ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4218 good E KOG0053 Amino acid transport and metabolism Cystathionine beta-lyases/cystathionine gamma-synthases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4218 1489188 1487809 -460
(460 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 555 e-158
At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 273 5e-73
CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 209 7e-54
7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 197 4e-50
YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 193 4e-49
CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 193 4e-49
HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 178 1e-44
Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 178 1e-44
At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 152 1e-36
At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 149 9e-36
CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 122 1e-27
YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 113 5e-25
At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine ga... 113 7e-25
SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine g... 112 1e-24
SPAC23A1.14c [E] KOG0053 Cystathionine beta-lyases/cystathionine... 104 2e-22
YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 98 2e-20
YHR112c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 94 6e-19
SPCC11E10.01 [E] KOG0053 Cystathionine beta-lyases/cystathionine... 81 3e-15
YLL058w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamm... 54 4e-07
>YGL184c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 465
Score = 555 bits (1429), Expect = e-158
Identities = 285/459 (62%), Positives = 353/459 (76%), Gaps = 13/459 (2%)
Query: 6 LNTSLVSV-SHNDKYGSSVPPLYQSTTFKAS-SFDQLQEYDYTRSGNPTRTVLQQQIANL 63
L+T +V+ S ND++ +SVPP+Y STTFK + + Q YDY+RSGNPTR+VLQ QI L
Sbjct: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
Query: 64 YDVAPEQVFAVSSGMTALDIILRTLI---DNSDHIPTIIAGDDLYGGTQRLLTFLQTRNH 120
Y V E V AVSSGMTALD+ILR L+ +H PTIIAGDDLYGGTQRLL F + ++H
Sbjct: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
Query: 121 AKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCK 180
A +H DT+D E F ++ SL +VD VLLESPTNPL KV D+PR+ +FVK S +
Sbjct: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKC---ISPDTT 182
Query: 181 IVVDNTMMSGLNSNPLQF--GADVVYESGTKYLNGHHDIMAGVIIAKK-DVAPSVYFVIN 237
+VVDNTMMSGLN NPLQ G DVVYES TKYLNGHHD+M GVII+K ++A +YFVIN
Sbjct: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
Query: 238 STGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVG 297
STGAGLSPMDSWLL+RGLKTL VRLY+QQ NAM+L+HWL++ CGFKPT N+ KTRFVG
Sbjct: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
Query: 298 LESHPQFELHKSFNNGPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPC 357
L S+P F+LHKSFNNGPGAVLS ETG S+ +V+SK+L+IWAVTVSFGCVNSL+SMPC
Sbjct: 303 LRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
Query: 358 KMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFEEAGLIELQQRGNDTYLL 417
KMSHASIDPELRK+R FPEDL+RLCCGIE++ DL+ DLLAA +A +IE+++ G YL
Sbjct: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGK--YLF 420
Query: 418 NKKNGHIARNNIGETYQENYNVYDQFFGQRLVSKTSHLH 456
NK N ++A N + + ++Y++F+ Q L+ K S L+
Sbjct: 421 NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELN 459
>At3g57050 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 464
Score = 273 bits (697), Expect = 5e-73
Identities = 165/398 (41%), Positives = 241/398 (60%), Gaps = 25/398 (6%)
Query: 5 SLNTSLVSVSHN-DKYGSSVPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIANL 63
S++T LV++ + D + + PLYQ+ TFK S + YDYTRSGNPTR L+ +A L
Sbjct: 86 SVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKL 145
Query: 64 YDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHAKV 123
D A ++ F +SGM AL + LI N + I +AGDD+YGG+ RLL+ + R+ V
Sbjct: 146 -DKA-DRAFCFTSGMAALSAVTH-LIKNGEEI---VAGDDVYGGSDRLLSQVVPRSGVVV 199
Query: 124 IHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVV 183
+TT + Q +V LESPTNP +++D+ ++ + +G ++V
Sbjct: 200 KRVNTTKLDEVAAAIGP--QTKLVWLESPTNPRQQISDIRKISEMAHAQGAL-----VLV 252
Query: 184 DNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVIIAKKD-VAPSVYFVINSTGAG 242
DN++MS + S PL+ GAD+V S TK++ GH D+MAGV+ K + +A VYF+ NS G+G
Sbjct: 253 DNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSG 312
Query: 243 LSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHP 302
L+P D WL +RG+KT+++R+ KQQ NA ++ +L + + + K + GL HP
Sbjct: 313 LAPFDCWLCLRGIKTMALRIEKQQENARKIAMYL--------SSHPRVKKVYYAGLPDHP 364
Query: 303 QFELHKSFNNGPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHA 362
LH S G G+V S TG +ALS+ +V + + +++ VSFG V SLISMPC MSHA
Sbjct: 365 GHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKY--FSIAVSFGSVKSLISMPCFMSHA 422
Query: 363 SIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFE 400
SI E+R+ R EDL+R+ GIEDV DL DL AF+
Sbjct: 423 SIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFK 460
>CE07648 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 209 bits (532), Expect = 7e-54
Identities = 139/383 (36%), Positives = 209/383 (54%), Gaps = 24/383 (6%)
Query: 23 VPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALD 82
VPP+ S+T+K + + + +DY+R+GNPTR VLQ+ +A L D QVF SSG+ A
Sbjct: 27 VPPISLSSTYKQDNPGEPKGHDYSRAGNPTRDVLQKNLAALEDAKHCQVF--SSGLAATS 84
Query: 83 IILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHA-KVIHTDTTDAESFIKLYNSL 141
I+ L+ DHI + DD+YGGTQR + + NH +V D TD ++ K
Sbjct: 85 AIIN-LLKYGDHI---VCSDDVYGGTQRYIRRVAVPNHGLEVDSVDLTDVQNLEKAIKP- 139
Query: 142 GQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGAD 201
+V ESP+NPL+KV D+ + Q K+ ++ +VVDNT MS P+ GAD
Sbjct: 140 -NTKMVWFESPSNPLLKVVDIAAVVQTAKK---ANPEIVVVVDNTFMSPYFQRPISLGAD 195
Query: 202 VVYESGTKYLNGHHDIMAGVIIAKKD-VAPSVYFVINSTGAGLSPMDSWLLIRGLKTLSV 260
VV S TKY+NGH D++ G +I D ++F+ + GA SP D +L+ RGLKTL +
Sbjct: 196 VVVHSITKYINGHSDVVMGAVITDNDEFQQHLFFMQLAVGAVPSPFDCFLVNRGLKTLHI 255
Query: 261 RLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFELHKSFNNGPGAVLSI 320
R+ NA+ ++ +L+ N++ + L SHPQ E+H+ G ++S
Sbjct: 256 RMRAHYENALAVAKYLE--------ANDRIESVLYPALPSHPQHEVHEKQTKGMSGMISF 307
Query: 321 E-TGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLI 379
G+L S A +++ L ++ + S G SL +P M+HAS+ E R ++LI
Sbjct: 308 YLKGELQESRAFLSA--LKVFTLAESLGGYESLAELPSIMTHASVPAETRIVLGITDNLI 365
Query: 380 RLCCGIEDVKDLQYDLLAAFEEA 402
R+ GIED+ DL DL A + A
Sbjct: 366 RISVGIEDLDDLVADLDQALKIA 388
>7302582 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 393
Score = 197 bits (500), Expect = 4e-50
Identities = 142/390 (36%), Positives = 205/390 (52%), Gaps = 29/390 (7%)
Query: 18 KYGSSVPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSG 77
K + +PP+ STTFK + + + Y+Y+RSGNPTR VL+ A L + F SSG
Sbjct: 25 KSAAVIPPISLSTTFKQDAPGEHRGYEYSRSGNPTRNVLETCFAALDNAKYGLTF--SSG 82
Query: 78 MTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHAKVIHTDTTDAE---SF 134
+ A +L T++ + DHI I GDD+YGGT RL+ + TR D T + S
Sbjct: 83 LGATTAVL-TMLSSGDHI---IMGDDVYGGTNRLIRQVATRLGISATFVDPTKLDLIKSS 138
Query: 135 IKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSN 194
IK + +V +ESPTNPL+KVAD+ + Q V G + + VDNT ++
Sbjct: 139 IK-----PETKLVWIESPTNPLVKVADIEAIAQLVH---GVREDIVLAVDNTFLTSYFQR 190
Query: 195 PLQFGADVVYESGTKYLNGHHDI-MAGVIIAKKDVAPSVYFVINSTGAGLSPMDSWLLIR 253
PL+ GAD+V S TKY+NGH D+ M G+ + + + S+ F+ N+ G SP D + + R
Sbjct: 191 PLELGADLVCYSLTKYMNGHTDVVMGGITMNSEKLYKSLKFLQNAVGIVPSPFDCYQVNR 250
Query: 254 GLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFELHKSFNNG 313
LKTLS+R+ + Q NA+ ++ +L+ N K L SHPQ ++ G
Sbjct: 251 SLKTLSLRMEQHQKNALKVAKYLET--------NPFVEKVLHPSLPSHPQHKIALKQAYG 302
Query: 314 PGAVLSIET-GDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQR 372
V S G+L S A + K L ++ + S G SL +P M+HAS+ E RK
Sbjct: 303 YSGVFSFYIKGELKHSSAFL--KALKVFTLAESLGGYESLAELPSIMTHASVPAEDRKTL 360
Query: 373 AFPEDLIRLCCGIEDVKDLQYDLLAAFEEA 402
+ L+RL G+ED DL DL A E A
Sbjct: 361 GITDGLVRLSVGLEDADDLIKDLEQALEIA 390
>YAL012w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 394
Score = 193 bits (491), Expect = 4e-49
Identities = 137/399 (34%), Positives = 207/399 (51%), Gaps = 36/399 (9%)
Query: 15 HNDKYGSSVPPLYQSTTFKASS-FDQLQEYDYTRSGNPTRTVLQQQIANLYDVAPEQVFA 73
H D +GS + P+ STTFK SS + + Y+Y+RS NP R L++ +A L + + A
Sbjct: 19 HVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVAALENA--QYGLA 76
Query: 74 VSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHAKVIHTDTTDAES 133
SSG IL++L S H +I D+YGGT R T KV + +
Sbjct: 77 FSSGSATTATILQSLPQGS-HAVSI---GDVYGGTHRYFT--------KVANAHGVETSF 124
Query: 134 FIKLYNSLGQV-----DIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMM 188
L N L Q+ +V +E+PTNP +KV D+ ++ +K K + + +VVDNT +
Sbjct: 125 TNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIK-KHAAGQDVILVVDNTFL 183
Query: 189 SGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVIIA-KKDVAPSVYFVINSTGAGLSPMD 247
S SNPL FGAD+V S TKY+NGH D++ GV+ K + + F+ N+ GA SP D
Sbjct: 184 SPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFD 243
Query: 248 SWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFEL- 306
+WL RGLKTL +R+ + ++A I F D + + GL++HP +++
Sbjct: 244 AWLTHRGLKTLHLRVRQAALSA-------NKIAEFLAADKENVVAVNYPGLKTHPNYDVV 296
Query: 307 ---HKSFNNGPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHAS 363
H+ G I+ G A S+ +S RL + + S G + SL+ +P M+H
Sbjct: 297 LKQHRDALGGGMISFRIKGGAEAASK-FASSTRL--FTLAESLGGIESLLEVPAVMTHGG 353
Query: 364 IDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFEEA 402
I E R+ +DL+R+ GIED DL D+ A ++A
Sbjct: 354 IPKEAREASGVFDDLVRISVGIEDTDDLLEDIKQALKQA 392
>CE15884 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 392
Score = 193 bits (491), Expect = 4e-49
Identities = 131/383 (34%), Positives = 200/383 (52%), Gaps = 24/383 (6%)
Query: 23 VPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALD 82
VPP+ STT+K + + + YDY R GNPTR VLQ+ +A L Q F SSG+ A
Sbjct: 27 VPPISMSTTYKQDNPGEPKRYDYARGGNPTRDVLQKNLAALEGAKHCQAF--SSGLAASS 84
Query: 83 IILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHA-KVIHTDTTDAESFIKLYNSL 141
++ L+++ DHI + DD+YGGT R + + + + +V D TD ++ K
Sbjct: 85 AVIN-LLNHGDHI---VCSDDVYGGTIRYIRQIAVKKYGMEVDSVDLTDVQNLEKAIKP- 139
Query: 142 GQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGAD 201
+V ESP+NPL+KV D+ + Q K+ ++ +VVDNT M+ PL GAD
Sbjct: 140 -NTKMVWFESPSNPLLKVVDIAAVVQTAKR---ANPEIVVVVDNTFMTPYFQRPLSLGAD 195
Query: 202 VVYESGTKYLNGHHDIMAGVIIAKKD-VAPSVYFVINSTGAGLSPMDSWLLIRGLKTLSV 260
+ S TKY+NGH DI+ G I D ++F+ + G SP D +L+ RGLKTL V
Sbjct: 196 IAVHSITKYINGHSDIIMGAAITNNDEFQQHLHFMQRAIGGVPSPFDCFLVNRGLKTLHV 255
Query: 261 RLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFELHKSFNNGPGAVLSI 320
R+ NA+ ++ +L+ ++ + L SHPQ +H G ++S
Sbjct: 256 RMKAHFENALAIAKFLE--------AHDCIESVLYPALPSHPQHTVHVKQTKGMSGMISF 307
Query: 321 E-TGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLI 379
G+L S A +++ L ++ + S G SL +P M+HAS+ R + ++LI
Sbjct: 308 YLKGELCQSRAFLSA--LKVFTLAESLGGCESLAELPSIMTHASVPSATRAELGITDNLI 365
Query: 380 RLCCGIEDVKDLQYDLLAAFEEA 402
R+ GIED+ DL DL A + A
Sbjct: 366 RISVGIEDLDDLIADLDQALKIA 388
>HsM4503125 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 178 bits (452), Expect = 1e-44
Identities = 136/384 (35%), Positives = 194/384 (50%), Gaps = 28/384 (7%)
Query: 23 VPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALD 82
VPP+ STTFK + Q ++Y+RSGNPTR L++ +A L + A +SG+ A
Sbjct: 38 VPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGA--KYCLAFASGLAAT- 94
Query: 83 IILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHAKVIHTDTTDAESFIKLYNSL- 141
+ + L+ D I I DD+YGGT R + + K+ D S IKL +
Sbjct: 95 VTITHLLKAGDQI---ICMDDVYGGTNRYFRQVASEFGLKISFVDC----SKIKLLEAAI 147
Query: 142 -GQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGA 200
+ +V +E+PTNP KV D+ V + G + +VVDNT MS PL GA
Sbjct: 148 TPETKLVWIETPTNPTQKVIDIEGCAHIVHKHG----DIILVVDNTFMSPYFQRPLALGA 203
Query: 201 DVVYESGTKYLNGHHDIMAGVI-IAKKDVAPSVYFVINSTGAGLSPMDSWLLIRGLKTLS 259
D+ S TKY+NGH D++ G++ + + + + F+ NS GA SP+D +L RGLKTL
Sbjct: 204 DISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLH 263
Query: 260 VRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFELHKSFNNG-PGAVL 318
VR+ K N M ++ +L+ N K + GL SHPQ EL K G G V
Sbjct: 264 VRMEKHFKNGMAVAQFLE--------SNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVT 315
Query: 319 SIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDL 378
G L +E + K L ++ + S G SL +P M+HAS+ R + L
Sbjct: 316 FYIKGTLQHAEIFL--KNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTL 373
Query: 379 IRLCCGIEDVKDLQYDLLAAFEEA 402
IRL G+ED +DL DL A + A
Sbjct: 374 IRLSVGLEDEEDLLEDLDQALKAA 397
>Hs21361334 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 405
Score = 178 bits (452), Expect = 1e-44
Identities = 136/384 (35%), Positives = 194/384 (50%), Gaps = 28/384 (7%)
Query: 23 VPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALD 82
VPP+ STTFK + Q ++Y+RSGNPTR L++ +A L + A +SG+ A
Sbjct: 38 VPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGA--KYCLAFASGLAAT- 94
Query: 83 IILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHAKVIHTDTTDAESFIKLYNSL- 141
+ + L+ D I I DD+YGGT R + + K+ D S IKL +
Sbjct: 95 VTITHLLKAGDQI---ICMDDVYGGTNRYFRQVASEFGLKISFVDC----SKIKLLEAAI 147
Query: 142 -GQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGA 200
+ +V +E+PTNP KV D+ V + G + +VVDNT MS PL GA
Sbjct: 148 TPETKLVWIETPTNPTQKVIDIEGCAHIVHKHG----DIILVVDNTFMSPYFQRPLALGA 203
Query: 201 DVVYESGTKYLNGHHDIMAGVI-IAKKDVAPSVYFVINSTGAGLSPMDSWLLIRGLKTLS 259
D+ S TKY+NGH D++ G++ + + + + F+ NS GA SP+D +L RGLKTL
Sbjct: 204 DISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLH 263
Query: 260 VRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFELHKSFNNG-PGAVL 318
VR+ K N M ++ +L+ N K + GL SHPQ EL K G G V
Sbjct: 264 VRMEKHFKNGMAVAQFLE--------SNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVT 315
Query: 319 SIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDL 378
G L +E + K L ++ + S G SL +P M+HAS+ R + L
Sbjct: 316 FYIKGTLQHAEIFL--KNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTL 373
Query: 379 IRLCCGIEDVKDLQYDLLAAFEEA 402
IRL G+ED +DL DL A + A
Sbjct: 374 IRLSVGLEDEEDLLEDLDQALKAA 397
>At3g01120 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 563
Score = 152 bits (384), Expect = 1e-36
Identities = 107/359 (29%), Positives = 173/359 (47%), Gaps = 22/359 (6%)
Query: 43 YDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGD 102
++Y R GNPT VL+ +I+ L E ++SGM A ++L L+ HI T
Sbjct: 224 FEYGRYGNPTTVVLEDKISALEGA--ESTLVMASGMCASTVMLLALVPAGGHIVTTT--- 278
Query: 103 DLYGGTQRLLTFLQTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADL 162
D Y T+ + + V D D N +V + ESPTNP ++ D+
Sbjct: 279 DCYRKTRIFMENFLPKLGITVTVIDPADIAGLEAAVNEF-KVSLFFTESPTNPFLRCVDI 337
Query: 163 PRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVI 222
+ + ++G + +D T + LN L GAD+V S TKY+ GH+D++AG I
Sbjct: 338 ELVSKICHKRG-----TLVCIDGTFATPLNQKALALGADLVVHSATKYIGGHNDVLAGCI 392
Query: 223 IAKKDVAPSVYFVINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGF 282
+ + + + G L+P ++L+IRG+KTL +R+ +Q A ++ L+
Sbjct: 393 CGSLKLVSEIRNLHHVLGGTLNPNAAYLIIRGMKTLHLRVQQQNSTAFRMAEILE----- 447
Query: 283 KPTDNNQQLKTRFVGLESHPQFELHKSFNNGPGAVLSIE-TGDLALSEAIVTSKRLNIWA 341
+ + + GL SHP+ EL K G G V+S E GD+ + V S L I
Sbjct: 448 ---AHPKVSHVYYPGLPSHPEHELAKRQMTGFGGVVSFEIDGDIETTIKFVDS--LKIPY 502
Query: 342 VTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFE 400
+ SFG S++ P MS+ + E R + ++L+R G+ED +D++ D+L A E
Sbjct: 503 IAPSFGGCESIVDQPAIMSYWDLPQEERLKYGIKDNLVRFSFGVEDFEDVKADILQALE 561
>At1g33320 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 412
Score = 149 bits (376), Expect = 9e-36
Identities = 105/359 (29%), Positives = 179/359 (49%), Gaps = 23/359 (6%)
Query: 43 YDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGD 102
Y+Y R GNPT L+++I+ L E ++SGM A +++L L+ + HI +A
Sbjct: 74 YEYARYGNPTTMALEEKISVLEGA--ESTLVMASGMYASNVMLLALVPTNGHI---VATK 128
Query: 103 DLYGGTQRLLTFLQTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADL 162
D Y T+ + T+ V D+ D L N+ +V + ESPTNP ++ D+
Sbjct: 129 DCYKETRIFMENFLTKLGITVTFIDSDDIAGLQTLVNN-HEVSLFFTESPTNPFLRCVDI 187
Query: 163 PRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVI 222
+ + ++G + +D T+ + +N L GAD+V+ S TKY+ GH+D +AG I
Sbjct: 188 KLVSKICHRRG-----TLVCIDATIATPINQKTLALGADLVHHSATKYIGGHNDFLAGSI 242
Query: 223 IAKKDVAPSVYFVINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGF 282
++ + + G L+P ++LLIRG+KT+ +R+ +Q M ++ L+
Sbjct: 243 SGSMELVSKIRNLHKLLGGTLNPNAAYLLIRGMKTMHLRVRQQNSTGMKMAQVLE----- 297
Query: 283 KPTDNNQQLKTRFVGLESHPQFELHKSFNNGPGAVLSIE-TGDLALSEAIVTSKRLNIWA 341
+ + + ++GL SHP+ + K G G ++S E GDL + + + L I
Sbjct: 298 ---AHPKVSRVYYLGLPSHPEHLIAKRQMTGIGGLISFEIDGDLKTTIKFIDA--LKIPY 352
Query: 342 VTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFE 400
+ SFG SL+ I E R + F ++L+R GIED +D++ D+L A E
Sbjct: 353 LAASFGGCESLVDQ-LATGIWDIPREERLKDGFQDNLVRFSFGIEDFEDIKADVLQALE 410
>CE17400 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 122 bits (305), Expect = 1e-27
Identities = 107/407 (26%), Positives = 178/407 (43%), Gaps = 43/407 (10%)
Query: 9 SLVSVSHNDKYGSSVP---PLYQSTTFKASSFDQLQE------YDYTRSGNPTRTVLQQQ 59
S +S SH ++ P P+Y S+T++ + DQ E + Y R GNPT ++
Sbjct: 66 SRISTSHAKPLSNADPVVVPIYHSSTYRFKTVDQFNEDNHGANFVYRRCGNPTTENVEVV 125
Query: 60 IANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRN 119
I + A ++ +SG+ A+ + + + H+ I + +Y GT + R
Sbjct: 126 INEIEGGAGSLLY--NSGLAAISAVFLEFLSSGAHM---IVMNPIYSGTSSFINETLARF 180
Query: 120 HAKVIHTDTTDAESFIKLYNSL--GQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSS 177
++ D + F ++ ES NP M V D+ + K+
Sbjct: 181 GVEITSVDVEKEKDFAGAVEKAIRPNTKMIYFESIANPTMAVPDILGTIEVAKKY----- 235
Query: 178 NCKIV--VDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVI-IAKKDVAPSVYF 234
KI+ +D T S N PL+ GAD+ S +KY+ GH D++AGV+ ++ D +
Sbjct: 236 --KILTCLDATFSSPYNIQPLKLGADISLHSCSKYIGGHTDVIAGVVTVSSYDNWKKLKL 293
Query: 235 VINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTR 294
+TG+ LSP D+ LL RGLKTL +R+ + NA + +L+ + + +
Sbjct: 294 QQLTTGSSLSPYDAALLTRGLKTLGLRVDRISENAQKTAEFLE--------SHPKVERVF 345
Query: 295 FVGLESHPQFELHKSFNNGPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLIS 354
+ GL SHPQ + K +++ + G + +V + +S G SLI
Sbjct: 346 YPGLPSHPQHQYAKQVMKQFAGMIAFDVGTAENAIKLVEA---------ISLGGTESLIE 396
Query: 355 MPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFEE 401
P MSH L+R GIE+V+D+ DL A E+
Sbjct: 397 HPLSMSHGKHLLRYLDGPTVAPGLLRFSVGIENVEDIIGDLNDALEK 443
>YLR303w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 444
Score = 113 bits (283), Expect = 5e-25
Identities = 115/441 (26%), Positives = 195/441 (44%), Gaps = 79/441 (17%)
Query: 16 NDKYGSSVPPLYQSTTFKASSFD--------QLQEYDYTRSGNPTRTVLQQQIANLYDVA 67
++ + S P+Y +T++ + ++ Y Y+R NPT VL+++IA L A
Sbjct: 19 DNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTSNVLEERIAALEGGA 78
Query: 68 PEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGT--QRLLTFLQTRNHAKVIH 125
AVSSG A + ++ L D+I ++ LYGGT Q ++F + A+ +
Sbjct: 79 A--ALAVSSGQAAQTLAIQGLAHTGDNI---VSTSYLYGGTYNQFKISFKRFGIEARFVE 133
Query: 126 TDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDN 185
D + E F K+++ + V LE+ NP V D ++ + G +VVDN
Sbjct: 134 GD--NPEEFEKVFDE--RTKAVYLETIGNPKYNVPDFEKIVAIAHKHG-----IPVVVDN 184
Query: 186 TM-MSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVII--------------------- 223
T G P+++GAD+V S TK++ GH + G+I+
Sbjct: 185 TFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKDYPEKFPQFSQPA 244
Query: 224 ----------AKKDVAPSVYF---VINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAM 270
A ++A V+ ++ G ++P S+LL++G++TLS+R + NA+
Sbjct: 245 EGYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFASFLLLQGVETLSLRAERHGENAL 304
Query: 271 VLSHWLQDICGFKPTDNNQQLKTRFVGLESHPQFELHKSF-NNGPGAVLSI--------- 320
L+ WL+ + + GL SH E K + +NG G VLS
Sbjct: 305 KLAKWLE--------QSPYVSWVSYPGLASHSHHENAKKYLSNGFGGVLSFGVKDLPNAD 356
Query: 321 -ETGDLALSEAIVTSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLI 379
ET LS A V L + + + G +L+ P +H ++ + + +DLI
Sbjct: 357 KETDPFKLSGAQVVD-NLKLASNLANVGDAKTLVIAPYFTTHKQLNDKEKLASGVTKDLI 415
Query: 380 RLCCGIEDVKDLQYDLLAAFE 400
R+ GIE + D+ D +FE
Sbjct: 416 RVSVGIEFIDDIIADFQQSFE 436
>At1g64660 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 441
Score = 113 bits (282), Expect = 7e-25
Identities = 96/352 (27%), Positives = 162/352 (45%), Gaps = 32/352 (9%)
Query: 43 YDYTRSGNPTRTVLQQQIANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGD 102
Y Y+R NPT L +Q+A L + + SSGM+A+ ++ L + H+ +A
Sbjct: 93 YVYSRHFNPTVLNLSRQMAALEGT--QAAYCTSSGMSAISSVMLQLCSSGGHV---VAAS 147
Query: 103 DLYGGTQRLLT-FLQTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVAD 161
LYGGT LL+ FL + D TD + G+ ++ ES NP + VAD
Sbjct: 148 TLYGGTHALLSHFLPRTCNITTSFVDITDHGAVANAIVE-GRTQVLYFESVANPTLTVAD 206
Query: 162 LPRLCQFVKQKGGSSSNCKIVVDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGV 221
+P L + +KG + +VVDNT + S P + GADVV S +K+++G DI+AG
Sbjct: 207 IPELSRMAHEKGVT-----VVVDNTFAPMVLS-PAKLGADVVVHSISKFISGGADIIAGA 260
Query: 222 IIAKKDVAPSVYFVINST----GAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQ 277
+ +++ + + + G ++ ++ L + L +R+ + A V + ++
Sbjct: 261 VCGSENLVKEMMDLRGGSLMLLGPTMNAKVAFELSERIPHLGLRMREHSHRAQVYAERMR 320
Query: 278 DICGFKPTDNNQQLKTRFVGLESHPQFELHKSFNN---GPGAVLSI--ETGDLALSEAIV 332
D+ +K + GLE+HPQ +L K N G G +LSI ET + A
Sbjct: 321 DL----------GMKVIYPGLETHPQHKLFKGMVNRDYGYGGLLSIDMETEEKANKLMAY 370
Query: 333 TSKRLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLIRLCCG 384
+ VS G +L+S + + +DP ++ L+R+ G
Sbjct: 371 LQNATQFGFMAVSLGYYETLMSCSGSSTSSELDPSQKEAAGISPGLVRMSVG 422
>SPBC428.11 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 429
Score = 112 bits (280), Expect = 1e-24
Identities = 119/427 (27%), Positives = 176/427 (40%), Gaps = 67/427 (15%)
Query: 21 SSVPPLYQSTTFKASSFDQ------LQE--YDYTRSGNPTRTVLQQQIANLYDVAPEQVF 72
S P+Y +T++ D LQE Y Y+R NPT V +++IA L A
Sbjct: 25 SRAVPIYATTSYVFRDCDHGGRLFGLQEPGYIYSRMMNPTADVFEKRIAALEHGAA--AI 82
Query: 73 AVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFLQTRNHAKVIHTDTTDAE 132
A SSG +AL + L TL D+I ++ LYGGT L R + D
Sbjct: 83 ATSSGTSALFMALTTLAKAGDNI---VSTSYLYGGTYNLFKVTLPRLGITTKFVNGDDPN 139
Query: 133 SFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNTMMSG-L 191
+ V +ES NP+ V D R+ + G ++VDNT G
Sbjct: 140 DLAAQIDE--NTKAVYVESIGNPMYNVPDFERIAEVAHAAG-----VPLMVDNTFGGGGY 192
Query: 192 NSNPLQFGADVVYESGTKYLNGHHDIMAGVIIA------KKDVAPSVYF----------- 234
P+ GAD+V S TK++ GH + GVI+ KK+ F
Sbjct: 193 LVRPIDHGADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPHPGYHGMV 252
Query: 235 -----------------VINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQ 277
+ G +P +LL++GL+TLS+R+ + NA L+ +L+
Sbjct: 253 FTETFGNLAYAFACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAFALAKYLE 312
Query: 278 DICGFKPTDNNQQLKTRFVGLESHPQFELHKSF-NNGPGAVLSI-ETGDLALSEAIVTSK 335
P N + GLESH +L K + NG GAVLS G S +V +
Sbjct: 313 K----HPKVN----WVSYPGLESHVSHKLAKKYLKNGYGAVLSFGAKGGPDQSRKVVNA- 363
Query: 336 RLNIWAVTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDL 395
L + + + G +L+ P +H + E + +DLIR+ GIE + D+ D
Sbjct: 364 -LKLASQLANVGDAKTLVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDIIADF 422
Query: 396 LAAFEEA 402
A E A
Sbjct: 423 AQALEVA 429
>SPAC23A1.14c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 398
Score = 104 bits (260), Expect = 2e-22
Identities = 113/418 (27%), Positives = 181/418 (43%), Gaps = 57/418 (13%)
Query: 3 KPSLNTSLVSVSHNDKYGSS---VPPLYQSTTFK-------ASSFDQLQEYDYTRSGNPT 52
K +L+T+++ +D Y PP++ STT+ F +L E D+ +
Sbjct: 13 KSTLSTNVLHA--DDAYALENDVAPPIHISTTYTYPGTPDTLQPFTKLAEEDFPYYARIS 70
Query: 53 RTVLQQQIANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLL 112
+ + A+L V SSG+ A+ +L L N HI G Y GT +++
Sbjct: 71 GNNVDRAEASLSSVLGAPSVVYSSGLAAIYGLLSYL--NPKHIAVHKPGFGGYSGTIQII 128
Query: 113 TFLQTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQK 172
+ N + T D + +++G+ D++ LE+P NPL D+P + K+K
Sbjct: 129 ARI---NRLTGLETSFIDGKC-----DAIGEGDVIWLETPLNPLGIAFDIPFYKELAKKK 180
Query: 173 GGSSSNCKIVVDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVIIAKKDVAPSV 232
G +VVD+T + L GAD V S TKYL GH D++AGV A KD + +
Sbjct: 181 GAI-----LVVDSTFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGV-TASKDRSKIL 234
Query: 233 YFVINST--GAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQ 290
+ G L P ++LL+R L+T +R+ K N +++ L + ++Q
Sbjct: 235 DLKADRAYLGTILHPQQAFLLLRSLRTFPLRIAKHSENGFLVAQHLNKLA------TDEQ 288
Query: 291 LKTRFVGLESHPQFEL-HKSFNNGPGAVLSIETGDLALSEAIVTSK--------RLNIWA 341
T +G++S E+ H S ++ G + ++ S L +
Sbjct: 289 FATS-LGIDSSLILEVYHNSLQTKEFVAKNLTGGHASCFSVLLKSDTVAKHLCCELKYFH 347
Query: 342 VTVSFGCVNSLISMPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAF 399
S G V SLI +M+ + IDP L+RL GIED DL DL F
Sbjct: 348 HATSLGSVESLIEWR-RMTDSKIDPR----------LVRLSIGIEDAADLIADLNRVF 394
>YFR055w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 340
Score = 98.2 bits (243), Expect = 2e-20
Identities = 79/281 (28%), Positives = 133/281 (47%), Gaps = 17/281 (6%)
Query: 1 MSKPSLNTSLVSVSHN--DKYGSSVPPLYQSTTF---KASSFDQLQEYDYTRSGNPTRTV 55
+SK + T L + N ++ G PPLY+ +T K S +Q + Y +G+PT
Sbjct: 7 LSKFGITTQLSVIGRNPDEQSGFVNPPLYKGSTIILKKLSDLEQRKGRFYGTAGSPTIDN 66
Query: 56 LQQQIANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLLTFL 115
L+ +L A + A SG+ ++ + L L DHI + D +Y T+ L L
Sbjct: 67 LENAWTHLTGGAGTVLSA--SGLGSISLALLALSKAGDHI---LMTDSVYVPTRMLCDGL 121
Query: 116 QTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGS 175
+ + + D + + KL ++ LESP + M+V D+P L K+ G
Sbjct: 122 LAKFGVETDYYDPSIGKDIEKLVKP--NTTVIFLESPGSGTMEVQDIPALVSVAKKHG-- 177
Query: 176 SSNCKIVVDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVIIAKKDVAPSVYFV 235
K ++DNT + L + G D+ E+GTKYL GH D++ G+ A ++ P +
Sbjct: 178 ---IKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEECWPLLRST 234
Query: 236 INSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWL 276
++ D L +RG++TL +RL + + A+ L+ WL
Sbjct: 235 YDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDLAAWL 275
>YHR112c [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 378
Score = 93.6 bits (231), Expect = 6e-19
Identities = 108/415 (26%), Positives = 172/415 (41%), Gaps = 64/415 (15%)
Query: 6 LNTSLVSVSHNDKYGSSV-PPLYQSTTFKASSFDQLQEYD------------YTRSGNPT 52
L+T+L+ D + V PP+ STTF+ D + + Y+R +P
Sbjct: 4 LSTALIHGDDKDNRVTDVAPPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRLAHPN 63
Query: 53 RTVLQQQIANLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDDLYGGTQRLL 112
T L+ + + D SSG+ A + + P I Y G + +
Sbjct: 64 STRLESIFSEILD---GYAVIYSSGLAAFYAAM------VHYNPKKIFIGQSYHGVRAIA 114
Query: 113 TFLQTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQK 172
L TRN+ H D E + DIV LESP NP +D+ L + K
Sbjct: 115 NIL-TRNYGIEQHP-LEDIEK------CASEGDIVHLESPVNPYGTSSDIESLARRAHAK 166
Query: 173 GGSSSNCKIVVDNTMMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVIIAKKDVA--- 229
G ++VD+T S FGAD+V S TKY GH D+++GV++ K++
Sbjct: 167 GAL-----LIVDSTFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQ 221
Query: 230 ---PSVYFVINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTD 286
+Y G ++ ++S++L+R L+T +R+ KQ NA L +L D ++
Sbjct: 222 LKDDRIYL-----GTNVANLESFMLLRSLRTYEMRITKQSENATKLVRFLSD----HQSE 272
Query: 287 NNQQLKTRFVGLESHPQFELHKSFNNGPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSF 346
++ LKT + +F + K G G V +I + +L + S
Sbjct: 273 FDKVLKTIYHSSLQTEEF-VKKQLVGGYGPVFAITL--YTKEQCKQLPLKLKYFHHATSL 329
Query: 347 GCVNSLISMPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFEE 401
G + SL+ A DP + + LIR+ G E DL DL +A +E
Sbjct: 330 GGIESLVEW-----RAMTDPYI------DQTLIRVSVGCESANDLIKDLASALKE 373
>SPCC11E10.01 [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 101
Score = 81.3 bits (199), Expect = 3e-15
Identities = 47/102 (46%), Positives = 65/102 (63%), Gaps = 7/102 (6%)
Query: 3 KPSLNTSLVSVSHN-DKYGSSVPPLYQSTTFKASSFDQLQEYDYTRSGNPTRTVLQQQIA 61
K S++T LV V N D+Y +S P+YQS TFK + + ++DYTRSGNPTR+VLQ +A
Sbjct: 6 KYSVDTELVHVEGNEDQYHASSVPIYQSATFKQPCLEHMGKFDYTRSGNPTRSVLQVHLA 65
Query: 62 NLYDVAPEQVFAVSSGMTALDIILRTLIDNSDHIPTIIAGDD 103
L + + F S+GM+ALD+ILR NS ++AG D
Sbjct: 66 KL--MKAKHAFVTSNGMSALDMILRCCKSNSH----VVAGHD 101
>YLL058w [E] KOG0053 Cystathionine beta-lyases/cystathionine gamma-synthases
Length = 575
Score = 54.3 bits (129), Expect = 4e-07
Identities = 71/273 (26%), Positives = 121/273 (44%), Gaps = 31/273 (11%)
Query: 127 DTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGSSSNCKIVVDNT 186
D + + F++ S ++ V +E+P+NPL+ + DL +L Q G IV+D+T
Sbjct: 303 DVVELQKFLE--TSKQRILAVFVETPSNPLLNMPDLKKLRSLADQYG-----FFIVIDDT 355
Query: 187 MMSGLNSNPLQFGADVVYESGTKYLNGHHDIMAGVII--AKKDVAPSV--YFVINSTGAG 242
+ GLN + L + AD+V S TK NG ++M G ++ K + P YF +
Sbjct: 356 -IGGLNVDILPY-ADIVSTSLTKLFNGASNVMGGSVVLNPKSSLYPYAREYFRSANFEDL 413
Query: 243 LSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLKTRFVGLESHP 302
L D+ +L R + R + N +L L D+ P + K + + S
Sbjct: 414 LWCEDAIVLERNSRDFEDRTLRANANTGIL---LNDL--LLPEEGKICKKIYYPTVTSKE 468
Query: 303 QFELHKSFNN---GPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSL-ISMPCK 358
FE ++S N G G + S+ + ++A S + V G N ++ C
Sbjct: 469 TFENYESVRNERGGYGCLFSVAFFNEGDAKAFYDS-------LKVFKGPSNGTNFTLACP 521
Query: 359 MSHASIDPELRKQRAFPED--LIRLCCGIEDVK 389
H + EL + F D +IR+ G+ED++
Sbjct: 522 YVHLAHHSELEEVSKFGADPNIIRVSVGLEDIQ 554
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.134 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,004,175
Number of Sequences: 60738
Number of extensions: 1203046
Number of successful extensions: 2673
Number of sequences better than 1.0e-05: 19
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2580
Number of HSP's gapped (non-prelim): 22
length of query: 460
length of database: 30,389,216
effective HSP length: 110
effective length of query: 350
effective length of database: 23,708,036
effective search space: 8297812600
effective search space used: 8297812600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)