ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4066 good B KOG3118 Chromatin structure and dynamics Disrupter of silencing SAS10
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4066 1435065 1436900 612
(612 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL153c [B] KOG3118 Disrupter of silencing SAS10 562 e-160
SPBC3B8.09 [B] KOG3118 Disrupter of silencing SAS10 210 4e-54
Hs9966799 [B] KOG3118 Disrupter of silencing SAS10 61 4e-09
>YDL153c [B] KOG3118 Disrupter of silencing SAS10
Length = 610
Score = 562 bits (1449), Expect = e-160
Identities = 302/612 (49%), Positives = 379/612 (61%), Gaps = 13/612 (2%)
Query: 10 KRGSNRRQDQE---EDVAYGMNEVDDFANKREKVLLEDAGLDQREPEDDFDLXXXXXXXX 66
++GSNR + E E YG+NEVDDFA+KREKVLL + +DD L
Sbjct: 3 RKGSNRTKTSEVGDEINPYGLNEVDDFASKREKVLLGQSTFGDSNKDDDHSLLEDEDEEE 62
Query: 67 XXXXXXXXXXXXXXXXXXXXXXXXLTGEAVYKKVFGRKLDVGENAEE-ESGTMLDNENAW 125
L G A YKK+FGR L+ + EE E MLDNENAW
Sbjct: 63 VLAMDEDDESIDEREDEEEEEEEELDGAAAYKKIFGRNLETDQLPEEDEENGMLDNENAW 122
Query: 126 GASKAEYYGADDLDDEETAREIEKEALRQQKKHLEDLHMEDYLEDEVDEEWVKEAKEFDL 185
G++K EYYGADDLDD+E A+EIEKEALRQQKKHLE+L+M DYL++E +EEWVK AKEFD+
Sbjct: 123 GSTKGEYYGADDLDDDEAAKEIEKEALRQQKKHLEELNMNDYLDEEEEEEWVKSAKEFDM 182
Query: 186 GQFKDQKDQERPTEISLRDVLNMDLERKEGFLKTSFPEYLPLSKEFSKLSPVLDELKLKQ 245
G+FK+ Q T+ S+ D+LNMD E ++ +L+T FPE+ PLSKEF++L+P DELK
Sbjct: 183 GEFKNSTKQ-ADTKTSITDILNMDDEARDNYLRTMFPEFAPLSKEFTELAPKFDELK--- 238
Query: 246 TEENNELIQIKIMALSSYLGTISSYFAVFLYELQNNEDFISMKDHPVMERILECKEIWRQ 305
E NE ++K++AL SYLGTIS Y+++ L+EL NNEDF SMK HPVME+IL KEIWRQ
Sbjct: 239 KSEENEFNKLKLIALGSYLGTISCYYSILLHELHNNEDFTSMKGHPVMEKILTTKEIWRQ 298
Query: 306 ASELPDTEAIRFEQDSDAEENISDIGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 365
ASELP + + S++EE +
Sbjct: 299 ASELPSSFDVNEGDGSESEETANIEAFNEKKLNELQNSEDSDAEDGGKQKQEIDEEERES 358
Query: 366 XXXXXXXNFDIE-----LSNRAANKVQKDRILQDVDDFVEDEIADVDVQEKKTRKKTLRF 420
+ DI+ ++ + K + + DDF+E EIADVD Q+KK R++TLRF
Sbjct: 359 DEEEEEEDVDIDDFEEYVAQSRLHSKPKTSSMPEADDFIESEIADVDAQDKKARRRTLRF 418
Query: 421 YTSKIDQKASKKTDRFKGDDDIPYKERLYERQQRLLEEARKRGLHDKNAADLNTDDINSD 480
YTSKIDQ+ +KKTDRFKGDDDIPYKERL+ERQQRLL+EARKRG+HD N ADL+ D S+
Sbjct: 419 YTSKIDQQENKKTDRFKGDDDIPYKERLFERQQRLLDEARKRGMHDNNGADLDDKDYGSE 478
Query: 481 DEKTAKDIKRDAENEYYKSIRADRQHKKDSRLQXXXXXXXXXXXXXXXXXXXXITEDGKR 540
DE ++ I EN+YY+ ++ +Q KK SR + ++ DGKR
Sbjct: 479 DEAVSRSINTQGENDYYQQVQRGKQDKKISRKEAHKNAVIAAREGKLAELAENVSGDGKR 538
Query: 541 AINYQILKNKGLTPRRKKDNRNSRVXXXXXXXXXXXXXXSVRAVYSGGQSGAYEGEKTGI 600
AINYQILKNKGLTP+R KDNRNSRV SVRAVYSGGQSG YEGEKTGI
Sbjct: 539 AINYQILKNKGLTPKRNKDNRNSRVKKRKKYQKAQKKLKSVRAVYSGGQSGVYEGEKTGI 598
Query: 601 KKNLTKSVKFKN 612
KK LT+SVKFKN
Sbjct: 599 KKGLTRSVKFKN 610
>SPBC3B8.09 [B] KOG3118 Disrupter of silencing SAS10
Length = 597
Score = 210 bits (535), Expect = 4e-54
Identities = 177/609 (29%), Positives = 277/609 (45%), Gaps = 64/609 (10%)
Query: 21 EDVAYGMNEVDDFANKREKVLLEDAGLDQREPEDDFDLXXXXXXXXXXXXXXXXXXXXXX 80
EDVA N D+F N ++K+L + D E D+ +L
Sbjct: 35 EDVA---NSEDEFYNAQDKILFD---ADNGEQADELELSDEELVALESSSDEEDGNAEEN 88
Query: 81 XXXXXXXXXXLTGEAVYKKVFGRKLDVGENAEEESGTMLDNENAWGASKAEYYGADDLDD 140
+++ G+K D N EE + DN+ WG S YYG DD D+
Sbjct: 89 LSEN-------------EELSGKKKDA-VNEEE----LYDNKG-WGRSAKSYYGGDDYDN 129
Query: 141 EE--------TAREIEKEALRQQKKHLEDLHMEDYLEDEVDEEWVKEAKEFDLGQFKDQK 192
E+ AR E+EALR Q+K LE + D ++D +W A DL K +
Sbjct: 130 EDYSEEDDEFDARMEEQEALRLQRKRLEKVSETDAIDDI--SQW---ADNSDLKSIK--Q 182
Query: 193 DQERPTEISLRDVLNMDLERKE--GFLKTSFPEYLPLSKEFSKLSPVLDELKLK-QTEEN 249
D L ++ DL R E L+ PE+ E ++L P L+E+K K +T +
Sbjct: 183 DSSAAAIEELVQQISPDLPRTELLKILEAKHPEFQLFLDELNQLKPQLNEIKEKLKTYPS 242
Query: 250 NELIQIKIMALSSYLGTISSYFAVFLYELQNNEDFISMKDHPVMERILECKEIWRQASEL 309
++L+Q + ALS+Y+ ++ YFA+ L++ E+ +K+HP+M ++ CK+ W L
Sbjct: 243 SQLLQAQCTALSTYISFLTFYFAL----LKDGEE--DLKNHPIMVDLVRCKQTWESYCGL 296
Query: 310 PDTEAIRFEQDSDAEENISDIGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 369
+ + EE+ I
Sbjct: 297 DEVLT-----PTSLEEDGKTIELHEKIASASDIGASEDEEDVDMHESISDNENEGIKDIP 351
Query: 370 XXXNFDIELSNRAANKVQKDRILQDVDDFVE-DEIADVDVQEKKTRKKTLRFYTSKIDQK 428
+ DI L RAA K + + ++++DD+ E + + DVD ++K RK++L+FY ++IDQK
Sbjct: 352 VAEDDDITLKFRAA-KSKINTNIKNLDDYGEGNRLDDVDAEDKIARKRSLKFYANQIDQK 410
Query: 429 ASKKTD---RFKGDDDIPYKERLYERQQRLLEEARKRGLHDKNAADLNTDDINSDD--EK 483
A+K++ GD D+PYKER +ERQQRL+ EA RG + ADL+ +D S
Sbjct: 411 AAKRSRAVLELSGDLDMPYKERRFERQQRLMREAAARGRNQDAGADLDDEDPESMGIPAN 470
Query: 484 TAKDIKRDAENEYYKSIRADRQHKKDSRLQXXXXXXXXXXXXXXXX-XXXXITEDGKRAI 542
++++ + +YY+S+ D++ K +L+ + E KR I
Sbjct: 471 VDREVEDQDDLDYYESL--DKKSKMAKKLRKENHDLERDLIRASRHPELIELGEGDKRGI 528
Query: 543 NYQILKNKGLTPRRKKDNRNSRVXXXXXXXXXXXXXXSVRAVYSGGQSGAYEGEKTGIKK 602
I KN+GLTPRR K+NRN R+ S +A+Y G G Y GE+TGIK
Sbjct: 529 TLDIAKNRGLTPRRPKENRNPRLKKRMRYEKAKKKLASKKAIYKGAPQGGYAGEQTGIKA 588
Query: 603 NLTKSVKFK 611
L KS+K +
Sbjct: 589 GLVKSIKLQ 597
>Hs9966799 [B] KOG3118 Disrupter of silencing SAS10
Length = 479
Score = 61.2 bits (147), Expect = 4e-09
Identities = 56/190 (29%), Positives = 80/190 (41%), Gaps = 23/190 (12%)
Query: 423 SKIDQKASKKTDRFKGDDDIPYKERLYERQQRLLEEARKRGLHDKNAADLNTDDINSDDE 482
S +DQK S + D K+ L + + + + + + +AA D++ D
Sbjct: 312 SVVDQKLSSEIRHLLTLKDDAVKKELIPKAKST--KPKPKSVSKTSAAACAVTDLSDDS- 368
Query: 483 KTAKDIKRDAENEYYKSIRADRQHKKDSRLQXXXXXXXXXXXXXXXXXXXXITEDGKRAI 542
D A+ +YYK I DRQ K + + ++ KRAI
Sbjct: 369 ----DFDEKAKLKYYKEIE-DRQKLKRKKEENSTEEQALED------------QNAKRAI 411
Query: 543 NYQILKNKGLTPRRKKDNRNSRV-XXXXXXXXXXXXXXSVRAVYSGGQSGAYEGEKTGIK 601
YQI KN+GLTPRRKK +RN RV VR V Q Y GE +GI+
Sbjct: 412 TYQIAKNRGLTPRRKKIDRNPRVKHREKFRRAKIRRRGQVREVRKEEQ--RYSGELSGIR 469
Query: 602 KNLTKSVKFK 611
+ KS+K K
Sbjct: 470 AGVKKSIKLK 479
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.310 0.131 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,918,996
Number of Sequences: 60738
Number of extensions: 1314257
Number of successful extensions: 6576
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 6556
Number of HSP's gapped (non-prelim): 9
length of query: 612
length of database: 30,389,216
effective HSP length: 112
effective length of query: 500
effective length of database: 23,586,560
effective search space: 11793280000
effective search space used: 11793280000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)