ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4075 check: MH L KOG0221 Replication, recombination and repair Mismatch repair ATPase MSH5 (MutS family)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4075 1439805 1437004 -934
(934 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL154w [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 590 e-168
Hs4505253 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 233 1e-60
Hs21361940 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 233 1e-60
CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 200 7e-51
YCR092c [L] KOG0218 Mismatch repair MSH3 179 2e-44
YOL090w [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 155 2e-37
At3g20475 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family) 155 2e-37
Hs4505249 [L] KOG0218 Mismatch repair MSH3 141 4e-33
YDR097c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 134 5e-31
Hs4557761 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 132 2e-30
SPAC8F11.03 [L] KOG0218 Mismatch repair MSH3 128 5e-29
CE21000 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 123 1e-27
ECU03g0540 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 123 2e-27
At4g02070 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 122 2e-27
CE28985 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 121 6e-27
Hs4504191 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 119 3e-26
7298155 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 114 5e-25
SPBC24C6.12c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 111 5e-24
SPCC285.16c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 111 6e-24
Hs20535615 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 111 6e-24
Hs4505251 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 109 2e-23
At4g25540 [L] KOG0218 Mismatch repair MSH3 105 3e-22
ECU10g0710 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 100 2e-20
CE24714 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 97 2e-19
YFL003c [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 95 4e-19
At4g17380 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family) 93 2e-18
At3g24320 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family) 82 4e-15
SPBC19G7.01c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family) 55 7e-07
>YDL154w [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 901
Score = 590 bits (1522), Expect = e-168
Identities = 347/905 (38%), Positives = 519/905 (57%), Gaps = 45/905 (4%)
Query: 55 SELIPGIGN---IQDSNATEIPAEGENRNVLEKYADETMHEQSINWENEVVFCLELQQSK 111
SE + IGN ++D A +GE +++ S +++ E+V C++ K
Sbjct: 10 SETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNREEDSSTIFSFDFDEEIVMCIDFSGGK 69
Query: 112 LGISLLDINQETLSVLNQDIIVNARSSXXXXXXXXXXXXXXXXXX----------PSVVL 161
LG S+LD + +TL +QD +VN + P+V L
Sbjct: 70 LGCSILDYHTKTLKAFDQDYVVNKTTISSHDLIDDADMSSNDISLLLGLLIMEANPTVCL 129
Query: 162 CSSRLGEVIYENLKFLSIERSFRLQMQSHDKFKVEYFVQHWNNFQESQQLIDIQGFQILD 221
+RL + I++ +K E + RL++Q +FK W+ Q S QL IL+
Sbjct: 130 VPARLEDWIFDYIKTKCDEINCRLELQPIKRFK------KWDLLQ-SLQLRGHDNQTILN 182
Query: 222 QLGTNK--AAKVTTMSLSCLIKSMDHFSAVDFDECE--------MFNFFEKV-NIVRQLM 270
+ +N VT ++ C++ + + + + N FE V + +R +
Sbjct: 183 DILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGIRYID 242
Query: 271 LKDRLFLDDDTLAALHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLAS 330
++DR+ LD++T++ALHIF GH ++ + G+ SVF+L N +S+ +R+LKSWL +
Sbjct: 243 IRDRMVLDENTISALHIFPTAHKLGHD-KMMRNGFFSVFELFNQVSSDYARRILKSWLIN 301
Query: 331 PLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNIFSIVNEMSKGAVKLSVWRKY 390
PL+NK IE R +IR+L+D +NAI+F DLS S+K P+ F +N++ G L W K
Sbjct: 302 PLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKSTLGTWSKV 361
Query: 391 ISFCTKTVEIINLIHILYDSSDNCRLFNTIKNDLDKSMMLKILKKTESVLDLEGSLNQDA 450
SF K + I L+ L SD + + IKN +D S + + L+K E+V+D + S +
Sbjct: 362 ASFLEKGIAIFQLVSSLKLGSDEANILHDIKNKVDISALKECLRKVETVIDFDTSRDTKT 421
Query: 451 IVIKDKVRIELDEARGTYFELEGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNALINA 510
+ I V LDE R Y LEG+L VA E L++T+ + K K L L+NA
Sbjct: 422 LTINTGVDNRLDECRNIYNHLEGILLDVARETQIFLLNTMPQEDCKTTKSLE---KLVNA 478
Query: 511 IYLPQLGYLLCVDASIEDMFDPAV-LYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIIS 569
+Y+PQLGYL+ + +E + D L W EIFR IY+KN +DE YGD++G IS
Sbjct: 479 VYIPQLGYLVTISVLMEPLLDGIPNLQWEEIFRSSENIYFKNGRVLELDETYGDIYGAIS 538
Query: 570 DXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFAKTAISQNYVQPXXXXXXXXXXX 629
D Q +L K + +ELE+L+SFA+ + +NY +P
Sbjct: 539 DFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVSAERNYAEPQLVEDECILEI 598
Query: 630 XNGRHPLYETLVDTYIPNDLRMLGGTFDNDTW-NNNFKRISVITGANASGKSVFLTQNGL 688
NGRH LYET +D YIPN + GG F +W N RI V+TGANASGKSV+LTQNGL
Sbjct: 599 INGRHALYETFLDNYIPNSTMIDGGLFSELSWCEQNKGRIIVVTGANASGKSVYLTQNGL 658
Query: 689 IVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSL 748
IV+LA IGCFVPA+ ARIG+ DKILTR+ T+E+V KTQS+F +D+ QM+K LSLAT +SL
Sbjct: 659 IVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSL 718
Query: 749 LLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFY 808
+LIDE+GKGTD++DG S+FG+I+ + S+S CPR+IA TH++E+F+ N+LT I G+ Y
Sbjct: 719 ILIDEYGKGTDILDGPSLFGSIMLNMSKSEKCPRIIACTHFHELFNENVLTENIKGIKHY 778
Query: 809 KTEILL----QVMEKENKGNARD-EMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRA 863
T+IL+ ++E + G + E ITFL+K+ GI+ SFGI+CAK CGL + IV+RA
Sbjct: 779 CTDILISQKYNLLETAHVGEDHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERA 838
Query: 864 QELTTQIADGFDIAKNYSKLTIEELNQFRIDQDIAKEFVAWDLDLESIHSDKIQHAIRRK 923
+EL+ I G D+ + LT +E+ +F+ +Q+I K+F++WDLDLE+ + + +R K
Sbjct: 839 EELSRMINRGDDVVQQCGNLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSE---NLRLK 895
Query: 924 LQRIL 928
L+ L
Sbjct: 896 LKNFL 900
>Hs4505253 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 834
Score = 233 bits (593), Expect = 1e-60
Identities = 190/661 (28%), Positives = 301/661 (44%), Gaps = 52/661 (7%)
Query: 253 ECEMFNFFEKVNIVRQLMLKDRLFLDDDTLAALHIFKPIQIPGHFCEIT--KTGYSSVFD 310
E E +N + ++ ML + +D DT + L IFK P + + K G S +F
Sbjct: 198 ELEDYNVSVPILGFKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLS-LFG 256
Query: 311 LLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNI 370
+LN + G++LL+ W P + + R VI+ + +N + L L ++ N+
Sbjct: 257 ILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNV 316
Query: 371 FSIVNEMSKGAVKLSVWRKYISFCTKTV-EIINLIHILYDSSDNCRLFNTIKNDLDKSMM 429
I+ M K+S W+ KTV + L + +LF I + +
Sbjct: 317 PLILKRMKLSHTKVSDWQVLY----KTVYSALGLRDACRSLPQSIQLFRDIAQEFSDDLH 372
Query: 430 LKILKKTESVLDLEGSLNQDAIVIKDKVRIELDEARGTYFELEGVLNLVANEANNTLIST 489
I V+D EGSL ++ + + E+DE + L L VA
Sbjct: 373 -HIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVAR--------- 422
Query: 490 LQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDA--SIEDMFDPAVLYWTEIFREQNVI 547
K + L+ R + IY+P +G+LL + S+ + D + +F + +
Sbjct: 423 ------KELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL 476
Query: 548 YYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFA 607
+Y++ TK +D GDLH I D Q VL + + L+VL++ A
Sbjct: 477 HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA 536
Query: 608 KTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNNFKR 667
A Y +P NGRHPL E T++PN G R
Sbjct: 537 SAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNSTECGGDK----------GR 586
Query: 668 ISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQS 727
+ VITG N+SGKS++L Q GLI F+A +G FVPA+ A IG VD I TR+ + ES++ S
Sbjct: 587 VKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLS 646
Query: 728 TFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDF-SRSSSCPRVIAS 786
TF ID NQ++K ++ AT +SL+LIDEFGKGT+ +DGL++ A+++ + +R +CP + +
Sbjct: 647 TFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVA 706
Query: 787 THYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSFG 846
T++ + +L +V Y T ME GN + F Y++ G+A S
Sbjct: 707 TNFLSLVQLQLLPQ--GPLVQYLT------METCEDGND----LVFFYQVCEGVAKASHA 754
Query: 847 IFCAKNCGLRQSIVQRAQELTTQIADGFDIAKNYSKLTIEELNQFRIDQDIAKEFVAWDL 906
A GL +V R +E++ I G I L + NQ Q + +F+ DL
Sbjct: 755 SHTAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLL---KKNQMENCQTLVDKFMKLDL 811
Query: 907 D 907
+
Sbjct: 812 E 812
>Hs21361940 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 851
Score = 233 bits (593), Expect = 1e-60
Identities = 191/661 (28%), Positives = 301/661 (44%), Gaps = 52/661 (7%)
Query: 253 ECEMFNFFEKVNIVRQLMLKDRLFLDDDTLAALHIFKPIQIPGHFCEIT--KTGYSSVFD 310
E E +N + ++ ML + +D DT + L IFK P + + K G S +F
Sbjct: 215 ELEDYNVSVPILGFKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLS-LFG 273
Query: 311 LLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNI 370
+LN + G++LL+ W P + + R VI+ + +N + L L ++ N+
Sbjct: 274 ILNRCHCKWGEKLLRLWFTRPTHDLGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNV 333
Query: 371 FSIVNEMSKGAVKLSVWRKYISFCTKTV-EIINLIHILYDSSDNCRLFNTIKNDLDKSMM 429
I+ M K+S W+ KTV + L + +LF I + +
Sbjct: 334 PLILKRMKLSHTKVSDWQVLY----KTVYSALGLRDACRSLPQSIQLFRDIAQEFSDDLH 389
Query: 430 LKILKKTESVLDLEGSLNQDAIVIKDKVRIELDEARGTYFELEGVLNLVANEANNTLIST 489
I V+D EGSL ++ + + E+DE + L L VA
Sbjct: 390 -HIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEVAR--------- 439
Query: 490 LQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDA--SIEDMFDPAVLYWTEIFREQNVI 547
K + L+ R + IY+P +G+LL + S+ + D + +F + +
Sbjct: 440 ------KELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL 493
Query: 548 YYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFA 607
+Y++ TK +D GDLH I D Q VL + + L+VL++ A
Sbjct: 494 HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALA 553
Query: 608 KTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNNFKR 667
A Y +P NGRHPL E T++PN G R
Sbjct: 554 SAARDYGYSRPRYSPQVLGVRIQNGRHPLMELCARTFVPNSTECGGDK----------GR 603
Query: 668 ISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQS 727
+ VITG N+SGKS++L Q GLI F+A +G FVPA+ A IG VD I TR+ + ES++ S
Sbjct: 604 VKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLS 663
Query: 728 TFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDF-SRSSSCPRVIAS 786
TF ID NQ++K ++ AT +SL+LIDEFGKGT+ +DGL++ A+++ + +R +CP V +
Sbjct: 664 TFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPTVFVA 723
Query: 787 THYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSFG 846
T++ + +L +V Y T ME GN + F Y++ G+A S
Sbjct: 724 TNFLSLVQLQLLPQ--GPLVQYLT------METCEDGND----LVFFYQVCEGVAKASHA 771
Query: 847 IFCAKNCGLRQSIVQRAQELTTQIADGFDIAKNYSKLTIEELNQFRIDQDIAKEFVAWDL 906
A GL +V R +E++ I G I L + NQ Q + +F+ DL
Sbjct: 772 SHTAAQAGLPDKLVARGKEVSDLIRSGKPIKPVKDLL---KKNQMENCQTLVDKFMKLDL 828
Query: 907 D 907
+
Sbjct: 829 E 829
>CE26678 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 1369
Score = 200 bits (509), Expect = 7e-51
Identities = 158/603 (26%), Positives = 284/603 (46%), Gaps = 62/603 (10%)
Query: 307 SVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKY 366
S++ L++ S +GK+ L+ W +P +++ + RQK + NA + LS+ L
Sbjct: 306 SLYQLMDKCRSTVGKKCLRKWFRNPTTDRDDLVSRQKCVHYFKQDWNAEVTAKLSSILGR 365
Query: 367 MPNIFSIVNEMSKGAVKLSVWRKYISFCTKTVEIINLIHILYDSSDNCRLFNTIKNDLDK 426
+ + S+ + G +L W ++S VEI+N+I S + +++DL +
Sbjct: 366 VKALNSVFQKFQSGTAQLIHWECFVSTVNALVEILNIIRQTPISKEF-----PVESDLLR 420
Query: 427 SMMLKILKKTESVLDLEGSLNQDAIVIKDKVRIELDEARGTYFELEGVLNLVANEANNTL 486
+ +I S+++ S Q + + + + ELDE R TY + VL +A + L
Sbjct: 421 EVS-EIAVIAGSIINFAESKIQGRVTVMNGIDEELDEIRDTYENMPMVLTAIAKQEEARL 479
Query: 487 ISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCV--DASIEDMFDPAVLYWTEIFREQ 544
SN + +Y+P +G++L V D +E D +LY T
Sbjct: 480 GLPPYSN--------------VACVYIPLVGFVLSVPRDYGVESQPDMTLLYSTH----- 520
Query: 545 NVIYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLV 604
+ +N T +D+ +GD+ + D + V+ K +I+ + ++VL+
Sbjct: 521 EDLRVRNATTSRLDDEFGDILMRLIDSQTAIILTLKTRVMKKKRSIIKLLSIASRIDVLI 580
Query: 605 SFAKTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNN 664
SF A + P P+ E V+ Y P + ++ +F + ++
Sbjct: 581 SFGLIAAQNGWNCPALVD-----------EPVIEA-VELYHPISVLVVKKSFVPNQVSSG 628
Query: 665 FKRI--SVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESV 722
I S+ITG NA GKSV++ G++VFL+HIG FVPA +A+IG+VD+I+TR+ T +SV
Sbjct: 629 RDGIKASIITGPNACGKSVYMKSIGIMVFLSHIGSFVPARHAKIGIVDRIVTRMFTVDSV 688
Query: 723 AKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSR--SSSC 780
STF D Q++ L AT SL++IDEFGKGT GLS+ +++ + + C
Sbjct: 689 LDGMSTFAKDVEQVALALRKATGNSLVIIDEFGKGTMTEVGLSLLASVMTYWMNRGADRC 748
Query: 781 PRVIASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGI 840
P + S+H++ + PN + E N F +L + K I +L++++ G+
Sbjct: 749 PHIFLSSHFHAL--PNYIPLETNIATFLTFTVLREAGGK----------IKYLFRMTPGL 796
Query: 841 ATNSFGIFCAKNCGLRQSIVQRAQELTTQIADG-------FDIAKNYSKLTIEELNQFRI 893
SF + AK G+ ++ RA + + G +++ + K +E+++
Sbjct: 797 VDCSFALSVAKEEGIPPPVIGRACRIYKALKAGTLLKEIKAEVSNDNEKQLVEDMDVVLA 856
Query: 894 DQD 896
D+D
Sbjct: 857 DED 859
>YCR092c [L] KOG0218 Mismatch repair MSH3
Length = 1047
Score = 179 bits (454), Expect = 2e-44
Identities = 159/621 (25%), Positives = 280/621 (44%), Gaps = 79/621 (12%)
Query: 272 KDRLFLDDDTLAALHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASP 331
K + LD ++L +L IF G S+F LL+HT + G R+L+ W+ P
Sbjct: 444 KIHMLLDPNSLQSLDIFTH-----------DGGKGSLFWLLDHTRTSFGLRMLREWILKP 492
Query: 332 LSNKILIEERQKVIRSLIDG-KNAILFDDLSNSLKYMPNIFSIVNEMSKGAVKLSVWRKY 390
L + IEER I + N+I F+ L+ L + P++ +N + G Y
Sbjct: 493 LVDVHQIEERLDAIECITSEINNSIFFESLNQMLNHTPDLLRTLNRIMYGTTSRKEVYFY 552
Query: 391 ISFCTKTVEIINL----IHILYDSSDN---------CRLFNTIKNDLDKSMMLKILKKTE 437
+ T V+ + + + SSD RLF+ + L + + L
Sbjct: 553 LKQITSFVDHFKMHQSYLSEHFKSSDGRIGKQSPLLFRLFSELNELLSTTQLPHFLTM-- 610
Query: 438 SVLDLEGSLNQDAIVIKDKVRIELDEARGTYFEL-EGVLNLVANEANNTLISTLQSNEEK 496
+N A++ K+ + +D ++ EG++ + + ++ S L+ +
Sbjct: 611 --------INVSAVMEKNSDKQVMDFFNLNNYDCSEGIIKI--QRESESVRSQLKEELAE 660
Query: 497 LFKKLNGRNALINAIYLPQLGYLLCV-DASIEDMFDPAVLYWTEIFREQNVIYYKNDDTK 555
+ K L + +N + ++ YL+ V ++ I+D+ D W ++ + V + T+
Sbjct: 661 IRKYL--KRPYLN--FRDEVDYLIEVKNSQIKDLPDD----WIKVNNTKMVSRFTTPRTQ 712
Query: 556 VMD---EHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFAKTAIS 612
+ E+Y DL S+ A I L+ A+ + ++S A T+ +
Sbjct: 713 KLTQKLEYYKDLLIRESELQYKEFLNKITAEYTELRKITLN---LAQYDCILSLAATSCN 769
Query: 613 QNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVIT 672
NYV+P N R+P+ E+L Y+PND+ M + +I++IT
Sbjct: 770 VNYVRPTFVNGQQAIIAKNARNPIIESLDVHYVPNDIMM----------SPENGKINIIT 819
Query: 673 GANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEID 732
G N GKS ++ Q L+ +A IG FVPA+ R+ + + +LTR+ + + STF+++
Sbjct: 820 GPNMGGKSSYIRQVALLTIMAQIGSFVPAEEIRLSIFENVLTRIGAHDDIINGDSTFKVE 879
Query: 733 ANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHY--- 789
+ L RSLLL+DE G+GT DG+++ A+IK FS S CP ++ +TH+
Sbjct: 880 MLDILHILKNCNKRSLLLLDEVGRGTGTHDGIAISYALIKYFSELSDCPLILFTTHFPML 939
Query: 790 NEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIFC 849
E+ SP I ++ V +E K + FLYKL G+ NS+G+
Sbjct: 940 GEIKSPLIRNYHMDYV-------------EEQKTGEDWMSVIFLYKLKKGLTYNSYGMNV 986
Query: 850 AKNCGLRQSIVQRAQELTTQI 870
AK L + I+ RA ++ ++
Sbjct: 987 AKLARLDKDIINRAFSISEEL 1007
>YOL090w [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 964
Score = 155 bits (393), Expect = 2e-37
Identities = 178/695 (25%), Positives = 305/695 (43%), Gaps = 77/695 (11%)
Query: 271 LKDRLFLDDDTLAALHIF-KPIQIPGHFCEITKTGYSS---------VFDLLNHTTSELG 320
LK+ + LD + AL++F + Q P + +G++S +F LLNH + G
Sbjct: 291 LKEFMKLDASAIKALNLFPQGPQNPFGSNNLAVSGFTSAGNSGKVTSLFQLLNHCKTNAG 350
Query: 321 KRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNIFSIVNEMSKG 380
RLL WL PL+N I +R ++ LID + + S L +P+I + +++K
Sbjct: 351 VRLLNEWLKQPLTNIDEINKRHDLVDYLID-QIELRQMLTSEYLPMIPDIRRLTKKLNKR 409
Query: 381 AVKLSVWRKYISFCTKTVEIINLI-HILYDSSDNCRLFNTIKNDLDKSMML--------- 430
V + Y F + EI+ + L D S + N+L +S+ L
Sbjct: 410 GNLEDVLKIY-QFSKRIPEIVQVFTSFLEDDSPTEPV-----NELVRSVWLAPLSHHVEP 463
Query: 431 --KILKKTESVLDLEGSLNQDAIVIKDKVRIELDEARGTYFELEGVLNLVANEANNTLIS 488
K + E+ +DL+ + +IK +E +E G ++ L+ + +E ++ +
Sbjct: 464 LSKFEEMVETTVDLDAYEENNEFMIK----VEFNEELG---KIRSKLDTLRDEIHSIHLD 516
Query: 489 TLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIEDMFDPAV-LYWTEIFREQNVI 547
+ + KKL N ++ C+ + D + + E+ + I
Sbjct: 517 SAEDLGFDPDKKLKLENHHLHG---------WCMRLTRNDAKELRKHKKYIELSTVKAGI 567
Query: 548 YYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFA 607
++ K + L N L P A L+V+ SFA
Sbjct: 568 FFSTKQLKSIANETNILQKEYDKQQSALVREIINITLTYTPVFEKLSLVLAHLDVIASFA 627
Query: 608 KTAISQN--YVQPXXX--XXXXXXXXXNGRHPLYETLVD-TYIPNDLRMLGGTFDNDTWN 662
T+ Y++P + RHP+ E D ++I ND+ + G D
Sbjct: 628 HTSSYAPIPYIRPKLHPMDSERRTHLISSRHPVLEMQDDISFISNDVTLESGKGD----- 682
Query: 663 NNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESV 722
+ITG N GKS ++ Q G+I +A IGCFVP + A I +VD IL RV +S
Sbjct: 683 -----FLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVGAGDSQ 737
Query: 723 AKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPR 782
K STF ++ + + L A+ SL+++DE G+GT DG + AI + + C
Sbjct: 738 LKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIASKIGCFA 797
Query: 783 VIASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIAT 842
+ A TH++E+ L+ ++ V ++ KE K + DE IT LYK+ GI+
Sbjct: 798 LFA-THFHELTE---LSEKLPNVKNMHVVAHIEKNLKEQKHD--DEDITLLYKVEPGISD 851
Query: 843 NSFGIFCAKNCGLRQSIVQRAQELTTQIAD----GFDIAKNYSKLTIEELNQFRID-QDI 897
SFGI A+ + IV+ A+ ++ D D+ K +KL+++E+N+ I + +
Sbjct: 852 QSFGIHVAEVVQFPEKIVKMAKRKANELDDLKTNNEDLKK--AKLSLQEVNEGNIRLKAL 909
Query: 898 AKEFVAWDLDLESIH--SDKIQHAIRRKLQRILDA 930
KE++ + E +H S + A + K+Q +L A
Sbjct: 910 LKEWIR-KVKEEGLHDPSKITEEASQHKIQELLRA 943
>At3g20475 [L] KOG0221 Mismatch repair ATPase MSH5 (MutS family)
Length = 321
Score = 155 bits (393), Expect = 2e-37
Identities = 108/307 (35%), Positives = 156/307 (50%), Gaps = 27/307 (8%)
Query: 610 AISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNNFKRIS 669
A NYV+P NGRH L E VDT+IPND + N+ RI
Sbjct: 31 AHQNNYVRPVLTVESLLDIR-NGRHVLQEMAVDTFIPNDTEI-----------NDNGRIH 78
Query: 670 VITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTF 729
+ITG N SGKS+++ Q LIVFL+HIG FVPAD A +GL D+I + ++ A+ QSTF
Sbjct: 79 IITGPNYSGKSIYVKQVALIVFLSHIGSFVPADAATVGLTDRIFCAMGSKFMTAE-QSTF 137
Query: 730 EIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHY 789
ID +Q+ L AT RSL L+DEFGKGT DG+ + G I F+ + PRV+ TH
Sbjct: 138 MIDLHQVGMMLRQATSRSLCLLDEFGKGTLTEDGIGLLGGTISHFATCAEPPRVVVCTHL 197
Query: 790 NEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIAT--NSFGI 847
E+ + + L + FY +L E N E I FLY+ + +
Sbjct: 198 TELLNESCLPVS-EKIKFYTMSVLRPDTESANM-----EEIVFLYRYGVSLTSILPKLPT 251
Query: 848 FCAKNCGLRQSIVQRAQELTTQIADGFDIAKNYSKLTIEEL-NQFRIDQDIAKEFVAWDL 906
F C + + +V+RA + D F+ N KL+++++ +Q + +D +F D+
Sbjct: 252 FLRLPC-VPEEVVKRA----AIVLDAFESNNNVDKLSLDKISSQDQAFKDAVDKFAELDI 306
Query: 907 DLESIHS 913
IH+
Sbjct: 307 SKGDIHA 313
>Hs4505249 [L] KOG0218 Mismatch repair MSH3
Length = 1128
Score = 141 bits (356), Expect = 4e-33
Identities = 157/704 (22%), Positives = 300/704 (42%), Gaps = 81/704 (11%)
Query: 184 RLQMQSHDKFKVEYFVQHWNNFQESQQLIDIQGFQILDQLGTNKAAKVTTMSLSCLIKSM 243
R++ + F+ + Q F ++ +DI+G QI+ G K SL+ +IK +
Sbjct: 445 RVERMDNIYFEYSHAFQAVTEFY-AKDTVDIKGSQIIS--GIVNLEKPVICSLAAIIKYL 501
Query: 244 DHFSAVDFDECEMFNFFEKVNIVRQLMLK-DRLFLDDDTLAALHIFKPIQIPGHFCEITK 302
F+ + K +QL K + + ++ TL L I + +
Sbjct: 502 KEFN--------LEKMLSKPENFKQLSSKMEFMTINGTTLRNLEILQN--------QTDM 545
Query: 303 TGYSSVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSN 362
S+ +L+HT + G+R LK W+ PL I R + ++ ++++ F + N
Sbjct: 546 KTKGSLLWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSESSV-FGQIEN 604
Query: 363 SLKYMPNIFSIVNEMSKGAVKLSVWRKYISFCTKTVEIINLIHILYDSSDNCRLF----- 417
L+ +P+I +G S++ K S T E ++ LY +
Sbjct: 605 HLRKLPDI-------ERGLC--SIYHKKCS----TQEFFLIVKTLYHLKSEFQAIIPAVN 651
Query: 418 NTIKNDLDKSMMLKILKKTESVLDLEGSLNQDAIVIKDKVRIELDEA-----RGTYFELE 472
+ I++DL ++++L+I + V LN+ A + DK + D + + E++
Sbjct: 652 SHIQSDLLRTVILEIPELLSPVEHYLKILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQ 711
Query: 473 GVLNLVANEANNTLISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIEDMFDP 532
GV++ + I + N + ++G+ +I + + C+
Sbjct: 712 GVIDEIRMHLQE--IRKILKNPSAQYVTVSGQEFMIEI----KNSAVSCIPTD------- 758
Query: 533 AVLYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILL 592
W ++ + V + + H L + ++
Sbjct: 759 ----WVKVGSTKAVSRFHSPFIVENYRHLNQLREQLVLDCSAEWLDFLEKFSEHYHSLCK 814
Query: 593 SGKCFAELEVLVSFAKTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLV---DTYIPNDL 649
+ A ++ + S AK A +Y +P NGRHP+ + L+ D Y+PN
Sbjct: 815 AVHHLATVDCIFSLAKVAKQGDYCRPTVQEERKIVIK-NGRHPVIDVLLGEQDQYVPN-- 871
Query: 650 RMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLV 709
N + + +R+ +ITG N GKS ++ Q LI +A IG +VPA+ A IG+V
Sbjct: 872 --------NTDLSEDSERVMIITGPNMGGKSSYIKQVALITIMAQIGSYVPAEEATIGIV 923
Query: 710 DKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGA 769
D I TR+ +++ K +STF + ++ + AT +SL+++DE G+GT DG+++ A
Sbjct: 924 DGIFTRMGAADNIYKGRSTFMEELTDTAEIIRKATSQSLVILDELGRGTSTHDGIAIAYA 983
Query: 770 IIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEM 829
++ F R + THY V + + + V Y L+ E + A +++
Sbjct: 984 TLEYFIRDVKSLTLFV-THYPPVC--ELEKNYSHQVGNYHMGFLVSEDESKLDPGAAEQV 1040
Query: 830 ---ITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
+TFLY+++ GIA S+G+ AK + I+++A + ++
Sbjct: 1041 PDFVTFLYQITRGIAARSYGLNVAKLADVPGEILKKAAHKSKEL 1084
>YDR097c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1242
Score = 134 bits (338), Expect = 5e-31
Identities = 142/637 (22%), Positives = 273/637 (42%), Gaps = 101/637 (15%)
Query: 275 LFLDDDTLAALHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASPLSN 334
+ LD TL L IF + ++F L N + +GKR++K WL PL
Sbjct: 614 MVLDGITLQNLEIFSN--------SFDGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLR 665
Query: 335 KILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNIFSIVNEMSKGAVKLSVWRKYISFC 394
K IE R + SL+ ++ L + L + +P++ ++ + +K+ + K I+
Sbjct: 666 KNDIESRLDSVDSLL--QDITLREQLEITFSKLPDLERMLARIHSRTIKVKDFEKVITAF 723
Query: 395 TKTVEIINLIHILYDSSDNCRLFNTIKNDLDKSM------MLKILKKTESVLDLEGSLNQ 448
+E L DS N N +K D+ K + +++ +K + + + ++N+
Sbjct: 724 ETIIE-------LQDSLKN----NDLKGDVSKYISSFPEGLVEAVKSWTNAFERQKAINE 772
Query: 449 DAIVIKDKVRIELDEARGTYFEL-EGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNAL 507
+ IV + IE D++ EL + ++ ++ S +Q + +G+
Sbjct: 773 NIIVPQRGFDIEFDKSMDRIQELEDELMEILMTYRKQFKCSNIQYKD-------SGKE-- 823
Query: 508 INAIYLPQLGYLLCVDASIEDMFDPAVLYWTEIFREQNVIYYKNDDTKVMDEHYGD---L 564
I I +P + ++ W ++ + Y +D+ + + + +
Sbjct: 824 IYTIEIP-----ISATKNVPSN-------WVQMAANKTYKRYYSDEVRALARSMAEAKEI 871
Query: 565 HGIISDXXXXXXXXXQNAVLNT--KPAILLSGKCFAELEVLVSFAKTA--ISQNYVQPXX 620
H + + +A NT P I + + ++ L++ +T+ + +P
Sbjct: 872 HKTLEEDLKNRLCQKFDAHYNTIWMPTI----QAISNIDCLLAITRTSEYLGAPSCRPTI 927
Query: 621 XXXXXXXXXX--NG-------RHPLYE---TLVDTYIPNDLRMLGGTFDNDTWNNNFKRI 668
NG RHP + T +IPND+ + R+
Sbjct: 928 VDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIEL----------GKEQPRL 977
Query: 669 SVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQST 728
++TGANA+GKS L + V +A +GC+VP ++A + +D+I+TR+ +++ + +ST
Sbjct: 978 GLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGKST 1037
Query: 729 FEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTH 788
F ++ + K L +AT RSLL++DE G+G DG ++ +++ + A TH
Sbjct: 1038 FFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFA-TH 1096
Query: 789 YNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIF 848
Y + S ++ + K IL+ + +TFLYK+ G + SFG+
Sbjct: 1097 YGTLASSFKHHPQVRPL---KMSILVDEATRN---------VTFLYKMLEGQSEGSFGMH 1144
Query: 849 CAKNCGLRQSIVQRAQ------ELTTQIADGFDIAKN 879
A CG+ + I+ AQ E T+++ D+A N
Sbjct: 1145 VASMCGISKEIIDNAQIAADNLEHTSRLVKERDLAAN 1181
>Hs4557761 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 934
Score = 132 bits (332), Expect = 2e-30
Identities = 166/690 (24%), Positives = 285/690 (41%), Gaps = 80/690 (11%)
Query: 230 KVTTMSLSCLIKSMDHFSAVDFDECEMFNFFEKVNIVRQLMLKDRLFLDDDTLAALHIFK 289
+V SLS +IK ++ S + F FE +K LD + AL++F+
Sbjct: 264 QVAVSSLSAVIKFLELLS-----DDSNFGQFELTTFDFSQYMK----LDIAAVRALNLFQ 314
Query: 290 PIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLI 349
E T TG S+ LLN + G+RL+ W+ PL +K IEER ++ + +
Sbjct: 315 GS------VEDT-TGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFV 367
Query: 350 DGKNA--ILFDDLSNSLKYMPNIFSIVNEMSKGAVKLSVWRKYISFCTKTVEIINLIHIL 407
+ L +DL L+ P++ + + + A L + + +I +
Sbjct: 368 EDAELRQTLQEDL---LRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKH 424
Query: 408 YDSSDNCRL--FNTIKNDLDKSMMLKILKKTESVLDLEGSLNQDAIVIKDKVRIELDEAR 465
L F T DL +S K + E+ LD++ N + +V K L E R
Sbjct: 425 EGKHQKLLLAVFVTPLTDL-RSDFSKFQEMIETTLDMDQVENHEFLV-KPSFDPNLSELR 482
Query: 466 GTYFELEGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDAS 525
++N + + +TLIS + K++ ++ Q GY V
Sbjct: 483 E-------IMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSA-------QFGYYFRVTCK 528
Query: 526 IEDMFDPAVLYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLN 585
E + + T + ++N + + N ++E Y + N
Sbjct: 529 EEKVLRNNKNFST-VDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSG 587
Query: 586 TKPAILLSGKCFAELEVLVSFAKTAISQN--YVQPXXXXXXXXXXXXNG-RHPLYETLVD 642
+ A+L+ +VSFA + YV+P RH E +
Sbjct: 588 YVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDE 647
Query: 643 -TYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPA 701
+IPND+ F+ D + +ITG N GKS ++ Q G+IV +A IGCFVP
Sbjct: 648 IAFIPNDVY-----FEKDK-----QMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPC 697
Query: 702 DNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVI 761
++A + +VD IL RV +S K STF + + + L AT SL++IDE G+GT
Sbjct: 698 ESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTY 757
Query: 762 DGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKEN 821
DG + A I ++ + + +TH++E+ L ++I V L
Sbjct: 758 DGFGLAWA-ISEYIATKIGAFCMFATHFHEL---TALANQIPTVNNLHVTAL-------- 805
Query: 822 KGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI--------ADG 873
+E +T LY++ G+ SFGI A+ + +++ A++ ++ + G
Sbjct: 806 ---TTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQG 862
Query: 874 FDIAKNYSKLTIEELNQFRIDQDIAKEFVA 903
+DI + +K E Q + I +EF++
Sbjct: 863 YDIMEPAAKKCYLEREQ---GEKIIQEFLS 889
>SPAC8F11.03 [L] KOG0218 Mismatch repair MSH3
Length = 1004
Score = 128 bits (321), Expect = 5e-29
Identities = 160/682 (23%), Positives = 292/682 (42%), Gaps = 113/682 (16%)
Query: 222 QLGTNKAAKVTTMSLSCLIKSMDHFSAVDFDECEMF---NFFEKVNIVRQLMLKDRLFLD 278
+L K + ++S+ CL ++ + ++F ++F NF++ + + ++L +
Sbjct: 354 ELHMEKVKSLHSLSIICLDMAISYL--MEFSLEDLFVASNFYQPFDSISSMVLSKQ---- 407
Query: 279 DDTLAALHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASPLSNKILI 338
L L +F + T S+F +L+ T + G+R+L+ WL PL +K I
Sbjct: 408 --ALEGLELFVN--------QTDHTPVGSLFWVLDRTYTRFGQRMLQRWLQKPLVDKENI 457
Query: 339 EERQKVIRSLIDGKNAIL---------FDDLSNSLKYM-------PNIFSIVNEMSKGAV 382
ER + L N+ + DL L + +F ++ K A
Sbjct: 458 IERLDAVEELAFNSNSQVQAIRKMLYRLPDLEKGLSRIYYQRCTPSEMFHVLKGFYKAA- 516
Query: 383 KLSVWRKYISFCTKTVEIINLIHILYDSS----------DNCRLFNTIKNDLDKSMMLKI 432
S + K C K+ + LI L S D N K D+ K +
Sbjct: 517 --SAFSKNSYSCFKSALLRRLIQQLPSISSIIDHFLGMFDQKEAENNNKVDMFKDIDNFD 574
Query: 433 LKKTESVLDLE-----GSLNQDAIVIKDKVRIELDEARGTYFELEGV-LNLVANEANNTL 486
L + + +D E L ++++ ++ L E R Y E + ++ N
Sbjct: 575 LSEEPNDVDYELAQEIRELKMSILMVRTEMDFHLQELRD-YLEYPNLEFSIWGNVKFCIE 633
Query: 487 ISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIEDMFDPAVLYWTEIFREQNV 546
+S + KL+ +L + P++ LL +S E+ I E+
Sbjct: 634 VSKGCKKIPPDWIKLSSTRSLFR-FHTPKIQSLLIELSSHEENLT--------ISSEK-- 682
Query: 547 IYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSF 606
Y++ +++ EHY +L + + VL T L+ L+SF
Sbjct: 683 -IYRSFLSRI-SEHYNELRNVTT-------------VLGT-------------LDCLISF 714
Query: 607 AKTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVD-TYIPNDLRMLGGTFDNDTWNNNF 665
A+ + Y +P RHP+ E L D +++PN + + +++
Sbjct: 715 ARISSQSGYTRPEFSDKELLIH--ESRHPMIELLSDKSFVPNHIHL----------SSDG 762
Query: 666 KRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKT 725
R +ITG N GKS F+ Q L +A GCFVPA +A + + D IL R+ + ++++
Sbjct: 763 VRCLLITGPNMGGKSSFVKQLALSAIMAQSGCFVPAKSALLPIFDSILIRMGSSDNLSVN 822
Query: 726 QSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIA 785
STF ++ + + LS AT +S+++IDE G+GT IDG ++ A++ ++ ++
Sbjct: 823 MSTFMVEMLETKEVLSKATEKSMVIIDELGRGTSTIDGEAISYAVLHYLNQYIK-SYLLF 881
Query: 786 STHYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSF 845
TH+ S IL G + + + + KE+ + + I+FLYKL G+A+ S+
Sbjct: 882 VTHFP---SLGILERRFEGQL--RCFHMGYLKSKEDFETSVSQSISFLYKLVPGVASKSY 936
Query: 846 GIFCAKNCGLRQSIVQRAQELT 867
G+ A+ G+ SI+ RA E++
Sbjct: 937 GLNVARMAGIPFSILSRATEIS 958
>CE21000 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 849
Score = 123 bits (309), Expect = 1e-27
Identities = 144/601 (23%), Positives = 251/601 (40%), Gaps = 64/601 (10%)
Query: 275 LFLDDDTLAALHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASPLSN 334
+ +D + AL +F Q+ ++ E K+ +++++LN + G++LL+ WL+ PL
Sbjct: 271 MLIDSCAVEALELF---QLNYNYLE--KSNNLTLYNVLNKCKTLPGEKLLRDWLSRPLCQ 325
Query: 335 KILIEERQKVIRSLIDGKNAILFDDLSNS-LKYMPNIFSIVNEMSKGAVKLSVWRKYISF 393
I ER ++ +L + N + L +S L MP+ + + + + R Y
Sbjct: 326 IDHINERLDIVEALFE--NQTIRQKLRDSILARMPDCSQLARRLMRKCTLQDLNRFY--- 380
Query: 394 CTKTVEIINLIHILYDSSDNCRLFNTIKNDLDKSMMLKILKKTESVLDL-EGSLNQDAIV 452
+ ++ + + F N L KS + +ILKK E L + + D
Sbjct: 381 --QAATLLETVEMQLIQLSEAEQFAPSINRLLKSEITEILKKVERFQVLCDEFFDFDYEK 438
Query: 453 IKDKVRIELD---EARGTYFELEGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNALIN 509
++R+ +D E + +LE + VA + + + + KL K
Sbjct: 439 ENKEIRVRVDFVPEIQEISEKLEQ-MERVAEKLRKKYSAKFECDNLKLDKN--------- 488
Query: 510 AIYLPQLGYLLCVDASIEDMFDPAVLYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIIS 569
Q G+ V E ++ E + V + + + + DE + + H +
Sbjct: 489 ----SQYGFYFRVTLKEEKSIRKKDVHILETTKGSGVKFSVGELSDINDE-FLEFHLKYT 543
Query: 570 DXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFAKTAISQN--YVQPXXXXXXXXX 627
P I + A L+V VS + A + + Y +P
Sbjct: 544 RAEEEVISMLCKKAEEFIPLIPAMAQLIATLDVFVSLSTFAATSSGIYTRPNLLPLGSKR 603
Query: 628 XXXNG-RHPLYETLVDT-YIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQ 685
RHP+ E + +IPND+ + + R+ ++TGAN GKS +L
Sbjct: 604 LELKQCRHPVIEGNSEKPFIPNDVVL------------DKCRLIILTGANMGGKSTYLRS 651
Query: 686 NGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATP 745
L + LA IG FVP +A I +VD I TRV + ++ STF + S L AT
Sbjct: 652 AALSILLAQIGSFVPCSSATISVVDGIFTRVGASDKQSQGISTFMAEMLDCSAILQRATK 711
Query: 746 RSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGV 805
S ++IDE G+GT DG + AI +D C + A TH++E+ +E G
Sbjct: 712 NSFVVIDELGRGTSTFDGFGIASAIAQDILNRIQCLSIFA-THFHEMGK----LAEQPGA 766
Query: 806 VFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQE 865
V + + ++ E I LYK+ G+A SFG+ AK G+ ++++ +A +
Sbjct: 767 VALQMGVQIENNE-----------IHMLYKVFEGVAQCSFGLQVAKMVGIDENVINKAAQ 815
Query: 866 L 866
L
Sbjct: 816 L 816
>ECU03g0540 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 730
Score = 123 bits (308), Expect = 2e-27
Identities = 129/547 (23%), Positives = 217/547 (39%), Gaps = 78/547 (14%)
Query: 320 GKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNIFSIVNEMSK 379
G RLL L PL NK IE R ++ SL IL K P++ + +S
Sbjct: 255 GWRLLHRMLLQPLRNKDEIERRLDIVDSLRTLNLGIL--------KRFPDLLRLSKRVSS 306
Query: 380 GAVKLSVWRKYISFCTKTVEIINLIHILYDSSDNCRLFNTIKNDLDKSMMLKILKKTE-- 437
G V L + I +TV+ I ++ S + L + L K + + + E
Sbjct: 307 GRVSL----REILRLAQTVDTIP--ELMSSFSSSLALSKDVGETLKKIFLAFVPFRNEIT 360
Query: 438 SVLDLEGSLNQDAIVIKDKVRIELDEARGTYFELEGVLNLVANEANNTLISTLQSNEEKL 497
V+DLE + ++ ++ V L + E++G +
Sbjct: 361 RVIDLEAA-EENVYRVRPDVSERLQKLNRALAEVDGKMQKEYERVCGIYPRAKVDRNSGA 419
Query: 498 FKKLNGRNALINAIYLPQLGYLLCVDASIEDMFDPAVLYWTEIFREQNVIYYKNDDTKVM 557
FK Y D ++ F E+ + + + ++
Sbjct: 420 FKTAKAE-------------YQRSQDLFKKEGF-------VELSFVKGGVSFTTRVLSLL 459
Query: 558 DEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAILLSGKCFAELEVLVSFAKTAISQNYVQ 617
+E L I D + A+ N P + A ++V +F+ A + Y +
Sbjct: 460 NERRESLKKEIDDEEKEIMDGVKTALKNYTPYLESLNHLTALVDVFSAFSIKATLKGYSR 519
Query: 618 PXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANAS 677
P NG HP+ E YIPN ++M +R+ V+TG N
Sbjct: 520 PIVGGTMLEIE--NGFHPVLED--QDYIPNSIKM------------EDRRMCVVTGPNMG 563
Query: 678 GKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMS 737
GKS FL G+I LAH+GC+VPA+ A I ++D I TRV + STF ++ ++
Sbjct: 564 GKSTFLKTCGVIALLAHMGCYVPAEYASIPILDGIYTRVGAGDCSFTGSSTFMMEMADIA 623
Query: 738 KCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNI 797
+ L++P SL++IDE G+GT +DGLS+ A+ + S + +TH+ E+ ++
Sbjct: 624 RICRLSSPESLIIIDELGRGTSAVDGLSIAQAVKEHLILKKSL--CLCATHFPELCGDDV 681
Query: 798 LTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQ 857
L + A+ + +Y++ GI SFGI A+ G
Sbjct: 682 LNKK-----------------------AKSDGTLLMYEVVDGICDTSFGIMVAEKVGFPA 718
Query: 858 SIVQRAQ 864
+++ A+
Sbjct: 719 EVIEMAK 725
>At4g02070 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1324
Score = 122 bits (307), Expect = 2e-27
Identities = 157/617 (25%), Positives = 254/617 (40%), Gaps = 71/617 (11%)
Query: 272 KDRLFLDDDTLAALHIFKPIQIPGHFCEITKTGYS-SVFDLLNHTTSELGKRLLKSWLAS 330
K + LD L L IF+ + GYS +++ LN + GKRLLK+WLA
Sbjct: 693 KQHMVLDAAALENLEIFENSR---------NGGYSGTLYAQLNQCITASGKRLLKTWLAR 743
Query: 331 PLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNI-------FSIVNEMSKGAVK 383
PL N LI+ERQ + +++ G+N + SL +P++ FS + + K
Sbjct: 744 PLYNTELIKERQDAV-AILRGENLPYSLEFRKSLSRLPDMERLIARMFSSIEASGRNGDK 802
Query: 384 LSVWRKYISFCTKTVEIINLIHILYDSSDNCRLFNTIKNDLDKSMMLKILKKTESVLDLE 443
+ ++ + E I+ + ++ C I +L +L +S+ ++
Sbjct: 803 VVLYEDTAK--KQVQEFISTLRGCETMAEACSSLRAILKHDTSRRLLHLLTPGQSLPNIS 860
Query: 444 GSLNQDAIVIKDKVRIELDEARGTYFELEGVLNLVANEANNTLISTLQSNEEKLFKKLNG 503
S+ KD G EG A+E + T++ E L K L
Sbjct: 861 SSIKY----FKDAFDWVEAHNSGRVIPHEG-----ADEEYDCACKTVEEFESSLKKHLKE 911
Query: 504 RNAL-----INAIYLPQLGYLLCVDASIEDMFDPAVLYWTEIFREQNVI--YYKNDDTKV 556
+ L IN + + + YLL V S+ +V + E+ + + Y+ K+
Sbjct: 912 QRKLLGDASINYVTVGKDEYLLEVPESLSG----SVPHDYELCSSKKGVSRYWTPTIKKL 967
Query: 557 MDEHYGDLHGIISDXXXXXXXXXQNAV-----LNTKPAILLSGKCFAELEVLVSFAKTAI 611
+ E L S+ Q + K L+S AEL+VL+S A
Sbjct: 968 LKE----LSQAKSEKESALKSISQRLIGRFCEHQEKWRQLVSAT--AELDVLISLAFA-- 1019
Query: 612 SQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVI 671
S +Y H L + D G N+ ++ S I
Sbjct: 1020 SDSYEGVRCRPVISGSTSDGVPHLSATGLGHPVLRGDSLGRGSFVPNNVKIGGAEKASFI 1079
Query: 672 --TGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTF 729
TG N GKS L Q L V LA IG VPA+ + VDKI R+ ++ + QSTF
Sbjct: 1080 LLTGPNMGGKSTLLRQVCLAVILAQIGADVPAETFEVSPVDKICVRMGAKDHIMAGQSTF 1139
Query: 730 EIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHY 789
+ ++ + L+ AT SL+++DE G+GT DG ++ ++++ F C R STHY
Sbjct: 1140 LTELSETAVMLTSATRNSLVVLDELGRGTATSDGQAIAESVLEHFIEKVQC-RGFFSTHY 1198
Query: 790 NEVFSPNILTSEINGVVFYKTE---ILLQVMEKENKGNARDEMITFLYKLSTGIATNSFG 846
+ + V Y+T L + + +G E +TFLY+L+ G S+G
Sbjct: 1199 HRL------------SVDYQTNPKVSLCHMACQIGEGIGGVEEVTFLYRLTPGACPKSYG 1246
Query: 847 IFCAKNCGLRQSIVQRA 863
+ A+ GL ++QRA
Sbjct: 1247 VNVARLAGLPDYVLQRA 1263
>CE28985 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1186
Score = 121 bits (303), Expect = 6e-27
Identities = 68/201 (33%), Positives = 107/201 (52%), Gaps = 17/201 (8%)
Query: 668 ISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQS 727
+ ++TG N GKS + Q ++ LAHIG VPA + R+ +D+I TR+ + + +S
Sbjct: 957 VMLLTGPNMGGKSTLMRQTAVLAILAHIGSMVPAFSMRLTPIDRIFTRIGANDRIMCGES 1016
Query: 728 TFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIAST 787
TF I+ + L AT SLLL+DE G+GT DG ++ A+++ S +C R ST
Sbjct: 1017 TFFIELKETDIMLKNATKHSLLLVDELGRGTSTFDGTAIASAVLQKISDDLAC-RTFFST 1075
Query: 788 HYNEVFS-----PNILTSEINGVVFYKTEILLQVMEKENKGNARDEMITFLYKLSTGIAT 842
HY+ + PN+ + + VV +KEN + E +TFLY+L +GI
Sbjct: 1076 HYHSICDSFTNHPNVRLAHMKCVV-----------DKENNEDPTMEDVTFLYELESGICP 1124
Query: 843 NSFGIFCAKNCGLRQSIVQRA 863
S+G + AK G+ +V+ A
Sbjct: 1125 KSYGFYAAKLAGIDHQVVRNA 1145
>Hs4504191 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1360
Score = 119 bits (297), Expect = 3e-26
Identities = 77/282 (27%), Positives = 140/282 (49%), Gaps = 27/282 (9%)
Query: 633 RHPLYETLV--DTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIV 690
RHP D +IPND+ ++G + + N ++TG N GKS + Q GL+
Sbjct: 1095 RHPCITKTFFGDDFIPNDI-LIG--CEEEEQENGKAYCVLVTGPNMGGKSTLMRQAGLLA 1151
Query: 691 FLAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLL 750
+A +GC+VPA+ R+ +D++ TR+ + + +STF ++ ++ + L AT SL+L
Sbjct: 1152 VMAQMGCYVPAEVCRLTPIDRVFTRLGASDRIMSGESTFFVELSETASILMHATAHSLVL 1211
Query: 751 IDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKT 810
+DE G+GT DG ++ A++K+ + + C R + STHY+ L + + V +
Sbjct: 1212 VDELGRGTATFDGTAIANAVVKELAETIKC-RTLFSTHYHS------LVEDYSQNVAVRL 1264
Query: 811 EILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
+ ++E E + + E ITFLYK G S+G A+ L + ++Q+
Sbjct: 1265 GHMACMVENECE-DPSQETITFLYKFIKGACPKSYGFNAARLANLPEEVIQK-------- 1315
Query: 871 ADGFDIAKNYSKLTIEELNQFRIDQDIAKEFVAWDLDLESIH 912
G A+ + K+ R+ +++ +D E++H
Sbjct: 1316 --GHRKAREFEKMN----QSLRLFREVCLASERSTVDAEAVH 1351
>7298155 [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 854
Score = 114 bits (286), Expect = 5e-25
Identities = 99/349 (28%), Positives = 156/349 (44%), Gaps = 41/349 (11%)
Query: 582 AVLNTKPAILLSGKCFAELEVLVSFAKTAISQN--YVQPXXXXXXXXXXXXNG-RHPLYE 638
AV P LL+ + A+L+ LVSFA A S YV+P RHP E
Sbjct: 520 AVGYAAPLTLLNNE-LAQLDCLVSFAIAARSAPTPYVRPKMLEEGARELVLEDVRHPCLE 578
Query: 639 TLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCF 698
+ + + + D N + +ITG N GKS ++ G V +AHIG F
Sbjct: 579 ------LQEHVNFIANSVDFKKEECN---MFIITGPNMGGKSTYIRSVGTAVLMAHIGAF 629
Query: 699 VPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGT 758
VP A I +VD IL RV +++ K STF ++ + S + AT +SL++IDE G+GT
Sbjct: 630 VPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGT 689
Query: 759 DVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTEILLQVME 818
+G + +I + ++ + C + A TH++E+ E L V
Sbjct: 690 STYEGCGIAWSIAEHLAKETKCFTLFA-THFHEITK--------------LAETLSTVKN 734
Query: 819 KENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQIAD-GFDIA 877
A + T LY++ +G+ SFGI A+ + +VQ AQE+ + D D
Sbjct: 735 CHMAAVADADDFTLLYQVRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDEHVDKQ 794
Query: 878 KNYSKLTIEEL-----------NQFRID-QDIAKEFVAWDLDLESIHSD 914
K K +E++ N I+ +D+ + + D+E + SD
Sbjct: 795 KKEDKALLEKIQVAIQQLSTAGNNVDINVEDLTQLVTQFTKDIEQLDSD 843
Score = 51.6 bits (122), Expect = 6e-06
Identities = 45/213 (21%), Positives = 101/213 (47%), Gaps = 12/213 (5%)
Query: 266 VRQLMLKDRLFLDDDTLAALHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLK 325
++QL L + LD +AAL+I PG + + SV +L+H + G RL+
Sbjct: 288 IKQLDLNRFVHLDSAAVAALNIMPK---PGTHPSMPSYRWQSVLGVLDHCRTPQGHRLMG 344
Query: 326 SWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKYMPNIFSIVNE-MSKGAVKL 384
W+ PL ++ ++ +R +++ L++ + + + SL Y+ + +V + + A++
Sbjct: 345 QWVKQPLRSRNILNDRHNIVQCLLESPDTM----ETLSLDYLKRLKQMVEQVVDFEAIER 400
Query: 385 SVWRKYISFCTKTVEIINLIHILYDSSDNCRLFNTIKNDLDKSMMLKILKKTESVLDLEG 444
+ SF ++ +E+ ++ LY + + + + +LD +K+ +
Sbjct: 401 GEYLVKASFDSRLMELQQMMTELYSKMEELQFKCSQELNLDGKNQVKLESVAKLGHHFRI 460
Query: 445 SLNQDAIVIKDKVRIELDEARG----TYFELEG 473
++ D+++ K+K +D +G T +LEG
Sbjct: 461 TVKDDSVLRKNKNYRIVDVIKGGVRFTSDKLEG 493
>SPBC24C6.12c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 434
Score = 111 bits (278), Expect = 5e-24
Identities = 78/239 (32%), Positives = 116/239 (47%), Gaps = 23/239 (9%)
Query: 633 RHPLYETLVDT-YIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVF 691
RHP E D +IPND+ + G+ + + +ITG N GKS ++ Q G+I
Sbjct: 142 RHPCLEAQDDVKFIPNDVNLEHGSSE----------LLIITGPNMGGKSTYIRQVGVITV 191
Query: 692 LAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLI 751
+A IGC VP + A + ++D IL RV +S K STF + + + L ATPRSL++I
Sbjct: 192 MAQIGCPVPCEVADLDIIDAILARVGASDSQLKGISTFMAEMLETATILRAATPRSLIII 251
Query: 752 DEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTE 811
DE G+GT DG + AI + C + A THY+E+ L+ EI V
Sbjct: 252 DELGRGTSTTDGFGLAWAITEHIVTQIGCFCLFA-THYHEMTK---LSEEITTV--KNLH 305
Query: 812 ILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
+ V + E+K + LY + G + SFGI AK I++ A ++
Sbjct: 306 VTAYVGDSESKD------VALLYNVCEGASDRSFGIHVAKLAHFPPKIIEMASNKAAEL 358
>SPCC285.16c [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1254
Score = 111 bits (277), Expect = 6e-24
Identities = 70/239 (29%), Positives = 120/239 (49%), Gaps = 24/239 (10%)
Query: 633 RHP-LYETLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVF 691
RHP + + T++PND+ +LGG N + V+TG N +GKS L Q + V
Sbjct: 993 RHPCINASAASTFVPNDV-VLGGESPN---------MIVLTGPNMAGKSTLLRQVCIAVI 1042
Query: 692 LAHIGCFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLI 751
+A +GC+VPA A I + I TR+ + + +STF ++ ++ K L P+SL+++
Sbjct: 1043 MAQLGCWVPAKRASITPMTSIYTRLGANDDIMSARSTFMVELSETKKILDECGPKSLVIL 1102
Query: 752 DEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTE 811
DE G+GT DG ++ A++ + C STHY + V +
Sbjct: 1103 DELGRGTSTYDGHAIAYAVLHHLVSNIGCLGFF-STHYQSL------------CVDFMHH 1149
Query: 812 ILLQVMEKENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
+++M+ + + +TFLYKL GI S+G+ A GL + ++ A+E +++
Sbjct: 1150 RQVRLMQMAAAVDEKIRRVTFLYKLEDGICPKSYGMNVASMAGLPEKVIDAAEEKASEL 1208
>Hs20535615 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 936
Score = 111 bits (277), Expect = 6e-24
Identities = 131/581 (22%), Positives = 246/581 (41%), Gaps = 63/581 (10%)
Query: 307 SVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKY 366
++F +LN+T + G R L+S + PL + I R ++ L+ + LF L + +
Sbjct: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEE--LFFGLQSVISR 391
Query: 367 M---PNIFSIVNEMSKGAVKLSVWRKYIS--FCTKTVEIINLIHILYDSSDNCRLFNTIK 421
+ S++ ++ K + K + + T+E+++ + I + N L
Sbjct: 392 FLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC-NTPLLRAYY 450
Query: 422 NDLDKSMMLKILKKTESVLD-----LEGSLN---QDAIVIKDKVRIELDEARGTYFEL-E 472
L+ IL+K ++V++ ++G LN Q ++ + LD AR TY E+ +
Sbjct: 451 GSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVD 510
Query: 473 GVLNLVAN--EANNTLISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIEDMF 530
+ +++ E + + T S+ F ++ + I LP
Sbjct: 511 DIAGMISQLGEKYSLPLRTSFSSARGFFIQMT-----TDCIALPS--------------- 550
Query: 531 DPAVLYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAI 590
D + +I + +N + + D M+E + I + + +
Sbjct: 551 DQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCL 610
Query: 591 LLSGKCFAELEVLVSFAKTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLR 650
+ L++L+SFA +YV+P G HP+ E +
Sbjct: 611 YKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIK---QGWHPILEKI---------- 657
Query: 651 MLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVD 710
N+T+ +ITG N SGKS +L Q L +A IG +VPA+ + +
Sbjct: 658 SAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAK 717
Query: 711 KILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAI 770
+I TR+ T + + STF + +++ L A +SL+LIDE G+GT+ +G+ + A+
Sbjct: 718 QIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAV 777
Query: 771 IKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMI 830
+ + + +TH+ E+ + L + + F +V +N + E I
Sbjct: 778 CEYLLSLKAF--TLFATHFLELCHIDALYPNVENMHF-------EVQHVKNTSRNK-EAI 827
Query: 831 TFLYKLSTGIA-TNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
+ YKLS G+ ++G+ A+ L SIV A+E+TTQI
Sbjct: 828 LYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQI 868
>Hs4505251 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 936
Score = 109 bits (273), Expect = 2e-23
Identities = 130/581 (22%), Positives = 246/581 (41%), Gaps = 63/581 (10%)
Query: 307 SVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKY 366
++F +LN+T + G R L+S + PL + I R ++ L+ + LF L + +
Sbjct: 334 TLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEE--LFFGLQSVISR 391
Query: 367 M---PNIFSIVNEMSKGAVKLSVWRKYIS--FCTKTVEIINLIHILYDSSDNCRLFNTIK 421
+ S++ ++ + + K + + T+E+++ + I + N L
Sbjct: 392 FLDTEQLLSVLVQIPEQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNC-NTPLLRAYY 450
Query: 422 NDLDKSMMLKILKKTESVLD-----LEGSLN---QDAIVIKDKVRIELDEARGTYFEL-E 472
L+ IL+K ++V++ ++G LN Q ++ + LD AR TY E+ +
Sbjct: 451 GSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVD 510
Query: 473 GVLNLVAN--EANNTLISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIEDMF 530
+ +++ E + + T S+ F ++ + I LP
Sbjct: 511 DIAGMISQLGEKYSLPLRTSLSSVRGFFIQMT-----TDCIALPS--------------- 550
Query: 531 DPAVLYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTKPAI 590
D + +I + +N + + D M+E + I + + +
Sbjct: 551 DQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCL 610
Query: 591 LLSGKCFAELEVLVSFAKTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTYIPNDLR 650
+ L++L+SFA +YV+P G HP+ E +
Sbjct: 611 YKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIK---QGWHPILEKI---------- 657
Query: 651 MLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVD 710
N+T+ +ITG N SGKS +L Q L +A IG +VPA+ + +
Sbjct: 658 SAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAK 717
Query: 711 KILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAI 770
+I TR+ T + + STF + +++ L A +SL+LIDE G+GT+ +G+ + A+
Sbjct: 718 QIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAV 777
Query: 771 IKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKENKGNARDEMI 830
+ + + +TH+ E+ + L + + F +V +N + E I
Sbjct: 778 CEYLLSLKAF--TLFATHFLELCHIDALYPNVENMHF-------EVQHVKNTSRNK-EAI 827
Query: 831 TFLYKLSTGIA-TNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
+ YKLS G+ ++G+ A+ L SIV A+E+TTQI
Sbjct: 828 LYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQI 868
>At4g25540 [L] KOG0218 Mismatch repair MSH3
Length = 1076
Score = 105 bits (262), Expect = 3e-22
Identities = 160/715 (22%), Positives = 290/715 (40%), Gaps = 144/715 (20%)
Query: 236 LSCL----IKSMDHFS--AVDFDECEMFNF-FEKVNI----VRQLMLKDRLFLDDDTLAA 284
+SCL I +M H + A+ C + F FE++ R L + L +TL
Sbjct: 353 MSCLTVHTIMNMPHLTVQALALTFCHLKQFGFERILYQGASFRSLSSNTEMTLSANTLQQ 412
Query: 285 LHIFKPIQIPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKV 344
L + K + + +++G S+F +NHT + G RLL+ W+ PL ++ LI R
Sbjct: 413 LEVVK------NNSDGSESG--SLFHNMNHTLTVYGSRLLRHWVTHPLCDRNLISARLDA 464
Query: 345 IRSLIDGKNAILFDDLSNSL------------KYMPNIFSIVNEMSKGAVKLSVWRKYIS 392
+ + + LS+ L ++ + S++ MS+ + +
Sbjct: 465 VSEISACMGSHSSSQLSSELVEEGSERAIVSPEFYLVLSSVLTAMSRSSDIQRGITRIFH 524
Query: 393 FCTKTVEI------INLIHILYDSSDNCRLFNT-----------------------IKND 423
K E+ L+++ SS R+ N IK D
Sbjct: 525 RTAKATEVKIWPVLCPLMYVPVSSSPGLRVLNFLDEKFIAVMEAILLAGKQIQRLGIKQD 584
Query: 424 LDKSMMLK------ILKKTESVLD----------LEGSLNQDAIVIKDKVRIELDEARGT 467
+ M +L+K SV+ L +LN++A V D + I L +
Sbjct: 585 SEMRSMQSATVRSTLLRKLISVISSPVVVDNAGKLLSALNKEAAVRGDLLDI-LITSSDQ 643
Query: 468 YFELEGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIE 527
+ EL A +A + L S+ KKL A+ N +L G ++ ++
Sbjct: 644 FPELAE-----ARQAVLVIREKLDSSIASFRKKL----AIRNLEFLQVSGITHLIELPVD 694
Query: 528 DMFDPAVLYWTEIFREQNVIYYKN-------DDTKVMDEHYGDLHGIISDXXXXXXXXXQ 580
+ W ++ + I Y D+ + EH ++ D
Sbjct: 695 SKVP---MNWVKVNSTKKTIRYHPPEIVAGLDELALATEHLAIVNRASWDSFLKSFSRYY 751
Query: 581 NAVLNTKPAILLSGKCFAELEVLVSFAKTAISQNYVQPXXXXXXX--XXXXXNGRHPLYE 638
+ K A+ + A L+ L S + + ++NYV+P +GRHP+ E
Sbjct: 752 T---DFKAAV----QALAALDCLHSLSTLSRNKNYVRPEFVDDCEPVEINIQSGRHPVLE 804
Query: 639 TLV-DTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGC 697
T++ D ++PND + + + +ITG N GKS ++ Q LI +A +G
Sbjct: 805 TILQDNFVPNDTIL----------HAEGEYCQIITGPNMGGKSCYIRQVALISIMAQVGS 854
Query: 698 FVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKG 757
FVPA A++ ++D + TR+ +S+ +STF L ++E G+G
Sbjct: 855 FVPASFAKLHVLDGVFTRMGASDSIQHGRSTF------------------LEELNELGRG 896
Query: 758 TDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVV--FYKTEILLQ 815
T DG+++ A ++ C V+ THY E+ +++ G V ++ + + LQ
Sbjct: 897 TSTHDGVAIAYATLQHLLAEKRC-LVLFVTHYPEIAE---ISNGFPGSVGTYHVSYLTLQ 952
Query: 816 VMEKENKGNARDEMITFLYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI 870
++KG+ + +T+LYKL G+ + SFG A+ + S ++RA + ++
Sbjct: 953 ----KDKGSYDHDDVTYLYKLVRGLCSRSFGFKVAQLAQIPPSCIRRAISMAAKL 1003
>ECU10g0710 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 922
Score = 99.8 bits (247), Expect = 2e-20
Identities = 67/206 (32%), Positives = 109/206 (52%), Gaps = 21/206 (10%)
Query: 666 KRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVAKT 725
+RI V+TGAN GKS L V L+ +G V L D+I TR+ R+ +AK
Sbjct: 729 RRILVLTGANMGGKSTLLRTICFNVILSQVGMDVCCKRMETPLFDRIFTRIGARDDLAKG 788
Query: 726 QSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRVIA 785
+STF I+ + S L +T SL+++DE G+GT DG + A++ ++ + C V+
Sbjct: 789 ESTFMIELGETSNILRHSTRDSLVIMDELGRGTSTKDGGCIARAVL-EYLKKKEC-HVLF 846
Query: 786 STHYNEVFSPNILTSEINGVV-FYKTEILLQVMEKENKGNARDEMITFLYKLSTGIATNS 844
STHY+ + E+ GV Y + ++ RD I FLYKL G++ +S
Sbjct: 847 STHYHGII------GEVEGVSNGYMSSVI----------KGRD--IVFLYKLVAGVSGDS 888
Query: 845 FGIFCAKNCGLRQSIVQRAQELTTQI 870
G++ A+ G+ +IV+RA+ + ++
Sbjct: 889 HGLYVARMAGVPDAIVERAEGIRKEL 914
>CE24714 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 842
Score = 96.7 bits (239), Expect = 2e-19
Identities = 124/599 (20%), Positives = 252/599 (41%), Gaps = 81/599 (13%)
Query: 307 SVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNAILFDDLSNSLKY 366
++ +LNHT + G RLL+S + P ++ LI+ RQ+ I LI GK L D L +L
Sbjct: 238 TLMSVLNHTVTTNGYRLLRSSVLQPSTDVYLIQSRQEAIEELI-GKPQ-LKDKLRRTLSR 295
Query: 367 MPNIFSIVNEMSKGAVKLSVWRKYISFCTKTVEIINLIHILYDSSDNCRLFNTIKND--- 423
+ ++ + + +V K +II L+H L L ++ K
Sbjct: 296 AHELDRVIAMCIQTSTSWTVRESE----AKINQIIKLMHTLKVIQGIRTLLHSAKMKSNI 351
Query: 424 ------------LDKSMMLKILKKTESVLD-LEGSL---NQDAIVIKDKVRIELDEARGT 467
D+ M + + K +S+LD + SL N I+ V ++LD AR T
Sbjct: 352 LIEKTEFLKDPRFDQIMNILVEKVDDSLLDGKKNSLHLQNTKCYAIRHFVAVQLDLARQT 411
Query: 468 YFELEGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNALINAIYLPQLGYLLCVDASIE 527
Y E+ + + ++ ++ + +G +++ + + + V E
Sbjct: 412 YEEI--------------IRNVEETGAREIAEYFHGNSSVRLSFSQSRGFHYTFVTRQAE 457
Query: 528 DMFDPAVLYWTEIFREQNVIYYKNDDTKVMDEHYGDLHGIISDXXXXXXXXXQNAVLNTK 587
+ P Y+ ++FR + + + + ++ L ++++ + + +
Sbjct: 458 SVTIPR--YFLDVFRNRTTVTFNSRKVIAYNDR---LEQVVAEMFLASDVIVCDMIEEMQ 512
Query: 588 PAILL---SGKCFAELEVLVSFAKTAISQNYVQPXXXXXXXXXXXXNGRHPLYETLVDTY 644
P I + + + ++ L A + ++ +P GRHP+ +
Sbjct: 513 PMIPVLYYAMDALSSIDFLCGLATYSDLRDTCKPTFGPSFSIS---QGRHPILDW----- 564
Query: 645 IPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNA 704
+D T NDT +R +ITG N +GKS +L Q + +A IGCF+PA+ A
Sbjct: 565 --DDSEK---TITNDTCLTRDRRFGIITGPNMAGKSTYLKQTAQLAIMAQIGCFIPANYA 619
Query: 705 RIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGL 764
+ + ++I +R+ + + + +S F + + + + A SL+++DE + T +G+
Sbjct: 620 SLPIFNRIFSRMGHNDELIRNKSAFASEMSDAAAIVQYADKNSLVVLDELARSTSTEEGI 679
Query: 765 SMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFY-KTEILLQVMEKENKG 823
++ AI + + S +TH+ ++ + ++ I+ F +T+ K +G
Sbjct: 680 AITYAICEKVLKLQS--YTFLATHFLDIAALANYSNAIDNYHFLPQTDENSTKKHKLLRG 737
Query: 824 NARDEMITF-LYKLSTGIATNSFGIFCAKNCGLRQSIVQRAQELTTQI-ADGFDIAKNY 880
R + F L +LST + +++ AQ L T++ A+ D ++Y
Sbjct: 738 QYRGPLYGFELVELST----------------IPDEVIEHAQSLATELRANVEDTERDY 780
>YFL003c [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 878
Score = 95.1 bits (235), Expect = 4e-19
Identities = 119/583 (20%), Positives = 247/583 (41%), Gaps = 63/583 (10%)
Query: 233 TMSLSCLIKSMDHFSAVDFDECEMFNFFEKVNIVRQLMLKDRLFLDDDTLAALHIFKPIQ 292
T +L ++ + + N F K+ I + ++ + +D T+ L + +
Sbjct: 224 TFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFE-GTENTMLIDSKTVRGLELVEN-- 280
Query: 293 IPGHFCEITKTGYSSVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGK 352
++ K G S ++ L+ T++++G+R L++ + PL+++ IE R + + L
Sbjct: 281 ------KLDKNGIS-LWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEEL--KA 331
Query: 353 NAILFDDLSNSLKYMPNI---FSIVNEMSKGAVKLSVWRKYISFCTKTVEII-NLIHILY 408
N L L +K +P++ FS + ++ A+K Y+ +T++ + +L L
Sbjct: 332 NDDLLQKLRLEMKSLPDLDKLFSRLLCINHSAIKPDQRINYVLLLKETLQSVKSLKDALN 391
Query: 409 DSSDNCRLFNTIKNDLDKSMMLKILKKTESVLDLEGSLNQDAIVIKDKVRIELDEARGTY 468
D RL + K + +++I K S + N+D + +++ +
Sbjct: 392 DQLIQSRLISETKKIFNNDAIMEIEKLINSCI------NEDCVWASSAIQLLNQRSYAVK 445
Query: 469 FELEGVLNLVANEANNTLISTLQSNEEKLFKKLNGRNAL-INAIYLPQLGYLLCVD---- 523
+ G+L++ + + ++ + + L +N + ++ Y G+ L +
Sbjct: 446 SDSNGLLDV-----SRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEF 500
Query: 524 ----ASIEDMFDPAVLYWTEIFREQNVIYYKNDDTK-VMDEHYGDLHGIISDXXXXXXXX 578
A++ D+F + I I KN K VM+E ++S+
Sbjct: 501 TDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEIL-----LLSEETVDELL- 554
Query: 579 XQNAVLNTKPAILLSGKCFAELEVLVSFAKTAISQNYVQPXXXXXXXXXXXXNGRHPLYE 638
+ + + + + A L+++ SF NY P + RHPL E
Sbjct: 555 --DKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIR---DSRHPLLE 609
Query: 639 TLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIGCF 698
++ ++PN + + + +ITG N SGKSV+L Q LI +A +G
Sbjct: 610 KVLKNFVPNTISS----------TKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSG 659
Query: 699 VPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGT 758
+PA + ++ R V +S+ T S F + +M+ L +LL++DE G+G+
Sbjct: 660 IPALYGSFPVFKRLHAR-VCNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGS 718
Query: 759 DVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSE 801
+ DG + A+ + R+ + V STH+ ++ P I++ +
Sbjct: 719 SIADGFCVSLAVTEHLLRTEA--TVFLSTHFQDI--PKIMSKK 757
>At4g17380 [L] KOG0220 Mismatch repair ATPase MSH4 (MutS family)
Length = 574
Score = 93.2 bits (230), Expect = 2e-18
Identities = 75/279 (26%), Positives = 132/279 (46%), Gaps = 28/279 (10%)
Query: 581 NAVLNTKPAILLSGKCFAELEVLV-SFAKTAISQ---NYVQPXXXXXXXXXXXXNGRHPL 636
+A+ A+ L + L+++V SFA T ++ Y +P GRHP+
Sbjct: 305 DAIREDISALTLLAEVLCLLDMIVNSFAHTISTKPVDRYSRPELTDSGPLAIDA-GRHPI 363
Query: 637 YETLVDTYIPNDLRMLGGTFDNDTWNNNFKRISVITGANASGKSVFLTQNGLIVFLAHIG 696
E++ + ++ N + M T + V+ G N SGKS +L Q L+V LA IG
Sbjct: 364 LESIHNDFVSNSIFMSEAT-----------NMLVVMGPNMSGKSTYLQQVCLVVILAQIG 412
Query: 697 CFVPADNARIGLVDKILTRVVTRESVAKTQSTFEIDANQMSKCLSLATPRSLLLIDEFGK 756
C+VPA A I +VD+I TR+ T +++ STF + + + + T RSL+++DE G+
Sbjct: 413 CYVPARFATIRVVDRIFTRMGTMDNLESNSSTFMTEMRETAFIMQNVTNRSLIVMDELGR 472
Query: 757 GTDVIDGLSMFGAIIKDFSRSSSCPRVIASTHYNEVFSPNILTSEINGVVFYKTEIL-LQ 815
T DGL+M + SC + S VF+ ++ + ++ ++L
Sbjct: 473 ATSSSDGLAM----------AWSCCEYLLSLKAYTVFATHMDSLAELATIYPNVKVLHFY 522
Query: 816 VMEKENKGNARDEMITFLYKLST-GIATNSFGIFCAKNC 853
V ++N+ + + + Y+ T G A + + + NC
Sbjct: 523 VDIRDNRLDFKVLSVFLSYEFETLGTAAECYIVLISFNC 561
>At3g24320 [L] KOG0217 Mismatch repair ATPase MSH6 (MutS family)
Length = 1022
Score = 82.0 bits (201), Expect = 4e-15
Identities = 59/204 (28%), Positives = 103/204 (49%), Gaps = 18/204 (8%)
Query: 664 NFKRISVITGANASGKSVFLTQNGLIVFLAHIGCFVPADNARIGLVDKILTRVVTRESVA 723
+ + + ++TG N GKS L L G VPA++A I D I+ + + +S
Sbjct: 663 DMQSLFLLTGPNGGGKSSLLRSICAAALLGISGLMVPAESACIPHFDSIMLHMKSYDSPV 722
Query: 724 KTQSTFEIDANQMSKCLSLATPRSLLLIDEFGKGTDVIDGLSMFGAIIKDFSRSSSCPRV 783
+S+F+++ +++ +S AT RSL+LIDE +GT+ G + G++++ +S C +
Sbjct: 723 DGKSSFQVEMSEIRSIVSQATSRSLVLIDEICRGTETAKGTCIAGSVVESLD-TSGCLGI 781
Query: 784 IASTHYNEVFSPNILTSEINGVVFYKTEILLQVMEKEN-KGNARDEMITFLYKLSTGIAT 842
+ STH + +FS + I YK M EN +G + +KL+ G+
Sbjct: 782 V-STHLHGIFSLPLTAKNIT----YK------AMGAENVEGQTKP-----TWKLTDGVCR 825
Query: 843 NSFGIFCAKNCGLRQSIVQRAQEL 866
S AK G+ +S++QRA+ L
Sbjct: 826 ESLAFETAKREGVPESVIQRAEAL 849
>SPBC19G7.01c [L] KOG0219 Mismatch repair ATPase MSH2 (MutS family)
Length = 582
Score = 54.7 bits (130), Expect = 7e-07
Identities = 41/175 (23%), Positives = 89/175 (50%), Gaps = 14/175 (8%)
Query: 307 SVFDLLNHTTSELGKRLLKSWLASPLSNKILIEERQKVIRSLIDGKNA--ILFDDLSNSL 364
S++ LLNH + +G R L+ W+ PL + IE R ++ +L++ A +L DD + L
Sbjct: 339 SLYGLLNHCRTAMGARNLRRWIVQPLLDAKSIERRHDLVSALVEDAEARQLLLDD-DHLL 397
Query: 365 KYMPNIFSIVNEMSKGAVKLSVWRKYISFCTKTVEIINLIHILYDSSDNC--RLFNTIKN 422
+ +P+I + +++G+ L + +I+ ++ L + +++ + N
Sbjct: 398 RSIPDIPKLCRRLTRGSASLEDVVRIYQMAKALPKIVTVLDSLTSEHKDLVDKVYTNVLN 457
Query: 423 DLDKSMMLKILKKTESVLDLEGSLNQDAIVIKDK-------VRIELDEARGTYFE 470
+ K++ K+++ E+ +DLE +L+ +I+ + +R LDE + + FE
Sbjct: 458 NHCKNLE-KLIELVETTIDLE-ALDSHQYIIRAEFDEELLDLRQRLDELQHSIFE 510
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,606,714
Number of Sequences: 60738
Number of extensions: 2015530
Number of successful extensions: 5203
Number of sequences better than 1.0e-05: 28
Number of HSP's better than 0.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 5099
Number of HSP's gapped (non-prelim): 52
length of query: 934
length of database: 30,389,216
effective HSP length: 116
effective length of query: 818
effective length of database: 23,343,608
effective search space: 19095071344
effective search space used: 19095071344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)