ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4080 good D KOG0653 Cell cycle control, cell division, chromosome partitioning Cyclin B and related kinase-activating proteins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4080 1441309 1439978 -444
(444 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDL155w [D] KOG0653 Cyclin B and related kinase-activating proteins 389 e-108
YLR210w [D] KOG0653 Cyclin B and related kinase-activating proteins 388 e-108
SPBC582.03 [D] KOG0653 Cyclin B and related kinase-activating pr... 275 1e-73
SPAPB2B4.03 [D] KOG0653 Cyclin B and related kinase-activating p... 231 1e-60
YPR119w [D] KOG0653 Cyclin B and related kinase-activating proteins 213 6e-55
YGR108w [D] KOG0653 Cyclin B and related kinase-activating proteins 212 8e-55
Hs4757930 [D] KOG0653 Cyclin B and related kinase-activating pro... 190 4e-48
Hs14327896 [D] KOG0653 Cyclin B and related kinase-activating pr... 189 5e-48
SPCC4E9.02 [D] KOG0653 Cyclin B and related kinase-activating pr... 183 4e-46
YPR120c [D] KOG0653 Cyclin B and related kinase-activating proteins 181 1e-45
SPBC16E9.17c [D] KOG0653 Cyclin B and related kinase-activating ... 178 2e-44
At1g20610 [D] KOG0653 Cyclin B and related kinase-activating pro... 176 8e-44
YGR109c [D] KOG0653 Cyclin B and related kinase-activating proteins 175 1e-43
At4g35620 [D] KOG0653 Cyclin B and related kinase-activating pro... 171 2e-42
At2g17620 [D] KOG0653 Cyclin B and related kinase-activating pro... 171 3e-42
ECU08g0260 [D] KOG0653 Cyclin B and related kinase-activating pr... 170 4e-42
At1g76310 [D] KOG0653 Cyclin B and related kinase-activating pro... 160 4e-39
At5g06150 [D] KOG0653 Cyclin B and related kinase-activating pro... 155 1e-37
At3g11520 [D] KOG0653 Cyclin B and related kinase-activating pro... 153 4e-37
At2g26760 [D] KOG0653 Cyclin B and related kinase-activating pro... 153 4e-37
Hs4502611 [D] KOG0654 G2/Mitotic-specific cyclin A 152 7e-37
7291478 [D] KOG0653 Cyclin B and related kinase-activating proteins 150 4e-36
At1g44110 [D] KOG0654 G2/Mitotic-specific cyclin A 150 5e-36
At5g43080 [D] KOG0654 G2/Mitotic-specific cyclin A 147 3e-35
7294661 [D] KOG0654 G2/Mitotic-specific cyclin A 147 3e-35
At1g47220 [D] KOG0654 G2/Mitotic-specific cyclin A 142 8e-34
At1g47210 [D] KOG0654 G2/Mitotic-specific cyclin A 142 1e-33
At4g37490 [D] KOG0653 Cyclin B and related kinase-activating pro... 142 1e-33
At1g77390 [D] KOG0654 G2/Mitotic-specific cyclin A 139 8e-33
Hs14719420_2 [D] KOG0653 Cyclin B and related kinase-activating ... 138 2e-32
At1g80370 [D] KOG0654 G2/Mitotic-specific cyclin A 137 2e-32
At1g47230 [D] KOG0654 G2/Mitotic-specific cyclin A 136 5e-32
Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A 135 9e-32
At1g16330 [D] KOG0653 Cyclin B and related kinase-activating pro... 134 2e-31
CE27776 [D] KOG0653 Cyclin B and related kinase-activating proteins 131 2e-30
CE13315 [D] KOG0653 Cyclin B and related kinase-activating proteins 131 2e-30
At5g25380 [D] KOG0654 G2/Mitotic-specific cyclin A 131 2e-30
At1g15570 [D] KOG0654 G2/Mitotic-specific cyclin A 130 5e-30
At5g11300 [D] KOG0654 G2/Mitotic-specific cyclin A 127 3e-29
CE06570 [D] KOG0653 Cyclin B and related kinase-activating proteins 117 3e-26
CE28122 [D] KOG0653 Cyclin B and related kinase-activating proteins 115 2e-25
CE23835 [D] KOG0653 Cyclin B and related kinase-activating proteins 115 2e-25
At1g20590 [D] KOG0653 Cyclin B and related kinase-activating pro... 110 4e-24
Hs16306525_2 [D] KOG0653 Cyclin B and related kinase-activating ... 103 7e-22
CE03820 [D] KOG0654 G2/Mitotic-specific cyclin A 102 1e-21
SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating ... 94 5e-19
Hs4502621 [D] KOG0654 G2/Mitotic-specific cyclin A 85 2e-16
Hs17318565 [D] KOG0655 G1/S-specific cyclin E 84 5e-16
Hs17318567 [D] KOG0655 G1/S-specific cyclin E 82 2e-15
Hs22048740 [D] KOG0655 G1/S-specific cyclin E 81 4e-15
At1g34460_1 [D] KOG0653 Cyclin B and related kinase-activating p... 80 8e-15
Hs17318561 [D] KOG0655 G1/S-specific cyclin E 77 4e-14
Hs17318559 [D] KOG0655 G1/S-specific cyclin E 77 4e-14
7298245 [D] KOG0655 G1/S-specific cyclin E 77 7e-14
Hs16950655 [D] KOG0656 G1/S-specific cyclin D 75 1e-13
7293153 [D] KOG0656 G1/S-specific cyclin D 75 3e-13
HsM4502615 [D] KOG0656 G1/S-specific cyclin D 74 4e-13
CE24832 [D] KOG0655 G1/S-specific cyclin E 73 1e-12
ECU09g1030 [D] KOG0653 Cyclin B and related kinase-activating pr... 69 1e-11
CE21610 [D] KOG0656 G1/S-specific cyclin D 68 3e-11
Hs22062947 [D] KOG0653 Cyclin B and related kinase-activating pr... 66 9e-11
Hs4502617 [D] KOG0656 G1/S-specific cyclin D 60 5e-09
At1g14750_2 [D] KOG0653 Cyclin B and related kinase-activating p... 57 6e-08
YAL040c [D] KOG0653 Cyclin B and related kinase-activating proteins 56 9e-08
Hs5802992 [D] KOG0653 Cyclin B and related kinase-activating pro... 56 1e-07
At5g10440 [D] KOG0656 G1/S-specific cyclin D 55 2e-07
At3g50070 [D] KOG0656 G1/S-specific cyclin D 55 2e-07
Hs4502619 [D] KOG0656 G1/S-specific cyclin D 55 3e-07
Hs20541478 [D] KOG0653 Cyclin B and related kinase-activating pr... 55 3e-07
At5g67260 [D] KOG0656 G1/S-specific cyclin D 53 1e-06
At2g22490 [D] KOG0656 G1/S-specific cyclin D 51 4e-06
At1g70210 [D] KOG0656 G1/S-specific cyclin D 50 5e-06
YPL256c [D] KOG0653 Cyclin B and related kinase-activating proteins 50 9e-06
>YDL155w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 427
Score = 389 bits (999), Expect = e-108
Identities = 182/320 (56%), Positives = 249/320 (76%)
Query: 124 EEAETGGDISEEMEDVDESFTPLVPVVTEHSERLYQYVYERLHREEPDPNDEDTWDPVMV 183
E+ E D E ED +E PL+ ++++ + +R DPND+D +D VMV
Sbjct: 106 EQEEPVEDDGESEEDEEEDQEPLLLQHYASDTLVWEHAFRTYYRTTLDPNDDDVYDVVMV 165
Query: 184 SEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLT 243
+E + EIFE+++ LE + PNP Y++ QPEL W +RSTLIDWIVQVH++FQLLPETL+L
Sbjct: 166 AELSNEIFEYMRKLEDLYKPNPYYMDKQPELRWSFRSTLIDWIVQVHEKFQLLPETLYLC 225
Query: 244 VNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAE 303
+NIIDR+L K+ V +N+ QLVGAA+LFIA+KYEEINCPT+KD +YM +N Y+R ++L AE
Sbjct: 226 INIIDRYLCKEVVPVNKFQLVGAASLFIAAKYEEINCPTIKDFVYMSENCYSRNDLLDAE 285
Query: 304 RFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAA 363
R ++N L FE GWPGPMSFLRR+SKADDYE+DTRT+AKYLLE++IM+ +++A PSWLAA
Sbjct: 286 RTILNGLEFELGWPGPMSFLRRISKADDYEHDTRTLAKYLLESTIMDHRLVSAQPSWLAA 345
Query: 364 GAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATERHKAIFDKYSRSRH 423
GAY+LSKII+G WS H+YYS YT+EQ++PLAT+IL++CR+A++RH AI+ KYS R+
Sbjct: 346 GAYFLSKIILGQNQWSLAHVYYSNYTQEQILPLATIILENCRYASKRHNAIWRKYSSRRY 405
Query: 424 RKSAFVVAKWISMAESRLEQ 443
S+ +VAKWI++AE R+E+
Sbjct: 406 LHSSQIVAKWIALAEHRVER 425
>YLR210w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 460
Score = 388 bits (997), Expect = e-108
Identities = 204/447 (45%), Positives = 286/447 (63%), Gaps = 47/447 (10%)
Query: 5 QQRVALGDVTSQINNRA------------NRFSVDGDSKKAFVDAGFLKEKRVKNAKEND 52
Q+RVALGDVTSQ N+ N F ++ A V +++R +++D
Sbjct: 49 QRRVALGDVTSQKANKIHNAIHNKFHQTKNNFEIENIRSSALVK----EQQRDVRHEDSD 104
Query: 53 LFSGHDDDLVVARAQKLREQTLVSSVSTESIRSQQLSSNSNETVQHHLIXXXXXXXXXXX 112
F L + + SS E + + + V I
Sbjct: 105 YF--------------LIDSSEGSSTDDEQVNEDAIDDLLSRRVNDQQIQADEVY----- 145
Query: 113 XXXXXXXFKEDEEAETGGDISEEMEDVDESFTPLVPVVTEHSERLYQYVYERLHREEPDP 172
ED + E D+ EE DVD PL P+ + + +E+ R P+P
Sbjct: 146 ---------EDFDGEMQ-DVIEE--DVDSQIEPLSPINNDEIQTELDRAFEKYFRSVPNP 193
Query: 173 NDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDR 232
D+DT D VMV EY +IF +L+ LE K+ PNP Y+++Q ELTW +R T+IDW+VQ+H R
Sbjct: 194 LDDDTHDVVMVVEYASDIFYYLRELEVKYRPNPYYMQNQVELTWPFRRTMIDWLVQLHFR 253
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
FQLLPETL+LT+NI+DRFLSKK VTLNR QLVG +ALFIA+K+EEINCPTL D++YML+N
Sbjct: 254 FQLLPETLYLTINIVDRFLSKKTVTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLEN 313
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPE 352
YTR++I+RAE++MI+TL FE GWPGPM FLRR+SKADDY+++ RT+AKYLLET+I+EP+
Sbjct: 314 TYTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPK 373
Query: 353 IIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATERHK 412
++AA PSWLAAGAY+LS+ I+G WS +H++YSGYT Q+IPLA++IL++C++A+ RH
Sbjct: 374 LVAAAPSWLAAGAYFLSRTILGSNDWSLKHVFYSGYTSSQIIPLASLILENCKNASRRHH 433
Query: 413 AIFDKYSRSRHRKSAFVVAKWISMAES 439
+I+ KY +H + + +V +WI E+
Sbjct: 434 SIWKKYFDQKHYRCSQIVEEWIVSTEA 460
>SPBC582.03 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 482
Score = 275 bits (702), Expect = 1e-73
Identities = 166/432 (38%), Positives = 247/432 (56%), Gaps = 40/432 (9%)
Query: 5 QQRVALGDVTSQINNRANRFSVDGDSKKAFVDAGFLKEKRVKNAKENDLFSGHDDDLVVA 64
++R AL DV+ N N+ V SK V + +E + DD+
Sbjct: 57 KKRHALDDVS----NFHNKEGVPLASKNTNVRHTTASVSTRRALEEKSIIPATDDE---- 108
Query: 65 RAQKLREQTLVSSVSTESIRSQQLSSNSNETVQHHLIXXXXXXXXXXXXXXXXXXFKEDE 124
A K R Q V + S S+ Q LS+ S+ H + F +D+
Sbjct: 109 PASKKRRQPSVFNSSVPSL-PQHLSTKSHSVSTHGV-----------------DAFHKDQ 150
Query: 125 EAETGGDISEEME-DVDESFTPLVPVVTEHSERLYQYVYERLHREEPDPNDEDTW-DPVM 182
I ++++ DVDE VV++ +L++ E ++ D D + W DP+M
Sbjct: 151 AT-----IPKKLKKDVDER------VVSKDIPKLHRDSVESPESQDWDDLDAEDWADPLM 199
Query: 183 VSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFL 242
VSEY ++IFE+L LE + P+P Y++ Q EL WK R L DW+++VH RF+LLPETLFL
Sbjct: 200 VSEYVVDIFEYLNELEIETMPSPTYMDRQKELAWKMRGILTDWLIEVHSRFRLLPETLFL 259
Query: 243 TVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRA 302
VNIIDRFLS + +LN+LQLVG AALFIASKYEE+ CP++++ +YM D Y EEIL+A
Sbjct: 260 AVNIIDRFLSLRVCSLNKLQLVGIAALFIASKYEEVMCPSVQNFVYMADGGYDEEEILQA 319
Query: 303 ERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLA 362
ER+++ L F +P PM+FLRR+SKAD Y+ TRTVAKYL+E +++ +++ PPS
Sbjct: 320 ERYILRVLEFNLAYPNPMNFLRRISKADFYDIQTRTVAKYLVEIGLLDHKLLPYPPSQQC 379
Query: 363 AGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATERHKAIFDKYSRSR 422
A A YL++ ++G W+ ++YSGY E QLI + +++ + + H+A F KY+ +
Sbjct: 380 AAAMYLAREMLGRGPWNRNLVHYSGYEEYQLISVVKKMINYLQKPVQ-HEAFFKKYASKK 438
Query: 423 HRKSAFVVAKWI 434
K++ V WI
Sbjct: 439 FMKASLFVRDWI 450
>SPAPB2B4.03 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 411
Score = 231 bits (590), Expect = 1e-60
Identities = 113/259 (43%), Positives = 174/259 (66%), Gaps = 2/259 (0%)
Query: 173 NDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDR 232
+D + +P+M EY EIFE+++ L+ K PNP+Y++ Q ELTWK R L +W+V++H
Sbjct: 123 DDHLSSNPLMAEEYAPEIFEYIRKLDLKCLPNPKYMDQQKELTWKMREILNEWLVEIHSN 182
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
F L+PETL+L VNIIDRFLS++ +L++ QL G AL IASKYEE+ CP++++ +YM D
Sbjct: 183 FCLMPETLYLAVNIIDRFLSRRSCSLSKFQLTGITALLIASKYEEVMCPSIQNFVYMTDG 242
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPE 352
A+T E++ AER+M+N LNF+ +P P++FLR++S+A+ Y+ TRT+ KYL E + + +
Sbjct: 243 AFTVEDVCVAERYMLNVLNFDLSYPSPLNFLRKISQAEGYDAQTRTLGKYLTEIYLFDHD 302
Query: 353 IIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYS-GYTEEQLIPLATMILDSCRHATERH 411
++ P S +AA A YLS+ ++ W+ + + S GY E +L +A ++L E H
Sbjct: 303 LLRYPMSKIAAAAMYLSRRLLRRGPWTPKLVESSGGYEEHELKEIAYIMLHYHNKPLE-H 361
Query: 412 KAIFDKYSRSRHRKSAFVV 430
KA F KYS R K++ V
Sbjct: 362 KAFFQKYSSKRFLKASIFV 380
>YPR119w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 491
Score = 213 bits (541), Expect = 6e-55
Identities = 115/267 (43%), Positives = 166/267 (62%), Gaps = 3/267 (1%)
Query: 168 EEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIV 227
E D + ED DP MVSEY +IFE+L LE P + +Q + R L++W+V
Sbjct: 211 EWEDLDAEDVNDPFMVSEYVNDIFEYLHQLEVITLPKKEDL-YQHRNIHQNRDILVNWLV 269
Query: 228 QVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDML 287
++H++F LLPETL+L +NI+DRFL K+ V L++LQLVG + LFIASKYEE+ P++K
Sbjct: 270 KIHNKFGLLPETLYLAINIMDRFLGKELVQLDKLQLVGTSCLFIASKYEEVYSPSIKHFA 329
Query: 288 YMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETS 347
D A T +EI E+F++ TL F +P PM+FLRR+SKADDY+ +RT+AK+LLE S
Sbjct: 330 SETDGACTEDEIKEGEKFILKTLKFNLNYPNPMNFLRRISKADDYDIQSRTLAKFLLEIS 389
Query: 348 IMEPEIIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYS-GYTEEQLIPLATMILDSCRH 406
+++ I PS AA A ++S+ ++G W I+YS GYT+E+L P+ MI+D
Sbjct: 390 LVDFRFIGILPSLCAAAAMFMSRKMLGKGKWDGNLIHYSGGYTKEELAPVCHMIMDYLVS 449
Query: 407 ATERHKAIFDKYSRSRHRKSAFVVAKW 433
H KY R K++ + +W
Sbjct: 450 PIV-HDEFHRKYQSRRFMKASIISVQW 475
>YGR108w [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 471
Score = 212 bits (540), Expect = 8e-55
Identities = 122/311 (39%), Positives = 189/311 (60%), Gaps = 11/311 (3%)
Query: 124 EEAETGGDISEEMEDVDESFTPLVPVVTEHSERLYQYVYERLHREEPDPNDEDTWDPVMV 183
E+++ IS +E D+ L + TE E L +Y ++ D ++ED DP+MV
Sbjct: 155 EDSKKKRPISTLVEQDDQKKFKLHELTTEE-EVLEEYEWD-------DLDEEDCDDPLMV 206
Query: 184 SEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLT 243
SE +IF++L LE PN + + + R L++WI+++H++F LLPETL+L
Sbjct: 207 SEEVNDIFDYLHHLEIITLPNKANLYKHKNIK-QNRDILVNWIIKIHNKFGLLPETLYLA 265
Query: 244 VNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAE 303
+NI+DRFL ++ V LNRLQLVG + LFIASKYEEI P++K Y D A + E+I E
Sbjct: 266 INIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGE 325
Query: 304 RFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAA 363
RF++ L+F+ + PM+FLRR+SKADDY+ +RT+AK+L+E SI++ + I PS A+
Sbjct: 326 RFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCAS 385
Query: 364 GAYYLSKIIIGLTGWSDEHIYYS-GYTEEQLIPLATMILDSCRHATERHKAIFDKYSRSR 422
A +LS+ ++G W I+YS GYT+ +L P+ +++D +T H KY R
Sbjct: 386 AAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGST-IHDEFLKKYQSRR 444
Query: 423 HRKSAFVVAKW 433
K++ + +W
Sbjct: 445 FLKASIISIEW 455
>Hs4757930 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 398
Score = 190 bits (482), Expect = 4e-48
Identities = 104/289 (35%), Positives = 177/289 (60%), Gaps = 4/289 (1%)
Query: 144 TPLVPVVTEHSERLYQYVYERLHREEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSP 203
+P V+ E L Q + L + D ++ED +P + S+Y +I+++L+ LE S
Sbjct: 92 SPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSI 151
Query: 204 NPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQL 263
NP +++ + ++ + R+ L+DW+VQVH +F+LL ETL++ V I+DRFL + V+ +LQL
Sbjct: 152 NPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQL 210
Query: 264 VGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFL 323
VG AL +ASKYEE+ P ++D +Y+ DNAYT +I E ++ L FE G P P+ FL
Sbjct: 211 VGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFL 270
Query: 324 RRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGAYYLSKIIIGLTGWSDEHI 383
RR SKA + + + T+AKYL+E ++++ +++ PS +AA A LS+ ++G W+ +
Sbjct: 271 RRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQ 330
Query: 384 YYSGYTEEQLIPLATMILDSCRHATE---RHKAIFDKYSRSRHRKSAFV 429
YY+GYTE +++ + + + E + AI +KY+ S+ K + +
Sbjct: 331 YYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI 379
>Hs14327896 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 433
Score = 189 bits (481), Expect = 5e-48
Identities = 100/258 (38%), Positives = 159/258 (60%), Gaps = 4/258 (1%)
Query: 171 DPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVH 230
D + ED DP + SEY +I+ +L+ LE + + P+Y+ + E+T R+ LIDW+VQV
Sbjct: 155 DVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQ 213
Query: 231 DRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYML 290
+F+LL ET+++TV+IIDRF+ V LQLVG A+FIASKYEE+ P + D ++
Sbjct: 214 MKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVT 273
Query: 291 DNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIME 350
DN YT+ +I + E ++ LNF G P P+ FLRR SK + + + T+AKYL+E ++++
Sbjct: 274 DNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLD 333
Query: 351 PEIIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDS---CRHA 407
+++ PPS +AAGA+ L+ I+ W+ +Y YTEE L+P+ + +
Sbjct: 334 YDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQG 393
Query: 408 TERHKAIFDKYSRSRHRK 425
+H + +KY+ S+H K
Sbjct: 394 LTKHMTVKNKYATSKHAK 411
>SPCC4E9.02 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 310
Score = 183 bits (465), Expect = 4e-46
Identities = 93/189 (49%), Positives = 128/189 (67%), Gaps = 2/189 (1%)
Query: 145 PLVPVVTEHSERLYQYVYERLHREEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPN 204
P +P T+ RL + P P D +T DP MV +Y EIF +++ LERK +P
Sbjct: 124 PTIPEWTKEDLAALSEAAARL-QANPSPEDIET-DPSMVPDYDPEIFHYMQSLERKLAPP 181
Query: 205 PRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLV 264
P Y+ Q E+ W R L+DWIVQV F+LLPETLFL VN+IDRFLS K V+L ++QLV
Sbjct: 182 PNYMSVQQEIDWVTRHMLVDWIVQVQIHFRLLPETLFLAVNLIDRFLSIKVVSLQKVQLV 241
Query: 265 GAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLR 324
G +AL IA KYEEI+ P++ + +++ +T +EI+RAER+M+ L+F+ WPGPMSFLR
Sbjct: 242 GLSALLIACKYEEIHPPSIYNFAHVVQGIFTVDEIIRAERYMLMLLDFDISWPGPMSFLR 301
Query: 325 RVSKADDYE 333
R+S+AD Y+
Sbjct: 302 RISRADSYD 310
>YPR120c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 435
Score = 181 bits (460), Expect = 1e-45
Identities = 109/324 (33%), Positives = 178/324 (54%), Gaps = 17/324 (5%)
Query: 120 FKEDEEAETGGDISEEMEDVDESFTPLVPVVTEHSERLYQYVYERLHREEPDPNDEDTWD 179
+ + AE + EE ED D + +V + + V E + ++ D ++D D
Sbjct: 103 YNDRTAAEQEEEEEEEGEDDDAA-----SIVNKKRRIDAEGVSEIVGWQDLDYVEKD--D 155
Query: 180 PVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPE---LTWKYRSTLIDWIVQVHDRFQLL 236
MV+EY+ EIF L E + P+ Y+ + L R+ L+DW+V+VH++FQ
Sbjct: 156 TAMVAEYSAEIFAFLYRRELETLPSHNYLLDKTSKYYLRPSMRTILVDWLVEVHEKFQCY 215
Query: 237 PETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTR 296
PETLFL++N++DRFL+K +VT+N+LQL+ +LFIA+K+EE+N P L + Y+ D A ++
Sbjct: 216 PETLFLSINLMDRFLAKNKVTMNKLQLLAVTSLFIAAKFEEVNLPKLAEYAYITDGAASK 275
Query: 297 EEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAA 356
+I AE FM+ +L F GWP P++FLRR+SKADDY+ R + K++LE + + I
Sbjct: 276 NDIKNAEMFMLTSLEFNIGWPNPLNFLRRISKADDYDPVNRNIGKFILEYAYCCHQFIHL 335
Query: 357 PPSWLAAGAYYLSKIIIGLTG---WSDEHIYYSG----YTEEQLIPLATMILDSCRHATE 409
PPS ++A A Y+++ + W+ +YSG +E L ++ +
Sbjct: 336 PPSTVSAMAMYIARRMTNRNKNELWNGTLQHYSGGIDPIHDEAFQSLCIDLVKDIASSKT 395
Query: 410 RHKAIFDKYSRSRHRKSAFVVAKW 433
++ KY + R+ F KW
Sbjct: 396 HLDSLILKYKKPRYGSVYFQTFKW 419
>SPBC16E9.17c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 402
Score = 178 bits (451), Expect = 2e-44
Identities = 92/251 (36%), Positives = 147/251 (57%)
Query: 185 EYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTV 244
EY EI H++ LE +F P+ R++ QP + R+++I+WIV VH LLPE+LFL++
Sbjct: 141 EYAKEILSHMEKLEIRFMPDYRHMSAQPYYVTEMRASVINWIVGVHTCINLLPESLFLSI 200
Query: 245 NIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAER 304
N++DRFLS + V ++++L GA ALFIA KYEEI+ PT+KD+ +L+ + E+I E+
Sbjct: 201 NVLDRFLSLQNVPASKMKLCGATALFIACKYEEIHPPTVKDLEIVLEGEWIGEDICGMEK 260
Query: 305 FMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAG 364
+M+ L ++ GWPGP+SFLR ++ + +E R + KY LE S++E + S L A
Sbjct: 261 YMLMVLQYQLGWPGPVSFLRLLTIVNKWESQLRIMIKYFLEVSLVEQRFSSLRASQLVAT 320
Query: 365 AYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATERHKAIFDKYSRSRHR 424
Y + I+ WS+ +GY L+ ++L + + H AI+ KY+
Sbjct: 321 CAYTGQSILQEENWSNTLPQITGYDYMSLVSYVHLLLKCLENPFDHHYAIYSKYATPYFH 380
Query: 425 KSAFVVAKWIS 435
+ V WI+
Sbjct: 381 GISRQVHDWIA 391
>At1g20610 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 176 bits (445), Expect = 8e-44
Identities = 103/306 (33%), Positives = 168/306 (54%), Gaps = 12/306 (3%)
Query: 123 DEEAETGGDISEEMEDVDESFTPLVPVVTEHSERLYQYV-YERLHREEPDPNDEDTWD-- 179
DE + GGD +E M F + E E++ + + E +EE D D D
Sbjct: 116 DESDKEGGDSNEPM------FVQHTEAMLEEIEQMEKEIEMEDADKEEEPVIDIDACDKN 169
Query: 180 -PVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPE 238
P+ EY ++ K E+ P Y+++Q +L + R LIDW+++VH +F+L+ E
Sbjct: 170 NPLAAVEYIHDMHTFYKNFEKLSCVPPNYMDNQQDLNERMRGILIDWLIEVHYKFELMEE 229
Query: 239 TLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREE 298
TL+LT+N+IDRFL+ Q+ +LQLVG AL +A KYEE++ P + D++ + D AY+R E
Sbjct: 230 TLYLTINVIDRFLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLILISDKAYSRRE 289
Query: 299 ILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPP 358
+L E+ M NTL F F P P F++R KA + ++ +++E ++E E++ P
Sbjct: 290 VLDMEKLMANTLQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELCLVEYEMLEYLP 349
Query: 359 SWLAAGAYYLSKIII-GLTGWSDEHIYYSGYTEEQLIPLA-TMILDSCRHATERHKAIFD 416
S LAA A Y ++ + G WS +++GY E+QL+ A M+ + T + +
Sbjct: 350 SKLAASAIYTAQCTLKGFEEWSKTCEFHTGYNEKQLLACARKMVAFHHKAGTGKLTGVHR 409
Query: 417 KYSRSR 422
KY+ S+
Sbjct: 410 KYNTSK 415
>YGR109c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 380
Score = 175 bits (443), Expect = 1e-43
Identities = 99/263 (37%), Positives = 153/263 (57%), Gaps = 8/263 (3%)
Query: 179 DPVMVSEYTIEIFEHLKFLERKFSPNPRYI---EHQPELTWKYRSTLIDWIVQVHDRFQL 235
DP MV+EYT IF HL E + P Y+ + L R+ LIDW+V+VH++F
Sbjct: 113 DPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHC 172
Query: 236 LPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYT 295
LPETLFL +N++DRFLS+ V LN+LQL+ LFIA K+EE+ P + + Y+ D A T
Sbjct: 173 LPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLPKITNFAYVTDGAAT 232
Query: 296 REEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIA 355
E I +AE F++++L + P P++F+RR+SKAD+Y +TR +AK+++E SI + I
Sbjct: 233 VEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIH 292
Query: 356 APPSWLAAGAYYLS-KIIIGLTGWSDEHIYYSGYTEEQLIP----LATMILDSCRHATER 410
PS+LAA + Y++ KI + W + I+YSG + + P + +++
Sbjct: 293 LKPSYLAAMSMYIARKIKNENSKWDETFIHYSGGIDIESDPAFKDFISELVEDIAVPDTN 352
Query: 411 HKAIFDKYSRSRHRKSAFVVAKW 433
++ KY + +H F V W
Sbjct: 353 LDSLRLKYKKPKHGMVYFKVFDW 375
>At4g35620 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 171 bits (433), Expect = 2e-42
Identities = 94/260 (36%), Positives = 156/260 (59%), Gaps = 4/260 (1%)
Query: 167 REEP--DPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLID 224
+EEP D ++ D + + EY ++++ + ER Y+ Q +++ K R+ LID
Sbjct: 151 QEEPVLDIDEYDANNSLAAVEYVQDLYDFYRKTERFSCVPLDYMAQQFDISDKMRAILID 210
Query: 225 WIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLK 284
W+++VHD+F+L+ ETLFLTVN+IDRFLSK+ V +LQLVG AL +A KYEE++ P ++
Sbjct: 211 WLIEVHDKFELMNETLFLTVNLIDRFLSKQAVARKKLQLVGLVALLLACKYEEVSVPIVE 270
Query: 285 DMLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLL 344
D++ + D AYTR ++L E+ M++TL F P FL+R KA + +A +L+
Sbjct: 271 DLVVISDKAYTRTDVLEMEKIMLSTLQFNMSLPTQYPFLKRFLKAAQSDKKLEILASFLI 330
Query: 345 ETSIMEPEIIAAPPSWLAAGAYYLSKIII-GLTGWSDEHIYYSGYTEEQLIPLA-TMILD 402
E ++++ E++ PPS LAA A Y ++ I G + W+ ++ Y+E QL+ M+
Sbjct: 331 ELALVDYEMVRYPPSLLAATAVYTAQCTIHGFSEWNSTCEFHCHYSENQLLECCRRMVRL 390
Query: 403 SCRHATERHKAIFDKYSRSR 422
+ T++ + KYS S+
Sbjct: 391 HQKAGTDKLTGVHRKYSSSK 410
>At2g17620 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 429
Score = 171 bits (432), Expect = 3e-42
Identities = 99/276 (35%), Positives = 160/276 (57%), Gaps = 4/276 (1%)
Query: 168 EEP--DPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDW 225
EEP D + D+ + + EY +++ + +ER Y+ Q +L K R+ LIDW
Sbjct: 151 EEPIVDIDVLDSKNSLAAVEYVQDLYAFYRTMERFSCVPVDYMMQQIDLNEKMRAILIDW 210
Query: 226 IVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKD 285
+++VHD+F L+ ETLFLTVN+IDRFLSK+ V +LQLVG AL +A KYEE++ P ++D
Sbjct: 211 LIEVHDKFDLINETLFLTVNLIDRFLSKQNVMRKKLQLVGLVALLLACKYEEVSVPVVED 270
Query: 286 MLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLE 345
++ + D AYTR ++L E+ M++TL F P FL+R KA + +A +L+E
Sbjct: 271 LVLISDKAYTRNDVLEMEKTMLSTLQFNISLPTQYPFLKRFLKAAQADKKCEVLASFLIE 330
Query: 346 TSIMEPEIIAAPPSWLAAGAYYLSKIII-GLTGWSDEHIYYSGYTEEQLIPLATMILD-S 403
+++E E++ PPS LAA + Y ++ + G W+ ++ Y+E+QL+ + ++
Sbjct: 331 LALVEYEMLRFPPSLLAATSVYTAQCTLDGSRKWNSTCEFHCHYSEDQLMECSRKLVSLH 390
Query: 404 CRHATERHKAIFDKYSRSRHRKSAFVVAKWISMAES 439
R AT ++ KYS S+ A A ++ES
Sbjct: 391 QRAATGNLTGVYRKYSTSKFGYIAKCEAAHFLVSES 426
>ECU08g0260 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 300
Score = 170 bits (430), Expect = 4e-42
Identities = 85/213 (39%), Positives = 137/213 (63%), Gaps = 6/213 (2%)
Query: 181 VMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETL 240
VMV +Y+ ++FE+ +++ F YI ++WK RS L+DWI+ +HD+ L +TL
Sbjct: 49 VMVDKYSDDVFEYFSTIDKPFV----YINDG--VSWKMRSLLVDWIIDIHDKLGLCHDTL 102
Query: 241 FLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEIL 300
FL +N IDRFLS + + ++LQLVG +AL IA KYEE+ CP L+ ++ + + T E++
Sbjct: 103 FLAINFIDRFLSMRSIPSSKLQLVGISALMIACKYEEVVCPALQTLVLLTEKTLTGEDVR 162
Query: 301 RAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSW 360
+AE++M++TLN++ + P++FLR+ SKA++YE +RTV KYLLE + E + S
Sbjct: 163 KAEKYMLHTLNYDLQYVSPLNFLRKCSKANNYEICSRTVGKYLLELMTLYEEFLRFKGSV 222
Query: 361 LAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQL 393
AA A YL++ I + I YSG+T++ +
Sbjct: 223 RAAAAMYLARKITSQDQCKNLFIMYSGHTKDDI 255
>At1g76310 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 457
Score = 160 bits (405), Expect = 4e-39
Identities = 89/242 (36%), Positives = 143/242 (58%), Gaps = 5/242 (2%)
Query: 184 SEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLT 243
S + IE F + L+ + P Y+E+Q ++ + R L DW+++VH +F+L+ ETL+LT
Sbjct: 203 SSFKIETFSII--LQCRSCVPPNYMENQHDINERMRGILFDWLIEVHYKFELMEETLYLT 260
Query: 244 VNIIDRFLSKKQ-VTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRA 302
+N+IDRFL+ Q + +LQLVG A+ +A KYEE++ P + D++ + D AYTR EIL
Sbjct: 261 INLIDRFLAVHQHIARKKLQLVGVTAMLLACKYEEVSVPVVDDLILISDKAYTRTEILDM 320
Query: 303 ERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLA 362
E+ M NTL F F P P F+RR KA + ++ +++E ++E E++ PS LA
Sbjct: 321 EKLMANTLQFNFCLPTPYVFMRRFLKAAQSDKKLELLSFFMIELCLVEYEMLQYTPSQLA 380
Query: 363 AGAYYLSKIII-GLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHA-TERHKAIFDKYSR 420
A A Y ++ + G WS ++SGYTEE L+ + ++ A T + + KY+
Sbjct: 381 ASAIYTAQSTLKGYEDWSKTSEFHSGYTEEALLECSRKMVGLHHKAGTGKLTGVHRKYNT 440
Query: 421 SR 422
S+
Sbjct: 441 SK 442
>At5g06150 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 445
Score = 155 bits (391), Expect = 1e-37
Identities = 92/261 (35%), Positives = 149/261 (56%), Gaps = 3/261 (1%)
Query: 171 DPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVH 230
D ++ D + + EY +++ K +E++ P Y+ Q E+ K R+ LIDW+++VH
Sbjct: 167 DIDESDKDNHLAAVEYVDDMYSFYKEVEKESQPK-MYMHIQTEMNEKMRAILIDWLLEVH 225
Query: 231 DRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYML 290
+F+L ETL+LTVNIIDRFLS K V LQLVG +AL IASKYEEI P + D++Y+
Sbjct: 226 IKFELNLETLYLTVNIIDRFLSVKAVPKRELQLVGISALLIASKYEEIWPPQVNDLVYVT 285
Query: 291 DNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIME 350
DNAY+ +IL E+ ++ L + P FL R KA + + + +L E +M
Sbjct: 286 DNAYSSRQILVMEKAILGNLEWYLTVPTQYVFLVRFIKASMSDPEMENMVHFLAELGMMH 345
Query: 351 PEIIAAPPSWLAAGAYYLSKIIIGLT-GWSDEHIYYSGYTEEQLIPLATMI-LDSCRHAT 408
+ + PS LAA A Y ++ + + W+D +++GYTE +++ + ++ R
Sbjct: 346 YDTLTFCPSMLAASAVYTARCSLNKSPAWTDTLQFHTGYTESEIMDCSKLLAFLHSRCGE 405
Query: 409 ERHKAIFDKYSRSRHRKSAFV 429
R +A++ KYS++ + A V
Sbjct: 406 SRLRAVYKKYSKAENGGVAMV 426
>At3g11520 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 427
Score = 153 bits (387), Expect = 4e-37
Identities = 91/238 (38%), Positives = 135/238 (56%), Gaps = 3/238 (1%)
Query: 185 EYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTV 244
EY +++ K + + P Y+ QPE+ K RS LIDW+V+VH +F L PETL+LTV
Sbjct: 171 EYVEDMYIFYKEVVNESKPQ-MYMHTQPEIDEKMRSILIDWLVEVHVKFDLSPETLYLTV 229
Query: 245 NIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAER 304
NIIDRFLS K V LQLVG +AL IASKYEEI P + D++Y+ DN+Y +IL E+
Sbjct: 230 NIIDRFLSLKTVPRRELQLVGVSALLIASKYEEIWPPQVNDLVYVTDNSYNSRQILVMEK 289
Query: 305 FMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAG 364
++ L + P FL R KA + + +L E +M + + PS LAA
Sbjct: 290 TILGNLEWYLTVPTQYVFLVRFIKASGSDQKLENLVHFLAELGLMHHDSLMFCPSMLAAS 349
Query: 365 AYYLSKIIIGLT-GWSDEHIYYSGYTEEQLIPLATMILDSCRHATE-RHKAIFDKYSR 420
A Y ++ + T W+D +++GY+E QL+ + ++ A E + + + KYS+
Sbjct: 350 AVYTARCCLNKTPTWTDTLKFHTGYSESQLMDCSKLLAFIHSKAGESKLRGVLKKYSK 407
>At2g26760 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 387
Score = 153 bits (387), Expect = 4e-37
Identities = 92/249 (36%), Positives = 147/249 (58%), Gaps = 5/249 (2%)
Query: 185 EYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTV 244
EY +IF+ + +E + YI QPE+ K RS LIDW+V VH +F+L+PETL+LT+
Sbjct: 129 EYVEDIFKFYRTVEEEGGIKD-YIGSQPEINEKMRSILIDWLVDVHRKFELMPETLYLTI 187
Query: 245 NIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAER 304
N++DRFLS V LQL+G A+ IA KYEEI P + D + + DNAY R+++L E+
Sbjct: 188 NLVDRFLSLTMVHRRELQLLGLGAMLIACKYEEIWAPEVNDFVCISDNAYNRKQVLAMEK 247
Query: 305 FMINTLNFEFGWPGPMSFLRR-VSKADDYEYDTRTVAKYLLETSIME-PEIIAAPPSWLA 362
++ + + P P FL R V A + + + YL E +M+ P ++ PS LA
Sbjct: 248 SILGQVEWYITVPTPYVFLARYVKAAVPCDAEMEKLVFYLAELGLMQYPIVVLNRPSMLA 307
Query: 363 AGAYYLSKIIIGLTG-WSDEHIYYSGYTEEQLIPLATMILDSCRHATE-RHKAIFDKYSR 420
A A Y ++ I+ T W++ +++GY+E++++ A M++ A+E + A+F KYS
Sbjct: 308 ASAVYAARQILKKTPFWTETLKHHTGYSEDEIMEHAKMLMKLRDSASESKLIAVFKKYSV 367
Query: 421 SRHRKSAFV 429
S + + A +
Sbjct: 368 SENAEVALL 376
>Hs4502611 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 465
Score = 152 bits (385), Expect = 7e-37
Identities = 81/247 (32%), Positives = 142/247 (56%), Gaps = 2/247 (0%)
Query: 179 DPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPE 238
D + V+EY EI+++L+ E + P Y++ QP++T R+ L+DW+V+V + ++L E
Sbjct: 204 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 263
Query: 239 TLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREE 298
TL+L VN +DRFLS V +LQLVG AA+ +ASKYEEI P + + +Y+ D+ YT+ +
Sbjct: 264 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 323
Query: 299 ILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPE-IIAAP 357
+L+ E ++ L F+ P FL + + T +AKY+ E S++E + +
Sbjct: 324 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYL 383
Query: 358 PSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATER-HKAIFD 416
PS +AA A+ L+ + W + ++GY+ +++P + + + R +AI +
Sbjct: 384 PSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIRE 443
Query: 417 KYSRSRH 423
KY S++
Sbjct: 444 KYKASKY 450
>7291478 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 530
Score = 150 bits (379), Expect = 4e-36
Identities = 97/272 (35%), Positives = 154/272 (55%), Gaps = 14/272 (5%)
Query: 168 EEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIV 227
E+ D ND++ V+VSEY +I+++L +E + + ++ Q E++ K R+ LIDWI
Sbjct: 241 EDIDANDKENL--VLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWIN 298
Query: 228 QVHDRFQLLPETLFLTVNIIDRFLSK-KQVTLNRLQLVGAAALFIASKYEEINCPTLKDM 286
+VH +F L ET L V IIDR+L K LQLVG ALFIA+KYEE+ P + D
Sbjct: 299 EVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDF 358
Query: 287 LYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLET 346
+++ D+ YT +I + E + ++ P P+ FLRR SKA E + T++KY +E
Sbjct: 359 VFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIEL 418
Query: 347 SIMEPEIIAAPPSWLAAGAYYLSKIII-----GLTGWSDEH-----IYYSGYTEEQLIPL 396
+ ++ E+ PS +AA + +LS ++ TG++D H +YS Y+ L P+
Sbjct: 419 ASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPI 478
Query: 397 ATMILDSCRHATE-RHKAIFDKYSRSRHRKSA 427
+I R A + + KAI++KY S+ +K A
Sbjct: 479 TRLIAKLARDAPQAKLKAIYNKYQGSKFQKIA 510
>At1g44110 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 460
Score = 150 bits (378), Expect = 5e-36
Identities = 89/272 (32%), Positives = 153/272 (55%), Gaps = 18/272 (6%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDR 232
D + DP + + + +I++HL+ E K P+ Y+E Q ++ R L+DW+++V +
Sbjct: 182 DSNNGDPQLCATFACDIYKHLRASEAKKRPDVDYMERVQKDVNSSMRGILVDWLIEVSEE 241
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
++L+PETL+LTVN IDR+LS ++ +LQL+G A + IA+KYEEI P +++ Y+ DN
Sbjct: 242 YRLVPETLYLTVNYIDRYLSGNVISRQKLQLLGVACMMIAAKYEEICAPQVEEFCYITDN 301
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDT-----RTVAKYLLETS 347
Y ++E+L E ++N L FE P FLRR +A ++ +A Y+ E S
Sbjct: 302 TYLKDEVLDMESDVLNYLKFEMTAPTTKCFLRRFVRAAHGVHEAPLMQLECMANYIAELS 361
Query: 348 IMEPEIIAAPPSWLAAGAYYLSKIIIGLT--GWSDEHIYYSGYTEEQLIPLATMILDSCR 405
++E +++ PS +AA A +L+K I+ T W+ YT+ + + L + D R
Sbjct: 362 LLEYTMLSHSPSLVAASAIFLAKYILDPTRRPWNST---LQHYTQYKAMELRGCVKDLQR 418
Query: 406 HATERH----KAIFDKYSRSRHRKSAFVVAKW 433
+ H A+ +KYS+ +++ FV K+
Sbjct: 419 LCSTAHGSTLPAVREKYSQHKYK---FVAKKF 447
>At5g43080 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 355
Score = 147 bits (371), Expect = 3e-35
Identities = 83/201 (41%), Positives = 122/201 (60%), Gaps = 6/201 (2%)
Query: 179 DPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLP 237
DP M Y IFE+L+ LE K P YIE Q ++T R L+DW+V+V + ++LL
Sbjct: 80 DPQMCGPYVTSIFEYLRQLEVKSRPLVDYIEKIQKDVTSNMRGVLVDWLVEVAEEYKLLS 139
Query: 238 ETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTRE 297
+TL+L V+ IDRFLS K V RLQL+G ++ IASKYEEI P + D Y+ DN YT++
Sbjct: 140 DTLYLAVSYIDRFLSLKTVNKQRLQLLGVTSMLIASKYEEITPPNVDDFCYITDNTYTKQ 199
Query: 298 EILRAERFMINTLNFEFGWPGPMSFLRRVSKA--DDYE---YDTRTVAKYLLETSIMEPE 352
EI++ E ++ L FE G P +FLRR ++ +D+E + YL E S+++ +
Sbjct: 200 EIVKMEADILLALQFELGNPTSNTFLRRFTRVAQEDFEMSHLQMEFLCSYLSELSMLDYQ 259
Query: 353 IIAAPPSWLAAGAYYLSKIII 373
+ PS +AA A +L++ II
Sbjct: 260 SVKFLPSTVAASAVFLARFII 280
>7294661 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 490
Score = 147 bits (371), Expect = 3e-35
Identities = 88/282 (31%), Positives = 162/282 (57%), Gaps = 12/282 (4%)
Query: 167 REEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWI 226
+E P ND + + V +Y ++I E+ + E+K P P Y+ Q +++ RS LIDW+
Sbjct: 185 KELPPRNDRQRF--LEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWL 242
Query: 227 VQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDM 286
V+V + ++L ETL+L+V +DRFLS+ V ++LQLVG AA++IA+KYEEI P + +
Sbjct: 243 VEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEF 302
Query: 287 LYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLET 346
+++ D++YT+ ++LR E+ ++ L+F+ P F+ + D + + Y+ E
Sbjct: 303 VFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISEL 362
Query: 347 SIMEPE-IIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCR 405
S+ME E + PS +++ + L++ I+G+ W+ T +L L T++L C
Sbjct: 363 SLMEGETYLQYLPSLMSSASVALARHILGMEMWTPR---LEEITTYKLEDLKTVVLHLCH 419
Query: 406 -HATERH---KAIFDKYSRSRHRKSAFVVAKWISMAESRLEQ 443
H T + +A+ +KY+R ++K A + + + M++ +Q
Sbjct: 420 THKTAKELNTQAMREKYNRDTYKKVAMMES--VEMSKDDFDQ 459
>At1g47220 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 327
Score = 142 bits (359), Expect = 8e-34
Identities = 94/262 (35%), Positives = 143/262 (53%), Gaps = 11/262 (4%)
Query: 179 DPVMVSEYTIEIFEHLKFLE--RKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQL 235
DP M Y +I+E+L+ LE K P YIE Q ++T R L+DW+V+V + F+L
Sbjct: 49 DPQMCGLYVSDIYEYLRELEVKPKLRPLHDYIEKIQEDITPSKRGVLVDWLVEVAEEFEL 108
Query: 236 LPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYT 295
+ ETL+LTV+ IDRFLS K V + LQLVG +A+FIASKYEE P ++D Y+ N YT
Sbjct: 109 VSETLYLTVSYIDRFLSLKMVNEHWLQLVGVSAMFIASKYEEKRRPKVEDFCYITANTYT 168
Query: 296 REEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEY-----DTRTVAKYLLETSIME 350
++++L+ E ++ L FE G P +FLRR + ++ + YL E S+++
Sbjct: 169 KQDVLKMEEDILLALEFELGRPTTNTFLRRFIRVAQEDFKVPNLQLEPLCCYLSELSMLD 228
Query: 351 PEIIAAPPSWLAAGAYYLSKIII--GLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHAT 408
+ PS LAA A +L++ II WS + Y L ++LD +
Sbjct: 229 YSCVKFVPSLLAASAVFLARFIILPNQHPWSQMLEECTKYKAADLQVCVEIMLDLYLSRS 288
Query: 409 E-RHKAIFDKYSRSRHRKSAFV 429
E KA+ +KY + + + A +
Sbjct: 289 EGASKAVREKYKQHKFQYVAAI 310
>At1g47210 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 372
Score = 142 bits (358), Expect = 1e-33
Identities = 83/208 (39%), Positives = 128/208 (60%), Gaps = 8/208 (3%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLE--RKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVH 230
D + DP M Y +I+E+L+ LE K P P YIE Q ++T R L+DW+V+V
Sbjct: 90 DSRSDDPQMCGPYVADIYEYLRQLEVKPKQRPLPDYIEKVQKDVTPSMRGVLVDWLVEVA 149
Query: 231 DRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYML 290
+ ++L ETL+LTV+ IDRFLS K V +LQLVG +A+ IASKYEEI+ P + D Y+
Sbjct: 150 EEYKLGSETLYLTVSHIDRFLSLKTVNKQKLQLVGVSAMLIASKYEEISPPKVDDFCYIT 209
Query: 291 DNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKA--DDYE---YDTRTVAKYLLE 345
DN ++++++++ E ++ L FE G P +F+RR ++ DD++ + YL E
Sbjct: 210 DNTFSKQDVVKMEADILLALQFELGRPTINTFMRRFTRVAQDDFKVPHLQLEPLCCYLSE 269
Query: 346 TSIMEPEIIAAPPSWLAAGAYYLSKIII 373
SI++ + + PS LAA A +L++ II
Sbjct: 270 LSILDYKTVKFVPSLLAASAVFLARFII 297
>At4g37490 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 428
Score = 142 bits (357), Expect = 1e-33
Identities = 91/281 (32%), Positives = 154/281 (54%), Gaps = 6/281 (2%)
Query: 123 DEEAETGGDISEEMEDVDESFTPLVPVVTEHSERLYQYVYERLHREE-PDPNDEDTWDPV 181
D + E G + E + + T V+T S+ E+ +E+ D + D + +
Sbjct: 103 DSDEELGLVAAREKKATKKKATTYTSVLTARSKAACGL--EKKQKEKIVDIDSADVENDL 160
Query: 182 MVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLF 241
EY +I+ K +E ++ P Y+ QP++ K R L++W++ VH RF+L PET +
Sbjct: 161 AAVEYVEDIYSFYKSVESEWRPRD-YMASQPDINEKMRLILVEWLIDVHVRFELNPETFY 219
Query: 242 LTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILR 301
LTVNI+DRFLS K V LQLVG +AL +++KYEEI P ++D++ + D+AY+ ++IL
Sbjct: 220 LTVNILDRFLSVKPVPRKELQLVGLSALLMSAKYEEIWPPQVEDLVDIADHAYSHKQILV 279
Query: 302 AERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPE-IIAAPPSW 360
E+ +++TL + P FL R KA + + YL E +M + +I PS
Sbjct: 280 MEKTILSTLEWYLTVPTHYVFLARFIKASIADEKMENMVHYLAELGVMHYDTMIMFSPSM 339
Query: 361 LAAGAYYLSKIII-GLTGWSDEHIYYSGYTEEQLIPLATMI 400
+AA A Y ++ + + W+ +++GY+E QL+ A ++
Sbjct: 340 VAASAIYAARSSLRQVPIWTSTLKHHTGYSETQLMDCAKLL 380
>At1g77390 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 454
Score = 139 bits (350), Expect = 8e-33
Identities = 90/315 (28%), Positives = 154/315 (48%), Gaps = 25/315 (7%)
Query: 139 VDESFTPLVPVVTEH---SERLYQYVYERLHREEPDPNDE-------DTWDPVMVSEYTI 188
+D S T P ++ H + + Y+ E + D +D+ D DP + + +
Sbjct: 121 LDASPTQSDPSISTHDSLTNHVVDYMVESTTDDGNDDDDDEIVNIDSDLMDPQLCASFAC 180
Query: 189 EIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNII 247
+I+EHL+ E P Y+E Q + RS LIDW+V+V + ++L PETL+L VN +
Sbjct: 181 DIYEHLRVSEVNKRPALDYMERTQSSINASMRSILIDWLVEVAEEYRLSPETLYLAVNYV 240
Query: 248 DRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMI 307
DR+L+ + LQL+G + IA+KYEE+ P ++D Y+ DN Y R E+L E ++
Sbjct: 241 DRYLTGNAINKQNLQLLGVTCMMIAAKYEEVCVPQVEDFCYITDNTYLRNELLEMESSVL 300
Query: 308 NTLNFEFGWPGPMSFLRRVSKADDYEYD-----TRTVAKYLLETSIMEPEIIAAPPSWLA 362
N L FE P FLRR +A + + +A YL E S+++ ++ PS +A
Sbjct: 301 NYLKFELTTPTAKCFLRRFLRAAQGRKEVPSLLSECLACYLTELSLLDYAMLRYAPSLVA 360
Query: 363 AGAYYLSKIII--GLTGWSDEHIYYSGYTEEQLIPLATMILDSCRH-------ATERHKA 413
A A +L++ + W+ +Y+ Y + + +L C A ++ +
Sbjct: 361 ASAVFLAQYTLHPSRKPWNATLEHYTSYRAKHMEACVKNLLQLCNEKLSSDVVAIRKNTS 420
Query: 414 IFDKYSRSRHRKSAF 428
+ + RH + +F
Sbjct: 421 LQQRSFVPRHYRKSF 435
>Hs14719420_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 1284
Score = 138 bits (347), Expect = 2e-32
Identities = 89/271 (32%), Positives = 143/271 (51%), Gaps = 6/271 (2%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRF 233
DED+ DP Y EIF ++K E +F Y+ Q E+T R+ L+DW+V+V F
Sbjct: 1006 DEDSSDPSFNPMYAKEIFSYMKEREEQFILTD-YMNRQIEITSDMRAILVDWLVEVQVSF 1064
Query: 234 QLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNA 293
++ ETL+L V ++D +L K ++LQL+GA A IA+K+EE N P + D +Y+ D+
Sbjct: 1065 EMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDN 1124
Query: 294 YTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEI 353
Y R E+L E ++N L + P FLRR ++ T T+++Y+ E ++ E
Sbjct: 1125 YQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHY 1184
Query: 354 IAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHAT-ERHK 412
+ S LAA + L+ + L W +YSGY+ +L PL + ++ + K
Sbjct: 1185 VQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDSLK 1244
Query: 413 AIFDKYSRSRHRKSAFVVAKWISMAESRLEQ 443
A++ KYS F VAK ++ +LE+
Sbjct: 1245 AVYYKYS----HPVFFEVAKIPALDMLKLEE 1271
>At1g80370 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 461
Score = 137 bits (346), Expect = 2e-32
Identities = 77/228 (33%), Positives = 129/228 (55%), Gaps = 8/228 (3%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDR 232
D D DP++ S Y +I+ +L+ E K P P ++E Q ++T R L+DW+V+V +
Sbjct: 185 DSDDKDPLLCSLYAPDIYYNLRVAELKRRPFPDFMEKTQRDVTETMRGILVDWLVEVSEE 244
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
+ L+P+TL+LTV +ID FL V RLQL+G + IASKYEEI+ P +++ ++ DN
Sbjct: 245 YTLVPDTLYLTVYLIDWFLHGNYVERQRLQLLGITCMLIASKYEEIHAPRIEEFCFITDN 304
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRT-----VAKYLLETS 347
YTR+++L E ++ +F+ P +FLRR +A + ++ +A YL E +
Sbjct: 305 TYTRDQVLEMESQVLKHFSFQIYTPTSKTFLRRFLRAAQVSFPNQSLEMEFLANYLTELT 364
Query: 348 IMEPEIIAAPPSWLAAGAYYLSKIIIGLTG--WSDEHIYYSGYTEEQL 393
+M+ + PS +AA A +L+K + + W+ +Y+ Y L
Sbjct: 365 LMDYPFLKFLPSIIAASAVFLAKWTLNQSSHPWNPTLEHYTTYKASDL 412
>At1g47230 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 369
Score = 136 bits (343), Expect = 5e-32
Identities = 76/203 (37%), Positives = 122/203 (59%), Gaps = 8/203 (3%)
Query: 179 DPVMVSEYTIEIFEHLKFLERK--FSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQL 235
DP M + +I +L+ +E K P P YIE Q +LT R+ L+DW+V+V + ++L
Sbjct: 88 DPQMCEPFASDICAYLREMEGKPKHRPLPDYIEKVQSDLTPHMRAVLVDWLVEVAEEYKL 147
Query: 236 LPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYT 295
+ +TL+LT++ +DRFLS K + +LQLVG +A+ IASKYEEI P ++D Y+ DN +T
Sbjct: 148 VSDTLYLTISYVDRFLSVKPINRQKLQLVGVSAMLIASKYEEIGPPKVEDFCYITDNTFT 207
Query: 296 REEILRAERFMINTLNFEFGWPGPMSFLRRVSKA-----DDYEYDTRTVAKYLLETSIME 350
++E++ E ++ L FE G P +FLRR ++ D + + YL E S+++
Sbjct: 208 KQEVVSMEADILLALQFELGSPTIKTFLRRFTRVAQEDFKDSQLQIEFLCCYLSELSMLD 267
Query: 351 PEIIAAPPSWLAAGAYYLSKIII 373
+ PS L+A A +L++ II
Sbjct: 268 YTCVKYLPSLLSASAVFLARFII 290
>Hs4502613 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 432
Score = 135 bits (341), Expect = 9e-32
Identities = 85/253 (33%), Positives = 140/253 (54%), Gaps = 12/253 (4%)
Query: 180 PVMVSE---YTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLL 236
PV V+E Y +I +L+ +E K P Y++ QP++T R+ L+DW+V+V + ++L
Sbjct: 169 PVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQ 228
Query: 237 PETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTR 296
ETL L VN IDRFLS V +LQLVG AA+ +ASK+EEI P + + +Y+ D+ YT+
Sbjct: 229 NETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTK 288
Query: 297 EEILRAERFMINTLNFEFGWPGPMSFLRR-VSKADDYEYDTRTVAKYLLETSIMEPE-II 354
+++LR E ++ L F+ P FL + ++A +L E S+++ + +
Sbjct: 289 KQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYL 348
Query: 355 AAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIP----LATMILDSCRHATER 410
PS +A A++L+ + W + I +GYT E L P L L + +HA
Sbjct: 349 KYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHA--- 405
Query: 411 HKAIFDKYSRSRH 423
++I +KY S++
Sbjct: 406 QQSIREKYKNSKY 418
>At1g16330 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 518
Score = 134 bits (338), Expect = 2e-31
Identities = 82/254 (32%), Positives = 139/254 (54%), Gaps = 4/254 (1%)
Query: 169 EPD--PNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWI 226
EP+ P+ +D + + V+EY +I++ E Y+ E++ R LI+W+
Sbjct: 246 EPEKLPSIDDESNQLEVAEYVDDIYQFYWTAEALNPALGHYLSAHAEVSPVTRGILINWL 305
Query: 227 VQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDM 286
++VH +F L+ ETL+LT++++DR+LS+ + N +QL+G AL +ASKYE+ P +KD+
Sbjct: 306 IEVHFKFDLMHETLYLTMDLLDRYLSQVPIHKNEMQLIGLTALLLASKYEDYWHPRIKDL 365
Query: 287 LYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLET 346
+ + +YTRE+IL ER M+ L F P P F+ R KA +A YL+E
Sbjct: 366 ISISAESYTREQILGMERSMLKQLKFRLNAPTPYVFMLRFLKAAQSNKKLEQLAFYLIEL 425
Query: 347 SIMEPEIIAAPPSWLAAGAYYLSKIIIGLTG-WSDEHIYYSGYTEEQLIPLATMILDSCR 405
++E E + PS L A A Y+++ + +T W+ ++ Y Q+ + MIL +
Sbjct: 426 CLVEYEALKYKPSLLCASAIYVARCTLHMTPVWTSLLNNHTHYNVSQMKDCSDMILRFHK 485
Query: 406 HA-TERHKAIFDKY 418
A T + ++KY
Sbjct: 486 AAKTGNLRVTYEKY 499
>CE27776 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 383
Score = 131 bits (330), Expect = 2e-30
Identities = 74/226 (32%), Positives = 129/226 (56%), Gaps = 5/226 (2%)
Query: 175 EDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQ 234
E+ +P +S+Y IF++ + E F +Y+ PE+ K R+ LIDW+V++ + F+
Sbjct: 99 EEAGNPDSISDYAQGIFDYYRHREVHFRVR-KYLHKHPEVDVKTRAILIDWMVEIQETFE 157
Query: 235 LLPETLFLTVNIIDRFLSK-KQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNA 293
L ETL+ V + D +L K K V N +Q + A+FIA+KY+E + P + D++Y+ +
Sbjct: 158 LNHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDR 217
Query: 294 YTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEI 353
++R+E+L ER + T+ ++ G P +LRR + + T T+ +++LETS+M E
Sbjct: 218 FSRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEY 277
Query: 354 IAAPPSWLAAGAYYLSKIIIGLTG---WSDEHIYYSGYTEEQLIPL 396
S LAA A+ L+ ++ W+ YSG+T E+++PL
Sbjct: 278 AMVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPL 323
>CE13315 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 384
Score = 131 bits (330), Expect = 2e-30
Identities = 74/226 (32%), Positives = 129/226 (56%), Gaps = 5/226 (2%)
Query: 175 EDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQ 234
E+ +P +S+Y IF++ + E F +Y+ PE+ K R+ LIDW+V++ + F+
Sbjct: 100 EEAGNPDSISDYAQGIFDYYRHREVHFRVR-KYLHKHPEVDVKTRAILIDWMVEIQETFE 158
Query: 235 LLPETLFLTVNIIDRFLSK-KQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNA 293
L ETL+ V + D +L K K V N +Q + A+FIA+KY+E + P + D++Y+ +
Sbjct: 159 LNHETLYNAVKLTDMYLCKTKNVDKNTIQKLACVAIFIAAKYDERSPPLVDDLIYLSGDR 218
Query: 294 YTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEI 353
++R+E+L ER + T+ ++ G P +LRR + + T T+ +++LETS+M E
Sbjct: 219 FSRDELLAMERELFATVGYDLGSPLSYRYLRRFGRVCRVDMKTLTMGRFILETSLMVYEY 278
Query: 354 IAAPPSWLAAGAYYLSKIIIGLTG---WSDEHIYYSGYTEEQLIPL 396
S LAA A+ L+ ++ W+ YSG+T E+++PL
Sbjct: 279 AMVSQSRLAAAAFVLAMRMLDKNNEYEWNPVLEKYSGFTGEEVMPL 324
>At5g25380 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 444
Score = 131 bits (329), Expect = 2e-30
Identities = 80/264 (30%), Positives = 139/264 (52%), Gaps = 11/264 (4%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRY-IEHQPELTWKYRSTLIDWIVQVHDR 232
D DP S Y I++ + E + P+ Y ++ Q ++ R LIDW+V+V +
Sbjct: 168 DSGVQDPQFCSLYAASIYDSINVAELEQRPSTSYMVQVQRDIDPTMRGILIDWLVEVSEE 227
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
++L+ +TL+LTVN+IDRF+S + +LQL+G + IASKYEEI+ P L++ ++ DN
Sbjct: 228 YKLVSDTLYLTVNLIDRFMSHNYIEKQKLQLLGITCMLIASKYEEISAPRLEEFCFITDN 287
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYE-----YDTRTVAKYLLETS 347
YTR E+L E ++N+L+F P +FLRR +A + +A Y E +
Sbjct: 288 TYTRLEVLSMEIKVLNSLHFRLSVPTTKTFLRRFIRAAQASDKVPLIEMEYLANYFAELT 347
Query: 348 IMEPEIIAAPPSWLAAGAYYLSKIIIGLTG--WSDEHIYYSGYTEEQLIPLATMILDSCR 405
+ E + PS +AA A +L++ + + W+ +Y+ Y E + + ++ +
Sbjct: 348 LTEYTFLRFLPSLIAASAVFLARWTLDQSNHPWNQTLQHYTRY-ETSALKNTVLAMEELQ 406
Query: 406 HATERHK--AIFDKYSRSRHRKSA 427
T AI KY++ + ++ A
Sbjct: 407 LNTSGSTLIAIHTKYNQQKFKRVA 430
>At1g15570 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 450
Score = 130 bits (326), Expect = 5e-30
Identities = 75/228 (32%), Positives = 124/228 (53%), Gaps = 8/228 (3%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDR 232
D D DP++ Y EI +L+ E K P P ++E Q ++T R L+DW+V+V +
Sbjct: 176 DSDDKDPLLCCLYAPEIHYNLRVSELKRRPLPDFMERIQKDVTQSMRGILVDWLVEVSEE 235
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
+ L +TL+LTV +ID FL V +LQL+G + IASKYEEI+ P +++ ++ DN
Sbjct: 236 YTLASDTLYLTVYLIDWFLHGNYVQRQQLQLLGITCMLIASKYEEISAPRIEEFCFITDN 295
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDY-----EYDTRTVAKYLLETS 347
YTR+++L E ++ +F+ P P +FLRR +A + +A YL E +
Sbjct: 296 TYTRDQVLEMENQVLKHFSFQIYTPTPKTFLRRFLRAAQASRLSPSLEVEFLASYLTELT 355
Query: 348 IMEPEIIAAPPSWLAAGAYYLSKIIIGLTG--WSDEHIYYSGYTEEQL 393
+++ + PS +AA A +L+K + + W+ +Y+ Y L
Sbjct: 356 LIDYHFLKFLPSVVAASAVFLAKWTMDQSNHPWNPTLEHYTTYKASDL 403
>At5g11300 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 434
Score = 127 bits (319), Expect = 3e-29
Identities = 74/226 (32%), Positives = 126/226 (55%), Gaps = 6/226 (2%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDR 232
D + DP S Y +I++++ E + P Y+E Q ++ R LIDW+V+V D
Sbjct: 160 DSNVEDPQCCSLYAADIYDNIHVAELQQRPLANYMELVQRDIDPDMRKILIDWLVEVSDD 219
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
++L+P+TL+LTVN+IDRFLS + RLQL+G + + IASKYEE++ P +++ ++ N
Sbjct: 220 YKLVPDTLYLTVNLIDRFLSNSYIERQRLQLLGVSCMLIASKYEELSAPGVEEFCFITAN 279
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYE---YDTRTVAKYLLETSIM 349
YTR E+L E ++N ++F P +FL + + + +A YL E +++
Sbjct: 280 TYTRPEVLSMEIQILNFVHFRLSVPTTKTFLSALFLIIILQVPFIELEYLANYLAELTLV 339
Query: 350 EPEIIAAPPSWLAAGAYYLSKIIIGLTG--WSDEHIYYSGYTEEQL 393
E + PS +AA A +L++ + T W+ +Y+ Y +L
Sbjct: 340 EYSFLRFLPSLIAASAVFLARWTLDQTDHPWNPTLQHYTRYEVAEL 385
>CE06570 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 361
Score = 117 bits (294), Expect = 3e-26
Identities = 68/191 (35%), Positives = 115/191 (59%), Gaps = 11/191 (5%)
Query: 189 EIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIID 248
+I+++L E+K+ ++E E T K R L+DW+VQVH RF L PETL LTV I+D
Sbjct: 81 DIYKYLVHHEKKYLLEECFMEGG-EPTPKMRRILVDWLVQVHVRFHLTPETLHLTVFILD 139
Query: 249 RFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMIN 308
R L KK + LQL+G +A+F+ASK+EE+ P + D ++ +N Y++++IL E+ ++N
Sbjct: 140 RMLQKKVTSKADLQLLGISAMFVASKFEEVYLPDIHDYEFITENTYSKKQILAMEQTILN 199
Query: 309 TLNFEFGWPGPMSFLRRVSKA----DDYEYD------TRTVAKYLLETSIMEPEIIAAPP 358
+LNF+ P + FLR +S+ D D T ++K L E ++++ + + P
Sbjct: 200 SLNFDLSCPSSLVFLRCLSRILSENDASPIDNQAFCYTYNISKCLGELALLDSVMASTPR 259
Query: 359 SWLAAGAYYLS 369
S +A+ + ++
Sbjct: 260 SHIASASMIIA 270
>CE28122 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 317
Score = 115 bits (287), Expect = 2e-25
Identities = 78/278 (28%), Positives = 147/278 (52%), Gaps = 21/278 (7%)
Query: 170 PDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQV 229
P N E+ + + ++E +I+ +L E+K+ + +I + + K R L+DW++QV
Sbjct: 18 PRTNLEEVLNCIAMAE---DIYNYLVHHEKKYVLDDSFI-NGGNVNSKMRRILVDWLIQV 73
Query: 230 HDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYM 289
H RF L PETL LT+ ++DR + K V+ QL+G AALF+ASK+E+I P + + +
Sbjct: 74 HLRFHLTPETLHLTIFVLDRIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYEMI 133
Query: 290 LDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKA----------DDYEYDTRTV 339
DN +++++I+ E+ ++N LNF+ P + FLR +SK + Y +
Sbjct: 134 TDNTFSKKQIMAMEQTILNALNFDLSCPSSLVFLRCISKTLTENDVNPIDKEAFYYVHNI 193
Query: 340 AKYLLETSIMEPEIIAAPPSWLAAGAYYLSKIIIGLTGWSDE----HIYYSGYTEEQLIP 395
+K L E ++++ + P S +A+ + ++ +I + G + + I +Q I
Sbjct: 194 SKCLGELALLDSVMSTVPRSHVASASMIITLNVITVDGINPKTAASMIRKQLGASKQDIY 253
Query: 396 LATMILDSCRHATERHK---AIFDKYSRSRHRKSAFVV 430
A +L + RH+ AI +KY S+ + ++++
Sbjct: 254 DAIALLAQVAYKNFRHQKLCAIREKYQSSKFGRVSYLM 291
>CE23835 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 339
Score = 115 bits (287), Expect = 2e-25
Identities = 76/259 (29%), Positives = 138/259 (52%), Gaps = 18/259 (6%)
Query: 189 EIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIID 248
+I+ +L E+K+ + +I + + K R L+DW+VQVH RF L PETL LT+ ++D
Sbjct: 56 DIYNYLVHHEKKYVLDDSFI-NGGNVNSKMRRILVDWLVQVHLRFHLTPETLHLTIFVLD 114
Query: 249 RFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMIN 308
R + K V+ QL+G AALF+ASK+E+I P + + + +N +++++IL E+ ++N
Sbjct: 115 RIIVKNIVSKAEFQLLGVAALFVASKFEDIYLPDILEYELITENTFSKKQILAMEQTILN 174
Query: 309 TLNFEFGWPGPMSFLRRVSKA----------DDYEYDTRTVAKYLLETSIMEPEIIAAPP 358
LNF+ P + FLR +SK + Y ++K L E ++++ + P
Sbjct: 175 ALNFDLSCPSSLVFLRYISKTLTENDVNPIDKETFYYVHNISKCLGELALLDSVMSTVPR 234
Query: 359 SWLAAGAYYLSKIIIGLTGWSDE----HIYYSGYTEEQLIPLATMILDSCRHATERHK-- 412
S +A+ + ++ II + G + + I +Q I A +L + RH+
Sbjct: 235 SHVASASMIITLNIISVDGINPKTAASMIRKQFGASKQDIYDAISLLAQVAYKNFRHQKL 294
Query: 413 -AIFDKYSRSRHRKSAFVV 430
AI +KY S+ + ++++
Sbjct: 295 CAIREKYQSSKFGRVSYLM 313
>At1g20590 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 199
Score = 110 bits (275), Expect = 4e-24
Identities = 63/182 (34%), Positives = 101/182 (54%), Gaps = 7/182 (3%)
Query: 250 FLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINT 309
FL+ Q+ +LQLVG AL +A KYEE++ P + D++ + D AY+R E+L E+ M NT
Sbjct: 3 FLAVHQIVRKKLQLVGVTALLLACKYEEVSVPVVDDLILISDKAYSRREVLDMEKLMANT 62
Query: 310 LNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGAYYLS 369
L F F P P F++R KA + ++ +++E ++E E++ PS LAA A Y +
Sbjct: 63 LQFNFSLPTPYVFMKRFLKAAQSDKKLEILSFFMIELCLVEYEMLEYLPSKLAASAIYTA 122
Query: 370 KIII-GLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATERHKAIFDKYSRSRHRKSAF 428
+ + G WS +++GY EEQL+ A ++ HKA K + S S+F
Sbjct: 123 QCTLKGFEEWSKTCEFHTGYNEEQLLACARKMV------AFHHKAGTGKLTGSTTHLSSF 176
Query: 429 VV 430
++
Sbjct: 177 ML 178
>Hs16306525_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 221
Score = 103 bits (256), Expect = 7e-22
Identities = 67/212 (31%), Positives = 111/212 (51%), Gaps = 5/212 (2%)
Query: 233 FQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDN 292
F++ ETL+L V ++D +L K ++LQL+GA A IA+K+EE N P + D +Y+ D+
Sbjct: 1 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 60
Query: 293 AYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPE 352
Y R E+L E ++N L + P FLRR ++ T T+++Y+ E ++ E
Sbjct: 61 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 120
Query: 353 IIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHAT-ERH 411
+ S LAA + L+ + L W +YSGY+ +L PL + ++ +
Sbjct: 121 YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDSL 180
Query: 412 KAIFDKYSRSRHRKSAFVVAKWISMAESRLEQ 443
KA++ KYS F VAK ++ +LE+
Sbjct: 181 KAVYYKYS----HPVFFEVAKIPALDMLKLEE 208
>CE03820 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 485
Score = 102 bits (253), Expect = 1e-21
Identities = 69/251 (27%), Positives = 118/251 (46%), Gaps = 7/251 (2%)
Query: 185 EYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTV 244
E+ +I +++ + K + + Q ++ + R+ LIDW V + ET L V
Sbjct: 211 EFFPDIIKYMLHRQTKNRASHECFDIQSQVNEEMRTILIDWFSDVVKEYNFQKETFHLAV 270
Query: 245 NIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAER 304
+++DR LS + R QLVG ++ IA KYEEI P ++D + DN Y +IL ER
Sbjct: 271 SLVDRALSMFNIDKMRFQLVGTTSMMIAVKYEEIFPPEIEDFALITDNTYRVPDILLMER 330
Query: 305 FMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAG 364
F++ +F P F +K ++ R YLLE S+++ + PS +AA
Sbjct: 331 FLLGKFDFVVAMPTSSWFGTCFAKRMNFTKKMRNTVHYLLELSLIDVHFLRYRPSDIAAA 390
Query: 365 AYYLSKIIIGLTGWSDEHIYYSGYTEEQLI----PLATMILDSCRHATERHKAIFDKYSR 420
A + + + W + + +G + E + L M L++ +T K+IF YS
Sbjct: 391 ACCFANLQADVESWPQKMVDDTGISTEDFVDVLRDLHRMYLNA---STADFKSIFYNYSE 447
Query: 421 SRHRKSAFVVA 431
+ + A + A
Sbjct: 448 TAQMEVALLPA 458
>SPBC19F5.01c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 359
Score = 93.6 bits (231), Expect = 5e-19
Identities = 47/143 (32%), Positives = 82/143 (56%), Gaps = 2/143 (1%)
Query: 183 VSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFL 242
+ EY +I HL E+ F N QPEL W R L+++IV++H+ F L +TL L
Sbjct: 93 LGEYQEDIIHHLITREKNFLLNVHLSNQQPELRWSMRPALVNFIVEIHNGFDLSIDTLPL 152
Query: 243 TVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEI--NCPTLKDMLYMLDNAYTREEIL 300
+++++D ++S++ V +QLV L+IASK+ E P L+++ N Y + +
Sbjct: 153 SISLMDSYVSRRVVYCKHIQLVACVCLWIASKFHETEDRVPLLQELKLACKNIYAEDLFI 212
Query: 301 RAERFMINTLNFEFGWPGPMSFL 323
R ER +++TL+++ P P S++
Sbjct: 213 RMERHILDTLDWDISIPTPASYI 235
>Hs4502621 [D] KOG0654 G2/Mitotic-specific cyclin A
Length = 786
Score = 85.1 bits (209), Expect = 2e-16
Identities = 52/189 (27%), Positives = 95/189 (49%), Gaps = 1/189 (0%)
Query: 219 RSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEI 278
R LIDW+V+V L LTV +DR+L ++ V RLQL+G A + I +++
Sbjct: 310 RYILIDWLVEVATMNDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISK 369
Query: 279 NCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRT 338
T+++ +++ DN Y E+++R +++ L + P + + + E T+
Sbjct: 370 EILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQH 429
Query: 339 VAKYLLETSIMEPEIIAAPPSWLAAGAYYLSKIIIGLT-GWSDEHIYYSGYTEEQLIPLA 397
+ +L E S++ + A P+ LAA A L+++ G T W+ + +G++ E LIP
Sbjct: 430 LCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489
Query: 398 TMILDSCRH 406
+ C H
Sbjct: 490 LSLHKKCFH 498
>Hs17318565 [D] KOG0655 G1/S-specific cyclin E
Length = 404
Score = 83.6 bits (205), Expect = 5e-16
Identities = 53/171 (30%), Positives = 90/171 (51%), Gaps = 8/171 (4%)
Query: 144 TPLVPVVTEHSERLYQYVYERLHREEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSP 203
TP + T R Y ++ L P P + +W + E++ ++ E ++
Sbjct: 74 TPHKEIGTSDFSRFTNYRFKNLFIN-PSPLPDLSWG------CSKEVWLNMLKKESRYVH 126
Query: 204 NPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRF-LSKKQVTLNRLQ 262
+ + +L + RS L+DW+++V + + L ET +L + DRF L++K + N LQ
Sbjct: 127 DKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQ 186
Query: 263 LVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFE 313
L+G +LFIASK EEI P L++ Y+ D A + E+ILR E ++ L +E
Sbjct: 187 LIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWE 237
>Hs17318567 [D] KOG0655 G1/S-specific cyclin E
Length = 296
Score = 81.6 bits (200), Expect = 2e-15
Identities = 44/126 (34%), Positives = 75/126 (58%), Gaps = 1/126 (0%)
Query: 189 EIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIID 248
E++ ++ E ++ + + +L + RS L+DW+++V + + L ET +L + D
Sbjct: 4 EVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFD 63
Query: 249 RF-LSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMI 307
RF L++K + N LQL+G +LFIASK EEI P L++ Y+ D A + E+ILR E ++
Sbjct: 64 RFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIIL 123
Query: 308 NTLNFE 313
L +E
Sbjct: 124 KALKWE 129
>Hs22048740 [D] KOG0655 G1/S-specific cyclin E
Length = 148
Score = 80.9 bits (198), Expect = 4e-15
Identities = 41/96 (42%), Positives = 62/96 (63%), Gaps = 1/96 (1%)
Query: 219 RSTLIDWIVQVHDRFQLLPETLFLTVNIIDRF-LSKKQVTLNRLQLVGAAALFIASKYEE 277
RS L+DW+++V + + L ET +L + DRF L++K + N LQL+G +LFIASK EE
Sbjct: 2 RSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEE 61
Query: 278 INCPTLKDMLYMLDNAYTREEILRAERFMINTLNFE 313
I P L++ Y+ D A + E+ILR E ++ L +E
Sbjct: 62 IYAPKLQEFAYVTDGACSEEDILRMELIILKALKWE 97
>At1g34460_1 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 399
Score = 79.7 bits (195), Expect = 8e-15
Identities = 50/153 (32%), Positives = 79/153 (50%), Gaps = 21/153 (13%)
Query: 171 DPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVH 230
D ++ D + V EY +++ K +E++ P Y+ Q E+ K R+ LIDW+++VH
Sbjct: 257 DIDESDKDNHVAAVEYVDDMYSFYKEVEKESQPK-MYMHIQTEMNEKMRAILIDWLLEVH 315
Query: 231 DRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYML 290
+F+L ETL+LTVNIIDRFL K V LQ + D++Y+
Sbjct: 316 IKFELNLETLYLTVNIIDRFLYVKAVPKRELQ--------------------VNDLVYVT 355
Query: 291 DNAYTREEILRAERFMINTLNFEFGWPGPMSFL 323
DNAY+ +IL ++ ++ L + P FL
Sbjct: 356 DNAYSSRQILVMKKAILGNLEWYLTIPTQYVFL 388
>Hs17318561 [D] KOG0655 G1/S-specific cyclin E
Length = 395
Score = 77.4 bits (189), Expect = 4e-14
Identities = 55/200 (27%), Positives = 101/200 (50%), Gaps = 12/200 (6%)
Query: 180 PVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPET 239
PV+ E+++ + E+ + + ++E P L K R+ L+DW+++V + ++L ET
Sbjct: 91 PVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRET 150
Query: 240 LFLTVNIIDRFLSKKQ-VTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREE 298
+L + DR+++ ++ V LQL+G ++LFIA+K EEI P L Y+ D A + +E
Sbjct: 151 FYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDE 210
Query: 299 ILRAERFMINTLNFEFGWPGPMSFLR---RVSKADD--------YEYDTRTVAKYLLETS 347
IL E ++ L + +S+L +V+ +D Y LL+
Sbjct: 211 ILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLC 270
Query: 348 IMEPEIIAAPPSWLAAGAYY 367
+++ + + P LAA A Y
Sbjct: 271 VLDVDCLEFPYGILAASALY 290
>Hs17318559 [D] KOG0655 G1/S-specific cyclin E
Length = 410
Score = 77.4 bits (189), Expect = 4e-14
Identities = 55/200 (27%), Positives = 101/200 (50%), Gaps = 12/200 (6%)
Query: 180 PVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPET 239
PV+ E+++ + E+ + + ++E P L K R+ L+DW+++V + ++L ET
Sbjct: 106 PVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRET 165
Query: 240 LFLTVNIIDRFLSKKQ-VTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREE 298
+L + DR+++ ++ V LQL+G ++LFIA+K EEI P L Y+ D A + +E
Sbjct: 166 FYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDE 225
Query: 299 ILRAERFMINTLNFEFGWPGPMSFLR---RVSKADD--------YEYDTRTVAKYLLETS 347
IL E ++ L + +S+L +V+ +D Y LL+
Sbjct: 226 ILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLC 285
Query: 348 IMEPEIIAAPPSWLAAGAYY 367
+++ + + P LAA A Y
Sbjct: 286 VLDVDCLEFPYGILAASALY 305
>7298245 [D] KOG0655 G1/S-specific cyclin E
Length = 709
Score = 76.6 bits (187), Expect = 7e-14
Identities = 40/118 (33%), Positives = 68/118 (56%), Gaps = 7/118 (5%)
Query: 208 IEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLS-KKQVTLNRLQLVGA 266
+E P L + R+ L+DW+++V + ++L ET +L V+ +DR+L +V LQL+G
Sbjct: 351 LEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGI 410
Query: 267 AALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEF------GWPG 318
LF+A+K EEI P + + Y+ D A T +IL E+ ++ L+++ GW G
Sbjct: 411 TCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLG 468
>Hs16950655 [D] KOG0656 G1/S-specific cyclin D
Length = 295
Score = 75.5 bits (184), Expect = 1e-13
Identities = 50/173 (28%), Positives = 89/173 (50%), Gaps = 5/173 (2%)
Query: 198 ERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQV 256
E +P+ Y + Q E+ R + W+++V + + E L +N +DRFLS + V
Sbjct: 35 EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94
Query: 257 TLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGW 316
+RLQL+GA +F+ASK +E T + + DN+ EE+L+ E ++N L +
Sbjct: 95 KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAA 154
Query: 317 PGPMS----FLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGA 365
P FL ++ +A++ + R A+ + + + I+ PPS +AAG+
Sbjct: 155 MTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGS 207
>7293153 [D] KOG0656 G1/S-specific cyclin D
Length = 481
Score = 74.7 bits (182), Expect = 3e-13
Identities = 49/175 (28%), Positives = 88/175 (50%), Gaps = 4/175 (2%)
Query: 151 TEHSERLYQYVYERLHREEPDPNDEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH 210
T H +RL + + D + DP + S+ +E F LK E+ Y
Sbjct: 120 TSHCQRLDERLTTTADPPATDNVNTAIGDPTLYSDRCLENF--LKVEEKHHKIPDTYFSI 177
Query: 211 QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALF 270
Q ++T R + +W+++V E + L +N +DRFLS K V +LQ++ AA L
Sbjct: 178 QKDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRFLSSKSVRKTQLQILAAACLL 237
Query: 271 IASKYEEINCPTLK-DMLYM-LDNAYTREEILRAERFMINTLNFEFGWPGPMSFL 323
+ASK E +C L D+L + DN+ ++++++ E ++++ L ++ P+ FL
Sbjct: 238 LASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFL 292
>HsM4502615 [D] KOG0656 G1/S-specific cyclin D
Length = 295
Score = 73.9 bits (180), Expect = 4e-13
Identities = 49/173 (28%), Positives = 89/173 (51%), Gaps = 5/173 (2%)
Query: 198 ERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQV 256
E +P+ Y + Q E+ R + W+++V + + E L +N +DRFLS + V
Sbjct: 35 EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94
Query: 257 TLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGW 316
+RLQL+GA +F+ASK +E T + + D + EE+L+ E ++N L +
Sbjct: 95 KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDGSIRPEELLQMELLLVNKLKWNLAA 154
Query: 317 PGPMS----FLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGA 365
P FL ++ +A++ + R A+ + + + + I+ PPS +AAG+
Sbjct: 155 MTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVASCATDVKFISNPPSMVAAGS 207
>CE24832 [D] KOG0655 G1/S-specific cyclin E
Length = 524
Score = 72.8 bits (177), Expect = 1e-12
Identities = 49/149 (32%), Positives = 79/149 (52%), Gaps = 19/149 (12%)
Query: 210 HQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQV--TLNRLQLVGAA 267
+ P++ + R LIDW+++V + +L ET L V+ +DR+L V + + QLVG A
Sbjct: 253 NHPDMDDEKRRILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTA 312
Query: 268 ALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGWP-GPMSFLRRV 326
ALFIA+KYEEI P D ++ D+A+T + I E ++ + GW GP++ ++ +
Sbjct: 313 ALFIAAKYEEIYPPKCIDFAHLTDSAFTCDNIRTMEVLIVKYI----GWSLGPITSIQWL 368
Query: 327 S------------KADDYEYDTRTVAKYL 343
S K+D YE V + L
Sbjct: 369 STYLQLLGTGKKNKSDHYEEQNMYVPELL 397
>ECU09g1030 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 216
Score = 69.3 bits (168), Expect = 1e-11
Identities = 48/161 (29%), Positives = 78/161 (47%), Gaps = 4/161 (2%)
Query: 218 YRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEE 277
+R L+ W+ +V D F T V I+DR+ + + L + QLVG +ALF+++K EE
Sbjct: 34 HRRKLVQWLYEVTDDFGYSQVTFSTAVFILDRYTEARGLDLEKYQLVGISALFLSAKIEE 93
Query: 278 INCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMSFL--RRVSKADD-YEY 334
C + D +++ D A + +EIL E M+ +F P SFL R + KA D Y
Sbjct: 94 KWCKAVDDYVHVTDGACSGKEILDKEIEMLEVFDFNMMLRLPHSFLQERYLEKASDKYTM 153
Query: 335 DTRTVAKYLLETSIMEPEIIAAPPSWL-AAGAYYLSKIIIG 374
R + + ++E I + W+ G K++ G
Sbjct: 154 KQRQEIFFCAFSYVIEKNICGSSMYWIYLEGVKEAEKVLSG 194
>CE21610 [D] KOG0656 G1/S-specific cyclin D
Length = 405
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/179 (28%), Positives = 80/179 (44%), Gaps = 8/179 (4%)
Query: 198 ERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQV 256
E PN Y Q +T +R IDWI V + L V++IDRF+S + +
Sbjct: 83 EEALQPNYHYFTGVQENITPFHREQAIDWIYDVAKEENCDGDVFLLAVSLIDRFMSVQNI 142
Query: 257 TLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGW 316
+ +Q++ ALFIASK + + T + Y DN+ + IL+ E ++ TL +E
Sbjct: 143 LKHDIQMIAGVALFIASKLKAPHPMTASKIAYYSDNSCPIDMILQWELLIVTTLQWETES 202
Query: 317 PGPMSFL----RRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGAYYLSKI 371
P SF R+ + + D +TV + + M P A G YY+S +
Sbjct: 203 PTAFSFFDFLASRIPQIHNMRGDFQTVVQ---KCQKMHKLATLFPSMQCAIGLYYVSNL 258
>Hs22062947 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 403
Score = 66.2 bits (160), Expect = 9e-11
Identities = 36/129 (27%), Positives = 72/129 (54%), Gaps = 3/129 (2%)
Query: 304 RFMINTLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAA 363
+ ++ L FE G P P+ FLR+ SKA + + T+AKYL+E ++++ +++ PS A
Sbjct: 256 KLILKELKFEVGGPLPLHFLRQASKAGKADVEQHTLAKYLMELTLIDYDMMHYHPSKAAT 315
Query: 364 GAYYLSKIIIGLTGWSDEHIYYSGYTEEQLIPLATMILDSCRHATE---RHKAIFDKYSR 420
A LS+ ++G W+ + Y+GYT+ +++ + + + E + AI +KY+
Sbjct: 316 AASCLSQKVLGQGKWNLKQQCYTGYTQNEVLEVMQHVAKNVLKVNENLTKFIAIKNKYAS 375
Query: 421 SRHRKSAFV 429
++ K + +
Sbjct: 376 NKFLKISMI 384
>Hs4502617 [D] KOG0656 G1/S-specific cyclin D
Length = 289
Score = 60.5 bits (145), Expect = 5e-09
Identities = 41/181 (22%), Positives = 86/181 (46%), Gaps = 5/181 (2%)
Query: 190 IFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIID 248
+ ++L +E ++ P Y + Q ++ R + W+++V + + E L +N +D
Sbjct: 26 VLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLD 85
Query: 249 RFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTREEILRAERFMIN 308
RFL+ + LQL+GA +F+ASK +E + T + + DN+ +E+L E ++
Sbjct: 86 RFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLG 145
Query: 309 TLNFEFGWPGPMSFLRRVSKADDYEYDTRTVAKYLLETSI----MEPEIIAAPPSWLAAG 364
L + P F+ + + + + ++ + +T I + + PPS +A G
Sbjct: 146 KLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATG 205
Query: 365 A 365
+
Sbjct: 206 S 206
>At1g14750_2 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 281
Score = 57.0 bits (136), Expect = 6e-08
Identities = 57/176 (32%), Positives = 84/176 (47%), Gaps = 22/176 (12%)
Query: 217 KYRSTLIDWIVQVHDRFQ----LLP-------------ETLFLTVNIIDRFLSKKQVTLN 259
+ RS ++ WIV+ F LLP ETLFL V ++DRFLSK
Sbjct: 52 RLRSIMVQWIVKSAMIFFVADCLLPDYKQQCSDMGLQQETLFLGVGLLDRFLSKGSFKSE 111
Query: 260 R-LQLVGAAALFIASKYEEINCP--TLKDMLYMLDNA-YTREEILRAERFMINTLNFEFG 315
R L LVG A+L +A++ EE N P +++ + + N Y+R E++ E + LNF+
Sbjct: 112 RTLILVGIASLTLATRIEE-NQPYNSIRKRNFTIQNLRYSRHEVVAMEWLVQEVLNFKCF 170
Query: 316 WPGPMSFLRRVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGAYYLSKI 371
P +FL KA + AK L TS+ + + PS +AA L+ I
Sbjct: 171 TPTIFNFLWFYLKAARANPEVERKAKSLAVTSLSDQTQLCFWPSTVAAALVVLACI 226
>YAL040c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 580
Score = 56.2 bits (134), Expect = 9e-08
Identities = 38/134 (28%), Positives = 65/134 (48%), Gaps = 4/134 (2%)
Query: 183 VSEYTIEIFEHLKFLERKFSP--NPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETL 240
+SEY + +H L P N QP++ K R + D+I+ H R L TL
Sbjct: 70 ISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTSTL 129
Query: 241 FLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKY--EEINCPTLKDMLYMLDNAYTREE 298
FLT I+D++ S+ + QL+ AL+I+SK+ + TLK + + N Y+ ++
Sbjct: 130 FLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQ 189
Query: 299 ILRAERFMINTLNF 312
E + +L++
Sbjct: 190 FTTMEMHLFKSLDW 203
>Hs5802992 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 377
Score = 55.8 bits (133), Expect = 1e-07
Identities = 34/122 (27%), Positives = 60/122 (48%), Gaps = 2/122 (1%)
Query: 204 NPRYIEHQPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNRLQL 263
N R + ++ R +I W+ ++ +F L PET L +++DRFL+ + L
Sbjct: 30 NVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSC 89
Query: 264 VGAAALFIASK--YEEINCPTLKDMLYMLDNAYTREEILRAERFMINTLNFEFGWPGPMS 321
+ + F+A+K E+ P LK + + EILR ER +++ LN++ P+
Sbjct: 90 IAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLD 149
Query: 322 FL 323
FL
Sbjct: 150 FL 151
>At5g10440 [D] KOG0656 G1/S-specific cyclin D
Length = 317
Score = 55.1 bits (131), Expect = 2e-07
Identities = 48/194 (24%), Positives = 88/194 (44%), Gaps = 17/194 (8%)
Query: 189 EIFEHLKFLERKFSPNPRYIEH--QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNI 246
EI + ER+ SP Y++ +L + R + WI + + Q P + L +N
Sbjct: 37 EIVREMIEKERQHSPRDDYLKRLRNGDLDFNVRIQALGWIWKACEELQFGPLCICLAMNY 96
Query: 247 IDRFLSKKQVTLNR---LQLVGAAALFIASKYEEINCPTLKDMLYMLDN-AYTREEILRA 302
+DRFLS + + +QL+ A L +A+K EE N P L + + + + R
Sbjct: 97 LDRFLSVHDLPSGKAWTVQLLAVACLSLAAKIEETNVPELMQLQVGAPMFVFEAKSVQRM 156
Query: 303 ERFMINTLNFEFGWPGPMSFLRR-VSKADDYEYD--TRTVAKYLLETSIMEPEIIAAPPS 359
E ++N L + P S++R +SK + Y+ + +R V + L ++IA+
Sbjct: 157 ELLVLNVLRWRLRAVTPCSYVRYFLSKINGYDQEPHSRLVTRSL--------QVIASTTK 208
Query: 360 WLAAGAYYLSKIII 373
G ++ ++I
Sbjct: 209 GDRLGLFFFKGVLI 222
>At3g50070 [D] KOG0656 G1/S-specific cyclin D
Length = 361
Score = 55.1 bits (131), Expect = 2e-07
Identities = 48/178 (26%), Positives = 83/178 (45%), Gaps = 15/178 (8%)
Query: 219 RSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNR---LQLVGAAALFIASKY 275
R +DWI +V + T L VN DRF++ ++ ++ QL A L +A+K
Sbjct: 86 REKALDWIFKVKSHYGFNSLTALLAVNYFDRFITSRKFQTDKPWMSQLTALACLSLAAKV 145
Query: 276 EEINCPTLKDMLYMLDNA---YTREEILRAERFMINTLNFEFGWPGPMSF----LRRVSK 328
EEI P L D + ++ A + + I R E +++TL++ P+SF +RR S
Sbjct: 146 EEIRVPFLLD--FQVEEARYVFEAKTIQRMELLVLSTLDWRMHPVTPISFFDHIIRRYSF 203
Query: 329 ADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGAYYLSKIIIGLTGWSDEHIYYS 386
++ + + + LL + I + ++ PS LA + +I DE +Y S
Sbjct: 204 KSHHQLEFLSRCESLLLSIIPDSRFLSFSPSVLATA---IMVSVIRDLKMCDEAVYQS 258
>Hs4502619 [D] KOG0656 G1/S-specific cyclin D
Length = 292
Score = 54.7 bits (130), Expect = 3e-07
Identities = 46/192 (23%), Positives = 85/192 (43%), Gaps = 7/192 (3%)
Query: 179 DPVMVSEYTIEIFEHLKFLERKFSPNPRYIEH-QPELTWKYRSTLIDWIVQVHDRFQLLP 237
DP ++ + + + L LE ++ P Y + Q E+ R L W+++V + +
Sbjct: 18 DPRLLGDQ--RVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEE 75
Query: 238 ETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTRE 297
E L +N +DR+LS +LQL+GA + +ASK E T++ + D+A +
Sbjct: 76 EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR 135
Query: 298 EILRAERFMINTLNFEFGWPGPMSF----LRRVSKADDYEYDTRTVAKYLLETSIMEPEI 353
++ E ++ L ++ F L R+S D + + A+ L +
Sbjct: 136 QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTF 195
Query: 354 IAAPPSWLAAGA 365
PPS +A G+
Sbjct: 196 AMYPPSMIATGS 207
>Hs20541478 [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 153
Score = 54.7 bits (130), Expect = 3e-07
Identities = 36/122 (29%), Positives = 60/122 (48%), Gaps = 12/122 (9%)
Query: 174 DEDTWDPVMVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELTWKYRSTLIDWIVQVHDRF 233
D+D DP S YT EI ++ E K Q ++ R L+DW+ ++ F
Sbjct: 42 DKDLSDPFFNSIYTKEISSYMNLREEK----------QTDINSVMRVILVDWLGKMQISF 91
Query: 234 QLLPETLFLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASKYEEINCPT-LKDMLYMLDN 292
++ ETL L + + + + + LQL+G A +A+K+EE CP+ + D+LY+
Sbjct: 92 EMTQETLSLVLKPVYHYFMEVVCKKDGLQLLGPTAFLMAAKFEE-PCPSFVDDLLYLCGG 150
Query: 293 AY 294
Y
Sbjct: 151 IY 152
>At5g67260 [D] KOG0656 G1/S-specific cyclin D
Length = 367
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/160 (27%), Positives = 74/160 (45%), Gaps = 12/160 (7%)
Query: 219 RSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQVTLNR---LQLVGAAALFIASKY 275
R +DW+++V + T L VN DRF++ ++ ++ QLV A+L +A+K
Sbjct: 96 RKEALDWVLRVKSHYGFTSLTAILAVNYFDRFMTSIKLQTDKPWMSQLVAVASLSLAAKV 155
Query: 276 EEINCPTLKDMLYMLDNA---YTREEILRAERFMINTLNFEFGWPGPMSF----LRRVSK 328
EEI P L D+ ++ A + + I R E +++TL + P+SF +RR
Sbjct: 156 EEIQVPLLLDL--QVEEARYLFEAKTIQRMELLILSTLQWRMHPVTPISFFDHIIRRFGS 213
Query: 329 ADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGAYYL 368
+ D + LL + I + + PS LA L
Sbjct: 214 KWHQQLDFCRKCERLLISVIADTRFMRYFPSVLATAIMIL 253
>At2g22490 [D] KOG0656 G1/S-specific cyclin D
Length = 361
Score = 50.8 bits (120), Expect = 4e-06
Identities = 38/133 (28%), Positives = 67/133 (49%), Gaps = 8/133 (6%)
Query: 198 ERKFSPNPRYIEH--QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQ 255
E +F P Y++ +L R+ +DWI++V + + L++N +DRFL+ +
Sbjct: 74 EIEFCPGTDYVKRLLSGDLDLSVRNQALDWILKVCAHYHFGHLCICLSMNYLDRFLTSYE 133
Query: 256 VTLNR---LQLVGAAALFIASKYEEINCPTLKDMLYMLDNAYTRE--EILRAERFMINTL 310
+ ++ QL+ + L +ASK EE + P + D L + D + E I R E ++ TL
Sbjct: 134 LPKDKDWAAQLLAVSCLSLASKMEETDVPHIVD-LQVEDPKFVFEAKTIKRMELLVVTTL 192
Query: 311 NFEFGWPGPMSFL 323
N+ P SF+
Sbjct: 193 NWRLQALTPFSFI 205
>At1g70210 [D] KOG0656 G1/S-specific cyclin D
Length = 339
Score = 50.4 bits (119), Expect = 5e-06
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 10/178 (5%)
Query: 198 ERKFSPNPRYIEH--QPELTWKYRSTLIDWIVQVHDRFQLLPETLFLTVNIIDRFLSKKQ 255
ER F P Y+ L R + WI++V + P T +L VN +DRFL ++
Sbjct: 59 ERHFVPGHDYLSRFQTRSLDASAREDSVAWILKVQAYYNFQPLTAYLAVNYMDRFLYARR 118
Query: 256 VTLNR---LQLVGAAALFIASKYEEINCPTLKD-MLYMLDNAYTREEILRAERFMINTLN 311
+ +QL+ A L +A+K EEI P+L D + + + + I R E +++ L+
Sbjct: 119 LPETSGWPMQLLAVACLSLAAKMEEILVPSLFDFQVAGVKYLFEAKTIKRMELLVLSVLD 178
Query: 312 FEFGWPGPMSFLR----RVSKADDYEYDTRTVAKYLLETSIMEPEIIAAPPSWLAAGA 365
+ P F+ ++ + + + A ++ ++I E + PS +AA A
Sbjct: 179 WRLRSVTPFDFISFFAYKIDPSGTFLGFFISHATEIILSNIKEASFLEYWPSSIAAAA 236
>YPL256c [D] KOG0653 Cyclin B and related kinase-activating proteins
Length = 545
Score = 49.7 bits (117), Expect = 9e-06
Identities = 30/94 (31%), Positives = 54/94 (56%), Gaps = 1/94 (1%)
Query: 182 MVSEYTIEIFEHLKFLERKFSPNPRYIEHQPELT-WKYRSTLIDWIVQVHDRFQLLPETL 240
M+ EY EI ++ KF PNP+ I+ QPE+ + RS +I ++ ++ ++
Sbjct: 36 MLQEYHQEISTNVIAQSCKFKPNPKLIDQQPEMNPVETRSNIITFLFELSVVTRVTNGIF 95
Query: 241 FLTVNIIDRFLSKKQVTLNRLQLVGAAALFIASK 274
F +V + DR+ SK+ V ++ +LV A L++A+K
Sbjct: 96 FHSVRLYDRYCSKRIVLRDQAKLVVATCLWLAAK 129
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,288,009
Number of Sequences: 60738
Number of extensions: 1070556
Number of successful extensions: 3232
Number of sequences better than 1.0e-05: 73
Number of HSP's better than 0.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3114
Number of HSP's gapped (non-prelim): 79
length of query: 444
length of database: 30,389,216
effective HSP length: 110
effective length of query: 334
effective length of database: 23,708,036
effective search space: 7918484024
effective search space used: 7918484024
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)