ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3776 check: MH U KOG1058 Intracellular trafficking, secretion, and vesicular transport Vesicle coat complex COPI, beta subunit
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3776 1331927 1329015 -971
(971 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR238c [U] KOG1058 Vesicle coat complex COPI beta subunit 1279 0.0
Hs7705369 [U] KOG1058 Vesicle coat complex COPI beta subunit 735 0.0
SPBC146.14c [U] KOG1058 Vesicle coat complex COPI beta subunit 729 0.0
7293454 [U] KOG1058 Vesicle coat complex COPI beta subunit 687 0.0
CE21472 [U] KOG1058 Vesicle coat complex COPI beta subunit 672 0.0
At4g31480 [U] KOG1058 Vesicle coat complex COPI beta subunit 667 0.0
At4g31490 [U] KOG1058 Vesicle coat complex COPI beta subunit 663 0.0
ECU08g1100 [U] KOG1058 Vesicle coat complex COPI beta subunit 120 1e-26
At4g11380 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 114 6e-25
At4g23460 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 113 2e-24
HsM4501973 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 109 2e-23
Hs22027653 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 109 2e-23
Hs22027651 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 109 2e-23
7293642 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 106 2e-22
Hs4557469 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 105 3e-22
CE24628 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 103 1e-21
CE18132 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 88 6e-17
SPBC947.02 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 87 1e-16
CE12722 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 86 4e-16
Hs4501975 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 85 6e-16
Hs4758760 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 81 9e-15
Hs18596139 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta ... 79 4e-14
SPCP1E11.06 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 77 2e-13
Hs20127438 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 76 2e-13
SPBC2G2.06c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta... 74 1e-12
CE24044 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 72 5e-12
7292917 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 69 3e-11
Hs4503843 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 65 5e-10
7290497 [U] KOG1060 Vesicle coat complex AP-3 beta subunit 65 7e-10
At1g23900 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit 64 9e-10
SPAC144.06 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 61 7e-09
Hs5729742 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta s... 60 1e-08
YKL135c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta sub... 57 1e-07
YNL287w [U] KOG1078 Vesicle coat complex COPI gamma subunit 56 2e-07
At1g48760 [U] KOG1059 Vesicle coat complex AP-3 delta subunit 54 9e-07
Hs6912320 [U] KOG1078 Vesicle coat complex COPI gamma subunit 54 2e-06
Hs11559929 [U] KOG1078 Vesicle coat complex COPI gamma subunit 53 3e-06
YGR261c [U] KOG1060 Vesicle coat complex AP-3 beta subunit 52 6e-06
7302058 [U] KOG1078 Vesicle coat complex COPI gamma subunit 52 6e-06
>YDR238c [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 973
Score = 1279 bits (3310), Expect = 0.0
Identities = 640/976 (65%), Positives = 805/976 (81%), Gaps = 8/976 (0%)
Query: 1 MTVGVEQPAYTLVYDPNPNGVTYTVSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDL 60
MT QPAYTLV+DP+P+ TY+ +DFQKALEKGSD +KI TMK ILVTML+GNP+P+L
Sbjct: 1 MTSLSSQPAYTLVFDPSPSMETYSSTDFQKALEKGSDEQKIDTMKSILVTMLEGNPMPEL 60
Query: 61 LMHIIRFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRG 120
LMHIIRFVMPSKNK+LKKLLYFYWEIVPKL +GKL+ EMILVCNAIQHDLQHPNEYIRG
Sbjct: 61 LMHIIRFVMPSKNKELKKLLYFYWEIVPKLAEDGKLRHEMILVCNAIQHDLQHPNEYIRG 120
Query: 121 NTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVID 180
NTLRFLTKL+EAELLEQMVPSV ACLEYRHAYVRKYAILAV SI+KVS+HL+PDA E+I+
Sbjct: 121 NTLRFLTKLREAELLEQMVPSVLACLEYRHAYVRKYAILAVFSIFKVSEHLLPDAKEIIN 180
Query: 181 SFLVAETDPICKRNAFLGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKT 240
SF+VAETDPICKRNAF+GLAELDRE AL+YL++N+ IENLD LLQ F+ FIR+DA +T
Sbjct: 181 SFIVAETDPICKRNAFIGLAELDRENALHYLENNIADIENLDPLLQAVFVQFIRQDANRT 240
Query: 241 PGLVSQYVELLQDLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNI 300
P L +QY+ELL +LL +T S +V++E A+ LTVL+ +L+ NKLIDLA K SDNNI
Sbjct: 241 PALKAQYIELLMELLSTTTSDEVIFETALALTVLSANPNVLVPAVNKLIDLAVKVSDNNI 300
Query: 301 KLVVLEKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKL 360
KL+VL++I +IN N G+LE+LTLDILRVLNA+DLDVR+KALDIS++L TSRN + VV+L
Sbjct: 301 KLIVLDRIQDINANNVGALEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQL 360
Query: 361 LRKELQSTADS-SNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESAND 419
L+KELQ+T ++ DK ++YRQLLIK+I VA+ F+E++++VVSLLLDFIG+L+S +A+
Sbjct: 361 LKKELQTTVNNPDQDKAMQYRQLLIKTIRTVAVNFVEMAASVVSLLLDFIGDLNSVAASG 420
Query: 420 VISFTKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHI 479
+I+F K+VIE+YP+LR+ IL +++TL +V+SAKAYRGALW++GE+A+ E+EIQ+ WKHI
Sbjct: 421 IIAFIKEVIEKYPQLRANILENMVQTLDKVRSAKAYRGALWIMGEYAEGESEIQHCWKHI 480
Query: 480 RSSIGEVPIVQSELRRV---QNDDEDDTEKAPIVSTGPVVLPDGTYATESALSVSEKVKS 536
R+S+GEVPI+QSE++++ Q E++ A TGPV+LPDGTYATESA V KS
Sbjct: 481 RNSVGEVPILQSEIKKLTQNQEHTEENEVDATAKPTGPVILPDGTYATESAFDVKTSQKS 540
Query: 537 TSNEEKEARPPLRRFVLNGDFFTASVLANSIVKLVLKFEKISKNTSVTNALKAEGLLILV 596
++EE+++RPP+RRFVL+GDF+TA++LAN+I+KLVLKFE +SKN +V NALKAE LLILV
Sbjct: 541 VTDEERDSRPPIRRFVLSGDFYTAAILANTIIKLVLKFENVSKNKTVINALKAEALLILV 600
Query: 597 SIIRLGQSNLVEKKIDEDSAERLMTAISVLMDEISTEESQAEKELLSLAFLEATNESYKS 656
SI+R+GQS+LVEKKIDEDS ER+MT+IS+L+DE++ EE + E +LL +AFL+ T S+K
Sbjct: 601 SIVRVGQSSLVEKKIDEDSLERVMTSISILLDEVNPEEKKEEVKLLEVAFLDTTKSSFKR 660
Query: 657 RVNVTLKKNAAKRS-NYLAKHAEAIDKSIVFRQFKNAGLHNTPVDSIEEDIKLATTGTVS 715
++ + KKN KR+ K+ E ID I FRQF N DSIEED++LA G
Sbjct: 661 QIEIA-KKNKHKRALKDSCKNIEPIDTPISFRQFAGVDSTNVQKDSIEEDLQLAMKGDAI 719
Query: 716 YSKLQANSITSKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQF 775
++ ++S SKLKKIVPL GFSDPVYAE ITN+QFDVVLDVLLVNQTK+TLKNLHVQF
Sbjct: 720 HA--TSSSSISKLKKIVPLCGFSDPVYAEACITNNQFDVVLDVLLVNQTKETLKNLHVQF 777
Query: 776 ATLGDLKIIDHPPSTNVIPHGFHKITITAKVSSADTGVIFGNIIYDGGHGQDSRYVILND 835
ATLGDLKIID P TNVIPHGFHK T+T KVSSADTGVIFGNIIYDG HG+D+RYVILND
Sbjct: 778 ATLGDLKIIDTPQKTNVIPHGFHKFTVTVKVSSADTGVIFGNIIYDGAHGEDARYVILND 837
Query: 836 VHIDTMDYVKPAICDDNSFRKMWNAFEWENKLRIKSKLPSLRGYLEKLVEVTHMKVLTPE 895
VH+D MDY+KPA DD FR MWNAFEWENK+ +KS+LP+L YL +LV+ T+M +LTP
Sbjct: 838 VHVDIMDYIKPATADDEHFRTMWNAFEWENKISVKSQLPTLHAYLRELVKGTNMGILTPS 897
Query: 896 EALGDNDSRFLSCNLYSRSTFGEDALANLCIEKDPITQEIVGEIRIRSKTQGLALTNGDN 955
E+LG++D RFLSCNLY++S+FGEDALANLCIEKD T +++G +RIRSK QGLAL+ GD
Sbjct: 898 ESLGEDDCRFLSCNLYAKSSFGEDALANLCIEKDSKTNDVIGYVRIRSKGQGLALSLGDR 957
Query: 956 ITRMGRTMNIVSVDRV 971
+ + + N +++ V
Sbjct: 958 VALIAKKTNKLALTHV 973
>Hs7705369 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 953
Score = 735 bits (1898), Expect = 0.0
Identities = 409/968 (42%), Positives = 616/968 (63%), Gaps = 45/968 (4%)
Query: 6 EQPAYTLVYDPNPNGVTYTVSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHII 65
E YTL+ P + +S + LEKG K +K++++ +L+G LP LLM II
Sbjct: 5 ENVCYTLINVPMDSEPPSEIS-LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTII 63
Query: 66 RFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRF 125
RFV+P ++ +KKLL +WEIVPK +G+L EMILVC+A + DLQHPNE+IRG+TLRF
Sbjct: 64 RFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRF 123
Query: 126 LTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVA 185
L KLKEAELLE ++P++RACLE+RH+YVR+ A+LA+ +IY+ +HLIPDA E+I FLV
Sbjct: 124 LCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVN 183
Query: 186 ETDPICKRNAFLGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVS 245
E D CKRNAF+ L D++ AL+YL + ++ +LQ + I K P +
Sbjct: 184 EKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERA 243
Query: 246 QYVELLQDLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVL 305
+++ + +LL S+ S V YEAA TL L++ + A IDL KESDNN+KL+VL
Sbjct: 244 RFIRCIYNLLQSS-SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVL 302
Query: 306 EKINEINE--KNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRK 363
+++ E+ E + L+DL +DILRVL+ DL+VR K L ++L+L++SRNV+ +V +L+K
Sbjct: 303 DRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKK 362
Query: 364 ELQSTAD-SSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVIS 422
E+ T + S ++ T +YRQLL+++++ ++RF ++++NV+ +L++F+ + + +A DV+
Sbjct: 363 EVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLE 422
Query: 423 FTKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSS 482
F ++ I+R+ LR I+ ++E H +KS K YRGALW+LGE+ ++ +IQ+ IR S
Sbjct: 423 FVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIRRS 482
Query: 483 IGEVPIVQSELRRVQNDDEDDTEKAPIVSTGPV---VLPDGTYATESALSVSEKVKSTSN 539
+GE+PIV+SE+++ + + + E ++ GPV V GTYAT+SALS S K
Sbjct: 483 LGEIPIVESEIKKEAGELKPEEE----ITVGPVQKLVTEMGTYATQSALSSSRPTK---- 534
Query: 540 EEKEARPPLRRFVLNGDFFTASVLANSIVKLVLKFEKISKNTSVTNALKAEGLLILVSII 599
++E RPPLR F+L+GDFF A+ LA ++ K+ L++ + + N+ AE +L++ +I+
Sbjct: 535 -KEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATIL 593
Query: 600 RLGQSNLVEKKIDEDSAERLMTAISV------LMDEISTEESQAEKELLSLAFLEATNES 653
LG+S+L +K I +D +R+ + V LM++I +E + + A LE
Sbjct: 594 HLGKSSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLE----- 648
Query: 654 YKSRVNVTLKKNAAKRSNYLAKHAEAIDKSIVFRQFKNAGLHNTPVDSIEEDIKLATTGT 713
++ KK + KR+ + D I F Q N D + + LA G
Sbjct: 649 ---EEKLSQKKESEKRNVTVQP-----DDPISFMQLTAKNEMNCKEDQFQLSL-LAAMGN 699
Query: 714 VSYSKLQANSITSKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHV 773
+ K A+ + SKL K+ LTGFSDPVYAE Y+ +Q+D+VLDVL+VNQT DTL+N +
Sbjct: 700 -TQRKEAADPLASKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTL 758
Query: 774 QFATLGDLKIIDHPPSTNVIPHGFHKITITAKVSSADTGVIFGNIIYD-GGHGQDSRYVI 832
+ ATLGDLK+++ P + PH F I KV+S + G+IFGNI+YD G D V+
Sbjct: 759 ELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVV 818
Query: 833 LNDVHIDTMDYVKPAICDDNSFRKMWNAFEWENKLRIKSKLPSLRGYLEKLVEVTHMKVL 892
L+D+HID MDY++PA C D FR+MW FEWENK+ + + + L YL+ +++ T+MK L
Sbjct: 819 LSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCL 878
Query: 893 TPEEALGDNDSRFLSCNLYSRSTFGEDALANLCIEKDPITQ----EIVGEIRIRSKTQGL 948
TPE+AL F++ NLY+RS FGEDALAN+ IEK PI Q + G IRIR+K+QG+
Sbjct: 879 TPEKAL-SGYCGFMAANLYARSIFGEDALANVSIEK-PIHQGPDAAVTGHIRIRAKSQGM 936
Query: 949 ALTNGDNI 956
AL+ GD I
Sbjct: 937 ALSLGDKI 944
>SPBC146.14c [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 940
Score = 729 bits (1881), Expect = 0.0
Identities = 410/942 (43%), Positives = 608/942 (64%), Gaps = 32/942 (3%)
Query: 24 TVSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFY 83
+V + +LE +D KI+ MK IL +++G+ LP +LMH+IRFVMPS+NK+LKKLLY+Y
Sbjct: 16 SVDALKTSLESKNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMPSRNKELKKLLYYY 75
Query: 84 WEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVR 143
WE+ PK + +G +KQEMIL CN+ ++DLQHPNE+IRG TLRFL KLKE ELL+ ++P+VR
Sbjct: 76 WEVCPKYNNDGTMKQEMILACNSFRNDLQHPNEFIRGATLRFLCKLKEPELLDPLIPTVR 135
Query: 144 ACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELD 203
CLE+RHAYVRK AILAV SIY+VS+HLIPDA + + FL AE++ CKRNA + L +D
Sbjct: 136 QCLEHRHAYVRKNAILAVFSIYQVSNHLIPDAASLAEDFLAAESEGTCKRNALIVLFTID 195
Query: 204 REAALNYLQDNLTSIENLDALLQNAFISFIRKDAI-KTPGLVSQYVELLQDLLVSTRSTD 262
E A +L N I +L+A I FIRK + K GL + L L +T ++
Sbjct: 196 PEKAKAWLLANFEQIPSLNASSLLVIIEFIRKVVLTKADGLEKLRFQSLLVSLTATNNSS 255
Query: 263 VMYEAAIT-LTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLED 321
V++EAA + + V + E++ L A++L+ LA +E+DNN KL++L++I+++ ++ LED
Sbjct: 256 VVFEAATSVINVFPDAESLKL-AASRLLALADREADNNAKLIMLDRISQLAARDKSILED 314
Query: 322 LTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQ 381
L D++ L++ D DV KA+ I + L++SRNV+ ++ +KEL + ++ +K R+
Sbjct: 315 LITDVIPFLSSSDFDVCEKAISIIMGLVSSRNVEDILNHFQKEL-TKSNGETEKDDGRRR 373
Query: 382 LLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPELRSEILTT 441
L K+I+ AI F ++ + LL I + S+SA+ V+SF K+V+E++P+LRS +T
Sbjct: 374 ALTKAIHSCAINFPHTAATAIQYLLSHISDFQSKSASSVLSFIKEVMEKFPDLRSSNITK 433
Query: 442 LIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGEVPIVQSE---LRRVQN 498
L+ +L E+++ K +RG +W+ GE+ +E +I+ WK IR+S+GEVPI+ SE L+ V N
Sbjct: 434 LLLSLKELRAGKIFRGVIWIAGEYCLTEDDIRVAWKSIRASLGEVPILASEEQLLKDVSN 493
Query: 499 DDEDD--TEKAPIVSTGPVVLPDGTYATESALSVSEKVKSTSNEEKEA--RPPLRRFVLN 554
EDD + + ST VLPDGTYATESA++ SE + + E +A +PPLR +L+
Sbjct: 494 VPEDDLLIDISAPASTSRKVLPDGTYATESAVT-SEALSAARLEAVKASKKPPLRTQILS 552
Query: 555 GDFFTASVLANSIVKLVLKFEKISKNTSVTNALKAEGLLILVSIIRLGQSNLVEKKIDED 614
GD++ A+VLA+++ KLV++F ++S + NALKAE LI+ SIIR+GQS V+ ID+D
Sbjct: 553 GDYYLAAVLASALTKLVMRFARLSFDKERLNALKAEACLIMTSIIRVGQSKFVKYTIDDD 612
Query: 615 SAERLMTAISVLMDEISTEESQAEKELLSLAFLEATNESYKSRVNVTLKKNAAKRSNYLA 674
S ER+M I + E Q FL+ +++ S V + K+ K ++ L
Sbjct: 613 SVERIMNCIRAIYSFEELPEFQT-------VFLDDMRKAFSSLVAQSDKRQ--KEADLLV 663
Query: 675 KHAEAI--DKSIVFRQFKNAGLHNTPVDSIEEDIKLATTGTVSYSKLQANSITSKLKKIV 732
++A+ D+ + RQF+ + + E DI AT + + SKL IV
Sbjct: 664 NGSDAVQADELLNIRQFQRV-IEEKQDLNFESDIIQATN-----DGMVVEDLASKLDHIV 717
Query: 733 PLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQFATLGDLKIIDHPPSTNV 792
L GF+DPVY E Y+ QFD++LD+LLVN+T TL+NL V ATLGDLK+++ PP N+
Sbjct: 718 QLAGFTDPVYCEAYVKIQQFDIILDILLVNRTDTTLQNLSVDLATLGDLKVVERPPPMNL 777
Query: 793 IPHGFHKITITAKVSSADTGVIFGNIIYDGGHGQDSRYVILNDVHIDTMDYVKPAICDDN 852
PH F + T KVSS ++ VIFGNI+Y G + + V+LN + ++ +DY+KPA ++
Sbjct: 778 GPHAFKSVQATVKVSSTESAVIFGNIVYGGKASDEDKIVVLNGIPVNIIDYIKPAFIPES 837
Query: 853 SFRKMWNAFEWENKLRIKSKLP-SLRGYLEKLVEVTHMKVLTPEEALGDNDSRFLSCNLY 911
FR MW FEWENK+ I S SL +L K+++ T+M LTP+ +L D FLS NLY
Sbjct: 838 QFRSMWTEFEWENKVDISSNEDISLYDFLHKIMKKTNMNCLTPDASL-RGDCGFLSANLY 896
Query: 912 SRSTFGEDALANLCIEKDPITQEIVGEIRIRSKTQGLALTNG 953
+ S FGEDAL +L +EK ++ I G +RIRSKTQG+AL+ G
Sbjct: 897 ACSIFGEDALMSLSVEKS-VSGPISGHVRIRSKTQGIALSLG 937
>7293454 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 963
Score = 687 bits (1772), Expect = 0.0
Identities = 382/970 (39%), Positives = 593/970 (60%), Gaps = 42/970 (4%)
Query: 8 PAYTLVYDPNPNGVTYTVSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRF 67
P YT++ P+ VT + ++ LEKG KI T+KR++ +L+G P L+M IIRF
Sbjct: 6 PCYTIINSPDLE-VTNEMQ-LKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRF 63
Query: 68 VMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLT 127
V+P +N +KKLL +WEIVPK +GKL QEMILVC+A + DLQHPNE++RG+TLRFL
Sbjct: 64 VLPVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLC 123
Query: 128 KLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVAET 187
KLKE ELLE ++P++RACL++RH+YVR+ A+LA+ +IYK D L+PD E+I SFL +
Sbjct: 124 KLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQ 183
Query: 188 DPICKRNAFLGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQY 247
D CKRNAFL L D+E ALNYL + + +LQ + I K P S++
Sbjct: 184 DMSCKRNAFLMLLHADQERALNYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRF 243
Query: 248 VELLQDLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEK 307
+ + +LL S+ S V YE+A TL L+ + A+ I+L KESDNN+KL+VL++
Sbjct: 244 IRCIYNLLNSS-SNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDR 302
Query: 308 INEINEKN--PGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKEL 365
+ + E ++DL +D+LRVL A D++VR K L ++L+L+ SRN+ +V +L+KE+
Sbjct: 303 LVAMKEHEGMEKVMQDLVMDVLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEV 362
Query: 366 QSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTK 425
T + ++ T +YRQLL+++++ +I+F +V++NV+ +L++F+ + + +A DV+ F +
Sbjct: 363 AKTHNVEHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIR 422
Query: 426 QVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGE 485
+ I+++P LR+ I+ LIE ++KS+K +R A+W+LGE+ + ++I I+ ++GE
Sbjct: 423 EAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWILGEYVEG-SQILEVIAVIQQTLGE 481
Query: 486 VPIVQSELRRVQNDDEDDTEKAPIVSTGPV----------------VLPDGTYATESALS 529
VP+V++E RR+ D ++ ++ + G V DGTYAT+SA S
Sbjct: 482 VPMVEAEQRRLAGDQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYS 541
Query: 530 VSEKVKSTSNEEKEARPPLRRFVLNGDFFTASVLANSIVKLVLKFEKISKNTSVTNALKA 589
++ K+ E RPPLR+++++GDFF + L+ ++ KL L++ ++ N L
Sbjct: 542 LAPVAKA------EKRPPLRQYLMDGDFFIGAALSATLTKLALRYAELETEARAQNRLTT 595
Query: 590 EGLLILVSIIRLGQSNLVEKKIDEDSAERLMTAISVLMDEISTEESQAEKELLSLAFLEA 649
+ +LI+ SI+ LG+S K I D +R+ + L +E + + +L EA
Sbjct: 596 QVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTL-----SERTPEAISVFTLYCREA 650
Query: 650 TNESYKSRVNVTLKKNAAKRSNYLAKHAEAIDKSIVFRQFKNAGLHNTPVDSIEEDIKLA 709
+ ++ + + K+ A D ++F Q N + + E + A
Sbjct: 651 LGKMLDAQHDEDQRMLKEKQK---ATAKVQPDDPVLFAQLSNGRDNQLGENVFESSLNQA 707
Query: 710 TTGTVSYSKLQANSITSKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLK 769
G+ + S SKL K+ LTGFSDPVYAE Y+ +Q+D+VLDVL+VNQT DTL+
Sbjct: 708 LAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQ 767
Query: 770 NLHVQFATLGDLKIIDHPPSTNVIPHGFHKITITAKVSSADTGVIFGNIIYDGGHGQDSR 829
N ++ ATLGDLK+++ P + PH F I KVSS + G+IFGNI+Y+ ++
Sbjct: 768 NCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYE--TALNTN 825
Query: 830 YVILNDVHIDTMDYVKPAICDDNSFRKMWNAFEWENKLRIKSKLPSLRGYLEKLVEVTHM 889
V+LN +HID MDY+ PA C D FR+MW FEWENK+ + + L YL+ L++ T+M
Sbjct: 826 VVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLKHLLKSTNM 885
Query: 890 KVLTPEEALGDNDSRFLSCNLYSRSTFGEDALANLCIEK--DPITQEIVGEIRIRSKTQG 947
K LTPE+AL F++ N+Y++S FGE+ALANL IEK D ++ G IRIR+K+ G
Sbjct: 886 KCLTPEKAL-SGQCGFMAANMYAKSIFGENALANLSIEKPVDDPDSKVTGHIRIRAKS-G 943
Query: 948 LALTNGDNIT 957
+AL+ GD I+
Sbjct: 944 MALSLGDKIS 953
>CE21472 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 971
Score = 672 bits (1733), Expect = 0.0
Identities = 381/968 (39%), Positives = 597/968 (61%), Gaps = 24/968 (2%)
Query: 6 EQPAYTLVYDPNPNGVTYTVSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPD-LLMHI 64
EQP YTL++ P+ + + + ++ EKG D E+I +K+++ +L+G +LM++
Sbjct: 5 EQPCYTLIHVPSDAELP-SEAQLKEKFEKGGDKERIEALKKLIYMILNGEKTSQSMLMYV 63
Query: 65 IRFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLR 124
IRF +PS LKK+L +WE VPK D GKL EMILVC+A + DLQHPNE++RG+TLR
Sbjct: 64 IRFCLPSNEHTLKKVLLIFWECVPKTDSNGKLLHEMILVCDAYRKDLQHPNEFVRGSTLR 123
Query: 125 FLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLV 184
FL KL+E ELLE ++P++RACLE+RH+YVR+ A+ A+ +IYK + LIPDA E++ +L
Sbjct: 124 FLCKLREPELLEPLMPAIRACLEHRHSYVRRNAVCAIFTIYKNFEFLIPDAPELVTEYLE 183
Query: 185 AETDPICKRNAFLGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLV 244
E D CKRNAF+ L +D+ AL+YL + + + +LQ + I K P
Sbjct: 184 QEQDASCKRNAFMMLLHVDQARALDYLSGCIDQVGSFGDILQLVIVELIYKVCHNNPNEA 243
Query: 245 SQYVELLQDLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVV 304
S+++ + +LL S+ S V YEAA TL L+N A + A+ IDL KESDNN+KL+V
Sbjct: 244 SRFIRCVYNLLQSS-SPAVRYEAAGTLVTLSNVPAAVKAAASAYIDLIVKESDNNVKLIV 302
Query: 305 LEKINEI--NEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLR 362
L+++ + + N L+ L +DILRVL++ L+VR K L ++L+L++SRNV+ +V L+
Sbjct: 303 LDRLVALRGSSSNEKILQGLVMDILRVLSSPGLEVRKKTLSLALDLVSSRNVEDMVMFLK 362
Query: 363 KELQSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVIS 422
KE+ TA SND+ +YRQ L+K+++ I+F +V+S +V +L++F+ + + ++++ V+
Sbjct: 363 KEINKTATESNDENGKYRQELVKTLHAATIKFPDVASTIVPVLMEFLSDTNEKASSYVLQ 422
Query: 423 FTKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSS 482
F ++ + + P L++ IL L E + ++S + ALW+L + +++ + + K +++S
Sbjct: 423 FVREAVHKLPNLKNAILGALREGIPFIQSPTIFMSALWILATYCEADGAL-DVLKLVKNS 481
Query: 483 IGEVPIVQSELRRVQNDDEDDTEKAPIVSTGPVVLPDGTYATESALSVSEKVKSTSNEEK 542
+GE+P+V SEL + ++ + P V DGTYAT++ALS + + +K
Sbjct: 482 LGELPLVDSELSGQEEQKPEEQQPEQQQKQKPKVTADGTYATQTALS-----STVTTSKK 536
Query: 543 EARPPLRRFVLNGDFFTASVLANSIVKLVLKFEKISKNTSV-TNALKAEGLLILVSIIRL 601
+PPLRRF+L+G+FF + LA + KL +F +++ S N +AE +LIL SII L
Sbjct: 537 NEKPPLRRFLLDGEFFLGASLATVLTKLAQQFTELNGAASERANRFRAECMLILSSIIHL 596
Query: 602 GQSNL--VEKKIDEDSAERLMTAISVLMDEISTEESQAEKELLSLAFLEATNESYKSRVN 659
+S L V ++++ED +R+ I +L I + Q + L +S SR++
Sbjct: 597 AKSGLCIVHQQVNEDDLDRMGATIKILAQGIPGLDEQYGDDCKKSLELMLGAKSI-SRLD 655
Query: 660 VTLKKNAA-KRSNYLAKHAEAIDKSIVFRQFKNAGLHNTPVDSIEEDIKLATTGTVSYSK 718
VT +K A+ + Y +K IDK+I F Q + N +++ D+ L+ +
Sbjct: 656 VTTEKMASTTAAGYRSKDFVEIDKTINFTQL--SARSNQQGENL-FDLSLSQALGTAPKA 712
Query: 719 LQANSITSKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQFATL 778
+ + +SKL K++ L GFSDP+YAE Y+ +Q+D+VLDVL+VNQT DTL+N+ ++ AT+
Sbjct: 713 QKFDFSSSKLGKVIQLAGFSDPIYAEAYVNVNQYDIVLDVLIVNQTSDTLQNVSLELATV 772
Query: 779 GDLKIIDHPPSTNVIPHGFHKITITAKVSSADTGVIFGNIIYD-GGHGQDSRYVILNDVH 837
GDLK++D P + P+ F I T KV+S + GVIF I YD G D V L D+
Sbjct: 773 GDLKLVDKPTPVTLAPNDFSNIKATVKVASTENGVIFSTISYDVTGSTSDRNCVYLQDIK 832
Query: 838 IDTMDYVKPAICDDNSFRKMWNAFEWENKLRIKSKLPSLRGYLEKLVEVTHMKVLTPEEA 897
ID MDY+ P D FR MW+ FEWENK+ + + + LR +L L T+MKVLT + A
Sbjct: 833 IDIMDYIVPGNVTDTEFRTMWSDFEWENKVNVMTPIRDLRDFLNHLSTSTNMKVLTGDAA 892
Query: 898 LGDNDSRFLSCNLYSRSTFGEDALANLCIEKD-PI--TQEIVGEIRIRSKTQGLALTNGD 954
+ + D FL+ NL + S FGEDALAN+ +EK P+ + IVG IRIR+K+QG+ LT GD
Sbjct: 893 I-EGDCGFLAANLCAHSIFGEDALANVSVEKALPMDDSSPIVGHIRIRAKSQGMCLTLGD 951
Query: 955 NITRMGRT 962
++ R+
Sbjct: 952 KLSSAMRS 959
>At4g31480 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 971
Score = 667 bits (1721), Expect = 0.0
Identities = 370/946 (39%), Positives = 585/946 (61%), Gaps = 26/946 (2%)
Query: 20 GVTYTVSDFQKALEKGSDTE-KIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKK 78
G ++ ++ALE G+D E K+ MK+ ++ +L+G +P L + IIR+V+PS++ ++K
Sbjct: 37 GTPAVANEIKEALE-GNDVEAKVDAMKKAIMLLLNGETIPQLFITIIRYVLPSEDHTIQK 95
Query: 79 LLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQM 138
LL Y E++ K D +GK+ EMIL+C ++++LQHPNEYIRG TLRFL ++KE E++E +
Sbjct: 96 LLLLYLELIEKTDSKGKVLPEMILICQNLRNNLQHPNEYIRGVTLRFLCRMKETEIVEPL 155
Query: 139 VPSVRACLEYRHAYVRKYAILAVLSIYKV--SDHLIPDACEVIDSFLVAETDPICKRNAF 196
PSV LE+RH +VR+ AILA++SIYK+ D L DA E+I+ L E DP KRNAF
Sbjct: 156 TPSVLQNLEHRHPFVRRNAILAIMSIYKLPQGDQLFVDAPEMIEKVLSTEQDPSAKRNAF 215
Query: 197 LGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLV 256
L L E A+NYL N+ + + + LQ + IR P +Y++++ LL
Sbjct: 216 LMLFTCAEERAVNYLLSNVDKVSDWNESLQMVVLELIRSVCKTKPAEKGKYIKIIISLLS 275
Query: 257 STRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNP 316
+T S V+YE A TL L++ + AN L +SDNN+KL++L+++ E+ +
Sbjct: 276 ATSSA-VIYECAGTLVSLSSAPTAIRAAANTYCQLLLSQSDNNVKLILLDRLYELKTLHR 334
Query: 317 GSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKT 376
+ +L +D+LR L++ +LD+R K LDISL+LIT N++ VV++L+KE+ T +K
Sbjct: 335 DIMVELIIDVLRALSSPNLDIRRKTLDISLDLITHHNINEVVQMLKKEVVKTQSGELEKN 394
Query: 377 LEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPELRS 436
EYRQ+LI++I+ A++F EV+S VV LL+DF+G+ + SA DV+ F +++IE P+LR
Sbjct: 395 GEYRQMLIQAIHACAVKFPEVASTVVHLLMDFLGDSNVASALDVVVFVREIIETNPKLRV 454
Query: 437 EILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGEVPI--VQSELR 494
I+T L++T +++++ K ALW++GE+ S +E+++ I +GE+P V E
Sbjct: 455 SIITRLLDTFYQIRAGKVCPCALWIIGEYCLSLSEVESGISTITQCLGELPFYSVSEESE 514
Query: 495 RVQNDDE-DDTEKAPIVSTGPVVLPDGTYATESALSVSEKVKSTSNEEKEARPPLRRFVL 553
+ + T A + S PV+L DGTYAT+SA S + T + LR +L
Sbjct: 515 PTETSKKIQPTSSAMVSSRKPVILADGTYATQSAASETTFSSPTVVQGSLTSGNLRALLL 574
Query: 554 NGDFFTASVLANSIVKLVLKFEKISKNTSVTNALKAEGLLILVSIIRLGQSNLVEKKIDE 613
GDFF +V+A ++ KLVL+ E++ + + N + LLI+VS+++LGQS + ID
Sbjct: 575 TGDFFLGAVVACTLTKLVLRLEEVQSSKTEVNKTVTQALLIMVSMLQLGQSPVSPHPIDN 634
Query: 614 DSAERLMTAISVLMDEISTEESQAEKELLSLAFLEATNESYKSRVNVT-LKKNAAKRSNY 672
DS ER++ I +L + + +LE+ +S+ ++ L++ ++
Sbjct: 635 DSYERIVLCIKLLCHR---------NDEMKKIWLESCRQSFVKMISEKQLREMEELKAKT 685
Query: 673 LAKHAEAIDKSIVFRQFKNAGLHNTPV-DSIEEDIKLATTGTVSYSKLQANSITSKLKKI 731
HA+ D F G+ + D +++D+K AT G + + AN KL +I
Sbjct: 686 QTTHAQPDDLIDFFHLKSRKGMSQLELEDQVQDDLKRAT-GEFTKDENDAN----KLNRI 740
Query: 732 VPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQFATLGDLKIIDHPPSTN 791
+ LTGFSDPVYAE Y+T H +D+ L+V ++N+TK+TL+NL ++ AT+GDLK+++ P + +
Sbjct: 741 LQLTGFSDPVYAEAYVTVHHYDIALEVTVINRTKETLQNLCLELATMGDLKLVERPQNYS 800
Query: 792 VIPHGFHKITITAKVSSADTGVIFGNIIYDGGHGQDSRYVILNDVHIDTMDYVKPAICDD 851
+ P +I KVSS +TGVIFGNI+Y+ + + V+LND+HID MDY+ PA+C +
Sbjct: 801 LAPERSMQIKANIKVSSTETGVIFGNIVYETSNVMERNVVVLNDIHIDIMDYISPAVCSE 860
Query: 852 NSFRKMWNAFEWENKLRIKSKLPSLRGYLEKLVEVTHMKVLTPEEALGDNDSRFLSCNLY 911
+FR MW FEWENK+ + + + + R +L+ +++ T+MK LT A+ + + FL+ NLY
Sbjct: 861 VAFRTMWAEFEWENKVAVNTTIQNEREFLDHIIKSTNMKCLTAPSAI-EGECGFLAANLY 919
Query: 912 SRSTFGEDALANLCIEKDPITQEIVGEIRIRSKTQGLALTNGDNIT 957
++S FGEDAL N+ IEK + G IRIRSKTQG+AL+ GD IT
Sbjct: 920 AKSVFGEDALVNVSIEKQ-TDGALSGYIRIRSKTQGIALSLGDKIT 964
>At4g31490 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 958
Score = 663 bits (1711), Expect = 0.0
Identities = 374/952 (39%), Positives = 585/952 (61%), Gaps = 28/952 (2%)
Query: 20 GVTYTVSDFQKALEKGSDTE-KIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKK 78
G ++ ++ALE G+D E K+ MK+ ++ +L+G +P L + IIR+V+PS++ ++K
Sbjct: 14 GTPAVANEIKEALE-GNDVEAKVDAMKKAIMLLLNGETIPQLFITIIRYVLPSEDHTIQK 72
Query: 79 LLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQM 138
LL Y E++ K D +GK+ EMIL+C ++++LQHPNEYIRG TLRFL ++KE E++E +
Sbjct: 73 LLLLYLELIEKTDSKGKVLPEMILICQNLRNNLQHPNEYIRGVTLRFLCRMKETEIVEPL 132
Query: 139 VPSVRACLEYRHAYVRKYAILAVLSIYKV--SDHLIPDACEVIDSFLVAETDPICKRNAF 196
PSV LE+RH +VR+ AILA++SIYK+ D L DA E+I+ L E DP KRNAF
Sbjct: 133 TPSVLQNLEHRHPFVRRNAILAIMSIYKLPHGDQLFVDAPEMIEKVLSTEQDPSAKRNAF 192
Query: 197 LGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLV 256
L L E A+NYL N+ + + + LQ + IR P +Y++++ LL
Sbjct: 193 LMLFTCAEERAVNYLLSNVDKVSDWNESLQMVVLELIRSVCKTKPAEKGKYIKIIISLLS 252
Query: 257 STRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNP 316
+T S V+YE A TL L++ + AN L +SDNN+KL++L+++ E+ +
Sbjct: 253 ATSSA-VIYECAGTLVSLSSAPTAIRAAANTYCQLLLSQSDNNVKLILLDRLYELKTLHR 311
Query: 317 GSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKT 376
+ +L +D+LR L++ +LD+R K LDI+L+LIT N++ VV++L+KE+ T +K
Sbjct: 312 DIMVELIIDVLRALSSPNLDIRRKTLDIALDLITHHNINEVVQMLKKEVVKTQSGELEKN 371
Query: 377 LEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPELRS 436
EYRQ+LI++I+ A++F EV+S VV LL+DF+G+ + SA DV+ F +++IE P+LR
Sbjct: 372 GEYRQMLIQAIHACAVKFPEVASTVVHLLMDFLGDSNVASALDVVVFVREIIETNPKLRV 431
Query: 437 EILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGEVPI--VQSELR 494
I+T L++T +++++ K ALW++GE+ S +E+++ I +GE+P V E
Sbjct: 432 SIITRLLDTFYQIRAGKVCPCALWIIGEYCLSLSEVESGISTITQCLGELPFYSVSEESE 491
Query: 495 RVQNDDE-DDTEKAPIVSTGPVVLPDGTYATESALSVSEKVKSTSNEEKEARPPLRRFVL 553
+ + T A + S PV+L DGTYAT+SA S + T + LR +L
Sbjct: 492 PTETSKKIQPTSSAMVSSRKPVILADGTYATQSAASETTFSSPTVVQGSLTSGNLRALLL 551
Query: 554 NGDFFTASVLANSIVKLVLKFEKISKNTSVTNALKAEGLLILVSIIRLGQSNLVEKKIDE 613
GDFF +V+A ++ KLVL+ E++ + + N ++ LLI+VSI++LGQS + ID
Sbjct: 552 TGDFFLGAVVACTLTKLVLRLEEVQSSKTEVNKTVSQALLIMVSILQLGQSPVSPHPIDN 611
Query: 614 DSAERLMTAISVLMDEISTEESQAEKELLSLAFLEATNESYKSRVNVTLKKNAAKRSNYL 673
DS ER+M I +L + E + E +F++ +E +++ AK
Sbjct: 612 DSYERIMLCIKLLCHR-NVEMKKIWLESCRQSFVKMISEKQLRE----MEELKAKTQTTH 666
Query: 674 AKHAEAID--------KSIVFRQFKNAGLHNTPVDSIEEDIKLATTGTVSYSKLQANSIT 725
A+ + ID S++ F D +++D+K AT G + + AN
Sbjct: 667 AQPDDLIDFFHLKSRKMSLLMINFFQGMSQLELEDQVQDDLKRAT-GEFTKDENDAN--- 722
Query: 726 SKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQFATLGDLKIID 785
KL +I+ LTGFSDPVYAE Y+T H +D+ L+V ++N+TK+TL+NL ++ AT+GDLK+++
Sbjct: 723 -KLNRILQLTGFSDPVYAEAYVTVHHYDIALEVTVINRTKETLQNLCLELATMGDLKLVE 781
Query: 786 HPPSTNVIPHGFHKITITAKVSSADTGVIFGNIIYDGGHGQDSRYVILNDVHIDTMDYVK 845
P + ++ P +I KVSS +TGVIFGNI+Y+ + + V+LND+HID MDY+
Sbjct: 782 RPQNYSLAPERSMQIKANIKVSSTETGVIFGNIVYETSNVMERNVVVLNDIHIDIMDYIS 841
Query: 846 PAICDDNSFRKMWNAFEWENKLRIKSKLPSLRGYLEKLVEVTHMKVLTPEEALGDNDSRF 905
PA+C + +FR MW FEWENK+ + + + + R +L+ +++ T+MK LT A+ + F
Sbjct: 842 PAVCSEVAFRTMWAEFEWENKVAVNTTIQNEREFLDHIIKSTNMKCLTAPSAIA-GECGF 900
Query: 906 LSCNLYSRSTFGEDALANLCIEKDPITQEIVGEIRIRSKTQGLALTNGDNIT 957
L+ NLY++S FGEDAL NL IEK + G IRIRSKTQG+AL+ GD IT
Sbjct: 901 LAANLYAKSVFGEDALVNLSIEKQ-TDGTLSGYIRIRSKTQGIALSLGDKIT 951
>ECU08g1100 [U] KOG1058 Vesicle coat complex COPI beta subunit
Length = 818
Score = 120 bits (301), Expect = 1e-26
Identities = 111/460 (24%), Positives = 201/460 (43%), Gaps = 49/460 (10%)
Query: 27 DFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWEI 86
+ + L S+ +KI MK+++ M G L I + + ++ +LK+L Y+Y E+
Sbjct: 17 EIMQKLRSSSEQDKIEGMKQMIAQMSQGEDFSSLTHKITKETLVVRSNELKRLFYYYLEL 76
Query: 87 VPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACL 146
+PK R + +EM+L+ N ++ DL+HPNEY+RG +RF++ L + EL+ ++
Sbjct: 77 LPKA-RGTQSFEEMLLLSNQVRKDLEHPNEYVRGFVMRFVSTLDDQELVGNFYKLIKDNF 135
Query: 147 EYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDREA 206
+ + YVR+ A + I+ D + + +++ L+ + DP C R AF+ L D E
Sbjct: 136 NHPNTYVRRNAYFCLGEIFLKMD-MYKEVPDLLYHALLRDLDPNCLREAFVSLHLTDPEL 194
Query: 207 ALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVSTRSTDVMYE 266
AL Y + SI + L A + I+ + LL+ L S S +E
Sbjct: 195 ALKYAGEVSLSI---PSELSTAIVEKIKDE------------RLLERFLFSEDSM-TAFE 238
Query: 267 AAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINE-------KNPGSL 319
A +++ ++N E +L K S + I L LE + E + S
Sbjct: 239 AGMSIHRMSNDEQLL------------KRSTDTI-LRCLEDLPRCREYAIDELLLSTYSF 285
Query: 320 EDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEY 379
+ L +++ DL +K D ++ + + L T D+S + +
Sbjct: 286 SGYAMSFLSLIDPYDLSFCSKCFDFVFKISETHEFLQISDFLAFRFMDTHDAS-VQNQSF 344
Query: 380 RQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTK---QVIERYPEL-- 434
R LL++ + A + + +VS L I + + E ++ + F +++ R E
Sbjct: 345 RVLLLEKMAYFASTYSSYNEEMVSEALKSIASDNPEMSHASLMFLSSCFEIMSRSSESCE 404
Query: 435 -----RSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSE 469
L L+ ++EVK K R +L HA E
Sbjct: 405 GDAAGHGSYLEVLVNKINEVKYGKILRCCFGILRRHATKE 444
Score = 79.0 bits (193), Expect = 3e-14
Identities = 61/239 (25%), Positives = 117/239 (48%), Gaps = 32/239 (13%)
Query: 725 TSKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQFATLGDLK-- 782
+++++ + LTG SDP+Y E + ++++V+D+L +NQT L+N+ + F T L
Sbjct: 579 SAEMRNVTQLTGLSDPIYVEATTSYTRYEIVVDMLFINQTPSYLQNILLDFVTSQGLSAT 638
Query: 783 IIDHP---PSTNVIPHGFHKITITAKVSSADTGVIFGNIIY----DGGHGQDSRYVI-LN 834
I P S +V+ F T ++ A G I G+I + + G ++ Y I L+
Sbjct: 639 FISTPFSLSSRSVVTKRF-----TFRIIDASNGFISGSITFRYPDECGEYANTVYTINLS 693
Query: 835 DVHIDTMDYVKPAICDDNSFRKMWNAFEWEN----KLRIKSKLPSLRGYLEKLVEVTHMK 890
+V ++++P D + FR+ W EWEN K K L + G + + + +
Sbjct: 694 EVKTSVSEFLEPRKMDPDGFRETWKELEWENTYTLKFITKKTLEEIFGEVSRALNGETLD 753
Query: 891 VLTPEE-ALGDNDSRFLSCNLYSRSTFGEDALANLCIEKDPITQEIVGEIRIRSKTQGL 948
+ E+ A+G+ ++C+ L N+C+ + ++ + E RIRS+ +G+
Sbjct: 754 IECDEDYAVGN-----IACSTLQNVC----VLVNVCLRR---SEHVHFESRIRSRKEGI 800
>At4g11380 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 894
Score = 114 bits (286), Expect = 6e-25
Identities = 104/459 (22%), Positives = 204/459 (43%), Gaps = 34/459 (7%)
Query: 25 VSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYW 84
+ + ++ L ++ +K+++ M G + L ++ M ++N +LKKL+Y Y
Sbjct: 17 IPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVN-CMQTENLELKKLVYLY- 74
Query: 85 EIVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVR 143
L K + ++ IL N D Q PN IR +R + ++ ++ E + ++
Sbjct: 75 -----LINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEYLCDPLQ 129
Query: 144 ACLEYRHAYVRKYAILAVLSIYKVSDHLIPDA--CEVIDSFLVAETDPICKRNAFLGLAE 201
CL+ YVRK A + V ++ ++ L+ D E + L+++ +P+ NA LAE
Sbjct: 130 KCLKDDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKD-LISDNNPMVVANAVAALAE 188
Query: 202 LDREAALNYLQDNLTSIENLDALLQNA-------FISFIRKDAIKTPGLVSQYVELLQDL 254
+ ++ + N T++ L L + + K P VE +
Sbjct: 189 IQENSSSPIFEINSTTLTKLLTALNECTEWGQVFILDALSKYKAADPREAENIVERVTPR 248
Query: 255 LVSTRSTDVMYEAAITLT---VLTNKEAI---LLTVANKLIDLATKESDNNIKLVVLEKI 308
L V+ + L ++T+ + I +A L+ L + E + I+ V L I
Sbjct: 249 LQHANCAVVLSAVKMILQQMELITSTDVIRNLCKKMAPPLVTLLSAEPE--IQYVALRNI 306
Query: 309 NEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQST 368
N I +K P L + + + V+ + L+I ++L + RN+D V+ L KE +
Sbjct: 307 NLIVQKRPTILAH-EIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVL-LEFKEYATE 364
Query: 369 ADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVI 428
D +++ + +++I + AI+ + +S+LL+ I + + I K +
Sbjct: 365 VD------VDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIKDIF 418
Query: 429 ERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
RYP I+ TL E+L + +A +W++GE+A+
Sbjct: 419 RRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAE 457
>At4g23460 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 893
Score = 113 bits (282), Expect = 2e-24
Identities = 103/462 (22%), Positives = 204/462 (43%), Gaps = 40/462 (8%)
Query: 25 VSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYW 84
+ + ++ L ++ +K+++ M G + L ++ M ++N +LKKL+Y Y
Sbjct: 17 IPELKEELNSQYKDKRKDAVKKVIAAMTVGKDVSSLFTDVVN-CMQTENLELKKLVYLY- 74
Query: 85 EIVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVR 143
L K + ++ IL N D Q PN IR +R + ++ ++ E + ++
Sbjct: 75 -----LINYAKSQPDLAILAVNTFVKDSQDPNPLIRALAVRTMGCIRVDKITEYLCDPLQ 129
Query: 144 ACLEYRHAYVRKYAILAVLSIYKVSDHLIPDA--CEVIDSFLVAETDPICKRNAFLGLAE 201
CL+ YVRK A + V ++ ++ L+ D E + L+++ +P+ NA LAE
Sbjct: 130 KCLKDDDPYVRKTAAICVAKLFDINAELVEDRGFLEALKD-LISDNNPMVVANAVAALAE 188
Query: 202 LDREAALNYLQDNLTSIENL-----------DALLQNAFISFIRKDAIKTPGLVSQYVEL 250
+ + + N T + L + +A + D + +V +
Sbjct: 189 IQENSTSPIFEINSTILTKLLTALNECTEWGQVFILDALSRYKASDPREAENIVERVTPR 248
Query: 251 LQD-----LLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVL 305
LQ +L + + E + V+ N + +A L+ L + E + I+ V L
Sbjct: 249 LQHANCAVVLSAVKMILQQMELITSTDVIRN---LCKKMAPPLVTLLSAEPE--IQYVAL 303
Query: 306 EKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKEL 365
IN I +K P L + + + V+ + L+I ++L + RN+D V+ L KE
Sbjct: 304 RNINLIVQKRPTILAH-EIKVFFCKYNDPIYVKMEKLEIMIKLASDRNIDQVL-LEFKEY 361
Query: 366 QSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTK 425
+ D +++ + +++I + AI+ + +S+LL+ I + + I K
Sbjct: 362 ATEVD------VDFVRKAVRAIGRCAIKLERAAERCISVLLELIKIKVNYVVQEAIIVIK 415
Query: 426 QVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+ RYP I+ TL E+L + +A +W++GE+A+
Sbjct: 416 DIFRRYPNTYESIIATLCESLDTLDEPEAKASMIWIIGEYAE 457
>HsM4501973 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 949
Score = 109 bits (272), Expect = 2e-23
Identities = 107/460 (23%), Positives = 205/460 (44%), Gaps = 38/460 (8%)
Query: 28 FQKALEKGSDTE--KIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWE 85
F+ E SD + K +K+++ +M G + L ++ M + N +LKKL+Y Y
Sbjct: 16 FELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNLELKKLVYLY-- 72
Query: 86 IVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
L K + +M I+ N D + PN IR +R + ++ ++ E + +R
Sbjct: 73 ----LMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRK 128
Query: 145 CLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAEL 202
CL+ YVRK A + V ++ ++ L+ D +D+ L+++++P+ NA L+E+
Sbjct: 129 CLKDEDPYVRKTAAVCVAKLHDINAQLVEDQ-GFLDTLKDLISDSNPMVVANAVAALSEI 187
Query: 203 -DREAALNYLQDNLTSIENLDALLQ-----------NAFISFIRKDAIKTPGLVSQYVEL 250
+ + N L N SI L L + +++ KD + + +
Sbjct: 188 AESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPR 247
Query: 251 LQ---DLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEK 307
L +V + +M + L +L +A L+ L + E + ++ V L
Sbjct: 248 LSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPE--LQYVALRN 305
Query: 308 INEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQS 367
IN I +K P L+ + + V + V+ + LDI + L + N+ V+ L KE +
Sbjct: 306 INLIVQKRPEILKH-EMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAEL-KEYAT 363
Query: 368 TADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQV 427
D +++ + +++I + AI+ + + VS LLD I + + I K +
Sbjct: 364 EVD------VDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIKDI 417
Query: 428 IERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+YP ++ TL E L + +A +W++GE+A+
Sbjct: 418 FRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAE 457
>Hs22027653 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 942
Score = 109 bits (272), Expect = 2e-23
Identities = 107/460 (23%), Positives = 205/460 (44%), Gaps = 38/460 (8%)
Query: 28 FQKALEKGSDTE--KIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWE 85
F+ E SD + K +K+++ +M G + L ++ M + N +LKKL+Y Y
Sbjct: 16 FELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNLELKKLVYLY-- 72
Query: 86 IVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
L K + +M I+ N D + PN IR +R + ++ ++ E + +R
Sbjct: 73 ----LMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRK 128
Query: 145 CLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAEL 202
CL+ YVRK A + V ++ ++ L+ D +D+ L+++++P+ NA L+E+
Sbjct: 129 CLKDEDPYVRKTAAVCVAKLHDINAQLVEDQ-GFLDTLKDLISDSNPMVVANAVAALSEI 187
Query: 203 -DREAALNYLQDNLTSIENLDALLQ-----------NAFISFIRKDAIKTPGLVSQYVEL 250
+ + N L N SI L L + +++ KD + + +
Sbjct: 188 AESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPR 247
Query: 251 LQ---DLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEK 307
L +V + +M + L +L +A L+ L + E + ++ V L
Sbjct: 248 LSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPE--LQYVALRN 305
Query: 308 INEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQS 367
IN I +K P L+ + + V + V+ + LDI + L + N+ V+ L KE +
Sbjct: 306 INLIVQKRPEILKH-EMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAEL-KEYAT 363
Query: 368 TADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQV 427
D +++ + +++I + AI+ + + VS LLD I + + I K +
Sbjct: 364 EVD------VDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIKDI 417
Query: 428 IERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+YP ++ TL E L + +A +W++GE+A+
Sbjct: 418 FRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAE 457
>Hs22027651 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 949
Score = 109 bits (272), Expect = 2e-23
Identities = 107/460 (23%), Positives = 205/460 (44%), Gaps = 38/460 (8%)
Query: 28 FQKALEKGSDTE--KIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWE 85
F+ E SD + K +K+++ +M G + L ++ M + N +LKKL+Y Y
Sbjct: 16 FELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNLELKKLVYLY-- 72
Query: 86 IVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
L K + +M I+ N D + PN IR +R + ++ ++ E + +R
Sbjct: 73 ----LMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRK 128
Query: 145 CLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAEL 202
CL+ YVRK A + V ++ ++ L+ D +D+ L+++++P+ NA L+E+
Sbjct: 129 CLKDEDPYVRKTAAVCVAKLHDINAQLVEDQ-GFLDTLKDLISDSNPMVVANAVAALSEI 187
Query: 203 -DREAALNYLQDNLTSIENLDALLQ-----------NAFISFIRKDAIKTPGLVSQYVEL 250
+ + N L N SI L L + +++ KD + + +
Sbjct: 188 AESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPR 247
Query: 251 LQ---DLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEK 307
L +V + +M + L +L +A L+ L + E + ++ V L
Sbjct: 248 LSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPE--LQYVALRN 305
Query: 308 INEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQS 367
IN I +K P L+ + + V + V+ + LDI + L + N+ V+ L KE +
Sbjct: 306 INLIVQKRPEILKH-EMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAEL-KEYAT 363
Query: 368 TADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQV 427
D +++ + +++I + AI+ + + VS LLD I + + I K +
Sbjct: 364 EVD------VDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIKDI 417
Query: 428 IERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+YP ++ TL E L + +A +W++GE+A+
Sbjct: 418 FRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAE 457
>7293642 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 921
Score = 106 bits (265), Expect = 2e-22
Identities = 102/460 (22%), Positives = 199/460 (43%), Gaps = 33/460 (7%)
Query: 25 VSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYW 84
+ + + L +K +K+++ +M G + L ++ M + N +LKKL+Y Y
Sbjct: 15 IFELKSELNNDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNLELKKLVYLY- 72
Query: 85 EIVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVR 143
L K + +M I+ N D + N IR +R + ++ ++ E + +R
Sbjct: 73 -----LMNYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLR 127
Query: 144 ACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAE 201
CL+ YVRK A + V +Y +S ++ D +D L+++++P+ NA L+E
Sbjct: 128 KCLKDEDPYVRKTAAVCVAKLYDISATMVEDQ-GFLDQLKDLLSDSNPMVVANAVAALSE 186
Query: 202 LDREAA-------LNYLQDN--LTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQ 252
++ + +N + N LT++ Q + + + K E +
Sbjct: 187 INEASQSGQPLVEMNSVTINKLLTALNECTEWGQVFILDSLANYSPKDEREAQSICERIT 246
Query: 253 DLLVSTRSTDVMYEAAIT---LTVLTNKEAILLTVANKLID--LATKESDNNIKLVVLEK 307
L + V+ + L +L++ T+ KL + S+ ++ V L
Sbjct: 247 PRLAHANAAVVLSAVKVLMKLLEMLSSDSDFCATLTKKLAPPLVTLLSSEPEVQYVALRN 306
Query: 308 INEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQS 367
IN I +K P L+ + + V + V+ + LDI + L N+ V+ L KE +
Sbjct: 307 INLIVQKRPDILKH-EMKVFFVKYNDPIYVKLEKLDIMIRLANQSNIAQVLSEL-KEYAT 364
Query: 368 TADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQV 427
D +++ + +++I + AI+ + VS LLD I + + I K +
Sbjct: 365 EVD------VDFVRKAVRAIGRCAIKVEPSAERCVSTLLDLIQTKVNYVVQEAIVVIKDI 418
Query: 428 IERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+YP I++TL E L + +A +W++GE+A+
Sbjct: 419 FRKYPNKYESIISTLCENLDTLDEPEARASMVWIIGEYAE 458
>Hs4557469 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 937
Score = 105 bits (262), Expect = 3e-22
Identities = 102/461 (22%), Positives = 197/461 (42%), Gaps = 36/461 (7%)
Query: 25 VSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYW 84
+ + + L ++ +K+++ M G + L ++ M + N +LKKL+Y Y
Sbjct: 15 IFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVN-CMQTDNLELKKLVYLY- 72
Query: 85 EIVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVR 143
L K + +M I+ N+ D + PN IR +R + ++ ++ E + +R
Sbjct: 73 -----LMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLR 127
Query: 144 ACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAE 201
CL+ YVRK A + V ++ ++ ++ D +DS L+A+++P+ NA L+E
Sbjct: 128 KCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQ-GFLDSLRDLIADSNPMVVANAVAALSE 186
Query: 202 LDREAALNYLQD--------NLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQD 253
+ + L D LT++ Q + + K E +
Sbjct: 187 ISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTP 246
Query: 254 LLVSTRSTDVMYEAAITLTVL-------TNKEAILLTVANKLIDLATKESDNNIKLVVLE 306
L S V+ + + L +L +A L+ L + E + ++ V L
Sbjct: 247 RLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPE--VQYVALR 304
Query: 307 KINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQ 366
IN I +K P L+ + + V + V+ + LDI + L + N+ V+ L KE
Sbjct: 305 NINLIVQKRPEILKQ-EIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAEL-KEYA 362
Query: 367 STADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQ 426
+ D +++ + +++I + AI+ + + VS LLD I + + I +
Sbjct: 363 TEVD------VDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRD 416
Query: 427 VIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+ +YP I+ TL E L + A +W++GE+A+
Sbjct: 417 IFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAE 457
>CE24628 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 827
Score = 103 bits (258), Expect = 1e-21
Identities = 98/464 (21%), Positives = 204/464 (43%), Gaps = 45/464 (9%)
Query: 25 VSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYW 84
+ + + L +K +K+++ +M G + L ++ M + N +LKKL+Y Y
Sbjct: 15 IFELKNELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNVELKKLVYLY- 72
Query: 85 EIVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVR 143
L K + ++ I+ N D + PN IR +R + ++ ++ E + +R
Sbjct: 73 -----LMNYAKSQPDLAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVEKITEYLCDPLR 127
Query: 144 ACLEYRHAYVRKYAILAVLSIYKVSDHLIPDA--CEVIDSFLVAETDPICKRNAFLGLAE 201
C++ YVRK A + V ++ ++ L+ + E+++ L+++ +P+ NA L E
Sbjct: 128 RCMKDEDPYVRKTAAVCVAKLHDMNPALVKEQGFVELLND-LLSDANPMVVANAVAALTE 186
Query: 202 LDREAALNYLQDN-----LTSIENL----DALLQNAFISFIRKDAIKTPGLVSQY----- 247
++ + + + LT++ + +A + +D +T + +
Sbjct: 187 MNEQQTVIEVNSQMVNKLLTALNECTEWGQVFILDALAGYTPRDERETQNICERISPRLA 246
Query: 248 ----VELLQDLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLV 303
+L + V + D+M + +T LT K +A ++ L + E + I+ V
Sbjct: 247 HANAAVVLSTVKVLMKLIDMMPADSDFITQLTKK------LAPPMVTLLSAEPE--IQYV 298
Query: 304 VLEKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRK 363
L IN I +K P L+ + + V + V+ + LDI + L N+ V+ L K
Sbjct: 299 ALRNINLIVQKRPDILKQ-EMKVFFVKYNDPIYVKMEKLDIMIRLAQQNNIAQVLSEL-K 356
Query: 364 ELQSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISF 423
E + D +++ + +++I + AI+ S V LL+ I + + +
Sbjct: 357 EYATEVD------VDFVRKSVRAIGRCAIKVEASSERCVQTLLELIQTKVNYVVQEAVVV 410
Query: 424 TKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
K + +YP I++ L E L + +A +W++GE+A+
Sbjct: 411 IKDIFRKYPNRYESIISALCENLDTLDEPEARASMIWIIGEYAE 454
>CE18132 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 896
Score = 88.2 bits (217), Expect = 6e-17
Identities = 104/455 (22%), Positives = 198/455 (42%), Gaps = 37/455 (8%)
Query: 26 SDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWE 85
+D + L+ D K+ MKRI+ + G + +L +++ V +KN +LKKL++ Y
Sbjct: 17 ADLKAMLDSNKDNLKVDAMKRIINLIAKGKDVSELFAAVVKNVA-AKNVELKKLVFVY-- 73
Query: 86 IVPKLDREGKLKQEMILVC-NAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
L R + +Q++ L+ + Q L+ PN+ IRG+ LR LT ++ + M+ +++
Sbjct: 74 ----LVRYAEEQQDLALLSISTFQRALKDPNQLIRGSALRVLTSIRVPMVAPIMLLAIKD 129
Query: 145 CLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDR 204
+ YVRK A A+ +Y + L P + ID FL+A+ + +A E+
Sbjct: 130 AVRDMSPYVRKVAAHAIPKLYSLEPELEPQLVDCID-FLLADRRSLVLGSAVYAFDEICP 188
Query: 205 EAA------LNYLQDNLTSIENLDALLQNAFISFIRKDAIKTP--GLVSQYVELL----Q 252
L L ++ ++ ++ + + P G V LL +
Sbjct: 189 HRLDLLHKHFRALCRGLADVDEWGQIVMINMLTRYARHELADPDRGPPDTDVVLLLNSAR 248
Query: 253 DLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEIN 312
LL S + VM A + L +A L +A L+ L + VVL I I
Sbjct: 249 PLLQSRNCSVVM--AVVQLFYHVAPKAQLSQIARALVRLL--RGPRETQYVVLTNIATIC 304
Query: 313 EKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSS 372
E+NP ++ D L V + V+ L + L++ N V ++ +ELQ+ S
Sbjct: 305 ERNP-TMFDPFLKSFFVRSCDSSLVKKLKLHVLTSLVSEAN----VHIILRELQTYVHMS 359
Query: 373 NDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYP 432
+ +++I + A+R VS ++ L+ I + + + K+++
Sbjct: 360 -----DLASPAVEAIGRCAVRVGAVSDQCMTGLVQLISSSDEKVVCSAVVVIKRLLHASA 414
Query: 433 ELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
L +L+ L+ + + +A+A +W++ H +
Sbjct: 415 PL--NLLSRLMRLMPNMIAAQARACVIWLVATHVE 447
>SPBC947.02 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 683
Score = 87.0 bits (214), Expect = 1e-16
Identities = 100/456 (21%), Positives = 192/456 (41%), Gaps = 36/456 (7%)
Query: 26 SDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWE 85
S+ QK L E+I +KR + M G + L +++ + +++ LKKL+Y Y
Sbjct: 20 SELQKGLVSQYAYERIDAVKRTIAAMTVGKDVSSLFPDVLKN-LATRDITLKKLVYLY-- 76
Query: 86 IVPKLDREGKLKQEM-ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
L K ++ IL N D + N +R +R + ++ +++ + +R
Sbjct: 77 ----LINYAKTHPDLCILAVNTFVKDSEEYNPTLRALAIRTMGCIRVNKIIGYLADPLRK 132
Query: 145 CLEYRHAYVRKYAILAVLSIYKVS-DHLIPDACEVIDSFLVAETDPICKRNAFLGLAEL- 202
L+ H YVRK A + V+ +Y + ++ + LV++ +P+ NA LAE+
Sbjct: 133 ALKDEHPYVRKAAAVCVVKMYDLDREYCASNGFIEQLQALVSDPNPVVVANAVRSLAEIH 192
Query: 203 DREAALNYLQDNLTSIENLDALLQ-----------NAFISFIRKDAIKTPGLVSQYVELL 251
D++ Y T + L L N+ F D + + + V
Sbjct: 193 DQDPEKGYFNVVYTMTDRLMVALSECNEWGRITILNSLARFRTSDIKEAEYVCERVVPQF 252
Query: 252 QDL---LVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKI 308
Q +V + +M + + T + + +A L+ L + +D+ I+ V L I
Sbjct: 253 QHANSGVVLSAVKVIMVHIPLFSSDFT--DFLYKKMAPPLLTLLS--TDSEIQYVALRNI 308
Query: 309 NEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQST 368
N I +K P S+ D+ + L ++ + L I L N++ + LR +
Sbjct: 309 NLILQKRP-SIFDVKTRVFFCKYNDPLYIKMEKLKIITMLACDENINETISELRAYV--- 364
Query: 369 ADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVI 428
++ LE+ + IK + VA++ V ++ +S+ L+ S +V + V+
Sbjct: 365 ----SEVELEFVKQTIKCLGDVALKVPSVINDCISIFLEIYELNISYMVQEVTVVMETVL 420
Query: 429 ERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGE 464
+YP+ +L L + E+ +A W+LGE
Sbjct: 421 RKYPQKIDLLLPYLSRVIEELGDPRARSSMAWILGE 456
>CE12722 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 906
Score = 85.5 bits (210), Expect = 4e-16
Identities = 105/462 (22%), Positives = 203/462 (43%), Gaps = 41/462 (8%)
Query: 26 SDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWE 85
+D + L+ D K+ MKRI+ + G + +L +++ V +KN +LKKL++ Y
Sbjct: 17 ADLKAMLDSNKDNLKVDAMKRIINLIAKGKDVSELFAAVVKNVA-AKNVELKKLVFVY-- 73
Query: 86 IVPKLDREGKLKQEMILVC-NAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
L R + +Q++ L+ + Q L+ PN+ IRG+ LR LT ++ + M+ +++
Sbjct: 74 ----LVRYAEEQQDLALLSISTFQRALKDPNQLIRGSALRVLTSIRVPMVAPIMLLAIKD 129
Query: 145 CLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDR 204
+ YVRK A A+ +Y + L P + ID FL+A+ + +A E+
Sbjct: 130 AVRDMSPYVRKVAAHAIPKLYSLEPELEPQLVDCID-FLLADRRSLVLGSAVYAFDEICP 188
Query: 205 EAA------LNYLQDNLTSIENLDALLQNAFISFIRKDAIKTP--GLVSQYVELL----Q 252
L L ++ ++ ++ + + P G V LL +
Sbjct: 189 HRLDLLHKHFRALCRGLADVDEWGQIVMINMLTRYARHELADPDRGPPDTDVVLLLNSAR 248
Query: 253 DLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEIN 312
LL S + VM A + L +A L +A L+ L + VVL I I
Sbjct: 249 PLLQSRNCSVVM--AVVQLFYHVAPKAQLSQIARALVRLL--RGPRETQYVVLTNIATIC 304
Query: 313 EKNPGSLEDLTLDILRVL---NAQDLDVR----AKALDISLELITSRNVDSVVKLLRKEL 365
E+NP +E+ T I + + + VR + + L ++TS ++ V ++ +EL
Sbjct: 305 ERNP--VEEGTYAISKTMFDPFLKSFFVRSCDSSLVKKLKLHVLTSLVSEANVHIILREL 362
Query: 366 QSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTK 425
Q+ S + +++I + A+R VS ++ L+ I + + + K
Sbjct: 363 QTYVHMS-----DLASPAVEAIGRCAVRVGAVSDQCMTGLVQLISSSDEKVVCSAVVVIK 417
Query: 426 QVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
+++ L +L+ L+ + + +A+A +W++ H +
Sbjct: 418 RLLHASAPL--NLLSRLMRLMPNMIAAQARACVIWLVATHVE 457
>Hs4501975 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1093
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/489 (21%), Positives = 207/489 (41%), Gaps = 64/489 (13%)
Query: 27 DFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWEI 86
D ++ LE D+ K+ MKRI+ + G +L +++ V SKN ++KKL+Y Y
Sbjct: 46 DLKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVA-SKNIEIKKLVYVY--- 101
Query: 87 VPKLDREGKLKQEMILVC-NAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRAC 145
L R + +Q++ L+ + Q L+ PN+ IR + LR L+ ++ ++ M+ +++
Sbjct: 102 ---LVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEA 158
Query: 146 LEYRHAYVRKYAILAVLSIY-----------KVSDHLIPDACEVIDSFLVAETDPICKRN 194
YVRK A A+ +Y +V + L+ D ++ +V + +C
Sbjct: 159 SADLSPYVRKNAAHAIQKLYSLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDR 218
Query: 195 AFLGLAELDREAALNYLQD-----NLTSIENLDALLQNAFISFIRK-------------- 235
+ L + N L D + I L + F+S ++
Sbjct: 219 --IDLIHKNYRKLCNLLVDVEEWGQVVIIHMLTRYARTQFVSPWKEGDELEDNGKNFYES 276
Query: 236 --------DAIKTPGLVSQYVELL----QDLLVSTRSTDVMYEAAITLTVLTNKEAILLT 283
D K P + LL + LL S + VM A + + EA +
Sbjct: 277 DDDQKEKTDKKKKPYTMDPDHRLLIRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGI-- 334
Query: 284 VANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALD 343
++ L+ L S+ ++ +VL+ I ++ + G E L V + ++
Sbjct: 335 ISKSLVRLL--RSNREVQYIVLQNIATMSIQRKGMFEPY-LKSFYVRSTDPTMIKT---- 387
Query: 344 ISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVS 403
+ LE++T+ ++ + L +E Q T S DK ++ I++I + A +EV+ ++
Sbjct: 388 LKLEILTNLANEANISTLLREFQ-TYVKSQDK--QFAAATIQTIGRCATNILEVTDTCLN 444
Query: 404 LLLDFIGNLSSESANDVISFTKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLG 463
L+ + N + + K++++ P EI+ + + L + A LW++G
Sbjct: 445 GLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARASILWLIG 504
Query: 464 EHAQSEAEI 472
E+ + +I
Sbjct: 505 ENCERVPKI 513
>Hs4758760 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1081
Score = 80.9 bits (198), Expect = 9e-15
Identities = 101/516 (19%), Positives = 206/516 (39%), Gaps = 67/516 (12%)
Query: 2 TVGVEQPAYTLVYDPNPNGVTYTV----SDFQKALEKGSDTEKIATMKRILVTMLDGNPL 57
+ G +P Y +DP G+ + D ++ L+ D+ K+ MKRI+ + G
Sbjct: 14 SAGPGEPEYG--HDPASGGIFSSDYKRHDDLKEMLDTNKDSLKLEAMKRIVAMIARGKNA 71
Query: 58 PDLLMHIIRFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVC-NAIQHDLQHPNE 116
DL +++ V KN ++KKL+Y Y L R + +Q++ L+ + Q L+ PN+
Sbjct: 72 SDLFPAVVKNVA-CKNIEVKKLVYVY------LVRYAEEQQDLALLSISTFQRGLKDPNQ 124
Query: 117 YIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIPDAC 176
IR + LR L+ ++ ++ M+ +++ YVRK A A+ +Y +
Sbjct: 125 LIRASALRVLSSIRVPIIVPIMMLAIKEAASDMSPYVRKTAAHAIPKLYSLDSDQKDQLI 184
Query: 177 EVIDSFLVAET-----------DPICKR-------------NAFLGLAELDREAALNYL- 211
EVI+ L +T + +C N + + E + ++ L
Sbjct: 185 EVIEKLLADKTTLVAGSVVMAFEEVCPERIDLIHKNYRKLCNLLIDVEEWGQVVIISMLT 244
Query: 212 ----QDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVSTRSTDVMYEA 267
L+ +N L +NA +F + + G S+ D +
Sbjct: 245 RYARTQFLSPTQNESLLEENAEKAFYGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRL 304
Query: 268 AITLT---VLTNKEAILLTVANKLIDL-------------ATKESDNNIKLVVLEKINEI 311
+ T + + A+++ VA L A S + ++ VVL+ + +
Sbjct: 305 LLRNTKPLLQSRSAAVVMAVAQLYFHLGPRRKWRHRQGAGALLRSHSEVQYVVLQNVATM 364
Query: 312 NEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADS 371
+ K G E L + + ++ L++ L N+ +V++ + ++S
Sbjct: 365 SIKRRGMFEPY-LKSFYIRSTDPTQIKILKLEVLTNLANETNIPTVLREFQTYIRSM--- 420
Query: 372 SNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERY 431
DK ++ I++I + A V ++ L+ + N + + K++++
Sbjct: 421 --DK--DFVAATIQAIGRCATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQ 476
Query: 432 PELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
P EI+ L + ++ A LW++GE+ +
Sbjct: 477 PAQHGEIIKHLAKLTDNIQVPMARASILWLIGEYCE 512
>Hs18596139 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 863
Score = 78.6 bits (192), Expect = 4e-14
Identities = 92/432 (21%), Positives = 182/432 (41%), Gaps = 35/432 (8%)
Query: 25 VSDFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYW 84
+ + + L ++ +K+++ + G + + I+ M + N +LKKL+Y Y
Sbjct: 15 IFELKAELSNEKKEKRKEAVKKVIAVITVGKDVSSVFPDIVN-CMQTDNLKLKKLVYLYL 73
Query: 85 EIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRA 144
++ I+ N+ D + PN IR +R + + ++ E + +
Sbjct: 74 -----MNYANSQPDMAIIAVNSFVKDCEDPNLLIRALAVRTMGCIWVDKITEYLSEPLLK 128
Query: 145 CLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAEL 202
CLE YVRK A + V ++ ++ ++ D +DS L+A+++P+ NA L+E+
Sbjct: 129 CLEDEDPYVRKTAAVCVAKLHDINAQMVEDQ-GFLDSLWGLIADSNPMVVANAVAALSEI 187
Query: 203 -DREAALNYLQDNLTSIENLDALL----QNAFISFIRKDAIKTPGLVSQYVELLQDLLVS 257
+ N L N I L L + A S I T ++ + L+ L
Sbjct: 188 SESHPNSNLLNLNTQYINKLRTALNKCTEGARFSCWTACLITTLKMIGR----LRASLSH 243
Query: 258 TRSTDVMYEAAITLTVL-------TNKEAILLTVANKLIDLATKESDNNIKLVVLEKINE 310
S V+ + + L +L +A L+ L + ES+ + V L IN
Sbjct: 244 ANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLMSGESE--VHYVSLRNINL 301
Query: 311 INEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTAD 370
I +K P L+ + + V + V+ + LDI + L + N+ V+ L+ +
Sbjct: 302 IVQKRPEILKQ-EIKVFFVKYNDPIYVKLEKLDIRIHLASQANIAQVLAELK-------E 353
Query: 371 SSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIER 430
+ + +++ + + + + AI+ + + + VS LLD I + +VI + + +
Sbjct: 354 YATEVNVDFVRKAVWATGRCAIKVEQSAEHCVSTLLDLIKTKVNYVVQEVIVVIRDIFRK 413
Query: 431 YPELRSEILTTL 442
Y I+ TL
Sbjct: 414 YSNKYESIIATL 425
>SPCP1E11.06 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 865
Score = 76.6 bits (187), Expect = 2e-13
Identities = 86/398 (21%), Positives = 161/398 (39%), Gaps = 36/398 (9%)
Query: 97 KQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKY 156
++ + L+ N++Q+DL+ +++I G L + EL + + H Y+ K
Sbjct: 125 QEVLTLLTNSLQNDLKSRDKFIVGLALSAFGNVAGPELARDLSNDIAELCSNHHNYISKK 184
Query: 157 AILAVLSIYKVSDHLIPDACEVIDSFLVAETDPI-----------CKRNAFLGLAELDRE 205
A+L L + + L E D L +++ + CK N L ++ + +
Sbjct: 185 AVLCALRVIQKEPDLESLYIEKTDELLHSKSHGVLMAALAFAISACKINPSL-ISRFESQ 243
Query: 206 A-----ALNYLQDNLTSIEN-----LDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLL 255
A + L + S E+ D LQ + F+ P + + +LL +
Sbjct: 244 ADDLIYRIRQLSTSTYSSEHNIGNISDPFLQVKILQFLSILGQNNPKIYDKMSDLLAQVC 303
Query: 256 VSTRST-----DVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINE 310
+T S+ ++Y+A T+ L N ++ L + ++ DNN + V L +
Sbjct: 304 TNTDSSRNAGNAILYQAVRTILDL-NSDSSLRVLGVNILAKFLGNRDNNTRYVALNMLKL 362
Query: 311 INEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTAD 370
+ +++ IL LN D ++++AL++S L+ NV +V+ L L + +D
Sbjct: 363 VVNSEENAVQRHRSTILACLNDVDSSIQSRALELSTFLVNEANVRFMVRELLSFLDNVSD 422
Query: 371 SSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIER 430
T +Y I +V F LL + + + +S ++I
Sbjct: 423 ELRGSTAQY-------ITEVTNAFAPNKRWHFDTLLRVFKSAGNFVSESTLSTFLRLIAS 475
Query: 431 YPELRSEILTTLIETLHEVKSAKAYR-GALWVLGEHAQ 467
PEL + L L E S +A A WV+GE+ Q
Sbjct: 476 APELHEYAVVKLYAALKEDVSQEALTLSAFWVIGEYGQ 513
>Hs20127438 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 1153
Score = 76.3 bits (186), Expect = 2e-13
Identities = 88/403 (21%), Positives = 176/403 (42%), Gaps = 36/403 (8%)
Query: 100 MILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAIL 159
++L N I+ DL P++Y G L L+ +L + + + + Y+RK A+L
Sbjct: 109 IMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVL 168
Query: 160 AVLSIY-KVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDREAALNYLQDNLTSI 218
+ ++ K + L P + + + + DP + A + EL R NYL
Sbjct: 169 IMYKVFLKYPESLRPAFPRLKEK--LEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFF 226
Query: 219 ENLDALLQN-AFISFIRKDAIKTP---GLVSQYVELLQDLLVSTRSTDVMYEAAITLTV- 273
+ + + N I I+ TP L + +E L +L+ ST + ++YE T+
Sbjct: 227 KLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAV 286
Query: 274 -------LTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDI 326
+ N A + KL + ++SD N+K + L +++I + +P S++ I
Sbjct: 287 LISLSSGMPNHSASIQLCVQKL-RILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLI 345
Query: 327 LRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKS 386
L+ L+ +D +R +ALD+ +++ +N+ +V K+L + D + T YR L+
Sbjct: 346 LQCLDDKDESIRLRALDLLYGMVSKKNLMEIV----KKLMTHVDKAEGTT--YRDELLTK 399
Query: 387 INKVA----IRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPELRS---EIL 439
I + ++I +S+L++ + + + + V R +R +
Sbjct: 400 IIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQM 459
Query: 440 TTLIETLHEVKSAKAYRG-------ALWVLGEHAQSEAEIQNT 475
+ L+++ H + S+ G A W+ GE ++ E +T
Sbjct: 460 SALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHT 502
>SPBC2G2.06c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 677
Score = 73.6 bits (179), Expect = 1e-12
Identities = 95/455 (20%), Positives = 186/455 (40%), Gaps = 47/455 (10%)
Query: 36 SDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWEIVPKLDREGK 95
S ++I+ +K+ + + G + L +I M S N +LKKL Y Y +I + + +
Sbjct: 27 SANKRISALKKAIAGISYGYDMSSLFPSVISS-MESNNLELKKLCYLYLKIYASV-KPTE 84
Query: 96 LKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRK 155
K+ + L+ N D+ N IR LR LT + + + L+ YVRK
Sbjct: 85 AKRAVKLILN----DIYSSNPMIRSLALRTLTSVNIKNFWVAAMDPIVRLLDDTDPYVRK 140
Query: 156 YAILAVLSIYKVSDHLIPDACEVIDSF--LVAETDPICKRNAFLGLAEL----------- 202
A + + +Y ++ ++ +ID ++++ + N+ L +
Sbjct: 141 TAAIGIAKLYSYDKKMV-ESSGLIDHLKEMLSDESSVVVANSLAALMNIVNSSTGFKLTF 199
Query: 203 DREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVSTRSTD 262
RE + ++ E L + +A I ++ + PG + E + L +
Sbjct: 200 SREISNKLVKSLTDCSEWLQVAILDALIFYVPQK----PGEAESFAERISPWLQHGNAAV 255
Query: 263 VMYEAAITLTVLTN--------KEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEK 314
M + L LTN KE + T + LA K S + V+L I I E+
Sbjct: 256 CMGAVKVIL-YLTNYMKDDNRVKEYFMKTQPPLVTLLARKSSAT--QYVILRNIQIILEQ 312
Query: 315 NPGSLEDLTLDI-LRVLNAQD-LDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSS 372
P E DI N D + V+ + LDI ++ N+D + L + +
Sbjct: 313 CP---EMFANDIHFFYCNFDDPIYVKLEKLDILTKIADIHNLDQI-------LPEFVEYA 362
Query: 373 NDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYP 432
++ +E + +K I +AI+ E ++ + L++ + + + + + ++ +YP
Sbjct: 363 SEIDVELVRKSVKCIGYLAIKIEERKNDCIDSLIELMNTKVTYVIQEAVIVIRDILRKYP 422
Query: 433 ELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQ 467
++ L E L + A +W+LG++A+
Sbjct: 423 GSYKSLVPILYENLDSLDEPDAKSAVIWILGQYAE 457
>CE24044 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 1251
Score = 71.6 bits (174), Expect = 5e-12
Identities = 87/397 (21%), Positives = 171/397 (42%), Gaps = 39/397 (9%)
Query: 100 MILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAIL 159
++L N I+ D+ N Y G L L+ +L + V L Y RK A+L
Sbjct: 109 LMLTTNLIRKDVNSSNMYESGIALGGLSCFVTPDLARDLAADVVNLLSCSRNYTRKRAVL 168
Query: 160 AVLSIY-KVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDREAALNYLQ------ 212
+ I+ K D L P + + + + DP + +A + EL R+ NYL
Sbjct: 169 LLYKIFLKYPDALRPTFPRLKEK--LEDPDPGVQSSAVNVICELARKNPKNYLTLAPVFF 226
Query: 213 DNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVSTRSTDVMYEAAIT-L 271
+T+ N L++ I P L + +E L +L+ ST + ++YE T +
Sbjct: 227 KLMTTSSNNWMLIK--IIKLFGALVPLEPRLGKKLLEPLTNLINSTSAMSLLYECINTVI 284
Query: 272 TVLTNKEA-----ILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDI 326
VL + A + + + + + ++SD N+K + L + +I + +P +++ +
Sbjct: 285 AVLISISAGGDHTASIQLCVQKLGVLIEDSDQNLKYLGLLAMGKILKTHPKAVQAHKDIV 344
Query: 327 LRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKS 386
LR L+ +D +R ++LD+ +++ +N+ +VK L + +++ S YR L+
Sbjct: 345 LRCLDDKDESIRIRSLDLLYGMVSKKNIVEIVKKLMEHVEAAEGS------HYRDELLSR 398
Query: 387 INKVA----IRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPELRS---EIL 439
I + ++I +S+L++ +E + + V R +R +
Sbjct: 399 IIGICSWSNYQYITNFEWYISVLVELTKVEGTEHGAKIAEQIQDVTVRVESIRHFSVSQM 458
Query: 440 TTLIETLHEVKSAKAYR---------GALWVLGEHAQ 467
L+E H + + A + A W+ GE++Q
Sbjct: 459 ALLVENAHVLLAGSAQQRSNMCEVLLAAAWICGEYSQ 495
>7292917 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 627
Score = 69.3 bits (168), Expect = 3e-11
Identities = 84/396 (21%), Positives = 165/396 (41%), Gaps = 24/396 (6%)
Query: 100 MILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAIL 159
++L N I+ DL N+Y G L L+ +L + + + Y+R A+L
Sbjct: 110 LMLTTNMIRKDLNSQNQYDAGVALSGLSCFISPDLSRDLANDIMTLMSSTKPYLRMKAVL 169
Query: 160 AVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDREAALNYLQDNLTSIE 219
+ ++ + A + L + DP + A + EL R+ NYL +
Sbjct: 170 MMYKVFLRYPEALRPAFPKLKEKL-EDPDPGVQSAAVNVICELARKNPKNYLPLAPIFFK 228
Query: 220 NLDALLQN-AFISFIRKDAIKTP---GLVSQYVELLQDLLVSTRSTDVMYEAAITLTV-- 273
+ N I I+ TP L + +E L +L+ ST + ++YE T+
Sbjct: 229 LMTTSTNNWMLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECINTVIAVL 288
Query: 274 ------LTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDIL 327
+ N A + KL + ++SD N+K + L +++I + +P S++ IL
Sbjct: 289 ISISSGMPNHSASIQLCVQKL-RILIEDSDQNLKYLGLLAMSKILKTHPKSVQAHKDLIL 347
Query: 328 RVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKSI 387
L+ +D +R +ALD+ +++ +N+ +VK L ++ S+ L Y+ +I+
Sbjct: 348 ACLDDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEGSAYRDELLYK--VIEIC 405
Query: 388 NKVAIRFIEVSSNVVSLLLDFI--------GNLSSESANDVISFTKQVIERYPELRSEIL 439
+ + ++ +++L++ I G L +E DV V + + +L
Sbjct: 406 AQSSYLYVTNFEWYLTVLVELIQLEAGSRHGRLIAEQLLDVAIRVPVVRQFAVNEMTNLL 465
Query: 440 TTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNT 475
T + + A W++GE A + + T
Sbjct: 466 DTFTVSAQSNSMYEVLYAAAWIVGEFAGELEDAEKT 501
>Hs4503843 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 785
Score = 65.1 bits (157), Expect = 5e-10
Identities = 86/398 (21%), Positives = 162/398 (40%), Gaps = 48/398 (12%)
Query: 101 ILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILA 160
+L+ N+I++DL + ++G L L+ + AE+ + P V L YVRK AIL
Sbjct: 102 LLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILT 161
Query: 161 VLSIYKVSDHLIPDACEVIDSFLVAETDPICKRN--AFLGLAELDRE------AALNYLQ 212
+ H+I E+ FL + +R+ LG L E AAL + +
Sbjct: 162 AV-------HMIRKVPELSSVFLPPCAQLLHERHHGILLGTITLITELCERSPAALRHFR 214
Query: 213 DNLTSIEN-LDALLQNAFISFIRKDAIKTPGLVSQYVELLQ--------------DLLVS 257
+ + + L L+ + + + P L Q + LL+ DLL
Sbjct: 215 KVVPQLVHILRTLVTMGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQ 274
Query: 258 -TRSTD--------VMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKI 308
+TD V++E +T+ + + + + N ++ SD NI+ V L +
Sbjct: 275 VATNTDTSRNAGNAVLFETVLTIMDIRSAAGLRVLAVN-ILGRFLLNSDRNIRYVALTSL 333
Query: 309 NEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQST 368
+ + + +++ ++ L D + +AL++SL L+ S NV ++++ L+ L+S
Sbjct: 334 LRLVQSDHSAVQRHRPTVVECLRETDASLSRRALELSLALVNSSNVRAMMQELQAFLESC 393
Query: 369 ADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVI 428
+ R I A RF + +L + + +D ++ Q+I
Sbjct: 394 PP-------DLRADCASGILLAAERFAPTKRWHIDTILHVLTTAGTHVRDDAVANLTQLI 446
Query: 429 ERYPELRSEILTTLIETLHE-VKSAKAYRGALWVLGEH 465
EL + + L L E + + A W +GE+
Sbjct: 447 GGAQELHAYSVRRLYNALAEDISQQPLVQVAAWCIGEY 484
>7290497 [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 1160
Score = 64.7 bits (156), Expect = 7e-10
Identities = 110/562 (19%), Positives = 223/562 (39%), Gaps = 107/562 (19%)
Query: 27 DFQKALEKGSDTEKIATMKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWEI 86
D ++ L+ D K+ MKRI+ + G DL +++ V+ SKN ++KKL+Y Y
Sbjct: 47 DLKQMLDSNKDGLKLEAMKRIIGMIARGRDASDLFPAVVKNVV-SKNIEVKKLVYVY--- 102
Query: 87 VPKLDREGKLKQEMILVC-NAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRAC 145
L R + +Q++ L+ + Q L+ PN+ IR + LR L+ ++ + ++ ++ ++R
Sbjct: 103 ---LVRYAEEQQDLALLSISTFQRALKDPNQLIRASALRVLSSIRVSMIVPIVMLAIRDS 159
Query: 146 LEYRHAYVRKYAILAVLSIYK-----------VSDHLIPDACEVIDSFLVAETDPICKRN 194
YVRK A A+ +Y V + L+ D ++ V D +C
Sbjct: 160 AADLSPYVRKTAAHAIPKLYSLDADQKDELVMVIEKLLSDRTTLVVGSAVMAFDEVCPER 219
Query: 195 AFLGLAELDREAALNYLQD-----NLTSIENLDALLQNAFI-------SFIRKDAIKTPG 242
+ L + N+L D + I L + F+ + +TP
Sbjct: 220 --VDLIHKNYRKLCNFLLDVDEWGQVIIINMLTRYARTQFVDPNADDEDLVNDGLGETPV 277
Query: 243 LVSQYVELLQDLLVSTRSTDVMYEAAITLTVLTNK---------------EAILLTVANK 287
Y E S+ S D + + NK + + V ++
Sbjct: 278 SERFYDESSHS---SSHSDDGSSDDEKNKSSTNNKNNGGGNGSRTPSSPSNSYHIDVDHR 334
Query: 288 LIDLATK---ESDN-NIKLVVLEKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALD 343
L+ TK +S N ++ + V + + + KN L + ++R+L + +V++ L+
Sbjct: 335 LLLRQTKPLLQSRNASVVMAVAQLYHHVAPKNEVQL--IAKALIRLLRSHK-EVQSVVLN 391
Query: 344 ISLELITSRNV---------------DSVVKLLRKELQSTADSSNDKTLEYRQL------ 382
+ T R + +KLL+ ++ + S+ +L R+
Sbjct: 392 CIASMSTKRKAIFEPHLKSFFVRTSDPTHIKLLKLDILTNLASAGSISLILREFQTYISS 451
Query: 383 --------LIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPEL 434
I++I + A EV+ +S L+ + N + + K++++
Sbjct: 452 SDRSFVAATIQAIGRCASSIKEVTETCLSGLVHLLSNHDEHVVAESVVVIKRLLQTKAAE 511
Query: 435 RSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGEVPIVQSE-L 493
EI+T + + + + A +W++GE+ + +VP++ + L
Sbjct: 512 HFEIITQMAKLIDYINVPAARAAIIWLIGEYNE-----------------KVPLIAPDVL 554
Query: 494 RRVQND--DEDDTEKAPIVSTG 513
R++ DE D K +++ G
Sbjct: 555 RKMAKSFVDEQDVVKLQVLNLG 576
>At1g23900 [U] KOG1062 Vesicle coat complex AP-1 gamma subunit
Length = 876
Score = 64.3 bits (155), Expect = 9e-10
Identities = 85/397 (21%), Positives = 162/397 (40%), Gaps = 37/397 (9%)
Query: 97 KQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKY 156
++ ++LV N+++ DL H N+Y+ G L L + AE+ + P V +++R +RK
Sbjct: 100 QEVLMLVTNSLKQDLNHSNQYVVGLALCALGNICSAEMARDLAPEVERLIQFRDPNIRKK 159
Query: 157 AILAVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFL--GLAELDREAALNYLQDN 214
A L I + L + S L + + L L ++ E AL Y +
Sbjct: 160 AALCSTRIIRKVPDLAENFVNAAASLLKEKHHGVLITGVQLCYELCTINDE-ALEYFRTK 218
Query: 215 LTS--IENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQ----------DLL------V 256
T I+ L + +A+ I P L + + LL+ DL+ V
Sbjct: 219 CTEGLIKTLRDITNSAYQPEYDVAGITDPFLHIRLLRLLRVLGQGDADASDLMTDILAQV 278
Query: 257 STRSTD-------VMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKIN 309
+T++ V+YE T+ + + ++ + N ++ DNNI+ V L +
Sbjct: 279 ATKTESNKNAGNAVLYECVETIMAIEDTNSLRVLAIN-ILGRFLSNRDNNIRYVALNMLM 337
Query: 310 EINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTA 369
+ + +++ + IL + D +R +AL++ L+ NV L KEL
Sbjct: 338 KAITFDDQAVQRHRVTILECVKDPDASIRKRALELVTLLVNENNVTQ----LTKELIDYL 393
Query: 370 DSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIE 429
+ S++ ++++ L I + +F + +L + +DV VI
Sbjct: 394 EISDE---DFKEDLSAKICFIVEKFSPEKLWYIDQMLKVLCEAGKFVKDDVWHALIVVIS 450
Query: 430 RYPELRSEILTTLIET-LHEVKSAKAYRGALWVLGEH 465
EL + L ++ L + R A+W +GE+
Sbjct: 451 NASELHGYTVRALYKSVLTYSEQETLVRVAVWCIGEY 487
>SPAC144.06 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 834
Score = 61.2 bits (147), Expect = 7e-09
Identities = 77/316 (24%), Positives = 131/316 (41%), Gaps = 33/316 (10%)
Query: 100 MILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAIL 159
++L N ++ DL + L+ L + V L + YVRK IL
Sbjct: 98 LMLTTNLLKKDLMSSKVPEITLAIDGLSHFSTLGLARDLYRDVLILLNHSVPYVRKRTIL 157
Query: 160 AV----LSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDREAALNYLQDNL 215
+ L + IP E +D + D A + EL R A NYL+
Sbjct: 158 LLYRLCLQYPEAISACIPKLRERLD-----DPDTSVVNAAVSVICELARRAPKNYLEFAP 212
Query: 216 TSIENLDALLQN-AFISFIRKDAIKTP---GLVSQYVELLQDLLVSTRSTDVMYEAAITL 271
L N I I+ A TP LV + + L D++ +T + ++YE T
Sbjct: 213 DLFHLLTTSSNNWMLIKLIKLFASLTPYEPRLVKKLIPSLTDIIENTHAMSLLYECINT- 271
Query: 272 TVLTNKEAILLTVANKLIDLAT-------KESDNNIKLVVLEKINEINEKNPGSLEDLTL 324
+++ + + +KL L +++D N+K + L + ++ +P SL L
Sbjct: 272 -IVSGNMLVGHSQCDKLASLCASKLRGFFEDTDQNLKYIALLCLRKLANTHP-SLVSAQL 329
Query: 325 DI-LRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLL 383
DI L+ L D +R +ALD+ E++ N+ ++VK L +L ++D S + +
Sbjct: 330 DIILKCLVDTDTSIRLRALDLVNEIVNKENIRTIVKTLMLQLIVSSDESAVEDIR----- 384
Query: 384 IKSINKVAIRFIEVSS 399
N A R IE++S
Sbjct: 385 ----NSTATRIIEMTS 396
>Hs5729742 [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 739
Score = 60.5 bits (145), Expect = 1e-08
Identities = 83/436 (19%), Positives = 174/436 (39%), Gaps = 32/436 (7%)
Query: 44 MKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEM-IL 102
++R++ M G + + M +++ Q KKL+Y Y + LK ++ +L
Sbjct: 33 IQRVIRYMTQGLDMSGVFMEMVKASATVDIVQ-KKLVYLY------MCTYAPLKPDLALL 85
Query: 103 VCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVL 162
N + D PN +RG LR + L+ + E + + L + +YVR+ +L
Sbjct: 86 AINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVVVLGCA 145
Query: 163 SIYKVSDHLIPDACEVIDSF-LVAETDPICKRNAFLGLAELDRE---AALN--YLQDNLT 216
++ + D V + + L+ + DPI N L E+ ++ +N L
Sbjct: 146 KMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVINKPIAHHLLN 205
Query: 217 SIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVSTRSTDVMYEAAITLTVLTN 276
+ LD Q ++F+ + ++ + + LL L S+ S V+ A +L
Sbjct: 206 RMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSS-SPGVVMGATKLFLILAK 264
Query: 277 -----KEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDILRVLN 331
+ +L+ V L+ + ES + V L + +I PG
Sbjct: 265 MFPHVQTDVLVRVKGPLLAACSSES-RELCFVALCHVRQILHSLPGHFSSHYKKFF-CSY 322
Query: 332 AQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKSINKVA 391
++ ++ + +++ EL+ NV V++ LR D + ++ Q I +I +A
Sbjct: 323 SEPHYIKLQKVEVLCELVNDENVQQVLEELR-------GYCTDVSADFAQAAIFAIGGIA 375
Query: 392 IRFIEVSSNVVSLLLDFIGNLSSESANDVISFTKQVIERYPELRSEILTTLIETLHEVKS 451
+ + V +L + +G V+ + ++ P+ + L ++
Sbjct: 376 RTY---TDQCVQILTELLGLRQEHITTVVVQTFRDLVWLCPQCTEAVCQALPGCEENIQD 432
Query: 452 AKAYRGALWVLGEHAQ 467
++ + +W+LG H +
Sbjct: 433 SEGKQALIWLLGVHGE 448
>YKL135c [U] KOG1061 Vesicle coat complex AP-1/AP-2/AP-4 beta subunit
Length = 726
Score = 57.4 bits (137), Expect = 1e-07
Identities = 89/453 (19%), Positives = 198/453 (43%), Gaps = 35/453 (7%)
Query: 44 MKRILVTMLDGNPLPDLLMHIIRFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMILV 103
+K+ + M G + L +++ + +Q KKL+Y Y ++ + +L IL
Sbjct: 47 IKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQ-KKLVYLY--VMNYAETHPEL---CILA 100
Query: 104 CNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAVLS 163
N D Q PN IR +R ++ ++ ++LE + +R L +AYVRK A++ V
Sbjct: 101 VNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTAVICVAK 160
Query: 164 IYKVSDHLIPDACEVIDSF-LVAETDPICKRNAFLGLAE-----LDREAALNYLQDNLTS 217
+++++ L + V D + +++P+ NA L E +D + +Q +++
Sbjct: 161 LFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHVSQ 220
Query: 218 I--------ENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVS-TRSTDVMYEAA 268
E ++ + KD+++ ++ + LQ + + +T +
Sbjct: 221 FLLALNECTEWARIIILGTLSEYSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKVIVRN 280
Query: 269 ITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDILR 328
+ ++ I+ +++ + L + + ++ V L+ I I EK P L L I
Sbjct: 281 LPQIEYSSNSLIMKRLSSAFVSLMSTPPE--MQYVALKNIRIILEKYP-ELLTKELRIFY 337
Query: 329 VLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKSIN 388
V L V+ + +DI + L+ N+ LL EL+ A + E+ I++++
Sbjct: 338 VKFNDPLYVKLEKIDILVRLVDPSNLKQCT-LLLTELKEYA---MEYEPEFVSRAIQALS 393
Query: 389 KVAIRFIEVS--SNVVSLLLDFIGNLSSESANDVISFTKQV-----IERYPELRSEILTT 441
++ I++ + S S V+ +LL+ + + + IS + ++ + + T
Sbjct: 394 QLGIKYAQESFVSKVLDILLELLERQDTIKDDCCISLCDLLRHCPGNDKMAKQVCAVFNT 453
Query: 442 LIETLHEVKSAKAYRGALWVLGEHAQSEAEIQN 474
++S A +W+LG+H + +++++
Sbjct: 454 WSNPEVLLQSDIAKCNYVWLLGQHPNNFSDLES 486
>YNL287w [U] KOG1078 Vesicle coat complex COPI gamma subunit
Length = 935
Score = 56.2 bits (134), Expect = 2e-07
Identities = 146/854 (17%), Positives = 325/854 (37%), Gaps = 125/854 (14%)
Query: 44 MKRILVTMLDGNPLPD----LLMHIIRFVMPSKNKQLKKLLYFYWEIVPKLDREGKLKQE 99
+ R+L + G P L I + +N L++ +Y + + ++
Sbjct: 45 ISRLLRLLAQGETFPQNEATALFFSISKLFQHQNDPLRQAVYL------AIKELSGISED 98
Query: 100 MILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAIL 159
+++ ++I D+Q+ ++ I+ + +R LT + + +++ + RH + A+
Sbjct: 99 VLMATSSIMKDVQNGSDLIKPDAIRSLTYVLDESTAFSAERLLKSAVVSRHPSISSAALC 158
Query: 160 AVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAF---------------------LG 198
S HL+P + I F + + F LG
Sbjct: 159 -------TSYHLLPISEVTIRRFTNETQEAVLDLKQFPNQHGNSEYYPNSTYISQYHALG 211
Query: 199 ----LAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDL 254
L + D+ A L ++ + + L + + + + P L SQ+ LL D
Sbjct: 212 LLYQLKKTDKMALLKLVRHFSENNSMKNQLAKVELVKIVNDLIYRDPQLFSQFRPLLSDW 271
Query: 255 LVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDN-------NIKLVVLEK 307
L S + V E A +T + + L VA +L A + + + L
Sbjct: 272 L-SNKFESVQLETAKLITSFATRNSRL--VAPELYAAAISALQSLLTVPRVSSRFAALRI 328
Query: 308 INEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQS 367
+N I+ +P + ++ ++N + ++ A+ L+ TS+N+ S++ + +
Sbjct: 329 LNRISMVSPEKIVVCNPELESLINDSNRNISTYAITTLLKTGTSKNISSLISTITNFIHD 388
Query: 368 TADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSS--ESANDVISFTK 425
+D +++ ++I ++ +++ F + ++++ L+D + N + N ++
Sbjct: 389 VSD-------DFKIIIIDAVRTLSLNFPQEWKSILNFLIDVLKNSEGGFKFKNSIVEALI 441
Query: 426 QVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGE 485
++ P+ + L L + + + + + L +LG+ S N ++R
Sbjct: 442 DIVSFVPQSKELALENLCDFIEDCEFNEILVRILHLLGKEGPS---APNPSLYVRHIYNR 498
Query: 486 VPIVQSELRRVQNDDEDDTEKAPIVSTGPVVL-PDGTYATESALSVSEKVKSTSNEEKEA 544
V + S +R A +V+ L + ES +S+ +++ + ++E
Sbjct: 499 VVLENSIIR-----------SAAVVALSKFALTKNDPTLYESIISLLKRIANDKDDEVRD 547
Query: 545 RPPLRRFVLNGDFFTASVLANSIVKLVLKFEKISKNTSVTNALKAEGLLILVSIIRLGQS 604
R + ++ V+A ++++ ++ S + +++ + + S
Sbjct: 548 RATIALEFIDSARNKDDVIAQNLIESKYFYDIPSLESKLSSYISSN----TDSFATAFDV 603
Query: 605 NLVEKKIDEDSAERLMTAISVLMDEISTEESQAEKELLSLAFLEATNESYKSRVNVTLKK 664
N V K +++ M AI++ + ++E L + E+ E ++ N
Sbjct: 604 NQVRKFTEDE-----MKAINLKRKQEQIFNQKSETTLDTTPEAESVPEK-RADANSFAGP 657
Query: 665 NAAKRSNYLAKHAEAIDKSIVFRQFKNAGLHNTPVDSIEEDIKLATTGTVSYSKLQANSI 724
N L A D+ + Q K G + ++ +S ++ +A +
Sbjct: 658 NLDDHQEDLLATKYA-DELLSIEQIKPFGQ------------LVNSSRAISLTEPEAEFV 704
Query: 725 TSKLKKIVPLTGFSDPVYAECYITNHQFDVVLDVLLVNQTKDTLKNLHVQFATLGDLKII 784
+K + F D V + ITN D+ LD + V T + ++ L L++
Sbjct: 705 VRGVKHL-----FKDNVVLQFNITNTLTDIALDNVSVVCTPEISDEAELE--ELFTLQVD 757
Query: 785 DHPPS------------TNVIPHGF-HKITITAKVSSADTGVIFGNIIYDGGHGQDSRYV 831
PS ++ GF + +T T K + DT N +DG G Y
Sbjct: 758 RLLPSEEAACYVAFKKLDEIVMEGFLNNLTFTTKEINPDT-----NEPFDGDEGFQDEYE 812
Query: 832 ILNDVHIDTMDYVK 845
I + + ++ DYVK
Sbjct: 813 I-DSIFLNAGDYVK 825
>At1g48760 [U] KOG1059 Vesicle coat complex AP-3 delta subunit
Length = 869
Score = 54.3 bits (129), Expect = 9e-07
Identities = 59/271 (21%), Positives = 124/271 (44%), Gaps = 15/271 (5%)
Query: 100 MILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAIL 159
M+L+ N ++ DL NEY L L+++ +L + P V L ++V+K AI
Sbjct: 109 MLLITNQVRKDLNSANEYEVSLALECLSRIGTHDLARDLTPEVFTLLGSSKSFVKKKAIG 168
Query: 160 AVLSIYKVSDHLIPDACEVIDSFLVAE---TDP---ICKRNAFLGLAELDREAALNYLQD 213
VL +++ DA +V LV +DP F LA D ++ L +
Sbjct: 169 VVLRVFE----KYHDAVKVCFKRLVENLETSDPQILSAVVGVFCELATKDPQSCLPLAPE 224
Query: 214 -NLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLLVSTRSTDVMYEAAITL- 271
+++ + + + K A+ P L + E + + + T + +++E T+
Sbjct: 225 FYKVLVDSRNNWVLIKVLKIFAKLALIEPRLGKKVAEPICEHMRRTVAKSLVFECVRTVV 284
Query: 272 -TVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLEDLTLDILRVL 330
++ N+ A+ L VA I E D N+K + L ++ + K+ ++ + +++ +
Sbjct: 285 SSLSDNEAAVKLAVAK--IREFLVEDDPNLKYLGLNALSIVAPKHLWAVLENKEVVVKAM 342
Query: 331 NAQDLDVRAKALDISLELITSRNVDSVVKLL 361
+ +D +V+ +AL + + ++ NV + ++L
Sbjct: 343 SDEDPNVKLEALHLLMAMVNEDNVSEISRIL 373
>Hs6912320 [U] KOG1078 Vesicle coat complex COPI gamma subunit
Length = 871
Score = 53.5 bits (127), Expect = 2e-06
Identities = 67/413 (16%), Positives = 171/413 (41%), Gaps = 49/413 (11%)
Query: 71 SKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLK 130
S ++ L+++ Y + + +++I+V +++ D+ + RG +R L ++
Sbjct: 79 SNDQTLRRMCYL------TIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRIT 132
Query: 131 EAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIPDACEVIDSFLVAETDPI 190
+ +L+ + ++ + + + V A+++ L + K+S ++ + ++ A +D I
Sbjct: 133 DGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRW--INEAQEAASSDNI 190
Query: 191 CKRNAFLGLAELDREAALNYLQDNLTSIENLDALLQNAFISFIRKDAIKTPGLVSQYVEL 250
+ LG+ L +L+ N D L + ++ K +K+ + +
Sbjct: 191 MVQYHALGV--------LYHLRKN-------DRLAVSKMLNKFTKSGLKSQFAYCMLIRI 235
Query: 251 LQDLLVSTRSTD------------------VMYEAAITLTVLTNKEAILLTVANKLIDLA 292
LL T V+YEAA + L N A L A ++ L
Sbjct: 236 ASRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLF 295
Query: 293 TKESDNNIKLVVLEKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSR 352
++ + +N++ K+P ++ LD+ ++ + + A+ L+ +
Sbjct: 296 CSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSES 355
Query: 353 NVDSVVKLLRKELQSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNL 412
+VD ++K + + +D E++ +++++I+ + ++ S +++ L + + +
Sbjct: 356 SVDRLMKQISSFVSEISD-------EFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDD 408
Query: 413 SS-ESANDVISFTKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGE 464
E ++ ++E PE + L L E + + + L +LG+
Sbjct: 409 GGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGK 461
>Hs11559929 [U] KOG1078 Vesicle coat complex COPI gamma subunit
Length = 874
Score = 52.8 bits (125), Expect = 3e-06
Identities = 70/418 (16%), Positives = 168/418 (39%), Gaps = 46/418 (11%)
Query: 96 LKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRK 155
+ +++I+V +++ D+ + RG +R L ++ ++ +L+ + ++ + + V
Sbjct: 98 IAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSS 157
Query: 156 YAILAVLSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAELDREAALNYLQDNL 215
A+++ L + K S ++ V ++ A +D I + LGL L
Sbjct: 158 SALVSSLHLLKCSFDVVKRW--VNEAQEAASSDNIMVQYHALGL---------------L 200
Query: 216 TSIENLDALLQNAFISFIRKDAIKTPGLVSQYVELLQDLL------------------VS 257
+ D L N IS + + +K+P + + L +
Sbjct: 201 YHVRKNDRLAVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLR 260
Query: 258 TRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPG 317
+ V+YEAA + L A L A ++ L ++ + +N++ K+P
Sbjct: 261 NKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPS 320
Query: 318 SLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVKLLRKELQSTADSSNDKTL 377
++ LD+ ++ + + A+ L+ + ++D ++K + + +D
Sbjct: 321 AVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISD------- 373
Query: 378 EYRQLLIKSINKVAIRFIEVSSNVVSLLLDFIGNLSS-ESANDVISFTKQVIERYPELRS 436
E++ +++++I+ + ++ + +++ L + E ++ +IE E +
Sbjct: 374 EFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIEENSESKE 433
Query: 437 EILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTWKHIRSSIGEVPIVQSELR 494
L+ L E + + + L +LG Q + N K+IR V + E+R
Sbjct: 434 TGLSHLCEFIEDCEFTVLATRILHLLG---QEGPKTTNPSKYIRFIYNRVVLEHEEVR 488
>YGR261c [U] KOG1060 Vesicle coat complex AP-3 beta subunit
Length = 809
Score = 51.6 bits (122), Expect = 6e-06
Identities = 91/473 (19%), Positives = 187/473 (39%), Gaps = 54/473 (11%)
Query: 44 MKRILVTMLDGNPLPDLLMHIIRFV--MPSKNKQLKKLLYFYWEIVPKLDREGKLKQEMI 101
MKRI+ M + D+ ++ V + + + ++K+L++ Y ++ + + L +
Sbjct: 63 MKRIISIMASDDDSIDVQLYFADVVKNITTNDTKVKRLIHLY--LLRFAENDPNLT---L 117
Query: 102 LVCNAIQHDLQHPNEYIRGNTLRFLTKLKEAELLEQMVPSVRACLEYRHAYVRKYAILAV 161
L N++Q L N +R L L+ +K + L ++ +V+ + A VR LA+
Sbjct: 118 LSINSLQKSLSDSNSELRCFALSALSDMKMSSLAPIILHTVKKLVTDPSAMVRGEVALAI 177
Query: 162 LSIYKVSDHLIPDACEVIDSFLVAETDPICKRNAFLGLAEL---DREAALNYLQDNLTSI 218
+ +Y+ + + I L+A+TDP A L E E + + I
Sbjct: 178 IKLYRAGKNDYHEELLDILKELMADTDPKVISCAVLAYKECYADHLELLHGHFRRYCRII 237
Query: 219 ENLDALLQNAFISFIRK-----------------DAIKTPGLVSQYVELLQDLLVSTRST 261
+ LD+ Q+ I + K + ++ L +Y E+
Sbjct: 238 KQLDSWSQSYLIELLIKYCKQYLPKPTVVDKSSEGSPRSCPLPDKYNEIEYPSYEVVNDP 297
Query: 262 DV-MYEAAITLTVLTNKEAILLTVANKLIDLATKESDNNIKLVVLEKINEINEKNPGSLE 320
D+ ++ ++ + ++ ++L+ N L LA+ N K + +N G+ E
Sbjct: 298 DLDLFLQSLNCLIYSSNPTVILSCCNALYQLASPLQMKNTKFIEALVRTVTMTENQGNKE 357
Query: 321 DL--TLDILRVLN---------------AQDLDVRAKALDISLELITSRNVDSVVKLLRK 363
L + L +L+ + + I LI NV + K L+
Sbjct: 358 MLLQAIHFLSILDQTLFLPYTKKFYVFPKDPIVASIWKIQILSTLINESNVKEIFKELKY 417
Query: 364 ELQSTADSSNDKTLEYRQLLIKSINKVAIRFIEVSSNVVSLLLDFI--GNLSSESANDVI 421
+ S N + +KS+++ S+V+ L+D + NLS+ + +
Sbjct: 418 YVASAHFPENVVI-----MAVKSLSRCGQLSTSWESHVMKWLIDHMESHNLSASVLDAYV 472
Query: 422 SFTKQVIERYPELRSEILTTLIE--TLHEVKSAKAYRGALWVLGEHAQSEAEI 472
+ + ++++ P I+ L + T+ + A G +W+ GE A E +I
Sbjct: 473 NVIRMLVQKNPTKHLRIIFKLADLLTVQTSLADNARAGIVWLFGEIASIEFKI 525
>7302058 [U] KOG1078 Vesicle coat complex COPI gamma subunit
Length = 879
Score = 51.6 bits (122), Expect = 6e-06
Identities = 80/436 (18%), Positives = 189/436 (43%), Gaps = 36/436 (8%)
Query: 71 SKNKQLKKLLYFYWEIVPKLDREGKLKQEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLK 130
SK+ L++++Y + + +++I+V +++ D+ + R +R L +
Sbjct: 80 SKDVVLRRMVYL------GIKELSSIAEDVIIVTSSLTKDMTGKEDLYRAAAIRALCSIT 133
Query: 131 EAELLEQMVPSVRACLEYRHAYVRKYAILAVLSIYKVSDHLIP----DACEVIDSFLVAE 186
+ +L+ + ++ C+ ++A V A+++ L + + ++ +A E ++S
Sbjct: 134 DNTMLQAVERYMKQCIVDKNAAVSCAALVSSLRLANTAGDVVKRWANEAQEALNS----- 188
Query: 187 TDPICKRNAFLGLAELDREA---ALNYLQDNLT--SIENLDA--LLQNAFISFIRKDAIK 239
D I + LGL R++ A++ L + LT S+++ A +L I ++ I
Sbjct: 189 -DNIMVQYHALGLLYHIRKSDRLAVSKLVNKLTRGSLKSPYAVCMLIRIACKLIEEEDIP 247
Query: 240 TPGLVSQYVELLQDLLVSTRSTDVMYEAAITLTVLTNKEAILLTVANKLIDLATKESDNN 299
+ L + + + +S V+YEAA + L N +L+ A ++ L
Sbjct: 248 SEELSDSPLFTFIESCLRHKSEMVIYEAAHAIVNLKNTNPRMLSPAFSILQLFCSSPKAT 307
Query: 300 IKLVVLEKINEINEKNPGSLEDLTLDILRVLNAQDLDVRAKALDISLELITSRNVDSVVK 359
++ + +N++ +P ++ LD+ ++ D +++ + +S V+
Sbjct: 308 LRFAAVRTLNKVAMTHPAAVTTCNLDLEGLIT----DSNRSVATLAITTLLKTGAESSVE 363
Query: 360 LLRKELQSTADSSNDKTLEYRQLLIKSINKVAIRFIE---VSSNVVSLLLDFIGNLSSES 416
L K++ + +D E++ +++++I + ++ V N +S +L G L E
Sbjct: 364 RLMKQISTFVAEISD---EFKVVVVQAICALCTKYPRKHTVLMNFLSGMLREEGGL--EY 418
Query: 417 ANDVISFTKQVIERYPELRSEILTTLIETLHEVKSAKAYRGALWVLGEHAQSEAEIQNTW 476
++ +IE + + L+ L E + + + L +LG+ A
Sbjct: 419 KTSIVDTIITIIEENADAKESGLSHLCEFIEDCEHVSLAVRILHLLGKEGPFAATPSKYI 478
Query: 477 KHIRSS-IGEVPIVQS 491
+ I + I E PIV++
Sbjct: 479 RFIYNRVILESPIVRA 494
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,848,711
Number of Sequences: 60738
Number of extensions: 2223623
Number of successful extensions: 7550
Number of sequences better than 1.0e-05: 39
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 7426
Number of HSP's gapped (non-prelim): 59
length of query: 971
length of database: 30,389,216
effective HSP length: 116
effective length of query: 855
effective length of database: 23,343,608
effective search space: 19958784840
effective search space used: 19958784840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)