ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4250 check: MH OUT KOG0595 Intracellular trafficking, secretion, and vesicular transport Serine/threonine-protein kinase involved in autophagy
r_klactIII4250 check: MH OUT KOG0595 Posttranslational modification, protein turnover, chaperones Serine/threonine-protein kinase involved in autophagy
r_klactIII4250 check: MH OUT KOG0595 Signal transduction mechanisms Serine/threonine-protein kinase involved in autophagy
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4250 1498959 1501451 831
(831 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved i... 753 0.0
SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involve... 282 1e-75
At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved... 185 2e-46
At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved... 181 4e-45
CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 179 2e-44
Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved... 167 6e-41
Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved... 167 8e-41
7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 164 4e-40
7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 161 3e-39
7294217 [D] KOG0588 Serine/threonine protein kinase 144 4e-34
CE00847 [T] KOG0583 Serine/threonine protein kinase 141 4e-33
CE28218 [D] KOG0588 Serine/threonine protein kinase 139 1e-32
At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved... 139 1e-32
Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involve... 138 3e-32
Hs20545245 [D] KOG0588 Serine/threonine protein kinase 135 3e-31
At1g29230 [T] KOG0583 Serine/threonine protein kinase 135 3e-31
Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED 134 6e-31
At5g58380 [T] KOG0583 Serine/threonine protein kinase 134 8e-31
At5g39440 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
At5g45820 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
At5g07070 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
At3g01090 [T] KOG0583 Serine/threonine protein kinase 132 2e-30
YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 131 4e-30
At3g29160 [T] KOG0583 Serine/threonine protein kinase 131 5e-30
YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 130 8e-30
At2g34180 [T] KOG0583 Serine/threonine protein kinase 130 1e-29
Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 129 1e-29
7293496 [R] KOG0597 Serine-threonine protein kinase FUSED 129 1e-29
At5g01810 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
At5g01820 [T] KOG0583 Serine/threonine protein kinase 129 2e-29
At5g25110 [T] KOG0583 Serine/threonine protein kinase 128 4e-29
At5g10930 [T] KOG0583 Serine/threonine protein kinase 128 4e-29
At1g30270 [T] KOG0583 Serine/threonine protein kinase 128 4e-29
At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED 127 5e-29
YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 127 7e-29
SPCC74.03c [T] KOG0583 Serine/threonine protein kinase 127 7e-29
7299437 [R] KOG0586 Serine/threonine protein kinase 127 9e-29
YDR477w [T] KOG0583 Serine/threonine protein kinase 126 1e-28
CE28643 [T] KOG0583 Serine/threonine protein kinase 126 1e-28
CE07458 [T] KOG0583 Serine/threonine protein kinase 126 1e-28
Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase 126 2e-28
Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 126 2e-28
7303211 [T] KOG4717 Serine/threonine protein kinase 125 2e-28
Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 125 2e-28
SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinas... 125 3e-28
At4g18700 [T] KOG0583 Serine/threonine protein kinase 125 3e-28
Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 125 3e-28
Hs21361643 [T] KOG4717 Serine/threonine protein kinase 124 5e-28
7302570 [R] KOG0586 Serine/threonine protein kinase 124 5e-28
Hs5453964 [T] KOG0583 Serine/threonine protein kinase 124 8e-28
Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 124 8e-28
YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase 123 1e-27
Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 123 1e-27
7290150 [T] KOG0583 Serine/threonine protein kinase 123 1e-27
SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase 122 2e-27
Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neuro... 122 2e-27
At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involv... 122 2e-27
Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specif... 122 3e-27
Hs14770402 [R] KOG0586 Serine/threonine protein kinase 122 3e-27
SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 121 4e-27
Hs13899225 [R] KOG0586 Serine/threonine protein kinase 121 4e-27
CE27768 [R] KOG0586 Serine/threonine protein kinase 121 4e-27
CE05274 [T] KOG0690 Serine/threonine protein kinase 121 4e-27
HsM4505103 [R] KOG0586 Serine/threonine protein kinase 121 5e-27
Hs8923922 [R] KOG0586 Serine/threonine protein kinase 120 7e-27
CE23838 [R] KOG0586 Serine/threonine protein kinase 120 7e-27
7302464 [R] KOG0586 Serine/threonine protein kinase 120 7e-27
YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 120 9e-27
Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase 120 9e-27
7290249 [R] KOG0586 Serine/threonine protein kinase 120 9e-27
YAR018c [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 120 1e-26
7301734 [T] KOG0694 Serine/threonine protein kinase 120 1e-26
Hs21361133 [R] KOG0586 Serine/threonine protein kinase 119 1e-26
CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 119 1e-26
7299438 [R] KOG0586 Serine/threonine protein kinase 119 1e-26
YCL024w [T] KOG0583 Serine/threonine protein kinase 119 2e-26
Hs5453966 [T] KOG0583 Serine/threonine protein kinase 119 2e-26
At5g45810 [T] KOG0583 Serine/threonine protein kinase 119 2e-26
Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 118 3e-26
Hs9845489 [R] KOG0586 Serine/threonine protein kinase 118 3e-26
Hs9845487 [R] KOG0586 Serine/threonine protein kinase 118 3e-26
Hs22062450 [R] KOG0586 Serine/threonine protein kinase 118 3e-26
At4g24400 [T] KOG0583 Serine/threonine protein kinase 118 3e-26
At2g25090 [T] KOG0583 Serine/threonine protein kinase 118 3e-26
Hs4507275 [D] KOG0580 Serine/threonine protein kinase 118 4e-26
At2g30360 [T] KOG0583 Serine/threonine protein kinase 118 4e-26
CE15235 [R] KOG0589 Serine/threonine protein kinase 117 6e-26
At3g23000 [T] KOG0583 Serine/threonine protein kinase 117 6e-26
At2g38490 [T] KOG0583 Serine/threonine protein kinase 117 6e-26
7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 117 6e-26
YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 117 7e-26
At4g30960 [T] KOG0583 Serine/threonine protein kinase 117 7e-26
At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 117 7e-26
Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 117 9e-26
YDR507c [D] KOG0588 Serine/threonine protein kinase 116 1e-25
HsM8923212 [T] KOG4717 Serine/threonine protein kinase 116 2e-25
Hs5453976 [T] KOG0694 Serine/threonine protein kinase 116 2e-25
YPL209c [D] KOG0580 Serine/threonine protein kinase 115 2e-25
At4g14580 [T] KOG0583 Serine/threonine protein kinase 115 2e-25
At2g26980 [T] KOG0583 Serine/threonine protein kinase 115 2e-25
SPCC320.12c [D] KOG0580 Serine/threonine protein kinase 115 3e-25
HsM4507279 [D] KOG0580 Serine/threonine protein kinase 115 3e-25
SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase 115 4e-25
Hs5453972 [T] KOG0694 Serine/threonine protein kinase 115 4e-25
Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 115 4e-25
CE21239 [T] KOG0583 Serine/threonine protein kinase 115 4e-25
CE05507 [T] KOG0603 Ribosomal protein S6 kinase 115 4e-25
Hs4502023 [T] KOG0690 Serine/threonine protein kinase 114 5e-25
Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase... 114 5e-25
Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase 114 6e-25
At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 114 6e-25
HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase 114 8e-25
Hs7657214 [T] KOG0583 Serine/threonine protein kinase 114 8e-25
CE18454 [T] KOG4717 Serine/threonine protein kinase 114 8e-25
At1g01140 [T] KOG0583 Serine/threonine protein kinase 114 8e-25
Hs4507273 [D] KOG0580 Serine/threonine protein kinase 112 2e-24
ECU03g0980 [T] KOG0583 Serine/threonine protein kinase 112 2e-24
Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and r... 112 2e-24
CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 112 2e-24
7299536 [D] KOG0580 Serine/threonine protein kinase 112 2e-24
7293666 [D] KOG0575 Polo-like serine/threonine protein kinase 112 2e-24
CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 112 3e-24
7296450 [D] KOG0575 Polo-like serine/threonine protein kinase 112 3e-24
Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase 111 4e-24
CE21025 [D] KOG0580 Serine/threonine protein kinase 111 4e-24
At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 111 4e-24
Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase 110 7e-24
CE15612 [T] KOG0690 Serine/threonine protein kinase 110 7e-24
At5g57630 [T] KOG0583 Serine/threonine protein kinase 110 7e-24
Hs4885563 [T] KOG0694 Serine/threonine protein kinase 110 9e-24
Hs4759178 [D] KOG0580 Serine/threonine protein kinase 110 9e-24
Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase 110 9e-24
At2g45490 [D] KOG0580 Serine/threonine protein kinase 109 2e-23
Hs4885061 [T] KOG0690 Serine/threonine protein kinase 109 2e-23
Hs20545357 [T] KOG0583 Serine/threonine protein kinase 109 2e-23
CE24761 [D] KOG0580 Serine/threonine protein kinase 109 2e-23
Hs7661974 [T] KOG0583 Serine/threonine protein kinase 108 3e-23
Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 108 3e-23
Hs4885549 [T] KOG0690 Serine/threonine protein kinase 108 3e-23
Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PK... 108 3e-23
CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 108 3e-23
7300106 [T] KOG0690 Serine/threonine protein kinase 108 3e-23
Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase 108 3e-23
SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 108 3e-23
HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase 108 3e-23
Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 108 3e-23
SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 107 6e-23
At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 6e-23
7301213 [R] KOG0589 Serine/threonine protein kinase 107 6e-23
7299322 [R] KOG0611 Predicted serine/threonine protein kinase 107 6e-23
SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-speci... 107 8e-23
Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 107 8e-23
7302860 [T] KOG0696 Serine/threonine protein kinase 107 8e-23
Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 107 1e-22
Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase 107 1e-22
CE29092 [T] KOG0694 Serine/threonine protein kinase 107 1e-22
CE28479 [T] KOG0583 Serine/threonine protein kinase 107 1e-22
CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 107 1e-22
CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 107 1e-22
SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase 106 1e-22
CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD a... 106 1e-22
SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 an... 106 2e-22
Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 106 2e-22
Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 106 2e-22
7297080 [T] KOG0583 Serine/threonine protein kinase 106 2e-22
Hs20547806 [R] KOG0589 Serine/threonine protein kinase 105 2e-22
CE17284 [T] KOG0583 Serine/threonine protein kinase 105 2e-22
CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 105 2e-22
CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase 105 2e-22
CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 105 3e-22
7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 105 3e-22
7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 105 3e-22
Hs14735945 [T] KOG0694 Serine/threonine protein kinase 105 4e-22
Hs5453970 [T] KOG0694 Serine/threonine protein kinase 104 5e-22
Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 104 5e-22
Hs20547878 [R] KOG0589 Serine/threonine protein kinase 104 5e-22
Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 104 5e-22
At4g32830 [D] KOG0580 Serine/threonine protein kinase 104 5e-22
SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase 104 6e-22
Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD... 104 6e-22
Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase 104 6e-22
ECU07g0360 [D] KOG0580 Serine/threonine protein kinase 104 6e-22
ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase 104 6e-22
At2g25880 [D] KOG0580 Serine/threonine protein kinase 104 6e-22
Hs4506067 [T] KOG0696 Serine/threonine protein kinase 103 8e-22
CE02586 [T] KOG0696 Serine/threonine protein kinase 103 8e-22
At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 103 8e-22
7297776 [D] KOG0580 Serine/threonine protein kinase 103 8e-22
YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 103 1e-21
Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 103 1e-21
7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 103 1e-21
Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase ... 103 1e-21
At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine k... 103 1e-21
Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 102 2e-21
Hs16507245 [T] KOG0583 Serine/threonine protein kinase 102 2e-21
CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase 102 2e-21
YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 102 3e-21
YLR096w [T] KOG0583 Serine/threonine protein kinase 102 3e-21
Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase 102 3e-21
At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine k... 102 3e-21
7302861 [T] KOG0696 Serine/threonine protein kinase 102 3e-21
Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase... 102 3e-21
Hs22068916 [T] KOG0696 Serine/threonine protein kinase 101 4e-21
Hs20127450 [T] KOG0696 Serine/threonine protein kinase 101 4e-21
Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2 101 4e-21
Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2 101 4e-21
CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase 101 4e-21
At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 101 4e-21
Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and relate... 101 4e-21
YKL101w [D] KOG0588 Serine/threonine protein kinase 101 5e-21
Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine prote... 101 5e-21
At3g17510 [T] KOG0583 Serine/threonine protein kinase 100 7e-21
YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 100 9e-21
At3g06030 [T] KOG0198 MEKK and related serine/threonine protein ... 100 9e-21
7299793 [T] KOG0583 Serine/threonine protein kinase 100 9e-21
YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 100 1e-20
Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase 100 1e-20
Hs4506073 [T] KOG0694 Serine/threonine protein kinase 100 1e-20
Hs14758219 [T] KOG0694 Serine/threonine protein kinase 100 1e-20
Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 100 1e-20
CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase 100 1e-20
At3g07980 [T] KOG0198 MEKK and related serine/threonine protein ... 100 1e-20
YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 100 2e-20
Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase 100 2e-20
At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 100 2e-20
SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kina... 99 2e-20
SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related... 99 2e-20
Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases 99 2e-20
Hs14042947 [T] KOG0583 Serine/threonine protein kinase 99 2e-20
CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 99 2e-20
CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 99 2e-20
At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 99 2e-20
At3g20860 [R] KOG0589 Serine/threonine protein kinase 99 2e-20
SPAC644.06c [D] KOG0588 Serine/threonine protein kinase 99 3e-20
Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit 99 3e-20
At5g28290 [R] KOG0589 Serine/threonine protein kinase 99 3e-20
At3g13530 [T] KOG0198 MEKK and related serine/threonine protein ... 99 3e-20
7304311 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 99 3e-20
7304283 [Z] KOG0613 Projectin/twitchin and related proteins 99 3e-20
7290629 [T] KOG0604 MAP kinase-activated protein kinase 2 99 3e-20
Hs5453974 [T] KOG0694 Serine/threonine protein kinase 99 3e-20
Hs20070158 [T] KOG0201 Serine/threonine protein kinase 99 3e-20
CE22045 [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 99 3e-20
CE03232 [D] KOG0591 NIMA (never in mitosis)-related G2-specific ... 99 3e-20
7297542 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 99 3e-20
7292679 [G] KOG0599 Phosphorylase kinase gamma subunit 99 3e-20
Hs4758700 [T] KOG0604 MAP kinase-activated protein kinase 2 98 5e-20
At2g31500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 5e-20
At1g63700 [T] KOG0198 MEKK and related serine/threonine protein ... 98 5e-20
YOL016c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 98 6e-20
YDR523c [T] KOG0201 Serine/threonine protein kinase 98 6e-20
Hs4506739 [RT] KOG0598 Ribosomal protein S6 kinase and related p... 98 6e-20
CE07285 [D] KOG0575 Polo-like serine/threonine protein kinase 98 6e-20
CE01405 [T] KOG0577 Serine/threonine protein kinase 98 6e-20
At4g04740 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 98 6e-20
Hs6382058 [T] KOG4278 Protein tyrosine kinase 97 8e-20
Hs4885045 [T] KOG4278 Protein tyrosine kinase 97 8e-20
CE03979 [T] KOG0614 cGMP-dependent protein kinase 97 8e-20
At4g33950 [T] KOG0583 Serine/threonine protein kinase 97 8e-20
At1g54510 [R] KOG0589 Serine/threonine protein kinase 97 8e-20
7301972 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 97 8e-20
7294076 [T] KOG4278 Protein tyrosine kinase 97 8e-20
7290147 [T] KOG0583 Serine/threonine protein kinase 97 8e-20
YNL298w [T] KOG0578 p21-activated serine/threonine protein kinase 97 1e-19
YAR019c [T] KOG0198 MEKK and related serine/threonine protein ki... 97 1e-19
SPCC16C4.11 [R] KOG0594 Protein kinase PCTAIRE and related kinases 97 1e-19
Hs7706059 [R] KOG0593 Predicted protein kinase KKIAMRE 97 1e-19
Hs20538863 [T] KOG4250 TANK binding protein kinase TBK1 97 1e-19
At5g04870 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 1e-19
7303111 [T] KOG0695 Serine/threonine protein kinase 97 1e-19
YHR205w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 97 1e-19
Hs4826948 [T] KOG0616 cAMP-dependent protein kinase catalytic su... 97 1e-19
Hs4506071 [T] KOG0695 Serine/threonine protein kinase 97 1e-19
CE28251 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 97 1e-19
At3g04810 [R] KOG0589 Serine/threonine protein kinase 97 1e-19
At2g46700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 97 1e-19
YFR014c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 96 2e-19
Hs5032001 [T] KOG4257 Focal adhesion tyrosine kinase FAK contain... 96 2e-19
Hs4885583 [T] KOG0612 Rho-associated coiled-coil containing prot... 96 2e-19
Hs20535816 [T] KOG0695 Serine/threonine protein kinase 96 2e-19
Hs10864650 [T] KOG0695 Serine/threonine protein kinase 96 2e-19
At4g38230 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
At4g04700 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
7292656 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 96 2e-19
At2g41140 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 96 2e-19
7300650 [R] KOG0594 Protein kinase PCTAIRE and related kinases 96 2e-19
Hs14150045 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase ... 96 3e-19
CE27965 [T] KOG0574 STE20-like serine/threonine kinase MST 96 3e-19
CE27726 [T] KOG0574 STE20-like serine/threonine kinase MST 96 3e-19
CE27082 [T] KOG0574 STE20-like serine/threonine kinase MST 96 3e-19
CE07064 [T] KOG0574 STE20-like serine/threonine kinase MST 96 3e-19
CE06635 [Z] KOG0613 Projectin/twitchin and related proteins 96 3e-19
CE06634 [Z] KOG0613 Projectin/twitchin and related proteins 96 3e-19
At3g17850 [TR] KOG0606 Microtubule-associated serine/threonine k... 96 3e-19
At1g53570 [T] KOG0198 MEKK and related serine/threonine protein ... 96 3e-19
7300778 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-... 96 3e-19
YKL126w [RT] KOG0598 Ribosomal protein S6 kinase and related pro... 95 4e-19
Hs4507271 [T] KOG0583 Serine/threonine protein kinase 95 4e-19
Hs13384594 [T] KOG0696 Serine/threonine protein kinase 95 4e-19
ECU11g1500 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase ... 95 4e-19
CE23001 [R] KOG0589 Serine/threonine protein kinase 95 4e-19
CE19898 [T] KOG0614 cGMP-dependent protein kinase 95 4e-19
CE19897 [T] KOG0614 cGMP-dependent protein kinase 95 4e-19
At3g51850 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 4e-19
CE17458 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 95 5e-19
CE17457 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 95 5e-19
At4g35310 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 5e-19
At2g41860 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 95 5e-19
7303915 [T] KOG0694 Serine/threonine protein kinase 95 5e-19
7303914 [T] KOG0694 Serine/threonine protein kinase 95 5e-19
CE27131_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase E... 95 5e-19
SPAC1F5.09c [T] KOG0578 p21-activated serine/threonine protein k... 94 7e-19
CE18608 [R] KOG0594 Protein kinase PCTAIRE and related kinases 94 7e-19
CE18169 [T] KOG0603 Ribosomal protein S6 kinase 94 7e-19
CE13014 [T] KOG0603 Ribosomal protein S6 kinase 94 7e-19
At5g23580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 7e-19
At1g66880 [T] KOG1187 Serine/threonine protein kinase 94 7e-19
7301971 [T] KOG0616 cAMP-dependent protein kinase catalytic subu... 94 7e-19
CE28650 [OUT] KOG0595 Serine/threonine-protein kinase involved i... 94 9e-19
CE09360 [Z] KOG0613 Projectin/twitchin and related proteins 94 9e-19
At3g10660 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 9e-19
At2g38910 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 9e-19
Hs19311016_1 [R] KOG0589 Serine/threonine protein kinase 94 9e-19
CE21086 [D] KOG0590 Checkpoint kinase and related serine/threoni... 94 1e-18
CE20258 [R] KOG0593 Predicted protein kinase KKIAMRE 94 1e-18
CE02604 [T] KOG0695 Serine/threonine protein kinase 94 1e-18
At4g23650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At3g45240 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 94 1e-18
At2g17290 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 94 1e-18
At1g18390 [T] KOG1187 Serine/threonine protein kinase 94 1e-18
7297680 [R] KOG0594 Protein kinase PCTAIRE and related kinases 94 1e-18
Hs19923464 [T] KOG0577 Serine/threonine protein kinase 93 1e-18
Hs16936528 [R] KOG0594 Protein kinase PCTAIRE and related kinases 93 1e-18
Hs14042966 [T] KOG0583 Serine/threonine protein kinase 93 1e-18
At3g04530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 1e-18
At1g14000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 93 1e-18
YDR122w [T] KOG0583 Serine/threonine protein kinase 93 2e-18
Hs5453978 [T] KOG0614 cGMP-dependent protein kinase 93 2e-18
Hs5174701 [T] KOG0579 Ste20-like serine/threonine protein kinase 93 2e-18
Hs19923570 [T] KOG0603 Ribosomal protein S6 kinase 93 2e-18
Hs16950621 [Z] KOG0613 Projectin/twitchin and related proteins 93 2e-18
Hs16950613 [Z] KOG0613 Projectin/twitchin and related proteins 93 2e-18
Hs16950611 [Z] KOG0613 Projectin/twitchin and related proteins 93 2e-18
Hs16950601 [Z] KOG0613 Projectin/twitchin and related proteins 93 2e-18
CE27297 [D] KOG0615 Serine/threonine protein kinase Chk2 and rel... 93 2e-18
At3g10540 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 93 2e-18
At3g01490 [T] KOG0192 Tyrosine kinase specific for activated (GT... 93 2e-18
At1g08650 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 93 2e-18
Hs6382062 [T] KOG4278 Protein tyrosine kinase 92 3e-18
Hs6382060 [T] KOG4278 Protein tyrosine kinase 92 3e-18
Hs10835242 [T] KOG0614 cGMP-dependent protein kinase 92 3e-18
7302478 [T] KOG4257 Focal adhesion tyrosine kinase FAK contains ... 92 3e-18
7295638 [T] KOG0603 Ribosomal protein S6 kinase 92 3e-18
HsM5454174 [T] KOG0201 Serine/threonine protein kinase 92 3e-18
Hs7706401 [T] KOG0577 Serine/threonine protein kinase 92 3e-18
Hs4759208 [T] KOG0577 Serine/threonine protein kinase 92 3e-18
Hs4557439 [R] KOG0594 Protein kinase PCTAIRE and related kinases 92 3e-18
Hs21361358 [T] KOG0201 Serine/threonine protein kinase 92 3e-18
At5g60550 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase k... 92 3e-18
At1g48260 [T] KOG0583 Serine/threonine protein kinase 92 3e-18
Hs7657526 [T] KOG0603 Ribosomal protein S6 kinase 92 4e-18
Hs10835065 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 92 4e-18
At5g04510 [T] KOG0592 3-phosphoinositide-dependent protein kinas... 92 4e-18
At3g50530 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 92 4e-18
7301004 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 92 4e-18
7296128 [T] KOG0583 Serine/threonine protein kinase 92 4e-18
SPCC4G3.08 [RT] KOG0598 Ribosomal protein S6 kinase and related ... 91 6e-18
Hs20070174 [T] KOG4257 Focal adhesion tyrosine kinase FAK contai... 91 6e-18
CE20636 [D] KOG0590 Checkpoint kinase and related serine/threoni... 91 6e-18
7302458 [T] KOG0574 STE20-like serine/threonine kinase MST 91 6e-18
Hs16418343 [T] KOG0583 Serine/threonine protein kinase 91 7e-18
At2g24360 [T] KOG0192 Tyrosine kinase specific for activated (GT... 91 7e-18
At1g69220 [T] KOG0576 Mitogen-activated protein kinase kinase ki... 91 7e-18
7300224 [T] KOG0201 Serine/threonine protein kinase 91 7e-18
CE28918 [R] KOG0594 Protein kinase PCTAIRE and related kinases 91 1e-17
At4g08500 [T] KOG0198 MEKK and related serine/threonine protein ... 91 1e-17
At1g66750 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 91 1e-17
At1g09600 [D] KOG0600 Cdc2-related protein kinase 91 1e-17
CE28674 [T] KOG0201 Serine/threonine protein kinase 90 1e-17
CE07510 [T] KOG0201 Serine/threonine protein kinase 90 1e-17
CE00315 [R] KOG0594 Protein kinase PCTAIRE and related kinases 90 1e-17
Hs7019489 [T] KOG0694 Serine/threonine protein kinase 90 2e-17
Hs5453882 [G] KOG0599 Phosphorylase kinase gamma subunit 90 2e-17
CE17354 [T] KOG0694 Serine/threonine protein kinase 90 2e-17
CE17353 [T] KOG0694 Serine/threonine protein kinase 90 2e-17
At5g38210 [T] KOG1187 Serine/threonine protein kinase 90 2e-17
At1g25390 [T] KOG1187 Serine/threonine protein kinase 90 2e-17
SPBC1D7.05c [T] KOG0198 MEKK and related serine/threonine protei... 89 2e-17
SPAC9G1.09 [T] KOG0201 Serine/threonine protein kinase 89 2e-17
CE01146 [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 89 2e-17
At4g35780 [T] KOG0192 Tyrosine kinase specific for activated (GT... 89 2e-17
7300329 [T] KOG0200 Fibroblast/platelet-derived growth factor re... 89 2e-17
7297611 [T] KOG0614 cGMP-dependent protein kinase 89 2e-17
SPAC23H4.02 [T] KOG0583 Serine/threonine protein kinase 89 3e-17
SPAC22E12.14c [RT] KOG0598 Ribosomal protein S6 kinase and relat... 89 3e-17
At1g73690 [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymera... 89 3e-17
7291043 [T] KOG0660 Mitogen-activated protein kinase 89 3e-17
YPL141c [T] KOG0583 Serine/threonine protein kinase 89 4e-17
SPAC1F3.02c [T] KOG0198 MEKK and related serine/threonine protei... 89 4e-17
CE28571 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-... 89 4e-17
CE18646 [T] KOG0690 Serine/threonine protein kinase 89 4e-17
At1g53050 [D] KOG0600 Cdc2-related protein kinase 89 4e-17
Hs4758702 [T] KOG4279 Serine/threonine protein kinase 88 5e-17
Hs19923134 [T] KOG4250 TANK binding protein kinase TBK1 88 5e-17
CE29453 [T] KOG0192 Tyrosine kinase specific for activated (GTP-... 88 5e-17
CE29298 [T] KOG0690 Serine/threonine protein kinase 88 5e-17
CE20717 [T] KOG0583 Serine/threonine protein kinase 88 5e-17
At2g35890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 5e-17
At2g17890 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 88 5e-17
7296166 [T] KOG0614 cGMP-dependent protein kinase 88 5e-17
SPAC890.03 [T] KOG0583 Serine/threonine protein kinase 88 6e-17
Hs4758652 [R] KOG0593 Predicted protein kinase KKIAMRE 88 6e-17
ECU07g0520 [T] KOG0616 cAMP-dependent protein kinase catalytic s... 88 6e-17
At1g54960 [T] KOG0198 MEKK and related serine/threonine protein ... 88 6e-17
At1g53165 [T] KOG0201 Serine/threonine protein kinase 88 6e-17
YPL031c [R] KOG0594 Protein kinase PCTAIRE and related kinases 87 8e-17
YDR466w [T] KOG0592 3-phosphoinositide-dependent protein kinase ... 87 8e-17
Hs4505569 [R] KOG0593 Predicted protein kinase KKIAMRE 87 8e-17
At1g12680 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 8e-17
At1g09000 [T] KOG0198 MEKK and related serine/threonine protein ... 87 8e-17
Hs4885631 [T] KOG0200 Fibroblast/platelet-derived growth factor ... 87 1e-16
CE26967 [T] KOG0199 ACK and related non-receptor tyrosine kinases 87 1e-16
At4g31170 [T] KOG0192 Tyrosine kinase specific for activated (GT... 87 1e-16
At1g62400 [T] KOG0192 Tyrosine kinase specific for activated (GT... 87 1e-16
YGL179c [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kin... 87 1e-16
At5g66210 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase E... 87 1e-16
7293761 [T] KOG4721 Serine/threonine protein kinase contains leu... 87 1e-16
SPBC19C2.05 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
Hs17461944 [R] KOG0593 Predicted protein kinase KKIAMRE 86 2e-16
At3g15220 [T] KOG0201 Serine/threonine protein kinase 86 2e-16
YJL095w [T] KOG0198 MEKK and related serine/threonine protein ki... 86 2e-16
YBR160w [R] KOG0594 Protein kinase PCTAIRE and related kinases 86 2e-16
Hs4885231 [T] KOG0194 Protein tyrosine kinase 86 2e-16
Hs4504357 [T] KOG0197 Tyrosine kinases 86 2e-16
Hs21040235 [R] KOG0594 Protein kinase PCTAIRE and related kinases 86 2e-16
Hs13653487 [T] KOG0197 Tyrosine kinases 86 2e-16
CE17343 [T] KOG0583 Serine/threonine protein kinase 86 2e-16
7297578 [T] KOG0661 MAPK related serine/threonine protein kinase 86 2e-16
SPBC4C3.11 [T] KOG0592 3-phosphoinositide-dependent protein kina... 86 3e-16
ECU08g1920 [R] KOG0594 Protein kinase PCTAIRE and related kinases 86 3e-16
ECU08g1790 [D] KOG0600 Cdc2-related protein kinase 86 3e-16
CE21401 [G] KOG0658 Glycogen synthase kinase-3 86 3e-16
CE06762 [T] KOG0660 Mitogen-activated protein kinase 86 3e-16
At2g17700 [T] KOG0192 Tyrosine kinase specific for activated (GT... 86 3e-16
Hs4758696 [T] KOG4721 Serine/threonine protein kinase contains l... 85 4e-16
Hs4506785 [T] KOG0660 Mitogen-activated protein kinase 85 4e-16
Hs20986529 [T] KOG0660 Mitogen-activated protein kinase 85 4e-16
Hs18579683 [R] KOG0605 NDR and related serine/threonine kinases 85 4e-16
At4g22940 [D] KOG0600 Cdc2-related protein kinase 85 4e-16
At4g18710 [G] KOG0658 Glycogen synthase kinase-3 85 4e-16
At1g18670 [D] KOG0600 Cdc2-related protein kinase 85 4e-16
7300098 [T] KOG4250 TANK binding protein kinase TBK1 85 4e-16
Hs6005814 [R] KOG0605 NDR and related serine/threonine kinases 85 5e-16
Hs20986531 [T] KOG0660 Mitogen-activated protein kinase 85 5e-16
At4g23050 [T] KOG0192 Tyrosine kinase specific for activated (GT... 85 5e-16
At1g74330 [D] KOG0600 Cdc2-related protein kinase 85 5e-16
YOR233w [T] KOG0583 Serine/threonine protein kinase 84 7e-16
Hs4507281 [R] KOG0593 Predicted protein kinase KKIAMRE 84 7e-16
Hs4506529 [T] KOG0986 G protein-coupled receptor kinase 84 7e-16
CE27568 [T] KOG0199 ACK and related non-receptor tyrosine kinases 84 7e-16
CE03866 [T] KOG0199 ACK and related non-receptor tyrosine kinases 84 7e-16
At5g50000 [T] KOG0192 Tyrosine kinase specific for activated (GT... 84 7e-16
At3g18040 [T] KOG0660 Mitogen-activated protein kinase 84 7e-16
7290342 [G] KOG0658 Glycogen synthase kinase-3 84 7e-16
SPAC9G1.02 [T] KOG4645 MAPKKK (MAP kinase kinase kinase) SSK2 an... 84 9e-16
SPAC24B11.06c [T] KOG0660 Mitogen-activated protein kinase 84 9e-16
Hs7662388 [T] KOG0661 MAPK related serine/threonine protein kinase 84 9e-16
Hs5174647 [T] KOG0197 Tyrosine kinases 84 9e-16
Hs4503823 [T] KOG0197 Tyrosine kinases 84 9e-16
Hs4502741 [R] KOG0594 Protein kinase PCTAIRE and related kinases 84 9e-16
CE27583 [T] KOG0604 MAP kinase-activated protein kinase 2 84 9e-16
CE20493 [TR] KOG0606 Microtubule-associated serine/threonine kin... 84 9e-16
CE17545 [T] KOG0604 MAP kinase-activated protein kinase 2 84 9e-16
7298323 [D] KOG0590 Checkpoint kinase and related serine/threoni... 84 9e-16
7292519 [T] KOG0197 Tyrosine kinases 84 9e-16
SPBC1604.14c [T] KOG0578 p21-activated serine/threonine protein ... 84 1e-15
HsM4504163 [G] KOG0658 Glycogen synthase kinase-3 84 1e-15
Hs7705551 [T] KOG0661 MAPK related serine/threonine protein kinase 84 1e-15
CE23883 [T] KOG4278 Protein tyrosine kinase 84 1e-15
CE21080 [T] KOG4278 Protein tyrosine kinase 84 1e-15
CE03506 [T] KOG4278 Protein tyrosine kinase 84 1e-15
At5g03730 [T] KOG0192 Tyrosine kinase specific for activated (GT... 84 1e-15
At1g67890 [T] KOG0192 Tyrosine kinase specific for activated (GT... 84 1e-15
At1g06390 [G] KOG0658 Glycogen synthase kinase-3 84 1e-15
CE02602_1 [T] KOG0660 Mitogen-activated protein kinase 84 1e-15
YCR091w [R] KOG0610 Putative serine/threonine protein kinase 83 2e-15
SPAC57A10.02 [D] KOG0588 Serine/threonine protein kinase 83 2e-15
>YGL180w [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 897
Score = 753 bits (1944), Expect = 0.0
Identities = 439/900 (48%), Positives = 568/900 (62%), Gaps = 80/900 (8%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKG-LSLRDGRNIAIKAVSRSXXXX 59
+ ++ H V + NY+ EKEIGKGSFA VY+G L+ +++AIK VSR+
Sbjct: 4 IKNKDHTTSVNHNLMASAGNYTAEKEIGKGSFATVYRGHLTSDKSQHVAIKEVSRAKLKN 63
Query: 60 XXXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLK 119
+EIAILKKIKHPHIVGLIDCERTS+DFYLIMEYCALGDLTF +K+RK L+
Sbjct: 64 KKLLENLEIEIAILKKIKHPHIVGLIDCERTSTDFYLIMEYCALGDLTFLLKRRKELMEN 123
Query: 120 HPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTP 179
HPL++TVFE YPPPS HNGL+R V++YLQQL+SALKFLRSKNLVHRDIKPQNLLL TP
Sbjct: 124 HPLLRTVFEKYPPPSENHNGLHRAFVLSYLQQLASALKFLRSKNLVHRDIKPQNLLLSTP 183
Query: 180 LLDYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQK 239
L+ Y+D K+FHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQK
Sbjct: 184 LIGYHDSKSFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQK 243
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
YNAKADLWSVGTV++EMCCG PPF+ASNHLELF+KIK+AND IT PS C IEP+L LI
Sbjct: 244 YNAKADLWSVGTVVFEMCCGTPPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELIC 303
Query: 300 GLLTFDPDSRMGFTDFFNNEVVTEDLTRYEQSYE-PDLESKSKDVAESNMFVSEYLVKPL 358
LLTFDP R+GF +FF N+VV EDL+ YE + P+LESKSK + ESNMFVSEYL K
Sbjct: 304 SLLTFDPAQRIGFEEFFANKVVNEDLSSYELEDDLPELESKSKGIVESNMFVSEYLSKQP 363
Query: 359 K--------QQESAHIPPTQTD--ENTSVQTG----VRRTSGKERLATNHPPHQQIHPED 404
K Q A P +D +N+++ T T ++ A+N+ H +
Sbjct: 364 KSPNSNLAGHQSMADNPAELSDALKNSNILTAPAVKTDHTQAVDKKASNNKYHNSL---V 420
Query: 405 NSQNPEQSYQSASQKRLK-SSYNDLILXXXXXXXXXXXXXXNS-----LADDFA-NNGPI 457
+ ++ E+ Y +K ++ +S D + L + F+ NN
Sbjct: 421 SDRSFEREYVVVEKKSVEVNSLADEVAQAGFNPNPIKHPTSTQNQNVLLNEQFSPNNQQY 480
Query: 458 TNNQGAQVIKPLRYRTXXXXXXXXXXXXXLVERRXXXXXXXXXXXXXXXXGLASVRLFG- 516
NQG + LR + LV+RR G+AS RLFG
Sbjct: 481 FQNQGENP-RLLRATSSSSGGSDGSRRPSLVDRRLSISSLNPSNALSRALGIASTRLFGG 539
Query: 517 ---YQHNTKATSSPP-QQTLLNPQIFQELTENAVLRADHKLNPFSEQMLDSNITPAVESL 572
Q + TSSPP QTLLN Q+F ELTEN +LR DH +P + ++ ++NI +ESL
Sbjct: 540 ANQQQQQQQITSSPPYSQTLLNSQLFHELTENIILRIDHLQHPETLKLDNTNIVSILESL 599
Query: 573 AAKAFVMYSFAEMKFSQILPTPPSSTDYDPLSDKRLSNGSCAIEDEEDLDQGRPPSNQTL 632
AAKAFV+YS+AE+KFSQI+P + ++R S S AI +E+D D ++TL
Sbjct: 600 AAKAFVVYSYAEVKFSQIVPLSTTLKGMANFENRR-SMDSNAIAEEQDSDDAE-EEDETL 657
Query: 633 ------------------TSATTKISSATNVDTQIPAPELKKLCTESXXXXXXXXXXXXX 674
SAT+++S+ N ++P E+ LC E+
Sbjct: 658 KKYKEDCLSTKTFGKGRTLSATSQLSATFN---KLPRSEMILLCNEAIVLYMKALSILSK 714
Query: 675 SMKLTSKWWYENESKNCTLKLNILVQWIRDRFNECLDKAEFLRLKLH----------AIN 724
SM++TS WWYE++ K+C+L++N+LVQW+R++FNECL+KA+FLRLK++ A N
Sbjct: 715 SMQVTSNWWYESQEKSCSLRVNVLVQWLREKFNECLEKADFLRLKINDLRFKHASEVAEN 774
Query: 725 TSPNSQWSDDDPVIFVEKLIYDRALDISRNAARMEMESGNYNTCELAYATSLWMLEILLD 784
+ + S ++PV ++EKL+YDRAL+IS+ AA ME++ N CELAYATSLWMLE LD
Sbjct: 775 QTLEEKGSSEEPV-YLEKLLYDRALEISKMAAHMELKGENLYNCELAYATSLWMLETSLD 833
Query: 785 ENFQFNEVYDDEYASNI--------------TSLDESDKEMIKKYISSIANRLKALKSKM 830
++ N D + +NI + LDE+D+ +I+KYI SIANRLK L+ KM
Sbjct: 834 DDDFTNAYGDYPFKTNIHLKSNDVEDKEKYHSVLDENDRIIIRKYIDSIANRLKILRQKM 893
>SPCC63.08c [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 830
Score = 282 bits (722), Expect = 1e-75
Identities = 157/342 (45%), Positives = 213/342 (61%), Gaps = 16/342 (4%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + EIG+GSFA+VYKG R I+IK+V EI+ILK+I+H H
Sbjct: 14 YVIRSEIGRGSFAIVYKGKHTETNRVISIKSVLTKKLTKKLLENLES-EISILKEIRHVH 72
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V LIDC + +L+MEYC+LGDL++FI+KR+ L +H P GL
Sbjct: 73 VVELIDCIKAGRFIHLVMEYCSLGDLSYFIRKREKFNSIPSLAWINIDH---PPVYKAGL 129
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFH---ELGFVGI 197
N LV ++ QQL+SAL+FLRS++L+HRD+KPQNLLL P P + FVG
Sbjct: 130 NETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPP------PTAAYLEEHPQFVGS 183
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
LP+LK+ADFGFAR+L +S+AETLCGSPLYMAPEIL Y+KY+AKADLWSVG VLYEM
Sbjct: 184 PKLPMLKLADFGFARYLQTSSMAETLCGSPLYMAPEILRYEKYDAKADLWSVGAVLYEMA 243
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G+PPFKA NH+EL ++I+KA D I P +I P + LI LL +P R+ + FF+
Sbjct: 244 VGKPPFKAPNHVELLRRIQKAKDVIKFPEEAFIHPDIKTLICALLKQNPADRIDYDGFFS 303
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDV---AESNMFVSEYLVK 356
+ VVT L D++ K++ + S +++++ K
Sbjct: 304 SIVVTTPLDDASTLTGSDIQDAVKEINIPSSSPAYITDFFPK 345
Score = 66.2 bits (160), Expect = 2e-10
Identities = 67/287 (23%), Positives = 117/287 (40%), Gaps = 62/287 (21%)
Query: 550 DHKLNPFSEQMLDSN--ITPAVESLAAKAFVMYSFAEMKFSQILPTPPSSTDYDPLSDKR 607
D+ +N + D+ + +ES+A K+ +Y AE+K +QI+P+ LSD+
Sbjct: 579 DNNVNIIQPSLPDTGKRLLDVLESIAMKSNSVYHLAEVKLAQIIPS---------LSDEM 629
Query: 608 LSNGSCAIEDEEDLDQGRPPSNQTLTSATTKISSATNVDTQIPAPELKKLCTESXXXXXX 667
P + L T S L L ES
Sbjct: 630 ------------------KPGDTLLDRPLTPFS-------------LVMLAKESYVLYER 658
Query: 668 XXXXXXXSMKLTSKWWYENESKNCTLKLNILVQWIRDRFNECLDKAEFLR---LKLHAIN 724
+ + +W +E + + ++W R R++E L+K++FLR + A +
Sbjct: 659 DIELLQVAFDGVAAFWANSEER-ASPDCQQAIEWFRQRYSESLEKSQFLREIIISQSAAH 717
Query: 725 TSPNSQWSDDDPVIFVEKLIYDRALDISRNAARMEMESGNYNTCELAYATSLWMLEILLD 784
+ P ++ + +LIY RALD+SRNAA E+ + C Y + +LE LL+
Sbjct: 718 SLPTTK------PVSASQLIYHRALDLSRNAATSELSGNDAQACLQNYRLAAHLLESLLE 771
Query: 785 ENFQFNEVYDDEYASNITSLDESDKEMIKKYISSIANRLKALKSKMV 831
NF + + D ++ I+ I+ I R + L+SK +
Sbjct: 772 SNFSTPD----------GANDSNNSVTIRNLIALITKRQELLQSKQI 808
>At3g61960 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 648
Score = 185 bits (470), Expect = 2e-46
Identities = 107/306 (34%), Positives = 161/306 (51%), Gaps = 46/306 (15%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+Y++ IG GSFAVV+ G +A+K + + EI+IL I HP
Sbjct: 9 DYALGPRIGSGSFAVVWLAKHRSSGLEVAVKEIDKKLLSPKVRDNLLK-EISILSTIDHP 67
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+I+ + T +L++EYC+ GDL +I + H
Sbjct: 68 NIIRFYEAIETGDRIFLVLEYCSGGDLAGYINR------------------------HGK 103
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ + ++++QL+ L+ L+ K+ +HRD+KPQNLLL + +
Sbjct: 104 VPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSSKEVT----------------- 146
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
P+LKI DFGFAR L S+AET CGSPLYMAPEI+ QKY+AKADLWS G +L+++ G
Sbjct: 147 -PLLKIGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKYDAKADLWSAGAILFQLVTG 205
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNC--YIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
+PPF +NH++LF I + + E+ P + I P +L R LL +P R+ F +FFN
Sbjct: 206 KPPFDGNNHIQLFHNIVR-DTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFN 264
Query: 318 NEVVTE 323
+ + E
Sbjct: 265 HMFLRE 270
>At2g37840 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 181 bits (459), Expect = 4e-45
Identities = 105/269 (39%), Positives = 155/269 (57%), Gaps = 44/269 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+Y V ++IG GSF+VV++ DG +AIK ++ EI IL++I HP
Sbjct: 11 DYLVGRQIGSGSFSVVWEARHRVDGTEVAIKEIAMDRLNKKLQESLMS-EIFILRRINHP 69
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+I+ LID ++ +L++EYC GDL+ ++++ H ++ P + +H
Sbjct: 70 NIIRLIDMIKSPGKVHLVLEYCKGGDLSVYVQR-------HGIV-------PEATAKH-- 113
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
++QQL++ L+ LR N++HRD+KPQNLLL T + ND
Sbjct: 114 --------FMQQLAAGLQVLRDNNIIHRDLKPQNLLLST---NENDAD------------ 150
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
LKIADFGFAR L LAETLCGSPLYMAPEI+ QKY+AKADLWSVG +L+++ G
Sbjct: 151 ---LKIADFGFARSLQPRGLAETLCGSPLYMAPEIMQLQKYDAKADLWSVGAILFQLVTG 207
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNC 288
R PF ++ ++L Q I ++ E+ P +C
Sbjct: 208 RTPFTGNSQIQLLQNIIRST-ELHFPGDC 235
>CE24516 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 856
Score = 179 bits (454), Expect = 2e-44
Identities = 118/373 (31%), Positives = 188/373 (49%), Gaps = 50/373 (13%)
Query: 21 YSVEKEIGKGSFAVVYKGLSL-RDGRNIAIKAVSRSXXXXXXXXXXXXVEIAI-LKKIKH 78
YS +G G+FA+VY+G + R +AIKA+++ ++I L +KH
Sbjct: 9 YSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSLKH 68
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
++VGL+ C T + YL+ME+C GDL +++++ L
Sbjct: 69 ENLVGLLKCTETPTHVYLVMEFCNGGDLADYLQQKTTL---------------------- 106
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
N + +++ Q++ AL+ + K +VHRD+KPQN+LLC N+ +T + F I
Sbjct: 107 --NEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLC------NNSRTQNP-HFTDI- 156
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
++K+ADFGFARFL + +A TLCGSP+YMAPE++ +Y+AKADLWS+GT+L++
Sbjct: 157 ---VIKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMSMQYDAKADLWSIGTILFQCLT 213
Query: 259 GRPPFKASNHLELFQKIKKAND-EITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G+ PF A +L +K + +P C P L +L+ LL + R+ F DFFN
Sbjct: 214 GKAPFVAQTPPQLKAYYEKTRELRPNIPEWC--SPNLRDLLLRLLKRNAKDRISFEDFFN 271
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTSV 377
+ +T L P + + A S + + ++ P Q S +P
Sbjct: 272 HPFLTSPLL-------PSPSKRILESARSPLLANRRIITP---QSSLPVPKRAGSTKLDS 321
Query: 378 QTGVRRTSGKERL 390
T VRR R+
Sbjct: 322 PTPVRRIGESPRV 334
>Hs7662210 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1036
Score = 167 bits (423), Expect = 6e-41
Identities = 116/375 (30%), Positives = 184/375 (48%), Gaps = 47/375 (12%)
Query: 21 YSVEKEIGKGSFAVVYKGLSL-RDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
YS +G G+FAVV++G + +AIK++++ EI ILK+++H
Sbjct: 9 YSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGK--EIKILKELQHE 66
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L D + + +L+MEYC GDL +++ +
Sbjct: 67 NIVALYDVQELPNSVFLVMEYCNGGDLADYLQAK------------------------GT 102
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L+ + +L Q+++A++ L SK ++HRD+KPQN+ LL Y + + G
Sbjct: 103 LSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNI-----LLSYANRRKSSVSGI----- 152
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+KIADFGFAR+L + +A TLCGSP+YMAPE++ Q Y+AKADLWS+GTV+Y+ G
Sbjct: 153 --RIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVG 210
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
+PPF+A++ +L +K N + P L NL+ GLL + RM F FF++
Sbjct: 211 KPPFQANSPQDLRMFYEK-NRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHP 269
Query: 320 VVTEDLTRYE-----QSYEPDLESKSKDVAESNMFVSEYLVKPLK--QQESAHIPPTQTD 372
+ + + Y + S + S F S + ++ Q+E+ PP
Sbjct: 270 FLEQGPVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPP 329
Query: 373 ENTSVQTGVRRTSGK 387
V TS K
Sbjct: 330 NYLQVSKDSASTSSK 344
>Hs4507831 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 1050
Score = 167 bits (422), Expect = 8e-41
Identities = 102/300 (34%), Positives = 159/300 (53%), Gaps = 42/300 (14%)
Query: 21 YSVEKEIGKGSFAVVYKGLSL-RDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+S + IG G+FAVV+KG + +A+K +++ EI ILK++KH
Sbjct: 16 FSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGK--EIKILKELKHE 73
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L D + ++ YL+MEYC GDL ++ + L
Sbjct: 74 NIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTL----------------------- 110
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ + +LQQ++ A++ L SK ++HRD+KPQN+LL P +P +
Sbjct: 111 -SEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIR--------- 160
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+KIADFGFAR+L + +A TLCGSP+YMAPE++ Q Y+ KADLWS+GT++Y+ G
Sbjct: 161 ---VKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTG 217
Query: 260 RPPFKASNHLELFQKIKKANDEI-TVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
+ PF+AS+ +L +K + T+P L L+ LL + RM F +FF++
Sbjct: 218 KAPFQASSPQDLRLFYEKNKTLVPTIPRE--TSAPLRQLLLALLQRNHKDRMDFDEFFHH 275
>7299160 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 520
Score = 164 bits (416), Expect = 4e-40
Identities = 104/297 (35%), Positives = 160/297 (53%), Gaps = 44/297 (14%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
++ + +++G GS+A VYK + AIK V S EI +L+++KH
Sbjct: 8 DFEILEKLGAGSYATVYKARHKKQRTYHAIKYVEMSTLSQTSRENLIT-EIRLLRELKHK 66
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L D + Y+++EYC G+L+ FI+ +K L P ST
Sbjct: 67 YIVTLQDFFWDDKNIYIVLEYCNAGNLSAFIRTKKAL---------------PESTCRY- 110
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+L+QL++A++++R+ ++ H D+KPQNLLL G N
Sbjct: 111 --------FLRQLAAAVQYMRANDVSHFDLKPQNLLLTR-----------------GANN 145
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+ LK+ADFGFA+ L + + L GSPLYMAPEI+ +Y+AKADLWS+G +LYE G
Sbjct: 146 VS-LKVADFGFAQHLKLGEINQQLKGSPLYMAPEIVRKHQYDAKADLWSIGVILYECLFG 204
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
+ P+ + EL +I+KA + IT+P N I + +L+R LL +P +R+ F DFF
Sbjct: 205 KAPYSSRTIEELLLRIRKA-EAITLPPNARISNECHDLLRRLLAHEPTARISFADFF 260
>7294537 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 835
Score = 161 bits (408), Expect = 3e-39
Identities = 117/363 (32%), Positives = 180/363 (49%), Gaps = 46/363 (12%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAI-LKKIKHP 79
YS + +G G+FAVVYKG + +AIK +++ ++I L ++ H
Sbjct: 9 YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTELHHE 68
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
++V L+DC+ + L+MEYC GDL ++ + L
Sbjct: 69 NVVALLDCKESQDCVSLVMEYCNGGDLADYLSVKGTL----------------------- 105
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ V +L QL+ A+K L +K +VHRD+KPQN+LL +N KT +
Sbjct: 106 -SEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILL-----SHNYGKTLPAPSKI---- 155
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
LKIADFGFARFL ++A TLCGSP+YMAPE++ +Y++KADLWS+GT++Y+ G
Sbjct: 156 --TLKIADFGFARFLNEGAMAATLCGSPMYMAPEVIMSLQYDSKADLWSLGTIVYQCLTG 213
Query: 260 RPPFKAS--NHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
+ PF A N L+ + + + AN +PS + P L +L+ LL + R+ + FF
Sbjct: 214 KAPFYAQTPNELKSYYE-QNANLAPKIPSG--VSPDLRDLLLCLLRRNSKDRISYESFFV 270
Query: 318 NEVVTEDLTRYEQSYEPDL----ESKSKDVAESNMFVSEYLVKPLKQQE-SAHIPPTQTD 372
+ + P L +K+K + + LVK +QQ+ Q D
Sbjct: 271 HRFLQGKKAAVSPVDMPPLGGTPPAKAKSPLQQQLEQELKLVKLAEQQQKEREEQEAQED 330
Query: 373 ENT 375
ENT
Sbjct: 331 ENT 333
>7294217 [D] KOG0588 Serine/threonine protein kinase
Length = 851
Score = 144 bits (364), Expect = 4e-34
Identities = 102/338 (30%), Positives = 157/338 (46%), Gaps = 56/338 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +EK +GKG +V G+ G+ +AIK ++R EIAI+K I HPH
Sbjct: 18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVER-EIAIMKLIDHPH 76
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
++GL D YLI+E+ + G+L ++ K+ L K
Sbjct: 77 VLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEAR------------------ 118
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ +Q+ SAL F S ++ HRD+KP+NLLL D K
Sbjct: 119 ------KFFRQIISALDFCHSHSICHRDLKPENLLL--------DEKNN----------- 153
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFG A P S+ ET CGSP Y PE++ +KY+ KAD+WS G +LY + G
Sbjct: 154 --IKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PF N +L +K+K+ I ++ P +L+RG++ +PD R+ + +
Sbjct: 212 ALPFDDDNLRQLLEKVKRGVFHIP----HFVPPDCQSLLRGMIEVNPDRRLTLAEINRHP 267
Query: 320 VVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKP 357
VT E +LE +V ++++ + V P
Sbjct: 268 WVTAG-----GKGELELELPMMEVVQTHVIPTATAVDP 300
>CE00847 [T] KOG0583 Serine/threonine protein kinase
Length = 622
Score = 141 bits (356), Expect = 4e-33
Identities = 101/325 (31%), Positives = 152/325 (46%), Gaps = 53/325 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
N+ +++ IGKG+F V +G ++ G ++AIK ++R EI L+K+ HP
Sbjct: 23 NFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHP 82
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI L T SD +L+ME + G+L +I ++ L ++
Sbjct: 83 HITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESR----------------- 125
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
Y QQ+ S + + + +VHRD+KP+NL LLD N
Sbjct: 126 -------RYFQQIISGVSYCHNHMIVHRDLKPENL-----LLDANKN------------- 160
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + ++ + L T CGSP Y APE+++ + Y + DLWS G +LY M C
Sbjct: 161 ---IKIADFGLSNYMTDGDLLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLC 217
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N LF KIK + TVP + +E + +LI +L DP R N+
Sbjct: 218 GTLPFDDQNVPTLFAKIK--SGRYTVPYS--MEKQAADLISTMLQVDPVKRADVKRIVNH 273
Query: 319 EVVTEDLTRYEQSYEPDLESKSKDV 343
DL Y P+ E++S V
Sbjct: 274 SWFRIDLPYY---LFPECENESSIV 295
>CE28218 [D] KOG0588 Serine/threonine protein kinase
Length = 914
Score = 139 bits (351), Expect = 1e-32
Identities = 96/338 (28%), Positives = 154/338 (45%), Gaps = 56/338 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +EK +GKG +V G GR +AIK V++ EIAI+K I+HPH
Sbjct: 47 YKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVER-EIAIMKLIEHPH 105
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
++ L D YL++E+ + G+L ++ ++ L+ K
Sbjct: 106 VLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEAR------------------ 147
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ +Q+ SAL F + N+ HRD+KP+NLLL + N+
Sbjct: 148 ------KFFRQIISALDFCHAHNICHRDLKPENLLLD----ERNN--------------- 182
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+K+ADFG A S+ ET CGSP Y PE++ +KY+ KAD+WS G +LY + G
Sbjct: 183 --IKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 240
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PF N L +K+K+ I ++ + +L+R ++ DP R D F +
Sbjct: 241 ALPFDDDNLRNLLEKVKRGVFHIP----HFVPADVQSLLRAMIEVDPGKRYSLADVFKHP 296
Query: 320 VVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKP 357
V+ +P+LE V ++++ E + P
Sbjct: 297 WVSG-----TTKADPELELPMSQVVQTHVIPGEDSIDP 329
>At3g53930 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 691
Score = 139 bits (351), Expect = 1e-32
Identities = 105/322 (32%), Positives = 153/322 (46%), Gaps = 84/322 (26%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+Y+V ++IG GSF+VV++G L G +AIK ++ + EI IL+KI HP
Sbjct: 19 DYAVGRQIGSGSFSVVWEGRHLVHGTVVAIKEIAMARLNKKLQESLMS-EIIILRKINHP 77
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+I+ ID L++EYC GDL+ +I K H
Sbjct: 78 NIIRFIDMIEAPGKINLVLEYCKGGDLSMYIHK------------------------HGS 113
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQ-------NLLLCTPLLDYNDPKTFHEL 192
+ +++ QL++ L+ LR N++HRD+KPQ NLLL T D ND
Sbjct: 114 VPEATAKHFMLQLAAGLQVLRDNNIIHRDLKPQVLSFLKQNLLLST---DDNDAA----- 165
Query: 193 GFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTV 252
LKIADFGFAR L LAETLCGSPLYMAPEI+ QKY+AK
Sbjct: 166 ----------LKIADFGFARSLQPRGLAETLCGSPLYMAPEIMQLQKYDAK--------- 206
Query: 253 LYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCY-IEPKLFNLIRGLLTFDPDSRMG 311
L Q I ++ E+ P++C + +L + LL +P R+
Sbjct: 207 ------------------LLQNIIRST-ELHFPADCRDLSTDCKDLCQKLLRRNPVERLT 247
Query: 312 FTDFFNNEVVTEDLTRYEQSYE 333
F +FF++ +++ +QSY+
Sbjct: 248 FEEFFHHPFLSD-----KQSYD 264
>Hs14754789 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 257
Score = 138 bits (348), Expect = 3e-32
Identities = 86/237 (36%), Positives = 125/237 (52%), Gaps = 45/237 (18%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNI-AIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
+ + + + +G G++A VYK + +D R + AIK V++ EI ILK I+
Sbjct: 55 DGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLT-EIEILKGIR 113
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HPHIV L D + S + YLIME+CA GDL+ FI R+ L K +
Sbjct: 114 HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARV-------------- 159
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
++QQL+SAL+FL +N+ H D+KPQN+LL +
Sbjct: 160 ----------FMQQLASALQFLHERNISHLDLKPQNILLSS------------------- 190
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
P LK+ADFGFA+ + L GSPLYMAPE++ ++Y+A+ DLWS+G +LY
Sbjct: 191 LEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILY 247
>Hs20545245 [D] KOG0588 Serine/threonine protein kinase
Length = 795
Score = 135 bits (339), Expect = 3e-31
Identities = 91/291 (31%), Positives = 140/291 (47%), Gaps = 51/291 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +EK +GKG +V G+ G+ +AIK V+R EIAILK I+HPH
Sbjct: 51 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVER-EIAILKLIEHPH 109
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
++ L D YL++E+ + G+L ++ K+ L K
Sbjct: 110 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEAR------------------ 151
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ +Q+ SAL F S ++ HRD+KP+NLLL D K
Sbjct: 152 ------KFFRQIVSALDFCHSYSICHRDLKPENLLL--------DEKNN----------- 186
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
++IADFG A SL ET CGSP Y PE++ +KY+ +AD+WS G +L+ + G
Sbjct: 187 --IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVG 244
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PF N +L +K+K+ +P +I P +L+RG++ +P+ R+
Sbjct: 245 ALPFDDDNLRQLLEKVKRG--VFHMPH--FIPPDCQSLLRGMIEVEPEKRL 291
>At1g29230 [T] KOG0583 Serine/threonine protein kinase
Length = 520
Score = 135 bits (339), Expect = 3e-31
Identities = 100/345 (28%), Positives = 154/345 (43%), Gaps = 68/345 (19%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K +G G+FA VY +++ G +AIK + + EI+IL++++HP+
Sbjct: 74 YELGKLLGHGTFAKVYLAQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPY 133
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T S Y +MEY G+ L TV + P T
Sbjct: 134 IVHLFEVMATKSKIYFVMEYVGGGE----------------LFNTVAKGRLPEETAR--- 174
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
Y QQL S++ F + + HRD+KP+NLLL N
Sbjct: 175 ------RYFQQLISSVSFCHGRGVYHRDLKPENLLL---------------------DNK 207
Query: 201 PILKIADFGF---ARFLPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEM 256
LK++DFG A L L T CG+P Y+APE+L + Y+ AKAD+WS G +L+ +
Sbjct: 208 GNLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKADVWSCGVILFVL 267
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PF N + +++KI K E P + L L+ LL +PD+R+ +
Sbjct: 268 MAGHIPFYDKNIMVMYKKIYKG--EFRCPR--WFSSDLVRLLTRLLDTNPDTRITIPEIM 323
Query: 317 NNE------------VVTEDLTRYEQSYEPDLES--KSKDVAESN 347
N + + L R ++ E + S +S V+ES+
Sbjct: 324 KNRWFKKGFKHVKFYIEDDKLCREDEDEEEEASSSGRSSTVSESD 368
>Hs18552621 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 1315
Score = 134 bits (337), Expect = 6e-31
Identities = 98/319 (30%), Positives = 152/319 (46%), Gaps = 52/319 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E Y V + IG+GSF VYKG + +A+K + + EI I++ ++H
Sbjct: 2 EKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQR-EIEIMRGLRH 60
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV ++D T + ++ +Y A G+L ++ L P +
Sbjct: 61 PNIVHMLDSFETDKEVVVVTDY-AEGELFQILEDDGKL----------------PEDQVQ 103
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ QL SAL +L S ++HRD+KPQN+LL
Sbjct: 104 AI--------AAQLVSALYYLHSHRILHRDMKPQNILLAKG------------------- 136
Query: 199 NLPILKIADFGFARFLP-NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ DFGFAR + NT + ++ G+PLYM+PE++ + Y+ ADLWSVG +LYE+
Sbjct: 137 --GGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELA 194
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G PPF A++ +L I K D + PS I P N ++GLLT DP R+ + D
Sbjct: 195 VGTPPFYATSIFQLVSLILK--DPVRWPST--ISPCFKNFLQGLLTKDPRQRLSWPDLLY 250
Query: 318 NEVVTEDLTRYEQSYEPDL 336
+ + +T + PDL
Sbjct: 251 HPFIAGHVTIITEPAGPDL 269
>At5g58380 [T] KOG0583 Serine/threonine protein kinase
Length = 464
Score = 134 bits (336), Expect = 8e-31
Identities = 90/297 (30%), Positives = 146/297 (48%), Gaps = 54/297 (18%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
T+ Y V + +G+G+FA VY G S+ +++AIK + + EI++++ +
Sbjct: 9 TDKYDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVMRIAR 68
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP++V L + T + Y +MEYC G+L + K K
Sbjct: 69 HPNVVELYEVMATKTRIYFVMEYCKGGELFNKVAKGK----------------------- 105
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
L + Y QL +A+ F S+ + HRDIKP+NLLL D N+
Sbjct: 106 --LRDDVAWKYFYQLINAVDFCHSREVYHRDIKPENLLL-----DDNEN----------- 147
Query: 198 YNLPILKIADFGFARFLP---NTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVL 253
LK++DFG + L T CG+P Y+APE++N + Y+ KAD+WS G VL
Sbjct: 148 -----LKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYDGTKADIWSCGVVL 202
Query: 254 YEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ + G PF SN +E+++KI KA + PS + P++ L+ +L +P++R+
Sbjct: 203 FVLLAGYLPFHDSNLMEMYRKIGKA--DFKAPS--WFAPEVRRLLCKMLDPNPETRI 255
>At5g39440 [T] KOG0583 Serine/threonine protein kinase
Length = 494
Score = 132 bits (333), Expect = 2e-30
Identities = 92/321 (28%), Positives = 145/321 (44%), Gaps = 55/321 (17%)
Query: 5 SHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXX 64
S +K K + + NY + K +G GSFA V L + G +AIK ++RS
Sbjct: 4 SSEKTTNKLVSI-LPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEI 62
Query: 65 XXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIK 124
EI IL+ + HPHI+ + T +D Y++MEY G+L +I
Sbjct: 63 KVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYI-------------- 108
Query: 125 TVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYN 184
E L + QQ+ S +++ +VHRD+KP+N+LL +
Sbjct: 109 ----------VEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCN--- 155
Query: 185 DPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA 244
+KI DFG + + + +T CGSP Y APE+++ + Y
Sbjct: 156 ------------------IKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDV 197
Query: 245 DLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTF 304
D+WS G +LY + CG PF N +F+KIK+ T+P+ ++ +LI +L
Sbjct: 198 DIWSCGVILYALLCGTLPFDDENIPNVFEKIKRG--MYTLPN--HLSHFARDLIPRMLMV 253
Query: 305 DPDSRMGFTD-----FFNNEV 320
DP R+ T+ +FNN +
Sbjct: 254 DPTMRISITEIRQHPWFNNHL 274
>At5g45820 [T] KOG0583 Serine/threonine protein kinase
Length = 439
Score = 132 bits (332), Expect = 2e-30
Identities = 96/342 (28%), Positives = 158/342 (46%), Gaps = 57/342 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + +G+G+FA VY +++ G ++AIK + + EI++++ ++HPH
Sbjct: 12 YELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPH 71
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V L + + + Y MEY G+L + K K L
Sbjct: 72 VVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGK-------------------------L 106
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Y QQL A+ + S+ + HRD+KP+NL LLD N
Sbjct: 107 KENIARKYFQQLIGAIDYCHSRGVYHRDLKPENL-----LLDENGD-------------- 147
Query: 201 PILKIADFGFARFLPN---TSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEM 256
LKI+DFG + + L T CG+P Y+APE++ + Y+ AKAD+WS G VLY +
Sbjct: 148 --LKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWSCGVVLYVL 205
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PF N +E+++KI K E P+ + P++ L+ +L +P+SR+
Sbjct: 206 LAGFLPFHEQNLVEMYRKITKG--EFKCPN--WFPPEVKKLLSRILDPNPNSRIKIEKIM 261
Query: 317 NNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPL 358
N + + E P ES D S++ + + VKP+
Sbjct: 262 ENSWFQKGFKKIETPKSP--ESHQIDSLISDVHAA-FSVKPM 300
>At5g07070 [T] KOG0583 Serine/threonine protein kinase
Length = 456
Score = 132 bits (332), Expect = 2e-30
Identities = 92/297 (30%), Positives = 142/297 (46%), Gaps = 54/297 (18%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
TE Y V + +G+G+FA VY G S ++AIK + + EI++++ K
Sbjct: 9 TERYEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVMRIAK 68
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP++V L + T S Y ++EYC G+L + K K
Sbjct: 69 HPNVVELYEVMATKSRIYFVIEYCKGGELFNKVAKGK----------------------- 105
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
L + Y QL SA+ F S+ + HRDIKP+NL LLD ND
Sbjct: 106 --LKEDVAWKYFYQLISAVDFCHSRGVYHRDIKPENL-----LLDDNDN----------- 147
Query: 198 YNLPILKIADFGFARFLP---NTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVL 253
LK++DFG + L T CG+P Y+APE++N + Y KAD+WS G VL
Sbjct: 148 -----LKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYEGTKADIWSCGVVL 202
Query: 254 YEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ + G PF +N +E+++KI KA + PS + P++ L+ +L + ++R+
Sbjct: 203 FVLLAGYLPFHDTNLMEMYRKIGKA--DFKCPS--WFAPEVKRLLCKMLDPNHETRI 255
>At3g01090 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 132 bits (332), Expect = 2e-30
Identities = 98/327 (29%), Positives = 144/327 (43%), Gaps = 50/327 (15%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + + +G GSF V G +AIK ++R EI IL+ HP
Sbjct: 18 NYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHP 77
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L + T +D YL+MEY G+L +I E
Sbjct: 78 HIIRLYEVIETPTDIYLVMEYVNSGELFDYI------------------------VEKGR 113
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L N+ QQ+ S +++ +VHRD+KP+NLLL D K
Sbjct: 114 LQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLL--------DSKCN---------- 155
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + + + +T CGSP Y APE+++ + Y + D+WS G +LY + C
Sbjct: 156 ---VKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLC 212
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N LF+KIK T+PS ++ P +LI +L DP R+ + +
Sbjct: 213 GTLPFDDENIPNLFKKIK--GGIYTLPS--HLSPGARDLIPRMLVVDPMKRVTIPEIRQH 268
Query: 319 EVVTEDLTRYEQSYEPDLESKSKDVAE 345
L RY PD ++K + E
Sbjct: 269 PWFQAHLPRYLAVPPPDTVQQAKKIDE 295
>YDL101c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 513
Score = 131 bits (330), Expect = 4e-30
Identities = 93/309 (30%), Positives = 149/309 (48%), Gaps = 38/309 (12%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+ Y + KE+G G +A+V + + + G+ +A+K E IL +++H
Sbjct: 198 DKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQH 257
Query: 79 PHIVGLIDC-----ERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPP 133
P+IV L+D ++ YL++E G+L F + + L+ K +F+
Sbjct: 258 PNIVNLLDSFVEPISKSQIQKYLVLEKIDDGEL--FERIVRKTCLRQDESKALFK----- 310
Query: 134 STEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELG 193
QL + LK+L +N++HRDIKP+N+LL + + + +LG
Sbjct: 311 -----------------QLLTGLKYLHEQNIIHRDIKPENILLN---ITRRENPSQVQLG 350
Query: 194 FVGIYNLPI-LKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTV 252
+ I +KIADFG A+F TLCG+P Y+APE+L + Y +K DLWS G +
Sbjct: 351 PWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVI 410
Query: 253 LYEMCCGRPPFKASNHL---ELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
LY CG PPF S+ L L ++I +A P I+ + +LI LL +PD R
Sbjct: 411 LYVCLCGFPPF--SDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDER 468
Query: 310 MGFTDFFNN 318
+ N+
Sbjct: 469 YNIDEALNH 477
>At3g29160 [T] KOG0583 Serine/threonine protein kinase
Length = 512
Score = 131 bits (329), Expect = 5e-30
Identities = 96/327 (29%), Positives = 144/327 (43%), Gaps = 50/327 (15%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K +G GSF V + G +AIK ++R EI IL+ HP
Sbjct: 19 NYKLGKTLGIGSFGKVKIAEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHP 78
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ + T+SD Y++MEY G+L +I E
Sbjct: 79 HIIRQYEVIETTSDIYVVMEYVKSGELFDYI------------------------VEKGR 114
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L N+ QQ+ S +++ +VHRD+KP+NLLL +
Sbjct: 115 LQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCN------------------ 156
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + + + +T CGSP Y APE+++ + Y + D+WS G +LY + C
Sbjct: 157 ---IKIADFGLSNVMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLC 213
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N LF+KIK T+PS+ E + +LI +L DP R+ + +
Sbjct: 214 GTLPFDDENIPNLFKKIK--GGIYTLPSHLSSEAR--DLIPRMLIVDPVKRITIPEIRQH 269
Query: 319 EVVTEDLTRYEQSYEPDLESKSKDVAE 345
L RY PD ++K + E
Sbjct: 270 RWFQTHLPRYLAVSPPDTVEQAKKINE 296
>YKL166c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 398
Score = 130 bits (327), Expect = 8e-30
Identities = 91/344 (26%), Positives = 161/344 (46%), Gaps = 62/344 (18%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
++ + + +G GSF V+ S +GR A+K + + E +L + HP
Sbjct: 87 DFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHP 146
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
I+ + + S +++M+Y G+L ++K + +P P +
Sbjct: 147 FIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKS--------------QRFPNPVAKF-- 190
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
Y ++ AL++L SK++++RD+KP+N+LL K H
Sbjct: 191 --------YAAEVCLALEYLHSKDIIYRDLKPENILL---------DKNGH--------- 224
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+KI DFGFA+++P+ + TLCG+P Y+APE+++ + YN D WS G ++YEM G
Sbjct: 225 ---IKITDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAG 279
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD----- 314
PF SN ++ ++ I N E+ P + P +L++ L+T D R+G
Sbjct: 280 YTPFYNSNTMKTYENI--LNAELKFPP--FFHPDAQDLLKKLITRDLSERLGNLQNGSED 335
Query: 315 -----FFNNEVVTEDLTRY-EQSYEPDLESKSKDVAESNMFVSE 352
+FN + + L RY E YEP ++ D ++ + + E
Sbjct: 336 VKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379
>At2g34180 [T] KOG0583 Serine/threonine protein kinase
Length = 502
Score = 130 bits (326), Expect = 1e-29
Identities = 86/296 (29%), Positives = 140/296 (47%), Gaps = 54/296 (18%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+ Y + K +G GSFA VY ++ G ++AIK + + EI+IL++++H
Sbjct: 55 DKYEIGKLLGHGSFAKVYLARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVRH 114
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV L++ T + Y++MEY G+L + + +
Sbjct: 115 PYIVHLLEVMATKTKIYIVMEYVRGGELYNTVARGR------------------------ 150
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
L Y QQL S++ F S+ + HRD+K +NLLL D K
Sbjct: 151 -LREGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLL--------DDK----------- 190
Query: 199 NLPILKIADFGF---ARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLY 254
+K++DFG + L + +T CG+P Y+APE+L + Y AKAD+WS G +L+
Sbjct: 191 --GNVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKADIWSCGVILF 248
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ G PF N L ++ KI K + P + P+L L+ +L +PD+R+
Sbjct: 249 VLMAGYLPFDDKNILVMYTKIYKG--QFKCPK--WFSPELARLVTRMLDTNPDTRI 300
>Hs20479818 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 514
Score = 129 bits (325), Expect = 1e-29
Identities = 99/411 (24%), Positives = 181/411 (43%), Gaps = 64/411 (15%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E Y+ + +GKGSF +V + AIK V++ E+ ILK +KH
Sbjct: 114 EIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLER-EVNILKSVKH 172
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
HI+ L T YL+ME C G+L + ++ H+ T
Sbjct: 173 EHIIHLEQVFETPKKMYLVMELCEDGELKEILDRK--------------GHFSENETRW- 217
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+Q L+SA+ +L + ++VHRD+K +N+++ + L+D N+ +
Sbjct: 218 ---------IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLN-------- 260
Query: 199 NLPILKIADFGFA--RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+K+ DFG A + + ++ + CG+P+YMAPE+++ Y+ + D+WS+G V+Y +
Sbjct: 261 ----IKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYML 316
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PPF AS+ +LF+ I+K I ++++ L+ DP R+ +
Sbjct: 317 LRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELL 376
Query: 317 NNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTS 376
+N+ +T +K V +N+ L+ + P +ENT+
Sbjct: 377 DNQWLT--------------GNKLSSVRPTNV---------LEMMKEWKNNPESVEENTT 413
Query: 377 VQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSYQSASQKRLKSSYND 427
+ + S +E+L + P S E+ +A +K+ ++ D
Sbjct: 414 EEK--NKPSTEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKD 462
>7293496 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 805
Score = 129 bits (325), Expect = 1e-29
Identities = 111/385 (28%), Positives = 174/385 (44%), Gaps = 65/385 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y+V +G+GSF VYK D + +AIK +S+ E I ++KHPH
Sbjct: 4 YAVSSMVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRR-ECDIQARLKHPH 62
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
++ +I+ + +D +++ E+ AL DL ++ N + + V H
Sbjct: 63 VIEMIESFESKTDLFVVTEF-ALMDLHRYLSY--NGAMGEEPARRVTGH----------- 108
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
L SAL +L S ++HRD+KPQN+LL K H
Sbjct: 109 -----------LVSALYYLHSNRILHRDLKPQNVLL---------DKNMHA--------- 139
Query: 201 PILKIADFGFARFLP-NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
K+ DFG AR + T + ++ G+PLYMAPE+L Q Y+ AD+WS+G + YE G
Sbjct: 140 ---KLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAG 196
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
+PPF AS+ L L + IK ++++ PS E + F ++GLL DP R+ +T +
Sbjct: 197 QPPFCASSILHLVKMIK--HEDVKWPSTLTSECRSF--LQGLLEKDPGLRISWTQLLCHP 252
Query: 320 VVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTSVQT 379
V + E++++ ES E VK KQ + P D + ++
Sbjct: 253 FVEGRIF--------IAETQAEAAKESPFTNPEAKVKSSKQSD-----PEVGDLDEALAA 299
Query: 380 GVRRTSGKERLATNHPPHQQIHPED 404
S +E L T+ I P D
Sbjct: 300 LDFGESRQENLTTSRDSINAIAPSD 324
>At5g01810 [T] KOG0583 Serine/threonine protein kinase
Length = 421
Score = 129 bits (324), Expect = 2e-29
Identities = 97/334 (29%), Positives = 156/334 (46%), Gaps = 59/334 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y V K +G+G+FA VY L+ G ++AIK + + EI+ ++ ++HP+
Sbjct: 12 YEVGKFLGQGTFAKVYHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPN 71
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T S Y +ME+ G+L + K L
Sbjct: 72 IVELHEVMATKSKIYFVMEHVKGGELFNKVSTGK-------------------------L 106
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Y QQL A+ F S+ + HRD+KP+NLLL E G
Sbjct: 107 REDVARKYFQQLVRAVDFCHSRGVCHRDLKPENLLL-------------DEHG------- 146
Query: 201 PILKIADFGFARFLPN---TSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEM 256
LKI+DFG + + L T CG+P Y+APE+++ Y+ KAD+WS G +L+ +
Sbjct: 147 -NLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSCGVILFVL 205
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGF---- 312
G PF+ SN +EL++KI KA E+ P+ ++ P L++ +L +P++R+
Sbjct: 206 LAGYLPFRDSNLMELYKKIGKA--EVKFPN--WLAPGAKRLLKRILDPNPNTRVSTEKIM 261
Query: 313 -TDFFNNEVVTEDLTRYEQSYEPDLESKSKDVAE 345
+ +F + E E+ E D E++ AE
Sbjct: 262 KSSWFRKGLQEEVKESVEEETEVDAEAEGNASAE 295
>At5g01820 [T] KOG0583 Serine/threonine protein kinase
Length = 442
Score = 129 bits (323), Expect = 2e-29
Identities = 97/317 (30%), Positives = 145/317 (45%), Gaps = 62/317 (19%)
Query: 14 IRLPTEN--------YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXX 65
+ P EN Y V K +G G+FA VY G S G+++AIK VS+
Sbjct: 7 VEFPPENRRGQLFGKYEVGKLVGCGAFAKVYHGRSTATGQSVAIKVVSKQRLQKGGLNGN 66
Query: 66 XXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKT 125
EIAI+ +++HP IV L + T S + +ME+ G+L F K K +
Sbjct: 67 IQREIAIMHRLRHPSIVRLFEVLATKSKIFFVMEFAKGGEL--FAKVSKGRFCED----- 119
Query: 126 VFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYND 185
L Y QQL SA+ + S+ + HRD+KP+NLLL L
Sbjct: 120 ------------------LSRRYFQQLISAVGYCHSRGIFHRDLKPENLLLDEKL----- 156
Query: 186 PKTFHELGFVGIYNLPILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN- 241
LKI+DFG + + L TLCG+P Y+APE+L + Y+
Sbjct: 157 ----------------DLKISDFGLSALTDQIRPDGLLHTLCGTPAYVAPEVLAKKGYDG 200
Query: 242 AKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGL 301
AK D+WS G +L+ + G PF N + +++KI K E +P + P L L+ L
Sbjct: 201 AKIDIWSCGIILFVLNAGYLPFNDHNLMVMYRKIYKG--EFRIPK--WTSPDLRRLLTRL 256
Query: 302 LTFDPDSRMGFTDFFNN 318
L +P +R+ + ++
Sbjct: 257 LDTNPQTRITIEEIIHD 273
>At5g25110 [T] KOG0583 Serine/threonine protein kinase
Length = 460
Score = 128 bits (321), Expect = 4e-29
Identities = 90/301 (29%), Positives = 141/301 (45%), Gaps = 54/301 (17%)
Query: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAIL 73
+R+ Y + + +GKG+F VY G + G ++AIK +++ EI+I+
Sbjct: 8 LRVLFAKYEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIM 67
Query: 74 KKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPP 133
+ ++HP+IV L + T + + IMEY G+L I K K
Sbjct: 68 RLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGK------------------- 108
Query: 134 STEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELG 193
L Y QQL SA+ F S+ + HRD+KP+NL L+D N
Sbjct: 109 ------LKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENL-----LVDENGD------- 150
Query: 194 FVGIYNLPILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSV 249
LK++DFG + + L T CG+P Y+APE+L + Y+ AK D+WS
Sbjct: 151 ---------LKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDGAKGDIWSC 201
Query: 250 GTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G +LY + G PF+ N +++++KI K+ E + P+ LI LL DP+ R
Sbjct: 202 GIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPP----WFSPESKRLISKLLVVDPNKR 257
Query: 310 M 310
+
Sbjct: 258 I 258
>At5g10930 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 128 bits (321), Expect = 4e-29
Identities = 93/295 (31%), Positives = 140/295 (46%), Gaps = 55/295 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV-EIAILKKIKHP 79
Y + + +GKG+FA VY G + G +AIK +++ EI+I+K ++HP
Sbjct: 12 YEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T + + +ME+ G+L I K K
Sbjct: 72 NIVELKEVMATKTKIFFVMEFVKGGELFCKISKGK------------------------- 106
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L+ Y QQL SA+ + S+ + HRD+KP+NLLL D N
Sbjct: 107 LHEDAARRYFQQLISAVDYCHSRGVSHRDLKPENLLL-----DENGD------------- 148
Query: 200 LPILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYE 255
LKI+DFG + + L T CG+P Y+APE+L + Y+ AKAD+WS G VLY
Sbjct: 149 ---LKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYDGAKADIWSCGVVLYV 205
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ G PF+ N + +++KI +A+ E + P+ LI LL DPD R+
Sbjct: 206 LLAGCLPFQDENLMNMYRKIFRADFEFPP----WFSPEARRLISKLLVVDPDRRI 256
>At1g30270 [T] KOG0583 Serine/threonine protein kinase
Length = 480
Score = 128 bits (321), Expect = 4e-29
Identities = 92/302 (30%), Positives = 146/302 (47%), Gaps = 53/302 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + +G+G+FA V ++ +G N+AIK + + EI+ +K IKHP+
Sbjct: 31 YELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPN 90
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
++ + + + + Y ++E+ G+L F K N LK +
Sbjct: 91 VIRMFEVMASKTKIYFVLEFVTGGEL--FDKISSNGRLKEDEAR---------------- 132
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
Y QQL +A+ + S+ + HRD+KP+NL LLD N
Sbjct: 133 ------KYFQQLINAVDYCHSRGVYHRDLKPENL-----LLDANG--------------- 166
Query: 201 PILKIADFGFARFLP--NTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEMC 257
LK++DFG + LP L T CG+P Y+APE++N + Y+ AKADLWS G +L+ +
Sbjct: 167 -ALKVSDFGLSA-LPQQEDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLM 224
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G PF+ SN L++KI KA E T P + LI+ +L +P +R+ F +
Sbjct: 225 AGYLPFEDSNLTSLYKKIFKA--EFTCPP--WFSASAKKLIKRILDPNPATRITFAEVIE 280
Query: 318 NE 319
NE
Sbjct: 281 NE 282
>At1g50230 [R] KOG0597 Serine-threonine protein kinase FUSED
Length = 269
Score = 127 bits (320), Expect = 5e-29
Identities = 88/293 (30%), Positives = 144/293 (49%), Gaps = 52/293 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E+Y V + +G+GSF VYKG G+ +A+K + + EI IL+K+KH
Sbjct: 4 EDYHVIELVGEGSFGRVYKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQ-EIEILRKLKH 62
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
+I+ ++D + +F ++ E+ A G+L ++ K L P +
Sbjct: 63 ENIIEMLDSFENAREFCVVTEF-AQGELFEILEDDKCL----------------PEEQ-- 103
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
V +QL AL +L S ++HRD+KPQN+L+
Sbjct: 104 ------VQAIAKQLVKALDYLHSNRIIHRDMKPQNILIGAG------------------- 138
Query: 199 NLPILKIADFGFARFL-PNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
++K+ DFGFAR + NT + ++ G+PLYMAPE++ Q Y+ DLWS+G +LYE+
Sbjct: 139 --SVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVKEQPYDRTVDLWSLGVILYELY 196
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G+PPF ++ L + I K + + Y E + ++GLL +P SR+
Sbjct: 197 VGQPPFYTNSVYALIRHIVKDPVKYPDEMSTYFE----SFLKGLLNKEPHSRL 245
>YJL164c [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 397
Score = 127 bits (319), Expect = 7e-29
Identities = 94/345 (27%), Positives = 162/345 (46%), Gaps = 62/345 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+N+ + + +G GSF V+ S +GR A+K + + E +L + H
Sbjct: 85 KNFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTH 144
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P I+ + + + ++IM+Y G+L ++K + +P P +
Sbjct: 145 PFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKS--------------QRFPNPVAKF- 189
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
Y ++ AL++L SK++++RD+KP+N+LL K H
Sbjct: 190 ---------YAAEVCLALEYLHSKDIIYRDLKPENILL---------DKNGH-------- 223
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
+KI DFGFA+++P+ + TLCG+P Y+APE+++ + YN D WS G ++YEM
Sbjct: 224 ----IKITDFGFAKYVPDVTY--TLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLA 277
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG----FTD 314
G PF SN ++ ++KI N E+ P + + +L+ L+T D R+G T+
Sbjct: 278 GYTPFYDSNTMKTYEKI--LNAELRFPP--FFNEDVKDLLSRLITRDLSQRLGNLQNGTE 333
Query: 315 FFNN-----EVVTEDL--TRYEQSYEPDLESKSKDVAESNMFVSE 352
N EVV E L E YEP ++ D ++ + + E
Sbjct: 334 DVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEE 378
>SPCC74.03c [T] KOG0583 Serine/threonine protein kinase
Length = 576
Score = 127 bits (319), Expect = 7e-29
Identities = 100/353 (28%), Positives = 161/353 (45%), Gaps = 58/353 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + +G+GSF V + + +A+K +SR EI+ LK ++HPH
Sbjct: 34 YIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ L D T +D +++EY A G+L +I ++K + TE G
Sbjct: 94 IIKLYDVITTPTDIVMVIEY-AGGELFDYIVEKKRM------------------TEDEGR 134
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ QQ+ A+++ +VHRD+KP+NLLL L
Sbjct: 135 ------RFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNL-------------------- 168
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCCG 259
+KIADFG + + + + +T CGSP Y APE++N + Y + D+WS G VLY M G
Sbjct: 169 -NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVG 227
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
R PF LF KK N + V + ++ P +LIR ++ DP R+ + +
Sbjct: 228 RLPFDDEFIPNLF---KKVNSCVYVMPD-FLSPGAQSLIRRMIVADPMQRITIQEIRRDP 283
Query: 320 VVTEDLTRYEQSYE------PDLESKSKDVAESNMFVSEYLVKPLKQQESAHI 366
+L Y + E D SK + E+ F +Y+V+ L+ E+ +
Sbjct: 284 WFNVNLPDYLRPMEEVQGSYADSRIVSK-LGEAMGFSEDYIVEALRSDENNEV 335
>7299437 [R] KOG0586 Serine/threonine protein kinase
Length = 604
Score = 127 bits (318), Expect = 9e-29
Identities = 89/290 (30%), Positives = 136/290 (46%), Gaps = 51/290 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K +GKG+FA V + L GR +AIK + ++ E+ I+KK+ HP+
Sbjct: 63 YKIIKTLGKGNFAKVKLAIHLPTGREVAIKLIDKTALNTIARQKLYR-EVNIMKKLNHPN 121
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L+ + YL+MEY + G+L ++ K + +
Sbjct: 122 IVRLLQVIESERTLYLVMEYVSGGELFNYLVKNGRMRERDA------------------- 162
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
RVL +QL SA+++ SK++VHRD+K +NLLL +
Sbjct: 163 -RVL----FRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMK------------------- 198
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
LKIADFGF+ + ET CGSP Y APE+ +KY+ + D WS+G VLY + G
Sbjct: 199 --LKIADFGFSTTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSG 256
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
PF +N EL ++ + + Y+ + +LIR L +P R
Sbjct: 257 SLPFDGTNLKELRDRVLRGKYRVPY----YVSIECESLIRKFLVLNPTQR 302
>YDR477w [T] KOG0583 Serine/threonine protein kinase
Length = 633
Score = 126 bits (317), Expect = 1e-28
Identities = 85/329 (25%), Positives = 150/329 (44%), Gaps = 53/329 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K +G+GSF V G+ +A+K +++ EI+ L+ ++HP
Sbjct: 54 NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHP 113
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L D ++ + +++EY + +++ K
Sbjct: 114 HIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDK------------------------- 148
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
++ + QQ+ SA+++ +VHRD+KP+NLLL L
Sbjct: 149 MSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN------------------ 190
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + + + + +T CGSP Y APE+++ + Y + D+WS G +LY M C
Sbjct: 191 ---VKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLC 247
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
R PF + LF+ I +N T+P ++ P LI+ +L +P +R+ + +
Sbjct: 248 RRLPFDDESIPVLFKNI--SNGVYTLPK--FLSPGAAGLIKRMLIVNPLNRISIHEIMQD 303
Query: 319 EVVTEDLTRYEQSYEPDLESKSKDVAESN 347
+ DL Y PDL+ ++ E+N
Sbjct: 304 DWFKVDLPEY--LLPPDLKPHPEEENENN 330
>CE28643 [T] KOG0583 Serine/threonine protein kinase
Length = 564
Score = 126 bits (317), Expect = 1e-28
Identities = 88/310 (28%), Positives = 140/310 (44%), Gaps = 50/310 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+Y +++ +G G+F V G+ +A+K ++R EI L +HP
Sbjct: 24 HYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHP 83
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L T SD ++IME+ + G+L +I +KH +KT
Sbjct: 84 HIIRLYQVISTPSDIFMIMEHVSGGELFDYI-------VKHGRLKTAEAR---------- 126
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ QQ+ S + + +VHRD+KP+NLLL + N+
Sbjct: 127 -------RFFQQIISGVDYCHRHMVVHRDLKPENLLLD----EQNN-------------- 161
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + + + T CGSP Y APE+++ + Y + D+WS G +LY + C
Sbjct: 162 ---VKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLC 218
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF + LF+KIK P+ ++E + NL+ +L DP R D +
Sbjct: 219 GTLPFDDEHVPSLFRKIKSG----VFPTPDFLERPIVNLLHHMLCVDPMKRATIKDVIAH 274
Query: 319 EVVTEDLTRY 328
E +DL Y
Sbjct: 275 EWFQKDLPNY 284
>CE07458 [T] KOG0583 Serine/threonine protein kinase
Length = 562
Score = 126 bits (317), Expect = 1e-28
Identities = 88/310 (28%), Positives = 140/310 (44%), Gaps = 50/310 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+Y +++ +G G+F V G+ +A+K ++R EI L +HP
Sbjct: 24 HYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHP 83
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L T SD ++IME+ + G+L +I +KH +KT
Sbjct: 84 HIIRLYQVISTPSDIFMIMEHVSGGELFDYI-------VKHGRLKTAEAR---------- 126
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ QQ+ S + + +VHRD+KP+NLLL + N+
Sbjct: 127 -------RFFQQIISGVDYCHRHMVVHRDLKPENLLLD----EQNN-------------- 161
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + + + T CGSP Y APE+++ + Y + D+WS G +LY + C
Sbjct: 162 ---VKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLC 218
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF + LF+KIK P+ ++E + NL+ +L DP R D +
Sbjct: 219 GTLPFDDEHVPSLFRKIKSG----VFPTPDFLERPIVNLLHHMLCVDPMKRATIKDVIAH 274
Query: 319 EVVTEDLTRY 328
E +DL Y
Sbjct: 275 EWFQKDLPNY 284
>Hs5730055 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 685
Score = 126 bits (316), Expect = 2e-28
Identities = 92/334 (27%), Positives = 151/334 (44%), Gaps = 59/334 (17%)
Query: 10 VAKAIRLPT--ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXX 67
+++ I PT + Y K +GKG FA Y+ L + + A K + S
Sbjct: 69 ISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 128
Query: 68 VEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVF 127
EI + + + H H+V + Y+++EYC+ + +K RK VL P ++
Sbjct: 129 KEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARK--VLTEPEVRY-- 184
Query: 128 EHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPK 187
YL+Q+ S LK+L + ++HRD+K
Sbjct: 185 --------------------YLRQIVSGLKYLHEQEILHRDLK----------------- 207
Query: 188 TFHELGFVGIYNLPILKIADFGFA-RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADL 246
LG I LK+ DFG A R P T+CG+P Y++PE+LN Q + ++D+
Sbjct: 208 ----LGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDI 263
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
W++G V+Y M GRPPF+ +N E ++ I++A T+PS+ K +LI +L+ +P
Sbjct: 264 WALGCVMYTMLLGRPPFETTNLKETYRCIREA--RYTMPSSLLAPAK--HLIASMLSKNP 319
Query: 307 DSRMGFTDFFNNEVVTEDLTRYEQSYEPDLESKS 340
+ R D ++ + Q + PD S S
Sbjct: 320 EDRPSLDDIIRHDF-------FLQGFTPDRLSSS 346
>Hs22043888 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 765
Score = 126 bits (316), Expect = 2e-28
Identities = 94/341 (27%), Positives = 157/341 (45%), Gaps = 62/341 (18%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSX----------------XXXXXX 62
E Y + K IG G+FAVV + + G+ A+K + ++
Sbjct: 196 EKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKQCAPSNTDTSCEAIVGST 255
Query: 63 XXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPL 122
E++IL+++KHP+I+ L++ T+++ +L+ME GDL I
Sbjct: 256 EHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKY------ 309
Query: 123 IKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLD 182
TE +G +V N L++AL++L ++VHRDIKP+NLL+C +
Sbjct: 310 ------------TERDG--SAMVYN----LANALRYLHGLSIVHRDIKPENLLVC----E 347
Query: 183 YNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA 242
Y D LK+ DFG A + T+CG+P Y+APEI+ Y
Sbjct: 348 YPD-------------GTKSLKLGDFGLATVVEGPLY--TVCGTPTYVAPEIIAETGYGL 392
Query: 243 KADLWSVGTVLYEMCCGRPPFKASNHL--ELFQKIKKANDEITVPSNCYIEPKLFNLIRG 300
K D+W+ G + Y + CG PPF++ N+L +LF +I E P I LI
Sbjct: 393 KVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQ 452
Query: 301 LLTFDPDSRMGFTDFFNNEVVTEDLTRYEQSYEPDLESKSK 341
+L + ++R ++ V++D ++ E + + ++ K K
Sbjct: 453 MLQVNVEARCTAGQILSHPWVSDDASQ-ENNMQAEVTGKLK 492
>7303211 [T] KOG4717 Serine/threonine protein kinase
Length = 860
Score = 125 bits (315), Expect = 2e-28
Identities = 90/291 (30%), Positives = 138/291 (46%), Gaps = 51/291 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +E+ +G G FAVV + G +A+K V ++ E+ +K ++HP+
Sbjct: 20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSKAHLFQ-EVRCMKLVQHPN 78
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V L + T + YL++E GDL +I K + GL
Sbjct: 79 VVRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDS-----------------------GL 115
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ L Y +Q+ A+ + ++VHRD+KP+N++ F +LG V
Sbjct: 116 SEELARKYFRQILRAITYCHQLHVVHRDLKPENVVF------------FEKLGLV----- 158
Query: 201 PILKIADFGFA-RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA-DLWSVGTVLYEMCC 258
K+ DFGF+ +FLP L ET CGS Y APEIL Y+A A D+WS+G +LY + C
Sbjct: 159 ---KLTDFGFSNKFLPGQKL-ETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVC 214
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G+ PF+ +N E I + TVPS ++ +LI +L DP R
Sbjct: 215 GQAPFEKANDSETLTMIMDC--KYTVPS--HVSTDCRDLIASMLVRDPKKR 261
>Hs4758128_2 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 385
Score = 125 bits (315), Expect = 2e-28
Identities = 96/323 (29%), Positives = 143/323 (43%), Gaps = 50/323 (15%)
Query: 7 DKVVAKAIRLP---TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXX 63
++V + ++P TE Y V + IG G+FAVV + + R A+K + +S
Sbjct: 29 EEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM 88
Query: 64 XXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLI 123
E++IL+++KHP+IV LI+ ++ YL+ME GDL I
Sbjct: 89 IQN--EVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAI------------- 133
Query: 124 KTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDY 183
T N L L+SA+K+L S N+VHRDIKP+NLL+
Sbjct: 134 -----------TSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYE----- 177
Query: 184 NDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAK 243
H+ G LK+ DFG A + T+CG+P Y+APEI+ Y K
Sbjct: 178 ------HQDGSKS------LKLGDFGLATIVDGP--LYTVCGTPTYVAPEIIAETGYGLK 223
Query: 244 ADLWSVGTVLYEMCCGRPPFKASNHLE--LFQKIKKANDEITVPSNCYIEPKLFNLIRGL 301
D+W+ G + Y + CG PPF+ S + LF +I + P + LI +
Sbjct: 224 VDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMM 283
Query: 302 LTFDPDSRMGFTDFFNNEVVTED 324
L D D R + V +D
Sbjct: 284 LLVDVDQRFSAVQVLEHPWVNDD 306
>SPAC23A1.06c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 504
Score = 125 bits (314), Expect = 3e-28
Identities = 95/331 (28%), Positives = 151/331 (44%), Gaps = 39/331 (11%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E Y + + +G G+F+ VYK S+ ++A+K + R E+ I++++KH
Sbjct: 63 EKYQLIENLGDGAFSQVYKAYSIDRKEHVAVKVI-RKYEMNKKQRQGVFKEVNIMRRVKH 121
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
++V L D T ++L+ME G+L H ++ +
Sbjct: 122 KNVVNLFDFVETEDFYHLVMELAEGGELF------------HQIVNFTY----------- 158
Query: 139 GLNRVLVVNYLQQLSSALKFLRSK-NLVHRDIKPQNLLL-----------CTPLLDYNDP 186
+ L + + Q++ A+K L +VHRDIKP+NLL P L+ N
Sbjct: 159 -FSENLARHIIIQVAEAVKHLHDVCGIVHRDIKPENLLFQPIEYLPSQNYTPPSLEPNKL 217
Query: 187 KTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADL 246
L +G + + IADFGF++ + N+ A T CG+ Y APEI+N + Y+ D+
Sbjct: 218 DEGMFLEGIGAGGIGRILIADFGFSKVVWNSKTA-TPCGTVGYAAPEIVNDELYSKNVDM 276
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
W++G VL+ M CG PPF N +L K+ E P I +LI LLT DP
Sbjct: 277 WAMGCVLHTMLCGFPPFFDENIKDLASKVVNGEFEFLSPWWDDISDSAKDLITHLLTVDP 336
Query: 307 DSRMGFTDFFNNEVVTEDLTRYEQ-SYEPDL 336
R FF + + + E +Y+P L
Sbjct: 337 RERYDIHQFFQHPWIKGESKMPENFTYKPKL 367
>At4g18700 [T] KOG0583 Serine/threonine protein kinase
Length = 489
Score = 125 bits (314), Expect = 3e-28
Identities = 86/302 (28%), Positives = 139/302 (45%), Gaps = 54/302 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K +G G+FA VY +++ ++AIK + + EI+IL++++HP+
Sbjct: 26 YEMGKLLGHGTFAKVYLARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPN 85
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T + Y +MEY G+L + K + L
Sbjct: 86 IVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGR-------------------------L 120
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Y QQL SA+ F ++ + HRD+KP+NL LLD N
Sbjct: 121 KEEVARKYFQQLISAVTFCHARGVYHRDLKPENL-----LLDENGN-------------- 161
Query: 201 PILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEM 256
LK++DFG + + L T CG+P Y+APE+L + Y+ AK D+WS G +L+ +
Sbjct: 162 --LKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDAAKVDIWSCGVILFVL 219
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PF N + +++KI + E P + +L L+ LL +P+ R F +
Sbjct: 220 MAGYLPFHDRNVMAMYKKIYRG--EFRCPR--WFSTELTRLLSKLLETNPEKRFTFPEIM 275
Query: 317 NN 318
N
Sbjct: 276 EN 277
>Hs19923407 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 313
Score = 125 bits (313), Expect = 3e-28
Identities = 88/303 (29%), Positives = 142/303 (46%), Gaps = 52/303 (17%)
Query: 13 AIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAI 72
+ R ++ +EK+IG+G F+ VYK L D + +A+K V EI +
Sbjct: 37 SFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGL 96
Query: 73 LKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIK---KRKNLVLKHPLIKTVFEH 129
LK++ HP+I+ +D ++ +++E GDL+ IK K+K L+ + + K
Sbjct: 97 LKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWK----- 151
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTF 189
Y QL SA++ + S+ ++HRDIKP N+ +
Sbjct: 152 ------------------YFVQLCSAVEHMHSRRVMHRDIKPANVFITAT---------- 183
Query: 190 HELGFVGIYNLPILKIADFGFARFLPN-TSLAETLCGSPLYMAPEILNYQKYNAKADLWS 248
++K+ D G RF + T+ A +L G+P YM+PE ++ YN K+D+WS
Sbjct: 184 -----------GVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWS 232
Query: 249 VGTVLYEMCCGRPPFKAS--NHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
+G +LYEM + PF N L QKI++ D +P Y E KL L+ + DP
Sbjct: 233 LGCLLYEMAALQSPFYGDKMNLFSLCQKIEQC-DYPPLPGEHYSE-KLRELVSMCICPDP 290
Query: 307 DSR 309
R
Sbjct: 291 HQR 293
>Hs21361643 [T] KOG4717 Serine/threonine protein kinase
Length = 765
Score = 124 bits (312), Expect = 5e-28
Identities = 91/300 (30%), Positives = 141/300 (46%), Gaps = 51/300 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y ++K +G+G FAVV + G +A+K + ++ E+ +K ++HP+
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQ-EVRCMKLVQHPN 74
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T + YLI+E GD+ +I K + GL
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEE-----------------------GL 111
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
N L Y Q+ A+ + ++VHRD+KP+N++ F + G V
Sbjct: 112 NEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVF------------FEKQGLV----- 154
Query: 201 PILKIADFGFA-RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA-DLWSVGTVLYEMCC 258
K+ DFGF+ +F P L T CGS Y APEIL +Y+A A D+WS+G +L+ + C
Sbjct: 155 ---KLTDFGFSNKFQPGKKLT-TSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVC 210
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G+PPF+ +N E I + TVPS+ E K +LI +L DP R + N+
Sbjct: 211 GQPPFQEANDSETLTMIMDC--KYTVPSHVSKECK--DLITRMLQRDPKRRASLEEIENH 266
>7302570 [R] KOG0586 Serine/threonine protein kinase
Length = 702
Score = 124 bits (312), Expect = 5e-28
Identities = 97/328 (29%), Positives = 145/328 (43%), Gaps = 52/328 (15%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +EK IGKG+FAVV ++ +AIK + ++ EIAILK ++HPH
Sbjct: 41 YELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFR-EIAILKSLRHPH 99
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I L + + S YL+ EY G++ F N +K P VF
Sbjct: 100 ITRLYEVMESQSMIYLVTEYAPNGEI--FDHLVANGRMKEPEAARVF------------- 144
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
QL SA+ + + +VHRD+K +N+LL D N
Sbjct: 145 ---------TQLVSAVHYCHRRGVVHRDLKAENVLLDK---DMN---------------- 176
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+K+ADFGF+ + +T CGSP Y APE+ +Y+ K+D+WS+G VLY + CG
Sbjct: 177 --IKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCG 234
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PF LEL ++ I ++ + LIR +L +PD R +
Sbjct: 235 ALPFDGKTILELKSRVVLGKFRIPF----FMSQECEQLIRNMLVVEPDRRYTIKQIIKHR 290
Query: 320 VVTE-DLTRYEQSYEPDLESKSKDVAES 346
++E EQ D+ S V++S
Sbjct: 291 WLSEWQSEMQEQERFGDMSPGSGTVSKS 318
>Hs5453964 [T] KOG0583 Serine/threonine protein kinase
Length = 550
Score = 124 bits (310), Expect = 8e-28
Identities = 90/329 (27%), Positives = 139/329 (41%), Gaps = 50/329 (15%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R+ +Y + +G G+F V G G +A+K ++R EI LK
Sbjct: 12 RVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLK 71
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+HPHI+ L T SD +++MEY + G+L +I K L K
Sbjct: 72 LFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESR------------ 119
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
QQ+ S + + +VHRD+KP+N+LL +
Sbjct: 120 ------------RLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHM-------------- 153
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVL 253
KIADFG + + + T CGSP Y APE+++ + Y + D+WS G +L
Sbjct: 154 -------NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVIL 206
Query: 254 YEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFT 313
Y + CG PF + LF+KI + P Y+ P + +L++ +L DP R
Sbjct: 207 YALLCGTLPFDDDHVPTLFKKI--CDGIFYTPQ--YLNPSVISLLKHMLQVDPMKRASIK 262
Query: 314 DFFNNEVVTEDLTRYEQSYEPDLESKSKD 342
D +E +DL +Y +P S D
Sbjct: 263 DIREHEWFKQDLPKYLFPEDPSYSSTMID 291
>Hs4502553 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 124 bits (310), Expect = 8e-28
Identities = 93/326 (28%), Positives = 143/326 (43%), Gaps = 44/326 (13%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +G G+F+ V R + +AIK +++ EIA+L KIKHP+
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMEN--EIAVLHKIKHPN 77
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L D + YLIM+ + G+L F K + + +F
Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGEL-FDRIVEKGFYTERDASRLIF------------- 123
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
Q+ A+K+L +VHRD+KP+NLL + LD D K
Sbjct: 124 ----------QVLDAVKYLHDLGIVHRDLKPENLLYYS--LD-EDSK------------- 157
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGR 260
+ I+DFG ++ S+ T CG+P Y+APE+L + Y+ D WS+G + Y + CG
Sbjct: 158 --IMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGY 215
Query: 261 PPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEV 320
PPF N +LF++I KA E P I + IR L+ DP+ R +
Sbjct: 216 PPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
Query: 321 VTEDLTRYEQSYEPDLESKSKDVAES 346
+ D + ++ E K+ A+S
Sbjct: 276 IAGDTALDKNIHQSVSEQIKKNFAKS 301
>YMR001c [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 705
Score = 123 bits (309), Expect = 1e-27
Identities = 113/437 (25%), Positives = 193/437 (43%), Gaps = 79/437 (18%)
Query: 8 KVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXX 67
K I+ ++Y +G+G FA ++ + G A K V+++
Sbjct: 69 KTPPSLIKTRGKDYHRGHFLGEGGFARCFQ-IKDDSGEIFAAKTVAKASIKSEKTRKKLL 127
Query: 68 VEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVF 127
EI I K + HP+IV IDC S+ Y+++E C G L +K+RK VL P ++
Sbjct: 128 SEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRK--VLTEPEVRF-- 183
Query: 128 EHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPK 187
+ Q+ A+K++ S+ ++HRD+K N+
Sbjct: 184 --------------------FTTQICGAIKYMHSRRVIHRDLKLGNIF------------ 211
Query: 188 TFHELGFVGIYNLPILKIADFGFARFLPNTSLAE-TLCGSPLYMAPEIL--NYQKYNAKA 244
F YN LKI DFG A L N S + T+CG+P Y+APE+L + ++ +
Sbjct: 212 ------FDSNYN---LKIGDFGLAAVLANESERKYTICGTPNYIAPEVLMGKHSGHSFEV 262
Query: 245 DLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTF 304
D+WS+G +LY + G+PPF+A + ++++IK + + P + I + LIR +L+
Sbjct: 263 DIWSLGVMLYALLIGKPPFQARDVNTIYERIKCR--DFSFPRDKPISDEGKILIRDILSL 320
Query: 305 DPDSRMGFTDFFNNEVVTEDLTRYEQSYEPDLES-------KSKDVAESNMFVS--EYLV 355
DP R T+ D + ++ P + S +D+ E V+ + +
Sbjct: 321 DPIERPSLTEIM-------DYVWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCME 373
Query: 356 KP--LKQQESAHIPPTQTDENTSVQTGVRRTSGKERLATNHP--PHQQIHPEDNSQNPEQ 411
K L+ S I + D +S+++ + + E N P PH + P Q ++
Sbjct: 374 KSLLLESMSSDKIQRQKRDYISSIKSSIDKL---EEYHQNRPFLPH-SLSPGGTKQKYKE 429
Query: 412 SYQSASQKRLKSSYNDL 428
+Q+RL NDL
Sbjct: 430 VVDIEAQRRL----NDL 442
>Hs14196445 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 476
Score = 123 bits (308), Expect = 1e-27
Identities = 86/283 (30%), Positives = 131/283 (45%), Gaps = 46/283 (16%)
Query: 27 IGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGLID 86
+G G+F+ V+ G+ A+K + +S EIA+LKKIKH +IV L D
Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLEN---EIAVLKKIKHENIVTLED 85
Query: 87 CERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLVV 146
+++ +YL+M+ + G+L I +R K +
Sbjct: 86 IYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASL----------------------- 122
Query: 147 NYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKIA 206
+QQ+ SA+K+L +VHRD+KP+NLL TP + N + I
Sbjct: 123 -VIQQVLSAVKYLHENGIVHRDLKPENLLYLTP--EENSK----------------IMIT 163
Query: 207 DFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKAS 266
DFG ++ N + T CG+P Y+APE+L + Y+ D WS+G + Y + CG PPF
Sbjct: 164 DFGLSKMEQN-GIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEE 222
Query: 267 NHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
+LF+KIK+ E P I + I LL DP+ R
Sbjct: 223 TESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNER 265
>7290150 [T] KOG0583 Serine/threonine protein kinase
Length = 582
Score = 123 bits (308), Expect = 1e-27
Identities = 90/310 (29%), Positives = 135/310 (43%), Gaps = 50/310 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
+Y + +G G+F V G +A+K ++R EI LK +HP
Sbjct: 27 HYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHP 86
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L T SD ++IMEY + G+L +I K H
Sbjct: 87 HIIKLYQVISTPSDIFMIMEYVSGGELFDYIVK------------------------HGK 122
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L + QQ+ S + + +VHRD+KP+NL LLD+N H
Sbjct: 123 LQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENL-----LLDHN----MH--------- 164
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFG + + + T CGSP Y APE+++ + Y + D+WS G +LY + C
Sbjct: 165 ---VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLC 221
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF + LF+KIK P Y+ ++ NL+ +L DP R + +
Sbjct: 222 GTLPFDDEHVPTLFRKIKSG----IFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKH 277
Query: 319 EVVTEDLTRY 328
E +DL Y
Sbjct: 278 EWFQKDLPAY 287
>SPAC23C11.16 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 683
Score = 122 bits (307), Expect = 2e-27
Identities = 94/314 (29%), Positives = 147/314 (45%), Gaps = 58/314 (18%)
Query: 27 IGKGSFAVVYKGLSLRD--GRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGL 84
IG+G FA ++ ++D G A K +++ EI + + + HP+IVG
Sbjct: 47 IGEGGFARCFR---VKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGF 103
Query: 85 IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVL 144
IDC S++ YLI+E C L ++KRK L P ++ +
Sbjct: 104 IDCFEDSTNIYLILELCEHKSLMELLRKRKQLT--EPEVRYL------------------ 143
Query: 145 VVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILK 204
+ Q+ ALK++ K ++HRD+K N++L + N+ +K
Sbjct: 144 ----MMQILGALKYMHKKRVIHRDLKLGNIMLD----ESNN-----------------VK 178
Query: 205 IADFGFARFLPNTSLAE-TLCGSPLYMAPEILNYQK--YNAKADLWSVGTVLYEMCCGRP 261
I DFG A L + + T+CG+P Y+APEIL K ++ + DLWS G V+Y + G+P
Sbjct: 179 IGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKP 238
Query: 262 PFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEVV 321
PF+ +++KIK + + PSN I + +LI LLT DP R D ++E
Sbjct: 239 PFQDKEVKTIYRKIKA--NSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIVDHEFF 296
Query: 322 TEDLTRYEQSYEPD 335
T Y S PD
Sbjct: 297 H---TGYMASTLPD 307
>Hs4505373 [V] KOG1826 Ras GTPase activating protein RasGAP/neurofibromin
Length = 445
Score = 122 bits (307), Expect = 2e-27
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 64/389 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E+Y V IG GS+ K DG+ + K + E+ +L+++KH
Sbjct: 6 EDYEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVS-EVNLLRELKH 64
Query: 79 PHIVGLID--CERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTE 136
P+IV D +RT++ Y++MEYC GDL I K + E
Sbjct: 65 PNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKG--------------------TKE 104
Query: 137 HNGLNRVLVVNYLQQLSSALKFLRSKN-----LVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
L+ V+ + QL+ ALK ++ ++HRD+KP N+ L
Sbjct: 105 RQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLD-------------- 150
Query: 192 LGFVGIYNLPILKIADFGFARFLPN-TSLAETLCGSPLYMAPEILNYQKYNAKADLWSVG 250
G N+ K+ DFG AR L + TS A+T G+P YM+PE +N YN K+D+WS+G
Sbjct: 151 ----GKQNV---KLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLG 203
Query: 251 TVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+LYE+C PPF A + EL KI++ +P +L +I +L R
Sbjct: 204 CLLYELCALMPPFTAFSQKELAGKIREGKFR-RIPYR--YSDELNEIITRMLNLKDYHRP 260
Query: 311 GFTDFFNNEVVTEDLTRYEQSYEPDLESKSKDVAE------SNMFVSEYLVKPLKQQESA 364
+ N ++ DL EQ +LE + + + E S+ +SE +K ++ QE
Sbjct: 261 SVEEILENPLIA-DLVADEQ--RRNLERRGRQLGEPEKSQDSSPVLSELKLKEIQLQERE 317
Query: 365 HIPPTQTD--ENTSVQTGVRRTSGKERLA 391
+ + E + VR +++LA
Sbjct: 318 RALKAREERLEQKEQELCVRERLAEDKLA 346
>At1g49180_1 [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy
Length = 225
Score = 122 bits (307), Expect = 2e-27
Identities = 62/210 (29%), Positives = 110/210 (51%), Gaps = 42/210 (20%)
Query: 69 EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFE 128
E+ L + HP+I+ L+ + +++EYC G L+ +I++
Sbjct: 52 ELEFLSSVDHPNIIRLLHVSQDDDFLVMVLEYCDGGTLSSYIQR---------------- 95
Query: 129 HYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKT 188
+ + + +++Q+ + L+ + +++HRD+KP+N+L+
Sbjct: 96 --------YGRVEEDIAKRFMKQIGAGLEIIHDNHIIHRDLKPENILID----------- 136
Query: 189 FHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWS 248
G + +LKIADF AR L ET+CGSP YMAPE+L +Q+YN KAD+WS
Sbjct: 137 -------GSGDDLVLKIADFSLARKLHPGKYLETVCGSPFYMAPEVLQFQRYNEKADMWS 189
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKA 278
VG +L+E+ G PPF+ +N++++ + IK +
Sbjct: 190 VGAILFELLHGYPPFRGNNNVQVLRNIKSS 219
>Hs19424132 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 302
Score = 122 bits (305), Expect = 3e-27
Identities = 87/300 (29%), Positives = 142/300 (47%), Gaps = 52/300 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
N+ +EK+IG+G F+ VY+ L DG +A+K V EI +LK++ HP
Sbjct: 33 NFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHP 92
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIK---KRKNLVLKHPLIKTVFEHYPPPSTE 136
+++ ++ +++E GDL+ IK K+K L+ + + K
Sbjct: 93 NVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWK------------ 140
Query: 137 HNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVG 196
Y QL SAL+ + S+ ++HRDIKP N+ +
Sbjct: 141 -----------YFVQLCSALEHMHSRRVMHRDIKPANVFITAT----------------- 172
Query: 197 IYNLPILKIADFGFARFLPN-TSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYE 255
++K+ D G RF + T+ A +L G+P YM+PE ++ YN K+D+WS+G +LYE
Sbjct: 173 ----GVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYE 228
Query: 256 MCCGRPPFKAS--NHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFT 313
M + PF N L +KI++ D +PS+ Y E +L L+ + DP+ R T
Sbjct: 229 MAALQSPFYGDKMNLYSLCKKIEQC-DYPPLPSDHYSE-ELRQLVNMCINPDPEKRPDVT 286
>Hs14770402 [R] KOG0586 Serine/threonine protein kinase
Length = 926
Score = 122 bits (305), Expect = 3e-27
Identities = 86/291 (29%), Positives = 124/291 (42%), Gaps = 51/291 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +E +GKG+FAVV G +AIK + +S E+ I+K + HPH
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYR-EVQIMKMLDHPH 78
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ L T S YL+ EY G++ ++ H L
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYL------------------------ANHGRL 114
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
N Q+ SA+ + + +VHRD+K +NLLL N
Sbjct: 115 NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLD---------------------NN 153
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFGF F + L T CGSP Y APE+ Q+Y + D+WS+G VLY + CG
Sbjct: 154 MNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCG 213
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PF L Q++ + I ++ +LIR +L DP R+
Sbjct: 214 ALPFDGPTLPILRQRVLEGRFRIPY----FMSEDCEHLIRRMLVLDPSKRL 260
>SPCC1322.08 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 580
Score = 121 bits (304), Expect = 4e-27
Identities = 89/321 (27%), Positives = 155/321 (47%), Gaps = 51/321 (15%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX---------XXXXXXXVE 69
E Y++ +++G G+F+ VYK + R G +AIK V R+ E
Sbjct: 122 EQYTLLQKMGDGAFSNVYKAIHNRTGEKVAIKVVQRAQPNTDPRDPRKRQGVESHNILKE 181
Query: 70 IAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEH 129
+ I++++KHP+I+ L++ +T +YL++E G+L H +++ +
Sbjct: 182 VQIMRRVKHPNIIQLLEFIQTPEYYYLVLELADGGELF------------HQIVRLTY-- 227
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSK-NLVHRDIKPQNLLLCTPLLDY----- 183
+ L + + Q++ A+++L +VHRDIKP+NLL + +D+
Sbjct: 228 ----------FSEDLSRHVITQVAHAIRYLHEDCGVVHRDIKPENLLFDS--IDFVPSRV 275
Query: 184 ------NDPKTFHELGF---VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEI 234
+DP E F VG + +++ADFG ++ + + S +T CG+ Y APEI
Sbjct: 276 RKYRAGDDPDKVDEGEFIPGVGAGTIGRIRLADFGLSKVVWD-SHTQTPCGTMGYTAPEI 334
Query: 235 LNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKL 294
+ ++Y+ D+W++G VLY + CG PPF + L +K+ + P I
Sbjct: 335 VRDERYSKGVDMWALGCVLYTILCGFPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSA 394
Query: 295 FNLIRGLLTFDPDSRMGFTDF 315
+LI LLT DP+SR F
Sbjct: 395 KDLISHLLTVDPESRYDIHQF 415
>Hs13899225 [R] KOG0586 Serine/threonine protein kinase
Length = 688
Score = 121 bits (304), Expect = 4e-27
Identities = 100/413 (24%), Positives = 170/413 (40%), Gaps = 59/413 (14%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + + IGKG+ A V + GR +AIK + ++ E+ I+K + HP
Sbjct: 58 NYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFR-EVRIMKGLNHP 116
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YL+MEY + G++ ++ + K K
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAK--------------- 161
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+Q+ SA+ + KN+VHRD+K +NLLL
Sbjct: 162 ---------FRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN------------------ 194
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ S +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 195 ---IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVS 251
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N EL +++ + + Y+ +++R L +P R +
Sbjct: 252 GSLPFDGHNLKELRERVLRGKYRVPF----YMSTDCESILRRFLVLNPAKRCTLEQIMKD 307
Query: 319 EVVT-----EDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDE 373
+ + E+L Y + E ++K +V + E + + L Q+ + T
Sbjct: 308 KWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLL 367
Query: 374 NTSVQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSYQSASQKRLKSSYN 426
+ G R + LA P + +S+ + S Q+ S+Y+
Sbjct: 368 GRKTEEGGDRGAPGLALARVRAPSDTTNGTSSSKG---TSHSKGQRSSSSTYH 417
>CE27768 [R] KOG0586 Serine/threonine protein kinase
Length = 1096
Score = 121 bits (304), Expect = 4e-27
Identities = 102/421 (24%), Positives = 179/421 (42%), Gaps = 78/421 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K IGKG+FA V + G +AIK + ++ E+ I+K++ HP+
Sbjct: 122 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFR-EVKIMKQLDHPN 180
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L T YL++EY + G++ ++ + K K
Sbjct: 181 IVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAK---------------- 224
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+Q+ SA+++L SKN++HRD+K +NLLL D N
Sbjct: 225 --------FRQIVSAVQYLHSKNIIHRDLKAENLLLDQ---DMN---------------- 257
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFGF+ + +T CGSP Y APE+ + +KY+ + D+WS+G +LY + G
Sbjct: 258 --IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSG 315
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PF N EL +++ + I Y+ NL++ L +P R + +
Sbjct: 316 SLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKFLVINPQRRSSLDNIMKDR 371
Query: 320 VVTEDLTRYEQSYEPDLESKSKDVAESNM----------FVSEYLVKPLKQQESAHI--- 366
+ ++ + +P +E + E + F +++ +++++ I
Sbjct: 372 WM--NVGYEDDELKPFIEPPKDQIDEQRIEKLIQIFQLGFNKAAILESVEKEKFEDIHAT 429
Query: 367 ---------PPTQTDENTSVQTGVRRTSGKE-RLATNHPPHQQ--IHPEDNSQNPEQSYQ 414
P++ +++ TG T+G A N HQQ P S + +S Q
Sbjct: 430 YLLLGERKSDPSRYSRSSATATGASITAGSALASAANAQKHQQSSAAPSSGSSSSRRSSQ 489
Query: 415 S 415
+
Sbjct: 490 N 490
>CE05274 [T] KOG0690 Serine/threonine protein kinase
Length = 546
Score = 121 bits (304), Expect = 4e-27
Identities = 110/417 (26%), Positives = 177/417 (42%), Gaps = 61/417 (14%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX 60
M S + AK ++ E++ K +GKG+F V R + AIK + +
Sbjct: 173 MISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAR 232
Query: 61 XXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
E +L++ KHP + L +T+ +ME+ GDL + + +
Sbjct: 233 EEVAHTLTENRVLQRCKHPFLTELKYSFQTNDRLCFVMEFAIGGDLYYHLNRE------- 285
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
++ E + P G VL AL +L + ++V+RD+K +NLLL
Sbjct: 286 --VQMNKEGFSEPRARFYGSEIVL----------ALGYLHANSIVYRDLKLENLLL---- 329
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFAR----FLPNTSLAETLCGSPLYMAPEILN 236
K H +KIADFG + F TS T CG+P Y+APE+L+
Sbjct: 330 -----DKDGH------------IKIADFGLCKEEISFGDKTS---TFCGTPEYLAPEVLD 369
Query: 237 YQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFN 296
Y D W VG V+YEM CGR PF + +H +LF+ I ++ PS E +
Sbjct: 370 DHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAG--DLRFPSKLSQEAR--T 425
Query: 297 LIRGLLTFDPDSRMGFTDFFNNEVVTEDLTR-------YEQSYEPDLESKSKDVAESNMF 349
L+ GLL DP R+G E+ D R Y + EP + + +++ F
Sbjct: 426 LLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYF 485
Query: 350 VSEYLVKPLKQQESAHIPPTQT-DENTSVQTGVRRTSGKERLATNHPPHQQIHPEDN 405
+E+ +P++ + T DE +Q+ + S + + + H+ EDN
Sbjct: 486 DNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEA--SEDN 540
>HsM4505103 [R] KOG0586 Serine/threonine protein kinase
Length = 713
Score = 121 bits (303), Expect = 5e-27
Identities = 103/400 (25%), Positives = 167/400 (41%), Gaps = 58/400 (14%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K IGKG+FA V + GR +AIK + ++ E+ I+K + HP
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR-EVRIMKILNHP 113
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YLIMEY + G VF++ H
Sbjct: 114 NIVKLFEVIETQKTLYLIMEYASGGK--------------------VFDYL----VAHGR 149
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ + +Q+ SA+++ K +VHRD+K +NLLL D N
Sbjct: 150 MKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA---DMN--------------- 191
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 192 ---IKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N EL +++ + I Y+ NL++ L +P R +
Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
Query: 319 EVVT--EDLTRYEQSYEPDL---ESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDE 373
+ + + EP+L + K D+ + E + + L + + I T T
Sbjct: 305 RWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEI--TATYL 362
Query: 374 NTSVQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSY 413
++ R S +T PH ++ +S ++ Y
Sbjct: 363 LLGRKSSEVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRY 402
>Hs8923922 [R] KOG0586 Serine/threonine protein kinase
Length = 795
Score = 120 bits (302), Expect = 7e-27
Identities = 95/357 (26%), Positives = 157/357 (43%), Gaps = 58/357 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY ++K IGKG+FA V + GR +A+K + ++ E+ I+K + HP
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFR-EVRIMKILNHP 117
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YL+MEY + G++ ++ + K K
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK--------------- 162
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+Q+ SA+++ K +VHRD+K +NLLL D N
Sbjct: 163 ---------FRQIVSAVQYCHQKYIVHRDLKAENLLLDG---DMN--------------- 195
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ + +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 196 ---IKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 252
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N EL +++ + I Y+ NL++ LL +P R +
Sbjct: 253 GSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
Query: 319 EVVT-----EDLTRYEQSYEPDL-ESKSKDVAESNMFVSEYLVKPLKQQESAHIPPT 369
+ E+L Y + +PD ++K D+ + F + + L Q+ + T
Sbjct: 309 RWMNVGHEEEELKPYTEP-DPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMAT 364
>CE23838 [R] KOG0586 Serine/threonine protein kinase
Length = 1192
Score = 120 bits (302), Expect = 7e-27
Identities = 83/290 (28%), Positives = 133/290 (45%), Gaps = 51/290 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K IGKG+FA V + G +AIK + ++ E+ I+K++ HP+
Sbjct: 170 YKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFR-EVKIMKQLDHPN 228
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L T YL++EY + G++ ++ + K K
Sbjct: 229 IVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAK---------------- 272
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+Q+ SA+++L SKN++HRD+K +NLLL D N
Sbjct: 273 --------FRQIVSAVQYLHSKNIIHRDLKAENLLLDQ---DMN---------------- 305
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFGF+ + +T CGSP Y APE+ + +KY+ + D+WS+G +LY + G
Sbjct: 306 --IKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSG 363
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
PF N EL +++ + I Y+ NL++ L +P R
Sbjct: 364 SLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKFLVINPQRR 409
>7302464 [R] KOG0586 Serine/threonine protein kinase
Length = 739
Score = 120 bits (302), Expect = 7e-27
Identities = 90/326 (27%), Positives = 146/326 (44%), Gaps = 54/326 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K IGKG+FA V L G+ +AIK + ++ E+ I+K + HP+
Sbjct: 151 YKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFR-EVRIMKMLDHPN 209
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L T YLIMEY + G++ ++ + K +K
Sbjct: 210 IVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVK---------------- 253
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+Q+ SA+++ K ++HRD+K +NLLL + L
Sbjct: 254 --------FRQIVSAVQYCHQKRIIHRDLKAENLLLDSELN------------------- 286
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFGF+ S +T CGSP Y APE+ +KY+ + D+WS+G +LY + G
Sbjct: 287 --IKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG 344
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PF S EL +++ + I Y+ NL+R L +P R ++
Sbjct: 345 SLPFDGSTLRELRERVLRGKYRIPF----YMSTDCENLLRKFLVLNPAKRASLETIMGDK 400
Query: 320 VVTEDLTRYEQSYEPDLESKSKDVAE 345
+ ++ E +P +E K+ D+A+
Sbjct: 401 WM--NMGFEEDELKPYIEPKA-DLAD 423
>YPL203w [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 380
Score = 120 bits (301), Expect = 9e-27
Identities = 91/365 (24%), Positives = 167/365 (44%), Gaps = 62/365 (16%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX 60
++S+ K + + ++ + + +G GSF V+ S+ +GR AIK + +
Sbjct: 50 LTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKM 109
Query: 61 XXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
E +LK ++HP ++ + + + + +++M+Y G+L ++K
Sbjct: 110 KQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKS------- 162
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
+ +P P + Y ++ AL++L + N+++RD+KP+N+LL
Sbjct: 163 -------QRFPNPVAKF----------YAAEVILALEYLHAHNIIYRDLKPENILL---- 201
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY 240
D N +KI DFGFA+ + + TLCG+P Y+APE++ + Y
Sbjct: 202 -DRNGH----------------IKITDFGFAKEVQTVTW--TLCGTPDYIAPEVITTKPY 242
Query: 241 NAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRG 300
N D WS+G ++YEM G PF + ++ ++KI + ++ P Y P + +L+
Sbjct: 243 NKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQG--KVVYPP--YFHPDVVDLLSK 298
Query: 301 LLTFDPDSRMGFTDF---------FNNEVVTEDLTR--YEQSYEPDLESKSKDVAESNMF 349
L+T D R+G + +EVV E L E YEP + S D + + +
Sbjct: 299 LITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQY 358
Query: 350 VSEYL 354
E L
Sbjct: 359 PEEQL 363
>Hs7662170 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 661
Score = 120 bits (301), Expect = 9e-27
Identities = 83/300 (27%), Positives = 133/300 (43%), Gaps = 53/300 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +++ +GKG++ V + GR +AIK++ + EI I+ + HPH
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ + + +IMEY + G+L +I +R+ L + T H
Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSER--------------ETRH--- 157
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ +Q+ SA+ + +VHRD+K +N+ LLD N
Sbjct: 158 -------FFRQIVSAVHYCHKNGVVHRDLKLENI-----LLDDNCN-------------- 191
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFG + +T CGSPLY +PEI+N + Y + D W++G +LY + G
Sbjct: 192 --IKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYG 249
Query: 260 RPPFKASNHLELFQKIKKAN-DEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
PF +H L ++I E T PS+ LIR +L +PD R D N+
Sbjct: 250 TMPFDGFDHKNLIRQISSGEYREPTQPSDAR------GLIRWMLMVNPDRRATIEDIANH 303
>7290249 [R] KOG0586 Serine/threonine protein kinase
Length = 1398
Score = 120 bits (301), Expect = 9e-27
Identities = 105/419 (25%), Positives = 167/419 (39%), Gaps = 66/419 (15%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +E+ IGKG+FAVV +AIK + +S E+ I+K++KHPH
Sbjct: 141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYR-EVEIMKRLKHPH 199
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ L T + Y++ EY + G++ +I K + K
Sbjct: 200 IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFK---------------- 243
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
Q+ SA+++ K +VHRD+K +NLLL L+ N
Sbjct: 244 --------FWQIISAVEYCHKKGIVHRDLKAENLLLD---LNMN---------------- 276
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFGF+ L T CGSP Y APE+ ++Y + D+WS+G VLY + CG
Sbjct: 277 --IKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCG 334
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PF S L ++ I ++ + +LIR +L +P R +
Sbjct: 335 ALPFDGSTLQSLRDRVLSGRFRIPF----FMSSECEHLIRRMLVLEPTRRYTIDQIKRHR 390
Query: 320 VVTEDLTRY------------EQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIP 367
+ +L + + S EP E + +AE S+ LK+ H+
Sbjct: 391 WMCPELLEHVLIAKYNLGAERQTSVEPS-EDILRIMAEYVGIGSDKTRASLKKNTYDHVA 449
Query: 368 PTQ--TDENTSVQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSYQSASQKRLKSS 424
+ S + G LA++ + I+ N P Q K + +S
Sbjct: 450 AIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTS 508
>YAR018c [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 435
Score = 120 bits (300), Expect = 1e-26
Identities = 107/378 (28%), Positives = 173/378 (45%), Gaps = 41/378 (10%)
Query: 17 PTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKI 76
P Y V +EIG+GSF V K + + + + K + + E +IL ++
Sbjct: 21 PRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDI-KYGHMNSKERQQLIAECSILSQL 79
Query: 77 KHPHIVGLI--DCERTSSDFYLIMEYCALGDLTFFIK--KRKNLVLKHPLIKTVFEHYPP 132
KH +IV D + YL MEYC+ GDL+ IK K+++ + ++ +
Sbjct: 80 KHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLT 139
Query: 133 PSTE-HNGLNRVLVVNYLQQLSSALKFLRSKNLV-HRDIKPQNLLLCTPLLDYN--DPKT 188
+ H G+ + ++ +K KN+V HRD+KP N+ L DYN +
Sbjct: 140 ALYKCHYGVELPTLTTIYDRMKPPVK---GKNIVIHRDLKPGNIFLSYDDSDYNINEQVD 196
Query: 189 FHE----------------LGFVGIYNLPILKIADFGFARFLPNT-SLAETLCGSPLYMA 231
HE G Y+ ++K+ DFG A+ L + A T G+P YM+
Sbjct: 197 GHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMS 256
Query: 232 PEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIE 291
PE+L Q Y+ +D+WS+G V++EMC PPF+A N+LEL KIK + TVP Y
Sbjct: 257 PEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCD-TVPE--YYS 313
Query: 292 PKLFNLIRGLLTFDPDSRMGFTDFFNNEVV-----TEDLTRYEQ---SYEPDLESKSKDV 343
L +I ++ + +R + + + + L R+E+ YE +L + K +
Sbjct: 314 RGLNAIIHSMIDVNLRTRPSTFELLQDIQIRTARKSLQLERFERKLLDYENELTNIEK-I 372
Query: 344 AESNMFVSEYLVKPLKQQ 361
E E + LK+Q
Sbjct: 373 LEKQAIEYERELSQLKEQ 390
>7301734 [T] KOG0694 Serine/threonine protein kinase
Length = 739
Score = 120 bits (300), Expect = 1e-26
Identities = 92/344 (26%), Positives = 153/344 (43%), Gaps = 61/344 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK-KIKH 78
+++ K +GKGSF V AIK + + E IL H
Sbjct: 407 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANH 466
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P + L C +T + +MEY GDL F I+K +
Sbjct: 467 PFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAF--------------- 511
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
Y +++ AL+FL + +++RD+K N+LL + H
Sbjct: 512 ---------YAAEVTLALQFLHTHGVIYRDLKLDNILL---------DQEGH-------- 545
Query: 199 NLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
K+ADFG + + N L T CG+P Y+APEIL Q+Y A D W++G ++YEM
Sbjct: 546 ----CKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMM 601
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G+PPF+A N ELF I +D++ P ++ + ++++G LT +P+ R+G T N
Sbjct: 602 AGQPPFEADNEDELFDSI--MHDDVLYP--VWLSREAVSILKGFLTKNPEQRLGCTGDEN 657
Query: 318 N--------EVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEY 353
++ ++L + ++ +P K K+ ++N F +E+
Sbjct: 658 EIRKHPFFAKLDWKELEK--RNIKPPFRPKMKNPRDANNFDAEF 699
>Hs21361133 [R] KOG0586 Serine/threonine protein kinase
Length = 752
Score = 119 bits (299), Expect = 1e-26
Identities = 101/414 (24%), Positives = 176/414 (42%), Gaps = 47/414 (11%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K IGKG+FA V + GR +AIK + ++ E+ I+K + HP
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFR-EVRIMKILNHP 113
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YLIMEY + G++ ++ + K K + T
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSK-FRQGCQAGQTIKVQ 172
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
++ L+ + SA+++ K +VHRD+K +NLLL D N
Sbjct: 173 VSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDA---DMN--------------- 214
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 215 ---IKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 271
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF N EL +++ + I Y+ NL++ L +P R +
Sbjct: 272 GSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKRFLVLNPIKRGTLEQIMKD 327
Query: 319 EVVT--EDLTRYEQSYEPDL---ESKSKDVAESNMFVSEYLVKPLKQ------------- 360
+ + + EP+L + K D+ + E + + L +
Sbjct: 328 RWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLL 387
Query: 361 -QESAHIPPTQTDENTSVQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSY 413
++S+ + + + ++++ R S +T PH ++ +S ++ Y
Sbjct: 388 GRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHHKVQRSVSSSQKQRRY 441
>CE20167 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 722
Score = 119 bits (299), Expect = 1e-26
Identities = 83/288 (28%), Positives = 130/288 (44%), Gaps = 43/288 (14%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXX-VEIAILKKIKHPHIV 82
+K +G G F VY + G+ +A+K +S+ E+AIL++ HP IV
Sbjct: 429 DKTLGSGQFGTVYSAIQRHSGKEVAVKVISKERFSKKGSGAESMRAEVAILQQTCHPGIV 488
Query: 83 GLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNR 142
L T +++ME GD+ I S E LN
Sbjct: 489 CLEFMCETKDKIFVVMEKMN-GDMLEMIL----------------------SQELGRLNS 525
Query: 143 VLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPI 202
L Q+ ALK+L + + H D+KP+N+LL ++G N P
Sbjct: 526 RATKFLLVQILCALKYLHDQGIAHCDLKPENVLLS-------------DMGS----NFPQ 568
Query: 203 LKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPP 262
KI DFG+ARF+P + +T+ G+P Y+ PE+L + YN D+WSVG ++Y G P
Sbjct: 569 TKICDFGYARFIPESQFRKTVVGTPAYLPPEVLQRKGYNKSLDMWSVGVIIYVTLSGTFP 628
Query: 263 FKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
F E+ ++I+ A+ +EP +LI+ LL + ++RM
Sbjct: 629 FNEGE--EISEQIQNASFMFPTEPWSEVEPLAVDLIQKLLKVEIEARM 674
>7299438 [R] KOG0586 Serine/threonine protein kinase
Length = 705
Score = 119 bits (299), Expect = 1e-26
Identities = 90/291 (30%), Positives = 130/291 (43%), Gaps = 53/291 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + K +GKG+FA V + + GR +AIK + ++ E+ I+K + HP+
Sbjct: 98 YKIIKTLGKGNFAKVKLAIHVPTGREVAIKVIDKTQLNTSARQKLYR-EVKIMKLLNHPN 156
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + YL+MEY + G+L F+H
Sbjct: 157 IVRLFQVIESERTLYLVMEYASRGEL--------------------FDHLVKNGRMRERD 196
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
RV+ +QL SA+++ SK +VHRD+K +NLLL +
Sbjct: 197 ARVI----FRQLVSAIQYCHSKFVVHRDLKAENLLLDQHMN------------------- 233
Query: 201 PILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+KIADFGF F PN L ET CGSP Y APE+ +KY + D WS+G VLY +
Sbjct: 234 --IKIADFGFGNTFDPNAQL-ETFCGSPPYAAPELFMGRKYAGPEVDAWSLGVVLYTLVS 290
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G PF EL +++ + + YI NL+R L +P R
Sbjct: 291 GSLPFDGGTLKELRERVLRGKYRVPY----YISMDCENLMRKFLVLNPAKR 337
>YCL024w [T] KOG0583 Serine/threonine protein kinase
Length = 1037
Score = 119 bits (298), Expect = 2e-26
Identities = 97/342 (28%), Positives = 155/342 (44%), Gaps = 67/342 (19%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV--------EIAI 72
+ + + +G GS V R G A+K +S+S EI I
Sbjct: 21 WKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVI 80
Query: 73 LKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+K + HP+++ L D T+++ YLI+EY G+L NL++ +H P
Sbjct: 81 MKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELF-------NLLV---------DHGPL 124
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
P E +N +Q+ + + + +VHRD+KP+NLLL +
Sbjct: 125 PERE--------AINCFRQIIIGISYCHALGIVHRDLKPENLLLDS-------------- 162
Query: 193 GFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA-DLWSVGT 251
YN+ KIADFG A + L ET CGSP Y APEI++ Y A D+WS G
Sbjct: 163 ----FYNI---KIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGV 215
Query: 252 VLYEMCCGRPPF--KASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
+L+ + GR PF + N +L K++K E +P++ I +LI +L DP R
Sbjct: 216 ILFALLTGRLPFDEENGNVRDLLLKVQKGQFE--MPNDTEISRDAQDLIGKILVVDPRQR 273
Query: 310 MGFTDFFNNEVVTEDLTRYEQSYEPDLESKS-KDVAESNMFV 350
+ D ++ ++ + Y+ +SKS KD+ N ++
Sbjct: 274 IKIRDILSHPLL--------KKYQTIKDSKSIKDLPRENTYL 307
>Hs5453966 [T] KOG0583 Serine/threonine protein kinase
Length = 552
Score = 119 bits (297), Expect = 2e-26
Identities = 87/329 (26%), Positives = 139/329 (41%), Gaps = 50/329 (15%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R+ +Y + +G G+F V G G +A+K ++R EI LK
Sbjct: 10 RVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLK 69
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+HPHI+ L T +DF+++MEY + G+L +I K
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICK---------------------- 107
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
H + + QQ+ SA+ + +VHRD+KP+N+LL +
Sbjct: 108 --HGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHM-------------- 151
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVL 253
KIADFG + + + T CGSP Y APE+++ + Y + D+WS G +L
Sbjct: 152 -------NAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 254 YEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFT 313
Y + CG PF + LF+KI+ +P Y+ + L+ +L DP R
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIR--GGVFYIPE--YLNRSVATLLMHMLQVDPLKRATIK 260
Query: 314 DFFNNEVVTEDLTRYEQSYEPDLESKSKD 342
D +E + L Y +P ++ D
Sbjct: 261 DIREHEWFKQGLPSYLFPEDPSYDANVID 289
>At5g45810 [T] KOG0583 Serine/threonine protein kinase
Length = 483
Score = 119 bits (297), Expect = 2e-26
Identities = 77/263 (29%), Positives = 123/263 (46%), Gaps = 50/263 (19%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + +G G+FA VY + + G ++AIK + + EI+IL++++HP+
Sbjct: 28 YEMGRLLGHGTFAKVYLARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRHPN 87
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T S Y +MEY G+L + K + L
Sbjct: 88 IVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGR-------------------------L 122
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Y QQL SA+ F + + HRD+KP+NL LLD N
Sbjct: 123 KEEMARKYFQQLISAVSFCHFRGVYHRDLKPENL-----LLDENGN-------------- 163
Query: 201 PILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEM 256
LK++DFG + + L T CG+P Y+APE+L + Y+ AK D+WS G +L+ +
Sbjct: 164 --LKVSDFGLSAVSDQIRQDGLFHTFCGTPAYVAPEVLARKGYDGAKVDIWSCGVILFVL 221
Query: 257 CCGRPPFKASNHLELFQKIKKAN 279
G PF N + +++KI + +
Sbjct: 222 MAGFLPFHDRNVMAMYKKIYRGD 244
>Hs9966875 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 357
Score = 118 bits (296), Expect = 3e-26
Identities = 90/368 (24%), Positives = 155/368 (41%), Gaps = 44/368 (11%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
+ ++ +G G+F+ V G+ A+K + + EIA+L+KIKH +
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIEN--EIAVLRKIKHEN 80
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L D + + YL+M+ + G+L +++ F ST
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELF------------DRIVEKGFYTEKDAST----- 123
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
++Q+ A+ +L +VHRD+KP+NLL Y+ +
Sbjct: 124 -------LIRQVLDAVYYLHRMGIVHRDLKPENLLY------YSQDEESK---------- 160
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGR 260
+ I+DFG ++ + T CG+P Y+APE+L + Y+ D WS+G + Y + CG
Sbjct: 161 --IMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGY 218
Query: 261 PPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEV 320
PPF N +LF++I KA E P I + IR L+ DP+ R +
Sbjct: 219 PPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPW 278
Query: 321 VTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTSVQTG 380
+ D + +E K+ A+S + ++ H+ + N SV +
Sbjct: 279 IAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSS 338
Query: 381 VRRTSGKE 388
+ S K+
Sbjct: 339 LSLASQKD 346
>Hs9845489 [R] KOG0586 Serine/threonine protein kinase
Length = 691
Score = 118 bits (296), Expect = 3e-26
Identities = 82/291 (28%), Positives = 131/291 (44%), Gaps = 51/291 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K IGKG+FA V + G+ +A+K + ++ E+ I+K + HP
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR-EVRIMKVLNHP 77
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YL+MEY + G++ ++ + K K
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK--------------- 122
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+Q+ SA+++ K +VHRD+K +NLLL D N
Sbjct: 123 ---------FRQIVSAVQYCHQKFIVHRDLKAENLLLDA---DMN--------------- 155
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ + +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 156 ---IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 212
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G PF N EL +++ + I Y+ NL++ L +P R
Sbjct: 213 GSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKFLILNPSKR 259
>Hs9845487 [R] KOG0586 Serine/threonine protein kinase
Length = 745
Score = 118 bits (296), Expect = 3e-26
Identities = 82/291 (28%), Positives = 131/291 (44%), Gaps = 51/291 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K IGKG+FA V + G+ +A+K + ++ E+ I+K + HP
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR-EVRIMKVLNHP 77
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YL+MEY + G++ ++ + K K
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK--------------- 122
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+Q+ SA+++ K +VHRD+K +NLLL D N
Sbjct: 123 ---------FRQIVSAVQYCHQKFIVHRDLKAENLLLDA---DMN--------------- 155
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ + +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 156 ---IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 212
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G PF N EL +++ + I Y+ NL++ L +P R
Sbjct: 213 GSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKFLILNPSKR 259
>Hs22062450 [R] KOG0586 Serine/threonine protein kinase
Length = 787
Score = 118 bits (296), Expect = 3e-26
Identities = 82/291 (28%), Positives = 131/291 (44%), Gaps = 51/291 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + K IGKG+FA V + G+ +A+K + ++ E+ I+K + HP
Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFR-EVRIMKVLNHP 110
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T YL+MEY + G++ ++ + K K
Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAK--------------- 155
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+Q+ SA+++ K +VHRD+K +NLLL D N
Sbjct: 156 ---------FRQIVSAVQYCHQKFIVHRDLKAENLLLDA---DMN--------------- 188
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCC 258
+KIADFGF+ + +T CGSP Y APE+ +KY+ + D+WS+G +LY +
Sbjct: 189 ---IKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 245
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G PF N EL +++ + I Y+ NL++ L +P R
Sbjct: 246 GSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKFLILNPSKR 292
>At4g24400 [T] KOG0583 Serine/threonine protein kinase
Length = 445
Score = 118 bits (296), Expect = 3e-26
Identities = 92/309 (29%), Positives = 146/309 (46%), Gaps = 53/309 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + IG+G+FA V + G ++A+K V RS EI+I+K ++HP
Sbjct: 9 YELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPC 68
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V L + + + Y+I+EY G+L F K +N L
Sbjct: 69 VVRLYEVLASRTKIYIILEYITGGEL--FDKIVRN----------------------GRL 104
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Y QL + + SK + HRD+KP+NLLL +
Sbjct: 105 SESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDSQ--------------------- 143
Query: 201 PILKIADFGFARFLP--NTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEMC 257
LKI+DFG + LP ++ +T CG+P Y+APE+L+++ YN A AD+WS G +LY +
Sbjct: 144 GNLKISDFGLSA-LPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVADIWSCGVILYVLM 202
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G PF + L+ KI KA E + PS + K +LI +L +P++R+ +
Sbjct: 203 AGYLPFDEMDLPTLYSKIDKA--EFSCPSYFALGAK--SLINRILDPNPETRITIAEIRK 258
Query: 318 NEVVTEDLT 326
+E +D T
Sbjct: 259 DEWFLKDYT 267
>At2g25090 [T] KOG0583 Serine/threonine protein kinase
Length = 469
Score = 118 bits (296), Expect = 3e-26
Identities = 99/348 (28%), Positives = 147/348 (41%), Gaps = 70/348 (20%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV-EIAILKKIK 77
+ Y++ + +G G+FA VY G + G ++AIK + + EIA+++ ++
Sbjct: 13 DKYNIGRLLGTGNFAKVYHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLR 72
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP++V L + T + +MEY G+L I +
Sbjct: 73 HPNVVELREVMATKKKIFFVMEYVNGGELFEMIDR------------------------D 108
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
L L Y QQL SA+ F S+ + HRDIKP+NL LLD
Sbjct: 109 GKLPEDLARKYFQQLISAVDFCHSRGVFHRDIKPENL-----LLDGEGD----------- 152
Query: 198 YNLPILKIADFGFARFL----------PNTSLAETLCGSPLYMAPEILNYQKYN-AKADL 246
LK+ DFG + + + L T CG+P Y+APE+L + Y+ A AD+
Sbjct: 153 -----LKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLRNKGYDGAMADI 207
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
WS G VLY + G PF N + L+ KI KA E P +E K L+ LL DP
Sbjct: 208 WSCGIVLYALLAGFLPFIDENVMTLYTKIFKA--ECEFPPWFSLESK--ELLSRLLVPDP 263
Query: 307 DSRMGFTDF---------FNNEVVTEDLTRYEQSYEPDLESKSKDVAE 345
+ R+ ++ F V EP + K KD+ E
Sbjct: 264 EQRISMSEIKMIPWFRKNFTPSVAFSIDETIPSPPEPPTKKKKKDLNE 311
>Hs4507275 [D] KOG0580 Serine/threonine protein kinase
Length = 403
Score = 118 bits (295), Expect = 4e-26
Identities = 84/321 (26%), Positives = 146/321 (45%), Gaps = 50/321 (15%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E++ + + +GKG F VY + +A+K + ++ E+ I ++H
Sbjct: 131 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 190
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+I+ L ++ YLI+EY LG + ++K
Sbjct: 191 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---------------------- 228
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ Y+ +L++AL + SK ++HRDIKP+NLLL G G
Sbjct: 229 --DEQRTATYITELANALSYCHSKRVIHRDIKPENLLL----------------GSAGE- 269
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LKIADFG++ P+ S TLCG+ Y+ PE++ + ++ K DLWS+G + YE
Sbjct: 270 ----LKIADFGWSVHAPS-SRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV 324
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G+PPF+A+ + E +++I + E T P ++ +LI LL +P R + +
Sbjct: 325 GKPPFEANTYQETYKRISRV--EFTFPD--FVTEGARDLISRLLKHNPSQRPMLREVLEH 380
Query: 319 EVVTEDLTRYEQSYEPDLESK 339
+T + ++ + SK
Sbjct: 381 PWITANSSKPSNCQNKESASK 401
>At2g30360 [T] KOG0583 Serine/threonine protein kinase
Length = 435
Score = 118 bits (295), Expect = 4e-26
Identities = 87/295 (29%), Positives = 139/295 (46%), Gaps = 54/295 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV-EIAILKKIKHP 79
Y + K +G G+FA V+ R G+++A+K +++ EI+I++++ HP
Sbjct: 21 YELGKLLGCGAFAKVFHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHP 80
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L + T S + ME+ G+L I K H
Sbjct: 81 NIVKLHEVMATKSKIFFAMEFVKGGELFNKISK------------------------HGR 116
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L+ L Y QQL SA+ + ++ + HRD+KP+NL L+D N
Sbjct: 117 LSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENL-----LIDENGN------------- 158
Query: 200 LPILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYE 255
LK++DFG + + L TLCG+P Y+APEIL+ + Y AK D+WS G VL+
Sbjct: 159 ---LKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWSCGIVLFV 215
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ G PF N + +++KI K E P ++ P L + LL +P++R+
Sbjct: 216 LVAGYLPFNDPNVMNMYKKIYKG--EYRFPR--WMSPDLKRFVSRLLDINPETRI 266
>CE15235 [R] KOG0589 Serine/threonine protein kinase
Length = 357
Score = 117 bits (294), Expect = 6e-26
Identities = 83/305 (27%), Positives = 145/305 (47%), Gaps = 41/305 (13%)
Query: 19 ENYSVEKEIGKGSFAVVY--KGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKI 76
+NY + +G+G+F V + +G + + + IK ++ E+ +LKK+
Sbjct: 2 DNYEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQS-EVNLLKKV 60
Query: 77 KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTE 136
+HP I+G ID + ++M+Y G L I ++ +K ++ E++P +
Sbjct: 61 QHPLIIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQR--AIKDSNMR---EYFPEKT-- 113
Query: 137 HNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVG 196
V++Y Q+ AL + KN+VHRD+KPQN+L+ N KT
Sbjct: 114 --------VLDYFTQILIALNHMHQKNIVHRDLKPQNILM-------NRRKT-------- 150
Query: 197 IYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+LK++DFG ++ L S A T+ G+P Y++PEI + YN K+D+WS+G VLYE+
Sbjct: 151 -----VLKLSDFGISKELGTKSAASTVIGTPNYLSPEICESRPYNQKSDMWSLGCVLYEL 205
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
F N + KI ++ P ++ + L+ LL D R +
Sbjct: 206 LQLERAFDGENLPAIVMKITRSKQN---PLGDHVSNDVKMLVENLLKTHTDKRPDVSQLL 262
Query: 317 NNEVV 321
++ +V
Sbjct: 263 SDPLV 267
>At3g23000 [T] KOG0583 Serine/threonine protein kinase
Length = 429
Score = 117 bits (294), Expect = 6e-26
Identities = 95/330 (28%), Positives = 154/330 (45%), Gaps = 62/330 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH-P 79
Y + + +G GSFA V+ S+ +A+K + + EI +++++H P
Sbjct: 25 YELGRRLGSGSFAKVHLARSIESDELVAVKIIEKKKTIESGMEPRIIREIDAMRRLRHHP 84
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+I+ + + T S YL+ME + G+L + +R L P ST
Sbjct: 85 NILKIHEVMATKSKIYLVMELASGGELFSKVLRRGRL---------------PESTARR- 128
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
Y QQL+SAL+F + HRD+KPQNLLL E G
Sbjct: 129 --------YFQQLASALRFSHQDGVAHRDVKPQNLLL-------------DEQG------ 161
Query: 200 LPILKIADFGFARFLP---NTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYE 255
LK++DFG + LP L T CG+P Y APE+++ + Y+ AKAD WS G +L+
Sbjct: 162 --NLKVSDFGLSA-LPEHLQNGLLHTACGTPAYTAPEVISRRGYDGAKADAWSCGVILFV 218
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGF--- 312
+ G PF SN +++KI + + PS +I + ++I +L +P +RM
Sbjct: 219 LLVGDVPFDDSNIAAMYRKIHRR--DYRFPS--WISKQAKSIIYQMLDPNPVTRMSIETV 274
Query: 313 --TDFFNNEVVTEDLTRYEQSYEPDLESKS 340
T++F + T + R ++ ++E KS
Sbjct: 275 MKTNWFKKSLETSEFHR--NVFDSEVEMKS 302
>At2g38490 [T] KOG0583 Serine/threonine protein kinase
Length = 431
Score = 117 bits (294), Expect = 6e-26
Identities = 109/402 (27%), Positives = 179/402 (44%), Gaps = 78/402 (19%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDG-RNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
Y + K +G G+FA VY+ L++G ++AIK V + EI+++++++HP
Sbjct: 28 YDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKR-EISVMRRLRHP 86
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HIV L + T + Y +ME G+L + N
Sbjct: 87 HIVLLSEVLATKTKIYFVMELAKGGELFSRVTS-------------------------NR 121
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L Y +QL SA+++ ++ + HRD+KP+NLLL D N
Sbjct: 122 FTESLSRKYFRQLISAVRYCHARGVFHRDLKPENLLL-----DENRD------------- 163
Query: 200 LPILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYE 255
LK++DFG + + + TLCG+P Y+APE+L + Y+ +KAD+WS G VL+
Sbjct: 164 ---LKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFL 220
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD- 314
+ G PF+ N + L++KI KA + +P + L L+R LL +P+ R+ +
Sbjct: 221 LNAGYLPFRDPNIMGLYRKIHKA--QYKLPD--WTSSDLRKLLRRLLEPNPELRITVEEI 276
Query: 315 ----FFNNEVVTEDLTRYEQSYEPDLESKSK---------DVAESNM------FVSEYLV 355
+FN+ V ++ Q+ + DLE K + SN+ FV+
Sbjct: 277 LKDPWFNHGVDPSEIIGI-QADDYDLEENGKILNAFDLISSASSSNLSGLFGNFVTPDHC 335
Query: 356 KPLKQQESAHIPPTQTDENTSVQTGVRRTSGKERLATNHPPH 397
ES + + +E + Q +R KER PH
Sbjct: 336 DQFVSDESTAVIMRKVEE-VAKQLNLRIAKKKERAIKLEGPH 376
>7298652 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 459
Score = 117 bits (294), Expect = 6e-26
Identities = 87/315 (27%), Positives = 139/315 (43%), Gaps = 54/315 (17%)
Query: 12 KAIRLPTE---NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV 68
++I LP E Y V +++G G++ +V R + A+K V ++
Sbjct: 145 ESIGLPEEINKTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSD 204
Query: 69 ------EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPL 122
E I+K + HP +V + D Y+++E+ GDL N ++ + L
Sbjct: 205 PDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLL-------NRIISNKL 257
Query: 123 IKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLD 182
L+ + Y Q+ A+K+L + + HRD+KP N+LL T
Sbjct: 258 -----------------LSEDISKLYFYQMCHAVKYLHDRGITHRDLKPDNVLLET---- 296
Query: 183 YNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL---NYQK 239
ND +T +LK++DFG ++F+ S+ TLCG+PLY+APE+L +
Sbjct: 297 -NDEET-------------LLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREA 342
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
Y K D+WS+G VL+ G PF Q+IKK PS + + LI
Sbjct: 343 YTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLIN 402
Query: 300 GLLTFDPDSRMGFTD 314
+L DP+ R D
Sbjct: 403 QMLIVDPERRPSIDD 417
>YGL158w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 512
Score = 117 bits (293), Expect = 7e-26
Identities = 90/323 (27%), Positives = 149/323 (45%), Gaps = 45/323 (13%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYK--GLSLRDGRNIAIKAVSRSXXXXXX----------- 61
+L NY + +IG+G+F+ V+K G++ D +AIKA+ +
Sbjct: 115 QLELHNYKLLNKIGEGAFSRVFKAVGINTDDQAPVAIKAIIKKGISSDAILKGNDRIQGS 174
Query: 62 XXXXXXVEIAILKKIK--HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLK 119
E+AI K + +PH I + +++ +YL+ E G+
Sbjct: 175 SRKKVLNEVAIHKLVSKNNPHCTKFIAFQESANYYYLVTELVTGGE-------------- 220
Query: 120 HPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTP 179
+F+ + L R ++ Q++ A+K + +VHRD+KP+NLL P
Sbjct: 221 ------IFDRIVQLTCFSEDLARHVIT----QVAIAIKHMHYMGIVHRDVKPENLLF-EP 269
Query: 180 L----LDYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL 235
+ LD + K VG + ++K+ DFG A+ L N + A+T CG+ Y+A E+
Sbjct: 270 IPFYGLDGDMQKEDEFTLGVGGGGIGLVKLMDFGLAKKLRNNT-AKTPCGTIEYVASEVF 328
Query: 236 NYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLF 295
++Y+ K D+WS+G VL+ + CG PPF N L +KI + + E P I
Sbjct: 329 TSKRYSMKVDMWSIGCVLFTLLCGYPPFYEKNEKTLLKKISRGDYEFLAPWWDNISSGAK 388
Query: 296 NLIRGLLTFDPDSRMGFTDFFNN 318
N + LL DP+ R DF N+
Sbjct: 389 NAVTHLLEVDPNKRYDIDDFLND 411
>At4g30960 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 117 bits (293), Expect = 7e-26
Identities = 94/342 (27%), Positives = 154/342 (44%), Gaps = 67/342 (19%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + +G G+FA VY +++ G+++A+K V + EI++++ +KHP+
Sbjct: 24 YELGRLLGHGTFAKVYHARNIQTGKSVAMKVVGKEKVVKVGMVDQIKREISVMRMVKHPN 83
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + + S Y ME G+L + K + L
Sbjct: 84 IVELHEVMASKSKIYFAMELVRGGELFAKVAKGR-------------------------L 118
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Y QQL SA+ F S+ + HRD+KP+NLLL E G
Sbjct: 119 REDVARVYFQQLISAVDFCHSRGVYHRDLKPENLLL-------------DEEG------- 158
Query: 201 PILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEM 256
LK+ DFG + F L L T CG+P Y+APE++ + Y+ AKADLWS G +L+ +
Sbjct: 159 -NLKVTDFGLSAFTEHLKQDGLLHTTCGTPAYVAPEVILKKGYDGAKADLWSCGVILFVL 217
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PF+ N + +++KI + + P ++ L+ LL +P++R+
Sbjct: 218 LAGYLPFQDDNLVNMYRKIYRG--DFKCPG--WLSSDARRLVTKLLDPNPNTRITIEKVM 273
Query: 317 N------------NEVVTEDLTRYEQSYEPDLESKSKDVAES 346
+ NE V +T E+ + L KSK+ E+
Sbjct: 274 DSPWFKKQATRSRNEPVAATITTTEEDVD-FLVHKSKEETET 314
>At1g12580 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 522
Score = 117 bits (293), Expect = 7e-26
Identities = 86/319 (26%), Positives = 142/319 (43%), Gaps = 46/319 (14%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK- 77
+ Y + +++G G F V+ G +A K++S+ +EIAI+ K+
Sbjct: 42 DRYVLGEQLGWGQFGVIRVCSDKLTGERLACKSISKDRLVTQDDMKSIKLEIAIMAKLAG 101
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP++V L +L+ME CA G+L F K K + +F+H
Sbjct: 102 HPNVVNLKAVYEEKDSVHLVMELCAGGEL--FHKLEKYGRYSEVRARVLFKH-------- 151
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
L +KF +VHRD+KP+N+L+ T + + P
Sbjct: 152 --------------LMQVVKFCHDSGIVHRDLKPENILMAT--MSSSSP----------- 184
Query: 198 YNLPILKIADFGFARFL-PNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+K+ADFG A ++ P L+ T+ GSP Y+APE+L YN AD+WS G +LY +
Sbjct: 185 -----IKLADFGLATYIKPGEKLSGTV-GSPFYIAPEVLA-GGYNQAADVWSAGVILYIL 237
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PPF ++F ++ A+ + I +LIRG+L DP R+ +
Sbjct: 238 LSGAPPFWGKTKSKIFDAVRAADLRFSAEPWDNITSYAKDLIRGMLCVDPSQRLSADEVL 297
Query: 317 NNEVVTEDLTRYEQSYEPD 335
+ + + ++ Y+ D
Sbjct: 298 AHSWMEQLSESGQEQYDQD 316
>Hs14728804 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 576
Score = 117 bits (292), Expect = 9e-26
Identities = 88/293 (30%), Positives = 137/293 (46%), Gaps = 47/293 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
++Y + IG G+FAVV + + A+K + +S EI I++ + H
Sbjct: 282 KHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDS--EILIIQSLSH 339
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV L + T + YLI+EY GDL +I++V +P P
Sbjct: 340 PNIVKLHEVYETDMEIYLILEYVQGGDLF------------DAIIESV--KFPEPDA--- 382
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ L AL + K++VHRD+KP+NLL+ N+ K+
Sbjct: 383 -------ALMIMDLCKALVHMHDKSIVHRDLKPENLLV-----QRNEDKS---------- 420
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LK+ADFG A+ + T+CG+P Y+APEIL+ + Y + D+W+ G +LY + C
Sbjct: 421 --TTLKLADFGLAKHVVRPIF--TVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLC 476
Query: 259 GRPPFKA--SNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G PPF++ + ELF I+ + E P I +L+ LL DP R
Sbjct: 477 GFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKR 529
>YDR507c [D] KOG0588 Serine/threonine protein kinase
Length = 1142
Score = 116 bits (291), Expect = 1e-25
Identities = 96/337 (28%), Positives = 149/337 (43%), Gaps = 72/337 (21%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV------------ 68
+ + + +G GS V + G+ A+K +S++ V
Sbjct: 19 WKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGI 78
Query: 69 --EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTV 126
EI I+K + HP+++ L D T++D YL++EY G+L + +R
Sbjct: 79 EREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERG------------ 126
Query: 127 FEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDP 186
P EH + + +Q+ + + + +VHRD+KP+NLLL D
Sbjct: 127 ------PLPEHEA------IRFFRQIIIGVSYCHALGIVHRDLKPENLLL--------DH 166
Query: 187 KTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA-D 245
K YN+ KIADFG A L ET CGSP Y APEI++ Y A D
Sbjct: 167 K----------YNI---KIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASD 213
Query: 246 LWSVGTVLYEMCCGRPPF--KASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLT 303
+WS G +L+ + GR PF + N L K++K E +PS+ I + +LIR +LT
Sbjct: 214 VWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKG--EFEMPSDDEISREAQDLIRKILT 271
Query: 304 FDPDSRMGFTDFFNNEVVTEDLTRYEQSYEPDLESKS 340
DP+ R+ D + ++ Q Y +SKS
Sbjct: 272 VDPERRIKTRDILKHPLL--------QKYPSIRDSKS 300
>HsM8923212 [T] KOG4717 Serine/threonine protein kinase
Length = 244
Score = 116 bits (290), Expect = 2e-25
Identities = 83/275 (30%), Positives = 129/275 (46%), Gaps = 49/275 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y ++K +G+G FAVV + G +A+K + ++ E+ +K ++HP+
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQ-EVRCMKLVQHPN 74
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T + YLI+E GD+ +I K + GL
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEE-----------------------GL 111
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
N L Y Q+ A+ + ++VHRD+KP+N++ F + G V
Sbjct: 112 NEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVF------------FEKQGLV----- 154
Query: 201 PILKIADFGFA-RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA-DLWSVGTVLYEMCC 258
K+ DFGF+ +F P L T CGS Y APEIL +Y+A A D+WS+G +L+ + C
Sbjct: 155 ---KLTDFGFSNKFQPGKKLT-TSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVC 210
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPK 293
+PPF+ +N E I + TVPS+ E K
Sbjct: 211 EQPPFQEANDSETLTMIMDC--KYTVPSHVSKECK 243
>Hs5453976 [T] KOG0694 Serine/threonine protein kinase
Length = 706
Score = 116 bits (290), Expect = 2e-25
Identities = 98/348 (28%), Positives = 150/348 (42%), Gaps = 58/348 (16%)
Query: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAIL 73
I+L E++ + K +GKGSF V+ + + AIKA+ + VE +L
Sbjct: 373 IKLKIEDFILHKMLGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVL 432
Query: 74 KKI-KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+HP + + +T + + +MEY GDL + I+ K L + F
Sbjct: 433 SLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCH----KFDLSRATF----- 483
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
Y ++ L+FL SK +V+RD+K N+LL K H
Sbjct: 484 ---------------YAAEIILGLQFLHSKGIVYRDLKLDNILL---------DKDGH-- 517
Query: 193 GFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGT 251
+KIADFG + + + T CG+P Y+APEIL QKYN D WS G
Sbjct: 518 ----------IKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGV 567
Query: 252 VLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
+LYEM G+ PF + ELF I+ N ++E + +L+ L +P+ R+G
Sbjct: 568 LLYEMLIGQSPFHGQDEEELFHSIRMDNPFYP----RWLEKEAKDLLVKLFVREPEKRLG 623
Query: 312 FTDFFN-----NEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYL 354
E+ E+L R E +P K K + + F E+L
Sbjct: 624 VRGDIRQHPLFREINWEELERKE--IDPPFRPKVKSPFDCSNFDKEFL 669
>YPL209c [D] KOG0580 Serine/threonine protein kinase
Length = 367
Score = 115 bits (289), Expect = 2e-25
Identities = 78/308 (25%), Positives = 140/308 (45%), Gaps = 49/308 (15%)
Query: 7 DKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXX 66
+K + K L +++ + K++GKG F VY G A+K + +
Sbjct: 90 NKKLPKFKSLSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQF 149
Query: 67 XVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTV 126
E+ I + HP++ YL+MEY G++ ++
Sbjct: 150 RREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRL-------------- 195
Query: 127 FEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDP 186
H N +L +Y+ Q+++AL ++ KN++HRDIKP+N+L
Sbjct: 196 ----------HGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENIL----------- 234
Query: 187 KTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADL 246
+G N ++K+ DFG++ P + +T+CG+ Y++PE++ ++Y+ D
Sbjct: 235 --------IGFNN--VIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDA 284
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
W++G + +E+ G PPF+ +++I A +I +PSN I +LI LL +DP
Sbjct: 285 WALGVLAFELLTGAPPFEEEMKDTTYKRI--AALDIKMPSN--ISQDAQDLILKLLKYDP 340
Query: 307 DSRMGFTD 314
RM D
Sbjct: 341 KDRMRLGD 348
>At4g14580 [T] KOG0583 Serine/threonine protein kinase
Length = 426
Score = 115 bits (289), Expect = 2e-25
Identities = 91/296 (30%), Positives = 137/296 (45%), Gaps = 56/296 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKI-KHP 79
Y + + +G GSFA V+ S+ G +AIK + + EI ++++ HP
Sbjct: 21 YELGRRLGSGSFAKVHVARSISTGELVAIKIIDKQKTIDSGMEPRIIREIEAMRRLHNHP 80
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+++ + + T S YL++EY A G+L F K LI+
Sbjct: 81 NVLKIHEVMATKSKIYLVVEYAAGGEL--FTK----------LIR------------FGR 116
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
LN Y QQL+SAL F + HRD+KPQNLLL
Sbjct: 117 LNESAARRYFQQLASALSFCHRDGIAHRDVKPQNLLL---------------------DK 155
Query: 200 LPILKIADFGFARFLP----NTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLY 254
LK++DFG + LP N L T CG+P Y APE++ + Y+ AKAD WS G L+
Sbjct: 156 QGNLKVSDFGLSA-LPEHRSNNGLLHTACGTPAYTAPEVIAQRGYDGAKADAWSCGVFLF 214
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ G PF +N + +++KI K + PS +I ++I LL +P++RM
Sbjct: 215 VLLAGYVPFDDANIVAMYRKIHKR--DYRFPS--WISKPARSIIYKLLDPNPETRM 266
>At2g26980 [T] KOG0583 Serine/threonine protein kinase
Length = 441
Score = 115 bits (289), Expect = 2e-25
Identities = 108/413 (26%), Positives = 181/413 (43%), Gaps = 78/413 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y V + IG+G+FA V + G +A+K + + EIA +K IKHP+
Sbjct: 14 YEVGRTIGEGTFAKVKFARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPN 73
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V L + + + ++I+EY G+L F K + +K +
Sbjct: 74 VVQLYEVMASKTKIFIILEYVTGGEL--FDKIVNDGRMKEDEAR---------------- 115
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
Y QQL A+ + S+ + HRD+KP+NLLL + Y +
Sbjct: 116 ------RYFQQLIHAVDYCHSRGVYHRDLKPENLLLDS----YGN--------------- 150
Query: 201 PILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEM 256
LKI+DFG + + + L T CG+P Y+APE+LN + Y+ A AD+WS G VLY +
Sbjct: 151 --LKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYDGATADMWSCGVVLYVL 208
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
G PF SN + L++KI ++ E P ++ LI +L +P +R+ + F
Sbjct: 209 LAGYLPFDDSNLMNLYKKI--SSGEFNCPP--WLSLGAMKLITRILDPNPMTRVTPQEVF 264
Query: 317 NNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTS 376
+E +D +E +S D+ E+LV ++++ A I E S
Sbjct: 265 EDEWFKKDYK--PPVFEERDDSNMDDIDAVFKDSEEHLVTEKREEQPAAI---NAFEIIS 319
Query: 377 VQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSYQSASQKRLKSSYNDLI 429
+ G+ +N +PEQ ++ ++ L+ N++I
Sbjct: 320 MSRGLNL--------------------ENLFDPEQEFKRETRITLRGGANEII 352
>SPCC320.12c [D] KOG0580 Serine/threonine protein kinase
Length = 384
Score = 115 bits (288), Expect = 3e-25
Identities = 79/291 (27%), Positives = 136/291 (46%), Gaps = 51/291 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
+ + K +GKG F VY + G +A+K + +S EI I ++H +
Sbjct: 118 FEIGKPLGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKN 177
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ L YLI+E+ G+L +++ K
Sbjct: 178 ILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRF------------------------ 213
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ + Y+ Q+++AL +L K+++HRDIKP+N+LL G G
Sbjct: 214 SEEVASKYIFQMANALSYLHKKHVIHRDIKPENILL----------------GIDGE--- 254
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGR 260
+K++DFG++ P+ TLCG+ Y+ PE++ +++ K DLWS+G + YE G
Sbjct: 255 --IKLSDFGWSVHAPSNRRT-TLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGA 311
Query: 261 PPFK-ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PPF+ S H +++I K ++ +PS ++ P +LI LL +P+ RM
Sbjct: 312 PPFEDMSGHSATYKRIAKV--DLKIPS--FVPPDARDLISRLLQHNPEKRM 358
>HsM4507279 [D] KOG0580 Serine/threonine protein kinase
Length = 402
Score = 115 bits (288), Expect = 3e-25
Identities = 83/321 (25%), Positives = 145/321 (44%), Gaps = 50/321 (15%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E++ + + +GKG F VY + +A+K + ++ E+ I ++H
Sbjct: 130 EDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRH 189
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+I+ L ++ YLI+EY LG + ++K
Sbjct: 190 PNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKF---------------------- 227
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ N ++++AL + SK ++HRDIKP+NLLL G G
Sbjct: 228 --DEQRTANLYNRIANALSYCHSKRVIHRDIKPENLLL----------------GSAGE- 268
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LKIADFG++ P+ S TLCG+ Y+ PE++ + ++ K DLWS+G + YE
Sbjct: 269 ----LKIADFGWSVHAPS-SRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLV 323
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G+PPF+A+ + E +++I + E T P ++ +LI LL +P R + +
Sbjct: 324 GKPPFEANTYQETYKRISRV--EFTFPD--FVTEGARDLISRLLKHNPSQRPMLREVLEH 379
Query: 319 EVVTEDLTRYEQSYEPDLESK 339
+T + ++ + SK
Sbjct: 380 PWITANSSKPSNCQNKESASK 400
>SPAC17G8.14c [T] KOG0694 Serine/threonine protein kinase
Length = 896
Score = 115 bits (287), Expect = 4e-25
Identities = 97/357 (27%), Positives = 153/357 (42%), Gaps = 69/357 (19%)
Query: 12 KAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVE-- 69
K R+ ++++ +GKG+F V + + AIK + + E
Sbjct: 563 KKNRVTLDDFTFLAVLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKH 622
Query: 70 -IAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFE 128
+ K KHP ++ L +TS+ Y +MEY GDL I++++ V +
Sbjct: 623 VFEVANKEKHPFLLNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQFSVKRARF------ 676
Query: 129 HYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKT 188
Y ++ ALK+ + +RD+K N+LLC
Sbjct: 677 -------------------YGAEVCLALKYFHENGIAYRDLKLDNILLCPD--------- 708
Query: 189 FHELGFVGIYNLPILKIADFGFAR---FLPNTSLAETLCGSPLYMAPEILNYQKYNAKAD 245
++IAD+G + L NT+ T CG+P +MAPEIL Q+Y+ D
Sbjct: 709 ------------GHIRIADYGLCKENMLLGNTT--STFCGTPEFMAPEILLEQQYSKDVD 754
Query: 246 LWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFD 305
W+ G ++Y+M G+ PFK + E+F I +DE P N + +L+RGLLT D
Sbjct: 755 WWAFGVLMYQMLLGQSPFKGEDEEEIFDAI--LSDEPLFPIN--MPADAVSLLRGLLTRD 810
Query: 306 PDSRMGFTDFFNNEV---------VTEDLTRYEQSYEPDLESKSKDVAESNMFVSEY 353
P+ R+G NEV V +DL Y + YEP + D + N F E+
Sbjct: 811 PNQRLGSGPKDANEVMAHPFFASIVWDDL--YNKLYEPSYKPLINDPRDLNNFDEEF 865
>Hs5453972 [T] KOG0694 Serine/threonine protein kinase
Length = 682
Score = 115 bits (287), Expect = 4e-25
Identities = 87/312 (27%), Positives = 133/312 (41%), Gaps = 51/312 (16%)
Query: 2 SSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXX 61
S E + V + RL +N+ + +GKGSF V G A+K + +
Sbjct: 335 SKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDD 394
Query: 62 XXXXXXVEIAILKKIK-HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
E IL + HP + L C +T + +ME+ GDL F I+K +
Sbjct: 395 DVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRF---- 450
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
+ Y ++ SAL FL K +++RD+K N+LL
Sbjct: 451 --------------------DEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLD--- 487
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQK 239
HE K+ADFG + + N T CG+P Y+APEIL
Sbjct: 488 ---------HE---------GHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEML 529
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
Y D W++G +LYEM CG PF+A N +LF+ I NDE+ P+ ++ +++
Sbjct: 530 YGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAI--LNDEVVYPT--WLHEDATGILK 585
Query: 300 GLLTFDPDSRMG 311
+T +P R+G
Sbjct: 586 SFMTKNPTMRLG 597
>Hs4557511 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 454
Score = 115 bits (287), Expect = 4e-25
Identities = 80/295 (27%), Positives = 132/295 (44%), Gaps = 44/295 (14%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSR---SXXXXXXXXXXXXVEIAILKK 75
++Y + +E+G G FA+V K G+ A K + + S E+ IL++
Sbjct: 11 DHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILRE 70
Query: 76 IKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPST 135
I+HP+I+ L D +D LI+E + G+L F+ ++++L T
Sbjct: 71 IRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESL------------------T 112
Query: 136 EHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFV 195
E +L+Q+ + +L SK + H D+KP+N++L LD N P
Sbjct: 113 EDEA------TQFLKQILDGVHYLHSKRIAHFDLKPENIML----LDKNVPN-------- 154
Query: 196 GIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYE 255
P +K+ DFG A + + + + G+P ++APEI+NY+ +AD+WS+G + Y
Sbjct: 155 -----PRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYI 209
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ G PF E I N + + IR LL DP RM
Sbjct: 210 LLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRM 264
>CE21239 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 115 bits (287), Expect = 4e-25
Identities = 78/304 (25%), Positives = 135/304 (43%), Gaps = 53/304 (17%)
Query: 12 KAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIA 71
K + L T N ++G+G ++ VYK + R +A+KA+ E++
Sbjct: 90 KGMDLDTSN-----KLGRGKYSKVYKAFDRNNNRVVAVKAIDTQELTTDVKMKFLPRELS 144
Query: 72 ILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYP 131
+K+K+P +VGL S +L MEY + GDL +++
Sbjct: 145 CWRKLKNPFVVGLHAQYEAQSMIFLTMEYGSQGDLLRYVQ-------------------- 184
Query: 132 PPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
EH G++ ++ QL L+F+ S N+ HRDIK +N++L
Sbjct: 185 ----EHGGIHEQKAGLFMSQLIRGLQFMHSINIAHRDIKLENIILFD------------- 227
Query: 192 LGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVG 250
+K++DFGF R + ++L+ T CGS Y APE+L YN +D+WS+G
Sbjct: 228 ---------NCVKLSDFGFVRKMDESALSSTFCGSKSYSAPELLRGIVYNPFLSDVWSLG 278
Query: 251 TVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
V + M R PF + ++++ N + +P + ++ + ++ FD +R
Sbjct: 279 VVGFVMVTNRMPFDEKKPNNVIVELQR-NRQYVIPHSVFLSTSCISSFESMMAFDTRNRP 337
Query: 311 GFTD 314
TD
Sbjct: 338 TSTD 341
>CE05507 [T] KOG0603 Ribosomal protein S6 kinase
Length = 785
Score = 115 bits (287), Expect = 4e-25
Identities = 97/320 (30%), Positives = 142/320 (44%), Gaps = 80/320 (25%)
Query: 27 IGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-HPHIVGLI 85
+GKG+F+VV + + DG A+K VS+ E IL+ ++ HP+IV L
Sbjct: 388 LGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQAQR------EARILEMVQGHPNIVQLH 441
Query: 86 DCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLV 145
D FYL+ME +L I+K + TE
Sbjct: 442 DVHSDPLHFYLVMEILTGNELLERIRKLERF------------------TESEA------ 477
Query: 146 VNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKI 205
+ ++QL SA+K+L K +VHRD+KP+N+L F I + L++
Sbjct: 478 ADIMRQLVSAVKYLHDKRIVHRDLKPENIL------------------FESIDSSARLRL 519
Query: 206 ADFGFARFLPNT----------------------SL-AETLCGSPLYMAPEIL----NYQ 238
DFGFAR LPN+ SL +ET C + Y APE+L +
Sbjct: 520 VDFGFARLLPNSMEQQLKSVQVLRKMYGLIAHNHSLHSETPCFTLQYAAPEVLDVGDSQP 579
Query: 239 KYNAKADLWSVGTVLYEMCCGRPPFKASNH----LELFQKIKKANDEITVPSNCYIEPKL 294
+YN + DLWS+G VL+ M G+ PF A + E+ Q+I +A T + +
Sbjct: 580 EYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADA 639
Query: 295 FNLIRGLLTFDPDSRMGFTD 314
NLI GLLT DP R+ +
Sbjct: 640 KNLITGLLTVDPKKRLSMQE 659
Score = 64.7 bits (156), Expect = 6e-10
Identities = 73/315 (23%), Positives = 132/315 (41%), Gaps = 54/315 (17%)
Query: 7 DKVVAKAIRLPTENYSVEKEIGKGSFAVVY--KGLSLRDGRNIAIKAVSRSXXXXXXXXX 64
D ++ + ++ EN+++ + +GKG++ V+ + + +D I V R
Sbjct: 3 DILMPEGEKVSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKT 62
Query: 65 X--XXVEIAILKKIKH-PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHP 121
E +L++++ P +V L +T + +++MEY G+L
Sbjct: 63 LEHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGEL--------------- 107
Query: 122 LIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLL 181
F H S H L V + +L A+ L + +++RD+K +N+LL
Sbjct: 108 -----FTHLC--SRGHFDLEAARFV--IAELVVAIDSLHQRKVIYRDLKLENILL----- 153
Query: 182 DYNDPKTFHELGFVGIYNLPILKIADFGFAR-FLPNT-SLAETLCGSPLYMAPEILNYQK 239
E G V K+ DFG ++ FLP A + CG+ YM+PE++N +
Sbjct: 154 --------DEEGHV--------KLTDFGLSKLFLPGELDRANSYCGTIEYMSPEVINRPE 197
Query: 240 --YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNL 297
Y+ D WS+G + +E+ G PF + I K VP ++ +
Sbjct: 198 GGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMDVDARDF 257
Query: 298 IRGLLTFDPDSRMGF 312
I LL + R+G+
Sbjct: 258 IGQLLEKKLEKRLGY 272
>Hs4502023 [T] KOG0690 Serine/threonine protein kinase
Length = 481
Score = 114 bits (286), Expect = 5e-25
Identities = 91/312 (29%), Positives = 140/312 (44%), Gaps = 51/312 (16%)
Query: 2 SSESHDKVVAKAIRLPTEN-YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX 60
++E + V+KA T N + K +GKG+F V GR A+K + +
Sbjct: 132 TTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAK 191
Query: 61 XXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
E +L+ +HP + L +T +MEY G+L F + + +
Sbjct: 192 DEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRER------ 245
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
VF TE Y ++ SAL++L S+++V+RDIK +NL+L
Sbjct: 246 -----VF-------TEERAR------FYGAEIVSALEYLHSRDVVYRDIKLENLML---- 283
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQK 239
K H +KI DFG + + + + +T CG+P Y+APE+L
Sbjct: 284 -----DKDGH------------IKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDND 326
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
Y D W +G V+YEM CGR PF +H LF+ I +EI P + P+ +L+
Sbjct: 327 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELI--LMEEIRFPRT--LSPEAKSLLA 382
Query: 300 GLLTFDPDSRMG 311
GLL DP R+G
Sbjct: 383 GLLKKDPKQRLG 394
>Hs4826684_1 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 114 bits (286), Expect = 5e-25
Identities = 82/297 (27%), Positives = 130/297 (43%), Gaps = 44/297 (14%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV---EIAILKKIK 77
Y +E+G G FAVV K G A K + + E++ILK+I+
Sbjct: 13 YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ 72
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+++ L + +D LI+E A G+L F+ ++++L TE
Sbjct: 73 HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESL------------------TEE 114
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+L+Q+ + + +L S + H D+KP+N++L LD N PK
Sbjct: 115 EA------TEFLKQILNGVYYLHSLQIAHFDLKPENIML----LDRNVPK---------- 154
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
P +KI DFG A + + + + G+P ++APEI+NY+ +AD+WS+G + Y +
Sbjct: 155 ---PRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILL 211
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
G PF E + N E + IR LL DP RM D
Sbjct: 212 SGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQD 268
>Hs21361433 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 114 bits (285), Expect = 6e-25
Identities = 89/332 (26%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 10 VAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVE 69
+A I E++ V +GKGSFA VY+ S+ G +AIK + + E
Sbjct: 1 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNE 60
Query: 70 IAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEH 129
+ I ++KHP I+ L + S+ YL++E C G++ ++K R
Sbjct: 61 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-------------- 106
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTF 189
P +E+ +++ Q+ + + +L S ++HRD+ NLLL +
Sbjct: 107 ---PFSENEAR------HFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM--------- 148
Query: 190 HELGFVGIYNLPILKIADFGFARFLPNTSLAE-TLCGSPLYMAPEILNYQKYNAKADLWS 248
+KIADFG A L TLCG+P Y++PEI + ++D+WS
Sbjct: 149 ------------NIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWS 196
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G + Y + GRPPF K+ A+ E +P+ IE K +LI LL +P
Sbjct: 197 LGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYE--MPTFLSIEAK--DLIHQLLRRNPAD 252
Query: 309 RMGFTDFF-------NNEVVTEDLTRYEQSYE 333
R+ + N+ ++DL E S +
Sbjct: 253 RLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID 284
>At3g08730 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 465
Score = 114 bits (285), Expect = 6e-25
Identities = 86/294 (29%), Positives = 136/294 (46%), Gaps = 52/294 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+++ V K +GKG+F VY+ A+K + + E IL KI H
Sbjct: 132 DDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDH 191
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P IV L +T YL++++ G L F + H
Sbjct: 192 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLY-------------------------HQ 226
Query: 139 GLNRV-LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
GL R L Y ++ SA+ L K ++HRD+KP+N+L+ T G V
Sbjct: 227 GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTD-------------GHV-- 271
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+ DFG A+ + + ++CG+ YMAPEI+ + ++ AD WSVG +LYEM
Sbjct: 272 ------MLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEML 325
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
G+PPF S ++ QKI K D+I +P ++ + +++GLL +P+ R+G
Sbjct: 326 TGKPPFLGSKG-KIQQKIVK--DKIKLPQ--FLSNEAHAILKGLLQKEPERRLG 374
>HsM7657627 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 970
Score = 114 bits (284), Expect = 8e-25
Identities = 89/332 (26%), Positives = 146/332 (43%), Gaps = 56/332 (16%)
Query: 10 VAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVE 69
+A I E++ V +GKGSFA VY+ S+ G +AIK + + E
Sbjct: 1 MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNE 60
Query: 70 IAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEH 129
+ I ++KHP I+ L + S+ YL++E C G++ ++K R
Sbjct: 61 VKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-------------- 106
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTF 189
P +E+ +++ Q+ + + +L S ++HRD+ NLLL +
Sbjct: 107 ---PFSENEAR------HFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNM--------- 148
Query: 190 HELGFVGIYNLPILKIADFGFARFLPNTSLAE-TLCGSPLYMAPEILNYQKYNAKADLWS 248
+KIADFG A L TLCG+P Y++PEI + ++D+WS
Sbjct: 149 ------------NIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWS 196
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G + Y + GRPPF K+ A+ E +P+ IE K +LI LL +P
Sbjct: 197 LGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYE--MPTFLSIEAK--DLIHQLLRRNPAD 252
Query: 309 RMGFTDFF-------NNEVVTEDLTRYEQSYE 333
R+ + N+ ++DL E S +
Sbjct: 253 RLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID 284
>Hs7657214 [T] KOG0583 Serine/threonine protein kinase
Length = 714
Score = 114 bits (284), Expect = 8e-25
Identities = 93/312 (29%), Positives = 136/312 (42%), Gaps = 51/312 (16%)
Query: 20 NYSV-EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV-EIAILKKIK 77
NY + +++G+GSFA V +GL + G +AIK + + E I + I+
Sbjct: 60 NYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIR 119
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+I L+D T + +YL+ME C G+L I ++K L E
Sbjct: 120 HPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRL-------------------EE 160
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+ R Y++QL SA++ L +VHRD+K +NLLL D N
Sbjct: 161 SEARR-----YIRQLISAVEHLHRAGVVHRDLKIENLLLDE---DNN------------- 199
Query: 198 YNLPILKIADFGF---ARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
+K+ DFG A L + T CGSP Y APE+L +KY K D+WS+G +Y
Sbjct: 200 -----IKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMY 254
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
M G PF L +K D+ P + + +R LL DP R
Sbjct: 255 AMLTGTLPFTV-EPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQ 313
Query: 315 FFNNEVVTEDLT 326
N + E+ T
Sbjct: 314 ALANRWLNENYT 325
>CE18454 [T] KOG4717 Serine/threonine protein kinase
Length = 1016
Score = 114 bits (284), Expect = 8e-25
Identities = 84/290 (28%), Positives = 134/290 (45%), Gaps = 50/290 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y +EK IG+G FAVV + G +A+K + ++ E+ +K ++H +
Sbjct: 27 YDLEKTIGQGHFAVVKLAKHVFTGEMVAVKIIDKTKMDEASTSQIMK-EVRCMKLVQHAN 85
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + T + +LI+E LGD + ++KH G+
Sbjct: 86 IVRLYEVLDTQTKIFLILE---LGDYDLH-----DFIIKH----------------EKGV 121
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
L Y Q+ +A+ + ++VHRD+KP+N++ F +LG V
Sbjct: 122 CESLAQQYFCQIMTAIDYCHQLHVVHRDLKPENVVF------------FEKLGMV----- 164
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKA-DLWSVGTVLYEMCCG 259
K+ DFGF+ T CGS Y APEIL Y+A A D+WS+G +LY + CG
Sbjct: 165 ---KLTDFGFSNSYEPGEQLNTSCGSLAYSAPEILLGDSYDAPAVDVWSLGVILYMLVCG 221
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
R PF+ +N E KI + + ++P + + NLI+ +L +P R
Sbjct: 222 RLPFQEANDSETLTKI--LDCKYSIPD--VLSDECRNLIQSMLVREPQKR 267
>At1g01140 [T] KOG0583 Serine/threonine protein kinase
Length = 447
Score = 114 bits (284), Expect = 8e-25
Identities = 99/361 (27%), Positives = 163/361 (44%), Gaps = 71/361 (19%)
Query: 13 AIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAI 72
A R NY + + +G+GSFA V + G AIK + R EI+
Sbjct: 11 ASRTRVGNYEMGRTLGEGSFAKVKYAKNTVTGDQAAIKILDREKVFRHKMVEQLKREIST 70
Query: 73 LKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+K IKHP++V +I+ + + Y+++E G+L F K + LK +
Sbjct: 71 MKLIKHPNVVEIIEVMASKTKIYIVLELVNGGEL--FDKIAQQGRLKEDEAR-------- 120
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
Y QQL +A+ + S+ + HRD+KP+NL +LD N
Sbjct: 121 --------------RYFQQLINAVDYCHSRGVYHRDLKPENL-----ILDANG------- 154
Query: 193 GFVGIYNLPILKIADFG---FARFLPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWS 248
+LK++DFG F+R + L T CG+P Y+APE+L+ + Y+ A AD+WS
Sbjct: 155 ---------VLKVSDFGLSAFSRQVREDGLLHTACGTPNYVAPEVLSDKGYDGAAADVWS 205
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
G +L+ + G PF N + L+++I KA E + P + +I+ +L +P +
Sbjct: 206 CGVILFVLMAGYLPFDEPNLMTLYKRICKA--EFSCPP--WFSQGAKRVIKRILEPNPIT 261
Query: 309 RMGFTDFFNNEVVTEDLTRYEQSYEP--------DLESKSKDVAESN---MFVSEYLVKP 357
R+ + +E +++ Y+P D+ D A SN V+E KP
Sbjct: 262 RISIAELLEDE-------WFKKGYKPPSFDQDDEDITIDDVDAAFSNSKECLVTEKKEKP 314
Query: 358 L 358
+
Sbjct: 315 V 315
>Hs4507273 [D] KOG0580 Serine/threonine protein kinase
Length = 275
Score = 112 bits (281), Expect = 2e-24
Identities = 79/296 (26%), Positives = 139/296 (46%), Gaps = 50/296 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
RL +++ + + +GKG F VY +A+K + +S EI I
Sbjct: 3 RLTVDDFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQA 62
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
++HP+I+ L + + YLI+EY G+L ++K + L
Sbjct: 63 HLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKL------------------ 104
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
+ +++++ AL + K ++HRDIKP+NLLL GF
Sbjct: 105 ------DEQRTATIIEEVADALTYCHDKKVIHRDIKPENLLL----------------GF 142
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
G +KIADFG++ P +T+CG+ Y+ PE++ + Y+ K DLW +G + Y
Sbjct: 143 RGE-----VKIADFGWSVHTPLPE-RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCY 196
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
E+ G PPF++++H E +++I K ++ P + + + +LI LL + P R+
Sbjct: 197 ELLVGYPPFESASHSETYRRILKV--DVRFPLSMPLGAR--DLISRLLRYQPLERL 248
>ECU03g0980 [T] KOG0583 Serine/threonine protein kinase
Length = 566
Score = 112 bits (281), Expect = 2e-24
Identities = 90/320 (28%), Positives = 137/320 (42%), Gaps = 56/320 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV------EIAIL 73
+Y K++G GS + V G +R G +AIK + R E+ I
Sbjct: 57 SYRFVKQLGTGSSSKVVLGRDVRSGEKVAIKIIPRRVNGGETGDMEMRCDQRVFREVIIS 116
Query: 74 KKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPP 133
+ HPHI L + + + ++LI EY +K R+ L + P
Sbjct: 117 SVLNHPHIARLKNFLYSPTHYFLIFEY---------VKGRQ-------LYDIIISSGPLK 160
Query: 134 STEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELG 193
E Y +QL SA+ ++ ++VHRD+K +N+L+ D ND
Sbjct: 161 EKEGQ--------RYFRQLLSAIDYIHRNSVVHRDLKIENILI-----DENDN------- 200
Query: 194 FVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTV 252
+K+ DFG + F N +L T CGS + APE+L Q+Y + D+WS+G V
Sbjct: 201 ---------VKLIDFGLSNFYDNKTLLNTFCGSLYFAAPELLQGQRYCGPEIDVWSLGVV 251
Query: 253 LYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGF 312
LY + CG PF + L KI A+ + I + LIRG++ P SRMG
Sbjct: 252 LYAILCGCVPFDDEDVQGLQAKIMDADFKFCKT----ISREAMELIRGMIVAQPSSRMGL 307
Query: 313 TDFFNNEVVTEDLTRYEQSY 332
+ +E V + SY
Sbjct: 308 SQVIGSEWVNKGQKSRINSY 327
>Hs6005850 [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 543
Score = 112 bits (280), Expect = 2e-24
Identities = 93/347 (26%), Positives = 146/347 (41%), Gaps = 71/347 (20%)
Query: 9 VVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXX-- 66
V KA+R + Y + K +G G+ V + + +AIK +S+
Sbjct: 211 VYPKALR---DEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPA 267
Query: 67 ---XVEIAILKKIKHPHIVGL---IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
EI ILKK+ HP I+ + D E D+Y+++E G+L F K N LK
Sbjct: 268 LNVETEIEILKKLNHPCIIKIKNFFDAE----DYYIVLELMEGGEL--FDKVVGNKRLKE 321
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
K Y Q+ A+++L ++HRD+KP+N+LL +
Sbjct: 322 ATCKL----------------------YFYQMLLAVQYLHENGIIHRDLKPENVLLSSQE 359
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL---NY 237
D ++KI DFG ++ L TSL TLCG+P Y+APE+L
Sbjct: 360 EDC------------------LIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGT 401
Query: 238 QKYNAKADLWSVGTVLYEMCCGRPPF-KASNHLELFQKIKKANDEITVPSNCYIEPKLFN 296
YN D WS+G +L+ G PPF + + L +I + K +
Sbjct: 402 AGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALD 461
Query: 297 LIRGLLTFDPDSRMGFTDFFNNEVVTEDLTRYEQSYEPDLESKSKDV 343
L++ LL DP +R TE+ R+ + D++ K +D+
Sbjct: 462 LVKKLLVVDPKARF----------TTEEALRHPWLQDEDMKRKFQDL 498
>CE28061 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28060 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 302
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28059 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 350
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28058 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 571
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28057 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 520
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28056 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 518
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28055 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28054 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 482
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28053 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 720
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>CE28051 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 559
Score = 112 bits (280), Expect = 2e-24
Identities = 78/293 (26%), Positives = 130/293 (43%), Gaps = 43/293 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY V++E+GKG+F+VV + + G A K ++ E I +K++
Sbjct: 9 SDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLER-EARICRKLQ 67
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + S YL+ + G+L I R E Y H
Sbjct: 68 HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 113
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ + S +VHRD+KP+NLLL +
Sbjct: 114 ----------CIQQILESIAYCHSNGIVHRDLKPENLLLASKAKG--------------- 148
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+K+ADFG A + ++ G+P Y++PE+L Y+ D+W+ G +LY +
Sbjct: 149 ---AAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILL 205
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ +LI +LT +P R+
Sbjct: 206 VGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRI 258
>7299536 [D] KOG0580 Serine/threonine protein kinase
Length = 411
Score = 112 bits (280), Expect = 2e-24
Identities = 82/291 (28%), Positives = 131/291 (44%), Gaps = 48/291 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
N+ + + +G+G F VY +A+K + + EI I ++HP
Sbjct: 153 NFDIGRLLGRGKFGNVYLAREKESQFVVALKVLFKRQIGESNVEHQVRREIEIQSHLRHP 212
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L YLI+EY G L N + P+ +
Sbjct: 213 HILRLYAYFHDDVRIYLILEYAPQGTLF-------NALQAQPMKR--------------- 250
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ Y+Q L SAL +L ++++HRDIKP+NLLL G G+
Sbjct: 251 FDERQSATYIQALCSALLYLHERDIIHRDIKPENLLL----------------GHKGV-- 292
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
LKIADFG++ PN S+ TLCG+ Y+ PE++ + + DLWS+G + +E+ G
Sbjct: 293 ---LKIADFGWSVHEPN-SMRMTLCGTVDYLPPEMVQGKPHTKNVDLWSLGVLCFELLVG 348
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PF + N+ E ++KI K + ++ +I +LI LL +P R+
Sbjct: 349 HAPFYSKNYDETYKKILKVDYKLPE----HISKAASHLISKLLVLNPQHRL 395
>7293666 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 576
Score = 112 bits (280), Expect = 2e-24
Identities = 85/302 (28%), Positives = 133/302 (43%), Gaps = 50/302 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+ Y + GKG FA Y+ + + A K VS+ EI I + + H
Sbjct: 23 KTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQEITIHRSLNH 82
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV + S + Y+++E C + K+RK++ T FE
Sbjct: 83 PNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSI--------TEFE---------- 124
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
Y+ Q+ +K+L ++HRD+K NL L ND
Sbjct: 125 ------CRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFL-------ND------------- 158
Query: 199 NLPILKIADFGFA-RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
L +KI DFG A R +TLCG+P Y+APEIL + ++ + D+WS+G V+Y +
Sbjct: 159 -LLHVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLL 217
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G+PPF+ + + KIKK E VPS Y+ +++ +L +P+SR N
Sbjct: 218 VGQPPFETKTLKDTYSKIKKC--EYRVPS--YLRKPAADMVIAMLQPNPESRPAIGQLLN 273
Query: 318 NE 319
E
Sbjct: 274 FE 275
>CE05780 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 336
Score = 112 bits (279), Expect = 3e-24
Identities = 81/306 (26%), Positives = 129/306 (41%), Gaps = 62/306 (20%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV---------- 68
+ Y + IGKG+F+ V+ DG A+K +S
Sbjct: 55 KQYEIGAIIGKGNFSSVHLTRRKEDGTKCALKVRYQSTLQFSFPSKFFQQVEKRAMRGKC 114
Query: 69 -----EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLI 123
E+ +L I+H HI+ +ID T + ++++ E+ GDL I+K + I
Sbjct: 115 FFVDNEVEMLSLIQHDHIISIIDAFSTENQYFIVFEHAQYGDLYETIRKNGRIEEPDAAI 174
Query: 124 KTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDY 183
T+ Q++SAL +L +N+VHRD+KP+NLLL
Sbjct: 175 ITL------------------------QVASALNYLHERNVVHRDVKPENLLLVDKFS-- 208
Query: 184 NDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAK 243
+K+ DFG A + +CG+P Y APE+L Y+ +
Sbjct: 209 -------------------VKLCDFGLACHILGPLYR--ICGTPTYCAPEVLRETGYSTR 247
Query: 244 ADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLT 303
D+WS+G VLY M G PF+A + LF+ I +A + +P I K +L+ L+
Sbjct: 248 CDIWSLGVVLYVMLVGYAPFRAPDQTRLFKLIMQAKPNLDMPEWKGISLKAKDLVSRLMN 307
Query: 304 FDPDSR 309
+ R
Sbjct: 308 KTEERR 313
>7296450 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 769
Score = 112 bits (279), Expect = 3e-24
Identities = 83/293 (28%), Positives = 132/293 (44%), Gaps = 49/293 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E+Y V+ +GKG FA VYK L +++AIK + + E+ I ++KH
Sbjct: 12 EDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKH 71
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P ++ L + ++ YL++E G+L ++ H P TE
Sbjct: 72 PSVLQLYTFFQDANYVYLVLELAHNGELHRYMN-----------------HIARPFTETE 114
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ L+Q+ + L +L S N++HRDI NLLL + H
Sbjct: 115 A------ASILKQVVAGLLYLHSHNIMHRDISLSNLLLS---------REMH-------- 151
Query: 199 NLPILKIADFGFARFLPNTSLAE-TLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+KIADFG A L T+CG+P Y++PE+++ + AD+WSVG +LY +
Sbjct: 152 ----VKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLL 207
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
GRPPF+ K+ E +P++ E + +LI LL P R+
Sbjct: 208 VGRPPFETDAVQSTLNKV--VMSEYIMPAHLSYEAQ--DLINKLLKKLPHERI 256
>Hs4758016 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 607
Score = 111 bits (278), Expect = 4e-24
Identities = 77/301 (25%), Positives = 131/301 (42%), Gaps = 50/301 (16%)
Query: 27 IGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGLID 86
+GKG FA Y+ G A+K + +S EI + + ++H HIV
Sbjct: 29 LGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSH 88
Query: 87 CERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLVV 146
+ + Y+ +E C+ L K R L+ P +
Sbjct: 89 HFEDADNIYIFLELCSRKSLAHIWKARHTLL--------------EPEVRY--------- 125
Query: 147 NYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKIA 206
YL+Q+ S LK+L + ++HRD+K N + + LK+
Sbjct: 126 -YLRQILSGLKYLHQRGILHRDLKLGNFFITENME---------------------LKVG 163
Query: 207 DFGFA-RFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKA 265
DFG A R P +T+CG+P Y+APE+L Q + +AD+WS+G V+Y + CG PPF+
Sbjct: 164 DFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFET 223
Query: 266 SNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEVVTEDL 325
++ E ++ IK+ + T+P++ + + L+ +L P R ++ T+
Sbjct: 224 ADLKETYRCIKQVH--YTLPASLSLPAR--QLLAAILRASPRDRPSIDQILRHDFFTKGY 279
Query: 326 T 326
T
Sbjct: 280 T 280
>CE21025 [D] KOG0580 Serine/threonine protein kinase
Length = 326
Score = 111 bits (278), Expect = 4e-24
Identities = 80/305 (26%), Positives = 145/305 (47%), Gaps = 48/305 (15%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+++ V + +GKG F V+ + R IA+K + ++ EI I ++H
Sbjct: 42 DDFDVGRPLGKGKFGNVFISREKKTKRIIALKVLFKTQLLQLGVSHQLKREIEIQYHLRH 101
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+I+ L ++I++Y + G+L N++ P K
Sbjct: 102 PNILTLYGYFHDDKRVFVILDYASRGELF-------NVLQSQPGHK-------------- 140
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+N V+ +++QL++AL + SK ++HRDIKP+NLLL + L
Sbjct: 141 -VNEVIAGRFVRQLANALHYCHSKGVIHRDIKPENLLLDSKLN----------------- 182
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LK+ADFG++ + + S TLCG+ Y+APE+++ Q ++ D+W++G +L+EM
Sbjct: 183 ----LKLADFGWS-VVADHSKRHTLCGTMDYLAPEMVSNQPHDFNVDIWAIGILLFEMLV 237
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PF +L +IK+ +I +PS + +LI ++ +P R+ D +
Sbjct: 238 GYAPFANQTGDKLIARIKEC--KIYIPS--VVTDGAASLINAIIKKEPQERLPLVDIMAH 293
Query: 319 EVVTE 323
+ E
Sbjct: 294 PWIKE 298
>At3g08720 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 471
Score = 111 bits (278), Expect = 4e-24
Identities = 86/294 (29%), Positives = 135/294 (45%), Gaps = 52/294 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E++ V K +G+G+F VY+ A+K + + E IL KI H
Sbjct: 138 EDFEVLKVVGQGAFGKVYQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDH 197
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P IV L +T YL++++ G L F + H
Sbjct: 198 PFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLY-------------------------HQ 232
Query: 139 GLNRV-LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
GL R L Y ++ SA+ L K ++HRD+KP+N+L+ G V
Sbjct: 233 GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVD-------------GHV-- 277
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+ DFG A+ + + ++CG+ YMAPEI+ + ++ AD WSVG +LYEM
Sbjct: 278 ------MLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEML 331
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
G+PPF S ++ QKI K D+I +P ++ + L++GLL +P+ R+G
Sbjct: 332 TGKPPFLGSKG-KIQQKIVK--DKIKLPQ--FLSNEAHALLKGLLQKEPERRLG 380
>Hs13569922 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 628
Score = 110 bits (276), Expect = 7e-24
Identities = 84/296 (28%), Positives = 129/296 (43%), Gaps = 54/296 (18%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + +GKG++ V K GR +AIK++ + EI I+ + HPH
Sbjct: 53 YEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ + + SS ++MEY + GDL +I +R+ L +
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSERE-------------------- 151
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
++ +Q+ SA+ + +VHRD+K +N+ LLD N
Sbjct: 152 ----ARHFFRQIVSAVHYCHQNRVVHRDLKLENI-----LLDANGN-------------- 188
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KIADFG + +T CGSPLY +PEI+N + Y + D WS+G +LY + G
Sbjct: 189 --IKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHG 246
Query: 260 RPPFKASNHLELFQKIKK-ANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
PF +H L ++I A E PS+ LIR LL +P R D
Sbjct: 247 TMPFDGHDHKILVKQISNGAYREPPKPSDA------CGLIRWLLMVNPTRRATLED 296
>CE15612 [T] KOG0690 Serine/threonine protein kinase
Length = 541
Score = 110 bits (276), Expect = 7e-24
Identities = 106/417 (25%), Positives = 171/417 (40%), Gaps = 66/417 (15%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX 60
M S + AK ++ E++ K +GKG+F V R + AIK + +
Sbjct: 173 MISIADTSEAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAR 232
Query: 61 XXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
E +L++ KHP + L + +M++ G+L ++K
Sbjct: 233 EEVAHTLTENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGT----- 287
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
+ P G VL + YL + ++V+RD+K +NLLL
Sbjct: 288 ---------FSEPRARFYGAEIVLALGYLHRC----------DIVYRDMKLENLLL---- 324
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFAR----FLPNTSLAETLCGSPLYMAPEILN 236
K H +KIADFG + F TS T CG+P Y+APE+L+
Sbjct: 325 -----DKDGH------------IKIADFGLCKEEISFGDKTS---TFCGTPEYLAPEVLD 364
Query: 237 YQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFN 296
Y D W VG V+YEM CGR PF + +H +LF+ I ++ PS E +
Sbjct: 365 DHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAG--DLRFPSKLSQEAR--T 420
Query: 297 LIRGLLTFDPDSRMGFTDFFNNEVVTEDLTR-------YEQSYEPDLESKSKDVAESNMF 349
L+ GLL DP R+G E+ D R Y + EP + + +++ F
Sbjct: 421 LLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYF 480
Query: 350 VSEYLVKPLKQQESAHIPPTQT-DENTSVQTGVRRTSGKERLATNHPPHQQIHPEDN 405
+E+ +P++ + T DE +Q+ + S + + + H+ EDN
Sbjct: 481 DNEFTSQPVQLTPPSRSGALATVDEQEEMQSNFTQFSFHNVMGSINRIHEA--SEDN 535
>At5g57630 [T] KOG0583 Serine/threonine protein kinase
Length = 412
Score = 110 bits (276), Expect = 7e-24
Identities = 92/331 (27%), Positives = 150/331 (44%), Gaps = 59/331 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + IG+G+FA V G +G +A+K + ++ EI +K + HP+
Sbjct: 12 YEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPN 71
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV + + T + ++MEY + G L+ + ++K +K + +F
Sbjct: 72 IVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQK---MKESDARKLF------------- 115
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
QQL A+ + ++ + HRD+KPQNLLL D K
Sbjct: 116 ---------QQLIDAVDYCHNRGVYHRDLKPQNLLL--------DSK------------- 145
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYN-AKADLWSVGTVLYEMCCG 259
LK++DFG + + + T CGSP Y+APE++ + Y+ A D+WS G +L+E+ G
Sbjct: 146 GNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYSGAAVDVWSCGVILFELLAG 205
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PPF L++KI +A + T P E K LI +L +P SR+ E
Sbjct: 206 YPPFDDHTLPVLYKKILRA--DYTFPPGFTGEQK--RLIFNILDPNPLSRITLA-----E 256
Query: 320 VVTED---LTRYEQSYEPDLESKSKDVAESN 347
++ +D Y Y +S +VAE N
Sbjct: 257 IIIKDSWFKIGYTPVYHQLSDSIKDNVAEIN 287
>Hs4885563 [T] KOG0694 Serine/threonine protein kinase
Length = 737
Score = 110 bits (275), Expect = 9e-24
Identities = 96/375 (25%), Positives = 158/375 (41%), Gaps = 73/375 (19%)
Query: 12 KAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIA 71
+A RL + ++ K +GKGSF V A+K + + E
Sbjct: 399 QAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKR 458
Query: 72 ILKKI-KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHY 130
IL KHP++ L C +T + +MEY GDL F I++ + +
Sbjct: 459 ILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRK--------------F 504
Query: 131 PPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFH 190
P + Y +++SAL FL +++RD+K N+LL D +
Sbjct: 505 DEPRSRF----------YAAEVTSALMFLHQHGVIYRDLKLDNILL--------DAEGH- 545
Query: 191 ELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSV 249
K+ADFG + + N T CG+P Y+APEIL +Y D W++
Sbjct: 546 ------------CKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWAL 593
Query: 250 GTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G ++YEM G+PPF+A N +LF+ I +D++ P ++ + ++++ +T +P R
Sbjct: 594 GVLMYEMMAGQPPFEADNEDDLFESI--LHDDVLYP--VWLSKEAVSILKAFMTKNPHKR 649
Query: 310 MGFTDFFNNEVVTE--------DLTRYEQ-SYEPDLESKSKDVAESNMF----------- 349
+G N E + D EQ +P + + K + N F
Sbjct: 650 LGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPVL 709
Query: 350 --VSEYLVKPLKQQE 362
V E +VK + Q+E
Sbjct: 710 TLVDEAIVKQINQEE 724
>Hs4759178 [D] KOG0580 Serine/threonine protein kinase
Length = 344
Score = 110 bits (275), Expect = 9e-24
Identities = 79/292 (27%), Positives = 136/292 (46%), Gaps = 50/292 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+++ + + +GKG F VY + +A+K + +S EI I + H
Sbjct: 75 DDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHH 134
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+I+ L + YLI+EY G+L + + +K+ T+ E
Sbjct: 135 PNILRLYNYFYDRRRIYLILEYAPRGEL--YKELQKSCTFDEQRTATIME---------- 182
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+L+ AL + K ++HRDIKP+NLLL G G
Sbjct: 183 ------------ELADALMYCHGKKVIHRDIKPENLLL----------------GLKGE- 213
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LKIADFG++ P+ +T+CG+ Y+ PE++ + +N K DLW +G + YE+
Sbjct: 214 ----LKIADFGWSVHAPSLR-RKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLV 268
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF++++H E +++I K ++ P++ + +LI LL +P R+
Sbjct: 269 GNPPFESASHNETYRRIVKV--DLKFPAS--VPTGAQDLISKLLRHNPSERL 316
>Hs4759052 [T] KOG0603 Ribosomal protein S6 kinase
Length = 809
Score = 110 bits (275), Expect = 9e-24
Identities = 109/417 (26%), Positives = 184/417 (43%), Gaps = 75/417 (17%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-HPHIV 82
+K +G+GSF++ K + + + + +K +S+ EI LK + HP+IV
Sbjct: 429 DKPLGEGSFSICRKCVHKKSNQALQVKIISKRMEANTQK------EITALKLCEGHPNIV 482
Query: 83 GLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNR 142
L + +L+ME G+L ++K+K+ TE + + R
Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFDALRKKKHF----------------SETEASYIMR 526
Query: 143 VLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPI 202
LV SAL + +VHRD+KP+NLL D ND NL I
Sbjct: 527 KLV--------SALSHMHDLGVVHRDLKPENLLFT----DEND-------------NLEI 561
Query: 203 LKIADFGFARFLP-NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRP 261
KI DFGFAR P + +T C + PE+LN Y+ DLWS+G +LY M G+
Sbjct: 562 -KIIDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDESCDLWSLGVILYTMLSGQV 620
Query: 262 PFKA-------SNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
PF++ ++ +E+ +KIKK + + + + +LI+GLLT DP+ R+ +
Sbjct: 621 PFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSG 680
Query: 315 FFNNEVVTEDLTRYEQS--YEPDLESKSKDVAESNMFVSEYLVKPLKQQ-------ESAH 365
NE + +D ++ + PD+ S + + + + K++ + A
Sbjct: 681 LRYNEWL-QDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREGFCLQNVDKAP 739
Query: 366 IPPTQTDENTSVQTGVRRTSGKERLATNHPPHQQIHPED--------NSQNPEQSYQ 414
+ + + TS T RR S + +++ H + P +S NPE +Q
Sbjct: 740 LAKRRKMKKTSTSTETRRGSSESSHSSSSHSHGKTTPTKTLQPSNPADSNNPETLFQ 796
Score = 68.6 bits (166), Expect = 4e-11
Identities = 77/312 (24%), Positives = 138/312 (43%), Gaps = 62/312 (19%)
Query: 13 AIRLPTENYSVEKEIGKGSFAVVY--KGLSLRD-GRNIAIKAVSRSXXXXXXXXXXXX-V 68
A ++ EN+ + K +G G++ V+ + +S D G+ A+K + ++
Sbjct: 41 AEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRT 100
Query: 69 EIAILKKIKH-PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVF 127
E +L+ I+ P +V L +T + +LI++Y G+L + +R+
Sbjct: 101 ERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERF----------- 149
Query: 128 EHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPK 187
TEH V Y+ ++ AL+ L +++RDIK +N+LL D N
Sbjct: 150 -------TEHE------VQIYVGEIVLALEHLHKLGIIYRDIKLENILL-----DSNGH- 190
Query: 188 TFHELGFVGIYNLPILKIADFGFAR--FLPNTSLAETLCGSPLYMAPEILNY--QKYNAK 243
+ + DFG ++ T A + CG+ YMAP+I+ ++
Sbjct: 191 ---------------VVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKA 235
Query: 244 ADLWSVGTVLYEMCCGRPPF----KASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
D WS+G ++YE+ G PF + ++ E+ ++I K+ E P K +LI+
Sbjct: 236 VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKS--EPPYPQEMSALAK--DLIQ 291
Query: 300 GLLTFDPDSRMG 311
LL DP R+G
Sbjct: 292 RLLMKDPKKRLG 303
>At2g45490 [D] KOG0580 Serine/threonine protein kinase
Length = 288
Score = 109 bits (273), Expect = 2e-23
Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 49/291 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
++ + + +GKG F VY + +A+K + + E+ I ++HP
Sbjct: 21 DFEIGRPLGKGKFGRVYLAREAKSKYIVALKVIFKEQIEKYKIHHQLRREMEIQTSLRHP 80
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+I+ L + +LI+EY G+L +K+ +L TE
Sbjct: 81 NILRLFGWFHDNERIFLILEYAHGGELYGVLKQNGHL------------------TEQQA 122
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
Y+ LS AL + K ++HRDIKP+NLLL HE
Sbjct: 123 ------ATYIASLSQALAYCHGKCVIHRDIKPENLLLD------------HE-------- 156
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
LKIADFG++ + +++ +T+CG+ Y+APE++ + ++ D W++G + YE G
Sbjct: 157 -GRLKIADFGWS--VQSSNKRKTMCGTLDYLAPEMVENRDHDYAVDNWTLGILCYEFLYG 213
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PPF+A + + F++I K + + N E K NLI LL DP R+
Sbjct: 214 NPPFEAESQKDTFKRILKIDLSFPLTPNVSEEAK--NLISQLLVKDPSKRL 262
>Hs4885061 [T] KOG0690 Serine/threonine protein kinase
Length = 480
Score = 109 bits (272), Expect = 2e-23
Identities = 98/374 (26%), Positives = 153/374 (40%), Gaps = 63/374 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R+ + K +GKG+F V GR A+K + + E +L+
Sbjct: 144 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQ 203
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+HP + L +T +MEY G+L F + + + VF
Sbjct: 204 NSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER-----------VFSE----- 247
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRS-KNLVHRDIKPQNLLLCTPLLDYNDPKTFHELG 193
+R Y ++ SAL +L S KN+V+RD+K +NL+L K H
Sbjct: 248 ------DRARF--YGAEIVSALDYLHSEKNVVYRDLKLENLML---------DKDGH--- 287
Query: 194 FVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTV 252
+KI DFG + + + + +T CG+P Y+APE+L Y D W +G V
Sbjct: 288 ---------IKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVV 338
Query: 253 LYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGF 312
+YEM CGR PF +H +LF+ I +EI P + P+ +L+ GLL DP R+G
Sbjct: 339 MYEMMCGRLPFYNQDHEKLFELI--LMEEIRFPRT--LGPEAKSLLSGLLKKDPKQRLGG 394
Query: 313 TDFFNNEVVTEDLTR-------YEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAH 365
E++ YE+ P + + ++ F E+ Q
Sbjct: 395 GSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTA-----QMITI 449
Query: 366 IPPTQTDENTSVQT 379
PP Q D V +
Sbjct: 450 TPPDQDDSMECVDS 463
>Hs20545357 [T] KOG0583 Serine/threonine protein kinase
Length = 436
Score = 109 bits (272), Expect = 2e-23
Identities = 87/318 (27%), Positives = 134/318 (41%), Gaps = 53/318 (16%)
Query: 5 SHDKVVAKAIRLPTEN--YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXX 62
S D+ V + I L Y + EIG G+F+ V G+ +AIK + ++
Sbjct: 56 SQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQ 115
Query: 63 XXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPL 122
EI+ ++K+ HP+I+ L + T S +L+MEY G+L F K L P
Sbjct: 116 RLLSR-EISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGEL--FGKISTEGKLSEPE 172
Query: 123 IKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLD 182
K +F Q+ SA+K + ++HRD+K +N+ +
Sbjct: 173 SKLIFS----------------------QIVSAVKHMHENQIIHRDLKAENVFYTSNTC- 209
Query: 183 YNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-N 241
+K+ DFGF+ + T CGSP Y APE+ + Y
Sbjct: 210 --------------------VKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIG 249
Query: 242 AKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGL 301
D+W++G +LY M G PF+A E K+KK+ E T ++ LIRG+
Sbjct: 250 IYVDIWALGVLLYFMVTGTMPFRA----ETVAKLKKSILEGTYSVPPHVSEPCHRLIRGV 305
Query: 302 LTFDPDSRMGFTDFFNNE 319
L P R G N+E
Sbjct: 306 LQQIPTERYGIDCIMNDE 323
>CE24761 [D] KOG0580 Serine/threonine protein kinase
Length = 305
Score = 109 bits (272), Expect = 2e-23
Identities = 80/298 (26%), Positives = 135/298 (44%), Gaps = 50/298 (16%)
Query: 12 KAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIA 71
K + ++ + + +GKG F VY + ++AIK + +S EI
Sbjct: 21 KGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIE 80
Query: 72 ILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYP 131
I + HP+I+ L + YL++EY G++ K L TV + +
Sbjct: 81 IQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMY------KQL--------TVSKRFS 126
Query: 132 PPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
P+ Y+ +++ AL + KN++HRDIKP+NLL+
Sbjct: 127 EPTA----------AKYMYEIADALSYCHRKNVIHRDIKPENLLI--------------- 161
Query: 192 LGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGT 251
G G LKI DFG++ P+ +T+CG+ Y+ PE++N ++ DLW++G
Sbjct: 162 -GSQGE-----LKIGDFGWSVHAPSNK-RQTMCGTMDYLPPEMVNGADHSDAVDLWAIGV 214
Query: 252 VLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
+ YE G+PPF+ + + + IK A T P + ++ +LI LL DP +R
Sbjct: 215 LCYEFLVGKPPFEHEDQSKTYAAIKAA--RFTYPDS--VKKGARDLIGRLLVVDPKAR 268
>Hs7661974 [T] KOG0583 Serine/threonine protein kinase
Length = 651
Score = 108 bits (271), Expect = 3e-23
Identities = 87/338 (25%), Positives = 152/338 (44%), Gaps = 59/338 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + + IG G FA V + G +AIK + ++ EI LK ++H H
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKT--EIEALKNLRHQH 68
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I L T++ ++++EYC G+L +I + L + + VF
Sbjct: 69 ICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEET--RVVF------------- 113
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+Q+ SA+ ++ S+ HRD+KP+NLL +H+L
Sbjct: 114 ---------RQIVSAVAYVHSQGYAHRDLKPENLLF----------DEYHKL-------- 146
Query: 201 PILKIADFGF-ARFLPNTSL-AETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMC 257
K+ DFG A+ N +T CGS Y APE++ + Y ++AD+WS+G +LY +
Sbjct: 147 ---KLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLM 203
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
CG PF N + L++KI + ++ ++ P L++ +L DP R+ + N
Sbjct: 204 CGFLPFDDDNVMALYKKIMRGKYDVPK----WLSPSSILLLQQMLQVDPKKRISMKNLLN 259
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLV 355
+ + +D +Y + +SK+ + + V+E V
Sbjct: 260 HPWIMQD-----YNYPVEWQSKNPFIHLDDDCVTELSV 292
>Hs5032091 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 431
Score = 108 bits (271), Expect = 3e-23
Identities = 81/294 (27%), Positives = 129/294 (43%), Gaps = 51/294 (17%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEI-AILKKIKHPHIVG 83
K IGKGSF V + A+K + + E +LK +KHP +VG
Sbjct: 102 KVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVG 161
Query: 84 LIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRV 143
L +T+ Y +++Y G+L + +++ + +
Sbjct: 162 LHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-------------------- 201
Query: 144 LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPIL 203
Y +++SAL +L S N+V+RD+KP+N+LL + +
Sbjct: 202 ----YAAEIASALGYLHSLNIVYRDLKPENILLDSQ---------------------GHI 236
Query: 204 KIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPP 262
+ DFG + + + S T CG+P Y+APE+L+ Q Y+ D W +G VLYEM G PP
Sbjct: 237 VLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPP 296
Query: 263 FKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFF 316
F + N E++ I N + + N I +L+ GLL D R+G D F
Sbjct: 297 FYSRNTAEMYDNI--LNKPLQLKPN--ITNSARHLLEGLLQKDRTKRLGAKDDF 346
>Hs4885549 [T] KOG0690 Serine/threonine protein kinase
Length = 479
Score = 108 bits (271), Expect = 3e-23
Identities = 96/378 (25%), Positives = 153/378 (40%), Gaps = 54/378 (14%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX 60
+ E D R ++ K +GKG+F V G+ A+K + +
Sbjct: 128 IGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAK 187
Query: 61 XXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
E +LK +HP + L +T +MEY G+L F + + +
Sbjct: 188 DEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRER------ 241
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
VF +R Y ++ SAL +L S +V+RD+K +NL+L
Sbjct: 242 -----VFSE-----------DRTRF--YGAEIVSALDYLHSGKIVYRDLKLENLML---- 279
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQK 239
K H +KI DFG + + + + +T CG+P Y+APE+L
Sbjct: 280 -----DKDGH------------IKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND 322
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
Y D W +G V+YEM CGR PF +H +LF+ I ++I P + K +L+
Sbjct: 323 YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI--LMEDIKFPRTLSSDAK--SLLS 378
Query: 300 GLLTFDPDSRMGFTDFFNNEVVTEDL---TRYEQSYEPDLESKSKDVAESNMFVSEYLVK 356
GLL DP+ R+G E++ ++ Y+ L K S + Y +
Sbjct: 379 GLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSET-DTRYFDE 437
Query: 357 PLKQQESAHIPPTQTDEN 374
Q PP + DE+
Sbjct: 438 EFTAQTITITPPEKYDED 455
>Hs4758192 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 414
Score = 108 bits (271), Expect = 3e-23
Identities = 93/369 (25%), Positives = 156/369 (42%), Gaps = 47/369 (12%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-HPHIVG 83
+E+G+G FAVV K + G+ A K + R EIA+L+ + +P ++
Sbjct: 65 RELGRGKFAVVRKCIKKDSGKEFAAKFM-RKRRKGQDCRMEIIHEIAVLELAQDNPWVIN 123
Query: 84 LIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRV 143
L + T+S+ L++EY A G+ +F+ E
Sbjct: 124 LHEVYETASEMILVLEYAAGGE--------------------IFDQCVADREE--AFKEK 161
Query: 144 LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCT--PLLDYNDPKTFHELGFVGIYNLP 201
V ++Q+ + FL ++++VH D+KPQN+LL + PL D
Sbjct: 162 DVQRLMRQILEGVHFLHTRDVVHLDLKPQNILLTSESPLGD------------------- 202
Query: 202 ILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRP 261
+KI DFG +R L N+ + G+P Y+APEIL+Y + D+WS+G + Y M G
Sbjct: 203 -IKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLTYVMLTGIS 261
Query: 262 PFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEVV 321
PF ++ E F I + N + + + IR LL P+ R + + +
Sbjct: 262 PFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAEECLKHPWL 321
Query: 322 TEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTSVQTGV 381
T+ + E S+ + + + + V E K + I + TS G
Sbjct: 322 TQSSIQ-EPSFRMEKALEEANALQEGHSVPEINSDTDKSETEESIVTEELIVVTSYTLGQ 380
Query: 382 RRTSGKERL 390
R S KE++
Sbjct: 381 CRQSEKEKM 389
>Hs19923468 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 878
Score = 108 bits (271), Expect = 3e-23
Identities = 74/240 (30%), Positives = 111/240 (45%), Gaps = 42/240 (17%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVG 83
++ +G G F VVY G + GR++A+K + + E+AIL+ ++HP IV
Sbjct: 554 DEVLGSGQFGVVYGGKHRKTGRDVAVKVIDKLRFPTKQESQLRN-EVAILQSLRHPGIVN 612
Query: 84 LIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRV 143
L T +++ME GD+ I S+E L
Sbjct: 613 LECMFETPEKVFVVMEKLH-GDMLEMIL----------------------SSEKGRLPER 649
Query: 144 LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPIL 203
L + Q+ AL+ L KN+VH D+KP+N+LL + DP P +
Sbjct: 650 LTKFLITQILVALRHLHFKNIVHCDLKPENVLLASA-----DP-------------FPQV 691
Query: 204 KIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPF 263
K+ DFGFAR + S ++ G+P Y+APE+L Q YN D+WSVG ++Y G PF
Sbjct: 692 KLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLLNQGYNRSLDMWSVGVIMYVSLSGTFPF 751
>CE25046 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 348
Score = 108 bits (271), Expect = 3e-23
Identities = 81/297 (27%), Positives = 129/297 (43%), Gaps = 46/297 (15%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRD-GRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
E Y +G G+F+ V+ S D G+ A+K + + EI +L+K++
Sbjct: 20 EKYDFRDVLGTGAFSKVFLAESKSDAGQMYAVKCIDKKALKGKEESLEN--EIKVLRKLR 77
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
H +IV L D YL+ME G+L I + + TE
Sbjct: 78 HNNIVQLFDTYDEKQFVYLVMELVTGGELFDRIVAKGSY------------------TEQ 119
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+ N ++Q+ A+ F+ +VHRD+KP+NLL YN +
Sbjct: 120 D------ASNLIRQVLEAVGFMHDNGVVHRDLKPENLLY------YNQDEDSK------- 160
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+ I+DFG ++ ++ + T CG+P Y+APE+L + Y D+WS+G + Y +
Sbjct: 161 -----IMISDFGLSK-TEDSGVMATACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILL 214
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
CG PPF + LF +I K E P I + I L+ DP++R D
Sbjct: 215 CGYPPFYDESDANLFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQD 271
>7300106 [T] KOG0690 Serine/threonine protein kinase
Length = 530
Score = 108 bits (271), Expect = 3e-23
Identities = 84/298 (28%), Positives = 128/298 (42%), Gaps = 50/298 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
++ EN+ K +GKG+F V + AIK + + E +LK
Sbjct: 179 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK 238
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
HP ++ L +T+ +M+Y G+L + + + +T F
Sbjct: 239 STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTED----RTRF------- 287
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
Y ++ SAL +L S+ +++RD+K +NLLL K H
Sbjct: 288 -------------YGAEIISALGYLHSQGIIYRDLKLENLLL---------DKDGH---- 321
Query: 195 VGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVL 253
+K+ADFG + + +T CG+P Y+APE+L+ Y D W G V+
Sbjct: 322 --------IKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVM 373
Query: 254 YEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
YEM CGR PF +H LF I +E+ P N E K NL+ GLL DP R+G
Sbjct: 374 YEMICGRLPFYNRDHDVLFTLI--LVEEVKFPRNITDEAK--NLLAGLLAKDPKKRLG 427
>Hs4507277_1 [R] KOG0589 Serine/threonine protein kinase
Length = 292
Score = 108 bits (271), Expect = 3e-23
Identities = 83/296 (28%), Positives = 135/296 (45%), Gaps = 49/296 (16%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
+P Y + +GKGS+ V RDG+ IK ++ E +L +
Sbjct: 1 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQ-EAQLLSQ 59
Query: 76 IKHPHIVGLIDC-ERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+KHP+IV + E Y++M +C GDL +K++K +L P
Sbjct: 60 LKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLL--------------PE 105
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
+ VV + Q++ AL++L K+++HRD+K QN+ L
Sbjct: 106 NQ--------VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLT----------------- 140
Query: 195 VGIYNLPILKIADFGFARFLPN-TSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVL 253
I+K+ D G AR L N +A TL G+P YM+PE+ + + YN K+D+W++G +
Sbjct: 141 ----RTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCV 196
Query: 254 YEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
YEM + F A + L +I ++ Y P+L LIR +L+ P+ R
Sbjct: 197 YEMATLKHAFNAKDMNSLVYRI--IEGKLPAMPRDY-SPELAELIRTMLSKRPEER 249
>SPBC106.10 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 512
Score = 108 bits (270), Expect = 3e-23
Identities = 82/297 (27%), Positives = 138/297 (45%), Gaps = 50/297 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R ++++ + +G GSF V+ S + AIK + + E IL
Sbjct: 195 RYGIQDFNFLQTLGTGSFGRVHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILS 254
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+++HP I L + + + +++M++ G+L ++K +P
Sbjct: 255 RVQHPFITILWGTFQDAKNLFMVMDFAEGGELFSLLRK--------------CHRFPEKV 300
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
+ Y ++ AL +L +V+RD+KP+NLLL + H
Sbjct: 301 AKF----------YAAEVILALDYLHHNQIVYRDLKPENLLL---------DRFGH---- 337
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
LKI DFGFA+ + +TS TLCG+P Y+APEI++ + YN AD WS+G +++
Sbjct: 338 --------LKIVDFGFAKRV-STSNCCTLCGTPDYLAPEIISLKPYNKAADWWSLGILIF 388
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
EM G PPF + N ++L++ I + ++ PS Y P +L+ LL D R G
Sbjct: 389 EMLAGYPPFYSENPMKLYENILEG--KVNYPS--YFSPASIDLLSHLLQRDITCRYG 441
>HsM4826916 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 108 bits (270), Expect = 3e-23
Identities = 81/298 (27%), Positives = 143/298 (47%), Gaps = 52/298 (17%)
Query: 27 IGKGSFAVVYKGLSLRDGRNI-AIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGLI 85
+GKG FA ++ +S D + + A K V +S +EI+I + + H H+VG
Sbjct: 59 LGKGGFAKCFE-ISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFH 117
Query: 86 DCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLV 145
+ ++++E C +R++L+ H K + E P +
Sbjct: 118 GFFEDNDFVFVVLELC----------RRRSLLEPHKRRKALTE----PEARY-------- 155
Query: 146 VNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKI 205
YL+Q+ ++L ++HRD+K NL L L +KI
Sbjct: 156 --YLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLE---------------------VKI 192
Query: 206 ADFGFARFLP-NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
DFG A + + +TLCG+P Y+APE+L+ ++++ + D+WS+G ++Y + G+PPF+
Sbjct: 193 GDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKEHSFEVDVWSIGCIMYTLLVGKPPFE 252
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEVVT 322
S E + +IKK +E ++P +I P +LI+ +L DP +R + N+E T
Sbjct: 253 TSCLKETYLRIKK--NEYSIPK--HINPVAASLIQKMLQTDPTARPTINELLNDEFFT 306
>Hs7706286 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 489
Score = 108 bits (270), Expect = 3e-23
Identities = 82/294 (27%), Positives = 126/294 (41%), Gaps = 44/294 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
TE Y + +E+GKG+F+VV + + + G+ A K ++ E I + +K
Sbjct: 10 TEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER-EARICRLLK 68
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D YLI + G+L I R E+Y H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAR--------------EYYSEADASH 114
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ A+ +VHRD+KP+NLLL + L
Sbjct: 115 ----------CIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKG--------------- 149
Query: 198 YNLPILKIADFGFARFLPNTSLAET-LCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+K+ADFG A + A G+P Y++PE+L Y DLW+ G +LY +
Sbjct: 150 ---AAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYIL 206
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+Q+IK + P + P+ +LI +LT +P R+
Sbjct: 207 LVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRI 260
>Hs4502557 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 473
Score = 108 bits (270), Expect = 3e-23
Identities = 78/291 (26%), Positives = 134/291 (45%), Gaps = 48/291 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
+ VE E+G+G+ ++VY+ + A+K + ++ EI +L ++ HP+
Sbjct: 46 FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRT-----EIGVLLRLSHPN 100
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ L + T ++ L++E G+L I ++ +Y +E +
Sbjct: 101 IIKLKEIFETPTEISLVLELVTGGELFDRIVEKG--------------YY----SERDAA 142
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ V +Q+ A+ +L +VHRD+KP+NLL TP D
Sbjct: 143 DAV------KQILEAVAYLHENGIVHRDLKPENLLYATPAPDAP---------------- 180
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGR 260
LKIADFG ++ + + L +T+CG+P Y APEIL Y + D+WSVG + Y + CG
Sbjct: 181 --LKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGF 238
Query: 261 PPFKASNHLE-LFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PF + +F++I P + +L+R L+ DP R+
Sbjct: 239 EPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRL 289
>At5g12180 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 528
Score = 108 bits (270), Expect = 3e-23
Identities = 84/331 (25%), Positives = 140/331 (41%), Gaps = 44/331 (13%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-H 78
+YS+ KE+G+G F V + G A K +++ E+ I+ +
Sbjct: 72 SYSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKRKLVNKEDIEDVRREVQIMHHLTGQ 131
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV L +L+ME CA G+L ++ K HY +
Sbjct: 132 PNIVELKGAYEDKHSVHLVMELCAGGELF------DRIIAKG--------HYSERAA--- 174
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ L+ + + S ++HRD+KP+N LL D N P
Sbjct: 175 -------ASLLRTIVQIVHTCHSMGVIHRDLKPENFLLLNK--DENSP------------ 213
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LK DFG + F + + + GS Y+APE+L +KY +AD+WS+G +LY + C
Sbjct: 214 ----LKATDFGLSVFYKPGEVFKDIVGSAYYIAPEVLK-RKYGPEADIWSIGVMLYILLC 268
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PPF A + +F I + + + + I P+ +L++ +L DP R+ N+
Sbjct: 269 GVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDLVKKMLNSDPKQRLTAAQVLNH 328
Query: 319 EVVTEDLTRYEQSYEPDLESKSKDVAESNMF 349
+ ED + + + S+ K N F
Sbjct: 329 PWIKEDGEAPDVPLDNAVMSRLKQFKAMNNF 359
>At1g61950 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 547
Score = 108 bits (270), Expect = 3e-23
Identities = 81/348 (23%), Positives = 144/348 (41%), Gaps = 46/348 (13%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK- 77
E YS+ +E+G+G F + Y + G+N A K++ + EI I+ +
Sbjct: 96 EKYSLGRELGRGQFGITYICTEISSGKNFACKSILKRKLIRTKDREDVRREIQIMHYLSG 155
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
P+IV + +L+ME C G+L I KR HY +
Sbjct: 156 QPNIVEIKGAYEDRQSVHLVMELCEGGELFDKITKRG--------------HYSEKAA-- 199
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
++ + ++ ++HRD+KP+N LL + D +
Sbjct: 200 --------AEIIRSVVKVVQICHFMGVIHRDLKPENFLLSS-----KDEAS--------- 237
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+LK DFG + F+ + E + GS Y+APE+L + Y D+WS G +LY +
Sbjct: 238 ---SMLKATDFGVSVFIEEGKVYEDIVGSAYYVAPEVLK-RNYGKAIDIWSAGVILYILL 293
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
CG PPF A +F++I + + I +L+R +L +DP R
Sbjct: 294 CGNPPFWAETDKGIFEEILRGEIDFESEPWPSISESAKDLVRNMLKYDPKKRFTAAQVLE 353
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDVAESN---MFVSEYLVKPLKQQE 362
+ + E ++ + + S+ K + N +++ + LK++E
Sbjct: 354 HPWIREGGEASDKPIDSAVLSRMKQLRAMNKLKKLAFKFIAQNLKEEE 401
>SPCC24B10.07 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 569
Score = 107 bits (268), Expect = 6e-23
Identities = 82/297 (27%), Positives = 134/297 (44%), Gaps = 50/297 (16%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
L + + + K +GKGSF V + R A+K + ++ E +L +
Sbjct: 225 LTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQ 284
Query: 76 IKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPST 135
+ +P IV L ++ YL++ + G+L +++ + F+ Y
Sbjct: 285 VNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQR-----------EGCFDTYRAKF- 332
Query: 136 EHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFV 195
Y+ +L AL+ L N+++RD+KP+N+LL DY T H
Sbjct: 333 ------------YIAELLVALECLHEFNVIYRDLKPENILL-----DY----TGH----- 366
Query: 196 GIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
+ + DFG + + T T CG+P Y+APE+L Y D W++G +LY
Sbjct: 367 -------IALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLY 419
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
EM G PPF N E+++KI D + P N I+ K +L+ GLLT P+ R+G
Sbjct: 420 EMITGLPPFYDENINEMYRKI--LQDPLRFPDN--IDEKAKDLLSGLLTRAPEKRLG 472
>At5g19360 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 523
Score = 107 bits (268), Expect = 6e-23
Identities = 84/331 (25%), Positives = 139/331 (41%), Gaps = 44/331 (13%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-H 78
+Y++ KE+G+G F V + G A K +++ E+ I+ +
Sbjct: 67 SYTLGKELGRGQFGVTHLCTQKATGLQFACKTIAKRKLVNKEDIEDVRREVQIMHHLTGQ 126
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV L +L+ME CA G+L ++ K HY +
Sbjct: 127 PNIVELKGAYEDKHSVHLVMELCAGGELF------DRIIAKG--------HYSERAA--- 169
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ L+ + + S ++HRD+KP+N LL + D N P
Sbjct: 170 -------ASLLRTIVQIIHTCHSMGVIHRDLKPENFLLLSK--DENSP------------ 208
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
LK DFG + F + + + GS Y+APE+L +KY +AD+WS+G +LY + C
Sbjct: 209 ----LKATDFGLSVFYKPGEVFKDIVGSAYYIAPEVLR-RKYGPEADIWSIGVMLYILLC 263
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
G PPF A + +F I + + I P+ +L+R +L DP R+ N+
Sbjct: 264 GVPPFWAESENGIFNAILSGQVDFSSDPWPVISPQAKDLVRKMLNSDPKQRLTAAQVLNH 323
Query: 319 EVVTEDLTRYEQSYEPDLESKSKDVAESNMF 349
+ ED + + + S+ K N F
Sbjct: 324 PWIKEDGEAPDVPLDNAVMSRLKQFKAMNNF 354
>7301213 [R] KOG0589 Serine/threonine protein kinase
Length = 841
Score = 107 bits (268), Expect = 6e-23
Identities = 70/260 (26%), Positives = 117/260 (44%), Gaps = 43/260 (16%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
NY + +G+GSF + DG I K ++ S E+ + K+ HP
Sbjct: 104 NYEKVRVVGQGSFGIAILYRRKSDGHQIVFKQINLSELSPPGRDLAMN-EVDVFSKLHHP 162
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV + + + MEY G L I +R+ + H+P
Sbjct: 163 NIVSYLGSFIKDNTLLIEMEYADGGTLAQIIAERQGKL-----------HFPER------ 205
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
++ +Q+SSA+ ++ S+N++HRD+K N+ L
Sbjct: 206 ----YIIAVFEQISSAINYMHSENILHRDLKTANVFL---------------------NR 240
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
I+KI DFG ++ + A+T+ G+P Y +PE+ ++Y+ K+D+W++G +L EMCC
Sbjct: 241 RGIVKIGDFGISKIMNTKIHAQTVLGTPYYFSPEMCEGKEYDNKSDIWALGCILGEMCCL 300
Query: 260 RPPFKASNHLELFQKIKKAN 279
+ F ASN EL KI N
Sbjct: 301 KKTFAASNLSELVTKIMAGN 320
>7299322 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 434
Score = 107 bits (268), Expect = 6e-23
Identities = 79/309 (25%), Positives = 134/309 (42%), Gaps = 59/309 (19%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
+ + K++G+G++ V G++ G+ +AIK + + E+ I+ + HP+
Sbjct: 82 FDIIKKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPN 141
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ + + L+ME+ A G+L ++ +RK VL + +F
Sbjct: 142 IIHIYEVFENREKMVLVMEFAAGGELYDYLSERK--VLTEEEARRIF------------- 186
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+Q+++A+ + + HRD+K +N+LL E G
Sbjct: 187 ---------RQVATAVYYCHKHKICHRDLKLENILL-------------DEKGNA----- 219
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
KIADFG + + L T CGSPLY +PEI+ Y + D WS+G +LY + G
Sbjct: 220 ---KIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYG 276
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEP----KLFNLIRGLLTFDPDSRMGFTDF 315
PF SN L ++I + + Y EP + LIR +LT P R
Sbjct: 277 SMPFDGSNFKRLVKQISQGD---------YYEPRKPSRASTLIRDMLTVCPRKRASIEQI 327
Query: 316 FNNEVVTED 324
++ V E+
Sbjct: 328 CSHWWVNEN 336
>SPAC19E9.02 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 722
Score = 107 bits (267), Expect = 8e-23
Identities = 88/317 (27%), Positives = 150/317 (46%), Gaps = 35/317 (11%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E Y + + IG GSF +YK L+DG +A K + E+ IL+ +KH
Sbjct: 2 EKYKILECIGHGSFGRIYKVQRLKDGALLAQKEIHFGNITRQEKQYIAD-EVNILRNLKH 60
Query: 79 PHIVGLI--DCERTSSDFYLIMEYCALGDLTFFI---KKRKNLVLKHPLIKTVFEHYPPP 133
P+IV + R++ L MEYC GDL I K+ K + ++K +
Sbjct: 61 PNIVQYCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLAL 120
Query: 134 STEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELG 193
H G N + + F ++++HRDIKP N+ L D N+
Sbjct: 121 YRCHYGENAPACDSQWPREI----FHPKQSVLHRDIKPANIFL-----DENNS------- 164
Query: 194 FVGIYNLPILKIADFGFARFLPNTSL-AETLCGSPLYMAPEILNYQKYNAKADLWSVGTV 252
+K+ DFG ++ L NT + ++ G+P YM+PEI+ Y+AK+D+W++G V
Sbjct: 165 ---------VKLGDFGLSKLLDNTRVFTQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCV 215
Query: 253 LYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGF 312
++E+C PF+ ++LEL + I + N ++ + Y + +F LIR L + D R
Sbjct: 216 IFEICMLTHPFEGRSYLELQRNICQGN--LSCWDHHYSD-DVFLLIRHCLEVNSDLRPTT 272
Query: 313 TDFFNNEVVTEDLTRYE 329
+ ++++ ++ E
Sbjct: 273 YQLLRSPILSDIRSKLE 289
>Hs4506737 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 107 bits (267), Expect = 8e-23
Identities = 92/354 (25%), Positives = 158/354 (43%), Gaps = 57/354 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVY---KGLSLRDGRNIAIKAVSRSXXXXXXXXXXXX-VEI 70
++ E + + + +GKG + V+ K G+ A+K + ++ E
Sbjct: 85 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAER 144
Query: 71 AILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHY 130
IL+++KHP IV LI +T YLI+EY + G+L F +R+ + ++
Sbjct: 145 NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL-FMQLEREGIFMEDT--------- 194
Query: 131 PPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFH 190
YL ++S AL L K +++RD+KP+N++L +
Sbjct: 195 --------------ACFYLAEISMALGHLHQKGIIYRDLKPENIML-------------N 227
Query: 191 ELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSV 249
G V K+ DFG + + + ++ T CG+ YMAPEIL +N D WS+
Sbjct: 228 HQGHV--------KLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSL 279
Query: 250 GTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G ++Y+M G PPF N + KI K ++ +P Y+ + +L++ LL + SR
Sbjct: 280 GALMYDMLTGAPPFTGENRKKTIDKILKC--KLNLPP--YLTQEARDLLKKLLKRNAASR 335
Query: 310 MGFTDFFNNEVVTEDLTR---YEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQ 360
+G EV R +E+ +E K + +S VS++ K +Q
Sbjct: 336 LGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQ 389
>7302860 [T] KOG0696 Serine/threonine protein kinase
Length = 679
Score = 107 bits (267), Expect = 8e-23
Identities = 88/313 (28%), Positives = 135/313 (43%), Gaps = 51/313 (16%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXX 60
M S+++ +K + +++ K +GKGSF V AIK + +
Sbjct: 330 MRSDTNTHTSSKKDMIRATDFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQD 389
Query: 61 XXXXXXXVEIAILKK-IKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLK 119
+E +L K P +V L C +T + +MEY GDL F I++
Sbjct: 390 DDVECTMIEKRVLALGEKPPFLVQLHSCFQTMDRLFFVMEYVNGGDLMFQIQQ------- 442
Query: 120 HPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTP 179
F + P + V Y ++++ L FL +K +++RD+K N+LL
Sbjct: 443 -------FGKFKEP----------VAVFYAAEIAAGLFFLHTKGILYRDLKLDNVLLDAD 485
Query: 180 LLDYNDPKTFHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQ 238
G V KIADFG + + +T CG+P Y+APEI+ YQ
Sbjct: 486 -------------GHV--------KIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQ 524
Query: 239 KYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLI 298
Y D W+ G +LYEM G+PPF + ELF I N ++ P + E K
Sbjct: 525 PYGKSVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHN--VSYPKSLSKEAK--EAC 580
Query: 299 RGLLTFDPDSRMG 311
+G LT P+ R+G
Sbjct: 581 KGFLTKQPNKRLG 593
>Hs4758194 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 372
Score = 107 bits (266), Expect = 1e-22
Identities = 79/302 (26%), Positives = 133/302 (43%), Gaps = 47/302 (15%)
Query: 14 IRLPTENYS-----VEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV 68
I + EN++ KE+G+G FAVV + +S G+ A K + +
Sbjct: 21 IPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILH- 79
Query: 69 EIAILKKIKH-PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVF 127
EIA+L+ K P ++ L + +S+ LI+EY A G+ +F
Sbjct: 80 EIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGE--------------------IF 119
Query: 128 EHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPK 187
P E N V + ++Q+ + +L N+VH D+KPQN+LL +
Sbjct: 120 SLCLPELAEMVSENDV--IRLIKQILEGVYYLHQNNIVHLDLKPQNILLSS--------- 168
Query: 188 TFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLW 247
IY L +KI DFG +R + + + G+P Y+APEILNY D+W
Sbjct: 169 ---------IYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMW 219
Query: 248 SVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPD 307
++G + Y + PF ++ E + I + N + + + + + I+ LL +P+
Sbjct: 220 NIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPE 279
Query: 308 SR 309
R
Sbjct: 280 KR 281
>Hs21359873 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 603
Score = 107 bits (266), Expect = 1e-22
Identities = 81/298 (27%), Positives = 138/298 (46%), Gaps = 52/298 (17%)
Query: 27 IGKGSFAVVYKGLSLRDGRNI-AIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGLI 85
+GKG FA ++ +S D + + A K V +S +EI+I + + H H+VG
Sbjct: 59 LGKGGFAKCFE-ISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFH 117
Query: 86 DCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLV 145
+ ++++E C L K+RK L P +
Sbjct: 118 GFFEDNDFVFVVLELCRRRSLLELHKRRKALT--------------EPEARY-------- 155
Query: 146 VNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKI 205
YL+Q+ ++L ++HRD+K NL L L +KI
Sbjct: 156 --YLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLE---------------------VKI 192
Query: 206 ADFGFARFLP-NTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
DFG A + + +TLCG+P Y+APE+L+ + ++ + D+WS+G ++Y + G+PPF+
Sbjct: 193 GDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFE 252
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNEVVT 322
S E + +IKK +E ++P +I P +LI+ +L DP +R + N+E T
Sbjct: 253 TSCLKETYLRIKK--NEYSIPK--HINPVAASLIQKMLQTDPTARPTINELLNDEFFT 306
>CE29092 [T] KOG0694 Serine/threonine protein kinase
Length = 707
Score = 107 bits (266), Expect = 1e-22
Identities = 87/314 (27%), Positives = 143/314 (44%), Gaps = 57/314 (18%)
Query: 2 SSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRN--IAIKAVSRSXXXX 59
SS S KV + + +++ K +GKGSF V L+ R G + AIK + +
Sbjct: 361 SSRSASKVPGGTLSI--HDFTFMKVLGKGSFGKVM--LAERKGTDEVYAIKILKKDVIVQ 416
Query: 60 XXXXXXXXVEIAILK-KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVL 118
E IL KHP + L +TS + +MEY GDL F I++ +
Sbjct: 417 DDDVECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRAR---- 472
Query: 119 KHPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCT 178
K + F Y +++ AL+FL ++++RD+K N+LL
Sbjct: 473 KFDESRARF--------------------YAAEVTCALQFLHRNDVIYRDLKLDNILL-- 510
Query: 179 PLLDYNDPKTFHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNY 237
D + ++ADFG + + +L T CG+P Y+APEIL
Sbjct: 511 ------DAEGH-------------CRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQE 551
Query: 238 QKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNL 297
+Y D W++G ++YEM G+PPF+A N +LF+ I ND++ P ++ + N+
Sbjct: 552 MEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAI--LNDDVLYP--VWLSKEAVNI 607
Query: 298 IRGLLTFDPDSRMG 311
++ +T + R+G
Sbjct: 608 LKAFMTKNAGKRLG 621
>CE28479 [T] KOG0583 Serine/threonine protein kinase
Length = 822
Score = 107 bits (266), Expect = 1e-22
Identities = 83/290 (28%), Positives = 130/290 (44%), Gaps = 51/290 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y V + IGKG+FA V +AIK++ S E+ I+K I HPH
Sbjct: 16 YDVGRAIGKGNFATVRIARHKIAKTKVAIKSIDVSALDRENLIKLER-EVKIVKVIDHPH 74
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV + R + Y++ EYC+ G+L + L+ K + + V
Sbjct: 75 IVKSYEIMRVDNMLYIVSEYCSSGEL------YETLIEKGRVAENVAR------------ 116
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ + +SA+ +L S+ +VHRD+K +N+LL K +
Sbjct: 117 ------KWFSETASAVAYLHSQGIVHRDLKAENILL---------GKNSN---------- 151
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
+KI DFGF+ F L T CGSP Y APE+L Y+ KAD+WS+G +LY + G
Sbjct: 152 --IKIIDFGFSNFQTGDQLLNTWCGSPPYAAPELLLGNSYDGMKADIWSMGVLLYILVAG 209
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
PF + + K+K++ V ++ + + IR +L +P R
Sbjct: 210 GFPFPSDS----VNKLKRSVLSGLVKIPYWVSVECADFIRKMLVLNPGKR 255
>CE15473 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 359
Score = 107 bits (266), Expect = 1e-22
Identities = 86/342 (25%), Positives = 154/342 (44%), Gaps = 59/342 (17%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGL 84
K +G GSF V + G A+K + + E IL+ I P +V +
Sbjct: 56 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 115
Query: 85 IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVL 144
+ +S+ Y+++E+ + G++ +++ H
Sbjct: 116 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRF--------------------- 154
Query: 145 VVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILK 204
Y Q+ A ++L S +L++RD+KP+NLL+ G+ LK
Sbjct: 155 ---YAAQIVLAFEYLHSLDLIYRDLKPENLLI-------------DSTGY--------LK 190
Query: 205 IADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
I DFGFA+ + + TLCG+P Y+APEI+ + YN D W++G ++YEM G PPF
Sbjct: 191 ITDFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 248
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM-----GFTDFFNNE 319
A +++++KI + ++ PS + +L +L++ LL D R G D N++
Sbjct: 249 ADQPIQIYEKI--VSGKVKFPS--HFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHK 304
Query: 320 VV--TEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLK 359
T+ + Y++ E K + +++ F +Y +PL+
Sbjct: 305 WFGSTDWIAIYQKKIEAPFLPKCRGPGDASNF-DDYEEEPLR 345
>CE04603 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 371
Score = 107 bits (266), Expect = 1e-22
Identities = 83/316 (26%), Positives = 147/316 (46%), Gaps = 59/316 (18%)
Query: 1 MSSESHDKVVAKAIRLPTENYSVEK-----EIGKGSFAVVYKGLSLRDGRNIAIKAVSRS 55
++ E+H K+ R E++S+ + IGKG+F V G + A+K ++
Sbjct: 41 LAEETHMKLSITPTR---ESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIR 97
Query: 56 XXXXXXXXXXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKN 115
E +L ++KHP IV + E+ S+ Y+IME+ G++ +++ ++
Sbjct: 98 RVVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRS 157
Query: 116 LVLKHPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLL 175
N + R Y ++ AL+++ S +V+RD+KP+NL+
Sbjct: 158 F--------------------SNSMARF----YASEIVCALEYIHSLGIVYRDLKPENLM 193
Query: 176 LCTPLLDYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL 235
L K H +K+ADFGFA+ L + + T+CG+P Y+APE L
Sbjct: 194 LS---------KEGH------------IKMADFGFAKELRDRTY--TICGTPDYLAPESL 230
Query: 236 NYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLF 295
+N D W++G ++YEM G+PPF+ E++ I ++ P + + K
Sbjct: 231 ARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAI--IEHKLKFPRSFNLAAK-- 286
Query: 296 NLIRGLLTFDPDSRMG 311
+L++ LL D R+G
Sbjct: 287 DLVKKLLEVDRTQRIG 302
>SPBC4F6.06 [T] KOG0583 Serine/threonine protein kinase
Length = 891
Score = 106 bits (265), Expect = 1e-22
Identities = 88/335 (26%), Positives = 130/335 (38%), Gaps = 68/335 (20%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEI--------- 70
NY + K IG GS V L+ G AIK V+R E
Sbjct: 124 NYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEATKAAQSEKN 183
Query: 71 ---------AILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHP 121
A+ ++HP+I D T+S +Y++ E+ G + +I
Sbjct: 184 KEIRTVREAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYI----------- 232
Query: 122 LIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLL 181
H L +++Q+ SAL +L ++VHRD+K +N+L+
Sbjct: 233 -------------ISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILIS---- 275
Query: 182 DYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY- 240
KT +KI DFG + S T CGS + APE+LN Q Y
Sbjct: 276 -----KTGD------------IKIIDFGLSNLYRRQSRLRTFCGSLYFAAPELLNAQPYI 318
Query: 241 NAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRG 300
+ D+WS G VLY + CG+ PF N L KIKK TV Y+ L+
Sbjct: 319 GPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKG----TVEYPSYLSSDCKGLLSR 374
Query: 301 LLTFDPDSRMGFTDFFNNEVVTEDLTRYEQSYEPD 335
+L DP R + N+ + + S+ P+
Sbjct: 375 MLVTDPLKRATLEEVLNHPWMIRNYEGPPASFAPE 409
>CE18967 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 1101
Score = 106 bits (265), Expect = 1e-22
Identities = 67/240 (27%), Positives = 113/240 (46%), Gaps = 42/240 (17%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVG 83
E+ +G G F VY G+ R+G+++A+K + + E+ IL+K+ HP +V
Sbjct: 773 EEVLGSGQFGTVYGGIHRRNGQHVAVKLIDK-LKFPPNKEDLLRAEVQILEKVDHPGVVH 831
Query: 84 LIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRV 143
+ T+ +++ME LK +++ + S+E L+
Sbjct: 832 FMQMLETTDRIFVVMEK-----------------LKGDMLEMIL------SSEKGRLSER 868
Query: 144 LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPIL 203
+ Q+ AL++L N+VH D+KP+N+LL N F P +
Sbjct: 869 TTQFLVAQILEALRYLHHLNIVHCDLKPENILL-------NSNSDF-----------PQV 910
Query: 204 KIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPF 263
K+ DFGFAR + S ++ G+P Y+APE+L + +N D+WSVG ++Y G PF
Sbjct: 911 KLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGFNRSLDMWSVGVIVYVSLSGTFPF 970
>SPCC18B5.11c [D] KOG0615 Serine/threonine protein kinase Chk2 and related
proteins
Length = 460
Score = 106 bits (264), Expect = 2e-22
Identities = 83/308 (26%), Positives = 133/308 (42%), Gaps = 56/308 (18%)
Query: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV----E 69
I+ +Y + + +G G+FAVV + + G+ AIK +++ E
Sbjct: 160 IKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQRE 219
Query: 70 IAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEH 129
I ILK + HP +V + + +++MEY GDL F+
Sbjct: 220 IDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLMDFL------------------- 260
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTF 189
+ ++ L+QL L L + + HRDIKP+N+L+ ND F
Sbjct: 261 -----IANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILIT------ND---F 306
Query: 190 HELGFVGIYNLPILKIADFGFARFLPNT-SLAETLCGSPLYMAPEILNYQK------YNA 242
H LKI+DFG A+ + T + ET CG+ Y+APE+L + Y+
Sbjct: 307 H------------LKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDD 354
Query: 243 KADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLL 302
K D+WS+G VLY M PF +S+ + + I K I I + +LI +L
Sbjct: 355 KVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRML 414
Query: 303 TFDPDSRM 310
+P+ R+
Sbjct: 415 EINPEKRI 422
>Hs4506075 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 912
Score = 106 bits (264), Expect = 2e-22
Identities = 69/240 (28%), Positives = 110/240 (45%), Gaps = 42/240 (17%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVG 83
++ +G G F +VY G + GR++AIK + + E+AIL+ + HP +V
Sbjct: 586 DEVLGSGQFGIVYGGKHRKTGRDVAIKIIDKLRFPTKQESQLRN-EVAILQNLHHPGVVN 644
Query: 84 LIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRV 143
L T +++ME L + K + +H + +
Sbjct: 645 LECMFETPERVFVVMEKLHGDMLEMILSSEKGRLPEH-------------------ITKF 685
Query: 144 LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPIL 203
L+ Q+ AL+ L KN+VH D+KP+N+LL + DP P +
Sbjct: 686 LIT----QILVALRHLHFKNIVHCDLKPENVLLASA-----DP-------------FPQV 723
Query: 204 KIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPF 263
K+ DFGFAR + S ++ G+P Y+APE+L + YN D+WSVG ++Y G PF
Sbjct: 724 KLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPF 783
>Hs4506055 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 106 bits (264), Expect = 2e-22
Identities = 83/332 (25%), Positives = 146/332 (43%), Gaps = 58/332 (17%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGL 84
K +G GSF V G + A+K + + E IL+ + P +V L
Sbjct: 48 KTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKL 107
Query: 85 IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVL 144
+ +S+ Y++MEY G++ +++ H
Sbjct: 108 EFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF--------------------- 146
Query: 145 VVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILK 204
Y Q+ ++L S +L++RD+KP+NLL+ + G++ +
Sbjct: 147 ---YAAQIVLTFEYLHSLDLIYRDLKPENLLI-------------DQQGYI--------Q 182
Query: 205 IADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
+ DFGFA+ + + TLCG+P Y+APEI+ + YN D W++G ++YEM G PPF
Sbjct: 183 VTDFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM-----GFTDFFNNE 319
A +++++KI + ++ PS + L +L+R LL D R G D N++
Sbjct: 241 ADQPIQIYEKI--VSGKVRFPS--HFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHK 296
Query: 320 --VVTEDLTRYEQSYEPDLESKSKDVAESNMF 349
T+ + Y++ E K K +++ F
Sbjct: 297 WFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328
>7297080 [T] KOG0583 Serine/threonine protein kinase
Length = 329
Score = 106 bits (264), Expect = 2e-22
Identities = 89/291 (30%), Positives = 133/291 (45%), Gaps = 56/291 (19%)
Query: 4 ESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXX 63
++ DK + L + K IG G++A V G S G+ +A+K +S+
Sbjct: 51 KADDKSKPQKTILEEHGIILGKVIGTGNYAKVKIGFSEEYGKRVAVKIISKVKAPSEYTQ 110
Query: 64 XXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLI 123
EI +K + H +++ TS YLIM+ G L ++++RK L P
Sbjct: 111 KFLPREIEAVKGLHHENLITFYQSIETSHRVYLIMQLAENGTLLDYVRERK--FLDEPQS 168
Query: 124 KTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDY 183
+T+F+ QL SA++++ SK +VHRDIK +NL LLD
Sbjct: 169 RTLFK----------------------QLVSAVEYIHSKGVVHRDIKCENL-----LLDE 201
Query: 184 NDPKTFHELGFVGIYNLPILKIADFGFARFLPNTS-----LAETLCGSPLYMAPEILNYQ 238
N +N LK+ DFGFAR TS L++T CGS Y +PEIL
Sbjct: 202 N-------------WN---LKLIDFGFARKDTRTSDNQVILSKTFCGSYAYASPEILKGV 245
Query: 239 KYNA-KADLWSVGTVLYEMCCGRPPFKASN-HLELFQKIKKANDEITVPSN 287
Y+ +D+W+ G V Y M GR P+ SN H+ L K+ N + P +
Sbjct: 246 AYDPFMSDIWACGVVCYAMVFGRLPYDGSNVHILL----KRINQSLVFPKS 292
>Hs20547806 [R] KOG0589 Serine/threonine protein kinase
Length = 489
Score = 105 bits (263), Expect = 2e-22
Identities = 91/376 (24%), Positives = 158/376 (41%), Gaps = 56/376 (14%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
++Y V + IG+GSF + A+K + E +L K+KH
Sbjct: 2 DDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRK--EAVLLAKMKH 59
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV + Y++MEYC GDL IK++K + +I
Sbjct: 60 PNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMI--------------- 104
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+N+ Q+ + + K ++HRDIK +N+ L + G V
Sbjct: 105 -------LNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLT-------------QNGKV--- 141
Query: 199 NLPILKIADFGFARFLPNT-SLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
K+ DFG AR L N + A T G+P Y+ PEI YN K+D+WS+G +LYE+C
Sbjct: 142 -----KLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELC 196
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
+ PF+A++ L K+ + P + +L L++ + +P R T +
Sbjct: 197 TLKHPFQANSWKNLILKVCQG---CISPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLS 253
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTD----E 373
+V ++ P++ + + + S++ KQ+E + TD
Sbjct: 254 RGIVAR---LVQKCLPPEIIMEYGEEVLEEIKNSKHNTPRKKQEEEQDRKGSHTDLESIN 310
Query: 374 NTSVQTGVRRTSGKER 389
V++ +RR + +E+
Sbjct: 311 ENLVESALRRVNREEK 326
>CE17284 [T] KOG0583 Serine/threonine protein kinase
Length = 726
Score = 105 bits (263), Expect = 2e-22
Identities = 80/317 (25%), Positives = 134/317 (42%), Gaps = 66/317 (20%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y+V E+G G F V L + +AIK + + E+ L+ + H +
Sbjct: 11 YAVHDELGSGGFGKVRLATHLLTNQKVAIKIIDKKQLGHDLPRVQT--EMDALRNLSHQN 68
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I L T F+++MEYC+ G++ +I +++ L H
Sbjct: 69 ICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKERL--------------EESEARH--- 111
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ +QL SA+ F+ S+ HRD+KP+NLLL L
Sbjct: 112 -------FFRQLVSAIAFVHSQGYAHRDLKPENLLLTEDL-------------------- 144
Query: 201 PILKIADFGFARFLPNTSL----AETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYE 255
LK+ DFG + +T CGSP Y APE++ +Y +AD+WS+G +LY
Sbjct: 145 -HLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAYAAPELIQGLQYKGNEADVWSMGILLYT 203
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFN-----LIRGLLTFDPDSRM 310
+ G PF+ N +++KI+ S C+ EP+ + L+R +L P+ R+
Sbjct: 204 LLVGALPFEDDNMQIMYKKIQ---------SGCFYEPEFLSPLSKQLLRAMLQVVPERRI 254
Query: 311 GFTDFFNNEVVTEDLTR 327
++ + T+
Sbjct: 255 SVKKLLEHDWLNHKYTQ 271
>CE14798 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 422
Score = 105 bits (263), Expect = 2e-22
Identities = 81/294 (27%), Positives = 129/294 (43%), Gaps = 51/294 (17%)
Query: 27 IGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAIL-KKIKHPHIVGLI 85
IGKGSF VY+ + A+K +S+ E +L KHP +V L
Sbjct: 100 IGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAERNVLINNFKHPFLVSLH 159
Query: 86 DCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLV 145
+ Y ++++ G+L +++ K H+ +
Sbjct: 160 FSFQNKEKLYFVLDHLNGGELFSHLQREK--------------HFSESRSRF-------- 197
Query: 146 VNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKI 205
Y +++ AL +L KN+++RD+KP+NLLL D K + L +
Sbjct: 198 --YAAEIACALGYLHEKNIIYRDLKPENLLL--------DDKGY-------------LVL 234
Query: 206 ADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
DFG + + + T CG+P Y+APEI+ + Y+ D W +G+VLYEM G PPF
Sbjct: 235 TDFGLCKEDMQGSKTTSTFCGTPEYLAPEIILKKPYDKTVDWWCLGSVLYEMIFGLPPFY 294
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
+ +H E++ KI N + + N I LI GLL D R+G + F +
Sbjct: 295 SKDHNEMYDKI--INQPLRLKHN--ISVPCSELITGLLQKDRSKRLGHRNDFRD 344
>CE26793_1 [R] KOG0611 Predicted serine/threonine protein kinase
Length = 795
Score = 105 bits (263), Expect = 2e-22
Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 53/296 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
+ + K++G G++ V + R +A+K + +S EI I+ + HP+
Sbjct: 75 FEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIESKADLVRIRREIRIMSALNHPN 134
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
I+ + + L+MEY + G+L ++ + +L P E +
Sbjct: 135 IIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSL----------------PEAEARRI 178
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
R Q++SA+ + + HRD+K +N+ LLD N+
Sbjct: 179 FR--------QITSAVLYCHKHRVAHRDLKLENI-----LLDQNNN-------------- 211
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYEMCCG 259
KIADFG + + + +L T CGSPLY +PEI+N Y + D WS+G +LY + G
Sbjct: 212 --AKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKGPEVDCWSLGILLYTLVYG 269
Query: 260 RPPFKASNHLELFQKIKK-ANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
PF + + ++IK+ A E PS + LIR +L +P+ R D
Sbjct: 270 SMPFDGRDFNRMVRQIKRGAYFEPETPSTASM------LIRNMLRVNPERRATIFD 319
>CE15475 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 375
Score = 105 bits (262), Expect = 3e-22
Identities = 76/287 (26%), Positives = 131/287 (45%), Gaps = 51/287 (17%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGL 84
K +G GSF V + G A+K + + E IL+ I P +V +
Sbjct: 56 KTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNM 115
Query: 85 IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVL 144
+ +S+ Y+++E+ + G++ +++ H
Sbjct: 116 TFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRF--------------------- 154
Query: 145 VVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILK 204
Y Q+ A ++L S +L++RD+KP+NLL+ G+ LK
Sbjct: 155 ---YAAQIVLAFEYLHSLDLIYRDLKPENLLI-------------DSTGY--------LK 190
Query: 205 IADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
I DFGFA+ + + TLCG+P Y+APEI+ + YN D W++G ++YEM G PPF
Sbjct: 191 ITDFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 248
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
A +++++KI + ++ PS + +L +L++ LL D R G
Sbjct: 249 ADQPIQIYEKI--VSGKVKFPS--HFSNELKDLLKNLLQVDLTKRYG 291
>7304358 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 493
Score = 105 bits (262), Expect = 3e-22
Identities = 76/294 (25%), Positives = 127/294 (42%), Gaps = 44/294 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++NY +++E+GKG+F++V + + G A K ++ E I +K+
Sbjct: 11 SDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLER-EARICRKLH 69
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D + + YL+ + G+L I R E Y H
Sbjct: 70 HPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAR--------------EFYSEADASH 115
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ +VHRD+KP+NLLL +
Sbjct: 116 ----------CIQQILESVNHCHQNGVVHRDLKPENLLLASKAKG--------------- 150
Query: 198 YNLPILKIADFGFARFLPNTSLAET-LCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+K+ADFG A + A G+P Y++PE+L + Y D+W+ G +LY +
Sbjct: 151 ---AAVKLADFGLAIEVQGDHQAWFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYIL 207
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+ +IK + P + P+ NLI +LT +P+ R+
Sbjct: 208 LVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRI 261
>7290841 [D] KOG0591 NIMA (never in mitosis)-related G2-specific
serine/threonine protein kinase
Length = 735
Score = 105 bits (262), Expect = 3e-22
Identities = 87/331 (26%), Positives = 143/331 (42%), Gaps = 53/331 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
++Y V +G GSF YK G A K ++ EI++L++++H
Sbjct: 17 QDYEVLAVMGNGSFGTCYKVRDKSTGELFAWKGMNYDELDEAKCDALVS-EISVLRQLQH 75
Query: 79 PHIVGLID--CERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTE 136
P+IV R + Y++ME CA GDL +++ + ++
Sbjct: 76 PNIVQYYHHLVNREAKSVYIVMECCAGGDLAQIVQRAR--------------------SQ 115
Query: 137 HNGLNRVLVVNYLQQLSSALKFLRSK----NLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
+ L QL AL+ +K ++HRDIKP N+ L
Sbjct: 116 RQRFEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDA-------------- 161
Query: 193 GFVGIYNLPILKIADFGFARFL-PNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGT 251
K+ DFG AR L + S A + G+P YM+PE++ +KY+ K+D+W+VG
Sbjct: 162 -------AGNAKLGDFGLARMLRRDQSFAASFVGTPHYMSPELVKGRKYDRKSDVWAVGC 214
Query: 252 VLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
++YEMC RPPF+ +L +KI A E + Y L +I +L D + R G
Sbjct: 215 LVYEMCALRPPFRGRAFDQLSEKI--AQGEFSRIPAIY-STDLQEIIAFMLAVDHEQRPG 271
Query: 312 FTDFFNNEVVTEDLTRYEQSYEPDLESKSKD 342
+ +V +++ + + P L +D
Sbjct: 272 IEVIIRHPLVVRNISELDGKF-PILVDSGED 301
>Hs14735945 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 105 bits (261), Expect = 4e-22
Identities = 99/362 (27%), Positives = 153/362 (41%), Gaps = 62/362 (17%)
Query: 2 SSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXX 61
+S ++ K+ + + N+ K +GKGSF V G G AIKA+ +
Sbjct: 330 NSGTYGKIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDD 389
Query: 62 XXXXXXVEIAILK-KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
VE +L ++P + LI +T + +ME+ GDL + I+ + +
Sbjct: 390 DVECTMVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKG----RF 445
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
L + F Y ++ L+FL SK +++RD+K N+LL
Sbjct: 446 ELYRATF--------------------YAAEIMCGLQFLHSKGIIYRDLKLDNVLL---- 481
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQK 239
+ H +KIADFG + + S A T CG+P Y+APEIL K
Sbjct: 482 -----DRDGH------------IKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLK 524
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
Y D WS G +LYEM G+ PF + ELF+ I+ D P +I + +++
Sbjct: 525 YTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRV--DTPHYPR--WITKESKDILE 580
Query: 300 GLLTFDPDSRMGFT------DFFNNEVVTEDLTRYE-QSYEPDLESKSKDVAESNMFVSE 352
L +P R+G T FF T + T E + EP K K + + F E
Sbjct: 581 KLFEREPTKRLGVTGNIKIHPFFK----TINWTLLEKRRLEPPFRPKVKSPRDYSNFDQE 636
Query: 353 YL 354
+L
Sbjct: 637 FL 638
>Hs5453970 [T] KOG0694 Serine/threonine protein kinase
Length = 676
Score = 104 bits (260), Expect = 5e-22
Identities = 99/362 (27%), Positives = 153/362 (41%), Gaps = 62/362 (17%)
Query: 2 SSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXX 61
+S ++ K+ + + N+ K +GKGSF V G G AIKA+ +
Sbjct: 330 NSGTYGKIWEGSSKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYSAIKALKKDVVLIDD 389
Query: 62 XXXXXXVEIAILK-KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
VE +L ++P + LI +T + +ME+ GDL + I+ + +
Sbjct: 390 DVECTMVEKRVLTLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKG----RF 445
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
L + F Y ++ L+FL SK +++RD+K N+LL
Sbjct: 446 ELYRATF--------------------YAAEIMCGLQFLHSKGIIYRDLKLDNVLL---- 481
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQK 239
+ H +KIADFG + + S A T CG+P Y+APEIL K
Sbjct: 482 -----DRDGH------------IKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLK 524
Query: 240 YNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
Y D WS G +LYEM G+ PF + ELF+ I+ D P +I + +++
Sbjct: 525 YTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRV--DTPHYPR--WITKESKDILE 580
Query: 300 GLLTFDPDSRMGFT------DFFNNEVVTEDLTRYE-QSYEPDLESKSKDVAESNMFVSE 352
L +P R+G T FF T + T E + EP K K + + F E
Sbjct: 581 KLFEREPTKRLGMTGNIKIHPFFK----TINWTLLEKRRLEPPFRPKVKSPRDYSNFDQE 636
Query: 353 YL 354
+L
Sbjct: 637 FL 638
>Hs4505695 [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 556
Score = 104 bits (260), Expect = 5e-22
Identities = 77/296 (26%), Positives = 126/296 (42%), Gaps = 52/296 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E++ K +G+GSF+ V L R AIK + + E ++ ++ H
Sbjct: 80 EDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDH 139
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P V L + Y + Y G+L +I+K
Sbjct: 140 PFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKI------------------------G 175
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ Y ++ SAL++L K ++HRD+KP+N+LL + H
Sbjct: 176 SFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILL---------NEDMH-------- 218
Query: 199 NLPILKIADFGFARFLPNTSL---AETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYE 255
++I DFG A+ L S A + G+ Y++PE+L + +DLW++G ++Y+
Sbjct: 219 ----IQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQ 274
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
+ G PPF+A N +FQKI K E P + PK +L+ LL D R+G
Sbjct: 275 LVAGLPPFRAGNEYLIFQKIIKL--EYDFPEKFF--PKARDLVEKLLVLDATKRLG 326
>Hs20547878 [R] KOG0589 Serine/threonine protein kinase
Length = 758
Score = 104 bits (260), Expect = 5e-22
Identities = 85/319 (26%), Positives = 132/319 (40%), Gaps = 74/319 (23%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+ Y V K IG+G+F Y D ++ IK ++ KH
Sbjct: 2 DKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFE---------------------KH 40
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
I L + R +++MEYC GDL I +++ ++ I
Sbjct: 41 QMIPFLTENGR----LFIVMEYCDGGDLMKRINRQRGVLFSEDQI--------------- 81
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ + Q+S LK + + ++HRDIK QN+ L
Sbjct: 82 -------LGWFVQISLGLKHIHDRKILHRDIKAQNIFLSK-------------------- 114
Query: 199 NLPILKIADFGFARFLPNT-SLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
N + K+ DFG AR L N+ LA T G+P Y++PEI + YN K D+WS+G VLYE+C
Sbjct: 115 NGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELC 174
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
+ PF+ +N +L KI +A+ P + +L +LI L P R
Sbjct: 175 TLKHPFEGNNLQQLVLKICQAH---FAPISPGFSRELHSLISQLFQVSPRDRPSINSILK 231
Query: 318 NEVVTEDLTRY---EQSYE 333
+ + +Y E S+E
Sbjct: 232 RPFLENLIPKYLTPEVSFE 250
>Hs15619015 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 104 bits (260), Expect = 5e-22
Identities = 79/287 (27%), Positives = 130/287 (44%), Gaps = 51/287 (17%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGL 84
+ +G GSF V G + A+K +++ E IL+ I P +V L
Sbjct: 48 RTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKL 107
Query: 85 IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVL 144
+ +S YL+MEY G++ +++ H
Sbjct: 108 QFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACF--------------------- 146
Query: 145 VVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILK 204
Y Q+ A+++L S +L+HRD+KP+NLL+ + G+ L+
Sbjct: 147 ---YAAQVVLAVQYLHSLDLIHRDLKPENLLI-------------DQQGY--------LQ 182
Query: 205 IADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFK 264
+ DFGFA+ + + TLCG+P Y+APEI+ + YN D W++G ++YEM G PPF
Sbjct: 183 VTDFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY 240
Query: 265 ASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
A +++++KI + + PS + L +L+R LL D R G
Sbjct: 241 ADQPIQIYEKI--VSGRVRFPSK--LSSDLKHLLRSLLQVDLTKRFG 283
>At4g32830 [D] KOG0580 Serine/threonine protein kinase
Length = 294
Score = 104 bits (260), Expect = 5e-22
Identities = 77/296 (26%), Positives = 129/296 (43%), Gaps = 49/296 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R ++ + K +G+G F VY R +A+K + +S E+ I
Sbjct: 25 RWTLSDFDIGKPLGRGKFGHVYLAREKRSNHVVALKVLFKSQLQQSQVEHQLRREVEIQS 84
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
++HP+I+ L YLI+EY A G+L ++K K +
Sbjct: 85 HLRHPNILRLYGYFYDQKRVYLILEYAARGELYKDLQKCKYFSERR-------------- 130
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
Y+ L+ AL + K+++HRDIKP+NLL+ G
Sbjct: 131 ----------AATYVASLARALIYCHGKHVIHRDIKPENLLI----------------GA 164
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
G LKIADFG++ N T+CG+ Y+ PE++ +++A D+WS+G + Y
Sbjct: 165 QGE-----LKIADFGWSVHTFNRR--RTMCGTLDYLPPEMVESVEHDASVDIWSLGILCY 217
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
E G PPF+A H + +++I + ++ P I +LI +L + R+
Sbjct: 218 EFLYGVPPFEAMEHSDTYRRIVQV--DLKFPPKPIISASAKDLISQMLVKESSQRL 271
>SPBC32C12.03c [T] KOG0583 Serine/threonine protein kinase
Length = 423
Score = 104 bits (259), Expect = 6e-22
Identities = 82/291 (28%), Positives = 129/291 (44%), Gaps = 50/291 (17%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
N+ ++K IG GS V +++ G A+K + + E + + ++HP
Sbjct: 52 NWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQR-EALLGRLLRHP 110
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+I +IDC RT + Y++ EY G L +I R L
Sbjct: 111 NICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKL----------------------- 147
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
+ L ++ QL +AL +L +VHRD+K +N+LL D +
Sbjct: 148 -DEDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLT------QDSRQ----------- 189
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCC 258
+K+ DFG + F L T CGS + APE+L+ + Y + D+WS+G V+Y M C
Sbjct: 190 ---VKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVMVC 246
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
GR PF + L KIK + ++ PS YI +LI +L +P R
Sbjct: 247 GRVPFDDVSVPMLHSKIK--SGKLEFPS--YISEDCCSLIAAMLNVNPRKR 293
>Hs5031689 [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related
proteins
Length = 890
Score = 104 bits (259), Expect = 6e-22
Identities = 71/240 (29%), Positives = 111/240 (45%), Gaps = 42/240 (17%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVG 83
++ +G G F +VY G + GR++AIK + + E+AIL+ + HP IV
Sbjct: 579 DEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRN-EVAILQNLHHPGIVN 637
Query: 84 LIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRV 143
L T +++ME GD+ I S+E + L
Sbjct: 638 LECMFETPERVFVVMEKLH-GDMLEMIL----------------------SSEKSRLPER 674
Query: 144 LVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPIL 203
+ + Q+ AL+ L KN+VH D+KP+N+LL + +P P +
Sbjct: 675 ITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASA-----EP-------------FPQV 716
Query: 204 KIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPF 263
K+ DFGFAR + S ++ G+P Y+APE+L + YN D+WSVG ++Y G PF
Sbjct: 717 KLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPF 776
>Hs4505599 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 525
Score = 104 bits (259), Expect = 6e-22
Identities = 76/295 (25%), Positives = 129/295 (42%), Gaps = 52/295 (17%)
Query: 17 PTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKI 76
P + Y+ ++IG+G+ V+ + G+ +AIK ++ EI ++K++
Sbjct: 245 PKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIIN---EILVMKEL 301
Query: 77 KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTE 136
K+P+IV +D + +++MEY A G LT + TE
Sbjct: 302 KNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV------------------------TE 337
Query: 137 HNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVG 196
++ + ++ AL+FL + ++HRDIK N+LL G G
Sbjct: 338 TACMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLL----------------GMEG 381
Query: 197 IYNLPILKIADFGF-ARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYE 255
+K+ DFGF A+ P S T+ G+P +MAPE++ + Y K D+WS+G + E
Sbjct: 382 S-----VKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIE 436
Query: 256 MCCGRPPFKASNHLE-LFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
M G PP+ N L L+ E+ P + P + + L D + R
Sbjct: 437 MVEGEPPYLNENPLRALYLIATNGTPELQNPEK--LSPIFRDFLNRCLEMDVEKR 489
>ECU07g0360 [D] KOG0580 Serine/threonine protein kinase
Length = 272
Score = 104 bits (259), Expect = 6e-22
Identities = 80/306 (26%), Positives = 132/306 (42%), Gaps = 49/306 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+ + + + +G+G F V+ G +A+K + EI I +KH
Sbjct: 8 DRFEIGRLLGRGKFGQVWLAREREKGFIVALKIIPIKEIQTVETARQIRREIEIHSNLKH 67
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+I+ + + YLI+EY G+ F+ R +
Sbjct: 68 PNILRMYGHFHDKDNIYLILEYAGKGEFFKFLSDRGGKF----------------GEKET 111
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
L Y++Q+ AL +++ N++HRDIKP+NLLL G
Sbjct: 112 SL-------YIRQVMLALTYMKECNVIHRDIKPENLLL-------------------GSD 145
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
N LKIADFG+A + + T CG+ Y+APE++N +++ DLW +G + YE
Sbjct: 146 NQ--LKIADFGWAVYNADKRRM-TFCGTMEYLAPEMVNNDIHDSGIDLWCLGILTYEFLM 202
Query: 259 GRPPFKASNHLELFQKIKKAND-EITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G+ PF++ N + + KK N + T+P I + I LL P RM T+ N
Sbjct: 203 GKTPFESKNR-NMREAYKKINSLKYTIPET--ISSNASDFISRLLVLSPGDRMELTEALN 259
Query: 318 NEVVTE 323
+ + +
Sbjct: 260 HPFIVK 265
>ECU01g0630 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 488
Score = 104 bits (259), Expect = 6e-22
Identities = 78/292 (26%), Positives = 133/292 (44%), Gaps = 51/292 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y ++K +G+G++A Y + G A+K V EIAI K+ +P+
Sbjct: 40 YMLKKLLGRGAYAQCYLA-EIESGEQYAMKVVRLKDIKSRKVHEKLESEIAIHSKLDNPN 98
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V + R+S ++++E C G L +K+ L +H
Sbjct: 99 VVKMYRSFRSSEYVFMVLELCERGALDALLKRNGKLKERH-------------------- 138
Query: 141 NRVLVVNYLQQLSSALKFLR-SKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
V +++Q L +L S ++VHRD+K NL L D K +N
Sbjct: 139 ----VARFVKQTVEGLIYLHNSVSVVHRDLKLGNLFL--------DSK----------FN 176
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL--NYQKYNAKADLWSVGTVLYEMC 257
+ KI DFG + + + T+CG+P Y+APE+L ++ +AD+WS+G ++Y +
Sbjct: 177 V---KIGDFGLSAVIKDGEKKVTMCGTPNYIAPEVLFGKASGHSFEADIWSLGVIIYTLL 233
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
G PPF+ N ++++ IK N P NC + + +LI +L +P R
Sbjct: 234 VGVPPFQKKNVEDIYKMIKLNN--YIFPENCDLSSEAIDLITQILNTNPLER 283
>At2g25880 [D] KOG0580 Serine/threonine protein kinase
Length = 282
Score = 104 bits (259), Expect = 6e-22
Identities = 76/296 (25%), Positives = 129/296 (42%), Gaps = 49/296 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R T ++ + K +G+G F VY R +A+K + ++ E+ I
Sbjct: 13 RWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQS 72
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
++HP+I+ L YLI+EY G+L ++K K +
Sbjct: 73 HLRHPNILRLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERR-------------- 118
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
Y+ L+ AL + K+++HRDIKP+NLL+ G
Sbjct: 119 ----------AATYVASLARALIYCHGKHVIHRDIKPENLLI----------------GA 152
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
G LKIADFG++ N T+CG+ Y+ PE++ +++A D+WS+G + Y
Sbjct: 153 QGE-----LKIADFGWSVHTFNRR--RTMCGTLDYLPPEMVESVEHDASVDIWSLGILCY 205
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
E G PPF+A H E +++I + ++ P + +LI +L + R+
Sbjct: 206 EFLYGVPPFEAREHSETYKRIVQV--DLKFPPKPIVSSSAKDLISQMLVKESTQRL 259
>Hs4506067 [T] KOG0696 Serine/threonine protein kinase
Length = 672
Score = 103 bits (258), Expect = 8e-22
Identities = 85/301 (28%), Positives = 134/301 (44%), Gaps = 55/301 (18%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRN--IAIKAVSRSXXXXXXXXXXXXVEIAI 72
R+ +++ +GKGSF V L+ R G AIK + + VE +
Sbjct: 333 RVKLTDFNFLMVLGKGSFGKVM--LADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRV 390
Query: 73 LKKI-KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYP 131
L + K P + L C +T Y +MEY GDL + I++ V K + VF
Sbjct: 391 LALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQ----VGKFKEPQAVF---- 442
Query: 132 PPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
Y ++S L FL + +++RD+K N++L +
Sbjct: 443 ----------------YAAEISIGLFFLHKRGIIYRDLKLDNVMLDSE------------ 474
Query: 192 LGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVG 250
+KIADFG + + + T CG+P Y+APEI+ YQ Y D W+ G
Sbjct: 475 ---------GHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYG 525
Query: 251 TVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+LYEM G+PPF + ELFQ I + N ++ P + + + ++ +GL+T P R+
Sbjct: 526 VLLYEMLAGQPPFDGEDEDELFQSIMEHN--VSYPKS--LSKEAVSICKGLMTKHPAKRL 581
Query: 311 G 311
G
Sbjct: 582 G 582
>CE02586 [T] KOG0696 Serine/threonine protein kinase
Length = 861
Score = 103 bits (258), Expect = 8e-22
Identities = 100/387 (25%), Positives = 159/387 (40%), Gaps = 82/387 (21%)
Query: 2 SSESHDKVVAKAIRLP--TENYSVEKE--------IGKGSFAVVYKGLSLRDGRNIAIKA 51
SS+ D +A LP + N++V K +GKGSF V G AIK
Sbjct: 384 SSKPKDPAAPRASTLPLGSSNHNVIKASDFNFLTVLGKGSFGKVLLGEQKTTKELFAIKV 443
Query: 52 VSRSXXXXXXXXXXXXVEIAILKKIKHPH-IVGLIDCERTSSDFYLIMEYCALGDLTFFI 110
+ + E +L + P +V L C +T Y +ME+ GDL + I
Sbjct: 444 LKKDVIIQDDDVECTMTEKRVLALPEKPSFLVALHSCFQTMDRLYFVMEFVNGGDLMYQI 503
Query: 111 KKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIK 170
++ K P + V Y +++ L FL SK +++RD+K
Sbjct: 504 QQVGK--FKEP----------------------VAVFYAAEIAVGLFFLHSKGIIYRDLK 539
Query: 171 PQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLY 229
N++L + H +KI DFG + + + +T CG+P Y
Sbjct: 540 LDNVML---------ERDGH------------IKITDFGMCKENIFGDATTKTFCGTPDY 578
Query: 230 MAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCY 289
+APEI+ YQ Y D W+ G +L+EM G+PPF + ELF I + N ++ P +
Sbjct: 579 IAPEIILYQPYGKSVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHN--VSYPKS-- 634
Query: 290 IEPKLFNLIRGLLTFDPDSRMGFTDFFNNEVVTEDLTRYEQSYEPDLESKSKDVAESNMF 349
+ + +L + LL +P R+G T D ES S+D+ E F
Sbjct: 635 LSKEAVSLCKALLIKNPSKRLGCTG--------------------DDESASRDIKEHPFF 674
Query: 350 VS-EYLVKPLKQQESAHIPPTQTDENT 375
++ +Q + P +TD +T
Sbjct: 675 RRIDWFKIETRQIQPPFKPKLKTDRST 701
>At3g49370 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 103 bits (258), Expect = 8e-22
Identities = 82/299 (27%), Positives = 132/299 (43%), Gaps = 56/299 (18%)
Query: 21 YSVEKEIGKGSF-----AVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
Y + +E+G+G F A KG G+ +A+K +S+S E+ +LK
Sbjct: 142 YELGREVGRGHFGHTCWAKAKKGKI--KGQTVAVKIISKSKMTSALSIEDVRREVKLLKA 199
Query: 76 IK-HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+ H H+V D S + +++ME C G+L I R YP
Sbjct: 200 LSGHSHMVKFYDVFEDSDNVFVVMELCEGGELLDSILARGG-------------RYPEAE 246
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
+ R+LV Q+ SA F + +VHRD+KP+N L + D
Sbjct: 247 AK-----RILV-----QILSATAFFHLQGVVHRDLKPENFLFTSKNED------------ 284
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
+LK+ DFG + + + GS Y+APE+L ++ Y+ +AD+WS+G + Y
Sbjct: 285 ------AVLKVIDFGLSDYARFDQRLNDVVGSAYYVAPEVL-HRSYSTEADIWSIGVISY 337
Query: 255 EMCCGRPPFKASNHLELFQKIKKAN---DEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ CG PF +F+ + +AN D++ PS I P + ++ LL D RM
Sbjct: 338 ILLCGSRPFYGRTESAIFRCVLRANPNFDDLPWPS---ISPIAKDFVKRLLNKDHRKRM 393
>7297776 [D] KOG0580 Serine/threonine protein kinase
Length = 329
Score = 103 bits (258), Expect = 8e-22
Identities = 77/310 (24%), Positives = 132/310 (41%), Gaps = 48/310 (15%)
Query: 20 NYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHP 79
++ + +G+G F VY +A+K + + EI I ++KHP
Sbjct: 52 DFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHP 111
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
HI+ L+ S YL +E + G+L ++ N + P +
Sbjct: 112 HILRLLTWFHDESRIYLALEIASEGELFKHLRGAPN------------HRFDEPRS---- 155
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
Y Q+++AL + N++HRD+KP+N+LL +
Sbjct: 156 ------AKYTYQVANALNYCHLNNVIHRDLKPENILLTST-------------------- 189
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
LK+ADFG++ PN TLCG+ Y+ PE+++ Y+ D W +G + YE G
Sbjct: 190 -DDLKLADFGWSAHTPNNK-RRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVG 247
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PPF++++ + KI++ EI+ PS ++ LI GLL + R+ D +
Sbjct: 248 CPPFESNSTESTYSKIRRM--EISYPS--HLSKGCKELIGGLLRKESKGRITLVDVMTHY 303
Query: 320 VVTEDLTRYE 329
V + E
Sbjct: 304 WVKAGMAERE 313
>YDR490c [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 766
Score = 103 bits (257), Expect = 1e-21
Identities = 83/330 (25%), Positives = 142/330 (42%), Gaps = 68/330 (20%)
Query: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAIL 73
+++ +++ +++G GS++ V + G+ A+K +S+ VE L
Sbjct: 118 VKMGIKDFKFGEQLGDGSYSSVVLATARDSGKKYAVKVLSKEYLIRQKKVKYVTVEKLAL 177
Query: 74 KKIKHPH-IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+K+ I L + + Y ++EY GD IKK
Sbjct: 178 QKLNGTKGIFKLFFTFQDEASLYFLLEYAPHGDFLGLIKK-------------------- 217
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
+ LN Y Q+ A+ L + ++HRDIKP+N+LL D N
Sbjct: 218 ----YGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILL-----DKNMK------ 262
Query: 193 GFVGIYNLPILKIADFGFARFLP----NTS----------LAETLCGSPLYMAPEILNYQ 238
+K+ DFG A+ LP NT+ +++ G+ Y++PE+LN
Sbjct: 263 ----------VKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDN 312
Query: 239 KYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLI 298
+++ D+W+ G +LY+M G+PPFKA+N FQK+ K T ++ +L+
Sbjct: 313 YTDSRCDIWAFGCILYQMLAGKPPFKAANEYLTFQKVMKIQYAFTAGFPQIVK----DLV 368
Query: 299 RGLLTFDPDSRMGF----TDFFNNEVVTED 324
+ LL DP+ R+ F +EV ED
Sbjct: 369 KKLLVRDPNDRLTIKQIKAHLFFHEVNFED 398
>Hs20127418 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 664
Score = 103 bits (257), Expect = 1e-21
Identities = 79/294 (26%), Positives = 125/294 (41%), Gaps = 44/294 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
T+ Y + ++IGKG+F+VV + + L G A K ++ E I + +K
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER-EARICRLLK 69
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
H +IV L D YL+ + G+L I R E+Y H
Sbjct: 70 HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAR--------------EYYSEADASH 115
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ A+ +VHRD+KP+NLLL +
Sbjct: 116 ----------CIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKG--------------- 150
Query: 198 YNLPILKIADFGFARFLPNTSLAET-LCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+K+ADFG A + A G+P Y++PE+L + Y D+W+ G +LY +
Sbjct: 151 ---AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYIL 207
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + +L+Q+IK + P + P+ NLI +LT +P R+
Sbjct: 208 LVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRI 261
>7295426 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 490
Score = 103 bits (257), Expect = 1e-21
Identities = 83/303 (27%), Positives = 138/303 (45%), Gaps = 54/303 (17%)
Query: 14 IRLPTENYSVEKEIGKGSFAVVY---KGLSLRDGRNIAIKAVSR-SXXXXXXXXXXXXVE 69
I+L +++ ++K +GKG + V+ K + A+K + + S E
Sbjct: 70 IKLGPKDFELKKVLGKGGYGKVFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAE 129
Query: 70 IAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEH 129
IL+ +KHP IV L+ +T YLI+EY + G+L F +R+ + L+ T F
Sbjct: 130 RNILEAVKHPFIVELVYAFQTDGKLYLILEYLSGGEL-FMHLEREGIFLEDT---TCF-- 183
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTF 189
YL ++ AL L +++RD+KP+N+LL
Sbjct: 184 ------------------YLSEIILALGHLHKLGIIYRDLKPENILLDAQ---------- 215
Query: 190 HELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWS 248
G V K+ DFG + + + T CG+ YMAPEIL + D WS
Sbjct: 216 ---GHV--------KLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTRSGHGKAVDWWS 264
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G ++++M G PPF A N + + I KA ++ +P+ Y+ P+ +L+R L+
Sbjct: 265 LGALMFDMLTGVPPFTAENRKKTIETILKA--KLNLPA--YLTPEARDLVRRLMKRQEPQ 320
Query: 309 RMG 311
R+G
Sbjct: 321 RLG 323
>Hs14141724 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 499
Score = 103 bits (256), Expect = 1e-21
Identities = 77/294 (26%), Positives = 125/294 (42%), Gaps = 44/294 (14%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
T+ Y + +E+GKG+F+VV + + + G+ A K ++ E I + +K
Sbjct: 11 TDEYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKLER-EARICRLLK 69
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+IV L D YL+ + G+L I R E+Y H
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAR--------------EYYSEADASH 115
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+QQ+ ++ +VHRD+KP+NLLL +
Sbjct: 116 ----------CIQQILESVNHCHLNGIVHRDLKPENLLLASKSKG--------------- 150
Query: 198 YNLPILKIADFGFARFLPNTSLAET-LCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
+K+ADFG A + A G+P Y++PE+L Y D+W+ G +LY +
Sbjct: 151 ---AAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYIL 207
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
G PPF + L+Q+IK + P + P+ +LI +LT +P R+
Sbjct: 208 LVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRI 261
>At1g48490 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1244
Score = 103 bits (256), Expect = 1e-21
Identities = 108/396 (27%), Positives = 167/396 (41%), Gaps = 55/396 (13%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R+ +++ V K I +G+F V G AIK + ++ E IL
Sbjct: 822 RISIDDFEVMKSISRGAFGHVILARKNTTGDLFAIKVLRKADMIRKNAVESILAERDILI 881
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
++P +V S + YL+MEY GD ++K L
Sbjct: 882 NARNPFVVRFFYSFTCSENLYLVMEYLNGGDFYSMLRKIGCL------------------ 923
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
E N RV Y+ ++ AL++L S+ +VHRD+KP NLL+ D + T L
Sbjct: 924 DEANA--RV----YIAEVVLALEYLHSEGVVHRDLKPDNLLIAH---DGHVKLTDFGLSK 974
Query: 195 VGIYNL------PILKIADFGFARF--LPNTSLAETLCGSPLYMAPEILNYQKYNAKADL 246
VG+ N P+ LP + G+P Y+APEIL + A AD
Sbjct: 975 VGLINNTDDLSGPVSSATSLLVEEKPKLPTLDHKRSAVGTPDYLAPEILLGTGHGATADW 1034
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDE-ITVPSNCYIEPKLFNLIRGLLTFD 305
WSVG +LYE G PPF A + ++F I N + VP + E + +LI LLT D
Sbjct: 1035 WSVGIILYEFLVGIPPFNADHPQQIFDNILNRNIQWPPVPEDMSHEAR--DLIDRLLTED 1092
Query: 306 PDSRMGF-------TDFFNNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPL 358
P R+G F ++ L + + ++ PD S++ +++ F S Y
Sbjct: 1093 PHQRLGARGAAEVKQHSFFKDIDWNTLAQQKAAFVPD----SENAFDTSYFQSRY----S 1144
Query: 359 KQQESAHIPPTQTDENTSVQTGVRRTSGKERLATNH 394
PT +E++S + +SG RL+ +H
Sbjct: 1145 WNYSGERCFPTNENEDSSEGDSLCGSSG--RLSNHH 1178
>Hs4506057 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 351
Score = 102 bits (255), Expect = 2e-21
Identities = 75/293 (25%), Positives = 131/293 (44%), Gaps = 51/293 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E++ +K +G GSF V + A+K + + E IL+ +
Sbjct: 42 EDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF 101
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P +V L + +S+ Y++MEY G++ +++ H
Sbjct: 102 PFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARF--------------- 146
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
Y Q+ ++L S +L++RD+KP+NLL+ G++
Sbjct: 147 ---------YAAQIVLTFEYLHSLDLIYRDLKPENLLI-------------DHQGYI--- 181
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
++ DFGFA+ + + TLCG+P Y+APEI+ + YN D W++G ++YEM
Sbjct: 182 -----QVTDFGFAKRVKGRTW--TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 234
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
G PPF A +++++KI + ++ PS + L +L+R LL D R G
Sbjct: 235 GYPPFFADQPIQIYEKI--VSGKVRFPS--HFSSDLKDLLRNLLQVDLTKRFG 283
>Hs16507245 [T] KOG0583 Serine/threonine protein kinase
Length = 358
Score = 102 bits (254), Expect = 2e-21
Identities = 90/310 (29%), Positives = 136/310 (43%), Gaps = 54/310 (17%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
L + Y V +GKGS+A V S R N+A+K + R E+ IL
Sbjct: 7 LRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILAT 66
Query: 76 IKHPHIVGLIDCERTSSD-FYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+ H I+ + TS Y+IME GDL FIK + L
Sbjct: 67 VNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGAL------------------ 108
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
H + R + +QLSSA+K+ ++VHRD+K +NLLL D+N
Sbjct: 109 --HEDVARKM----FRQLSSAVKYCHDLDIVHRDLKCENLLLDK---DFN---------- 149
Query: 195 VGIYNLPILKIADFGFARFLPNTS-----LAETLCGSPLYMAPEILNYQKYNAKA-DLWS 248
+K++DFGF++ S L++T CGS Y APE+L Y K D+WS
Sbjct: 150 --------IKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWS 201
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G +LY M CG P+ S+ ++ + K+ + N E K +LI +L D
Sbjct: 202 LGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECK--DLIYRMLQPDVSQ 259
Query: 309 RMGFTDFFNN 318
R+ + ++
Sbjct: 260 RLHIDEILSH 269
>CE21615 [T] KOG0578 p21-activated serine/threonine protein kinase
Length = 378
Score = 102 bits (254), Expect = 2e-21
Identities = 80/303 (26%), Positives = 130/303 (42%), Gaps = 59/303 (19%)
Query: 17 PTENYSVEKEIGKGSFAVVYKGLSLRDGRNIA----IKAVSRSXXXXXXXXXXXXVEIAI 72
P Y ++K+IG G+ V+ N+A + AV R EI +
Sbjct: 104 PLGKYEMKKQIGVGASGTVFVA-------NVAGSTDVVAVKRMAFKTQPKKEMLLTEIKV 156
Query: 73 LKKIKHPHIVGLIDCERTSSD-FYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYP 131
+K+ +HP++V I+ +D +++M+Y G+LT + K +
Sbjct: 157 MKQYRHPNLVNYIESYLVDADDLWVVMDYLEGGNLTDVVVKTE----------------- 199
Query: 132 PPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
L+ + LQ+ AL FL ++VHRDIK N+LL
Sbjct: 200 --------LDEGQIAAVLQECLKALHFLHRHSIVHRDIKSDNVLL--------------- 236
Query: 192 LGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGT 251
G G +K+ D GF + S +T+ G+P +M+PEILN ++YN K D+WS+G
Sbjct: 237 -GMNGE-----VKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGI 290
Query: 252 VLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
+ EM G PP+ L+ I + N + + + + N + L DPD R
Sbjct: 291 MALEMIDGEPPYLRETPLKAIYLIAQ-NGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRAD 349
Query: 312 FTD 314
T+
Sbjct: 350 TTE 352
>YLR248w [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 610
Score = 102 bits (253), Expect = 3e-21
Identities = 88/340 (25%), Positives = 144/340 (41%), Gaps = 69/340 (20%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRN---------IAIKAVSRSXXXX------------ 59
Y + +IG+G+F+ V++ + ++ N +AIK + ++
Sbjct: 163 YKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGK 222
Query: 60 ----XXXXXXXXVEIAILKKIKH--PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKR 113
E+A+ K + IV ID + T S +Y+I E G++ I +
Sbjct: 223 DSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVR- 281
Query: 114 KNLVLKHPLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQN 173
++ + H ++QL+ A+K + S +VHRDIKP+N
Sbjct: 282 -------------LTYFSEDLSRH----------VIKQLALAVKHMHSLGVVHRDIKPEN 318
Query: 174 LL---------LCTPLLDYNDPKTFHELGF----VGIYNLPILKIADFGFAR--FLPNTS 218
LL + L +DP+T + G VG + I+K+ADFG ++ F NT
Sbjct: 319 LLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNT- 377
Query: 219 LAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKA 278
+T CG+ Y APE++ + Y+ K D+W +G VLY M CG PPF L +KI +
Sbjct: 378 --KTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRG 435
Query: 279 NDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
P I N + LL +P R F ++
Sbjct: 436 EYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDD 475
>YLR096w [T] KOG0583 Serine/threonine protein kinase
Length = 1147
Score = 102 bits (253), Expect = 3e-21
Identities = 97/424 (22%), Positives = 172/424 (39%), Gaps = 77/424 (18%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
T+ V K + + S A ++K SL +N + + V A L +I
Sbjct: 121 TKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQIL 180
Query: 78 -HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTE 136
HPHI L + S+ FY++ EY + G L +I +
Sbjct: 181 YHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYI------------------------IQ 216
Query: 137 HNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVG 196
H L + + ++SAL++L + N+VHRD+K +N+++ +
Sbjct: 217 HGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSS----------------- 259
Query: 197 IYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNA-KADLWSVGTVLYE 255
+KI DFG + T CGS + APE+L Q Y + D+WS G VLY
Sbjct: 260 ----GEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYV 315
Query: 256 MCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDF 315
+ CG+ PF N L +KIKK ++ PS+ IE + +L+ ++ DP R +
Sbjct: 316 LVCGKVPFDDENSSILHEKIKKG--KVDYPSHLSIE--VISLLTRMIVVDPLRRATLKNV 371
Query: 316 FNNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEY--------------LVKPLKQQ 361
+ + SY P+ + ++ +S + Y L++ + ++
Sbjct: 372 VEHPWMNRGYDFKAPSYVPNRVPLTPEMIDSQVLKEMYRLEFIDDIEDTRRSLIRLVTEK 431
Query: 362 ESAHIPPTQTDE-------NTSVQTGVRRTSGKERLATNH---PPHQQIH--PEDNSQNP 409
E + D+ ++S+ ++ ++ L NH P Q + P+ N ++P
Sbjct: 432 EYIQLSQEYWDKLSNAKGLSSSLNNNYLNSTAQQTLIQNHITSNPSQSGYNEPDSNFEDP 491
Query: 410 EQSY 413
+Y
Sbjct: 492 TLAY 495
>Hs4759050 [T] KOG0603 Ribosomal protein S6 kinase
Length = 740
Score = 102 bits (253), Expect = 3e-21
Identities = 80/294 (27%), Positives = 135/294 (45%), Gaps = 52/294 (17%)
Query: 21 YSVEKEIGKGSFAVVY--KGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
+ + K +G+GSF V+ K +S D R + V + +E IL ++ H
Sbjct: 68 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNH 127
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P IV L +T YLI+++ GDL F + K ++ +K
Sbjct: 128 PFIVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKF------------- 172
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
YL +L+ AL L S +++RD+KP+N+LL E G +
Sbjct: 173 ---------YLAELALALDHLHSLGIIYRDLKPENILL-------------DEEGHI--- 207
Query: 199 NLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
K+ DFG ++ + + A + CG+ YMAPE++N + + AD WS G +++EM
Sbjct: 208 -----KLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEML 262
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
G PF+ + E I KA ++ +P ++ P+ +L+R L +P +R+G
Sbjct: 263 TGTLPFQGKDRKETMTMILKA--KLGMPQ--FLSPEAQSLLRMLFKRNPANRLG 312
Score = 81.6 bits (200), Expect = 4e-15
Identities = 68/247 (27%), Positives = 112/247 (44%), Gaps = 48/247 (19%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
T+ Y V+++IG GS++V + + A+K + +S +EI +L+ +
Sbjct: 419 TDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEE-----IEI-LLRYGQ 472
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
HP+I+ L D Y++ E G+L I ++K
Sbjct: 473 HPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF-------------------SE 513
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+ VL ++ +++L ++ +VHRD+KP N+L Y D E G
Sbjct: 514 REASAVLFT-----ITKTVEYLHAQGVVHRDLKPSNIL-------YVD-----ESG---- 552
Query: 198 YNLPILKIADFGFARFL-PNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
N ++I DFGFA+ L L T C + ++APE+L Q Y+A D+WS+G +LY M
Sbjct: 553 -NPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTM 611
Query: 257 CCGRPPF 263
G PF
Sbjct: 612 LTGYTPF 618
>At5g62310 [TR] KOG0606 Microtubule-associated serine/threonine kinase and
related proteins
Length = 1168
Score = 102 bits (253), Expect = 3e-21
Identities = 99/375 (26%), Positives = 162/375 (42%), Gaps = 62/375 (16%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILK 74
R E++ + K I +G+F V+ G AIK + ++ E IL
Sbjct: 748 RTSIEDFEIIKPISRGAFGRVFLAKKRATGDLFAIKVLKKADMIRKNAVESILAERNILI 807
Query: 75 KIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+++P +V + YL+MEY GDL + +NL
Sbjct: 808 SVRNPFVVRFFYSFTCRENLYLVMEYLNGGDLFSLL---RNL------------------ 846
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
L+ + Y+ ++ AL++L S N++HRD+KP NLL+ D + T L
Sbjct: 847 ---GCLDEDMARIYIAEVVLALEYLHSVNIIHRDLKPDNLLINQ---DGHIKLTDFGLSK 900
Query: 195 VGIYNLP-----ILKIADFGFARFLPNTSLAE-----------TLCGSPLYMAPEILNYQ 238
VG+ N + + GF F + S A+ + G+P Y+APEIL
Sbjct: 901 VGLINSTDDLSGESSLGNSGF--FAEDGSKAQHSQGKDSRKKHAVVGTPDYLAPEILLGM 958
Query: 239 KYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPS-NCYIEPKLFNL 297
+ AD WSVG +L+E+ G PPF A ++F+ I N +I P+ I + +L
Sbjct: 959 GHGKTADWWSVGVILFEVLVGIPPFNAETPQQIFENI--INRDIPWPNVPEEISYEAHDL 1016
Query: 298 IRGLLTFDPDSRMGFT-------DFFNNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFV 350
I LLT +P R+G T F ++ + L R + + P E + +++ F+
Sbjct: 1017 INKLLTENPVQRLGATGAGEVKQHHFFKDINWDTLARQKAMFVPSAEPQ-----DTSYFM 1071
Query: 351 SEYLVKPLKQQESAH 365
S Y+ P + E+ H
Sbjct: 1072 SRYIWNP--EDENVH 1084
>7302861 [T] KOG0696 Serine/threonine protein kinase
Length = 700
Score = 102 bits (253), Expect = 3e-21
Identities = 81/349 (23%), Positives = 149/349 (42%), Gaps = 54/349 (15%)
Query: 10 VAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVE 69
++K + +++ K IGKGSF V A+K + + E
Sbjct: 360 MSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNE 419
Query: 70 IAILKKI-KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFE 128
IL + P +V + C +T + +MEYC GDL + ++
Sbjct: 420 KKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQ----------------- 462
Query: 129 HYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKT 188
++ + + Y +++ AL FL +++++RD+K N+LL
Sbjct: 463 -------QYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGE--------- 506
Query: 189 FHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLW 247
G V K+ DFG ++ + T CG+P YMAPEI++Y Y+ AD W
Sbjct: 507 ----GHV--------KLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWW 554
Query: 248 SVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPD 307
S G +L+E G+ PF+ + +F+ IK + + P + +E ++I LT P+
Sbjct: 555 SFGVLLFEFMAGQAPFEGDDETTVFRNIK--DKKAVFPKHFSVE--AMDIITSFLTKKPN 610
Query: 308 SRMGFTDFFNNEVVTEDLTR---YEQSYEPDLESKSKDVAESNMFVSEY 353
+R+G + E+ T R ++++ ++E K + + +S +
Sbjct: 611 NRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNF 659
>Hs4502567_1 [T] KOG0033 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 360
Score = 102 bits (253), Expect = 3e-21
Identities = 76/306 (24%), Positives = 133/306 (42%), Gaps = 42/306 (13%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV--EIAILKKIKH 78
Y + + IGKG F+VV + ++ G+ A+K V + + E +I +KH
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKH 71
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
PHIV L++ + Y++ E+ DL F I KR + +
Sbjct: 72 PHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVY------------------ 113
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
+ + +Y++Q+ AL++ N++HRD+KP +LL +
Sbjct: 114 --SEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASK------------------E 153
Query: 199 NLPILKIADFGFARFLPNTSL-AETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
N +K+ FG A L + L A G+P +MAPE++ + Y D+W G +L+ +
Sbjct: 154 NSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILL 213
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G PF + LF+ I K ++ +I +L+R +L DP R+ + N
Sbjct: 214 SGCLPFYGTKE-RLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALN 272
Query: 318 NEVVTE 323
+ + E
Sbjct: 273 HPWLKE 278
>Hs22068916 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 101 bits (252), Expect = 4e-21
Identities = 83/301 (27%), Positives = 132/301 (43%), Gaps = 55/301 (18%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRN--IAIKAVSRSXXXXXXXXXXXXVEIAI 72
R+ +++ +GKGSF V LS R G + A+K + + VE +
Sbjct: 336 RMKLTDFNFLMVLGKGSFGKVM--LSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRV 393
Query: 73 LKKI-KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYP 131
L K P + L C +T Y +MEY GDL + I++ H
Sbjct: 394 LALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPH----------- 442
Query: 132 PPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
V Y +++ L FL+SK +++RD+K N++L +
Sbjct: 443 -------------AVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE------------ 477
Query: 192 LGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVG 250
+KIADFG + + + +T CG+P Y+APEI+ YQ Y D W+ G
Sbjct: 478 ---------GHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFG 528
Query: 251 TVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+LYEM G+ PF+ + ELFQ I + N + P + + + + +GL+T P R+
Sbjct: 529 VLLYEMLAGQAPFEGEDEDELFQSIMEHN--VAYPKS--MSKEAVAICKGLMTKHPGKRL 584
Query: 311 G 311
G
Sbjct: 585 G 585
>Hs20127450 [T] KOG0696 Serine/threonine protein kinase
Length = 673
Score = 101 bits (252), Expect = 4e-21
Identities = 83/301 (27%), Positives = 132/301 (43%), Gaps = 55/301 (18%)
Query: 15 RLPTENYSVEKEIGKGSFAVVYKGLSLRDGRN--IAIKAVSRSXXXXXXXXXXXXVEIAI 72
R+ +++ +GKGSF V LS R G + A+K + + VE +
Sbjct: 336 RMKLTDFNFLMVLGKGSFGKVM--LSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRV 393
Query: 73 LKKI-KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYP 131
L K P + L C +T Y +MEY GDL + I++ H
Sbjct: 394 LALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPH----------- 442
Query: 132 PPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHE 191
V Y +++ L FL+SK +++RD+K N++L +
Sbjct: 443 -------------AVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE------------ 477
Query: 192 LGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVG 250
+KIADFG + + + +T CG+P Y+APEI+ YQ Y D W+ G
Sbjct: 478 ---------GHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFG 528
Query: 251 TVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+LYEM G+ PF+ + ELFQ I + N + P + + + + +GL+T P R+
Sbjct: 529 VLLYEMLAGQAPFEGEDEDELFQSIMEHN--VAYPKS--MSKEAVAICKGLMTKHPGKRL 584
Query: 311 G 311
G
Sbjct: 585 G 585
>Hs14589904 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 400
Score = 101 bits (252), Expect = 4e-21
Identities = 55/174 (31%), Positives = 92/174 (52%), Gaps = 22/174 (12%)
Query: 149 LQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKIADF 208
++ + A+++L S N+ HRD+KP+NLL + + ILK+ DF
Sbjct: 167 MKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPN------------------AILKLTDF 208
Query: 209 GFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNH 268
GFA+ + + T C +P Y+APE+L +KY+ D+WS+G ++Y + CG PPF +++
Sbjct: 209 GFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHG 268
Query: 269 LELF----QKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
L + +I+ E P + ++ LIR LL +P RM T+F N+
Sbjct: 269 LAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
>Hs10863901 [T] KOG0604 MAP kinase-activated protein kinase 2
Length = 370
Score = 101 bits (252), Expect = 4e-21
Identities = 55/174 (31%), Positives = 92/174 (52%), Gaps = 22/174 (12%)
Query: 149 LQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILKIADF 208
++ + A+++L S N+ HRD+KP+NLL + + ILK+ DF
Sbjct: 167 MKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPN------------------AILKLTDF 208
Query: 209 GFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNH 268
GFA+ + + T C +P Y+APE+L +KY+ D+WS+G ++Y + CG PPF +++
Sbjct: 209 GFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHG 268
Query: 269 LELF----QKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
L + +I+ E P + ++ LIR LL +P RM T+F N+
Sbjct: 269 LAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
>CE26649 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 648
Score = 101 bits (252), Expect = 4e-21
Identities = 78/289 (26%), Positives = 130/289 (43%), Gaps = 49/289 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + +GKG FA Y+ + +A K V +S E+ I +++ H +
Sbjct: 38 YEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKMTQEVQIHRELGHIN 97
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV L + + + Y+ +E CA R++L+ H K V E P +
Sbjct: 98 IVKLFNFFEDNLNVYITLELCA----------RRSLMELHKRRKAVTE----PEARY--- 140
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Q+ + +L N++HRD+K NL L L
Sbjct: 141 -------FTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDL-------------------- 173
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGR 260
++KI DFG A + +TLCG+P Y+APE+LN ++ + D+W+VG +LY + G+
Sbjct: 174 -VVKIGDFGLATTVNGDERKKTLCGTPNYIAPEVLNKAGHSFEVDIWAVGCILYILLFGQ 232
Query: 261 PPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
PPF++ + E + +I+ N T+PS +LIR +L +P R
Sbjct: 233 PPFESKSLEETYSRIRHNN--YTIPS--IATQPAASLIRKMLDPEPTRR 277
>At5g24430 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 594
Score = 101 bits (252), Expect = 4e-21
Identities = 81/299 (27%), Positives = 132/299 (44%), Gaps = 56/299 (18%)
Query: 21 YSVEKEIGKGSF-----AVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
Y + KE+G+G F A KG + +A+K +S++ E+ +LK
Sbjct: 143 YELGKEVGRGHFGHTCWAKAKKGKM--KNQTVAVKIISKAKMTSTLSIEDVRREVKLLKA 200
Query: 76 IK-HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+ H H+V D + + +++ME C G+L I R YP
Sbjct: 201 LSGHRHMVKFYDVYEDADNVFVVMELCEGGELLDRILARGG-------------RYPEVD 247
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
+ R+LV Q+ SA F + +VHRD+KP+N L + D
Sbjct: 248 AK-----RILV-----QILSATAFFHLQGVVHRDLKPENFLFTSRNED------------ 285
Query: 195 VGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
ILK+ DFG + F+ + GS Y+APE+L ++ Y+ +AD+WS+G + Y
Sbjct: 286 ------AILKVIDFGLSDFIRYDQRLNDVVGSAYYVAPEVL-HRSYSTEADMWSIGVISY 338
Query: 255 EMCCGRPPFKASNHLELFQKIKKAN---DEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ CG PF +F+ + +AN +++ PS I P + ++ LL D RM
Sbjct: 339 ILLCGSRPFYGRTESAIFRCVLRANPNFEDMPWPS---ISPTAKDFVKRLLNKDHRKRM 394
>Hs20070247_2 [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 378
Score = 101 bits (252), Expect = 4e-21
Identities = 78/302 (25%), Positives = 136/302 (44%), Gaps = 52/302 (17%)
Query: 17 PTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEI-AILKK 75
PT+ + K IGKGSF V DG+ A+K + + E +LK
Sbjct: 41 PTD-FDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQKKIVLNRKEQKHIMAERNVLLKN 99
Query: 76 IKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPST 135
+KHP +VGL +T+ Y ++++ G+L F +++ ++
Sbjct: 100 VKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSF------------------P 141
Query: 136 EHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFV 195
EH Y +++SAL +L S +V+RD+KP+N+L+ +G V
Sbjct: 142 EHRAR------FYAAEIASALGYLHSIKIVYRDLKPENILV-------------DSVGHV 182
Query: 196 GIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
+ DFG + + + T CG+P Y+APE++ Q Y+ D W +G VLY
Sbjct: 183 --------VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLY 234
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTD 314
EM G PPF + E++ I + +++ + + ++++ LL D +R+G +
Sbjct: 235 EMLYGLPPFYCRDVAEMYDNI--LHKPLSLRPG--VSLRAWSILEELLEKDRQNRLGAKE 290
Query: 315 FF 316
F
Sbjct: 291 DF 292
>YKL101w [D] KOG0588 Serine/threonine protein kinase
Length = 1518
Score = 101 bits (251), Expect = 5e-21
Identities = 75/255 (29%), Positives = 121/255 (47%), Gaps = 51/255 (20%)
Query: 69 EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFE 128
EI I+K I H +++ L + S+ YL++EY G+L ++ + L
Sbjct: 164 EIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKL------------ 211
Query: 129 HYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKT 188
P E ++Y +Q+ + + S N+ HRD+KP+NLLL D K
Sbjct: 212 ----PERE--------AIHYFKQIVEGVSYCHSFNICHRDLKPENLLL--------DKKN 251
Query: 189 FHELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYN-AKADL 246
+KIADFG A LPN L +T CGSP Y +PEI+ + Y+ +D+
Sbjct: 252 RR------------IKIADFGMAALELPN-KLLKTSCGSPHYASPEIVMGRPYHGGPSDV 298
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
WS G VL+ + G PF N +L K++ + + +PSN E + +LI +L DP
Sbjct: 299 WSCGIVLFALLTGHLPFNDDNIKKLLLKVQ--SGKYQMPSNLSSEAR--DLISKILVIDP 354
Query: 307 DSRMGFTDFFNNEVV 321
+ R+ + + ++
Sbjct: 355 EKRITTQEILKHPLI 369
>Hs22050308_2 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 291
Score = 101 bits (251), Expect = 5e-21
Identities = 80/298 (26%), Positives = 129/298 (42%), Gaps = 59/298 (19%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVS---RSXXXXXXXXXXXXVEIAILKKIKHPHI 81
++IG G+F+ Y+ + G +A+K V+ + EI ++ + HP+I
Sbjct: 24 QQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNI 83
Query: 82 VGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLN 141
+ ++ S++ L +E+ A G + + K +
Sbjct: 84 IRMLGATCEKSNYNLFIEWMAGGSVAHLLSK------------------------YGAFK 119
Query: 142 RVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLP 201
+V+NY +QL L +L ++HRD+K NLL+ D +
Sbjct: 120 ESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLI-----DSTGQR-------------- 160
Query: 202 ILKIADFGFARFLPN--TSLAE---TLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
L+IADFG A L + T E L G+ +MAPE+L Q+Y D+WSVG + EM
Sbjct: 161 -LRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEM 219
Query: 257 CCGRPPFKA---SNHLELFQK--IKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
C +PP+ A SNHL L K I A ++PS ++ P L ++ L P R
Sbjct: 220 ACAKPPWNAEKHSNHLALIFKVIIASATTAPSIPS--HLSPGLRDVALRCLELQPQDR 275
>At3g17510 [T] KOG0583 Serine/threonine protein kinase
Length = 446
Score = 100 bits (250), Expect = 7e-21
Identities = 86/311 (27%), Positives = 134/311 (42%), Gaps = 55/311 (17%)
Query: 4 ESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXX 63
+ +K K +RL Y + + +G+G+F V G + A+K + +S
Sbjct: 5 QEEEKKAEKGMRLG--KYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFS 62
Query: 64 XXXXVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLI 123
EI LK +KHPHIV L + + + ++ME G+L I L
Sbjct: 63 LQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKL------- 115
Query: 124 KTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDY 183
TE +G QQL + + SK + HRD+K +N+LL
Sbjct: 116 -----------TETDGR------KMFQQLIDGISYCHSKGVFHRDLKLENVLL------- 151
Query: 184 NDPKTFHELGFVGIYNLPILKIADFGFA---RFLPNTSLAETLCGSPLYMAPEILNYQKY 240
D K +KI DFG + + + L T CGSP Y+APE+L + Y
Sbjct: 152 -DAKGH-------------IKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGY 197
Query: 241 N-AKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIR 299
+ A +D+WS G +LY + G PF N L+QKI K + P ++ P +I+
Sbjct: 198 DGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDP----PIPRWLSPGARTMIK 253
Query: 300 GLLTFDPDSRM 310
+L +P +R+
Sbjct: 254 RMLDPNPVTRI 264
>YOL100w [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1)
Length = 1081
Score = 100 bits (249), Expect = 9e-21
Identities = 70/295 (23%), Positives = 125/295 (41%), Gaps = 62/295 (21%)
Query: 2 SSESHDKVVAKAIRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXX 61
SS++ ++ K I+ ++ IG G+++ V S+ + A K +++
Sbjct: 164 SSKAQKNIIKKGIK----DFKFGSVIGDGAYSTVMLATSIDTKKRYAAKVLNKEYLIRQK 219
Query: 62 XXXXXXVEIAILKKIKH-PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKH 120
+E L+K+ + P +V L + S Y ++EY GD +KK
Sbjct: 220 KVKYVSIEKTALQKLNNSPSVVRLFSTFQDESSLYFLLEYAPNGDFLSLMKK-------- 271
Query: 121 PLIKTVFEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPL 180
+ L+ Y Q+ A+ +L S ++HRDIKP+N+LL +
Sbjct: 272 ----------------YGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLDGEM 315
Query: 181 LDYNDPKTFHELGFVGIYNLPILKIADFGFARFLPNTS------------LAETLCGSPL 228
+K+ DFG A+ L T+ +++ G+
Sbjct: 316 K---------------------IKLTDFGTAKLLNPTNNSVSKPEYDLSTRSKSFVGTAE 354
Query: 229 YMAPEILNYQKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEIT 283
Y++PE+LN + + D+W+ G +L++M G+PPFKA+N FQK+ K T
Sbjct: 355 YVSPELLNDSFTDYRCDIWAFGCILFQMIAGKPPFKATNEYLTFQKVMKVQYAFT 409
>At3g06030 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 651
Score = 100 bits (249), Expect = 9e-21
Identities = 80/333 (24%), Positives = 140/333 (42%), Gaps = 56/333 (16%)
Query: 27 IGKGSFAVVYKGLSLRDGRNIAIKAV-----SRSXXXXXXXXXXXXVEIAILKKIKHPHI 81
IG G+F VY G++L G +AIK V S S E+ +LK + HP+I
Sbjct: 74 IGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNI 133
Query: 82 VGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLN 141
V + R S ++ME+ G ++ ++K F +P P
Sbjct: 134 VRYLGTVRESDSLNILMEFVPGGSISSLLEK--------------FGSFPEP-------- 171
Query: 142 RVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLP 201
+++ Y +QL L++L + ++HRDIK N+L + N
Sbjct: 172 --VIIMYTKQLLLGLEYLHNNGIMHRDIKGANIL---------------------VDNKG 208
Query: 202 ILKIADFGFARF---LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
+++ADFG ++ L + A+++ G+P +MAPE++ ++ AD+WSVG + EM
Sbjct: 209 CIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMAT 268
Query: 259 GRPPFKAS-NHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
G+PP+ I + +P + + P+ + + L +P R+ T+
Sbjct: 269 GKPPWSEQYQQFAAVLHIGRTKAHPPIPED--LSPEAKDFLMKCLHKEPSLRLSATELLQ 326
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDVAESNMFV 350
+ VT +Y L + M V
Sbjct: 327 HPFVTGKRQEPYPAYRNSLTECGNPITTQGMNV 359
>7299793 [T] KOG0583 Serine/threonine protein kinase
Length = 540
Score = 100 bits (249), Expect = 9e-21
Identities = 88/307 (28%), Positives = 136/307 (43%), Gaps = 63/307 (20%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVS-RSXXXXXXXXXXXXVEIAILKKIKHP 79
Y + +G+GS+ V + ++ + +A+K ++ R EIA+LK++KH
Sbjct: 145 YIMGDVLGEGSYGKVKEAMNSENLCRLAVKILTKRKLRRIPNGEQNVTREIALLKQLKHR 204
Query: 80 HIVGLIDC--ERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP---PS 134
H+V L+D YL+MEYC G ++ + ++ P P
Sbjct: 205 HVVELVDVLYNEEKQKMYLVMEYCVGG------------------LQEMIDYQPDKRMPL 246
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
+ +G Y +QL L++L S ++H+DIKP NLLL LD
Sbjct: 247 FQAHG--------YFKQLVDGLEYLHSCRVIHKDIKPGNLLLS---LDQT---------- 285
Query: 195 VGIYNLPILKIADFGFAR----FLPNTSLAETLCGSPLYMAPEILNYQKYNA--KADLWS 248
LKI+DFG A F P+ + T GSP + PEI N + A K D+WS
Sbjct: 286 --------LKISDFGVAEQLDLFAPDDT-CTTGQGSPAFQPPEIANGHETFAGFKVDIWS 336
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCY-IEPKLFNLIRGLLTFDPD 307
G LY + G+ PF+ N L + I + E P+ Y ++ NLI G+L DP
Sbjct: 337 SGVTLYNLATGQYPFEGDNIYRLLENIGRGQWE--APAWLYEMDADFANLILGMLQADPS 394
Query: 308 SRMGFTD 314
R+ +
Sbjct: 395 KRLSLQE 401
>YBR028c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 525
Score = 100 bits (248), Expect = 1e-20
Identities = 78/314 (24%), Positives = 138/314 (43%), Gaps = 68/314 (21%)
Query: 69 EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFE 128
E +IL +I+HP+IV L +S YL+++Y G+L + +K
Sbjct: 202 ERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLK----------------- 244
Query: 129 HYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKT 188
EH L+ V Y ++S AL+FL +K +V+RD+KP+N LL
Sbjct: 245 -------EHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLL------------ 285
Query: 189 FHELGFVGIYNLPILKIADFGFARFLPNTSLAE-----------TLCGSPLYMAPEILNY 237
++ G L + DFG ++ N S + ++ G+P Y APEIL
Sbjct: 286 -NQRGH--------LVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLG 336
Query: 238 QKYNAKADLWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNL 297
+ Y+ D +S+G +LY+M G+PP+ SNH + KI++ +P Y+ + ++
Sbjct: 337 KAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIP--FYLSEGMKDI 394
Query: 298 IRGLLTFDPDSRMGFTDFFNNEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKP 357
+ LL + R ++ T+ ++ K A +++F ++ +
Sbjct: 395 LNALLKKETAKRWNVDKYWAKTGANNKPTKSKK--------KKSGAARTSLFTEHFIFRK 446
Query: 358 L--KQQESAHIPPT 369
+ K ES + T
Sbjct: 447 IDWKLLESGQLQKT 460
>Hs4506735 [T] KOG0603 Ribosomal protein S6 kinase
Length = 772
Score = 100 bits (248), Expect = 1e-20
Identities = 84/298 (28%), Positives = 132/298 (44%), Gaps = 59/298 (19%)
Query: 24 EKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-HPHIV 82
E +G+GSF+V + + G+ A+K +SR E+A L+ + HP++V
Sbjct: 414 EPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQR------EVAALRLCQSHPNVV 467
Query: 83 GLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNR 142
L + YL++E G+L I+K++ H+
Sbjct: 468 NLHEVHHDQLHTYLVLELLRGGELLEHIRKKR--------------HFSESEASQ----- 508
Query: 143 VLVVNYLQQLSSALKFLRSK-NLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLP 201
L+ L SA+ F+ + +VHRD+KP+N+L Y D P
Sbjct: 509 -----ILRSLVSAVSFMHEEAGVVHRDLKPENIL-------YADDTP----------GAP 546
Query: 202 ILKIADFGFARFLPNTSLA--ETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+ KI DFGFAR P + +T C + Y APE+L Q Y+ DLWS+G +LY M G
Sbjct: 547 V-KIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSG 605
Query: 260 RPPFKA-------SNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
+ PF+ S E+ KI++ + + + + L+RGLLT DP R+
Sbjct: 606 QVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRL 663
Score = 62.0 bits (149), Expect = 4e-09
Identities = 65/305 (21%), Positives = 128/305 (41%), Gaps = 53/305 (17%)
Query: 15 RLPTENYSVEKEIGKGSFAVVY---KGLSLRDGRNIAIKAVSRSXXXXXXXXXXXX-VEI 70
++ EN+ + K +G G++ V+ K G+ A+K + ++ E
Sbjct: 27 KVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTER 86
Query: 71 AILKKIKH-PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEH 129
++L+ ++ P +V L +T + +LI++Y + G++ + +R ++
Sbjct: 87 SVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQR--------------QY 132
Query: 130 YPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTF 189
+ G VL + +L +L +++RD+K +N+LL +
Sbjct: 133 FKEAEVRVYGGEIVLALEHLHKLG----------IIYRDLKLENVLLDSE---------- 172
Query: 190 HELGFVGIYNLPILKIADFGFARFLPNTSLAETL--CGSPLYMAPEILNYQKYNAKA-DL 246
+ + DFG ++ T CG+ YMAPEI+ + + KA D
Sbjct: 173 -----------GHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDW 221
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
WS+G +L+E+ G PF ++ + + + P I P +L++ LL DP
Sbjct: 222 WSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDP 281
Query: 307 DSRMG 311
R+G
Sbjct: 282 KKRLG 286
>Hs4506073 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 100 bits (248), Expect = 1e-20
Identities = 84/303 (27%), Positives = 123/303 (39%), Gaps = 54/303 (17%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
L E++ +G+G F V G AIKA+ + E IL
Sbjct: 610 LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAA 669
Query: 76 IK---HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+ HP +V L C +T +MEY A GDL I V P + +F
Sbjct: 670 VTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSD---VFSEP--RAIF----- 719
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
Y + L+FL +V+RD+K NLLL T
Sbjct: 720 ---------------YSACVVLGLQFLHEHKIVYRDLKLDNLLLDTE------------- 751
Query: 193 GFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGT 251
G+V KIADFG + + T CG+P ++APE+L Y D W +G
Sbjct: 752 GYV--------KIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGV 803
Query: 252 VLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
+LYEM G PF + E+F I NDE+ P ++ + ++R LL +P+ R+G
Sbjct: 804 LLYEMLVGESPFPGDDEEEVFDSI--VNDEVRYPR--FLSAEAIGIMRRLLRRNPERRLG 859
Query: 312 FTD 314
++
Sbjct: 860 SSE 862
>Hs14758219 [T] KOG0694 Serine/threonine protein kinase
Length = 942
Score = 100 bits (248), Expect = 1e-20
Identities = 84/303 (27%), Positives = 123/303 (39%), Gaps = 54/303 (17%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
L E++ +G+G F V G AIKA+ + E IL
Sbjct: 610 LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAA 669
Query: 76 IK---HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+ HP +V L C +T +MEY A GDL I V P + +F
Sbjct: 670 VTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSD---VFSEP--RAIF----- 719
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
Y + L+FL +V+RD+K NLLL T
Sbjct: 720 ---------------YSACVVLGLQFLHEHKIVYRDLKLDNLLLDTE------------- 751
Query: 193 GFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGT 251
G+V KIADFG + + T CG+P ++APE+L Y D W +G
Sbjct: 752 GYV--------KIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGV 803
Query: 252 VLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMG 311
+LYEM G PF + E+F I NDE+ P ++ + ++R LL +P+ R+G
Sbjct: 804 LLYEMLVGESPFPGDDEEEVFDSI--VNDEVRYPR--FLSAEAIGIMRRLLRRNPERRLG 859
Query: 312 FTD 314
++
Sbjct: 860 SSE 862
>Hs14670383 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 370
Score = 100 bits (248), Expect = 1e-20
Identities = 65/258 (25%), Positives = 118/258 (45%), Gaps = 44/258 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXV---EIAILKKIK 77
Y + +E+G G FA+V K G A K + + E++IL+++
Sbjct: 23 YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVL 82
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
H +++ L D +D LI+E + G+L F+ ++++L S E
Sbjct: 83 HHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESL-----------------SEEE 125
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
++++Q+ + +L +K + H D+KP+N++L LD N P
Sbjct: 126 -------ATSFIKQILDGVNYLHTKKIAHFDLKPENIML----LDKNIP----------- 163
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+P +K+ DFG A + + + + G+P ++APEI+NY+ +AD+WS+G + Y +
Sbjct: 164 --IPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILL 221
Query: 258 CGRPPFKASNHLELFQKI 275
G PF E I
Sbjct: 222 SGASPFLGDTKQETLANI 239
>CE22877 [D] KOG0575 Polo-like serine/threonine protein kinase
Length = 632
Score = 100 bits (248), Expect = 1e-20
Identities = 79/289 (27%), Positives = 125/289 (42%), Gaps = 49/289 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y K +GKG FA Y+ + G A K V ++ E+ I + ++H +
Sbjct: 36 YEKGKFLGKGGFAHCYELRNKSTGELFAGKVVPKALLIKQYQRDKMAQEVQIHRNLQHRN 95
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
+V L S+ Y+ +E C R++L+ H K V E P +
Sbjct: 96 VVKLYHFFEDKSNVYITLELCP----------RRSLMELHKRRKAVTE----PEARY--- 138
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
+ Q+ + +L + +VHRD+K NL L L
Sbjct: 139 -------FTYQIVEGVLYLHNLKIVHRDLKLGNLFLNDELQ------------------- 172
Query: 201 PILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGR 260
+KI DFG A N +TLCG+P Y+APE+LN ++ + DLW++G +LY + G
Sbjct: 173 --VKIGDFGLATTCDNDERKKTLCGTPNYIAPEVLNKIGHSFEVDLWAIGCILYILLFGH 230
Query: 261 PPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
PPF++ + E + +IK N+ +P++ LIR LL P R
Sbjct: 231 PPFESKSLEETYSRIK--NNNYVIPTSA--SAAASQLIRVLLDPVPSRR 275
>At3g07980 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1367
Score = 100 bits (248), Expect = 1e-20
Identities = 101/417 (24%), Positives = 172/417 (41%), Gaps = 71/417 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + EIGKG++ VY GL L +G +AIK VS EI +LK + H +
Sbjct: 20 YMLGDEIGKGAYGRVYIGLDLENGDFVAIKQVSLENIGQEDLNTIMQ-EIDLLKNLNHKN 78
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV + +T + ++I+EY G L IK K F +P
Sbjct: 79 IVKYLGSLKTKTHLHIILEYVENGSLANIIKPNK------------FGPFPES------- 119
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
LV Y+ Q+ L +L + ++HRDIK N+L L
Sbjct: 120 ---LVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL------------------- 157
Query: 201 PILKIADFGFARFLPNTSL-AETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+K+ADFG A L ++ G+P +MAPE++ A +D+WSVG + E+
Sbjct: 158 --VKLADFGVATKLNEADFNTHSVVGTPYWMAPEVIELSGVCAASDIWSVGCTIIELLTC 215
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR--------MG 311
PP+ + +I + +D +P + + P + + +R L F DSR +
Sbjct: 216 VPPYYDLQPMPALYRIVQ-DDTPPIPDS--LSPDITDFLR--LCFKKDSRQRPDAKTLLS 270
Query: 312 FTDFFNNEVVTEDLTRYEQS--YEPDLESKSKDVAESNMFVSEYL----VKPLKQQESAH 365
N+ R+ + Y + +S S+ AE + V E + V+ K +
Sbjct: 271 HPWIRNSRRALRSSLRHSGTIRYMKETDSSSEKDAEGSQEVVESVSAEKVEVTKTNSKSK 330
Query: 366 IP-------PTQTDENTSVQTGVRRTSGKERLATNHPPHQQIHPEDNSQNPEQSYQS 415
+P ++ D+++ G T ++ + ++ P +H + + Q+ S S
Sbjct: 331 LPVIGGASFRSEKDQSSPSDLGEEGTDSEDDINSDQGPTLSMHDKSSRQSGTCSISS 387
>YMR104c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 677
Score = 99.8 bits (247), Expect = 2e-20
Identities = 84/334 (25%), Positives = 141/334 (42%), Gaps = 59/334 (17%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
L +++ + K IGKGSF V + + A+KA+ ++ E +L +
Sbjct: 339 LSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLAR 398
Query: 76 IKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPST 135
+ P IV L ++ YL++ + G+L + ++ L
Sbjct: 399 VDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRF------------ 446
Query: 136 EHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFV 195
Y+ +L AL L ++++RD+KP+N+ LLDY
Sbjct: 447 ------------YIAELLCALDSLHKLDVIYRDLKPENI-----LLDYQGH--------- 480
Query: 196 GIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLY 254
+ + DFG + + + +T CG+P Y+APEIL Q Y D W++G +LY
Sbjct: 481 -------IALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLY 533
Query: 255 EMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGF-- 312
EM G PP+ N +++KI + P +P +L+ GLL+ DP R+G
Sbjct: 534 EMMTGLPPYYDENVPVMYKKI--LQQPLLFPDG--FDPAAKDLLIGLLSRDPSRRLGVNG 589
Query: 313 TDFFNNEVVTED-------LTRYEQSYEPDLESK 339
TD N +D L Y Y+P ++S+
Sbjct: 590 TDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSE 623
>Hs20149547 [T] KOG0603 Ribosomal protein S6 kinase
Length = 735
Score = 99.8 bits (247), Expect = 2e-20
Identities = 100/410 (24%), Positives = 176/410 (42%), Gaps = 68/410 (16%)
Query: 9 VVAKAIRLPTENYSVEKEIGKGSFAVVY--KGLSLRDGRNIAIKAVSRSXXXXXXXXXXX 66
V A + + ++ + K +G+GSF V+ + ++ D ++ V +
Sbjct: 50 VKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRT 109
Query: 67 XVEIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTV 126
+E IL + HP +V L +T YLI+++ GDL F + K ++ +K
Sbjct: 110 KMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDL--FTRLSKEVMFTEEDVKF- 166
Query: 127 FEHYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDP 186
YL +L+ L L S +++RD+KP+N+LL
Sbjct: 167 ---------------------YLAELALGLDHLHSLGIIYRDLKPENILL---------- 195
Query: 187 KTFHELGFVGIYNLPILKIADFGFAR-FLPNTSLAETLCGSPLYMAPEILNYQKYNAKAD 245
E G + K+ DFG ++ + + A + CG+ YMAPE++N Q ++ AD
Sbjct: 196 ---DEEGHI--------KLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSAD 244
Query: 246 LWSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFD 305
WS G +++EM G PF+ + E I KA ++ +P ++ + +L+R L +
Sbjct: 245 WWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA--KLGMPQ--FLSTEAQSLLRALFKRN 300
Query: 306 PDSRMGFTDFFNNEV------VTEDLTR-YEQSYEPDLESKSKDVAESNMFVSEYLVKPL 358
P +R+G E+ T D + Y + +P + ++ F +E+ +
Sbjct: 301 PANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTP 360
Query: 359 KQQESAHIPPTQTDEN-----TSVQTGVRRTSGKERL--ATNHPPHQQIH 401
K +S IPP+ + V TG+ GK R A H QQ+H
Sbjct: 361 K--DSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHSVVQQLH 408
Score = 80.9 bits (198), Expect = 8e-15
Identities = 81/317 (25%), Positives = 133/317 (41%), Gaps = 65/317 (20%)
Query: 18 TENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK 77
++ Y V++ IG GS++ + + A+K + +S +EI +L+ +
Sbjct: 415 SDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEE-----IEI-LLRYGQ 468
Query: 78 HPHIVGLIDCERTSSDFYLIMEYCALGDLT-------FFIKKRKNLVLKHPLIKTVFEHY 130
HP+I+ L D YL+ E G+L FF ++ + VL H + KTV
Sbjct: 469 HPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVL-HTIGKTV---- 523
Query: 131 PPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFH 190
++L S+ +VHRD+KP N+L Y D
Sbjct: 524 --------------------------EYLHSQGVVHRDLKPSNIL-------YVD----- 545
Query: 191 ELGFVGIYNLPILKIADFGFARFL-PNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSV 249
E G N L+I DFGFA+ L L T C + ++APE+L Q Y+ D+WS+
Sbjct: 546 ESG-----NPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSL 600
Query: 250 GTVLYEMCCGRPPF---KASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
G +LY M G PF + E+ +I ++ + + +L+ +L DP
Sbjct: 601 GILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDP 660
Query: 307 DSRMGFTDFFNNEVVTE 323
R+ + VT+
Sbjct: 661 HQRLTAKQVLQHPWVTQ 677
>At1g76040 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 534
Score = 99.8 bits (247), Expect = 2e-20
Identities = 74/304 (24%), Positives = 128/304 (41%), Gaps = 44/304 (14%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIK-HP 79
Y + KE+G+G F + YK +GR A K++S+ E+ IL+ + P
Sbjct: 85 YDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQP 144
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV + +L+ME C+ G+L I K+ + K
Sbjct: 145 NIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKE------------------- 185
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
N +Q+ + + +VHRD+KP+N LL + + + P
Sbjct: 186 -----AANIFRQIVNVVHVCHFMGVVHRDLKPENFLLVSN--EEDSP------------- 225
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+K DFG + F+ + + GS Y+APE+L ++ Y + D+WS G +LY + G
Sbjct: 226 ---IKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVL-HRNYGKEIDVWSAGVMLYILLSG 281
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNNE 319
PPF +F+ I + ++ I +LIR +L DP R+ + +
Sbjct: 282 VPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHP 341
Query: 320 VVTE 323
+T+
Sbjct: 342 WMTD 345
>SPACUNK12.02c [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 335
Score = 99.4 bits (246), Expect = 2e-20
Identities = 80/309 (25%), Positives = 136/309 (43%), Gaps = 52/309 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKI--KH 78
Y V + +G G++A V + + + + A K +++ EIAILK++ +H
Sbjct: 31 YRVGRVLGGGTYATVREAVHIETNKMYAAKIMNKKMMEKKQDFVKN--EIAILKRVSYEH 88
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+I+ L+D T ++ YLI E G+L F+ + +
Sbjct: 89 PNILHLVDFFETVNNLYLITELATGGEL--------------------FDRICAKGSFYE 128
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
L ++ +SA+K+L +VHRD+KP+NLL + DP +
Sbjct: 129 ADAAAL----MRTTTSAVKYLHDNGIVHRDLKPENLLYRS-----KDPNSD--------- 170
Query: 199 NLPILKIADFGFARFLPNTS--LAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEM 256
L IADFG + F ++ + T CG+P YMAPE+ Y D+W++G + Y +
Sbjct: 171 ----LLIADFGLSHFYEDSQYYMLMTACGTPEYMAPEVFRRTGYGKPVDMWAIGVITYFL 226
Query: 257 CCGRPPFKASNHLELFQKIKKANDEITVPSNCY--IEPKLFNLIRGLLTFDPDSRMGFTD 314
G PF + +E+ + I +E T C+ I + I+ L DP R+ D
Sbjct: 227 LSGYTPFARPSQVEVIEAI--LANEYTFNDPCWSGISETAKDFIKKCLENDPSKRLTAAD 284
Query: 315 FFNNEVVTE 323
+ ++E
Sbjct: 285 ALKHPFLSE 293
>SPAC1B9.02c [RT] KOG0598 Ribosomal protein S6 kinase and related proteins
Length = 696
Score = 99.4 bits (246), Expect = 2e-20
Identities = 81/303 (26%), Positives = 139/303 (45%), Gaps = 53/303 (17%)
Query: 14 IRLPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAIL 73
+R E+++ + IGKG+F VY R A+K +S+ E IL
Sbjct: 295 VRYGPEDFTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNIL 354
Query: 74 KKI---KHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHY 130
+ + P IVGL +T+SD YLI +Y + G+L + ++ + P + F
Sbjct: 355 VRTSLDESPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEG----RFPEQRAKF--- 407
Query: 131 PPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFH 190
Y+ +L AL+ L ++++RD+KP+N+LL
Sbjct: 408 -----------------YIAELVLALEHLHKHDIIYRDLKPENILLDAD----------- 439
Query: 191 ELGFVGIYNLPILKIADFGFARF-LPNTSLAETLCGSPLYMAPEILNYQK-YNAKADLWS 248
G + + DFG ++ L + T CG+ Y+APE+L K Y + D WS
Sbjct: 440 --GHIA--------LCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKGYTKQVDFWS 489
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G +++EMCCG PF A + ++++ I A ++ P + + + +RGLL +P+
Sbjct: 490 LGVLVFEMCCGWSPFYAPDVQQMYRNI--AFGKVRFPKG-VLSSEGRSFVRGLLNRNPNH 546
Query: 309 RMG 311
R+G
Sbjct: 547 RLG 549
>Hs4502709 [R] KOG0594 Protein kinase PCTAIRE and related kinases
Length = 297
Score = 99.4 bits (246), Expect = 2e-20
Identities = 74/271 (27%), Positives = 129/271 (47%), Gaps = 52/271 (19%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E+Y+ ++IG+G++ VVYKG G+ +A+K + R EI++LK+++H
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKI-RLESEEEGVPSTAIREISLLKELRH 60
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV L D S YLI E+ ++ +K + PP
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMD------------------LKKYLDSIPPGQY--- 99
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
++ LV +YL Q+ + F S+ ++HRD+KPQNLL+ +D T
Sbjct: 100 -MDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLI-------DDKGT---------- 141
Query: 199 NLPILKIADFGFARF--LPNTSLAETLCGSPLYMAPEI-LNYQKYNAKADLWSVGTVLYE 255
+K+ADFG AR +P + + Y +PE+ L +Y+ D+WS+GT+ E
Sbjct: 142 ----IKLADFGLARAFGIPIRVYTHEVV-TLWYRSPEVLLGSARYSTPVDIWSIGTIFAE 196
Query: 256 MCCGRPPFKASNHLE----LFQKIKKANDEI 282
+ +P F + ++ +F+ + N+E+
Sbjct: 197 LATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
>Hs14042947 [T] KOG0583 Serine/threonine protein kinase
Length = 367
Score = 99.4 bits (246), Expect = 2e-20
Identities = 90/310 (29%), Positives = 136/310 (43%), Gaps = 54/310 (17%)
Query: 16 LPTENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKK 75
L Y + +G+GS+A V S R N+AIK + R EI IL
Sbjct: 7 LKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAM 66
Query: 76 IKHPHIVGLIDCERTS-SDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPS 134
+ H I+ + TS Y++ME GDL IK R L
Sbjct: 67 LNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGAL------------------ 108
Query: 135 TEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGF 194
H R QLS A+K+ ++VHRD+K NLLL D+N
Sbjct: 109 --HEDEAR----KKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDK---DFN---------- 149
Query: 195 VGIYNLPILKIADFGFA-RFLPNTS----LAETLCGSPLYMAPEILNYQKYNAKA-DLWS 248
+K++DF F+ R L + S L++T CGSP Y APE+L Y K D+WS
Sbjct: 150 --------IKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWS 201
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G +LY M CG P+ SN ++ +I+K + + P + ++ + +LI +L D +
Sbjct: 202 LGVILYIMVCGSMPYDDSN-IKKMLRIQKEH-RVNFPRSKHLTGECKDLIYHMLQPDVNR 259
Query: 309 RMGFTDFFNN 318
R+ + ++
Sbjct: 260 RLHIDEILSH 269
>CE27166 [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA)
Length = 270
Score = 99.4 bits (246), Expect = 2e-20
Identities = 68/243 (27%), Positives = 119/243 (47%), Gaps = 51/243 (20%)
Query: 69 EIAILKKIKHPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFE 128
E +L ++KHP IV + E+ S+ Y+IME+ G++ +++ ++
Sbjct: 10 EKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSF------------ 57
Query: 129 HYPPPSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKT 188
N + R Y ++ AL+++ S +V+RD+KP+NL+L K
Sbjct: 58 --------SNSMARF----YASEIVCALEYIHSLGIVYRDLKPENLMLS---------KE 96
Query: 189 FHELGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWS 248
H +K+ADFGFA+ L + + T+CG+P Y+APE L +N D W+
Sbjct: 97 GH------------IKMADFGFAKELRDRTY--TICGTPDYLAPESLARTGHNKGVDWWA 142
Query: 249 VGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDS 308
+G ++YEM G+PPF+ E++ I ++ P + + K +L++ LL D
Sbjct: 143 LGILIYEMMVGKPPFRGKTTSEIYDAI--IEHKLKFPRSFNLAAK--DLVKKLLEVDRTQ 198
Query: 309 RMG 311
R+G
Sbjct: 199 RIG 201
>CE02377 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 1211
Score = 99.4 bits (246), Expect = 2e-20
Identities = 73/291 (25%), Positives = 124/291 (42%), Gaps = 47/291 (16%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y V K +G G F VY + G+ A K + E++IL +++HP
Sbjct: 45 YQVTKLLGDGKFGKVYCVIEKETGKEFAAKFIKIRKEADRAEVER---EVSILTQLRHPR 101
Query: 81 IVGLIDC-ERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
I + D T++D LIME G+L + + E
Sbjct: 102 IAQIYDAFYTTTNDVVLIMEIVRGGEL-----------------------FDRVAEESYV 138
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
L+ + VV + QL A+ ++ +N++H D+KP+N++ C L
Sbjct: 139 LSELAVVMIICQLCEAIDYIHKQNILHLDVKPENIM-CVSLTGNR--------------- 182
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+K+ DFG AR T + + G+P + APE++ ++K + D+WS+G + Y + G
Sbjct: 183 ---IKLIDFGLARHYDGTQELKYMAGTPEFAAPEVIKFEKLDYHTDMWSIGVITYILLSG 239
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PF N E + ++K E T + E + + + LL +D RM
Sbjct: 240 YSPFLGDNLGETYCNVEKGVWEFTEEFDTVTE-EAKDFVTKLLVYDQSKRM 289
>At5g19450 [T] KOG0032 Ca2+/calmodulin-dependent protein kinase EF-Hand
protein superfamily
Length = 533
Score = 99.4 bits (246), Expect = 2e-20
Identities = 74/291 (25%), Positives = 119/291 (40%), Gaps = 44/291 (15%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKI-KHP 79
Y + +E+G+G F + Y ++ G A K++S+ E+ I+K + +HP
Sbjct: 57 YDLGREVGRGEFGITYLCTDIKTGEKYACKSISKKKLRTAVDIEDVRREVEIMKHMPRHP 116
Query: 80 HIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNG 139
+IV L D +++ME C G+L I R HY TE
Sbjct: 117 NIVSLKDAFEDDDAVHIVMELCEGGELFDRIVAR--------------GHY----TER-- 156
Query: 140 LNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYN 199
++ + ++ ++HRD+KP+N L F
Sbjct: 157 ----AAAAVMKTILEVVQICHKHGVMHRDLKPENFL------------------FANKKE 194
Query: 200 LPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
LK DFG + F + GSP YMAPE+L + Y + D+WS G +LY + CG
Sbjct: 195 TSALKAIDFGLSVFFKPGEGFNEIVGSPYYMAPEVLR-RNYGPEVDIWSAGVILYILLCG 253
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRM 310
PPF A + Q I ++ + + +L+R +L DP R+
Sbjct: 254 VPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSETAKDLVRKMLEPDPKKRL 304
>At3g20860 [R] KOG0589 Serine/threonine protein kinase
Length = 427
Score = 99.4 bits (246), Expect = 2e-20
Identities = 70/291 (24%), Positives = 126/291 (43%), Gaps = 47/291 (16%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
++Y V ++IG+G+F + + + R +K + R E++++ K+K
Sbjct: 13 DDYEVVEQIGRGAFGSAFLVIHKSERRKYVVKKI-RLAKQTERCKLAAIQEMSLISKLKS 71
Query: 79 PHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHN 138
P+IV D ++ YC GD+T IKK + + +
Sbjct: 72 PYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGVFASEEKL--------------- 116
Query: 139 GLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIY 198
++ QL A+ +L + ++HRD+K N+ L N+
Sbjct: 117 -------CRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLTKE----NE------------- 152
Query: 199 NLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCC 258
+++ DFG A+ L LA ++ G+P YM PE+L Y K+D+WS+G ++E+
Sbjct: 153 ----VRLGDFGLAKLLGKDDLASSMVGTPNYMCPELLADIPYGYKSDIWSLGCCMFEVAA 208
Query: 259 GRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
+P FKA + L KI +++ P L LI+ +L +P+ R
Sbjct: 209 HQPAFKAPDMAALINKINRSS---LSPLPVMYSSSLKRLIKSMLRKNPEHR 256
>SPAC644.06c [D] KOG0588 Serine/threonine protein kinase
Length = 593
Score = 99.0 bits (245), Expect = 3e-20
Identities = 78/295 (26%), Positives = 127/295 (42%), Gaps = 56/295 (18%)
Query: 25 KEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPHIVGL 84
K +G GS + V + G AIK + +EI +++ ++HP+I+ L
Sbjct: 16 KTLGTGSTSCVRLAKHAKTGDLAAIKIIP-------IRYASIGMEILMMRLLRHPNILRL 68
Query: 85 IDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGLNRVL 144
D YL +EY G+L +I+K H L+
Sbjct: 69 YDVWTDHQHMYLALEYVPDGELFHYIRK------------------------HGPLSERE 104
Query: 145 VVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNLPILK 204
+YL Q+ A+ HRD+K +N+L+ N +K
Sbjct: 105 AAHYLSQILDAVAHCHRFRFRHRDLKLENILIKV--------------------NEQQIK 144
Query: 205 IADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKY-NAKADLWSVGTVLYEMCCGRPPF 263
IADFG A PN S E CGS Y+APEI++++ Y A AD+WS G +LY + + PF
Sbjct: 145 IADFGMATVEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLLSNKLPF 204
Query: 264 KASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFNN 318
N ++ KI+ + +PS+ I +L+ +L +P +R+ + F++
Sbjct: 205 GGQNTDVIYNKIR--HGAYDLPSS--ISSAAQDLLHRMLDVNPSTRITIPEVFSH 255
>Hs4505785 [G] KOG0599 Phosphorylase kinase gamma subunit
Length = 406
Score = 99.0 bits (245), Expect = 3e-20
Identities = 77/304 (25%), Positives = 130/304 (42%), Gaps = 57/304 (18%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIK-----AVSRSXXXXXXXXXXXXVEIAIL 73
+ Y + IG+G +VV + + G A+K A S E IL
Sbjct: 22 QKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHIL 81
Query: 74 KKIK-HPHIVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPP 132
+++ HPHI+ LID +SS +L+ + G+L ++
Sbjct: 82 RQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL---------------------- 119
Query: 133 PSTEHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHEL 192
TE L+ + ++ L A+ FL + N+VHRD+KP+N+LL +
Sbjct: 120 --TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQ----------- 166
Query: 193 GFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEIL------NYQKYNAKADL 246
++++DFGF+ L LCG+P Y+APEIL + Y + DL
Sbjct: 167 ----------IRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDL 216
Query: 247 WSVGTVLYEMCCGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDP 306
W+ G +L+ + G PPF + + + I + + + P + +LI LL DP
Sbjct: 217 WACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDP 276
Query: 307 DSRM 310
++R+
Sbjct: 277 EARL 280
>At5g28290 [R] KOG0589 Serine/threonine protein kinase
Length = 568
Score = 99.0 bits (245), Expect = 3e-20
Identities = 92/396 (23%), Positives = 157/396 (39%), Gaps = 68/396 (17%)
Query: 19 ENYSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKH 78
E+Y V ++IGKGSF + + +K + R E+ ++ KI++
Sbjct: 2 EHYEVLEQIGKGSFGSALLVRHKHEKKLYVLKKI-RLARQTGRTRRSAHQEMELISKIRN 60
Query: 79 PHIVGLIDCERTSSDFY-LIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEH 137
P IV D + +++ YC GD+ IKK + +
Sbjct: 61 PFIVEYKDSWVEKGCYVCIVIGYCKGGDMAEAIKKANGVEFSEEKL-------------- 106
Query: 138 NGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGI 197
+L QL AL++L + +++HRD+K N+ L
Sbjct: 107 --------CKWLVQLLMALEYLHASHILHRDVKCSNIFLTKD------------------ 140
Query: 198 YNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMC 257
+++ DFG A+ L + LA ++ G+P YM PE+L Y +K+D+WS+G +YEM
Sbjct: 141 ---QDIRLGDFGLAKILTSDDLASSVVGTPSYMCPELLADIPYGSKSDIWSLGCCMYEMT 197
Query: 258 CGRPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSRMGFTDFFN 317
+P FKA + L +I N I P +L++ +L +P+ R +D
Sbjct: 198 ALKPAFKAFDMQGLINRI---NRSIVAPLPAQYSTAFRSLVKSMLRKNPELRPSASDLLR 254
Query: 318 NEVVTEDLTRYEQSYEPDLESKSKDVAESNMFVSEYLVKPLKQQESAHIPPTQTDENTSV 377
+ L Y Q L + D S ++ S++ + SV
Sbjct: 255 QPL----LQPYVQKVLLKLSFREHDTLPSE-----------SERRSSYPQQRKRTSGKSV 299
Query: 378 QTGVRR--TSGKERLATNHPPHQQIH---PEDNSQN 408
G R ++ +++ P H +H P D S N
Sbjct: 300 SFGPSRFGVDQEDSVSSVKPVHTYLHRHRPVDLSAN 335
>At3g13530 [T] KOG0198 MEKK and related serine/threonine protein kinases
Length = 1368
Score = 99.0 bits (245), Expect = 3e-20
Identities = 81/290 (27%), Positives = 127/290 (42%), Gaps = 50/290 (17%)
Query: 21 YSVEKEIGKGSFAVVYKGLSLRDGRNIAIKAVSRSXXXXXXXXXXXXVEIAILKKIKHPH 80
Y + EIGKG++ VYKGL L +G +AIK VS EI +LK + H +
Sbjct: 20 YMLGDEIGKGAYGRVYKGLDLENGDFVAIKQVSLENIVQEDLNTIMQ-EIDLLKNLNHKN 78
Query: 81 IVGLIDCERTSSDFYLIMEYCALGDLTFFIKKRKNLVLKHPLIKTVFEHYPPPSTEHNGL 140
IV + +T + ++I+EY G L IK K F +P
Sbjct: 79 IVKYLGSSKTKTHLHIILEYVENGSLANIIKPNK------------FGPFPES------- 119
Query: 141 NRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLCTPLLDYNDPKTFHELGFVGIYNL 200
LV Y+ Q+ L +L + ++HRDIK N+L L
Sbjct: 120 ---LVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL------------------- 157
Query: 201 PILKIADFGFARFLPNTSL-AETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCG 259
+K+ADFG A L + ++ G+P +MAPE++ A +D+WSVG + E+
Sbjct: 158 --VKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLTC 215
Query: 260 RPPFKASNHLELFQKIKKANDEITVPSNCYIEPKLFNLIRGLLTFDPDSR 309
PP+ + +I + +D +P + + P + + +R F DSR
Sbjct: 216 VPPYYDLQPMPALFRIVQ-DDNPPIPDS--LSPDITDFLR--QCFKKDSR 260
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,105,451
Number of Sequences: 60738
Number of extensions: 1976828
Number of successful extensions: 12396
Number of sequences better than 1.0e-05: 1522
Number of HSP's better than 0.0 without gapping: 304
Number of HSP's successfully gapped in prelim test: 1223
Number of HSP's that attempted gapping in prelim test: 7852
Number of HSP's gapped (non-prelim): 2262
length of query: 831
length of database: 30,389,216
effective HSP length: 115
effective length of query: 716
effective length of database: 23,404,346
effective search space: 16757511736
effective search space used: 16757511736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)