ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3763 good A KOG2412 RNA processing and modification Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3763 1327485 1325854 -544
(544 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL207w [A] KOG2412 Nuclear-export-signal (NES)-containing prote... 328 1e-89
SPBC31E1.05 [A] KOG2412 Nuclear-export-signal (NES)-containing p... 132 1e-30
Hs4557627 [A] KOG2412 Nuclear-export-signal (NES)-containing pro... 57 5e-08
>YDL207w [A] KOG2412 Nuclear-export-signal (NES)-containing
protein/polyadenylated-RNA export factor
Length = 538
Score = 328 bits (842), Expect = 1e-89
Identities = 184/421 (43%), Positives = 248/421 (58%), Gaps = 16/421 (3%)
Query: 136 TFPMQDQVLESVWNEEIDSIEKVNQRLIKSIKDKKKREEEARIQKECEAEKRRQXXXXXX 195
T P+ + + ES + ++ ++ NQ+ I+SI++ K+R EE R +KE E E++R+
Sbjct: 120 TAPLLEAIEES-FQRKMQNLVLANQKEIQSIRENKRRVEEQRKRKE-EEERKRKEAEEKA 177
Query: 196 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQEQEQLERN-------KLKQSKE 248
+EQ + ER KL Q K+
Sbjct: 178 KREQELLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQNEKERQLKKEHEAKLLQQKD 237
Query: 249 S-----TNFKLIEETFTKYKTMIQTIKTEIIEPVK-ADPTLKKTLAQHKRKINPKFGQLT 302
TNF I + F YK I IK +I+ P+K AD ++ L++HKRKINPKFGQLT
Sbjct: 238 KLGKAVTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPKFGQLT 297
Query: 303 NSTAQLNAITNELTELVLQTKANQLAYKWILNFIAKAIVSQAESEARVKPEXXXXXXXXX 362
NS QL I NELT+L+ TK + LAY WILNFIAKA+V QAE+E RVKPE
Sbjct: 298 NSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKAVVHQAETEVRVKPESALPLGKLT 357
Query: 363 XXXXXXYPELKEFLLARLIKKCPFVIGYTCSIDTVEGRTRMGWKRQSDNRWEEDISYDER 422
+PEL+E +ARL+KKCPFVIG+TC IDT +GR MGWKR ++N+WE++ SYDER
Sbjct: 358 LYLLVQFPELQELFMARLVKKCPFVIGFTCEIDTEKGRQNMGWKRNNENKWEDNTSYDER 417
Query: 423 MGGMITLFAVITRLPLPQTYIQKLVHPFPISWSWRMLARIGNTPKDLLTNTHFXXXXXXX 482
MGG+++LFA+ITRL LPQ +I HPFPI+ SW +LARI NTP +L+TNTHF
Sbjct: 418 MGGILSLFAIITRLQLPQEFITTTSHPFPIALSWHILARICNTPLNLITNTHFVILGSWW 477
Query: 483 XXXXXXXXXXXXXXXTKLLEVISIDLTALVADKKFVGAARLRIINEEWHNTNQISSFPDM 542
+KLL +I +LT+ +A+KK+VGAARLRI+ E W N N + SFP+M
Sbjct: 478 DAAAVQFLQAYGNQASKLLILIGEELTSRMAEKKYVGAARLRILLEAWQN-NNMESFPEM 536
Query: 543 A 543
+
Sbjct: 537 S 537
>SPBC31E1.05 [A] KOG2412 Nuclear-export-signal (NES)-containing
protein/polyadenylated-RNA export factor
Length = 480
Score = 132 bits (333), Expect = 1e-30
Identities = 128/512 (25%), Positives = 207/512 (40%), Gaps = 77/512 (15%)
Query: 43 IQLKLPKLYHSSKNDGQGEEQGFSSGDTISLEDVVEPEIVSMLSNLNITLERNALPHLTT 102
I KL + SS ND G D L D+ + M+ ++ +
Sbjct: 9 IHAKLDEKIISSYNDANGL-------DIDDLWDIYNEKTRRMIHIISQRYKPKKQSPFPV 61
Query: 103 RGHENKALGPVL---IDEAELYYQEKKDLIDEV---EQHTFPMQDQVLESVWNEEIDSIE 156
EN + P L ID A+ E+++LI++ Q F + ++ + +N E+
Sbjct: 62 IADENVRIFPPLHKTIDWAKKRNVEEQNLIEQSITESQRIFSEKQRLEQERFNREL---- 117
Query: 157 KVNQRLIKSIKDKKKREEEARIQKECEAEKRRQXXXXXXXXXXXXXXXXXXXXXXXXXXX 216
+ ++ I++ + + K EEE R ++ E EK+ +
Sbjct: 118 -LEKKRIEAERQRLKDEEERRKKELMEKEKKEKERIRLIEEQKHKE-------------- 162
Query: 217 XXXXXXXXXXXXXXXXQEQEQLERNKL--KQSKESTNFKLIEETFTKYK--------TMI 266
EQ +L++ ++ K+ +E K ++ETF ++I
Sbjct: 163 ----------------NEQRRLKQEQIDAKRKEEEAREKRMKETFKDDPEEDSNMAWSII 206
Query: 267 QTIKTEIIEPVKADPTLKKTLAQHKRKINPKFGQLTNSTAQLNAITNELTELVLQTK-AN 325
IKTE++ P+ LK KRKI P+ GQ+T S +Q+ IT L + + + +
Sbjct: 207 HKIKTEVVAPISEKKELKNYCFTQKRKITPRLGQITKSNSQIMKITQLLQQTFQEARNTD 266
Query: 326 QLAYKWILNFIAKAIVSQAESEARVKPEXXXXXXXXXXXXXXXYPELKEFLLARLIKKCP 385
L YKW+LNF K++V QAE+E V P +LK+ L ARL K CP
Sbjct: 267 PLVYKWVLNFFCKSVVKQAEAEVAVNPISAYPLAKVCLLLQTQNADLKDLLFARLQKNCP 326
Query: 386 FVIGYTCSIDTVEGRTRMGWKRQSDNRWEEDISYDERMGGMITLFAVITRLPLPQTYIQK 445
+VI + T G+ +MG+K+ SD WE++ +Y+ER G+ ++A I L L + +
Sbjct: 327 WVIPFWYDHGTENGKKKMGFKKLSDGHWEQNTTYNERQCGIFAVYAAI--LSLDDSLAPE 384
Query: 446 LVHPFPISWSWRMLARIGNTP-------KDLLTNTHFXXXXXXXXXXXXXXXXXXXXXXT 498
SWR +R+ N P DL
Sbjct: 385 ---------SWRTFSRLLNLPSPSQLMKSDLELGQTLCSIVSTYLDIAGQSLLRIYGRQA 435
Query: 499 KLLEVISIDLTALVADKKFVGAARLRIINEEW 530
K L V S L A+ RLRI+ E+W
Sbjct: 436 KKLIVCSFSEAYLGANGGGSQYGRLRIVGEDW 467
>Hs4557627 [A] KOG2412 Nuclear-export-signal (NES)-containing
protein/polyadenylated-RNA export factor
Length = 659
Score = 57.4 bits (137), Expect = 5e-08
Identities = 38/132 (28%), Positives = 63/132 (46%), Gaps = 4/132 (3%)
Query: 336 IAKAIVSQAESEARVKPEXXXXXXXXXXXXXXXYPELKEFLLARLIKKCPFVIGYTCSID 395
+A+ V Q E E E +P + + +LA L KKCP+ + + +
Sbjct: 480 LAEKFVKQGEEEVASHHEAAFPIAVVASGIWELHPRVGDLILAHLHKKCPYSVPFYPTFK 539
Query: 396 ---TVEGRTRMGWKRQSDNRWEEDISYDERMGGMITLFAVITRLPLPQTYIQKLVHPFPI 452
+E RM + D++ E+ ++ +RM GMI L+A I +L P Q+ +HP +
Sbjct: 540 EGMALEDYQRMLGYQVKDSKVEQQDNFLKRMSGMIRLYAAIIQLRWPYGNRQE-IHPHGL 598
Query: 453 SWSWRMLARIGN 464
+ WR LA+I N
Sbjct: 599 NHGWRWLAQILN 610
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.314 0.131 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,021,058
Number of Sequences: 60738
Number of extensions: 1051264
Number of successful extensions: 3822
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3806
Number of HSP's gapped (non-prelim): 10
length of query: 544
length of database: 30,389,216
effective HSP length: 111
effective length of query: 433
effective length of database: 23,647,298
effective search space: 10239280034
effective search space used: 10239280034
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)