ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4159 good I KOG1737 Lipid transport and metabolism Oxysterol-binding protein
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4159 1466983 1469922 980
(980 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHR073w [I] KOG1737 Oxysterol-binding protein 644 0.0
Hs21735584 [I] KOG1737 Oxysterol-binding protein 215 3e-55
Hs21735582 [I] KOG1737 Oxysterol-binding protein 215 3e-55
Hs21735580 [I] KOG1737 Oxysterol-binding protein 215 3e-55
Hs14149704 [I] KOG1737 Oxysterol-binding protein 215 3e-55
Hs19718746 [T] KOG2209 Oxysterol-binding protein 213 2e-54
Hs19718741 [T] KOG2209 Oxysterol-binding protein 213 2e-54
Hs22035612 [I] KOG1737 Oxysterol-binding protein 209 1e-53
Hs14210532 [I] KOG1737 Oxysterol-binding protein 209 1e-53
HsM19923507 [I] KOG1737 Oxysterol-binding protein 208 4e-53
Hs22035614 [I] KOG1737 Oxysterol-binding protein 208 4e-53
Hs7662298 [T] KOG2209 Oxysterol-binding protein 200 8e-51
Hs21450853 [T] KOG2209 Oxysterol-binding protein 200 8e-51
At1g13170 [I] KOG1737 Oxysterol-binding protein 191 6e-48
At2g31020 [I] KOG1737 Oxysterol-binding protein 189 1e-47
At2g31030 [I] KOG1737 Oxysterol-binding protein 189 2e-47
7301240 [I] KOG1737 Oxysterol-binding protein 187 7e-47
At4g08180 [I] KOG1737 Oxysterol-binding protein 187 9e-47
SPAC23H4.01c [I] KOG1737 Oxysterol-binding protein 182 2e-45
At4g12460 [I] KOG1737 Oxysterol-binding protein 181 6e-45
CE23653 [T] KOG2209 Oxysterol-binding protein 178 4e-44
SPBC2F12.05c_2 [I] KOG1737 Oxysterol-binding protein 177 5e-44
YAR044w [I] KOG1737 Oxysterol-binding protein 172 2e-42
CE28126 [I] KOG1737 Oxysterol-binding protein 171 4e-42
CE26105 [I] KOG1737 Oxysterol-binding protein 171 4e-42
YDL019c [I] KOG1737 Oxysterol-binding protein 170 9e-42
At4g22540 [I] KOG1737 Oxysterol-binding protein 170 1e-41
Hs13540513 [I] KOG1737 Oxysterol-binding protein 166 2e-40
Hs4505531 [I] KOG1737 Oxysterol-binding protein 165 3e-40
Hs19718743 [T] KOG2209 Oxysterol-binding protein 161 5e-39
7291708 [T] KOG2209 Oxysterol-binding protein 154 8e-37
At5g02100 [I] KOG1737 Oxysterol-binding protein 137 8e-32
At3g09300 [I] KOG1737 Oxysterol-binding protein 130 1e-29
At5g59420 [I] KOG1737 Oxysterol-binding protein 126 2e-28
Hs22035609 [T] KOG2210 Oxysterol-binding protein 110 1e-23
Hs14149740 [T] KOG2210 Oxysterol-binding protein 110 1e-23
Hs18079218 [T] KOG2210 Oxysterol-binding protein 108 4e-23
CE06680 [T] KOG2210 Oxysterol-binding protein 99 4e-20
SPCC23B6.01c [T] KOG2210 Oxysterol-binding protein 94 1e-18
Hs22066714 [T] KOG2210 Oxysterol-binding protein 86 3e-16
YHR001w [T] KOG2210 Oxysterol-binding protein 71 7e-12
YKR003w [T] KOG2210 Oxysterol-binding protein 70 1e-11
YPL145c [T] KOG2210 Oxysterol-binding protein 62 3e-09
Hs21735588 [I] KOG1737 Oxysterol-binding protein 61 1e-08
Hs21735586 [I] KOG1737 Oxysterol-binding protein 61 1e-08
Hs19923812 [T] KOG2210 Oxysterol-binding protein 60 2e-08
CE08539 [T] KOG2210 Oxysterol-binding protein 60 2e-08
SPBC1271.12 [T] KOG2210 Oxysterol-binding protein 59 4e-08
At4g25850 [T] KOG2210 Oxysterol-binding protein 59 5e-08
YOR237w [T] KOG2210 Oxysterol-binding protein 58 6e-08
Hs20070331 [T] KOG2210 Oxysterol-binding protein 58 6e-08
7303831 [T] KOG2210 Oxysterol-binding protein 57 1e-07
>YHR073w [I] KOG1737 Oxysterol-binding protein
Length = 996
Score = 644 bits (1660), Expect = 0.0
Identities = 405/1065 (38%), Positives = 556/1065 (52%), Gaps = 154/1065 (14%)
Query: 1 MDTIDVQNKSFVVRWQKVSQGDIVSFRLKPLKKSIGFGIYRRFGGSSTTDLSETNHGSVK 60
M+TID+QN+SFVVRW K +GD++++++KPLKKSI GIY++ S+ D +H S
Sbjct: 1 METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKL--KSSVD----DHASA- 53
Query: 61 ASSNSNTNPLIRISTDAKPNVALADHEKDKNVPLQTRLAQSGLEKVTWYGTISNNDTVAE 120
+ I+ D K L D+ +S L K G+ SN +
Sbjct: 54 ----------VHIAPDTK---TLLDYT-----------TKSLLHK----GSSSNIE---- 81
Query: 121 SFESTCESCYYAFILDNTTSKQTKKKCLFSVSINPSASAMEGLDDDQESVISNQEESFGA 180
E S ++ N + + K++ S+SI+ G+ + + E A
Sbjct: 82 --EHHRRSSQHSHSSSNGSDNKRKERSYSSLSIS-------GIQQQSQEI--PLREKLSA 130
Query: 181 NG-TNGKRPLNYSQTSFKDPSLSSLAKSNSNPFA-----PSPGQTTPSTISNVGTSNGPN 234
+G T KR N S + L K +A S + N NG N
Sbjct: 131 SGFTLVKRVGNVSGNTMVQGDLE--VKDTDYYYAFILDNSSSKNAKKKILFNASVINGDN 188
Query: 235 -----TNSPVPIKPLSPSSTSATDHDLKNSKG----FQGYLLKKKRKKLQGFTKRFFKLD 285
T S P +P + S TS T D+ G QGYLLKK+RK+LQGF KRFF LD
Sbjct: 189 QSMISTRSTPPARPTALSRTS-TQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLD 247
Query: 286 IKFGILSYYLNSKSPVCRGEIVVPLSSISANKQTKLIIIDSGMEIWVMKARDEKDWELWI 345
++G LSYYLN + CRGEIV+ LSS+SANK+ K+IIIDSGME+WV+KA +++W+ W+
Sbjct: 248 FRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWV 307
Query: 346 SMIESCFK---QDAPTTS--------------------QDHE------------SH---- 366
+++CF +D T++ QDH+ SH
Sbjct: 308 DALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHT 367
Query: 367 -----NVVIP-PDNDTTAFFRNLTSLRKRIEECKYQSLSYSNYTPNAIVSPIQGPPTXXX 420
++ +P P F NL +++R+E+CK SLSY P + +G
Sbjct: 368 QKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYK---PTTLHQRSEGLNGTHS 424
Query: 421 XXXXXXXXXXXXXXXXXXXRQRNGSFVEQATSGHDTSILSNNPNEPQHHDLYRKLADLEK 480
+ S + + T I H LY +LADLE
Sbjct: 425 SSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYI---------EHALYNQLADLEV 475
Query: 481 IAKQLDIDGKML---------ATKWVPRSPTASIFSDDEYFDANEEP-----IITMLNDD 526
+ G++L K S T+ + +DE+FDA EE I+ DD
Sbjct: 476 FVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDD 535
Query: 527 VAFETDIRPIYSSYNDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPTSNELMT--- 583
+ + P+ + N
Sbjct: 536 INNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRR 595
Query: 584 ------STDRKTIETATSRSQDLSPLPINKTIKRRNDIAIPVSTPPSLLGFLRKNVGKDL 637
T T T S+DL L K++ RRNDI ++PPSLL FLRKNVGKDL
Sbjct: 596 GHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDL 655
Query: 638 SSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQK 697
SSI+MP++ NEP+SILQ++SE FEY+ LL+KA D + ++SAFA+S++SI+R K
Sbjct: 656 SSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDP----ITFVSAFAISFLSIYRDK 711
Query: 698 TRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKF 757
TR+LRKPF PLL ET+EL+REDMG RL+SEKV H+PP+FAF+ EH DW+CSYTVTP QKF
Sbjct: 712 TRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKF 771
Query: 758 WGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSISTSTNLKSI 817
WGKSIE NEG+ L F + W+QPT +LKN+IAGERYMEP N+F + +S KS
Sbjct: 772 WGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSH 831
Query: 818 IAFKAGGMFSGRSEDVDVSLV--NEKGQKLGSLKGQWTKEVRDLDNGQQIWKCGPLVENS 875
I F GMFSGRSE VS++ +K +L G+WT+ + + + IW+ G LV N
Sbjct: 832 ILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETTHETIWEVGDLVSNP 891
Query: 876 EKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRER 935
+KKYGFT FT+NLNEITE EK +LPPTDSRLRPDIR YE G + +AE+ KL LEQ QRER
Sbjct: 892 KKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRER 951
Query: 936 RDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDWSNTKSLW 980
R+KG+D +P+YF+++ +W +TG +YWERRK+HDWS+ LW
Sbjct: 952 RNKGQDVEPKYFEKVSKNEWKYITGPKSYWERRKKHDWSDISQLW 996
>Hs21735584 [I] KOG1737 Oxysterol-binding protein
Length = 820
Score = 215 bits (547), Expect = 3e-55
Identities = 133/385 (34%), Positives = 202/385 (51%), Gaps = 19/385 (4%)
Query: 598 QDLSP-LPINKTIKRRNDIAIPVSTPPS----LLGFLRKNVGKDLSSISMPISLNEPVSI 652
Q L P L + K R +P P S L LR N+GKDLS ++MP+ LNEP++
Sbjct: 429 QTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNT 488
Query: 653 LQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGET 712
LQ L E EYS LL KAA + ++R+ Y++AFA+S + + S KPF P+LGET
Sbjct: 489 LQRLCEELEYSELLDKAAQIPSP-LERMVYVAAFAISAYASSYYRAGS--KPFNPVLGET 545
Query: 713 YELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFEL 772
YE +RED G + SE+V H PPI A + E R++ V KFWGKS+E G +
Sbjct: 546 YECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHV 605
Query: 773 TFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSIST--STNLKSIIAFKAGGMFSGRS 830
T + W++ T + NI++G+R++E + I + + F +S +
Sbjct: 606 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNA 665
Query: 831 EDVDVSLVNEKGQKLGSLKGQWTKEV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNL 888
+++ ++ + G+ + L G+W + + + +W+ P+ + E+ Y FT F L
Sbjct: 666 HEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALEL 725
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERR----DKGEDAQP 944
NE+ + K LPPTD+R RPD R E G + EAE K +EQ QRERR + + QP
Sbjct: 726 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 785
Query: 945 QYFKQIKPMKWLPVTGENNYWERRK 969
++F++ W+ Y E RK
Sbjct: 786 RFFRKSDDDSWV---SNGTYLELRK 807
>Hs21735582 [I] KOG1737 Oxysterol-binding protein
Length = 851
Score = 215 bits (547), Expect = 3e-55
Identities = 133/385 (34%), Positives = 202/385 (51%), Gaps = 19/385 (4%)
Query: 598 QDLSP-LPINKTIKRRNDIAIPVSTPPS----LLGFLRKNVGKDLSSISMPISLNEPVSI 652
Q L P L + K R +P P S L LR N+GKDLS ++MP+ LNEP++
Sbjct: 460 QTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNT 519
Query: 653 LQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGET 712
LQ L E EYS LL KAA + ++R+ Y++AFA+S + + S KPF P+LGET
Sbjct: 520 LQRLCEELEYSELLDKAAQIPSP-LERMVYVAAFAISAYASSYYRAGS--KPFNPVLGET 576
Query: 713 YELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFEL 772
YE +RED G + SE+V H PPI A + E R++ V KFWGKS+E G +
Sbjct: 577 YECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHV 636
Query: 773 TFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSIST--STNLKSIIAFKAGGMFSGRS 830
T + W++ T + NI++G+R++E + I + + F +S +
Sbjct: 637 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNA 696
Query: 831 EDVDVSLVNEKGQKLGSLKGQWTKEV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNL 888
+++ ++ + G+ + L G+W + + + +W+ P+ + E+ Y FT F L
Sbjct: 697 HEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALEL 756
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERR----DKGEDAQP 944
NE+ + K LPPTD+R RPD R E G + EAE K +EQ QRERR + + QP
Sbjct: 757 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 816
Query: 945 QYFKQIKPMKWLPVTGENNYWERRK 969
++F++ W+ Y E RK
Sbjct: 817 RFFRKSDDDSWV---SNGTYLELRK 838
>Hs21735580 [I] KOG1737 Oxysterol-binding protein
Length = 856
Score = 215 bits (547), Expect = 3e-55
Identities = 133/385 (34%), Positives = 202/385 (51%), Gaps = 19/385 (4%)
Query: 598 QDLSP-LPINKTIKRRNDIAIPVSTPPS----LLGFLRKNVGKDLSSISMPISLNEPVSI 652
Q L P L + K R +P P S L LR N+GKDLS ++MP+ LNEP++
Sbjct: 465 QTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNT 524
Query: 653 LQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGET 712
LQ L E EYS LL KAA + ++R+ Y++AFA+S + + S KPF P+LGET
Sbjct: 525 LQRLCEELEYSELLDKAAQIPSP-LERMVYVAAFAISAYASSYYRAGS--KPFNPVLGET 581
Query: 713 YELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFEL 772
YE +RED G + SE+V H PPI A + E R++ V KFWGKS+E G +
Sbjct: 582 YECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHV 641
Query: 773 TFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSIST--STNLKSIIAFKAGGMFSGRS 830
T + W++ T + NI++G+R++E + I + + F +S +
Sbjct: 642 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNA 701
Query: 831 EDVDVSLVNEKGQKLGSLKGQWTKEV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNL 888
+++ ++ + G+ + L G+W + + + +W+ P+ + E+ Y FT F L
Sbjct: 702 HEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALEL 761
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERR----DKGEDAQP 944
NE+ + K LPPTD+R RPD R E G + EAE K +EQ QRERR + + QP
Sbjct: 762 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 821
Query: 945 QYFKQIKPMKWLPVTGENNYWERRK 969
++F++ W+ Y E RK
Sbjct: 822 RFFRKSDDDSWV---SNGTYLELRK 843
>Hs14149704 [I] KOG1737 Oxysterol-binding protein
Length = 887
Score = 215 bits (547), Expect = 3e-55
Identities = 133/385 (34%), Positives = 202/385 (51%), Gaps = 19/385 (4%)
Query: 598 QDLSP-LPINKTIKRRNDIAIPVSTPPS----LLGFLRKNVGKDLSSISMPISLNEPVSI 652
Q L P L + K R +P P S L LR N+GKDLS ++MP+ LNEP++
Sbjct: 496 QTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNT 555
Query: 653 LQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGET 712
LQ L E EYS LL KAA + ++R+ Y++AFA+S + + S KPF P+LGET
Sbjct: 556 LQRLCEELEYSELLDKAAQIPSP-LERMVYVAAFAISAYASSYYRAGS--KPFNPVLGET 612
Query: 713 YELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFEL 772
YE +RED G + SE+V H PPI A + E R++ V KFWGKS+E G +
Sbjct: 613 YECIREDKGFQFFSEQVSHHPPISACHAESRNFVFWQDVRWKNKFWGKSMEIVPIGTTHV 672
Query: 773 TFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSIST--STNLKSIIAFKAGGMFSGRS 830
T + W++ T + NI++G+R++E + I + + F +S +
Sbjct: 673 TLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTNA 732
Query: 831 EDVDVSLVNEKGQKLGSLKGQWTKEV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNL 888
+++ ++ + G+ + L G+W + + + +W+ P+ + E+ Y FT F L
Sbjct: 733 HEIEGTVFDRSGKAVHRLFGKWHESIYCGGGSSSACVWRANPMPKGYEQYYSFTQFALEL 792
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERR----DKGEDAQP 944
NE+ + K LPPTD+R RPD R E G + EAE K +EQ QRERR + + QP
Sbjct: 793 NEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQRERRRVLEENHVEHQP 852
Query: 945 QYFKQIKPMKWLPVTGENNYWERRK 969
++F++ W+ Y E RK
Sbjct: 853 RFFRKSDDDSWV---SNGTYLELRK 874
>Hs19718746 [T] KOG2209 Oxysterol-binding protein
Length = 437
Score = 213 bits (541), Expect = 2e-54
Identities = 140/409 (34%), Positives = 208/409 (50%), Gaps = 69/409 (16%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
S+ LRK +G +LS I+MP+ NEP+S LQ L+E E+++L+ KA+++ D V+R++ +
Sbjct: 35 SIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDP-VERMQCV 93
Query: 684 SAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTE-- 741
+AFA+S ++ ++T KPF PLLGETYELVR+D+G RL+SE+V H PPI AF+ E
Sbjct: 94 AAFAVSAVASQWERTG---KPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGL 150
Query: 742 HRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME 801
+ D+ ++ P KFWGKS+E +G L + Y W+ PT + NII G+ ++E
Sbjct: 151 NNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIE 210
Query: 802 P-SNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT------- 853
N I+ T K ++ FK G+F V+ + ++ +KL +L G+WT
Sbjct: 211 QYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVD 270
Query: 854 ------------KEVRDLDNGQQ--------------------------IWKCGPLVENS 875
K + N +Q +W+ P NS
Sbjct: 271 PATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNS 330
Query: 876 EKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR-- 933
+ Y FT F LNE+ + + +P TD RLRPDIR ENG I +A + K LE+KQR
Sbjct: 331 AQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAA 390
Query: 934 --ERRDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDWSNTKSLW 980
R ED + ++F Q G N Y DW + S W
Sbjct: 391 RKNRSKSEEDWKTRWFHQ----------GPNPY---NGAQDWIYSGSYW 426
>Hs19718741 [T] KOG2209 Oxysterol-binding protein
Length = 950
Score = 213 bits (541), Expect = 2e-54
Identities = 140/409 (34%), Positives = 208/409 (50%), Gaps = 69/409 (16%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
S+ LRK +G +LS I+MP+ NEP+S LQ L+E E+++L+ KA+++ D V+R++ +
Sbjct: 548 SIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDP-VERMQCV 606
Query: 684 SAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTE-- 741
+AFA+S ++ ++T KPF PLLGETYELVR+D+G RL+SE+V H PPI AF+ E
Sbjct: 607 AAFAVSAVASQWERTG---KPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGL 663
Query: 742 HRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME 801
+ D+ ++ P KFWGKS+E +G L + Y W+ PT + NII G+ ++E
Sbjct: 664 NNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIE 723
Query: 802 P-SNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT------- 853
N I+ T K ++ FK G+F V+ + ++ +KL +L G+WT
Sbjct: 724 QYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVD 783
Query: 854 ------------KEVRDLDNGQQ--------------------------IWKCGPLVENS 875
K + N +Q +W+ P NS
Sbjct: 784 PATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNS 843
Query: 876 EKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR-- 933
+ Y FT F LNE+ + + +P TD RLRPDIR ENG I +A + K LE+KQR
Sbjct: 844 AQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAA 903
Query: 934 --ERRDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDWSNTKSLW 980
R ED + ++F Q G N Y DW + S W
Sbjct: 904 RKNRSKSEEDWKTRWFHQ----------GPNPY---NGAQDWIYSGSYW 939
>Hs22035612 [I] KOG1737 Oxysterol-binding protein
Length = 938
Score = 209 bits (533), Expect = 1e-53
Identities = 134/378 (35%), Positives = 203/378 (53%), Gaps = 22/378 (5%)
Query: 618 PVSTPPSLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEV 677
P ++ +L LR N+GKDLS +SMP+ LNEP++ LQ L E EYS LL KA+ DD
Sbjct: 568 PDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET-DDPY 626
Query: 678 QRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIF 736
+R+ ++AFA+S Y S + R+ KPF P+LGETYE +RED G R SE+V H PPI
Sbjct: 627 ERMVLVAAFAVSGYCSTY---FRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPIS 683
Query: 737 AFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAG 796
A + E +++ + KFWGKS+E G + Y W++ T + NI++G
Sbjct: 684 ACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSG 743
Query: 797 ERYMEPSNQFSISTSTNLKSI--IAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTK 854
R++E + +I + + I + F ++ +V +++++G+ + L G+W +
Sbjct: 744 RRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHE 803
Query: 855 EV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRL 912
+ + + IW+ G + N E YGFT F LNE+ KD LPPTD+R RPD R
Sbjct: 804 GLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 863
Query: 913 YENGIITEAEQMKLSLEQKQRERRDKGEDAQ----PQYFKQI----KPMKWLPVTGENNY 964
E G + A K +E+ QR RR E+ P++FK++ + W+ + Y
Sbjct: 864 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWV---SNDTY 920
Query: 965 WERRKRHDWSNTKS--LW 980
WE RK +S S LW
Sbjct: 921 WELRKDPGFSKVDSPVLW 938
>Hs14210532 [I] KOG1737 Oxysterol-binding protein
Length = 934
Score = 209 bits (533), Expect = 1e-53
Identities = 134/378 (35%), Positives = 203/378 (53%), Gaps = 22/378 (5%)
Query: 618 PVSTPPSLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEV 677
P ++ +L LR N+GKDLS +SMP+ LNEP++ LQ L E EYS LL KA+ DD
Sbjct: 564 PDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASET-DDPY 622
Query: 678 QRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIF 736
+R+ ++AFA+S Y S + R+ KPF P+LGETYE +RED G R SE+V H PPI
Sbjct: 623 ERMVLVAAFAVSGYCSTY---FRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPIS 679
Query: 737 AFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAG 796
A + E +++ + KFWGKS+E G + Y W++ T + NI++G
Sbjct: 680 ACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSG 739
Query: 797 ERYMEPSNQFSISTSTNLKSI--IAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTK 854
R++E + +I + + I + F ++ +V +++++G+ + L G+W +
Sbjct: 740 RRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHE 799
Query: 855 EV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRL 912
+ + + IW+ G + N E YGFT F LNE+ KD LPPTD+R RPD R
Sbjct: 800 GLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRF 859
Query: 913 YENGIITEAEQMKLSLEQKQRERRDKGEDAQ----PQYFKQI----KPMKWLPVTGENNY 964
E G + A K +E+ QR RR E+ P++FK++ + W+ + Y
Sbjct: 860 LEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWV---SNDTY 916
Query: 965 WERRKRHDWSNTKS--LW 980
WE RK +S S LW
Sbjct: 917 WELRKDPGFSKVDSPVLW 934
>HsM19923507 [I] KOG1737 Oxysterol-binding protein
Length = 842
Score = 208 bits (529), Expect = 4e-53
Identities = 133/375 (35%), Positives = 199/375 (52%), Gaps = 22/375 (5%)
Query: 617 IPVSTPP----SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATM 672
+P ++ P SL LR N+GKDLS +SMP+ LNEP++ LQ L E EYS LL +A+ +
Sbjct: 467 LPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRI 526
Query: 673 EDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCH 731
D +R+ YI+AFA+S Y S + R+ KPF P+LGETYE R D G R +SE+V H
Sbjct: 527 ADP-CERMVYIAAFAVSAYSSTYH---RAGCKPFNPVLGETYECERPDRGFRFISEQVSH 582
Query: 732 KPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLK 791
PPI A + E ++ + KFWGKS+E G ++ + W++ T +
Sbjct: 583 HPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIH 642
Query: 792 NIIAGERYMEPSNQFSI--STSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLK 849
N+++G+R++E + I + ++ I F +S +V ++++ G+ L L
Sbjct: 643 NVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVLHRLF 702
Query: 850 GQWTKEV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLR 907
G+W + + GQ IWK + + E+ +GFT F LNE+T K LP TD+RLR
Sbjct: 703 GKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLR 762
Query: 908 PDIRLYENGIITEAEQMKLSLEQKQRERRDKGED----AQPQYFKQ---IKPMKWLPVTG 960
PD R E G I AE K +EQ QR+RR E+ Q ++F++ +W
Sbjct: 763 PDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEWW--VT 820
Query: 961 ENNYWERRKRHDWSN 975
N YW R + N
Sbjct: 821 NNTYWRLRAEPGYGN 835
>Hs22035614 [I] KOG1737 Oxysterol-binding protein
Length = 842
Score = 208 bits (529), Expect = 4e-53
Identities = 133/375 (35%), Positives = 199/375 (52%), Gaps = 22/375 (5%)
Query: 617 IPVSTPP----SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATM 672
+P ++ P SL LR N+GKDLS +SMP+ LNEP++ LQ L E EYS LL +A+ +
Sbjct: 467 LPAASGPGADVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRI 526
Query: 673 EDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCH 731
D +R+ YI+AFA+S Y S + R+ KPF P+LGETYE R D G R +SE+V H
Sbjct: 527 ADP-CERMVYIAAFAVSAYSSTYH---RAGCKPFNPVLGETYECERPDRGFRFISEQVSH 582
Query: 732 KPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLK 791
PPI A + E ++ + KFWGKS+E G ++ + W++ T +
Sbjct: 583 HPPISACHAESENFAFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIH 642
Query: 792 NIIAGERYMEPSNQFSI--STSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLK 849
N+++G+R++E + I + ++ I F +S +V ++++ G+ L L
Sbjct: 643 NVLSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNVHEVQGAVLSRSGRVLHRLF 702
Query: 850 GQWTKEV--RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLR 907
G+W + + GQ IWK + + E+ +GFT F LNE+T K LP TD+RLR
Sbjct: 703 GKWHEGLYRGPTPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLR 762
Query: 908 PDIRLYENGIITEAEQMKLSLEQKQRERRDKGED----AQPQYFKQ---IKPMKWLPVTG 960
PD R E G I AE K +EQ QR+RR E+ Q ++F++ +W
Sbjct: 763 PDQRYLEEGNIQAAEAQKRRIEQLQRDRRKVMEENNIVHQARFFRRQTDSSGKEWW--VT 820
Query: 961 ENNYWERRKRHDWSN 975
N YW R + N
Sbjct: 821 NNTYWRLRAEPGYGN 835
>Hs7662298 [T] KOG2209 Oxysterol-binding protein
Length = 468
Score = 200 bits (509), Expect = 8e-51
Identities = 137/416 (32%), Positives = 213/416 (50%), Gaps = 64/416 (15%)
Query: 580 ELMTSTDRKTIETATSRSQDLSPLPINKTIKRRNDIAIPVSTPP--SLLGFLRKNVGKDL 637
+L TS + + +T SQ+ N K R + P+ + S+ L+K VG +L
Sbjct: 23 DLDTSKNNRIGKTGERPSQE------NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLEL 76
Query: 638 SSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQK 697
S I+MPI+ NEP+S LQ ++E E+ +L+ +A+ + ++R++ ++AFA+S ++ ++
Sbjct: 77 SKITMPIAFNEPLSFLQRITEYMEHVYLIHRASC-QPQPLERMQSVAAFAVSAVASQWER 135
Query: 698 TRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTE--HRDWKCSYTVTPVQ 755
T KPF PLLGETYEL+RED+G R +SE+V H PPI AF++E + D+ ++ P
Sbjct: 136 TG---KPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKL 192
Query: 756 KFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSI-STSTNL 814
KFWGKS+E G L + Y W+ PT + N+I G+ ++E I + T
Sbjct: 193 KFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGH 252
Query: 815 KSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT--------------------- 853
K ++ FK G+F V+ + ++ +KL + G+WT
Sbjct: 253 KCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRG 312
Query: 854 ----KEVRDLDNGQQ-----------------------IWKCGPLVENSEKKYGFTVFTS 886
K D D+G+ +W+ NS + Y FT FT
Sbjct: 313 DHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINTRPPNSAQMYNFTSFTV 372
Query: 887 NLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRE-RRDKGED 941
+LNE+ + LPPTD RLRPDIR ENG + A Q K LE+KQRE RR++ ++
Sbjct: 373 SLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKE 428
>Hs21450853 [T] KOG2209 Oxysterol-binding protein
Length = 480
Score = 200 bits (509), Expect = 8e-51
Identities = 137/416 (32%), Positives = 213/416 (50%), Gaps = 64/416 (15%)
Query: 580 ELMTSTDRKTIETATSRSQDLSPLPINKTIKRRNDIAIPVSTPP--SLLGFLRKNVGKDL 637
+L TS + + +T SQ+ N K R + P+ + S+ L+K VG +L
Sbjct: 35 DLDTSKNNRIGKTGERPSQE------NGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLEL 88
Query: 638 SSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSIHRQK 697
S I+MPI+ NEP+S LQ ++E E+ +L+ +A+ + ++R++ ++AFA+S ++ ++
Sbjct: 89 SKITMPIAFNEPLSFLQRITEYMEHVYLIHRASC-QPQPLERMQSVAAFAVSAVASQWER 147
Query: 698 TRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTE--HRDWKCSYTVTPVQ 755
T KPF PLLGETYEL+RED+G R +SE+V H PPI AF++E + D+ ++ P
Sbjct: 148 TG---KPFNPLLGETYELIREDLGFRFISEQVSHHPPISAFHSEGLNHDFLFHGSIYPKL 204
Query: 756 KFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSI-STSTNL 814
KFWGKS+E G L + Y W+ PT + N+I G+ ++E I + T
Sbjct: 205 KFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVIIGKLWIEQYGTVEILNHRTGH 264
Query: 815 KSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT--------------------- 853
K ++ FK G+F V+ + ++ +KL + G+WT
Sbjct: 265 KCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECLWGIDPVSYESFKKQERRG 324
Query: 854 ----KEVRDLDNGQQ-----------------------IWKCGPLVENSEKKYGFTVFTS 886
K D D+G+ +W+ NS + Y FT FT
Sbjct: 325 DHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPGSKLLWRINTRPPNSAQMYNFTSFTV 384
Query: 887 NLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRE-RRDKGED 941
+LNE+ + LPPTD RLRPDIR ENG + A Q K LE+KQRE RR++ ++
Sbjct: 385 SLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARRERAKE 440
>At1g13170 [I] KOG1737 Oxysterol-binding protein
Length = 816
Score = 191 bits (484), Expect = 6e-48
Identities = 135/406 (33%), Positives = 206/406 (50%), Gaps = 27/406 (6%)
Query: 594 TSRSQDLSPLPINKTIKRRNDIAIPVST--PPSLLGFLRKNVGKDLSSISMPISLNEPVS 651
+ R Q + +P ++RR+++ P P L +++N+GKDLS + +P+ NEP+S
Sbjct: 401 SDRLQIPARIPQYPYVRRRDNLPEPKEKEKPVGLWSIIKENIGKDLSGVCLPVYFNEPLS 460
Query: 652 ILQVLSEAFEYSWLLSKAATM--EDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPL 708
LQ E EYS+L+ +A + +E+ R+ I+AFA+S Y S ++ KPF PL
Sbjct: 461 SLQKCFEDLEYSYLIDRALEWGKQGNELMRILNIAAFAVSGYASTEGRQC----KPFNPL 516
Query: 709 LGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEG 768
LGETYE D G+R SEKV H P I A + E + W KFWG+SI+ G
Sbjct: 517 LGETYEADYPDKGLRFFSEKVSHHPMIVACHCEGQGWNFWGDSNIKGKFWGRSIQLDPVG 576
Query: 769 VFELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSG 828
V L F++ + Y+WS+ T + NII G+ Y + I +N + FK +
Sbjct: 577 VLTLKFDDGEI-YQWSKVTTSIYNIILGKLYCDHYGTMRIKGGSNYSCRLKFKEQSVIDR 635
Query: 829 RSEDVDVSLV-NEKGQKLGSLKGQWTKEVRDLDNGQQIWKCG--PLVEN----------S 875
V + N G+K+ L G+W + + + G P+ E +
Sbjct: 636 NPRQVHGFVQDNRTGEKVAILIGKWDEAMYYVLGDPTTKPKGYDPMTEAVLLWERDKSPT 695
Query: 876 EKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRE- 934
+ +Y + F +LNEIT D LPPTDSRLRPD R ENG A KL LEQ QR+
Sbjct: 696 KTRYNLSPFAISLNEITPGMIDKLPPTDSRLRPDQRHLENGEYESANAEKLRLEQLQRQA 755
Query: 935 RRDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDWSNTKSLW 980
RR + + +P++F++ + + + G YWE R++ DW ++
Sbjct: 756 RRLQEKGWKPRWFEKDEEGNYRYLGG---YWEAREKKDWDRITDIF 798
>At2g31020 [I] KOG1737 Oxysterol-binding protein
Length = 760
Score = 189 bits (481), Expect = 1e-47
Identities = 126/385 (32%), Positives = 190/385 (48%), Gaps = 21/385 (5%)
Query: 609 IKRRNDIAIPVSTPPS--LLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLL 666
+KRR + PV S L ++ N+GKDL+ + +P+ NEP+S LQ E EYS+LL
Sbjct: 376 VKRRKKLPDPVEKEKSVSLWSMIKDNIGKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLL 435
Query: 667 SKAATM--EDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIR 723
+A+ + + R+ ++AFA+S Y S + + KPF P+LGETYE D G+R
Sbjct: 436 DQASEWGKRGNNLMRILNVAAFAVSGYASTEGR----ICKPFNPMLGETYEADYPDKGLR 491
Query: 724 LVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRW 783
SEKV H P I A + + WK KFWG+SI+ G+ L F++ + +W
Sbjct: 492 FFSEKVSHHPMIVACHCDGTGWKFWGDSNLKSKFWGRSIQLDPIGLLTLQFDDGEI-VQW 550
Query: 784 SQPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQ 843
S+ T + N+I G+ Y + I + + FK M V + ++ G+
Sbjct: 551 SKVTTSIYNLILGKLYCDHYGTMKIEGNGEYSCKLKFKEQSMIDRNPHQVQGIVEDKNGK 610
Query: 844 KLGSLKGQWTKEVR-------DLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEK 896
+ L G+W + + ++ +WK EN K Y T F LNE+T K
Sbjct: 611 TVARLFGKWDESIHYVMVDQGKVNESHLLWKRNKQPENPTK-YNLTRFGITLNELTPGLK 669
Query: 897 DHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERRDKGEDA-QPQYFKQIKPMKW 955
+ LPPTDSRLRPD R E G KL LEQ+QR+ R+ E +P++F++ K +
Sbjct: 670 EKLPPTDSRLRPDQRYLEKGEYEMGNAEKLRLEQRQRQAREMQERGWKPKWFRKEKGSET 729
Query: 956 LPVTGENNYWERRKRHDWSNTKSLW 980
G YWE R W + ++
Sbjct: 730 YRYIG--GYWEARDSGSWDDCPDIF 752
>At2g31030 [I] KOG1737 Oxysterol-binding protein
Length = 489
Score = 189 bits (480), Expect = 2e-47
Identities = 126/384 (32%), Positives = 194/384 (49%), Gaps = 19/384 (4%)
Query: 609 IKRRNDIAIPVSTPPS--LLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLL 666
+ RRN + PV S L ++ N+GKDL+ + +P+ NEP+S LQ E EYS+LL
Sbjct: 109 VNRRNKLPDPVEKEKSVSLWSMIKDNIGKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLL 168
Query: 667 SKAATM--EDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRL 724
+A+ + + R+ ++AFA+S + + + + KPF P+LGETYE D G+R
Sbjct: 169 DQASEWGKRGNNLMRILNVAAFAVSGYASTKGR---ICKPFNPMLGETYEADYPDKGLRF 225
Query: 725 VSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWS 784
SEKV H P I A + + WK KFWG+SI+ G+ L F++ + +WS
Sbjct: 226 FSEKVSHHPMIVACHCDGTGWKFWGDSNLKSKFWGRSIQLDPIGLLTLQFDDGEI-VQWS 284
Query: 785 QPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQK 844
+ T + N+I G+ Y + I + + FK M V + ++ G+
Sbjct: 285 KVTTSIYNLILGKLYCDHYGTMLIEGNGEYSCKLKFKKQSMMDRNPHQVQGIVEDKNGKT 344
Query: 845 LGSLKGQWTKEVRDL--DNGQQ-----IWKCGPLVENSEKKYGFTVFTSNLNEITETEKD 897
+ L G+W + + + + G++ +WK +EN K Y T F LNE+T K+
Sbjct: 345 VAKLFGKWDESMYYVMVNQGKESESHLLWKRNKPLENPTK-YNLTRFGITLNELTPDLKE 403
Query: 898 HLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERRDKGEDA-QPQYFKQIKPMKWL 956
LPPTDSRLRPD R E G + KL LEQ+QR+ R+K E +P +F + K +
Sbjct: 404 MLPPTDSRLRPDQRYLEKGEFEMGNREKLRLEQRQRQAREKQERGWKPTWFSKEKGSETY 463
Query: 957 PVTGENNYWERRKRHDWSNTKSLW 980
G YWE R W + ++
Sbjct: 464 RYIG--GYWEARDSGRWDDCPDIF 485
>7301240 [I] KOG1737 Oxysterol-binding protein
Length = 784
Score = 187 bits (475), Expect = 7e-47
Identities = 132/409 (32%), Positives = 204/409 (49%), Gaps = 47/409 (11%)
Query: 610 KRRNDIAIPVSTPPSLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKA 669
KRR+ + + P SL G ++ +GKDLS I MPI+ NEP+S+LQ L E +EY+ +L A
Sbjct: 385 KRRDRVPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYA 444
Query: 670 ATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVR-EDMGIRLVSEK 728
AT + DE ++L YI+AF +S + T KPF PLLGETYE R +D G R ++E+
Sbjct: 445 ATCQ-DECEQLAYIAAFT---VSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQ 500
Query: 729 VCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTI 788
V H PP+ A + E ++W C + KF GK ++ G + F N +Y W + T
Sbjct: 501 VSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTT 560
Query: 789 VLKNIIAGERYMEPSNQFSI---STSTNLKSIIAFKAGGMFS-GRSEDVDVSLVNEKGQK 844
+ NII G+ +++ + I + K I+ F FS V ++N+ +
Sbjct: 561 TVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEV 620
Query: 845 LGSLKGQWTKEVR----------------DLDNGQQIWKCGPLVENSEKKYGFTVFTSNL 888
++G W ++ + W+ P +S+K Y FT L
Sbjct: 621 KWVVRGTWDMKIEIAPVLKTSGSVSSPTYTTGEFKLAWRRRPAPPDSDKFYNFTTLACQL 680
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR-ERRDKGEDA----- 942
NE E++ + PTDSRLRPD RL E G E+ + KL LE+KQR ERR + +A
Sbjct: 681 NE----EEEGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRRENEAEEAAA 736
Query: 943 --------QPQYFKQIK---PMKWLPVTGENNYWERRKRHDWSNTKSLW 980
+P +FK+ K +++ V +N YWE + ++ ++
Sbjct: 737 EGRPYPAYEPMWFKREKEEGSEEYVHVF-KNTYWEAKAAQNFEGCPDIY 784
>At4g08180 [I] KOG1737 Oxysterol-binding protein
Length = 830
Score = 187 bits (474), Expect = 9e-47
Identities = 129/401 (32%), Positives = 191/401 (47%), Gaps = 44/401 (10%)
Query: 609 IKRRNDIAIPVSTPPS--LLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLL 666
+KRR ++ PV S L ++ N+GKDL+ + +P+ NEP+S LQ E EYS+LL
Sbjct: 420 VKRRKNLPDPVEKEKSVSLWSMIKDNIGKDLTKVCLPVYFNEPLSSLQKCFEDLEYSYLL 479
Query: 667 SKAATM--EDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIR 723
+A + + R+ ++AFA+S Y S + + KPF PLLGETYE D G+R
Sbjct: 480 DRAFEYGKRGNSLMRILNVAAFAVSGYASTEGR----ICKPFNPLLGETYEADYPDKGLR 535
Query: 724 LVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRW 783
SEKV H P + A + + WK KFWG+SI+ GV L F++ + +W
Sbjct: 536 FFSEKVSHHPMVVACHCDGTGWKFWGDSNLRSKFWGRSIQLDPVGVLTLQFDDGEI-LQW 594
Query: 784 SQPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQ 843
S+ T + N+I G+ Y + I S + FK + V + N+ G+
Sbjct: 595 SKVTTSIYNLILGKLYCDHYGTMRIEGSAEYSCKLKFKEQSIIDRNPHQVHGIVQNKSGK 654
Query: 844 KLGSLKGQWTKEVR--------------DLDNGQQIWKCGPLVENSEKKYGFTVFTSNLN 889
+ ++ G+W + + D+ Q +WK N+ K Y T F LN
Sbjct: 655 TVATMFGKWDESIHFVTGDCSGKGKLSEDMSGAQLLWKRSKPPGNATK-YNLTRFAITLN 713
Query: 890 EITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRE--------------- 934
E+T K+ LPPTDSRLRPD R ENG A KL LEQ+QR+
Sbjct: 714 ELTPGLKERLPPTDSRLRPDQRYLENGEFEMANTEKLRLEQRQRQNELELTCYKLGCVMR 773
Query: 935 --RRDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDW 973
R+ + +P++F + K + G YWE R+ W
Sbjct: 774 QARKMQERGWKPRWFMKEKGSESYRYKG--GYWEAREDGSW 812
>SPAC23H4.01c [I] KOG1737 Oxysterol-binding protein
Length = 749
Score = 182 bits (462), Expect = 2e-45
Identities = 161/617 (26%), Positives = 264/617 (42%), Gaps = 101/617 (16%)
Query: 264 GYLLKKKRKKLQGFTKRFFKLDIKFGILSYYLNSKSPVCRGEIVVPLSSISANKQTKLII 323
G LLKK+RKK QG+ +R+F L++ G +SYY N S V RG+I + ++ IS +T I
Sbjct: 154 GTLLKKRRKKGQGYARRYFTLNMVEGTISYYANENSSVMRGKIPLSIAVISVAAETHEIN 213
Query: 324 IDSGMEIWVMKARDEKDWELWISMIESCFKQDAPTTSQDHESHNVVIPPDNDTTAFFRNL 383
+DSG+E+W ++A +DW W + +E +++ ++ + ++ + + L
Sbjct: 214 VDSGVELWNLRAHTHQDWLRWCNALEK---------AKNSQTSSKLVVDERTQESSSNQL 264
Query: 384 TSLRKRIEEC----------KYQSLSYSNYTPNAIVSPIQG-----PPTXXXXXXXXXXX 428
S+ R+ EC + +S S N++ I + G T
Sbjct: 265 VSIYSRLRECLDIAQLYRTSRIKSASSHNFSVPEIRIQLPGDAKENKETRTSVEITAAEN 324
Query: 429 XXXXXXXXXXXRQRNGSFV--------------EQATSGHDTSILSNNPNEPQHHDLYRK 474
RQ GS + E+ +S +S + N QH +
Sbjct: 325 AQAAVTLRKVTRQL-GSLLHELECFIQHHEYTKERTAQSSPSSRMSMDSNFEQH---WYD 380
Query: 475 LADLEKIAKQLDIDGKMLATKWVPRSPTASIFSDDEYFDANEE--PIITMLNDDVAFETD 532
D E QL+ + A + +S+ +++ D ++ PI+ ++ + + D
Sbjct: 381 AEDYESTTSQLNHYSESGA--HAADATKSSVAHNEKVEDISDSDIPIMKTSSNSTSLDAD 438
Query: 533 IRPIYSSYNDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPTSNE-----------L 581
SS +D ++ E L
Sbjct: 439 RDSDTSSISDTSSNSSAPHEQLNATSLASTVDESSRSPPLPEVESNKENDIKRKQPFHDL 498
Query: 582 MTSTDRKTIETATSRSQDLSPLP-INKTIKRRNDIAIPVSTPP------SLLGFLRKNVG 634
M S+ A ++S + P ++K I I+IP P SL VG
Sbjct: 499 MDSSSPDDSSFANAKSDEEVQKPSVSKNIADGAVISIPKPLTPKPSDSNSLYPLPHSKVG 558
Query: 635 --KDLSSISMPISLNEPVSILQVL---------------------------SEAFEYSWL 665
K++ +I++P P SIL +L +E EYS +
Sbjct: 559 RRKNIPAITVP-----PPSILSILRKNIGKDISSIPAPVVSNEPCNLLQRCAEDLEYSNM 613
Query: 666 LSKAATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLV 725
L KA +DD ++ Y++AFA+S S R K RS+RK F+PLLGET+ELVRED R +
Sbjct: 614 LDKANECDDD--IKIFYVAAFAVSNFSNMRHKERSVRKVFSPLLGETFELVREDRNYRFL 671
Query: 726 SEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQ 785
+EKVCH+P I A + E R+W +++ P+QKFWGKS+E G + ++ + +
Sbjct: 672 AEKVCHRPLIIACHAESRNWIWNHSPKPIQKFWGKSVELNTLGPVTIKL-ACGTEFSFMK 730
Query: 786 PTIVLKNIIAGERYMEP 802
P LKN+ GE+Y+EP
Sbjct: 731 PACFLKNVAIGEKYVEP 747
>At4g12460 [I] KOG1737 Oxysterol-binding protein
Length = 694
Score = 181 bits (458), Expect = 6e-45
Identities = 123/384 (32%), Positives = 187/384 (48%), Gaps = 21/384 (5%)
Query: 610 KRRNDIAIPVSTPP--SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLS 667
KRR + P SL ++ NVGKDL+ + +P+ NEP+S LQ E EYS+LL
Sbjct: 308 KRRTKLPDPAEKERGVSLWSMIKDNVGKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLLD 367
Query: 668 KAATM--EDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRL 724
+A + R ++AFA+S Y S + KPF PLLGETYE + GIR
Sbjct: 368 QAYEYGKSGKSLLRALNVAAFAVSGYASTEGRHC----KPFNPLLGETYEADFPEKGIRF 423
Query: 725 VSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWS 784
SEKV H P + A + E + WK KFWG+SI+ G+ L F++ + ++WS
Sbjct: 424 FSEKVSHHPTVIACHCEGKGWKFWGDTNLRSKFWGRSIQLEPVGILTLEFDDGEI-FQWS 482
Query: 785 QPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQK 844
+ T + NI+ G+ Y + I + ++ FK + V+ + + G+K
Sbjct: 483 KVTTTIYNILLGKLYCDHHGIMKIRGNRQYSCMLKFKEQSILDRNPHQVNGFVEDVTGKK 542
Query: 845 LGSLKGQWTKEVR-------DLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKD 897
++ G+W + + + +WK N +Y FT F LNE+ ++
Sbjct: 543 AATVFGKWNDSLYYVAGDGINKASASLLWKATKAPPN-VTRYNFTSFAMTLNELIPGLEE 601
Query: 898 HLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERRDKGEDA-QPQYFKQIKPMKWL 956
LPPTDSRLRPD R ENG +A + K LE++QR R E +P++F+ +
Sbjct: 602 KLPPTDSRLRPDQRHLENGEYEKANEEKQRLERRQRMSRQIQESGWRPRWFEPQGESESY 661
Query: 957 PVTGENNYWERRKRHDWSNTKSLW 980
TG YWE R W + +++
Sbjct: 662 KYTG--GYWEARDVKSWDDCPNIF 683
>CE23653 [T] KOG2209 Oxysterol-binding protein
Length = 471
Score = 178 bits (451), Expect = 4e-44
Identities = 124/421 (29%), Positives = 190/421 (44%), Gaps = 76/421 (18%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDE------- 676
S+ +R N+GKD S ++P+ +NEP+S LQ LSE +Y++LL KAA DD
Sbjct: 44 SIWDIIRPNLGKDFSRFTVPVFMNEPLSFLQRLSENVQYNYLLEKAAKCSDDMERIEFYE 103
Query: 677 ---------------------------VQRLKYISAFALSYMSIHRQKTRSLRKPFTPLL 709
+ Y++AFAL+ +S + ++ L KPF PLL
Sbjct: 104 FRFFFNWKKLKHQMKLSNSAHKTGFTFANSINYVAAFALATVSANHKR---LSKPFNPLL 160
Query: 710 GETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGV 769
ET+EL R G+R ++E+V H PPI A Y E ++ TV P FW +
Sbjct: 161 LETFELERN--GVRFLAEQVSHHPPISAVYAESDEFTVEGTVEPTLGFWMTKLLANPHAH 218
Query: 770 FELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGR 829
+LTF Y WS P + N+I G+ YM ++ I +S ++ +F G ++ +
Sbjct: 219 LKLTFKKTGETYSWSAPKCAIYNVIMGKMYMNFTSHMKIESSGTYDAVFSFDNKGYYNHK 278
Query: 830 SEDVDVS-LVNEKGQKLGSLKGQWTKEVRDLDN--------------------------- 861
DV V + E K+ +L G WT + DN
Sbjct: 279 GGDVHVEGHIFEGKNKIKALYGNWTLFLASCDNEDFKHHRKEYLRMFNETVSEKDQGPVV 338
Query: 862 --GQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIIT 919
+ +W + + + ++ FT FT +LNE+ D + PTDSR R D++ E+G
Sbjct: 339 PGSKILWVSNQIPKLFDDQFHFTNFTLSLNEMYPGMSDTVAPTDSRRRKDMKALEDGKND 398
Query: 920 EAEQMKLSLEQKQRERRDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDWSNTKSL 979
EAE+ K E++QRERR P +F + W + YW+R D+SN L
Sbjct: 399 EAEEFKHKYEEEQRERRTTKTGDVPMWFAKNDEGHW---AYKGGYWDR----DYSNCLEL 451
Query: 980 W 980
+
Sbjct: 452 F 452
>SPBC2F12.05c_2 [I] KOG1737 Oxysterol-binding protein
Length = 499
Score = 177 bits (450), Expect = 5e-44
Identities = 124/385 (32%), Positives = 189/385 (48%), Gaps = 39/385 (10%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
SL G L+ +GKD++ +++P+S NEP S+LQ ++E EY+ LL +A+ +D QR+ Y+
Sbjct: 126 SLWGILKGMIGKDMTKMTLPVSFNEPTSLLQRVAEDMEYTELLDQASHNKDP-YQRILYV 184
Query: 684 SAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHR 743
+AFA S + + KPF PLLGETYE G R + E+V H PP+ A Y+E
Sbjct: 185 AAFAASE---YASTLNRVAKPFNPLLGETYEFCHPQRGFRFIVEQVSHHPPVGAAYSESA 241
Query: 744 DWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAK---YRWSQPTIVLKNIIAGERYM 800
+WK + KF+GKS + + G + L + + Y W + T + II G +
Sbjct: 242 NWKYYGESSVKSKFYGKSFDISPLGTWFLELRHPSGEVELYTWKKVTSSVVGIILGSPSV 301
Query: 801 EPSNQFSI-STSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKEV-RD 858
+ Q I + S+ + ++ FK G + +V S+ + + G W ++
Sbjct: 302 DNYGQMHIVNHSSGINCVLDFKPRGWRGTNAHEVKGSVQSTDDTPKWMVNGHWNDKIFGQ 361
Query: 859 LDNGQQI--WKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENG 916
NG +I W+ E + + T F +LN +T K LPPTD+RLRPD R ENG
Sbjct: 362 QPNGNKILLWQNH---ERPPRPFNLTPFAISLNALTPQLKPWLPPTDTRLRPDQRAMENG 418
Query: 917 IITEAEQMKLSLEQKQRERRDKGEDAQ-----PQYFKQIKPMKWLPVTGE------NNYW 965
A K LE+KQR++R E + P++F K PVTGE N YW
Sbjct: 419 QYDLAASEKNRLEEKQRKKRRMREQGEMPPWSPRWFSAAKH----PVTGEDYWQFNNEYW 474
Query: 966 ERR----------KRHDWSNTKSLW 980
+ R K +W N ++
Sbjct: 475 KIREEAGEAHLAGKEFEWPNVDDIF 499
>YAR044w [I] KOG1737 Oxysterol-binding protein
Length = 859
Score = 172 bits (437), Expect = 2e-42
Identities = 129/414 (31%), Positives = 195/414 (46%), Gaps = 55/414 (13%)
Query: 612 RNDIAIPVSTPPS--LLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKA 669
R +A+ P L L+ VG+DL+ +++P+S NEP S+LQ +SE EYS +L +A
Sbjct: 456 RTKLALDEDNRPKIGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQA 515
Query: 670 ATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKV 729
AT ED + R+ Y++AF S ++ T + KPF PLLGET+E R D R +E+V
Sbjct: 516 ATFEDSSL-RMLYVAAFTAS---MYASTTNRVSKPFNPLLGETFEYARTDGQYRFFTEQV 571
Query: 730 CHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTF---NNI---DAKYRW 783
H PPI A +TE W F G++ + G++ +T +NI + Y W
Sbjct: 572 SHHPPISATWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSW 631
Query: 784 SQPTIVLKNIIAGERYMEPSNQFSIST-STNLKSIIAFKAGGMFSGRSEDVDVSLVNEKG 842
+P + I+ G+ ++ S ++ +T ++ +KA G S + +V + N+
Sbjct: 632 KKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDD 691
Query: 843 QKLGSLKGQWTKEVRD--------------------------LDNGQ-QIWKCGPLVENS 875
+KL L G W + LD + IWK E
Sbjct: 692 KKLWVLGGHWNDSIYGKKVTARGGELTLDRIKTANSATGGPKLDGSKFLIWKAN---ERP 748
Query: 876 EKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR-- 933
+ T F LN + +L PTDSRLRPD R ENG +A K +E KQR
Sbjct: 749 SVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAA 808
Query: 934 --ERRDKGEDAQPQYFKQ-----IKPMKWLPVTGENNYWERRKRHDWSNTKSLW 980
ER KGE+ +P++F Q K + W GE YW +RK HD+ + ++
Sbjct: 809 KKEREQKGEEYRPKWFVQEEHPVTKSLYW-KFNGE--YWNKRKNHDFKDCADIF 859
>CE28126 [I] KOG1737 Oxysterol-binding protein
Length = 627
Score = 171 bits (434), Expect = 4e-42
Identities = 121/408 (29%), Positives = 199/408 (48%), Gaps = 46/408 (11%)
Query: 610 KRRNDIAIPVSTPPSLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKA 669
+RR + + P +L ++ +GK+LS I MP++ +EP+S+LQ ++E EY+ LL
Sbjct: 229 QRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETG 288
Query: 670 ATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVR-EDMGIRLVSEK 728
A + ++++ Y++A+A S S +T KPF PLLGET+E R +D+G R V+E+
Sbjct: 289 AKL--STLEQMCYVAAYAASNYSTTCHRT---NKPFNPLLGETFEFDRMDDLGWRSVTEQ 343
Query: 729 VCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTI 788
V H PP A + E W T +F GK + G + F + + + + T
Sbjct: 344 VSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITT 403
Query: 789 VLKNIIAGERYMEPSNQFSIST-STNLKSIIAFKAGGMFSGRSEDVDVSLVNE-KGQKLG 846
+ NII G+ +++ I+ TN K ++ F FS +V + +G
Sbjct: 404 TVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKY 463
Query: 847 SLKGQWTKEVRDLD----NG--------------QQIWKCGPLVENSEKKYGFTVFTSNL 888
++G W K + L NG ++IW PL +N+EK + FT L
Sbjct: 464 VVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIEL 523
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR--------------E 934
NE ++ + PTDSRLRPD RL ENG EA + KL +E+KQR +
Sbjct: 524 NE----PEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMK 579
Query: 935 RRDKGEDAQPQYFKQIKPMK--WLPVTGENNYWERRKRHDWSNTKSLW 980
+ DK E+ +P +F +++ L + YWE +++ +W ++
Sbjct: 580 KGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 627
>CE26105 [I] KOG1737 Oxysterol-binding protein
Length = 766
Score = 171 bits (434), Expect = 4e-42
Identities = 121/408 (29%), Positives = 199/408 (48%), Gaps = 46/408 (11%)
Query: 610 KRRNDIAIPVSTPPSLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKA 669
+RR + + P +L ++ +GK+LS I MP++ +EP+S+LQ ++E EY+ LL
Sbjct: 368 QRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETG 427
Query: 670 ATMEDDEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVR-EDMGIRLVSEK 728
A + ++++ Y++A+A S S +T KPF PLLGET+E R +D+G R V+E+
Sbjct: 428 AKL--STLEQMCYVAAYAASNYSTTCHRT---NKPFNPLLGETFEFDRMDDLGWRSVTEQ 482
Query: 729 VCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTI 788
V H PP A + E W T +F GK + G + F + + + + T
Sbjct: 483 VSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITT 542
Query: 789 VLKNIIAGERYMEPSNQFSIST-STNLKSIIAFKAGGMFSGRSEDVDVSLVNE-KGQKLG 846
+ NII G+ +++ I+ TN K ++ F FS +V + +G
Sbjct: 543 TVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKY 602
Query: 847 SLKGQWTKEVRDLD----NG--------------QQIWKCGPLVENSEKKYGFTVFTSNL 888
++G W K + L NG ++IW PL +N+EK + FT L
Sbjct: 603 VVQGTWDKSIDMLKVSSWNGNHEKPKLEVDETSLKRIWTANPLPKNAEKMHNFTKLAIEL 662
Query: 889 NEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR--------------E 934
NE ++ + PTDSRLRPD RL ENG EA + KL +E+KQR +
Sbjct: 663 NE----PEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMK 718
Query: 935 RRDKGEDAQPQYFKQIKPMK--WLPVTGENNYWERRKRHDWSNTKSLW 980
+ DK E+ +P +F +++ L + YWE +++ +W ++
Sbjct: 719 KGDKYEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 766
>YDL019c [I] KOG1737 Oxysterol-binding protein
Length = 1283
Score = 170 bits (431), Expect = 9e-42
Identities = 129/389 (33%), Positives = 188/389 (48%), Gaps = 50/389 (12%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
SL L+ VGKD++ +++P++ NEP S+LQ ++E EYS LL +AAT ED ++ L Y+
Sbjct: 897 SLWAVLKSMVGKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTL-YV 955
Query: 684 SAF-ALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEH 742
+AF A SY S T+ + KPF PLLGET+E R D R +E+V H PPI A +TE
Sbjct: 956 AAFTASSYAS----TTKRVAKPFNPLLGETFEYSRPDKQYRFFTEQVSHHPPISATWTES 1011
Query: 743 RDWKCSYTVTPVQKFWGKSIEFTNEGVFELTF----NNIDAKYRWSQPTIVLKNIIAGER 798
W KF G+S + G++ + N + Y W +P + I+ G
Sbjct: 1012 PRWDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNP 1071
Query: 799 YMEPSNQFS-ISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT---- 853
++ + + ++ +T + FKA G S + ++ + N+K QK+ L G W
Sbjct: 1072 QVDNHGEVNVVNHTTGDHCKLYFKARGWRSSGAYEITGEVYNKKKQKVWILGGHWNEAIF 1131
Query: 854 --KEVRDLD-------------NGQQ-------IWKCGPLVENSEKKYGFTVFTSNLNEI 891
K V+D D NG IWK + E+ + T F LN
Sbjct: 1132 AKKVVKDGDLSLEKTRTAASAGNGPTDDGTKFLIWKAN---DRPEEPFNLTPFAITLNAP 1188
Query: 892 TETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERRDKGEDAQPQYFKQ-- 949
LPPTD+RLRPD R E+G EA K +E+KQR R K E+ +Y Q
Sbjct: 1189 QPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRKREENNLEYHPQWF 1248
Query: 950 ------IKPMKWLPVTGENNYWERRKRHD 972
I K+ TG+ YW +R+ HD
Sbjct: 1249 VRDTHPITKAKYWRYTGK--YWVKRRDHD 1275
>At4g22540 [I] KOG1737 Oxysterol-binding protein
Length = 732
Score = 170 bits (430), Expect = 1e-41
Identities = 118/344 (34%), Positives = 167/344 (48%), Gaps = 25/344 (7%)
Query: 609 IKRRNDIAIPVSTPP--SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLL 666
IKRR + P SL ++ NVGKDL+ + +P+ NEP+S LQ E EYS+LL
Sbjct: 339 IKRRTKLPDPAEKEKGVSLWSMIKDNVGKDLTRVCLPVYFNEPISSLQKCFEDLEYSYLL 398
Query: 667 SKAAT--MEDDEVQRLKYISAFALS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIR 723
+A + + R ++AFA+S Y S + KPF PLLGETYE + GIR
Sbjct: 399 DRAYEHGKSGNGLLRALNVAAFAVSGYASTEGRHC----KPFNPLLGETYEADFPEKGIR 454
Query: 724 LVSEKVCHKPPIFAFYTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRW 783
SEKV H P + A + E + WK KFWG+SI+ GV L F++ + ++W
Sbjct: 455 FFSEKVSHHPTVIACHCEGKGWKFWGDTNLRSKFWGRSIQVEPVGVLTLEFDDGEV-FQW 513
Query: 784 SQPTIVLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQ 843
S+ T + NII G+ Y + I + + FK + V+ + + GQ
Sbjct: 514 SKVTSTIYNIILGKLYCDHHGVMQIRGNRQYSCTLKFKEQSILERNPHQVNGFVEDVAGQ 573
Query: 844 KLGSLKGQW--------------TKEVRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLN 889
K ++ G+W +K N +WK N +Y T F LN
Sbjct: 574 KAATIFGKWDDSLYYVAGDGINKSKVSDPASNASLLWKRTKPPPN-VTRYNLTSFAITLN 632
Query: 890 EITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR 933
E+T ++ LPPTDSRLRPD R ENG +A K LE++QR
Sbjct: 633 ELTPGLQEILPPTDSRLRPDQRHLENGEYEKANLEKQRLERRQR 676
>Hs13540513 [I] KOG1737 Oxysterol-binding protein
Length = 916
Score = 166 bits (419), Expect = 2e-40
Identities = 133/417 (31%), Positives = 198/417 (46%), Gaps = 66/417 (15%)
Query: 609 IKRRNDIAIPVSTPPSLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSK 668
+KRR I + +L ++ +G++LS I MP++ NEP+S+LQ L+E EY LL K
Sbjct: 507 VKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDK 566
Query: 669 AATMEDDEVQRLKYISAFALSYMS--IHRQKTRSLRKPFTPLLGETYELVR-EDMGIRLV 725
A V+++ ++AF++S S +HR + KPF P+LGET+EL R +DMG+R +
Sbjct: 567 AVHC-TSSVEQMCLVAAFSVSSYSTTVHR-----IAKPFNPMLGETFELDRLDDMGLRSL 620
Query: 726 SEKVCHKPPIFAFYT-EHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWS 784
E+V H PP A Y W +T KF GK I G L F Y W
Sbjct: 621 CEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWR 680
Query: 785 QPTIVLKNIIAGERYMEPSNQFSI-STSTNLKSIIAFKAGGMFSGRSEDVDVSLVNE-KG 842
+ T + NII G+ +++ S I + TN + + F FS + +V++ +G
Sbjct: 681 KSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQG 740
Query: 843 QKLGSLKGQWTKEVR-----------DLDNGQQ-----------IWKCGPLVENSEKKYG 880
+ L G W +++ +G+Q +WK PL EN+E Y
Sbjct: 741 KAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYY 800
Query: 881 FTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERR---- 936
F+ LNE ++ + PTDSRLRPD RL E G EA K LE+KQR R
Sbjct: 801 FSELALTLNE----HEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRL 856
Query: 937 -------------DKGEDA-QPQYFKQIKPMKWLPVTGE------NNYWERRKRHDW 973
+K DA P +F++ + P+TGE YWE +++ DW
Sbjct: 857 EACGPGSSCSSEEEKEADAYTPLWFEK----RLDPLTGEMACVYKGGYWEAKEKQDW 909
>Hs4505531 [I] KOG1737 Oxysterol-binding protein
Length = 807
Score = 165 bits (418), Expect = 3e-40
Identities = 131/402 (32%), Positives = 190/402 (46%), Gaps = 57/402 (14%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
+L ++ +GK+LS I MP++ NEP+S+LQ L+E EY LL +AA E + +++L Y+
Sbjct: 418 NLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCE-NSLEQLCYV 476
Query: 684 SAFALSYMSIHRQKTRSLRKPFTPLLGETYELVR-EDMGIRLVSEKVCHKPPIFAFYTEH 742
+AF +S S +T KPF PLLGET+EL R E+ G R + E+V H PP A + E
Sbjct: 477 AAFTVSSYSTTVFRT---SKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAES 533
Query: 743 RD-WKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME 801
++ W + KF GK + G F+ Y W + T + NII G+ +++
Sbjct: 534 KNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWID 593
Query: 802 PSNQFSI-----STSTNLKSI--------IAFKAGGMFSGRSEDVDVSLVNEKGQKLGSL 848
S + I NLK + +A K G + S V +L+ +K+
Sbjct: 594 QSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMECF 653
Query: 849 KGQWTKEVRDLDNGQQ----------IWKCGPLVENSEKKYGFTVFTSNLNEITETEKDH 898
K Q D Q+ +WK PL +N+E Y F+ LN +
Sbjct: 654 KVQPVIGENGGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLN----AWESG 709
Query: 899 LPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQRERRDK--------GEDAQPQ----- 945
PTDSRLRPD RL ENG EA K LE+KQR R K ED P
Sbjct: 710 TAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTPYDPYKA 769
Query: 946 -YFKQIKPMKWLPVTGE------NNYWERRKRHDWSNTKSLW 980
+F++ K PVT E YWE +++ DWS+ ++
Sbjct: 770 LWFERKKD----PVTKELTHIYRGEYWECKEKQDWSSCPDIF 807
Score = 51.2 bits (121), Expect = 8e-06
Identities = 43/187 (22%), Positives = 78/187 (40%), Gaps = 15/187 (8%)
Query: 214 PSPGQTTPSTISNVGTSNGPNTNS-----PVPIKPLSPSSTSATDHDLKNSKGFQGYLLK 268
P G + + ++ GP P P P S S +G+ L
Sbjct: 41 PGSGAASGTVVAAAAGGPGPGAGGVAAAGPAPAPPTGGSGGSGAGGSGSAREGW----LF 96
Query: 269 KKRKKLQGFTKRFFKLDIKFGILSYYLNSKSPV---CRGEIVVPLSSISANKQTKLIIID 325
K ++G+ +R+F L G+LSYY SK+ + CRG I + ++I+ II +
Sbjct: 97 KWTNYIKGYQRRWFVLSN--GLLSYY-RSKAEMRHTCRGTINLATANITVEDSCNFIISN 153
Query: 326 SGMEIWVMKARDEKDWELWISMIESCFKQDAPTTSQDHESHNVVIPPDNDTTAFFRNLTS 385
G + + +KA E + + W++ +E + ++ ES + D T L +
Sbjct: 154 GGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRT 213
Query: 386 LRKRIEE 392
L ++E+
Sbjct: 214 LSSKVED 220
>Hs19718743 [T] KOG2209 Oxysterol-binding protein
Length = 927
Score = 161 bits (407), Expect = 5e-39
Identities = 122/409 (29%), Positives = 186/409 (44%), Gaps = 92/409 (22%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
S+ LRK +G +LS I+MP+ NEP+S LQ L+E E+++L+ KA+++ D V+R++ +
Sbjct: 548 SIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSL-SDPVERMQCV 606
Query: 684 SAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTE-- 741
+AFA+S ++ ++T KP V H PPI AF+ E
Sbjct: 607 AAFAVSAVASQWERT---GKPL-----------------------VSHHPPISAFHAEGL 640
Query: 742 HRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME 801
+ D+ ++ P KFWGKS+E +G L + Y W+ PT + NII G+ ++E
Sbjct: 641 NNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIE 700
Query: 802 P-SNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT------- 853
N I+ T K ++ FK G+F V+ + ++ +KL +L G+WT
Sbjct: 701 QYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVD 760
Query: 854 ------------KEVRDLDNGQQ--------------------------IWKCGPLVENS 875
K + N +Q +W+ P NS
Sbjct: 761 PATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNS 820
Query: 876 EKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAEQMKLSLEQKQR-- 933
+ Y FT F LNE+ + + +P TD RLRPDIR ENG I +A + K LE+KQR
Sbjct: 821 AQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAA 880
Query: 934 --ERRDKGEDAQPQYFKQIKPMKWLPVTGENNYWERRKRHDWSNTKSLW 980
R ED + ++F Q G N Y DW + S W
Sbjct: 881 RKNRSKSEEDWKTRWFHQ----------GPNPY---NGAQDWIYSGSYW 916
>7291708 [T] KOG2209 Oxysterol-binding protein
Length = 455
Score = 154 bits (388), Expect = 8e-37
Identities = 88/235 (37%), Positives = 137/235 (57%), Gaps = 7/235 (2%)
Query: 624 SLLGFLRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYI 683
S+ L+ +GKDLS I+MP+ LNEP+S LQ L E EY+ LL++AA E R+KY+
Sbjct: 26 SIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHP-ADRMKYV 84
Query: 684 SAFALSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHR 743
+AFA+S ++ + ++ L KPF PLLGETYEL + D R+V E+V H PP+ AF+ E +
Sbjct: 85 AAFAVSALASNWER---LGKPFNPLLGETYELQKGDY--RIVCEQVSHHPPVSAFHAESK 139
Query: 744 DWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPS 803
D+K T++P KFWGKS+E +G + F + Y W+ + NII G ++E
Sbjct: 140 DFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQY 199
Query: 804 NQFSIST-STNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKEVR 857
+ I+ +T + + FK+ G + V+ + + L L G+WT+ ++
Sbjct: 200 GKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFIK 254
Score = 65.5 bits (158), Expect = 4e-10
Identities = 46/135 (34%), Positives = 64/135 (47%), Gaps = 19/135 (14%)
Query: 858 DLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLP--PTDSRLRPDIRLYEN 915
D+ + +W C P N + Y FT F LN + K L PTDSRLRPDI E
Sbjct: 328 DIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEE 387
Query: 916 GIITEAEQMKLSLEQKQRERRDK-----GEDAQPQYFK-----QIKPMKWLPVTGENNYW 965
G + A + K LE+KQR R + +D P++FK K WL G YW
Sbjct: 388 GNLDGASKEKTRLEEKQRHTRKQRKSTNSDDWSPRWFKYATNPHTKIDDWLYSGG---YW 444
Query: 966 ERRKRHDWSNTKSLW 980
+R+ + NT +++
Sbjct: 445 DRK----YDNTDTIF 455
>At5g02100 [I] KOG1737 Oxysterol-binding protein
Length = 453
Score = 137 bits (345), Expect = 8e-32
Identities = 99/347 (28%), Positives = 173/347 (49%), Gaps = 29/347 (8%)
Query: 629 LRKNVGKDLSS-ISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFA 687
++K +G D++S +++P+ + EP+++LQ ++E EYS+LL A ED + R+ Y S++A
Sbjct: 73 MQKYIGSDVTSMVTLPVIIFEPMTMLQKMAELMEYSYLLDMADKTEDPYM-RMVYASSWA 131
Query: 688 LSYMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWKC 747
+S +++ KPF P+LGETYE+ + GI ++E+VCH PP+ A + E+ +
Sbjct: 132 ISVYYAYQRTW----KPFNPILGETYEMTNHN-GINFIAEQVCHHPPMSAGHAENEHFAY 186
Query: 748 SYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME-PSNQF 806
T KF G SI+ G +T P + N+I G +++ P
Sbjct: 187 DCTSKLKTKFLGNSIDVYPVGRTRVTLKRDGVVLDLVPPLTKVHNLIFGRTWVDSPGEMV 246
Query: 807 SISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKEVR----DLDNG 862
+ +T K ++ F+ G F +VD + N + + G+W + + D +
Sbjct: 247 MTNLTTGDKVVLYFQPCGWFGSGRYEVDGYVYNSAEEPKMLMTGKWNESLSYQPCDAEGE 306
Query: 863 -------QQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYEN 915
+++WK +N KY +T F +N +T L +DSRLRPD E
Sbjct: 307 PLPGTELKEVWKVAEAPKND--KYQYTHFAHKINSF-DTAPKKLLSSDSRLRPDRYALEM 363
Query: 916 GIITEAEQMKLSLEQKQR----ERRDKGEDAQPQYF---KQIKPMKW 955
G ++++ K SLE +QR R +KG+ P++F +++ P W
Sbjct: 364 GDMSKSGFEKSSLEDRQRAEKKSREEKGQKFAPKWFDETEEVTPTPW 410
>At3g09300 [I] KOG1737 Oxysterol-binding protein
Length = 458
Score = 130 bits (327), Expect = 1e-29
Identities = 97/337 (28%), Positives = 169/337 (49%), Gaps = 28/337 (8%)
Query: 629 LRKNVGKDLSS-ISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFA 687
++K +G D++S +++P+ + EP+++LQ ++E EYS LL A ED + R+ Y S++A
Sbjct: 78 MQKYIGSDVTSMVTLPVIIFEPMTMLQKMAELMEYSHLLDMADKTEDPYL-RMVYASSWA 136
Query: 688 LS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWK 746
+S Y + R KPF P+LGETYE+ + G+ +SE+V H PP+ A + E+ +
Sbjct: 137 ISVYYAFQRTW-----KPFNPILGETYEMANYN-GVNFISEQVSHHPPMSAGHAENEHFT 190
Query: 747 CSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME-PSNQ 805
T KF G SI+ G +T P + N+I G +++ P
Sbjct: 191 YDCTSKLKTKFLGNSIDVYPVGRTRVTLKRDGVVLDLVPPLTKVHNLIFGRTWVDSPGEM 250
Query: 806 FSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKEV--RDLDNG- 862
+ +T K ++ F+ G F +VD + N + + G+W + + + D
Sbjct: 251 IMTNQTTGDKVVLYFQPCGWFGSGRYEVDGYVYNASEEPKILMTGKWNESMSYQPCDGEG 310
Query: 863 --------QQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYE 914
+++WK + + + KY +T F +N +T L P+DSRLRPD E
Sbjct: 311 EPLPGTELKEVWKLADVPK--DDKYQYTHFAHKINSF-DTAPKKLLPSDSRLRPDRYALE 367
Query: 915 NGIITEAEQMKLSLEQKQ----RERRDKGEDAQPQYF 947
G ++++ K S+E++Q R R +KG+ P++F
Sbjct: 368 MGDMSKSGYEKSSMEERQRAEKRTREEKGQAFTPKWF 404
>At5g59420 [I] KOG1737 Oxysterol-binding protein
Length = 457
Score = 126 bits (316), Expect = 2e-28
Identities = 99/348 (28%), Positives = 170/348 (48%), Gaps = 31/348 (8%)
Query: 629 LRKNVGKDLSS-ISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFA 687
++K +G D++S +++P+ + EP+++LQ ++E EYS LL +A ED + RL Y S++A
Sbjct: 73 MQKYIGSDITSMVTLPVVIFEPMTMLQKMAEIMEYSHLLDQADECEDPYL-RLVYASSWA 131
Query: 688 LS-YMSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRDWK 746
+S Y + R KPF P+LGETYE+V GI +SE+V H PP+ A + E+ +
Sbjct: 132 ISVYYAFQR-----TWKPFNPILGETYEMVNHG-GISFISEQVSHHPPMSAGHAENEHFI 185
Query: 747 CSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYME-PSNQ 805
T K G S++ G +T P + N+I G +++ P
Sbjct: 186 YDITSKLKTKLLGNSVDVYPVGRTRVTLKKDGVVLDLVPPLTKIHNLIFGRTWVDSPGEM 245
Query: 806 FSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKEVR----DLDN 861
+ +T K ++ F+ G F +VD + + + + G+W +++ D +
Sbjct: 246 VMTNLTTGDKVVLYFQPCGWFGSGRYEVDGYVYSAAEEPKIMMTGKWNEKMSYQPCDAEG 305
Query: 862 G-------QQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYE 914
+++W + +N +Y T F +N +T L +DSR+RPD E
Sbjct: 306 EPLPGTELKEVWHLADVPKNDNFQY--THFAHKINSF-DTAPAKLLASDSRIRPDRYSLE 362
Query: 915 NGIITEAEQMKLSLEQKQ----RERRDKGEDAQPQYF---KQIKPMKW 955
G +++A K SLE++Q R R KG+ P++F +I P W
Sbjct: 363 QGDLSKAGSEKHSLEERQRAEKRTRETKGQKFTPRWFDLTDEITPTPW 410
>Hs22035609 [T] KOG2210 Oxysterol-binding protein
Length = 811
Score = 110 bits (274), Expect = 1e-23
Identities = 96/332 (28%), Positives = 156/332 (46%), Gaps = 21/332 (6%)
Query: 624 SLLGFLRKNV--GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLK 681
SL+ L K + G DLS + +P + EP S L LS+ + ++ LLS+AA +E+D R+K
Sbjct: 301 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAA-VEEDAYSRMK 359
Query: 682 YISAFALSYMSIHRQKTRSLRKPFTPLLGETYELV----REDMGIRLVSEKVCHKPPIFA 737
+ + Y+S +K + ++KP+ P+LGET+ + D ++E+V H PP+ A
Sbjct: 360 LVLRW---YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSA 416
Query: 738 FYTEHR-DWKC-SYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIA 795
F+ +R D C S ++T +F+G S+ +G LTF N Y + P K I+
Sbjct: 417 FHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILY 476
Query: 796 GERYMEPSNQFSIS-TSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQK-LGSLKGQWT 853
G +E + +I N ++ + FK F G + +S G++ L SL G W
Sbjct: 477 GTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWD 536
Query: 854 KEVRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLY 913
++V + G ++ T L E TE E + L + R
Sbjct: 537 RDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERL------WQHVTRAI 590
Query: 914 ENGIITEAEQMKLSLEQKQRER-RDKGEDAQP 944
G A Q K +LE+ QR+R R++ E P
Sbjct: 591 SKGDQHRATQEKFALEEAQRQRARERQESLMP 622
>Hs14149740 [T] KOG2210 Oxysterol-binding protein
Length = 879
Score = 110 bits (274), Expect = 1e-23
Identities = 96/332 (28%), Positives = 156/332 (46%), Gaps = 21/332 (6%)
Query: 624 SLLGFLRKNV--GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLK 681
SL+ L K + G DLS + +P + EP S L LS+ + ++ LLS+AA +E+D R+K
Sbjct: 369 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAA-VEEDAYSRMK 427
Query: 682 YISAFALSYMSIHRQKTRSLRKPFTPLLGETYELV----REDMGIRLVSEKVCHKPPIFA 737
+ + Y+S +K + ++KP+ P+LGET+ + D ++E+V H PP+ A
Sbjct: 428 LVLRW---YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSA 484
Query: 738 FYTEHR-DWKC-SYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIA 795
F+ +R D C S ++T +F+G S+ +G LTF N Y + P K I+
Sbjct: 485 FHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILY 544
Query: 796 GERYMEPSNQFSIS-TSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQK-LGSLKGQWT 853
G +E + +I N ++ + FK F G + +S G++ L SL G W
Sbjct: 545 GTMTLELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGEEVLASLSGHWD 604
Query: 854 KEVRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLY 913
++V + G ++ T L E TE E + L + R
Sbjct: 605 RDVFIKEEGSGSSALFWTPSGEVRRQRLRQHTVPLEEQTELESERL------WQHVTRAI 658
Query: 914 ENGIITEAEQMKLSLEQKQRER-RDKGEDAQP 944
G A Q K +LE+ QR+R R++ E P
Sbjct: 659 SKGDQHRATQEKFALEEAQRQRARERQESLMP 690
>Hs18079218 [T] KOG2210 Oxysterol-binding protein
Length = 889
Score = 108 bits (270), Expect = 4e-23
Identities = 111/360 (30%), Positives = 174/360 (47%), Gaps = 40/360 (11%)
Query: 624 SLLGFLRKNV--GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLK 681
SL+ L K V G DLS + +P + EP S L LS+ + ++ LS+AA +E++ RLK
Sbjct: 405 SLIWTLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAA-LEENPYFRLK 463
Query: 682 YISAFALSYMSIHRQKTRSLRKPFTPLLGETYELV----REDMGIRLVSEKVCHKPPIFA 737
+ + Y+S +K + L+KP+ P+LGET+ + R + ++E+V H PPI A
Sbjct: 464 KVVKW---YLSGFYKKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISA 520
Query: 738 FYTEHR-DWKC-SYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIA 795
FY +R D C S ++ KF+G S+ EG LTF N Y + P K I+
Sbjct: 521 FYVSNRKDGFCLSGSILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILY 580
Query: 796 GERYMEPSNQFSIS-TSTNLKSIIAFKAGGMFSGRSEDVD-VSLVNEKGQK-LGSLKGQW 852
G +E +I+ T +I+ FK F G S+ V+ +S + G++ L +L+G W
Sbjct: 581 GTMTLELGGTVNITCQKTGYSAILEFKL-KPFLGSSDCVNQISGKLKLGKEVLATLEGHW 639
Query: 853 TKEV----RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRP 908
EV + DN + W P + K++ T E + E + L R+
Sbjct: 640 DSEVFITDKKTDNSEVFWNPTPDI----KQWRLIRHTVKFEEQGDFESEKL---WQRVTR 692
Query: 909 DIRLYENGIITEAEQMKLSLEQKQ----RERRDKGEDAQPQYFKQIKPMKWLPVTGENNY 964
I + TEA Q K LE+ Q R+R+ K E+ + F+ P+TGE +Y
Sbjct: 693 AINAKDQ---TEATQEKYVLEEAQRQAARDRKTKNEEWSCKLFELD------PLTGEWHY 743
>CE06680 [T] KOG2210 Oxysterol-binding protein
Length = 751
Score = 98.6 bits (244), Expect = 4e-20
Identities = 90/353 (25%), Positives = 159/353 (44%), Gaps = 25/353 (7%)
Query: 624 SLLGFLRKNV--GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLK 681
SL+ L K + G DLS + +P + EP S L+ L++ + ++ L+S+A E D QR+
Sbjct: 228 SLIWTLLKQIRPGMDLSKVVLPTFILEPRSFLEKLADYYYHADLISEAVA-EPDPFQRIV 286
Query: 682 YISAFALSYMSIHRQKTRSLRKPFTPLLGETYELVRE---DMGIRLVSEKVCHKPPIFAF 738
++ F ++S +K + L+KP+ P+LGET+ E ++E+V H PP+ +
Sbjct: 287 KVTKF---FLSGFYKKPKGLKKPYNPILGETFRCKWEHPDGSTTFYMAEQVSHHPPVSSL 343
Query: 739 YTEHR--DWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAG 796
+ +R + S T+ K++G S+ G LT N+ Y + P K I+ G
Sbjct: 344 FITNRKAGFNISGTILAKSKYYGNSLSAILAGKLRLTLLNLGETYIVNLPYANCKGIMIG 403
Query: 797 ERYMEPSNQFSIS-TSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKE 855
ME + +I T ++ + FK M G ++ S + +L S++G W
Sbjct: 404 TMTMELGGEVNIECEKTGYRTTLDFKLKPMLGGAYNQIEGS-IKYGSDRLASIEGAWDGV 462
Query: 856 VR--DLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLY 913
+R D +++W P V K + N++E E E L R
Sbjct: 463 IRIKGPDGKKELWNPTPEV----IKTRLPRYEINMDEQGEWESAKL------WRHVTEAI 512
Query: 914 ENGIITEAEQMKLSLEQKQRERRDKGEDAQPQYFKQIKPMKWLPVTGENNYWE 966
N +A + K +LE QR R G + ++FK+ ++ + + W+
Sbjct: 513 SNEDQYKATEEKTALENDQRARAKSGIPHETKFFKKQHGDDYVYIHADYRPWD 565
>SPCC23B6.01c [T] KOG2210 Oxysterol-binding protein
Length = 489
Score = 93.6 bits (231), Expect = 1e-18
Identities = 92/354 (25%), Positives = 159/354 (43%), Gaps = 45/354 (12%)
Query: 629 LRKNVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFAL 688
LR N+ DLS ++ P + EP S+L+ ++ + LL D E++ L +
Sbjct: 38 LRPNM--DLSKVTFPTFVLEPKSMLERITNFMSHPDLLLNVQKTADPEMRFLDVVRF--- 92
Query: 689 SYMSIHRQKTRSLRKPFTPLLGETYE-------------LVREDMGIRL-VSEKVCHKPP 734
YMS + R ++KP P+LGET+ +++ GI + +E+VCH PP
Sbjct: 93 -YMSGWHIRPRGVKKPLNPILGETFTGFWKFPPSNSKDPNLQKLHGIAVYAAEQVCHHPP 151
Query: 735 IFAFYTEHRDWKCSY--TVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKN 792
I A++ ++K V P +F G S EG+ + ++D +Y +QP + +
Sbjct: 152 ISAYFYLCPEYKVRIDGVVKPRSRFLGNSAASIMEGIASIKLQDLDEEYLITQPNVYARG 211
Query: 793 IIAGERYMEPSNQFSI-STSTNLKSIIAFKAGGMFSGRSEDVDVSLVN-EKGQKLGSLKG 850
I+ G+ +E + ++ T+L++ I FK G SG + + G+ L + G
Sbjct: 212 ILFGKMRLELGDHVTVRCPKTDLQADIEFKVKGFISGTYNSIAGKVKRVSTGEVLYKISG 271
Query: 851 QWTKE--VRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHL--PPTDSRL 906
+W E V + G+ PL++ S K + V L E E E L + +
Sbjct: 272 KWDSEMSVESVKTGE----TRPLLDVS-KHDVYLVSARPLEEQGERESQRLWYKTCQAVI 326
Query: 907 RPDIRLYENGIITEAEQMKLSLEQKQRERRDKGE----DAQPQYFKQIKPMKWL 956
D T A + K ++E +QRE + E +P+YFK I P +++
Sbjct: 327 ARD--------QTTATETKSAIEDRQREEAKQREIENVQWKPKYFKMIAPEEYI 372
>Hs22066714 [T] KOG2210 Oxysterol-binding protein
Length = 578
Score = 85.9 bits (211), Expect = 3e-16
Identities = 61/186 (32%), Positives = 100/186 (52%), Gaps = 12/186 (6%)
Query: 624 SLLGFLRKNV--GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLK 681
SL+ L K + G DLS + +P + EP S L LS+ + ++ LLS+AA +E+D R+K
Sbjct: 369 SLMWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAA-VEEDAYSRMK 427
Query: 682 YISAFALSYMSIHRQKTRSLRKPFTPLLGETYELV----REDMGIRLVSEKVCHKPPIFA 737
+ + Y+S +K + ++KP+ P+LGET+ + D ++E+V H PP+ A
Sbjct: 428 LVLRW---YLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSA 484
Query: 738 FYTEHR-DWKC-SYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIA 795
F+ +R D C S ++T +F+G S+ +G LTF N Y + P K I+
Sbjct: 485 FHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILY 544
Query: 796 GERYME 801
G +E
Sbjct: 545 GTMTLE 550
>YHR001w [T] KOG2210 Oxysterol-binding protein
Length = 437
Score = 71.2 bits (173), Expect = 7e-12
Identities = 79/340 (23%), Positives = 155/340 (45%), Gaps = 39/340 (11%)
Query: 634 GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSI 693
G DLS I++P + E S+L+ ++ ++ +L +A + +D +QR + A+ L+ I
Sbjct: 61 GCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDG-LQRFVKVVAWYLAGWHI 119
Query: 694 HRQKTRSLRKPFTPLLGETY----ELVREDMGIRLVSEKVCHKPPIFAFY--TEHRDWKC 747
R+++KP P+LGE + +L + ++E+ H PP A++ + +
Sbjct: 120 G---PRAVKKPLNPILGEHFTAYWDLPNKQQAF-YIAEQTSHHPPESAYFYMIPESNIRV 175
Query: 748 SYTVTPVQKFWGKSIEFTNEGVFELTFNNI-DA-----KYRWSQPTIVLKNIIAGERYME 801
V P KF G S EG+ L F +I DA KY SQP + + I+ G+ +E
Sbjct: 176 DGVVVPKSKFLGNSSAAMMEGLTVLQFLDIKDANGKPEKYTLSQPNVYARGILFGKMRIE 235
Query: 802 PSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWT-----KEV 856
+ I + I FK G SG + ++ ++ + G++ + G+W K++
Sbjct: 236 LGDHMVIM-GPKYQVDIEFKTKGFISGTYDAIEGTIKDYDGKEYYQISGKWNDIMYIKDL 294
Query: 857 RDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENG 916
R+ + + + + ++ + + L E E E L ++ + + ++
Sbjct: 295 REKSSKKTV------LFDTHQHFPLAPKVRPLEEQGEYESRRL---WKKVTDALAVRDHE 345
Query: 917 IITEAEQMKLSLEQKQRE----RRDKGEDAQPQYFKQIKP 952
+ TE K +E +QRE R + G + + F++ +P
Sbjct: 346 VATEE---KFQIENRQRELAKKRAEDGVEFHSKLFRRAEP 382
>YKR003w [T] KOG2210 Oxysterol-binding protein
Length = 448
Score = 70.5 bits (171), Expect = 1e-11
Identities = 76/332 (22%), Positives = 145/332 (42%), Gaps = 23/332 (6%)
Query: 634 GKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMSI 693
G DL+ I++P + E S+L+ ++ ++ L +A + E D ++R Y+ + L+ I
Sbjct: 61 GCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHS-EKDPLKRFLYVMKWYLAGWHI 119
Query: 694 HRQKTRSLRKPFTPLLGE---TYELVREDMGIRLVSEKVCHKPPIFAFY--TEHRDWKCS 748
++++KP P+LGE Y + +SE+ H PP A++ +
Sbjct: 120 ---APKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPPECAYFYMIPESSIRVD 176
Query: 749 YTVTPVQKFWGKSIEFTNEGVFELTF------NNIDAKYRWSQPTIVLKNIIAGERYMEP 802
V P +F G S +G L F N KY +QP + ++ I+ G+ +E
Sbjct: 177 GVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIEL 236
Query: 803 SNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQKLGSLKGQWTKEVRDLDNG 862
+ I S N ++ I FK G G + ++ ++ + G + G+W +V L +
Sbjct: 237 GDHMIIK-SPNFQADIEFKTKGYVFGTYDAIEGTVKDYDGNAYYEISGKW-NDVMYLKDL 294
Query: 863 QQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLRPDIRLYENGIITEAE 922
+Q + ++ K+ L+E E E L + D N + E
Sbjct: 295 KQPRSSPKVFLDTHKESPLRPKVRPLSEQGEYESRKL----WKKVTDALAVRNHPVATEE 350
Query: 923 QMKLSLEQKQ--RERRDKGEDAQPQYFKQIKP 952
+ ++ Q+Q ++R + G + P+ F++ KP
Sbjct: 351 KFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKP 382
>YPL145c [T] KOG2210 Oxysterol-binding protein
Length = 434
Score = 62.4 bits (150), Expect = 3e-09
Identities = 81/354 (22%), Positives = 145/354 (40%), Gaps = 54/354 (15%)
Query: 636 DLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDD---------------EVQRL 680
DLSS+S P + P+S+ + E+ L + + + DD E+ R+
Sbjct: 23 DLSSLSAPPFILSPISLTEFSQYWAEHPELFLEPSFINDDNYKEHCLIDPEVESPELARM 82
Query: 681 KYISAFALSYM-SIHRQKTRSL---RKPFTPLLGETYELVREDMG------IRLVSEKVC 730
++ + +S + S + + SL +KP P LGE + E+ L+SE+V
Sbjct: 83 LAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVS 142
Query: 731 HKPPIFAFYTEHRDWKCSYT-VTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIV 789
H PP+ AF + K ++ + KS+ T + + D Y + P +
Sbjct: 143 HHPPVTAFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKDESYLVTPPPLH 202
Query: 790 LKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLV------NEKGQ 843
++ I+ ++E + I +ST L +I F G FSG+ + +K +
Sbjct: 203 IEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGYFSGKKNSFKARIYKDSKDSKDKEK 262
Query: 844 KLGSLKGQWTKEVRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTD 903
L ++ GQW+ + + ++ E S Y + + E+ H P +
Sbjct: 263 ALYTISGQWSGSSKIIKANKK--------EESRLFYDAARIPAEHLNVKPLEEQH--PLE 312
Query: 904 SR-----LRPDIRLYENGIITEAEQMKLSLEQKQRERRD----KGEDAQPQYFK 948
SR + I+L + +I + K LE+ QRE R KG Q ++FK
Sbjct: 313 SRKAWYDVAGAIKLGDFNLIAKT---KTELEETQRELRKEEEAKGISWQRRWFK 363
>Hs21735588 [I] KOG1737 Oxysterol-binding protein
Length = 611
Score = 60.8 bits (146), Expect = 1e-08
Identities = 36/78 (46%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
Query: 598 QDLSP-LPINKTIKRRNDIAIPVSTPPS----LLGFLRKNVGKDLSSISMPISLNEPVSI 652
Q L P L + K R +P P S L LR N+GKDLS ++MP+ LNEP++
Sbjct: 465 QTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNT 524
Query: 653 LQVLSEAFEYSWLLSKAA 670
LQ L E EYS LL KAA
Sbjct: 525 LQRLCEELEYSELLDKAA 542
>Hs21735586 [I] KOG1737 Oxysterol-binding protein
Length = 642
Score = 60.8 bits (146), Expect = 1e-08
Identities = 36/78 (46%), Positives = 44/78 (56%), Gaps = 5/78 (6%)
Query: 598 QDLSP-LPINKTIKRRNDIAIPVSTPPS----LLGFLRKNVGKDLSSISMPISLNEPVSI 652
Q L P L + K R +P P S L LR N+GKDLS ++MP+ LNEP++
Sbjct: 496 QTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNT 555
Query: 653 LQVLSEAFEYSWLLSKAA 670
LQ L E EYS LL KAA
Sbjct: 556 LQRLCEELEYSELLDKAA 573
>Hs19923812 [T] KOG2210 Oxysterol-binding protein
Length = 764
Score = 59.7 bits (143), Expect = 2e-08
Identities = 49/188 (26%), Positives = 83/188 (44%), Gaps = 15/188 (7%)
Query: 182 GTNGKRPLNYSQTSFKDPSLSSLAKSNSNPFAPSPGQTTPSTISNVGTSNGPNTNSPVPI 241
GT+G N S S S + S+P G+ S + G G + +SP +
Sbjct: 7 GTDGGGGSNSSSRSS-----SRATSAGSSPSCSLAGRGVSSRSAAAGLGGGGSRSSPGSV 61
Query: 242 KPLSPSSTSATDHDLKNSKGFQGYLLKKKRKKLQGFTKRFFKLDIKFGILSYYLNSKSPV 301
SPS + +G +L K LQG+ R+F LD + GIL Y++N +S
Sbjct: 62 AA-SPSGGGGR----RREPALEG-VLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKH 115
Query: 302 CRGEIVVPLS----SISANKQTKLIIIDSGMEIWVMKARDEKDWELWISMIESCFKQDAP 357
+ V+ LS S+S L++ + E++ ++A D K+ + W++ + +C K
Sbjct: 116 QKPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLRACAKYHME 175
Query: 358 TTSQDHES 365
S+ S
Sbjct: 176 MNSKSAPS 183
>CE08539 [T] KOG2210 Oxysterol-binding protein
Length = 676
Score = 59.7 bits (143), Expect = 2e-08
Identities = 78/351 (22%), Positives = 144/351 (40%), Gaps = 54/351 (15%)
Query: 632 NVGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYM 691
+VG DL+ +++P + E S+L++ ++ F + L + E + + + + S+
Sbjct: 324 SVGMDLTKVTLPTFILERRSLLEMYADFFAHPDLFIATNGNDSAEKRMIAVVRYYLNSFY 383
Query: 692 SIHRQKTRSLRKPFTPLLGETYELV--------------------REDMGIRLVSEKVCH 731
+ +K+ +KP+ +LGET+ ++ + ++E+V H
Sbjct: 384 AA--RKSGVAKKPYNAILGETFRCRYSVPNSSLSGKKTESGPWPGSDEKQLTFIAEQVSH 441
Query: 732 KPPIFAFYTEHRDWKCSYT--VTPVQKFWGKSIEFTNEGVFELTFNNI-DAKYRWSQPTI 788
PPI AFY E S+ + F G SI + G LT +N D +Y + P+
Sbjct: 442 HPPISAFYAEMPSEGISFNAHIYTKSSFLGLSIGVASIGEGILTLHNYGDEQYTITFPSG 501
Query: 789 VLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQK-LGS 847
++I++ + T ++ I F F G+ + S+ + +K + +
Sbjct: 502 YGRSIMSTPWFEFGGKVKVECEKTGYRADIEFLTKPFFGGKPHRIQGSICRDGAKKPVLT 561
Query: 848 LKGQWTKEVRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPTDSRLR 907
L+G+W NG K +N E +Y F ++ E +K+ +P R
Sbjct: 562 LRGEW--------NGTMYAK----TQNGE-EYVFV----DVKAKPEVKKECVPVMQQGKR 604
Query: 908 PDIRLYEN-------GIITEAEQMKLSLEQKQR----ERRDKGEDAQPQYF 947
RL+ + I A K +EQ+QR ER + GE P F
Sbjct: 605 ESRRLWRHVTAALLRNRIQTATTSKRFIEQRQRKEAKERLESGEKWTPLLF 655
>SPBC1271.12 [T] KOG2210 Oxysterol-binding protein
Length = 388
Score = 58.9 bits (141), Expect = 4e-08
Identities = 56/246 (22%), Positives = 107/246 (42%), Gaps = 12/246 (4%)
Query: 620 STPPSLLGFLRK--NVGKDLSSISMPISLNEPVSILQVLSEAFEYSWL---LSKAATMED 674
+T + L FL+ DLSS++ P + S+++ + E+ L L + T +
Sbjct: 22 TTKSTWLSFLKSIATFSGDLSSLTAPSFILSSTSLIEYSAYWAEHPELFISLPRGETPLE 81
Query: 675 DEVQRLKYISAFALSYMSIHRQKTRSLRKPFTPLLGETYE-LVREDMG--IRLVSEKVCH 731
++ K+ ++ + + ++ S +KP P+LGE + D+G L SE+V H
Sbjct: 82 RQLLVTKWFASTLKNQYAARNERYGSEKKPLNPILGELFTGKWNTDIGEDTELTSEQVSH 141
Query: 732 KPPIFAFYTEHRDWKCSYTVTPVQK--FWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIV 789
PPI A++ ++ K F G I G L + Y + P +
Sbjct: 142 HPPITAYHIYNKKAGVRLEGYNGHKSGFSGPQIHVKQIGHARLILEPHNEVYYITFPLVT 201
Query: 790 LKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLVN--EKGQKLGS 847
L+ + G Y+E + I +++ + I + G F+G+ ++VN K + +
Sbjct: 202 LEGLWYGSPYIELGKKSYIISTSGYLTTIEYSGKGYFTGKKNTFKATIVNAKTKSEPIYR 261
Query: 848 LKGQWT 853
++G WT
Sbjct: 262 IEGSWT 267
>At4g25850 [T] KOG2210 Oxysterol-binding protein
Length = 378
Score = 58.5 bits (140), Expect = 5e-08
Identities = 84/345 (24%), Positives = 144/345 (41%), Gaps = 49/345 (14%)
Query: 634 GKDLSSISMPISLNEPVSILQVLSEAFEYSWL---LSKAATMEDDEVQRLKYISAFALSY 690
G DL++ +P LN P S LQ E YS++ L + D ++RLK + + +S
Sbjct: 40 GSDLTNFQLPPQLNLPRSQLQCYGEMV-YSFVGQDLLGECSRRDLPIERLKSVVTWNIST 98
Query: 691 MSIHRQKTRSLRKPFTPLLGETYELVREDMGIRLVSEKVCHKPPIFAFYTEHRD------ 744
+ + P+ +LGET+ + + I +++E+V H PP+ A + H
Sbjct: 99 L----RPVVFGMSPYNSVLGETHHV--SNGHINVIAEQVVHHPPVSALHATHEQENIDVT 152
Query: 745 WKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTIVLKNIIAGERYMEPSN 804
W C Y TP KF G ++ +G + N Y QP ++++ + A Y
Sbjct: 153 W-CQY-FTP--KFRGTHVDVEVKGKRVMKLLNHIETYEMDQPRLIMRFLPAPGAYWAGKV 208
Query: 805 QFSISTSTNLKS---IIAFKAGGMFSGRSEDVDVSLVNE--KGQKLGSLKGQWTKEVRDL 859
+ T+L++ +I+ F G + + E G +L ++ G W + V
Sbjct: 209 KIK-CPETDLEAELHLISDSFIERFRGNNNRSIKGKIFESSSGNQLYNIFGHWDRTVM-- 265
Query: 860 DNGQQIWKCGPLVENSEKKYGFTVF----TSNLNEITETEKDHL--PPTDSRLRPDIRLY 913
+ K G L K T NL E+TE+E + ++ L+ D
Sbjct: 266 ---AKNIKTGELEVIYNAKENITGLKPPTVKNLEEVTESESTMVWSEVSEGILKKDWE-- 320
Query: 914 ENGIITEAEQMKLSLEQKQR----ERRDKGEDAQPQYFKQIKPMK 954
A + K+ +E+KQR +R GE P++F +K K
Sbjct: 321 ------RAREAKIVVEEKQRASLKQREASGESWVPKHFLVVKDGK 359
>YOR237w [T] KOG2210 Oxysterol-binding protein
Length = 434
Score = 58.2 bits (139), Expect = 6e-08
Identities = 76/356 (21%), Positives = 139/356 (38%), Gaps = 49/356 (13%)
Query: 636 DLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDE----------------VQR 679
DLSS+S P + P S+ + E+ L + + ++ + Q
Sbjct: 23 DLSSLSAPPFILSPTSLTEFSQYWAEHPALFLEPSLIDGENYKDHCPFDPNVESKEVAQM 82
Query: 680 LKYISAFALSYMSIHRQKTRSL---RKPFTPLLGETY------ELVREDMGIRLVSEKVC 730
L + F + S + ++ S+ +KP P LGE + + E L+SE+V
Sbjct: 83 LAVVRWFISTLRSQYCSRSESMGSEKKPLNPFLGEVFVGKWKNDEHPEFGETVLLSEQVS 142
Query: 731 HKPPIFAF--YTEHRDWKCSYTVTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQPTI 788
H PP+ AF + E D ++ + K++ T + + D Y + P +
Sbjct: 143 HHPPMTAFSIFNEKNDVSVQ-GYNQIKTGFTKTLTLTVKPYGHVILKIKDETYLITTPPL 201
Query: 789 VLKNIIAGERYMEPSNQFSISTSTNLKSIIAFKAGGMFSGRSEDVDVSLV------NEKG 842
++ I+ ++E + I +S + +I F G F+G+ + + K
Sbjct: 202 HIEGILVASPFVELGGRSFIQSSNGMLCVIEFSGRGYFTGKKNSFKARIYRSPQEHSHKE 261
Query: 843 QKLGSLKGQWTKEVRDLDNGQQIWKCGPLVENSEKKYGFTVFTSNLNEITETEKDHLPPT 902
L + GQW+ + Q+ S + Y + + + E+ H P
Sbjct: 262 NALYLISGQWSGVSTIIKKDSQV---------SHQFYDSSETPTEHLLVKPIEEQH-PLE 311
Query: 903 DSRLRPDI-RLYENGIITEAEQMKLSLEQKQR----ERRDKGEDAQPQYFKQIKPM 953
R D+ G I+ ++ K LE KQR + R KG + Q ++FKQ+ M
Sbjct: 312 SRRAWKDVAEAIRQGNISMIKKTKEELENKQRALREQERVKGVEWQRRWFKQVDYM 367
>Hs20070331 [T] KOG2210 Oxysterol-binding protein
Length = 736
Score = 58.2 bits (139), Expect = 6e-08
Identities = 62/249 (24%), Positives = 111/249 (43%), Gaps = 36/249 (14%)
Query: 633 VGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDE---VQRLK-YISAFAL 688
+G DL+ + +P + E S+L++ ++ F + L + +D + VQ +K Y+SAF
Sbjct: 384 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 443
Query: 689 SYMSIHRQKTRSLRKPFTPLLGETY--------------ELVREDM-------GIRLVSE 727
+K +KP+ P+LGE + ELV E + V+E
Sbjct: 444 G------RKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAE 497
Query: 728 KVCHKPPIFAFYTEHRDWKCSYT--VTPVQKFWGKSIEFTNEGVFELTFNNIDAKYRWSQ 785
+V H PPI AFY E + K + + KF G SI N G ++ + D Y +
Sbjct: 498 QVSHHPPISAFYAECFNKKIQFNAHIWTKSKFLGMSIGVHNIGQGCVSCLDYDEHYILTF 557
Query: 786 PTIVLKNIIAGERYMEPSNQFSISTS-TNLKSIIAFKAGGMFSGRSEDVDVSLVNEKGQK 844
P ++I+ ++E + +I+ S T + I F + G+ + + + +K
Sbjct: 558 PNGYGRSILT-VPWVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKK 616
Query: 845 -LGSLKGQW 852
S++G+W
Sbjct: 617 SFCSIEGEW 625
>7303831 [T] KOG2210 Oxysterol-binding protein
Length = 764
Score = 57.4 bits (137), Expect = 1e-07
Identities = 48/166 (28%), Positives = 79/166 (46%), Gaps = 30/166 (18%)
Query: 633 VGKDLSSISMPISLNEPVSILQVLSEAFEYSWLLSKAATMEDDEVQRLKYISAFALSYMS 692
+G DL+ + +P + E S+L++ ++ F + L K + + DD R+ + + YMS
Sbjct: 408 IGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFIKISDL-DDPRDRIVQVCRW---YMS 463
Query: 693 IHR--QKTRSLRKPFTPLLGETYELVREDMGIR--------------------LVSEKVC 730
+ +K+ +KP+ P+LGE ++ + GI ++E+V
Sbjct: 464 AYHAGRKSAVAKKPYNPILGEVFQCHWDIPGISQDAQEVRDGPVPWCRRDQLTFLAEQVS 523
Query: 731 HKPPIFAFYTEHRDWKCSYT--VTPVQKFWGKSIEFTN--EGVFEL 772
H PPI AFY EH + K ++ V KF G SI N EGV L
Sbjct: 524 HHPPISAFYAEHYNKKITFAAHVWTKSKFLGLSIGVHNIGEGVVTL 569
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.313 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,696,610
Number of Sequences: 60738
Number of extensions: 2574243
Number of successful extensions: 7633
Number of sequences better than 1.0e-05: 52
Number of HSP's better than 0.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 7415
Number of HSP's gapped (non-prelim): 87
length of query: 980
length of database: 30,389,216
effective HSP length: 116
effective length of query: 864
effective length of database: 23,343,608
effective search space: 20168877312
effective search space used: 20168877312
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)