ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3789 good A KOG3167 RNA processing and modification Box H/ACA snoRNP component, involved in ribosomal RNA pseudouridinylation
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3789 1337026 1336580 -149
(149 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL208w [A] KOG3167 Box H/ACA snoRNP component involved in ribos... 172 1e-43
SPAC1782.10c [A] KOG3167 Box H/ACA snoRNP component involved in ... 134 3e-32
At5g08180 [A] KOG3167 Box H/ACA snoRNP component involved in rib... 102 1e-22
Hs8923444 [A] KOG3167 Box H/ACA snoRNP component involved in rib... 99 3e-21
CE19186 [A] KOG3167 Box H/ACA snoRNP component involved in ribos... 83 1e-16
7294353 [A] KOG3167 Box H/ACA snoRNP component involved in ribos... 77 6e-15
7297543 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A... 69 3e-12
SPAC607.03c [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2... 66 1e-11
Hs4826860 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L... 66 1e-11
At5g20160 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L... 65 3e-11
At4g22380 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L... 65 3e-11
YEL026w [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A... 64 6e-11
At4g12600 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L... 64 6e-11
CE02283 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A... 64 1e-10
ECU07g0460 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/... 60 8e-10
ECU11g0940 [A] KOG3167 Box H/ACA snoRNP component involved in ri... 59 2e-09
Hs22047689_1 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP... 50 1e-06
>YDL208w [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 173
Score = 172 bits (437), Expect = 1e-43
Identities = 90/147 (61%), Positives = 99/147 (67%)
Query: 3 KDKSVSTEDNYEARLPAVLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXRGVKEVVKALRK 62
+ K T DNYEAR+PAVLPFAKP RGVKEVVKALRK
Sbjct: 27 ESKESKTVDNYEARMPAVLPFAKPLASKKLNKKVLKTVKKASKAKNVKRGVKEVVKALRK 86
Query: 63 GDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATKRPTSVVFIVPGS 122
G+KGLVVIAGDI P DVISH+PVLCED SVPYIF+PSKQDLG+AGATKRPTSVVFIVPGS
Sbjct: 87 GEKGLVVIAGDISPADVISHIPVLCEDHSVPYIFIPSKQDLGAAGATKRPTSVVFIVPGS 146
Query: 123 NXXXXXXXXXXXXXXXFDEIVKEVSSL 149
N F+E+VKEV +L
Sbjct: 147 NKKKDGKNKEEEYKESFNEVVKEVQAL 173
>SPAC1782.10c [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 154
Score = 134 bits (338), Expect = 3e-32
Identities = 75/154 (48%), Positives = 92/154 (59%), Gaps = 7/154 (4%)
Query: 1 MAKDK-----SVSTEDNYEARLPAVLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXRGVKE 55
MAKDK S STED Y++ LPA++P AKP RGVKE
Sbjct: 1 MAKDKKDHKHSGSTEDEYDSYLPALMPIAKPLAPKKLNKKMMKTVKKASKQKHILRGVKE 60
Query: 56 VVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATKRPTSV 115
VVKA+RKG+KGLV++AGDI P DVISH+PVLCED +VPY++ SK+ LG A TKRPTS
Sbjct: 61 VVKAVRKGEKGLVILAGDISPMDVISHIPVLCEDNNVPYLYTVSKELLGEASNTKRPTSC 120
Query: 116 VFIVPGSNXXXXXXXXXXXXXXXFDEIVKEVSSL 149
V IVPG ++EI+KEV +L
Sbjct: 121 VMIVPGGK--KKDMSKVEEYKESYEEIIKEVPAL 152
>At5g08180 [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 156
Score = 102 bits (255), Expect = 1e-22
Identities = 55/116 (47%), Positives = 69/116 (59%), Gaps = 2/116 (1%)
Query: 4 DKSVSTEDNYEARLPAVLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXRGVKEVVKALRKG 63
+KS+ E A A P AKP RGVKEVVK++R+G
Sbjct: 8 EKSIQKEKKKYAITLA--PIAKPLAGKKLQKRTFKLIQKAAGKKCLKRGVKEVVKSIRRG 65
Query: 64 DKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATKRPTSVVFIV 119
KGL VIAG+I P DVI+HLP+LCE+ VPY++VPSK+DL AGATKRPT V ++
Sbjct: 66 QKGLCVIAGNISPIDVITHLPILCEEAGVPYVYVPSKEDLAQAGATKRPTCCVLVM 121
>Hs8923444 [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 153
Score = 98.6 bits (244), Expect = 3e-21
Identities = 53/148 (35%), Positives = 78/148 (51%), Gaps = 11/148 (7%)
Query: 2 AKDKSVSTEDNYEARLPAVLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXRGVKEVVKALR 61
A+ ++ S E Y+ L P A+P RGVKEV K +
Sbjct: 13 AQAEACSGERTYQELLVNQNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVN 72
Query: 62 KGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATKRPTSVVFIVPG 121
KG+KG++V+AGD P +V HLPV+CED+++PY+++PSK DLG+A +KRPT V+ + P
Sbjct: 73 KGEKGIMVLAGDTLPIEVYCHLPVMCEDRNLPYVYIPSKTDLGAAAGSKRPTCVIMVKPH 132
Query: 122 SNXXXXXXXXXXXXXXXFDEIVKEVSSL 149
+DE ++EV SL
Sbjct: 133 EE-----------YQEAYDECLEEVQSL 149
>CE19186 [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 163
Score = 83.2 bits (204), Expect = 1e-16
Identities = 37/115 (32%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Query: 10 EDNYEARLPAVLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXR-GVKEVVKALRKGDKGLV 68
+D Y+A V P A+P R G+K+V K LR+ +KG+
Sbjct: 29 KDEYQALCELVNPIAQPLANRKLAKKVYKLIKKASAGDKTLREGIKDVQKELRRNEKGIC 88
Query: 69 VIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATKRPTSVVFIVPGSN 123
++AG++ P DV SH+P +CE++ +PY+++PS++ LG A +RP+ ++F+ P +
Sbjct: 89 ILAGNVSPIDVYSHIPGICEEKEIPYVYIPSREQLGLAVGHRRPSILIFVKPSGD 143
>7294353 [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 160
Score = 77.4 bits (189), Expect = 6e-15
Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 12/147 (8%)
Query: 4 DKSVSTEDNYEARLPAVLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXR-GVKEVVKALRK 62
D ++ E++Y+ +L V AKP R G+K+V LRK
Sbjct: 21 DVTIKEEESYDDKLIFVNAIAKPMAGKKLAKKCYKLVKKAMKHKTFLRNGLKDVQTRLRK 80
Query: 63 GDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATKRPTSVVFIVPGS 122
G+ G+ + AGD+ P D++ HLP +CE++ +PY + PS+ DLG+A KR T + +
Sbjct: 81 GETGICIFAGDVTPVDIMCHLPAVCEEKGIPYTYTPSRADLGAAMGVKRGTVALLVRQNE 140
Query: 123 NXXXXXXXXXXXXXXXFDEIVKEVSSL 149
+DE+ +E+S+L
Sbjct: 141 E-----------YKDLYDEVKEELSAL 156
>7297543 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 160
Score = 68.6 bits (166), Expect = 3e-12
Identities = 31/62 (50%), Positives = 42/62 (67%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G +VV+AGD P +++ HLP+LCED++VPY+FV SKQ LG A
Sbjct: 69 KGANEATKTLNRGLADIVVLAGDAEPIEILLHLPLLCEDKNVPYVFVRSKQALGRACGVS 128
Query: 111 RP 112
RP
Sbjct: 129 RP 130
>SPAC607.03c [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 125
Score = 66.2 bits (160), Expect = 1e-11
Identities = 29/62 (46%), Positives = 40/62 (63%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G +V+A D P +++ HLP+LCED++VPY+FVPSK LG A
Sbjct: 34 KGANEATKTLNRGISEFIVMAADTEPIEILLHLPLLCEDKNVPYVFVPSKAALGRACGVS 93
Query: 111 RP 112
RP
Sbjct: 94 RP 95
>Hs4826860 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 128
Score = 66.2 bits (160), Expect = 1e-11
Identities = 30/62 (48%), Positives = 40/62 (64%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G +V+A D P ++I HLP+LCED++VPY+FV SKQ LG A
Sbjct: 37 KGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVS 96
Query: 111 RP 112
RP
Sbjct: 97 RP 98
>At5g20160 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 128
Score = 65.5 bits (158), Expect = 3e-11
Identities = 30/62 (48%), Positives = 40/62 (64%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G VV+A D P +++ HLP+L ED++VPY+FVPSKQ LG A
Sbjct: 37 KGANEATKTLNRGISEFVVMAADAEPLEILLHLPLLAEDKNVPYVFVPSKQALGRACGVT 96
Query: 111 RP 112
RP
Sbjct: 97 RP 98
>At4g22380 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 128
Score = 65.5 bits (158), Expect = 3e-11
Identities = 30/62 (48%), Positives = 40/62 (64%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G VV+A D P +++ HLP+L ED++VPY+FVPSKQ LG A
Sbjct: 37 KGANEATKTLNRGISEFVVMAADAEPLEILLHLPLLAEDKNVPYVFVPSKQALGRACGVT 96
Query: 111 RP 112
RP
Sbjct: 97 RP 98
>YEL026w [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 126
Score = 64.3 bits (155), Expect = 6e-11
Identities = 27/62 (43%), Positives = 40/62 (63%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G +++A D P +++ HLP+LCED++VPY+FVPS+ LG A
Sbjct: 35 KGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVS 94
Query: 111 RP 112
RP
Sbjct: 95 RP 96
>At4g12600 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 128
Score = 64.3 bits (155), Expect = 6e-11
Identities = 29/62 (46%), Positives = 40/62 (63%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G +V+A D P +++ HLP+L ED++VPY+FVPSKQ LG A
Sbjct: 37 KGANEATKTLNRGISEFIVMAADTEPLEILLHLPLLAEDKNVPYVFVPSKQALGRACDVT 96
Query: 111 RP 112
RP
Sbjct: 97 RP 98
>CE02283 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 128
Score = 63.5 bits (153), Expect = 1e-10
Identities = 28/62 (45%), Positives = 40/62 (64%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G E K L +G ++V+A D P +++ HLP+LCED++VPY+FV SK LG A
Sbjct: 37 KGANEATKTLNRGISEIIVMAADAEPLEILLHLPLLCEDKNVPYVFVRSKAALGRACGVT 96
Query: 111 RP 112
RP
Sbjct: 97 RP 98
>ECU07g0460 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 120
Score = 60.5 bits (145), Expect = 8e-10
Identities = 30/68 (44%), Positives = 42/68 (61%)
Query: 51 RGVKEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLGSAGATK 110
+G+ E K L KG LVVIA D+ PQ++ + LP++CED+ V ++ VPSK LG A
Sbjct: 33 KGINESTKCLSKGIALLVVIACDVEPQEITALLPIICEDKGVSFVHVPSKDALGVACGID 92
Query: 111 RPTSVVFI 118
RP + I
Sbjct: 93 RPIAACTI 100
>ECU11g0940 [A] KOG3167 Box H/ACA snoRNP component involved in ribosomal RNA
pseudouridinylation
Length = 109
Score = 59.3 bits (142), Expect = 2e-09
Identities = 27/84 (32%), Positives = 40/84 (47%)
Query: 20 VLPFAKPXXXXXXXXXXXXXXXXXXXXXXXXRGVKEVVKALRKGDKGLVVIAGDIFPQDV 79
++P A P G+K+ K + +G KGL+V+ D P D+
Sbjct: 1 MIPIASPLASESTEEMIAKLVRSQAERGGLATGIKKCQKRVLEGSKGLLVLTADTTPMDL 60
Query: 80 ISHLPVLCEDQSVPYIFVPSKQDL 103
I+HLP LCED+ Y+FV SK +
Sbjct: 61 ITHLPALCEDRGTKYVFVRSKSSI 84
>Hs22047689_1 [AJ] KOG3387 60S ribosomal protein 15.5kD/SNU13 NHP2/L7A family
(includes ribonuclease P subunit p38) involved in
splicing
Length = 387
Score = 49.7 bits (117), Expect = 1e-06
Identities = 25/51 (49%), Positives = 33/51 (64%)
Query: 54 KEVVKALRKGDKGLVVIAGDIFPQDVISHLPVLCEDQSVPYIFVPSKQDLG 104
KE K L +G G +V A D ++I HL +LCED++V Y+FV SKQ LG
Sbjct: 29 KEATKTLSRGISGFIVGAADAKLLEIILHLQLLCEDKNVFYVFVCSKQALG 79
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.136 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,448,139
Number of Sequences: 60738
Number of extensions: 194354
Number of successful extensions: 360
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 341
Number of HSP's gapped (non-prelim): 17
length of query: 149
length of database: 30,389,216
effective HSP length: 96
effective length of query: 53
effective length of database: 24,558,368
effective search space: 1301593504
effective search space used: 1301593504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)