ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII3876 good R KOG2238 General function prediction only Uncharacterized conserved protein TEX2, contains PH domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII3876 1365488 1367836 783
(783 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR091c [R] KOG2238 Uncharacterized conserved protein TEX2 conta... 474 e-133
SPBC23G7.06c [R] KOG2238 Uncharacterized conserved protein TEX2 ... 172 2e-42
CE28454 [R] KOG2238 Uncharacterized conserved protein TEX2 conta... 71 7e-12
CE28453 [R] KOG2238 Uncharacterized conserved protein TEX2 conta... 71 7e-12
At1g17820 [R] KOG2238 Uncharacterized conserved protein TEX2 con... 67 8e-11
At1g73200 [R] KOG2238 Uncharacterized conserved protein TEX2 con... 60 2e-08
Hs20559339 [R] KOG2238 Uncharacterized conserved protein TEX2 co... 59 2e-08
Hs8923804 [R] KOG2238 Uncharacterized conserved protein TEX2 con... 54 9e-07
7295025 [R] KOG2238 Uncharacterized conserved protein TEX2 conta... 53 2e-06
>YPR091c [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 770
Score = 474 bits (1219), Expect = e-133
Identities = 290/785 (36%), Positives = 427/785 (53%), Gaps = 110/785 (14%)
Query: 1 MTSLAGFIFVYVFGGLTFIPITIAIVFY-------LTSSPKKDVENEENDK-------LV 46
M SL F+ VY+ GG+TF+P+ + ++ L S+ KK+++++ D+ L
Sbjct: 1 MASLKVFLAVYLLGGITFLPLVLFTLYKIHLLYSNLKSASKKELDHDTADEIDEKTRLLA 60
Query: 47 VDVDSSFKAGDLNELKGVATKKQGYLHITRQFYPHQTDLDNQTENTDDAESNTTPPSAEQ 106
D+D FKA L E GV +G++ +T+Q+Y H +++ +N+++ + + T EQ
Sbjct: 61 RDIDPEFKARKLEEQLGVKVFNKGWITVTKQYYYHSSEVAVILKNSNNNKDSDTALQ-EQ 119
Query: 107 QRTRDKLKKKDKFYAVLKHGNLFLYKDFSPEAGPQQVIVLSDAFISIWPRTVSPQDDTPI 166
R LKKK +F+AVL+HGNLFLYKD S A I L + FI+IWPR +
Sbjct: 120 ILQRTDLKKKQRFFAVLRHGNLFLYKDDSQNANLVHAISLQNRFITIWPR-FDELGKEEL 178
Query: 167 PDGSLFTKKTCISIWKKHTAYMDQSNR------------LQFRRGG-------------- 200
PD SLFTK+TCI+I+K +D N + G
Sbjct: 179 PDASLFTKRTCIAIFKNDLVSIDSKNHNVILPHFDPLTSAESNNGDISTNDTTHEYQSQF 238
Query: 201 -PSDQFFIYLDLNTDKEDWYFALIQATKMEKGPRSPVNSSHFEVEKALSAEYAAQTAHFK 259
S+QFF+Y D N DKEDWY+ LI A+K NS+ L +A AH K
Sbjct: 239 HSSNQFFLYFDNNMDKEDWYYQLINASK---------NSNSLSTG-LLDPNVSANAAHLK 288
Query: 260 TKDMLYLIQTLNSTEGQHSSQWFNALIGRLFLSLQQTETLSNAVRERIYKKLKKINKPGL 319
TKDML LIQ +NSTE Q +++W NAL+GRLFLSLQQT+TL+ + E+I KKL KI PG
Sbjct: 289 TKDMLQLIQDINSTENQLTTKWLNALLGRLFLSLQQTDTLNKFIHEKICKKLNKIKTPGF 348
Query: 320 LDDFSIEKVTVGNSAPVISNPKLLDLTPEGQTRVSFDFLYTGHLHLIIATKMNINLGSRF 379
LDD +EKV VG+SAP+ ++P+LL+L+PEG T+++ D Y G+L +IIATK +INLGSRF
Sbjct: 349 LDDLVVEKVDVGDSAPLFTSPELLELSPEGSTKIAIDVQYRGNLTIIIATKASINLGSRF 408
Query: 380 KKREMDIKLSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMV 439
K+RE+ ++LSI +K+ GP++ LIKPPP+NR+WYAF+TEP++D ++EP+VS+ +LS N+V
Sbjct: 409 KQREVSLQLSIKIKEFSGPLLFLIKPPPSNRIWYAFRTEPIMDFEIEPIVSSSKLSYNVV 468
Query: 440 TNMIKSKFKEAIKESIVLPYMDDMVFYKTPSELYRGGIWESTKQKKDTSYTEDFEYIKSE 499
TN IKSKF EA+KES+V+P+MDD+VFY TP+E+YRGGIWE +D E
Sbjct: 469 TNAIKSKFAEAVKESLVVPFMDDIVFYPTPNEVYRGGIWEE----------QDPEAAARA 518
Query: 500 RQFNTGSSVRENNDISNTNLAERQSTNSAVDSPTVEESESTINESYNTDQPQTSTDSTRS 559
R S D++NT+ E T + + + + D+ S
Sbjct: 519 RTAAAAS------DMNNTSAKEHLEALQEGGMKTQSRIKKALRPERKKENLKDLVDA--S 570
Query: 560 FLKNKSNDDSNVSIRSRSSVDST-NSNATKRYLQTGMKKIGRWYKEQV-----------V 607
+ K+ + V+ + V S+ NS +++Y + +KKIGRWYK+ V +
Sbjct: 571 GVATKTTTQTTVTTATNDDVSSSENSTKSRKYFKNSIKKIGRWYKDNVGNSSDTEDMDEI 630
Query: 608 TVKESLNSD----EELHHP-------------DEPEGTEDQVGVISTKVAEKSELLENEA 650
V++ N D E +P P + +S K+ + E
Sbjct: 631 DVQDKKNDDSADERESDNPILTSNPKMISNRRPVPRRPSQPLNTLSPKLEGRKEKDTENF 690
Query: 651 SIPDAASSLKVETSFKTTEKPTTPEMITNRRVPRSKNSSIDNSKQETSH-HTSESHRAEM 709
+P +AS++ F E NR+ S N S ++ K H S+ ++
Sbjct: 691 PVPPSASNMNASKMFANKE---------NRKFSVSSNDSQNSLKNGDPHVKASKLESSQA 741
Query: 710 FVNRT 714
FV +T
Sbjct: 742 FVKKT 746
>SPBC23G7.06c [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 745
Score = 172 bits (435), Expect = 2e-42
Identities = 144/514 (28%), Positives = 235/514 (45%), Gaps = 66/514 (12%)
Query: 279 SQWFNALIGRLFLSLQQTETLSNAVRERIYKKLKKINKPGLLDDFSIEKVTVGNSAPVIS 338
+ W NA IGR+FL + +TE + V E++ KKL +I PG++ D + V VG + P ++
Sbjct: 208 TDWLNAFIGRIFLGIHKTEGFKSLVVEKLTKKLSRIKTPGIMTDVKVIDVDVGEAIPTVN 267
Query: 339 NPKLLDLTPEGQTRVSFDFLYTGHLHLIIATKMNINLGSRFKKREMDIKLSITVKKVEGP 398
K L+ G+ VS D Y G T NI GS F + + + L I + V G
Sbjct: 268 GLKFESLSNGGELIVSADIWYEGDCSFKAETTANIKFGSHFPSKTVPLALVIRLTHVSGK 327
Query: 399 IVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNMIKSKFKEAIKESIVLP 458
+ +LIKPPP+NR+WYAF +P L + VEP+V+ +QL+NN + N I K E + E+IV+P
Sbjct: 328 VRLLIKPPPSNRVWYAFYEKPRLHLIVEPMVARKQLTNNYLINFITQKLVELVHETIVMP 387
Query: 459 YMDDMVFYKTPSELYRGGIWESTKQKKDTSYTEDFEYIKSERQFNTGSSVRENNDISNTN 518
M+D+ F+ +GG+W+ + T + K+ER+ +G S + + N +
Sbjct: 388 NMNDLAFFIDNEAPIKGGLWDIELFRAPTIQKPAEKDAKAERK-KSGLSSSTSEESLNRH 446
Query: 519 LAERQSTNSAVDSPTVE-------ESESTINESYNTD-----QPQTSTDSTRSFLKNKSN 566
+++R S+NS +P+ E S I N D + S S L NKS+
Sbjct: 447 ISKR-SSNSNDTAPSSHIIADKNLEPTSNIQLKKNPDGNLVETSELSDSDENSVLSNKSS 505
Query: 567 DDSNVSIRSRSSVDSTNSNATKRYLQTGMKKIGRWYKEQVVTVKESLNS-DEELHHPDEP 625
S + + S + T+S + K + V++SL + + H P
Sbjct: 506 TLSKKVVENTSPLKYTHSAS----------------KSFIGEVQDSLQALKTKAHKPRSI 549
Query: 626 EGTEDQVGVIST-----KVAEKSELLENEASIPDAASSL-KVETSFKTTEKPTTPEMITN 679
G Q + T VA+KS + DA S + K+++++ +P I
Sbjct: 550 GGDSSQTTLSETTKKYGSVAKKSFF----QGVSDAKSFVKKIKSTYIDDSSSNSPSDI-- 603
Query: 680 RRVPRSKNSSIDNSKQETSHHTSESHRAEMFVNRTRARSTSGSYSPTSPDVYRRHEMSYS 739
N S D+++ S +A+ ++ + S S S +S Y+ E
Sbjct: 604 -----ESNYSADDNEISKS-------KAQNAIDFNVTNTHSPSRSISSEKSYKAAERGQQ 651
Query: 740 FTNNE---NLNPHSITSSDILEEAENMIPEINAQ 770
+N+ +LNP+ EAE P N+Q
Sbjct: 652 DKHNDVLVDLNPN--------VEAEKSNPHSNSQ 677
>CE28454 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 925
Score = 70.9 bits (172), Expect = 7e-12
Identities = 29/79 (36%), Positives = 54/79 (67%)
Query: 386 IKLSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNMIKS 445
+ L++ V++VEGP+ I PPP++RLWYAF+ P+L + P V R + + V+ I++
Sbjct: 831 LMLNVEVEEVEGPMTCNIPPPPSDRLWYAFRRRPILKLRAVPQVGDRSVDLSTVSEWIET 890
Query: 446 KFKEAIKESIVLPYMDDMV 464
K ++ +++++V P MDD++
Sbjct: 891 KLRQVLEKNLVCPNMDDII 909
>CE28453 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 876
Score = 70.9 bits (172), Expect = 7e-12
Identities = 29/79 (36%), Positives = 54/79 (67%)
Query: 386 IKLSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNMIKS 445
+ L++ V++VEGP+ I PPP++RLWYAF+ P+L + P V R + + V+ I++
Sbjct: 782 LMLNVEVEEVEGPMTCNIPPPPSDRLWYAFRRRPILKLRAVPQVGDRSVDLSTVSEWIET 841
Query: 446 KFKEAIKESIVLPYMDDMV 464
K ++ +++++V P MDD++
Sbjct: 842 KLRQVLEKNLVCPNMDDII 860
>At1g17820 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 797
Score = 67.4 bits (163), Expect = 8e-11
Identities = 60/284 (21%), Positives = 128/284 (44%), Gaps = 37/284 (13%)
Query: 383 EMDIKLSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNM 442
++ I LSI V + G + + +KPPP+++LW+ F + P ++ D+ V +++N+ V
Sbjct: 508 QVPISLSIRVSSLRGTLRVHMKPPPSDQLWFGFTSMPDIEFDLASSVGEHKITNSHVAMF 567
Query: 443 IKSKFKEAIKESIVLPYMDDMVFYKTPSE----LYRGG---IWESTKQKKDTSYTED--- 492
+ ++FK AI+E++VLP + + +E + R +W + + +TS+ +
Sbjct: 568 LINRFKTAIREAVVLPNCESLTIPWMIAEKDDWVQRKAAPFMWLNQENDHNTSHATEARS 627
Query: 493 --------FEYIKSERQFNTGSS----VRENNDISNTNLAERQSTNSAVDSPTVEESEST 540
F +++E+ T ++ + E +++++ A+ + A T + ++T
Sbjct: 628 KSDKPPTSFSCLQAEQMQRTANATQKIISEIGTLASSSCAQSEQVQKAA---TAFQKQNT 684
Query: 541 INESYNTDQPQTSTDSTRSFLKNKSNDDSNVSIRSRSSVDSTNSNATKRYLQTGMKKIGR 600
E+ + ST T K+ + + + S S+ TNS + R +
Sbjct: 685 EAEAIMSTPLSNSTTVTIENDKSLEELKTPLLVPSSSNKQETNSRGSSREVSA------- 737
Query: 601 WYKEQVVTVKESLNSDEELHHPDEPEGTEDQVGVISTKVAEKSE 644
V + S+ S EE + +G ++ + K+ EK E
Sbjct: 738 -----VQSPSRSVASSEEDDSRGKKQGRRARMLDLGKKMGEKLE 776
>At1g73200 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 779
Score = 59.7 bits (143), Expect = 2e-08
Identities = 46/202 (22%), Positives = 91/202 (44%), Gaps = 33/202 (16%)
Query: 369 TKMNINLGSRFKKR---------EMDIKLSITVKKVEGPIVILIKPPPTNRLWYAFQTEP 419
TK + GS++K ++ I LSI V + G + + +KPPP+++LW+ F + P
Sbjct: 494 TKTGSSNGSKWKSMLKNIVEQVSQVPITLSIGVSSLRGTLCVHMKPPPSDQLWFGFTSMP 553
Query: 420 LLDIDVEPVVSTRQLSNNMVTNMIKSKFKEAIKESIVLPYMDDMVFYKTPSELYRGGIWE 479
++ ++ V +++N+ V + ++FK AI++ +VLP + + I
Sbjct: 554 DIEFNLVSSVGEHKITNSHVAMFLVNRFKTAIRDVMVLPNCESVT------------IPW 601
Query: 480 STKQKKDTSYTEDFEYIKSERQFNTGSSVRENNDISNTNLAERQSTNSAVDSPTVEESES 539
T +K D ER + +++ NL ++ + A PT E+ +
Sbjct: 602 MTAEKDDW----------VERNVAPFMWLNQDSTSDRENLEAAEAKSKADKPPTSEQMQK 651
Query: 540 TIN--ESYNTDQPQTSTDSTRS 559
T+N + ++ S D+ S
Sbjct: 652 TVNIPQKPRIEEESVSADTAPS 673
Score = 51.2 bits (121), Expect = 6e-06
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 283 NALIGRLFLSLQQTETLSNAVRERIYKKLKKINKPGLLDDFSIEKVTVGNSAPVISNPKL 342
N ++ RLF ++Q L N VRERI + + + P + + V +GN P I ++
Sbjct: 338 NVVLSRLFFDVKQNTVLKNLVRERIQRIMSNMRIPSYIGELICCDVDIGNLPPYIHGTRI 397
Query: 343 LDLTPEGQTRVSFDFLYTGHLHLIIATKMNINLGSRFKKREMDIKLSITVKKVE 396
L + G D YTG L + T+++ RE D++ I K++
Sbjct: 398 LPMEMNGVWAFEIDIEYTGGAGLEVETRVD--------AREEDLQKGIAEGKLQ 443
>Hs20559339 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 845
Score = 59.3 bits (142), Expect = 2e-08
Identities = 24/76 (31%), Positives = 48/76 (62%)
Query: 388 LSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNMIKSKF 447
L++ V++ G + + I PPPT+R+WY F+ P +++ P + R+++ VT+ I+ K
Sbjct: 741 LTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELKARPKLGEREVTLVHVTDWIEKKL 800
Query: 448 KEAIKESIVLPYMDDM 463
++ ++ V+P MDD+
Sbjct: 801 EQEFQKVFVMPNMDDV 816
>Hs8923804 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH
domain
Length = 229
Score = 53.9 bits (128), Expect = 9e-07
Identities = 24/76 (31%), Positives = 48/76 (62%), Gaps = 1/76 (1%)
Query: 388 LSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNMIKSKF 447
L++ V++ G + + I PPPT+R+WY F+ P +++ P + R+++ VT+ I+ K
Sbjct: 126 LTVEVQECRGTLAVNIPPPPTDRVWYGFRKPPHVELK-GPKLGEREVTLVHVTDWIEKKL 184
Query: 448 KEAIKESIVLPYMDDM 463
++ ++ V+P MDD+
Sbjct: 185 EQEFQKVFVMPNMDDV 200
>7295025 [R] KOG2238 Uncharacterized conserved protein TEX2 contains PH domain
Length = 1060
Score = 53.1 bits (126), Expect = 2e-06
Identities = 26/78 (33%), Positives = 47/78 (59%)
Query: 385 DIKLSITVKKVEGPIVILIKPPPTNRLWYAFQTEPLLDIDVEPVVSTRQLSNNMVTNMIK 444
+I L + +K + + + PPP++R+W +F+ P L I +P V + + ++VTN+I+
Sbjct: 963 NITLRVDLKGLVARGTLNVPPPPSDRVWVSFRGPPRLWISTKPQVGDKSVDWSIVTNVIE 1022
Query: 445 SKFKEAIKESIVLPYMDD 462
SK EA+ + +V P M D
Sbjct: 1023 SKLCEAVNKFLVYPNMVD 1040
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.128 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,781,325
Number of Sequences: 60738
Number of extensions: 2087860
Number of successful extensions: 7465
Number of sequences better than 1.0e-05: 9
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 7437
Number of HSP's gapped (non-prelim): 20
length of query: 783
length of database: 30,389,216
effective HSP length: 114
effective length of query: 669
effective length of database: 23,465,084
effective search space: 15698141196
effective search space used: 15698141196
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)