ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4033 good TZ KOG4035 Cytoskeleton Coeffector of mDia Rho GTPase, regulates actin polymerization and cell adhesion turnover
r_klactIII4033 good TZ KOG4035 Signal transduction mechanisms Coeffector of mDia Rho GTPase, regulates actin polymerization and cell adhesion turnover
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4033 1424756 1423305 -484
(484 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL146w [TZ] KOG4035 Coeffector of mDia Rho GTPase regulates act... 346 4e-95
SPBC24C6.10c [TZ] KOG4035 Coeffector of mDia Rho GTPase regulate... 81 4e-15
7290878 [TZ] KOG4035 Coeffector of mDia Rho GTPase regulates act... 50 1e-05
>YDL146w [TZ] KOG4035 Coeffector of mDia Rho GTPase regulates actin
polymerization and cell adhesion turnover
Length = 491
Score = 346 bits (888), Expect = 4e-95
Identities = 185/454 (40%), Positives = 273/454 (59%), Gaps = 12/454 (2%)
Query: 12 LVEFWEKLEELLAEVNVRN--ESEVNSALVSFVKITADHYSSLIKCDQDLYRIGLMLVES 69
++EFWEK E + A + N ES VNS+LV+++K D Y I D+DLYR+ L+L+ES
Sbjct: 18 IIEFWEKTESI-ANIPKENLDESHVNSSLVAYLKFATDSYKVFINTDRDLYRMSLILLES 76
Query: 70 PMFQQTTDFCXXXXXXXXXXXXXXXXXXXXXXXXXXXXCKVDLNALDIILENQGFLVLYN 129
+F+ +FC K ++ +L+I+L+ QGF V YN
Sbjct: 77 SLFEFKKEFCLSKLQSLLNIDLLEMNMKFIIVYILLCEAKKNVYSLEIMLKFQGFTVFYN 136
Query: 130 NIYSNFAYLNKYGDEYTGVP---YQANEYHDKAQEDPKK----DTNLEIIEDIKHLTTIL 182
+Y+ FAYL+KYG E T Y +N D D +L II+++K ++T+L
Sbjct: 137 TLYTQFAYLSKYGKERTVASKHQYNSNNSSTGTSLDSLDRSLTDIDLGIIDEMKQISTVL 196
Query: 183 IDIMYQFFKYSKCQISNIQMIDDFFIYYLVSSIRSDVVDDILNNVKFKLLLALNEQYMIF 242
+D+++Q KY KC I+N+Q++DDFF+YY++ S+RSD +DD+ NN +FKLLLALNEQYM+F
Sbjct: 197 MDLLFQIMKYCKCVIANLQIVDDFFVYYMMESMRSDTMDDMFNNAEFKLLLALNEQYMMF 256
Query: 243 QYEFDIENKAYEFLLNHNMSKDFIGLLLLKFNRETDTSLLIMICKVIYIILT-KDLKVAK 301
E+DIENK Y++L+N ++S+ F LLLLKFNR +D L IM+CK+IY+ILT +
Sbjct: 257 AKEYDIENKVYKYLINGSVSRCFTELLLLKFNRASDPPLQIMMCKIIYLILTPRGDYSPM 316
Query: 302 DFFYLNDLHVFVDVLLRNLNNISDNEEILRNTYLRVLTPLLNNTELAATKYHRSEISTTL 361
+FFY NDL V +DVL+R L NIS++EE+LRNT LRVL PLL NT+L+ T Y + +++ L
Sbjct: 317 NFFYTNDLRVLIDVLIRELQNISEDEEVLRNTLLRVLIPLLKNTQLSKTHYRKDDLNKLL 376
Query: 362 KFFSDVDNFCSIEKATPLQKTTARLAAKCLHEVKWLEQENQFSSDQNDXXXXXXXXXXXX 421
+ S +DN C A + T L+ KCL ++ WLE + S +
Sbjct: 377 NYLSTLDNICVDSPALHEHQVTVALSRKCLQQIPWLETPSTPSDGGSSVSSNNTSRNSSI 436
Query: 422 XXXNTP-LEPVMSTTPHLYSNLQNSYSADSINHK 454
TP + +++ HLYSN + SA+S+ +
Sbjct: 437 VALGTPDNQNILARKGHLYSNRELDVSAESLTKR 470
>SPBC24C6.10c [TZ] KOG4035 Coeffector of mDia Rho GTPase regulates actin
polymerization and cell adhesion turnover
Length = 374
Score = 80.9 bits (198), Expect = 4e-15
Identities = 59/225 (26%), Positives = 110/225 (48%), Gaps = 17/225 (7%)
Query: 185 IMYQFFKYSKCQISNIQMIDDFFIYYLVSSIRSDVVDDILNNVKFKLL--LALNEQYMIF 242
++Y + + +++ ID++F+ L + D+ +++ +L L++NEQ+M+
Sbjct: 150 LVYYICRSRRLSPTDLVAIDEYFLVNLFKTSEEAWNDEDMDSFGMCVLTLLSINEQFMLV 209
Query: 243 QY----EFDIENKAYEFLLNHNMSKDFIGL-LLLKFNRETDTSLLIMICKVIYIILTKDL 297
+ F+I N + L + + L+ NRE D ++I K ++++ T
Sbjct: 210 RLASKGSFEIANGIMDLLSSSKVDNGIYSEGLVFTLNREKDPRSRMLILKQLFLLFTTP- 268
Query: 298 KVAKDFFYLNDLHVFVDVLLRNLNNISDNEEILRNTYLRVLTPLLNNTELAATKYHRSEI 357
+ FY NDL+V +D+ +R +NNI D LR YL+VL PLL NT++ ++++
Sbjct: 269 -ATYEIFYTNDLNVLIDIFIREINNIPDELSDLRYAYLQVLIPLLENTQVRHPPHYKT-- 325
Query: 358 STTLKFFSDVDN--FCSIEKATPLQKTTARLAAKCLHEVKWLEQE 400
K D N S K++ ++ A + EV WL+QE
Sbjct: 326 ----KCIVDAVNNVLISHSKSSNMEDARTTDVAIRVLEVPWLQQE 366
>7290878 [TZ] KOG4035 Coeffector of mDia Rho GTPase regulates actin
polymerization and cell adhesion turnover
Length = 801
Score = 49.7 bits (117), Expect = 1e-05
Identities = 55/216 (25%), Positives = 100/216 (45%), Gaps = 25/216 (11%)
Query: 169 LEIIEDIK-HLTTI-----LIDIMYQFFKYSKCQISNIQ-MIDDFFIYYLVSSIRSDVVD 221
LEI+ED+K H + + L+ ++ F + N Q + F +L+ + +
Sbjct: 572 LEIVEDMKTHFSNLDRFKQLVKMLTIIFSLGQPMPVNHQDYLGVHFASFLLEIVEGNN-P 630
Query: 222 DILNNVKFKLLLALNEQYMIFQYEFDIENKAYEFLLNHNMSKDFIGLLLLKFNRETD-TS 280
++L ++ L+LA N+Q+ Y IE + N +K F LLL NRE D T
Sbjct: 631 EVLVDMVIALILAFNQQFSEHTYNVIIEG-----MQNLPSAKVFTEKLLLLLNREDDPTR 685
Query: 281 LLIMICKVIYIILTKDLKV-----AKDFFYLNDLHVFVDVLLRNLNNISDNEEILRNTYL 335
LL + + +L + + FY ND+ V +D+++R L+++ D R YL
Sbjct: 686 LLKHPNEHMNTVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDL-DAGSTTRPCYL 744
Query: 336 RVLTPLLNNTELAATKYHRSEISTTLKFFSDVDNFC 371
+ +L NT ++ + ++ +K F+ + FC
Sbjct: 745 ELCRRILRNTNYQEHQHRKHDL---MKIFTRI--FC 775
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,582,780
Number of Sequences: 60738
Number of extensions: 971283
Number of successful extensions: 2538
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2530
Number of HSP's gapped (non-prelim): 4
length of query: 484
length of database: 30,389,216
effective HSP length: 110
effective length of query: 374
effective length of database: 23,708,036
effective search space: 8866805464
effective search space used: 8866805464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)