ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4057 good R KOG2173 General function prediction only Integral membrane protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4057 1433032 1430309 -908
(908 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL149w [R] KOG2173 Integral membrane protein 793 0.0
SPBC15D4.07c [R] KOG2173 Integral membrane protein 454 e-127
At2g31260 [R] KOG2173 Integral membrane protein 272 1e-72
7302947 [R] KOG2173 Integral membrane protein 220 7e-57
Hs13129082 [R] KOG2173 Integral membrane protein 187 8e-47
CE20100 [R] KOG2173 Integral membrane protein 170 1e-41
Hs20542893 [R] KOG2173 Integral membrane protein 145 2e-34
>YDL149w [R] KOG2173 Integral membrane protein
Length = 997
Score = 793 bits (2049), Expect = 0.0
Identities = 431/886 (48%), Positives = 559/886 (62%), Gaps = 62/886 (6%)
Query: 3 DSQDKVNGGSKNTFLSRVFGVHSSAVENSLDAAEMSHITMPTEQDFSNYAE--------- 53
D N KNTFLSR+FG+ S V SL++ EMS+ +P + S+
Sbjct: 4 DEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLPDIERGSSLLHSTNDSREDV 63
Query: 54 DEGNVRLIXXXXXXXXXXXXXXXXXXLIQQPQSIRFDTASDGMATIQSESEPDXXXXXXX 113
DE ++R+ + Q + + DG + S + +
Sbjct: 64 DENDLRVPESDQGTSTEEEDEVDEEQV--QAYAPQISDGLDGDHQLNSVTSKENVLETEK 121
Query: 114 XXXXXXXXFSDQDLASSVSKYGQPSSSEDEEPLSNRDSNRGSDETIPFIGRQRLNL---- 169
S D SV K GQ SS E+E+ + +N G D+ P + +++
Sbjct: 122 SNLERLVEGSTDD---SVPKVGQLSSEEEED--NEFINNDGFDDDTPLFQKSKIHEFSSK 176
Query: 170 ------GGKNPITGATKSTKNPSESRVFERLLGNSPA------KMFRNNGRPNNLEESFL 217
GK P+ +N R ++L +S A K N R N +
Sbjct: 177 KSNTIEDGKRPLF-FRHILQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQKHG 235
Query: 218 FRKPSVAEQ----SGPGKSTH-----FNLKPPPIFXXXXXXXXXXXXXXXXXXPKERALW 268
+ A Q P +T+ F L+ P + KERALW
Sbjct: 236 TKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALW 295
Query: 269 KWANIENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRLSSS 328
KWAN+ENLD FLQ VY YYLGNGFYCII EK++++ T+LFVVF+STYMGHC+DYS+L +S
Sbjct: 296 KWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKLPTS 355
Query: 329 HTFEEIHIEQCYKTQISPTAKVFLWIFYAFIGLKVLQLYFDVKALKDIRNFYNYLLSISD 388
H +I I++CY I+ K FLW+FY F+ LK++QLYFDV+ L +++NFY YLL+ISD
Sbjct: 356 HRVSDIIIDKCYSNSITGFTKFFLWMFYFFVILKIVQLYFDVQKLSELQNFYKYLLNISD 415
Query: 389 KDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRKENFVIALYDNN 448
+LQT+PWQ+VIQQL+ LKDQNA+TAN EVKAKNR+ AHDVANRIMR+EN++IALY+++
Sbjct: 416 DELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSD 475
Query: 449 ILDLSLPVPLLRTCALTKTLEWNINLCILGFAFNEKGYLKQAFLRESQREYLGEELKKRF 508
IL+LSLP+PL RT LTKTLEWNINLC++GF FNE G++KQ+ L+ SQRE+ EEL+KRF
Sbjct: 476 ILNLSLPIPLFRTNVLTKTLEWNINLCVMGFVFNESGFIKQSILKPSQREFTREELQKRF 535
Query: 509 VLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPIAEWKFREYNELYHIF 568
+LAGFLNIIL+PFLVTYFVLL FFRYFNEYKTSPGSIG+RQYTPIAEWKFREYNELYHIF
Sbjct: 536 MLAGFLNIILAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIF 595
Query: 569 QKRMRLSMIIADNYVNQFPNTLLSLTLSFIQFVSGSFVAILGILTIFDPDNFLNFEITPD 628
+KR+ LS +A+ YV+QFP +L L F+ F+ GSFVAIL LT+FDP+NFLNFEIT D
Sbjct: 596 KKRISLSTTLANKYVDQFPKEKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSD 655
Query: 629 RTVLFYMTVFGTLWAVCHSSINDEYTVLKPEETLEELVSYTHYAPKEWKGKYHTEDIKNE 688
R+V+FY+T+ G +W+V ++I EY V PEETL+EL YTHY PKEW+G+YH E+IK E
Sbjct: 656 RSVIFYITILGAIWSVSRNTITQEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLE 715
Query: 689 FCRLYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFRECTVYEEGLGYVCKYAMF 748
FC+LYNLRI +LLREL S++ITPF+LWFSLP ++ RI+DFFRE + Y +GLGYVCKYAMF
Sbjct: 716 FCKLYNLRIVILLRELTSLMITPFVLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMF 775
Query: 749 EATKI--------DKGTKAKK---------QTKRMFSQAEQDDSETESDEGVNKMLQSYM 791
I D+ + KK +KR +D S + D NKMLQSY+
Sbjct: 776 NMKNIDGEDTHSMDEDSLTKKIAVNGSHTLNSKRRSKFTAEDHS--DKDLANNKMLQSYV 833
Query: 792 YFVDDYKNAGNAVGKNQLPASPIEPSYHPYSSTKD-YSWKTQFALG 836
YF+DDY N+ N GK QLPA P+ S + YSW+ QF G
Sbjct: 834 YFMDDYSNSENLTGKYQLPAKKGYPNNEGDSFLNNKYSWRKQFQPG 879
>SPBC15D4.07c [R] KOG2173 Integral membrane protein
Length = 702
Score = 454 bits (1169), Expect = e-127
Identities = 223/492 (45%), Positives = 326/492 (65%), Gaps = 10/492 (2%)
Query: 263 KERALWKWANIENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDY 322
++R LW+WAN+ENLD+FLQQVY YY G G CII ++ + T+ FV+ +T++ CID+
Sbjct: 170 RDRVLWRWANVENLDSFLQQVYTYYTGKGLSCIIVHRLFQILTVSFVIGFTTFITSCIDW 229
Query: 323 SRLSSSHTFEEIHIEQCYKTQISPTAKVFLWIFYAFIGLKVLQLYF--DVKALKDIRNFY 380
++ + + QC Q+SP + LW+F +F L L +Y+ D+ L +R FY
Sbjct: 230 PAVTPHGSLAGVTKSQCI-AQMSPITYLVLWLFLSF--LLALWIYYLTDIPRLWQMREFY 286
Query: 381 NYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKN---RLSAHDVANRIMRK 437
+ L I+ D+ T+ WQ V+ +L+ LK+ NA+TA V + + RL A+ +ANRIMRK
Sbjct: 287 IHALKIATADMPTVSWQRVLYRLLKLKNVNALTAEDGRVVSLHNMKRLDAYAIANRIMRK 346
Query: 438 ENFVIALYDNNILDLSLPVPLLRTCALTKTLEWNINLCILGFAFNEKGYLKQAFLRESQR 497
+N+ IAL +N I+++ LP LL LT T EWNIN CI F F+E+G L+ AF + R
Sbjct: 347 DNYFIALINNGIINIELP--LLHRRILTHTTEWNINWCIFNFVFDEQGQLRSAFRNPNSR 404
Query: 498 EYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPIAEWK 557
+ L EEL++RF++AGFLN + +P + Y V+ NFFRYFNEY +PG++ +R+YTP+A W
Sbjct: 405 KRLSEELRRRFIVAGFLNCLFAPIVAIYLVIHNFFRYFNEYHKNPGALSTRRYTPLALWT 464
Query: 558 FREYNELYHIFQKRMRLSMIIADNYVNQFPNTLLSLTLSFIQFVSGSFVAILGILTIFDP 617
FREYNEL H F +R+ S A +YV+QFP+ + +I F+ GSF AIL I+T+FDP
Sbjct: 465 FREYNELQHFFDERINDSYAAASHYVSQFPDFNMIRLFKYISFILGSFTAILVIITVFDP 524
Query: 618 DNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTVLKPEETLEELVSYTHYAPKEWK 677
+ + FEIT DR+VLFY+ +FG+L AV S I DE V PE+ L ++++THY P W
Sbjct: 525 ELMVTFEITKDRSVLFYLGLFGSLIAVSRSIIPDETLVFAPEKALRRVITFTHYMPGWWS 584
Query: 678 GKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFRECTVYEE 737
H++ ++ EFC LY+ RI LL E++ I++TP +L+F+ P S+ I+DFFRE T+ E
Sbjct: 585 DNMHSKAVQQEFCSLYSYRIVNLLWEILGILLTPVLLFFTFPSCSQDIVDFFREHTINVE 644
Query: 738 GLGYVCKYAMFE 749
G+GYVC YA+F+
Sbjct: 645 GVGYVCSYAVFQ 656
>At2g31260 [R] KOG2173 Integral membrane protein
Length = 865
Score = 272 bits (696), Expect = 1e-72
Identities = 171/570 (30%), Positives = 302/570 (52%), Gaps = 60/570 (10%)
Query: 273 IENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRLSSSHTFE 332
I +LD F++++Y YY G +CII + + L ++ F++ S + +D++ L ++
Sbjct: 67 IADLDLFVERLYSYYRDKGLWCIIVKWAVELLSLGFIICFSGFFLLYVDWNGLQNAKCGM 126
Query: 333 E----------IHIEQCYKTQISP----TAKV--FLWIFYAFIGLKVLQLYFDVKALKDI 376
+ + E + +SP TA + +L +F + L+ + +K D
Sbjct: 127 DAVESGTKPCDLVKEAIHPHPLSPFTLTTAIIVGYLALFSVYWLFCFLRFFAQLKDTLDF 186
Query: 377 RNFYNYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMR 436
R+FY L ++D ++ T+PW +V++++V L+ + LSAHD+ R+MR
Sbjct: 187 RHFYYNNLHVTDNEILTMPWATVLEKVVQLQSSQCLCV-------VKDLSAHDMVMRLMR 239
Query: 437 KENFVIALYDNNILDLSLPV--------PLLRTC--------ALTKTLEWNINLCILGFA 480
KEN++I + + +L S P+ P +++ LTKTLEW +N CIL
Sbjct: 240 KENYLIGMLNKGLL--SFPISHWIPGAGPAVKSAPDGTQYHLVLTKTLEWTLNWCILQSM 297
Query: 481 FNEKGYLKQAFLRESQREYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKT 540
F+ +++ F+ LKKR + G ++LSPFLV + ++ F R+ ++
Sbjct: 298 FDCNFRVRRDFVSNPTT------LKKRLFVVGLAMLLLSPFLVIFMLVYLFLRHAEQFYN 351
Query: 541 SPGSIGSRQYTPIAEWKFREYNELYHIFQKRMRLSMIIADNYVNQFPNTLLSLTLSFIQF 600
P + SR+++ +++W FRE+NE+ H+F+ R+ S++ A Y+ QFP+ ++S+ F+ F
Sbjct: 352 HPSTASSRRWSNLSKWLFREFNEVDHLFKHRINSSVVHASEYLKQFPSPIISIIAKFVSF 411
Query: 601 VSGSFVAILGILTIFDPDNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTVLKPEE 660
VSG F A+L I+ F ++ L I R + +Y VFGT+ A+ ++I+DE VL P
Sbjct: 412 VSGGFAAVL-IIIAFLEESLLEGHIF-GRNLFWYAAVFGTITAISRAAISDELLVLDPVG 469
Query: 661 TLEELVSYTHYAPKEWKGKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILWFSLPK 720
T+ +V THY PK W+GK + +D++ E L+ +LL E+ SI ITPF+L F +PK
Sbjct: 470 TMSLVVQNTHYMPKRWRGKENKDDVRLELETLFQYTGMMLLEEIASIFITPFLLMFVVPK 529
Query: 721 NSERIIDFFRECTVYEEGLGYVCKYAMFEATKIDKGTKAKKQTKRMFSQAEQDDSETESD 780
+ I+ F ++ TV EG+G+VC ++ F + K + ++ EQ S+
Sbjct: 530 RVDDILQFIKDFTVDIEGVGHVCSFSAF---YFENHGNIKYGSPHNATRREQRSSQ---- 582
Query: 781 EGVNKMLQSYMYFVDDYKN-AGNAVGKNQL 809
KM +S++ F Y + +++GK L
Sbjct: 583 ---GKMEKSFLSFQSSYPSWESDSLGKQFL 609
>7302947 [R] KOG2173 Integral membrane protein
Length = 845
Score = 220 bits (561), Expect = 7e-57
Identities = 133/533 (24%), Positives = 258/533 (47%), Gaps = 31/533 (5%)
Query: 269 KWANIENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRLSSS 328
+W +IE+LD+F ++Y+Y +GF I+ ++++ + FVV++ ++ HC+ + L
Sbjct: 87 RWNHIEDLDSFFSRMYQYQQKHGFTVIVVDEMLQVLEFGFVVWLLAFVMHCVRFDVLFGD 146
Query: 329 HTFEEIHIEQCYKTQIS-PTAKV---FLWIFYA-------FIGLKVLQLYFDVKALKDIR 377
++ + + + PT + F W+ Y ++G+++L++ + + DI+
Sbjct: 147 TPPGGLNPNKTTLSDVMYPTGECLANFTWVTYLVVFIAAIYLGIRLLKMVYHITQYADIK 206
Query: 378 NFYNYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRK 437
FYN L I D DL W V Q++ ++ + + + K L+ D+ +R++R
Sbjct: 207 RFYNSALHIEDSDLDNFTWHEVQQRIRRVQAEQHMCID------KESLTELDIYHRVLRF 260
Query: 438 ENFVIALYDNNILDLSLPVPLL-RTCALTKTLEWNINLCIL---GFAFNEKGYLKQAFLR 493
+N+++AL + +L + +PL +L++ + +NI+ + G F L+ F
Sbjct: 261 KNYLVALMNKQLLPVRFHIPLYGEVVSLSRGMLFNIDFILFRGPGSPFQNNWQLRDEFAV 320
Query: 494 ESQREYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPI 553
S + L + L K + LN++L+P + + ++ F Y N + PG++G R ++
Sbjct: 321 RSNQTELAQRLSKLILGVALLNLVLAPVIFVWQLIYFSFSYANILRKEPGALGLRTWSNY 380
Query: 554 AEWKFREYNELYHIFQKRMRLSMIIADNYVNQFPNTLLSLTLSFIQFVSGSFVAILGILT 613
R +NEL H R+ + AD Y+N F + L ++ + F+SG + ++ L
Sbjct: 381 GRLYLRHFNELDHELDARLNRAYDYADRYLNSFSSPLAAVIAKNLLFISGGLLLLILALG 440
Query: 614 IFDPDNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTVLKPEETLEELVSYTHYAP 673
I++ F +L + G + VC + I DE V PE+ + ++++ HY P
Sbjct: 441 IYEEHVF------QVEHLLAILAGLGAIGVVCRTLIPDENLVWCPEQLMTAILAHVHYLP 494
Query: 674 KEWKGKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFRECT 733
EW+ + HT ++ EF + + LL E+ S +TPF+L F + ++ FFR T
Sbjct: 495 SEWRQQAHTTKVRQEFSNFFQFKAGYLLSEIFSPFVTPFVLIFVFRPKAIELVRFFRTFT 554
Query: 734 VYEEGLGYVCKYAMFEATKIDKG----TKAKKQTKRMFSQAEQDDSETESDEG 782
V G+G VC +A + K T ++ R +Q Q + + +S G
Sbjct: 555 VSVRGVGNVCSFAQMDVRKHGNPDWQLTSELEEMTRATAQQPQQEPQQQSLAG 607
>Hs13129082 [R] KOG2173 Integral membrane protein
Length = 446
Score = 187 bits (474), Expect = 8e-47
Identities = 119/387 (30%), Positives = 193/387 (49%), Gaps = 18/387 (4%)
Query: 396 WQSVIQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRKENFVIALYDNNILDLSLP 455
WQ V ++V + ++ I + K L+ D+ +RI+R +N+++AL + ++L L
Sbjct: 9 WQEVQARIVQTQKEHQICIH------KRELTELDIYHRILRFQNYMVALVNKSLLPLRFR 62
Query: 456 VPLLRTCAL-TKTLEWNINLCIL---GFAFNEKGYLKQAFLRESQREYLGEELKKRFVLA 511
+P L T+ L++N L + G F + LK + R QR L + L R +
Sbjct: 63 LPGLGEAVFFTRGLKYNFELILFWGPGSLFLNEWSLKAEYKRGGQRLELAQRLSNRILWI 122
Query: 512 GFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPIAEWKFREYNELYHIFQKR 571
G N +L P ++ + +L FF Y K PG++G+R ++ R +NEL H Q R
Sbjct: 123 GIANFLLCPLILIWQILYAFFSYAEVLKREPGALGARCWSLYGRCYLRHFNELEHELQSR 182
Query: 572 MRLSMIIADNYVNQFPNTLLSLTLSFIQFVSGSFVAILGILTIFDPDNFLNFEITPDRTV 631
+ A Y+N F + LL+L F +GS +A+L LTI+D D + V
Sbjct: 183 LNRGYKPASKYMNCFLSPLLTLLAKNGAFFAGSILAVLIALTIYDED------VLAVEHV 236
Query: 632 LFYMTVFGTLWAVCHSSINDEYTVLKPEETLEELVSYTHYAPKEWKGKYHTEDIKNEFCR 691
L +T+ G VC S I D++ V PE+ L ++++ HY P W+G H ++EF +
Sbjct: 237 LTTVTLLGVTVTVCRSFIPDQHMVFCPEQLLRVILAHIHYMPDHWQGNAHRSQTRDEFAQ 296
Query: 692 LYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFRECTVYEEGLGYVCKYAMFEAT 751
L+ + +L EL+S I+TP IL F L + IIDFFR TV G+G C +A +
Sbjct: 297 LFQYKAVFILEELLSPIVTPLILIFCLRPRALEIIDFFRNFTVEVVGVGDTCSFAQMDVR 356
Query: 752 K--IDKGTKAKKQTKRMFSQAEQDDSE 776
+ + A + ++ QAE +E
Sbjct: 357 QHGHPQWLSAGQTEASVYQQAEDGKTE 383
>CE20100 [R] KOG2173 Integral membrane protein
Length = 880
Score = 170 bits (430), Expect = 1e-41
Identities = 124/505 (24%), Positives = 224/505 (43%), Gaps = 61/505 (12%)
Query: 269 KWANIENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRLSSS 328
+W ++ NLD F +YEY+ G+ CI+ +KV L +FV+ +T+ C++Y L ++
Sbjct: 129 RWDHVLNLDEFFTHIYEYHQNGGYLCIVLQKVFSLLQFIFVMSFTTFFTQCVNYQFLFAN 188
Query: 329 HT-------------FEEIHIEQCYKTQISPTAKVFLWIFYAFIGLKVLQLYFDVK---- 371
F + ++ C A + +W+ +A + V + +K
Sbjct: 189 TNVTSHGTVNQGKRHFGDAVVDNC-------PAHISIWMIFAILAAIVYWITRVIKHAQY 241
Query: 372 --ALKDIRNFYNYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNRLSAHD 429
+ +I+ FY + L I+D L + W ++++++ E + K RLS H
Sbjct: 242 IMKMSEIQQFYAHELKIADDQLPNLTWHAIVKRIC-------------EAQKKLRLSIHQ 288
Query: 430 -------VANRIMRKENFVIALYDNNILDLSLPVPLLRTCA-LTKTLEWNINLCILGFAF 481
+ +RI+R +N++ + + IL VP L A L L+ I + F
Sbjct: 289 DNITSIYIYHRILRYKNYMTGMINKRILHPVFDVPFLGPIAYLPNNLKHEIERIL--FTS 346
Query: 482 NEKGYLKQAFLRESQREYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTS 541
+ + LRE + + ++ + + +N+ L ++ +Y
Sbjct: 347 STSAWTNGPNLREEYKHHEQLDMAAKKMKEDVINLFLQILRISVARPDASTAPIPDYGIV 406
Query: 542 PGSIGSRQYTPIAEWK------FREYNELYHIFQKRMRLSMIIADNYVNQFPNTLLSLTL 595
+ G+ + T W R +NEL H R+ S I A Y++QF + +L +
Sbjct: 407 LLTDGAHKKTTRWAWNEKIQYLLRHFNELDHELSARLNRSHIYAAAYMDQFFSPVLEIAA 466
Query: 596 SFIQFVSGSFVAILGILTIFDPDNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTV 655
I F++ + +L IL+ +D D + V+ +T+ G + VC I DE V
Sbjct: 467 KNITFIAAAVFGVLTILSAWDED------VLQVEHVITVLTICGIVVLVCRGMIPDENLV 520
Query: 656 LKPEETLEELVSYTHYAPKEWKGKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILW 715
+PE + + S HY P WKGK HT +++EF +L+ ++ + EL S I TPF+L
Sbjct: 521 WQPEILMTHVTSELHYLPSTWKGKAHTTGVRHEFDQLFQMKWMFFVLELTSPIFTPFVLL 580
Query: 716 FSLPKNSERIIDFFRECTVYEEGLG 740
F L ++ +FF + T +GLG
Sbjct: 581 FWLRPRCSQLANFFHDYTERVDGLG 605
>Hs20542893 [R] KOG2173 Integral membrane protein
Length = 804
Score = 145 bits (367), Expect = 2e-34
Identities = 131/500 (26%), Positives = 234/500 (46%), Gaps = 54/500 (10%)
Query: 283 VYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRL----SSSHT-----FEE 333
+Y Y+ NGF CI+ E V L +F+V +T++ C+DY+ L S+HT +
Sbjct: 154 IYSYHQRNGFACILLEDVFQLGQFIFIVTFTTFLLRCVDYNVLFANQPSNHTRPGPFHSK 213
Query: 334 IHIE-------QCYKTQ--ISPTAKVFLWIFYAFIGLKVLQL----YFDVKALKDIRNFY 380
+ + QC + + SPTA+ + + L +L + ++ V+ L+ + N +
Sbjct: 214 VTLSDAILPSAQCAERRPPFSPTARPTPYRIRSSPLLVLLLVLAAGFWLVQLLRSVCNLF 273
Query: 381 NYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNR-LSAHDVANRIMRKEN 439
+Y D+Q V ++ I + + + R L+ D+ +RI+R N
Sbjct: 274 SYW------DIQ-----------VFYREALHIPPRSGGLCVQPRPLTELDIHHRILRYTN 316
Query: 440 FVIALYDNNILDLSLPVPLLRTCA-LTKTLEWNINLCILG--FAFNEKGY-LKQAFLRES 495
+ +AL + +L P+P + A L++ L N++L + F+ G+ L A+ R
Sbjct: 317 YQVALANKGLLPARCPLPWGGSAAFLSRGLALNVDLLLFRGPFSLFRGGWELPHAYKRSD 376
Query: 496 QREYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPIAE 555
QR L + +L LN+ LSP ++ + VL F+ + + PG++G+R ++ +A
Sbjct: 377 QRGALAARWGRTVLLLAALNLALSPLVLAWQVLHVFYSHVELLRREPGALGARGWSRLAR 436
Query: 556 WKFREYNELYHIFQKRMRLSMIIADNYVNQF--PNTLLSLTLSFIQFVSGSFVAILGILT 613
+ R +NEL H + R+ + A ++ P L +L + F +G+ A L +LT
Sbjct: 437 LQLRHFNELPHELRARLARAYRPAAAFLRTAAPPAPLRTLLARQLVFFAGALFAALLVLT 496
Query: 614 IFDPDNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTVLK-PEETLEELVSYTHYA 672
++D D + VL MT G V S I +E + P+ L+ +++ HY
Sbjct: 497 VYDED------VLAVEHVLTAMTALGVTATVARSFIPEEQCQGRAPQLLLQTALAHMHYL 550
Query: 673 PKEWKGKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFREC 732
P+E G + + +L R LL EL+S ++TP L F + IIDFF
Sbjct: 551 PEE-PGPGGRDRAYRQMAQLLQYRAVSLLEELLSPLLTPLFLLFWFRPRALEIIDFFHHF 609
Query: 733 TVYEEGLGYVCKYAMFEATK 752
TV G+G +C +A+ + +
Sbjct: 610 TVDVAGVGDICSFALMDVKR 629
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,058,961
Number of Sequences: 60738
Number of extensions: 2140219
Number of successful extensions: 5865
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 5831
Number of HSP's gapped (non-prelim): 13
length of query: 908
length of database: 30,389,216
effective HSP length: 116
effective length of query: 792
effective length of database: 23,343,608
effective search space: 18488137536
effective search space used: 18488137536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)