLS 239
Query: 189 AGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPV 248
S KD+I+ + G+ +E+ G +D I TI NM E GA + +FP
Sbjct: 240 GWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPY 299
Query: 249 DNVLLDFYRNRLTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYV 308
++ + + L+K G E N D L DP Y + + I+LS L ++
Sbjct: 300 NHRM----KKYLSKTG------REDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHI 349
Query: 309 SGPNSVKISSTVDDLSK------QDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQV 362
+GP + ++ V ++ K + + + SCTNS D+ +A V +
Sbjct: 350 NGPFTPDLAHPVAEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQA----LA 405
Query: 363 HKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGL-LEEGQV 421
H + +F I G Q L + G + L CGPCIG +++G+
Sbjct: 406 HGLKCKSQFTITPGSEQIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEK 465
Query: 422 G--ISATNRNFKGRM-GSKDALAYLASPSVVAASAILGKIGSPAE---VLGTKDPNFTGV 475
+++ NRNF GR + + A++ SP +V A AI G + E + GT F
Sbjct: 466 NTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLE 525
Query: 476 VATVEDAPATSAD-GKDV------------ADESGASGSVEILEGFPSEISGELV----- 517
++ P D G+D D S S +++LE F +L
Sbjct: 526 APDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQIL 585
Query: 518 -----LCDADNINTDGIYPGKYTYQDDVPKETM-AKVCMENYD---------------PD 556
C D+I+ G + + D++ + + +EN PD
Sbjct: 586 IKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPD 645
Query: 557 ---FQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNALL 613
+ K ++I N+G GSSRE AA G + +++ SF I N LL
Sbjct: 646 TARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLL 705
Query: 614 TL 615
L
Sbjct: 706 PL 707
>SPBP4H10.15 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 905
Score = 144 bits (362), Expect = 6e-34
Identities = 131/481 (27%), Positives = 216/481 (44%), Gaps = 50/481 (10%)
Query: 1 MFRVQRLRMFSTSRALYAGQNMTEKIVQRHAVGLPEGKTVVSGD------YVSIKPAHCM 54
M ++Q++R F + L + EK++ H V E + VS Y+ + P
Sbjct: 42 MGKLQQVRKFLPGQKL----TLAEKVLYSHLVNPEESFSGVSPSDIRGSLYLKLNPDRVA 97
Query: 55 SHDNSWPVAL-KFMGLGASTIKNPRQVVNTLDH----------DVQNKSEKNLTKYKNIE 103
D S +AL +FM G P + DH D+ + N + ++
Sbjct: 98 MQDASAQMALLQFMTCGLEKTMIPASI--HCDHLIVGHRGANSDIPDSIANNKEIFDFLQ 155
Query: 104 NFAKKHGIDFYPAGRGIGHQIMIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAA 163
+ AKK+GI F+ G GI HQI++E YA P M + +DSH+ GG+G + + D
Sbjct: 156 SAAKKYGIQFWGPGSGIIHQIVLEN-YAAPGGMMLGTDSHTPNAGGLGMIAIGVGGAD-- 212
Query: 164 AIWATGQTWWQI--PPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSL 221
A+ A T W++ P + V L G + + KD+I+ L G H IE+ G +
Sbjct: 213 AVDAMTNTPWELKAPKIIGVNLTGAMSGWTTPKDLILHLAGKLTVRGGTGHIIEYFGPGV 272
Query: 222 DKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQAK 281
+ T+ NM E GA + +FP + + R + + + +A +E+ ++
Sbjct: 273 ASLSCTGMATVCNMGAEVGATTSIFPYTDSM------RRYLIATHRAEVADA-ASEVHSE 325
Query: 282 SDSLQADPDAKYAKKLIIDLSTLTHYVSGPNSVKISSTVD------DLSKQDIKVNKAYL 335
+ L AD AKY + + I+LS LT ++GP + +S+ V + +K K++ +
Sbjct: 326 YNYLAADTGAKYDQIIDINLSELTPSLNGPFTPDLSTPVSKFGEAIEKNKWPKKLSAGLI 385
Query: 336 VSCTNSRLSDLESAANVVCPSGDINQVHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLN 395
SCTNS D+ +VV + K V F + G ++L
Sbjct: 386 GSCTNSSYQDMTCVVDVVEQAISAGLKPK----VPFLVTPGSEQIRATIERDGITERLEE 441
Query: 396 AGCLPLPAGCGPCIGL--GTGLLEEGQVG--ISATNRNFKGRM-GSKDALAYLASPSVVA 450
AG L CGPCIG+ T + G+ +++ NRNF+ R G+ + +L SP +VA
Sbjct: 442 AGATVLANACGPCIGMWKRTDDIASGEPNAILTSFNRNFRSRNDGNPSTMNFLTSPVIVA 501
Query: 451 A 451
A
Sbjct: 502 A 502
>CE25005 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 777
Score = 143 bits (360), Expect = 1e-33
Identities = 163/663 (24%), Positives = 275/663 (40%), Gaps = 92/663 (13%)
Query: 22 MTEKIVQRHAVGLPEGKTVVSG-DYVSIKPAHCMSHDNSWPVA-LKFMGLGASTIKNPRQ 79
++EKI+ H + P+ + + G Y+ ++P D + +A L+F+ G P
Sbjct: 62 LSEKILYGH-LDQPKTQDIERGVSYLRLRPDRVAMQDATAQMAMLQFISSGLPKTAVPST 120
Query: 80 VVNTLDH--DVQNKSEKNLTKYKNIE----NF----AKKHGIDFYPAGRGIGHQIMIEEG 129
+ DH + Q ++L + K++ NF K+G+ F+ G GI HQI++E
Sbjct: 121 I--HCDHLIEAQKGGAQDLARAKDLNKEVFNFLATAGSKYGVGFWKPGSGIIHQIILEN- 177
Query: 130 YAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPA 189
YAFP + + +DSH+ GG+G L + DA + A + P V ++L G+L
Sbjct: 178 YAFPGLLLIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKVIGIKLTGKLNG 237
Query: 190 GISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVD 249
S KD+I+ + + +E+ G +D I TI NM E GA + +FP +
Sbjct: 238 WTSAKDVILKVADILTVKGGTGAIVEYFGPGVDSISATGMGTICNMGAEIGATTSVFPYN 297
Query: 250 NVLLDFYRNRLTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVS 309
+ + I E E + D L AD A Y + + I+L TLT +V+
Sbjct: 298 ESMYKYLE------ATGRKEIAE----EARKYKDLLTADDGANYDQIIEINLDTLTPHVN 347
Query: 310 GPNSVKISSTVDDLSKQ--------DIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQ 361
GP + ++S++D L + D+KV + + SCTNS D+ AA++ + D
Sbjct: 348 GPFTPDLASSIDKLGENAKKNGWPLDVKV--SLIGSCTNSSYEDMTRAASIAKQALDKGL 405
Query: 362 VHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGL-LEEGQ 420
K F I G + + G + L CGPCIG +++G+
Sbjct: 406 KAKTI----FTITPGSEQVRATIERDGLSKIFADFGGMVLANACGPCIGQWDRQDVKKGE 461
Query: 421 VG--ISATNRNFKGRMGSKDAL-AYLASPSVVAASAILGKIG-SPA--EVLGTKDPNFTG 474
+++ NRNF GR + A ++ SP + A AI G++ +P E+ F
Sbjct: 462 KNTIVTSYNRNFTGRNDANPATHGFVTSPDITTAMAISGRLDFNPLTDELTAADGSKFKL 521
Query: 475 VVATVEDAPATSAD----------GKDVADESGASGSVEILEGFPS-------------E 511
T D P D G D S +S +++L F +
Sbjct: 522 QAPTGLDLPPKGYDPGEDTFQAPSGSGQVDVSPSSDRLQLLSPFDKWDGKDLEDMKILIK 581
Query: 512 ISGELVLCDADNINTDGIYPGKYTYQDDVPKET-MAKVCMENYDPDFQTKANPGD----- 565
++G+ C D+I+ G + + D++ + + +N + + G+
Sbjct: 582 VTGK---CTTDHISAAGPWLKYRGHLDNISNNLFLTAINADNGEMNKVKNQVTGEYGAVP 638
Query: 566 -------------ILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNAL 612
+ I N+G GSSRE AA G + ++ SF I N +
Sbjct: 639 ATARKYKADGVRWVAIGDENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGM 698
Query: 613 LTL 615
L L
Sbjct: 699 LPL 701
>YJL200c [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 789
Score = 142 bits (357), Expect = 2e-33
Identities = 159/669 (23%), Positives = 271/669 (39%), Gaps = 90/669 (13%)
Query: 22 MTEKIVQRHAVGLPEG------KTVVSGDYVSIKPAHCMSHDNSWPVAL-KFMGLGASTI 74
+ EKI+ H E T+ Y+ + P D S +AL +FM G +
Sbjct: 56 LAEKILYSHLCDPEESITSSDLSTIRGNKYLKLNPDRVAMQDASAQMALLQFMTTGLNQT 115
Query: 75 KNPRQVVNTLDH----------DVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQI 124
P + DH D+ + N + +E+ AK++GI F+ G GI HQI
Sbjct: 116 SVPASI--HCDHLIVGKDGETKDLPSSIATNQEVFDFLESCAKRYGIQFWGPGSGIIHQI 173
Query: 125 MIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTW-WQIPPVAQVEL 183
++E ++ P M + +DSH+ GG+GA+ + DA TG W + P + V+L
Sbjct: 174 VLEN-FSAPGLMMLGTDSHTPNAGGLGAIAIGVGGADAVDA-LTGTPWELKAPKILGVKL 231
Query: 184 KGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALS 243
G+L + KD+I L G+ + +E+ G+ + + TI NM E GA +
Sbjct: 232 TGKLNGWSTPKDVITKLAGLLTVRGGTGYIVEYFGEGVSTLSCTGMATICNMGAEIGATT 291
Query: 244 GLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLST 303
FP + + N + EA L K + L+AD DA+Y K + IDLS
Sbjct: 292 STFPYQEAHKRYLQ------ATNRAEVAEAADVALN-KFNFLRADKDAQYDKVIEIDLSA 344
Query: 304 LTHYVSGPNSVKISSTVDDLSKQDI------KVNKAYLVSCTNSRLSDLESAANVVCPSG 357
+ +V+GP + +S+ + +++ + KV+ + SCTNS D+ ++V +
Sbjct: 345 IEPHVNGPFTPDLSTPISQYAEKSLKENWPQKVSAGLIGSCTNSSYQDMSRVVDLVKQAS 404
Query: 358 DINQVHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLG----- 412
+ + F++ G G L CGPCIG
Sbjct: 405 KAG----LKPRIPFFVTPGSEQIRATLERDGIIDIFQENGAKVLANACGPCIGQWNREDV 460
Query: 413 TGLLEEGQVGISATNRNFKGRM-GSKDALAYLASPSVVAASAILGKIGSPAEVLGTKDPN 471
+ +E ++ NRNF+ R G+++ + +L SP +V A + G K PN
Sbjct: 461 SKTSKETNTIFTSFNRNFRARNDGNRNTMNFLTSPEIVTAMSYSGDAQFNPLTDSIKLPN 520
Query: 472 ---FTGVVATVEDAPATSAD--------GKDVADESGA-------SGSVEILEGFP---- 509
F ++ P + D +S S +++LE F
Sbjct: 521 GKDFKFQPPKGDELPKRGFEHGRDKFYPEMDPKPDSNVEIKVDPNSDRLQLLEPFKPWNG 580
Query: 510 SEISGELVL-----CDADNINTDGIYPGKYTYQDDVPKETMAKV-------CMENYDPDF 557
E+ ++L C D+I+ G++ + +++ T+ + YD D
Sbjct: 581 KELKTNVLLKVEGKCTTDHISAAGVWLKYKGHLENISYNTLIGAQNKETGEVNKAYDLDG 640
Query: 558 QTKANPGDIL-----------ISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRN 606
PG ++ I+ N+G GS+RE AA + G ++++ SF I N
Sbjct: 641 TEYDIPGLMMKWKSDGRPWTVIAEHNYGEGSAREHAALSPRFLGGEILLVKSFARIHETN 700
Query: 607 SINNALLTL 615
+L L
Sbjct: 701 LKKQGVLPL 709
>SPAC24C9.06c [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 778
Score = 134 bits (338), Expect = 4e-31
Identities = 163/663 (24%), Positives = 275/663 (40%), Gaps = 92/663 (13%)
Query: 23 TEKIVQRHAVGLPEGKTVVSG-DYVSIKPAHCMSHDNSWPVA-LKFMGLGASTIKNPRQV 80
+EKI+ H + P + + G Y+ ++P D + +A L+FM G + P V
Sbjct: 62 SEKILYGH-LDDPVNQDIERGVSYLKLRPDRVACQDATAQMAILQFMSAGMPEVAVP--V 118
Query: 81 VNTLDH----------DVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQIMIEEGY 130
DH D++ + N Y ++ K+ I F+ G GI HQI++E Y
Sbjct: 119 TVHCDHLIEAYEGGPIDLERANVTNKEVYDFLQTACAKYNIGFWRPGSGIIHQIVLEN-Y 177
Query: 131 AFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPAG 190
AFP + + +DSH+ GG+G + + DA + A + P V V+L G+L
Sbjct: 178 AFPGGLLIGTDSHTPNAGGLGMVAIGVGGADAVDVMANLPWELKCPKVIGVKLTGQLKGW 237
Query: 191 ISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVDN 250
S KD+I+ + G+ +E+ G ++ + TI NM E GA + +FP +
Sbjct: 238 TSPKDVILKVAGILTVKGGTGAIVEYFGPGVESLSCTGMGTICNMGAEIGATTSIFPFNP 297
Query: 251 VLLDFYRNRLTKVGNNHPRINEARINELQAK-SDSLQADPDAKYAKKLIIDLSTLTHYVS 309
+ ++ R N + I + + + + AD +A Y + + IDL+TL +++
Sbjct: 298 RMSEYLR-----------ATNRSAIADYAEEFAPIIAADENAHYDQIIEIDLNTLEPHLN 346
Query: 310 GPNSVKISSTVDDLSK--------QDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQ 361
GP + +++ + + Q++KV + SCTNS D+ AA++ + D
Sbjct: 347 GPFTPDLATPISKFKEAVKKNDWPQELKV--GLIGSCTNSSYEDMSRAASICQQAIDKGI 404
Query: 362 VHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGL-LEEGQ 420
K F I G + AG + L CGPCIG +++G+
Sbjct: 405 KTKSL----FTITPGSEQVRATLTRDGQLDTMRKAGGIVLANACGPCIGQWKRTDVKKGE 460
Query: 421 VG--ISATNRNFKGRMGSKDAL-AYLASPSVVAASAILGKIG-SP-AEVLGTKD------ 469
+++ NRNF GR + A A++ SP +V A G + +P + L KD
Sbjct: 461 KNSIVTSYNRNFTGRNDANPATHAFVTSPDIVTAMVFSGDMNFNPLTDTLKDKDGNDFKF 520
Query: 470 --PNFTGVVATVED------APATSADGKDVADESGASGSVEILEGFP----SEISGELV 517
P G+ + D +S + KDVA + S ++ L F ++ G +
Sbjct: 521 EPPTGAGLPSKGYDPGSNTYVAPSSVNVKDVAIDP-HSKRLQRLTPFKKWDGKDMKGLKI 579
Query: 518 L------CDADNINTDGIYPGKYTYQDDVPKETM----------AKVCMENYDPDFQTKA 561
L C D+I+ G + + ++ M A + +++T
Sbjct: 580 LIKAKGKCTTDHISAAGPWLKYRGHLQNISNNYMIGAINAENGEANKLKDQLTGEYKTVP 639
Query: 562 NPGD---------ILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNAL 612
N + + NFG GSSRE AA G V++ SF I N L
Sbjct: 640 NVAIDYRDHGIRWVTLGEQNFGEGSSREHAALEPRYLGGAAVITKSFARIHETNLKKQGL 699
Query: 613 LTL 615
L L
Sbjct: 700 LPL 702
>7298762 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 683
Score = 132 bits (332), Expect = 2e-30
Identities = 147/586 (25%), Positives = 240/586 (40%), Gaps = 73/586 (12%)
Query: 87 DVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQIMIEEGYAFPLTMTVASDSHSNT 146
D+ + N Y + + K+G+ F+ G GI HQI++E YAFP + + +DSH+
Sbjct: 42 DLARAKDLNKEVYDFLASTCAKYGLGFWKPGSGIIHQIILEN-YAFPGLLMIGTDSHTPN 100
Query: 147 YGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQ 206
GG+G L + DA + A + P V V L G++ S KD+I+ + +
Sbjct: 101 GGGLGGLCIGVGGADAVDVMADIPWELKCPKVIGVNLTGKISGWTSPKDVILKVADILTV 160
Query: 207 DQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNN 266
IE+ G +D I TI NM E GA + LFP + + D+ ++
Sbjct: 161 KGGTGAIIEYHGKGVDSISCTGMATICNMGAEIGATTSLFPFNQRMADYLKST-----GR 215
Query: 267 HPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVSGPNSVKISSTVDDLSKQ 326
+EA+ + QAK L AD + +Y + + I+L TL +V+GP + + + L +
Sbjct: 216 AGIASEAQ--KYQAK--ILSADKNCEYDELIEINLDTLEPHVNGPFTPDLGHPISKLGEN 271
Query: 327 DIK------VNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVAEGVEFYIXXXXXXX 380
K + + SCTNS D+ A++ + H + + F +
Sbjct: 272 SKKNGYPMDIRVGLIGSCTNSSYEDMGRCASIAKDA----MSHGLKSKIPFNVTPGSEQI 327
Query: 381 XXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGL-LEEGQVG--ISATNRNFKGRMGSK 437
G + G L CGPCIG +++G +++ NRNF GR +
Sbjct: 328 RATIERDGISEVFDKFGGTVLANACGPCIGQWDRKDVKKGDKNTIVTSYNRNFTGRNDAN 387
Query: 438 DAL-AYLASPSVVAASAILGKIG-SPA--EVLGTKDPNFTGVVATVEDAPATSAD-GKDV 492
A ++ SP +V A +I G++ +P E+ G F ++ PA D G+D
Sbjct: 388 PATHCFVTSPELVTALSIAGRLDFNPLTDELTGADGKKFKLKAPFGDELPAKGFDPGQDT 447
Query: 493 ADESGASGS------------VEILEGFP----SEISGELVL------CDADNINTDGIY 530
SG +++LE F +++ VL C D+I+ G +
Sbjct: 448 YTAPPPSGENVKVAVDPKSTRLQLLEPFDKWNGQDLTDLTVLIKVKGKCTTDHISAAGPW 507
Query: 531 PGKYTYQDDVPKETMAKVCMENYD------------------PDF--QTKANPGD-ILIS 569
+ D++ + NY+ PD KAN + +
Sbjct: 508 LKYRGHLDNISNNMF--IGATNYENNEMNNIKNQRNGSWGGVPDVARDYKANGIKWVAVG 565
Query: 570 GFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNALLTL 615
N+G GSSRE AA G + ++ SF I N LL L
Sbjct: 566 DENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGLLPL 611
>7299398 [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
Length = 769
Score = 130 bits (328), Expect = 5e-30
Identities = 155/666 (23%), Positives = 262/666 (39%), Gaps = 95/666 (14%)
Query: 22 MTEKIVQRHAVGLPEGKTVVSG-DYVSIKPAHCMSHDNSWPVAL-KFMGLGASTIKNPRQ 79
++EK++ H + P+ + + G Y+ ++P D + + L +F+ G + P
Sbjct: 49 LSEKVLYSH-LDQPDSQEIERGKSYLRLRPDRVALQDATAQMTLLQFISSGLKKVAVPST 107
Query: 80 VVNTLDH--DVQNKSEKNLTKYKNIE--------NFAKKHGIDFYPAGRGIGHQIMIEEG 129
V DH + Q +K+L + K++ + K+ + F+ G GI HQI++E
Sbjct: 108 V--HCDHLIEAQISGDKDLARAKDLNKEVYDFLSSACAKYNLGFWKPGSGIIHQIILEN- 164
Query: 130 YAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPA 189
YAFP + + +DSH+ GG+G L + DA + A + P V L G++
Sbjct: 165 YAFPGLLMIGTDSHTPNGGGLGCLCVGVGGADAVDVMANIPWELKCPTVIGCHLTGKISG 224
Query: 190 GISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVD 249
S KD+I+ + + +E+ G ++ I TI NM E GA + +FP +
Sbjct: 225 WTSPKDVILKVAEILTVKGGTGAIVEYHGPGVESISCTGMATITNMGAEIGATTSIFPFN 284
Query: 250 NVLLDFYRNRLTKVGNNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVS 309
++ + R T G A +E D L D KY K + I+L TL V+
Sbjct: 285 ERMVTYL--RATGRG--------AIADEATKNKDLLVPDEGCKYDKVIEINLDTLEPLVN 334
Query: 310 GPNSVKISSTVDDLSKQD------IKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVH 363
GP + ++ + L + +++ + + SCTNS D+ A++ + H
Sbjct: 335 GPFTPDLAHPISKLGQNSEKNGYPMEIKVSLIGSCTNSSYEDMGRCASIANDA----LGH 390
Query: 364 KVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTG---LLEEGQ 420
+ V F + G L G L CGPCIG + E
Sbjct: 391 GLKSCVPFNVTPGSEQVRATIARDGIIDVLEKFGGTVLANACGPCIGQWDRKDVKMGEKN 450
Query: 421 VGISATNRNFKGRMGSKDAL-AYLASPSVVAASAILGKI----------GSPAEVLGTKD 469
+++ NRNF GR + A ++ SP + A AI G++ G+ + K+
Sbjct: 451 TIVTSYNRNFTGRNDANPATHCFVTSPEMATALAIAGRLDFNPMTDELTGTDGKTFKLKE 510
Query: 470 PN--------FTGVVATVEDAPATSADGKDVADESGASGSVEILEGFPS----------- 510
P+ F T + PA + D K D S +++LE F
Sbjct: 511 PHGEELPSKGFDPGEDTYQAPPAKADDIKVNVDPK--SDRLQLLEPFEKWDGKDYIDLMV 568
Query: 511 --EISGELVLCDADNINTDGIYPGKYTYQDDVPKET-MAKVCMENYDPDFQTKANPGDI- 566
+I G+ C D+I+ G + + D++ + EN + + G
Sbjct: 569 LIKIKGK---CTTDHISAAGPWLKYRGHLDNISNNMFIGATNAENNEMNKVKNQKTGSFD 625
Query: 567 -----------------LISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSIN 609
+ N+G GSSRE AA G ++ SF I N
Sbjct: 626 AVPAVARDYKANKIKWCAVGEENYGEGSSREHAALEPRHLGGVAIIVKSFARIHETNLKK 685
Query: 610 NALLTL 615
+L L
Sbjct: 686 QGMLAL 691
>7300911 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 902
Score = 106 bits (264), Expect = 1e-22
Identities = 129/534 (24%), Positives = 205/534 (38%), Gaps = 95/534 (17%)
Query: 21 NMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHD-NSWPVALKFMGLGASTIK---N 76
++ EK VQ P K S VS KPA + D P + F + + + N
Sbjct: 57 HVLEKDVQSILGWTPSLKQETSDVEVSFKPARVILQDFTGVPAVVDFAAMRDAVRELGGN 116
Query: 77 PRQVVN------TLDHDVQN---KSEKNLTKYKNIENFAKKHGIDFY------------- 114
P ++ +DH VQ +S LTK +++E K F
Sbjct: 117 PEKINPICPADLVIDHSVQVDFVRSSDALTKNESLEFQRNKERFTFLKWGARAFDNMLIV 176
Query: 115 PAGRGIGHQIMIE---------------EGYAFPLTMTVASDSHSNTYGGIGALGTPIVR 159
P G GI HQ+ +E +P ++ V +DSH+ G+G LG +
Sbjct: 177 PPGSGIVHQVNLEYLARVVFESDSSADGSKILYPDSV-VGTDSHTTMINGLGVLGWGVGG 235
Query: 160 TDAAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGD 219
+A A+ +P V L+G+L + D+++ + Q V+ +EF G
Sbjct: 236 IEAEAVMLGQSISMLLPEVIGYRLEGKLGPLATSTDLVLTITKHLRQLGVVGKFVEFYGP 295
Query: 220 SLDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQ 279
+ ++ I R TI+NM E+GA G FP+D L + R T I + +
Sbjct: 296 GVAELSIADRATISNMCPEYGATVGYFPIDENTLSYMRQ--TNRSEKKIDIIRKYLKATR 353
Query: 280 AKSDSLQADPDAKYAKKLIIDLSTLTHYVSGP----NSVKISSTVDDLSK---------- 325
D D D +Y + + +DLST+ VSGP + V +SS +D
Sbjct: 354 QLRDYSLVDQDPQYTESVTLDLSTVVTSVSGPKRPHDRVSVSSMCEDFKSCLISPVGFKG 413
Query: 326 ----------------QDIKVNK--------AYLVSCTNSRLSDLESAANVVCPSGDINQ 361
D K K A + SCTN+ + A ++ + + +
Sbjct: 414 FAIPPSALAASGEFQWDDGKSYKIGHGSVVIAAITSCTNTSNPSVMLGAGLLAKNA-VQK 472
Query: 362 VHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQV 421
+ ++ + +G L G + GC CIG +G L+E V
Sbjct: 473 GLSILPYIKTSLSPGSGVVTYYLRESGVIPYLEQLGFDIVGYGCMTCIG-NSGPLDENVV 531
Query: 422 -----------GISATNRNFKGRMGSKDALAYLASPSVVAASAILGKIGSPAEV 464
G+ + NRNF+GR+ YLASP +V A AI G++ E+
Sbjct: 532 NTIEKNGLVCCGVLSGNRNFEGRIHPNTRANYLASPLLVIAYAIAGRVDIDFEI 585
>At4g26970 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 907
Score = 103 bits (257), Expect = 9e-22
Identities = 123/483 (25%), Positives = 194/483 (39%), Gaps = 84/483 (17%)
Query: 63 ALKFMGLGASTIKNPRQVVNTLDHDVQ-------NKSEKNLTKY--KNIENFA-KKHGID 112
A+K +G S I V +DH +Q + ++KNL +N E F K G
Sbjct: 116 AVKNLGSDPSKINPLVPVDLVVDHSIQVDFARSEDAAQKNLELEFKRNKERFTFLKWGST 175
Query: 113 FY------PAGRGIGHQIMIE---------EGYAFPLTMTVASDSHSNTYGGIGALGTPI 157
+ P G GI HQ+ +E +G+ +P ++ V +DSH+ G+G G +
Sbjct: 176 AFQNMLVVPPGSGIVHQVNLEYLGRVVFNSKGFLYPDSV-VGTDSHTTMIDGLGVAGWGV 234
Query: 158 VRTDAAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFT 217
+A A +P V +L G+L G++ D+++ + + + V+ +EF
Sbjct: 235 GGIEAEAAMLGQPMSMVLPGVVGFKLDGKLKEGVTATDLVLTVTQILRKHGVVGKFVEFY 294
Query: 218 GDSLDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARIN- 276
G+ + ++ + R TIANM+ E+GA G FPVD+V L++ L G + +N ++
Sbjct: 295 GEGMSELSLADRATIANMSPEYGATMGFFPVDHVTLEY----LKLTGRSDETVNPLSLSL 350
Query: 277 ELQAKSDS-LQADPDAKYAKKLIIDLSTLTHYVSGP---------------------NSV 314
L S + Y L ++L + +SGP N V
Sbjct: 351 SLSLLFYSFFFGKQERAYTSYLQLELGHVEPCISGPKRPHDRVPLKDMKADWHACLDNPV 410
Query: 315 KISSTVDDLSKQDIKVNKAY----------------LVSCTN-SRLSDLESAANVVCPSG 357
KQ+ V +Y + SCTN S S + AA V +
Sbjct: 411 GFKGFAVPKEKQEEVVKFSYNGQPAEIKHGSVVIAAITSCTNTSNPSVMIGAALVAKKAS 470
Query: 358 DINQVHKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLE 417
D+ KV V+ + +G + L G + GC CIG L
Sbjct: 471 DLGL--KVKPWVKTSLAPGSRVVEKYLDRSGLRESLTKQGFEIVGYGCTTCIGNSGNLDP 528
Query: 418 EGQVGISAT----------NRNFKGRMGSKDALAYLASPSVVAASAILG--KIGSPAEVL 465
E I T NRNF+GR+ + YLASP +V A A+ G I E +
Sbjct: 529 EVASAIEGTDIIPAAVLSGNRNFEGRVHPQTRANYLASPPLVVAYALAGTVDIDFEKEPI 588
Query: 466 GTK 468
GT+
Sbjct: 589 GTR 591
>Hs8659555 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 889
Score = 100 bits (248), Expect = 1e-20
Identities = 112/451 (24%), Positives = 179/451 (38%), Gaps = 84/451 (18%)
Query: 84 LDHDVQ---NKSEKNLTKYKNIE--------NFAKK-----HGIDFYPAGRGIGHQIMIE 127
+DH +Q N+ +L K +++E F K H + P G GI HQ+ +E
Sbjct: 124 IDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLE 183
Query: 128 ---------EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPV 178
+GY +P ++ V +DSH+ G+G LG + +A A+ +P V
Sbjct: 184 YLARVVFDQDGYYYPDSL-VGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQV 242
Query: 179 AQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTE 238
L G+ ++ DI++ + Q V+ +EF G + ++ I R TIANM E
Sbjct: 243 IGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPE 302
Query: 239 WGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQAKS---DSLQADPDAKYAK 295
+GA + FPVD V + + L + G + ++ + LQA D D + +
Sbjct: 303 YGATAAFFPVDEVSITY----LVQTGRDEEKLKYIK-KYLQAVGMFRDFNDPSQDPDFTQ 357
Query: 296 KLIIDLSTLTHYVSGPNSVKISSTVDDL---------SKQDIK----------------- 329
+ +DL T+ SGP + V D+ +KQ K
Sbjct: 358 VVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIY 417
Query: 330 -----------VNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVAEGVEFYIXXXXX 378
V A + SCTN+ + A ++ ++ V ++ +
Sbjct: 418 DNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKA-VDAGLNVMPYIKTSLSPGSG 476
Query: 379 XXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEG-----------QVGISATN 427
+G L G + GC CIG +G L E VG+ + N
Sbjct: 477 VVTYYLQESGVMPYLSQLGFDVVGYGCMTCIG-NSGPLPEPVVEAITQGDLVAVGVLSGN 535
Query: 428 RNFKGRMGSKDALAYLASPSVVAASAILGKI 458
RNF+GR+ YLASP +V A AI G I
Sbjct: 536 RNFEGRVHPNTRANYLASPPLVIAYAIAGTI 566
>7299336 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 899
Score = 99.4 bits (246), Expect = 2e-20
Identities = 127/527 (24%), Positives = 202/527 (38%), Gaps = 94/527 (17%)
Query: 21 NMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHD-NSWPVALKF-------MGLGAS 72
++ EK VQ P K + VS KPA + D P + F + LG
Sbjct: 55 HILEKDVQSILGWSPALKQGSNDVEVSFKPARVILQDFTGVPAVVDFAAMRDAVLDLGGD 114
Query: 73 TIK-NPRQVVN-TLDHDVQ---NKSEKNLTKYKNIENFAKKHGIDFY------------- 114
K NP + +DH VQ ++ L K +++E K F
Sbjct: 115 PEKINPICPADLVIDHSVQVDFARAPDALAKNQSLEFERNKERFTFLKWGAKAFNNMLIV 174
Query: 115 PAGRGIGHQIMIE--------------EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRT 160
P G GI HQ+ +E +P ++ V +DSH+ G+G LG +
Sbjct: 175 PPGSGIVHQVNLEYLARVVFENDATDGSKILYPDSV-VGTDSHTTMINGLGVLGWGVGGI 233
Query: 161 DAAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDS 220
+A A+ +P V +L+G+L ++ D+++ + Q V+ +EF G
Sbjct: 234 EAEAVMLGQSISMLLPEVIGYKLEGKLSPLVTSTDLVLTITKHLRQLGVVGKFVEFYGPG 293
Query: 221 LDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQA 280
+ ++ I R TI+NM E+GA G FP+D L + + T I + Q
Sbjct: 294 VAELSIADRATISNMCPEYGATVGYFPIDENTLGYMKQ--TNRSEKKIDIIRQYLKATQQ 351
Query: 281 KSDSLQADPDAKYAKKLIIDLSTLTHYVSGP----NSVKISSTVDDLSK----------- 325
+ A D K+ + + +DLST+ VSGP + V +S +D
Sbjct: 352 LRNYADAAQDPKFTQSITLDLSTVVTSVSGPKRPHDRVSVSDMPEDFKSCLSSPVGFKGF 411
Query: 326 ---------------QDIKVNK--------AYLVSCTNSRLSDLESAANVVCPSGDINQV 362
D K K A + SCTN+ + A ++ + +
Sbjct: 412 AIAPEAQSAFGEFQWDDGKTYKLHHGSVVIAAITSCTNTSNPSVMLGAGLLAKKA-VEKG 470
Query: 363 HKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQV- 421
+ ++ + +G L G + GC CIG +G LEE V
Sbjct: 471 LSILPYIKTSLSPGSGVVTYYLKESGVIPYLEKLGFDIVGYGCMTCIG-NSGPLEENVVN 529
Query: 422 ----------GISATNRNFKGRMGSKDALAYLASPSVVAASAILGKI 458
G+ + NRNF+GR+ YLASP +V A AI G++
Sbjct: 530 TIEKNGLVCAGVLSGNRNFEGRIHPNTRANYLASPLLVIAYAIAGRV 576
>At4g35830 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 898
Score = 98.6 bits (244), Expect = 3e-20
Identities = 114/465 (24%), Positives = 188/465 (39%), Gaps = 83/465 (17%)
Query: 70 GASTIKNPRQVVN-TLDHDVQ-------NKSEKN--LTKYKNIENFA-------KKHGID 112
G S NP V+ +DH VQ N + N L +N E FA H +
Sbjct: 113 GDSNKINPLVPVDLVIDHSVQVDVARSENAVQANMELEFQRNKERFAFLKWGSNAFHNML 172
Query: 113 FYPAGRGIGHQIMIE---------EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAA 163
P G GI HQ+ +E G +P ++ V +DSH+ G+G G + +A
Sbjct: 173 VVPPGSGIVHQVNLEYLARVVFNTNGLLYPDSV-VGTDSHTTMIDGLGVAGWGVGGIEAE 231
Query: 164 AIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDK 223
A +P V +L G+L G++ D+++ + + + V+ +EF G+ + +
Sbjct: 232 ATMLGQPMSMVLPGVVGFKLTGKLRDGMTATDLVLTVTQMLRKHGVVGKFVEFHGEGMRE 291
Query: 224 IPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQAKSD 283
+ + R TIANM+ E+GA G FPVD+V L + RLT ++ + EA + + D
Sbjct: 292 LSLADRATIANMSPEYGATMGFFPVDHVTLQYL--RLTGRSDDTVSMIEAYLRANKMFVD 349
Query: 284 SLQADPDAKYAKKLIIDLSTLTHYVSGPN------------------------------- 312
+ + Y+ L ++L + VSGP
Sbjct: 350 YSEPESKTVYSSCLELNLEDVEPCVSGPKRPHDRVPLKEMKADWHSCLDNRVGFKGFAVP 409
Query: 313 --------SVKISSTVDDLSKQDIKVNKAYLVSCTN-SRLSDLESAANVVCPSGDINQVH 363
+ T L D+ + A + SCTN S S + AA V + D+
Sbjct: 410 KEAQSKAVEFNFNGTTAQLRHGDVVI--AAITSCTNTSNPSVMLGAALVAKKACDLGL-- 465
Query: 364 KVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIG--------LGTGL 415
+V ++ + +G + L G + GC CIG + + +
Sbjct: 466 EVKPWIKTSLAPGSGVVTKYLAKSGLQKYLNQLGFSIVGYGCTTCIGNSGDIHEAVASAI 525
Query: 416 LEEGQV--GISATNRNFKGRMGSKDALAYLASPSVVAASAILGKI 458
++ V + + NRNF+GR+ YLASP +V A A+ G +
Sbjct: 526 VDNDLVASAVLSGNRNFEGRVHPLTRANYLASPPLVVAYALAGTV 570
>CE03812 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 887
Score = 97.4 bits (241), Expect = 6e-20
Identities = 121/476 (25%), Positives = 186/476 (38%), Gaps = 91/476 (19%)
Query: 63 ALKFMGLGASTIKNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDF--------- 113
A++ MG + I V +DH VQ + Y N+E AK I+F
Sbjct: 101 AVQNMGADPAKINPVCPVDLVIDHSVQ------VDHYGNLEALAKNQSIEFERNRERFNF 154
Query: 114 -------------YPAGRGIGHQIMIE----------EGYAFPLTMTVASDSHSNTYGGI 150
P G GI HQ+ +E +G +P ++ V +DSH+ G
Sbjct: 155 LKWGSKAFDNLLIVPPGSGIVHQVNLEYLARTVFVGKDGVLYPDSV-VGTDSHTTMIDGS 213
Query: 151 GALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVL 210
G LG + +A A+ IP V EL G L ++ D+++ + V+
Sbjct: 214 GVLGWGVGGIEAEAVMLGQPISMVIPEVIGYELVGTLSDTVTSTDLVLTITKNLRDLGVV 273
Query: 211 NHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVG--NNHP 268
+EF G + + I R TIANM E+GA G FPVD+ +D+ LT+ G ++
Sbjct: 274 GKFVEFFGTGVASLSIADRATIANMCPEYGATIGFFPVDSRTIDY----LTQTGRDTDYT 329
Query: 269 RINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVSGP----NSVKISSTVDDLS 324
+ E + + + Y L +DL ++ VSGP + V+++S D S
Sbjct: 330 QRVEQYLKSVGMFVNFTDDSYRPTYTTTLKLDLGSVVPSVSGPKRPHDRVELASLAQDFS 389
Query: 325 K--QDIKVNKAY---------LVSCTNSR-----------LSDLESAANVVCPSGDINQV 362
K D KA+ V+ TN ++ + S N PS +
Sbjct: 390 KGLTDKISFKAFGLKPEDATKSVTITNHGRTAELTHGSVVIAAITSCTNTSNPSVMLAAG 449
Query: 363 HKVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNA-GCLP---------LPAGCGPCIGLG 412
+ VE + +G K L A G LP GC CIG
Sbjct: 450 LVAKKAVELGLNVQPYVKTSLSPGSGVVTKYLEASGLLPYLEKIGFNIAGYGCMTCIGNS 509
Query: 413 -------TGLLEEGQV---GISATNRNFKGRMGSKDALAYLASPSVVAASAILGKI 458
T +EE + G+ + NRNF+GR+ YLASP + +I+G +
Sbjct: 510 GPLDEPVTKAIEENNLVVAGVLSGNRNFEGRIHPHVRANYLASPPLAVLYSIIGNV 565
>At2g05710 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 898
Score = 95.9 bits (237), Expect = 2e-19
Identities = 113/465 (24%), Positives = 190/465 (40%), Gaps = 80/465 (17%)
Query: 69 LGASTIK-NPRQVVN-TLDHDVQ-------NKSEKN--LTKYKNIENFA-KKHGIDFY-- 114
LG+ + K NP V+ +DH VQ N + N L +N E FA K G +
Sbjct: 111 LGSDSNKINPLVPVDLVIDHSVQVDVARSENAVQANMELEFQRNKERFAFLKWGSTAFQN 170
Query: 115 ----PAGRGIGHQIMIE---------EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTD 161
P G GI HQ+ +E +G +P ++ V +DSH+ G+G G + +
Sbjct: 171 MLVVPPGSGIVHQVNLEYLGRVVFNTKGLLYPDSV-VGTDSHTTMIDGLGVAGWGVGGIE 229
Query: 162 AAAIWATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSL 221
A A +P V +L G++ G++ D+++ + + + V+ +EF G+ +
Sbjct: 230 AEATMLGQPMSMVLPGVVGFKLAGKMRNGVTATDLVLTVTQMLRKHGVVGKFVEFYGNGM 289
Query: 222 DKIPIDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRINEARINELQAK 281
+ + R TIANM+ E+GA G FPVD+V L + +LT + + EA +
Sbjct: 290 SGLSLADRATIANMSPEYGATMGFFPVDHVTLQYL--KLTGRSDETVAMIEAYLRANNMF 347
Query: 282 SDSLQADPDAKYAKKLIIDLSTLTHYVSGPNSVKISSTVDDL------------------ 323
D + D Y+ L ++L + +SGP T+ ++
Sbjct: 348 VDYNEPQQDRVYSSYLELNLDDVEPCISGPKRPHDRVTLKEMKADWHSCLDSKVGFKGFA 407
Query: 324 ---SKQDIKVNKAY----------------LVSCTNSRLSDLESAANVVCPSG-DINQVH 363
Q+ VN ++ + SCTN+ + A +V D+
Sbjct: 408 IPKEAQEKVVNFSFDGQPAELKHGSVVIAAITSCTNTSNPSVMLGAGLVAKKACDLGL-- 465
Query: 364 KVAEGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIG--------LGTGL 415
+V ++ + +G + L G + GC CIG +G +
Sbjct: 466 QVKPWIKTSLAPGSGVVTKYLLKSGLQEYLNEQGFNIVGYGCTTCIGNSGEINESVGAAI 525
Query: 416 LEEGQV--GISATNRNFKGRMGSKDALAYLASPSVVAASAILGKI 458
E V + + NRNF+GR+ YLASP +V A A+ G +
Sbjct: 526 TENDIVAAAVLSGNRNFEGRVHPLTRANYLASPPLVVAYALAGTV 570
>Hs17478037 [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase
superfamily)
Length = 963
Score = 92.8 bits (229), Expect = 2e-18
Identities = 102/416 (24%), Positives = 168/416 (39%), Gaps = 67/416 (16%)
Query: 115 PAGRGIGHQIMIE---------EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAI 165
P G G+ HQI +E + FP ++ V +DSH G+G LG + + A+
Sbjct: 246 PPGTGMAHQINLEYLSRVVFEEKDLLFPDSV-VGTDSHITMVNGLGILGWGVGGIETEAV 304
Query: 166 WATGQTWWQIPPVAQVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIP 225
+P V EL G ++ D+++ + Q V +EF G + ++
Sbjct: 305 MLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLS 364
Query: 226 IDYRLTIANMTTEWGALSGLFPVDNVLLDFYRNRLTKVGNNHPRIN--EARINELQAKSD 283
I R TIANM E+GA+ FPVDNV L L G + ++ E + ++ +
Sbjct: 365 IVDRTTIANMCPEYGAILSFFPVDNVTL----KHLEHTGFSKAKLESMETYLKAVKLFRN 420
Query: 284 SLQADPDAKYAKKLIIDLSTLTHYVSGPNSVKISSTVDDL-------------------- 323
+ + +Y++ + I+L+++ VSGP + V D+
Sbjct: 421 DQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIA 480
Query: 324 --SKQDI---------------KVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVA 366
++DI V A ++SCTN+ + AA ++ + +V
Sbjct: 481 AEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKA-VEAGLRVK 539
Query: 367 EGVEFYIXXXXXXXXXXXXXTGAWQKLLNAGCLPLPAGCGPCIGLGTGL-------LEEG 419
+ + +G L G + GC C+G L +++G
Sbjct: 540 PYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSICVGNTAPLSDAVLNAVKQG 599
Query: 420 QV---GISATNRNFKGRMGSKDALAYLASPSVVAASAILG--KIGSPAEVLGTKDP 470
+ GI + N+NF+GR+ YLASP +V A AI G I E LGT DP
Sbjct: 600 DLVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGT-DP 654
>At3g58990 [E] KOG0454 3-isopropylmalate dehydratase (aconitase superfamily)
Length = 253
Score = 54.3 bits (129), Expect = 6e-07
Identities = 40/121 (33%), Positives = 57/121 (47%), Gaps = 10/121 (8%)
Query: 498 ASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKY-TYQDDVP--KETMAKVCMENYD 554
A+ S + E E L DNI+TD I P +Y T +P +E + +
Sbjct: 58 AASSSDSGESITRETFHGLCFVLKDNIDTDQIIPAEYGTLIPSIPEDREKLGSFALNGLP 117
Query: 555 PDFQTK-ANPGD------ILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNS 607
+ + PG+ ++I G NFG GSSRE A + A G K VV+ S+ IFFRN
Sbjct: 118 KFYNERFVVPGEMKSKYSVIIGGDNFGCGSSREHAPVCLGAAGAKAVVAESYARIFFRNC 177
Query: 608 I 608
+
Sbjct: 178 V 178
>At2g43090 [E] KOG0454 3-isopropylmalate dehydratase (aconitase superfamily)
Length = 251
Score = 54.3 bits (129), Expect = 6e-07
Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 522 DNINTDGIYPGKY-TYQDDVPKE--TMAKVCMENYDPDFQTK-ANPGD------ILISGF 571
DNI+TD I P ++ T P+E + + ++ + PG+ I+I G
Sbjct: 79 DNIDTDQIIPAEFLTLVPSNPEEYEKLGSYALVGLPASYKERFVQPGEMKTKYSIIIGGE 138
Query: 572 NFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSI 608
NFG GSSRE A + A G K VV+ S+ IFFRNS+
Sbjct: 139 NFGCGSSREHAPVCLGAAGAKAVVAQSYARIFFRNSV 175
>At2g43100 [E] KOG0454 3-isopropylmalate dehydratase (aconitase superfamily)
Length = 256
Score = 53.5 bits (127), Expect = 1e-06
Identities = 36/103 (34%), Positives = 51/103 (48%), Gaps = 22/103 (21%)
Query: 522 DNINTDGI--------YPGKYTYQDDVPKETMAKVCMENYDPDFQTKA--NPGD------ 565
DNI+TD I +P +D++ ++ + PDF PG+
Sbjct: 85 DNIDTDQIIPAGAACTFPSNQQERDEIAAHALSGL------PDFHKTRFIEPGENRSKYS 138
Query: 566 ILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSI 608
I+I G NFG GSSRE A + A G K +V+ S+ IFFRNS+
Sbjct: 139 IIIGGENFGCGSSREHAPVCLGAAGAKAIVAESYARIFFRNSV 181
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,765,256
Number of Sequences: 60738
Number of extensions: 1799226
Number of successful extensions: 4327
Number of sequences better than 1.0e-05: 24
Number of HSP's better than 0.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 4232
Number of HSP's gapped (non-prelim): 50
length of query: 693
length of database: 30,389,216
effective HSP length: 113
effective length of query: 580
effective length of database: 23,525,822
effective search space: 13644976760
effective search space used: 13644976760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)