ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4364 check: MH L KOG0478 Replication, recombination and repair DNA replication licensing factor, MCM4 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4364 1540385 1537710 -892
(892 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPR019w [L] KOG0478 DNA replication licensing factor MCM4 component 1248 0.0
Hs14738665 [L] KOG0478 DNA replication licensing factor MCM4 com... 653 0.0
At2g16440 [L] KOG0478 DNA replication licensing factor MCM4 comp... 648 0.0
7304207 [L] KOG0478 DNA replication licensing factor MCM4 component 629 e-180
CE21767 [L] KOG0478 DNA replication licensing factor MCM4 component 607 e-173
ECU02g1150 [L] KOG0478 DNA replication licensing factor MCM4 com... 546 e-155
SPCC16A11.17 [L] KOG0478 DNA replication licensing factor MCM4 c... 497 e-140
SPBC25D12.03c [L] KOG0482 DNA replication licensing factor MCM7 ... 368 e-101
SPBC211.04c [L] KOG0480 DNA replication licensing factor MCM6 co... 362 1e-99
CE09874 [L] KOG0482 DNA replication licensing factor MCM7 component 350 6e-96
At4g02060 [L] KOG0482 DNA replication licensing factor MCM7 comp... 350 7e-96
CE19038 [L] KOG0477 DNA replication licensing factor MCM2 component 348 2e-95
YGL201c [L] KOG0480 DNA replication licensing factor MCM6 component 347 5e-95
Hs20535929 [L] KOG0477 DNA replication licensing factor MCM2 com... 346 1e-94
SPAC3F10.01 [L] KOG0481 DNA replication licensing factor MCM5 co... 345 2e-94
7299005 [L] KOG0477 DNA replication licensing factor MCM2 component 345 2e-94
YBR202w [L] KOG0482 DNA replication licensing factor MCM7 component 345 2e-94
At5g46280 [L] KOG0479 DNA replication licensing factor MCM3 comp... 342 2e-93
Hs21359886 [L] KOG0482 DNA replication licensing factor MCM7 com... 340 4e-93
At2g07690 [L] KOG0481 DNA replication licensing factor MCM5 comp... 338 3e-92
SPCC1682.02c [L] KOG0479 DNA replication licensing factor MCM3 c... 337 6e-92
YLR274w [L] KOG0481 DNA replication licensing factor MCM5 component 335 1e-91
ECU05g0780 [L] KOG0480 DNA replication licensing factor MCM6 com... 335 1e-91
CE00415 [L] KOG0480 DNA replication licensing factor MCM6 component 333 5e-91
7299365 [L] KOG0481 DNA replication licensing factor MCM5 component 333 9e-91
7295030 [L] KOG0482 DNA replication licensing factor MCM7 component 330 8e-90
CE03558 [L] KOG0481 DNA replication licensing factor MCM5 component 329 1e-89
SPBC4.04c [L] KOG0477 DNA replication licensing factor MCM2 comp... 328 3e-89
7290738 [L] KOG0480 DNA replication licensing factor MCM6 component 328 3e-89
At1g44900 [L] KOG0477 DNA replication licensing factor MCM2 comp... 325 2e-88
Hs7427519 [L] KOG0480 DNA replication licensing factor MCM6 comp... 324 4e-88
Hs6631095 [L] KOG0479 DNA replication licensing factor MCM3 comp... 322 2e-87
HsM14149623 [L] KOG0482 DNA replication licensing factor MCM7 co... 320 6e-87
YBL023c [L] KOG0477 DNA replication licensing factor MCM2 component 319 1e-86
Hs11418031 [L] KOG0481 DNA replication licensing factor MCM5 com... 318 2e-86
ECU06g0340 [L] KOG0481 DNA replication licensing factor MCM5 com... 318 2e-86
Hs6981192 [L] KOG0481 DNA replication licensing factor MCM5 comp... 315 2e-85
Hs4758706 [L] KOG0477 DNA replication licensing factor MCM2 comp... 314 3e-85
ECU04g0850 [L] KOG0477 DNA replication licensing factor MCM2 com... 311 4e-84
ECU09g1360 [L] KOG0482 DNA replication licensing factor MCM7 com... 310 8e-84
CE08392 [L] KOG0479 DNA replication licensing factor MCM3 component 308 2e-83
YEL032w [L] KOG0479 DNA replication licensing factor MCM3 component 302 1e-81
ECU08g0290 [L] KOG0479 DNA replication licensing factor MCM3 com... 299 1e-80
7290573 [L] KOG0479 DNA replication licensing factor MCM3 component 295 3e-79
Hs19923727 [L] KOG0480 DNA replication licensing factor MCM6 com... 284 5e-76
At3g09660 [L] KOG0480 DNA replication licensing factor MCM6 comp... 279 1e-74
ECU11g0800 [L] KOG0480 DNA replication licensing factor MCM6 com... 227 5e-59
ECU07g0490 [L] KOG0478 DNA replication licensing factor MCM4 com... 184 5e-46
At2g14050 [L] KOG0477 DNA replication licensing factor MCM2 comp... 166 1e-40
7300061 [L] KOG0478 DNA replication licensing factor MCM4 component 150 8e-36
Hs22056246 [L] KOG0477 DNA replication licensing factor MCM2 com... 70 1e-11
>YPR019w [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 933
Score = 1248 bits (3228), Expect = 0.0
Identities = 612/796 (76%), Positives = 708/796 (88%), Gaps = 2/796 (0%)
Query: 99 INASDLSSPRRIVTFXXXXXXXXXXXXXXRPASEAADQPLKIIWGTNVSIQECGNSFREF 158
I+ SDLSSPRRIV F A +PL+IIWGTNVSIQEC +FR F
Sbjct: 138 IHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRIIWGTNVSIQECTTNFRNF 197
Query: 159 LMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKL 218
LMSFK K+RK LD++E FIN TTD+ELYY+ QLN+MR+LGTSNLNLD RNLLAYK TE L
Sbjct: 198 LMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDL 257
Query: 219 FHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVETKKGMREL 278
+HQ+L YPQE+I+IMDQT+KDCMVSL +DN L+ L+EIE+K +KVRPYNV + KGMREL
Sbjct: 258 YHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMREL 317
Query: 279 NPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVCN 338
NPNDIDKL+++KGLVLRSTP+IPDM VAFFKCNVC+HT+ VEIDRG+IQEP RC R+ CN
Sbjct: 318 NPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCN 377
Query: 339 SPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSG 398
PNSM L+HNRC+F D+QVIKLQETPD VPDGQTPHS+SLCVYDELVDSCRAGDRIEV+G
Sbjct: 378 EPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTG 437
Query: 399 IFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDN--VEE 456
FRSIPIR+N +QR LKSLYKTY+DVVH++KV+ R+ VDTST+EQ+L+QN++D+ VEE
Sbjct: 438 TFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEE 497
Query: 457 IRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGR 516
+R ++ +D+ +I+E A R D+Y +L+RSIAPSIYEL+DVKKGILLQLFGG NKTF KGGR
Sbjct: 498 VRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGR 557
Query: 517 YRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLE 576
YRGDINILLCGDPSTSKSQILQYVHKI PRGVYTSGKGSSAVGLTAY+TRDVDTKQLVLE
Sbjct: 558 YRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLE 617
Query: 577 SGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANP 636
SGALVLSDGGVCCIDEFDKM+D+TRSVLHEVMEQQTISIAKAGIITTLNAR+SILASANP
Sbjct: 618 SGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANP 677
Query: 637 INSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVS 696
I SRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKV+E +DRELAKHLT+LYLED+P+ +S
Sbjct: 678 IGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHIS 737
Query: 697 QGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQ 756
Q D+LPVEFLT YI+YAK++IHP+ITE+AKTELVRAYVGMRKMGDDSRSDEKRITATTRQ
Sbjct: 738 QDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQ 797
Query: 757 LESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDMNLVQTGKSVV 816
LESMIRL+EAHAKM+L VELEDV+EAVRLI+SAIKDYATDPKTGKIDMNLVQTGKSV+
Sbjct: 798 LESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVI 857
Query: 817 QRKLLEDLAREILKILTERTTDTISFNELSKLINEQSQDKVESIELSNALTRLQQEDKVV 876
QRKL EDL+REI+ +L ++ +D++SFNEL K INE SQD+VES ++ AL+RLQQEDKV+
Sbjct: 858 QRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDKVI 917
Query: 877 ILGEGLRRSIRLNGRV 892
+LGEG+RRS+RLN RV
Sbjct: 918 VLGEGVRRSVRLNNRV 933
>Hs14738665 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 863
Score = 653 bits (1684), Expect = 0.0
Identities = 354/757 (46%), Positives = 498/757 (65%), Gaps = 39/757 (5%)
Query: 130 ASEAADQPLKIIWGTNVSIQECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVN 189
ASE + +IWGT+V++ C +F+ FL F KE ++ I I E Y+
Sbjct: 141 ASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPL-----YMQ 195
Query: 190 QLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNG 249
+L ++ +G LN++ ++ ++ + L+ Q++ YPQE+I D V + D+
Sbjct: 196 RLGEINVIGEPFLNVNCEHIKSFD--KNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSI 253
Query: 250 LESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFK 309
LE + +VRP+N K MR LNP DID+L++I G+V+R++ +IP+M AFF+
Sbjct: 254 LEHQI--------QVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQ 305
Query: 310 CNVCNHTVEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPD 369
C VC HT VE+DRG I EP C R C++ +SM L+HNR F D+Q+IKLQE+P+ +P
Sbjct: 306 CQVCAHTTRVEMDRGRIAEPSVCGR--CHTTHSMALIHNRSLFSDKQMIKLQESPEDMPA 363
Query: 370 GQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQK 429
GQTPH+V L +++LVD + GDR+ V+GI+R++PIR NP+ +KS+YKT+IDV+H +K
Sbjct: 364 GQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRK 423
Query: 430 VAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSI 489
R+ + +D E + S + + +KE +R+ D+Y+ L+ ++APSI
Sbjct: 424 TDAKRL-------------HGLDEEAEQKLFSEKRVELLKELSRKPDIYERLASALAPSI 470
Query: 490 YELDDVKKGILLQLFGGANKTFKKGGR--YRGDINILLCGDPSTSKSQILQYVHKIAPRG 547
YE +D+KKGILLQLFGG K F GR +R +INILLCGDP TSKSQ+LQYV+ + PRG
Sbjct: 471 YEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRG 530
Query: 548 VYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEV 607
YTSGKGSSAVGLTAYV +D +T+QLVL++GALVLSD G+CCIDEFDKMN++TRSVLHEV
Sbjct: 531 QYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEV 590
Query: 608 MEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLV 667
MEQQT+SIAKAGII LNARTS+LA+ANPI S++NP ENI LP LLSRFDL++L+
Sbjct: 591 MEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLL 650
Query: 668 LDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKT 727
LD +EA DR LA HL +LY + + ++ ++L + L YI YA I P ++E A
Sbjct: 651 LDPQDEAYDRRLAHHLVALYYQS--EEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQ 708
Query: 728 ELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRL 787
L+ AYV MRK+G S ++A RQLES+IRL+EAHAK+RLS +VE DVEEA RL
Sbjct: 709 ALIEAYVDMRKIG----SSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRL 764
Query: 788 IKSAIKDYATDPKTGKIDMNLVQTGKSVVQRKLLEDLAREILK-ILTERTTDTISFNELS 846
+ A+K ATDP+TG +D++++ TG S RK E+LA + K IL++ T + + +L
Sbjct: 765 HREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILSKGKTPALKYQQLF 824
Query: 847 KLINEQSQDKVESIELSNALTRLQQEDKVVILGEGLR 883
+ I QS + AL L +D + + G+ +R
Sbjct: 825 EDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTVR 861
>At2g16440 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 720
Score = 648 bits (1672), Expect = 0.0
Identities = 338/698 (48%), Positives = 486/698 (69%), Gaps = 35/698 (5%)
Query: 141 IWGTNVSIQECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTS 200
+WGTN+S+Q+ ++ F+ F+ + R+ DD +F +E Y+ + ++ ++
Sbjct: 26 VWGTNISVQDVKSAIEMFVKHFR-EARENSDD--LF------REGKYMVSIRKVIEIEGE 76
Query: 201 NLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESK 260
+++D ++ Y L+++++ YP E++AI D + D + S +N + K
Sbjct: 77 WIDVDAFDVFDYD--PDLYNKMVRYPLEVLAIFDIVLMDIV----------STINRLFEK 124
Query: 261 LFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVE-V 319
+VR +N+ T MR LNP+DI+K++S+KG+++RS+ IIP++ A F+C VC + + +
Sbjct: 125 HVQVRIFNLRTSTSMRNLNPSDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDPI 184
Query: 320 EIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLC 379
+DRG I EP C + C + NSM LVHNRC F D+Q+++LQETPD +P+G TPH+VSL
Sbjct: 185 IVDRGKISEPPTCLKQECMTKNSMTLVHNRCRFADKQIVRLQETPDEIPEGGTPHTVSLL 244
Query: 380 VYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDT 439
++D+LVD+ + GDRIEV+GI+R++ +R P R +KS++KTYID +HI+K +K R+ +
Sbjct: 245 LHDKLVDNGKPGDRIEVTGIYRAMTVRVGPAHRTVKSVFKTYIDCLHIKKASKLRMSAE- 303
Query: 440 STVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGI 499
+ + N + V+E D+R+ +E +++ D+Y+ LSRS+AP+I+ELDDVKKG+
Sbjct: 304 ---DPMDVDNSLRRVDE-------DLRKFQELSKQPDIYERLSRSLAPNIWELDDVKKGL 353
Query: 500 LLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVG 559
L QLFGG G +RGDINILL GDP TSKSQ+LQY+HK++PRG+YTSG+GSSAVG
Sbjct: 354 LCQLFGGNALNLASGANFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVG 413
Query: 560 LTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAG 619
LTAYV +D +T + VLESGALVLSD G+CCIDEFDKM+D+ RS+LHEVMEQQT+SIAKAG
Sbjct: 414 LTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAG 473
Query: 620 IITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDREL 679
II +LNARTS+LA ANP SRYNP L V ENI LPP LLSRFDL+YL+LDK +E +DR L
Sbjct: 474 IIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYLILDKPDEQTDRRL 533
Query: 680 AKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKM 739
AKH+ +L+ E+ +Q + + + LT Y++YA++NIHP +++ A EL R YV +RK
Sbjct: 534 AKHIVALHFENAES--AQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGYVELRKA 591
Query: 740 GDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDP 799
G + S +K ITAT RQ+ES+IRLSEA A+MR SE VE DV+EA RL++ A++ ATD
Sbjct: 592 GKFAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATDH 651
Query: 800 KTGKIDMNLVQTGKSVVQRKLLEDLAREILKILTERTT 837
TG IDM+L+ TG S +R + A I I E+ T
Sbjct: 652 ATGTIDMDLINTGVSASERMRRDTFASSIRDIALEKIT 689
>7304207 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 866
Score = 629 bits (1623), Expect = e-180
Identities = 342/759 (45%), Positives = 488/759 (64%), Gaps = 39/759 (5%)
Query: 129 PASEAADQPLKIIWGTNVSIQECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYV 188
P SE++ P ++WGTNV + +C + F+ F+M F + EI N +Q LY +
Sbjct: 142 PVSESSQAPQLVVWGTNVVVSQCKSKFKSFIMRF---IDPSAEQDEISENIDVNQPLY-L 197
Query: 189 NQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDN 248
+L ++ L LNL+ +L + + L+ Q++ YPQE+I D + +
Sbjct: 198 QKLEEIHTLEEPYLNLNCAHLKTFD--QDLYRQLICYPQEVIPGFDMAINEMF------- 248
Query: 249 GLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFF 308
E Y + +VRP+N + + MR LNP D+D+L+SI G+V+RS+ +IP+M AFF
Sbjct: 249 -FERYPAALLEHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFF 307
Query: 309 KCNVCNHTVEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVP 368
CN+C+ + VE+DRG I +P C CN+ + L+HNR F D+Q++KLQE+PD +
Sbjct: 308 SCNICSFSTTVEVDRGRINQPTLCTN--CNTNHCFRLIHNRSEFTDKQLVKLQESPDDMA 365
Query: 369 DGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQ 428
GQTPH+V L +++LVD + GDR+ V+GI+R+ P+++ ++KS+YKT++DVVH +
Sbjct: 366 AGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVKSVYKTHVDVVHFR 425
Query: 429 KVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPS 488
KV R+ D + E + ++ A++ D+YD L+R+IAPS
Sbjct: 426 KVDNKRLYEDEEGKDH--------------IFPPERVELLQLLAKKPDIYDRLARAIAPS 471
Query: 489 IYELDDVKKGILLQLFGGANKTFKKGGR--YRGDINILLCGDPSTSKSQILQYVHKIAPR 546
IYE DD+KKGILLQLFGG K GR +R +I++LLCGDP TSKSQ+LQYV + PR
Sbjct: 472 IYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPR 531
Query: 547 GVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHE 606
YTSG+GSSAVGLTAYVT+D +T+QLVL++GALVL+D GVCCIDEFDKMND+TRSVLHE
Sbjct: 532 SQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHE 591
Query: 607 VMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYL 666
VMEQQT+SIAKAGII LNARTSILA+ANP S++N + +N+ LP LLSRFDL++L
Sbjct: 592 VMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFL 651
Query: 667 VLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAK 726
VLD +E D+ LA HL SLY R + + + + L YI YA++++ P +++ A+
Sbjct: 652 VLDPQDEIFDKRLASHLVSLYYVTRHE--EEDTMFDMSVLRDYIAYAREHLSPTLSDEAQ 709
Query: 727 TELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVR 786
L++AYV MRK+G + +I+A RQLES+IRLSEAHAK+RLS +VEL DVEEA R
Sbjct: 710 QRLIQAYVDMRKVG----AGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWR 765
Query: 787 LIKSAIKDYATDPKTGKIDMNLVQTGKSVVQRKLLEDLAREILKILTER-TTDTISFNEL 845
L + A+K ATDP +GKID+ ++ TG S RK DL I + L ++ T+ + +L
Sbjct: 766 LHREALKQSATDPLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKKGKVLTVPYQKL 825
Query: 846 SKLINEQSQDKVESIELSNALTRLQQEDKVVILGEGLRR 884
I E SQ + + +AL +Q E +V++G+ R
Sbjct: 826 FSDIKEGSQIMITREQFEDALKEVQDEGAIVVMGKNTIR 864
>CE21767 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 823
Score = 607 bits (1566), Expect = e-173
Identities = 339/758 (44%), Positives = 486/758 (63%), Gaps = 58/758 (7%)
Query: 136 QPLKIIWGTNVSIQECGNSFREFLMSFKLKYRKE----LDDQEIFINETTDQELYYVNQL 191
QP +WGT + + + SFR+FL +FK+ E + + ++E YY+ +L
Sbjct: 102 QPRLYVWGTRICVADVQRSFRDFLTTFKISQLAEDENMMTGHDEALHEIDVNHPYYMERL 161
Query: 192 NQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLE 251
+ +++NL++++L A+ +E L+ +++ YP ++I +D V +
Sbjct: 162 LECNDAEVTHINLNLKHLNAF--SEALYRKVIAYPADVIPYLDIVVNEVFAER------- 212
Query: 252 SYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCN 311
N ++ ++RP+N + + MR LNPND+D+L++I G+V R++ +IP+M +F+C
Sbjct: 213 --FNRTLAQSIELRPFNAQKTRNMRGLNPNDVDQLITISGMVTRTSSLIPEMRSGYFQCA 270
Query: 312 VCNHTVEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQ 371
VC +E E+D+G I+EPV C C++ + LVHNR F D+QV+KLQE+PD +P G+
Sbjct: 271 VCAFGIESEVDKGRIEEPVVCTN--CSNTHCFQLVHNRSVFLDKQVVKLQESPDDMPSGE 328
Query: 372 TPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVA 431
TPH+VS+ + LV+S + GDRI V+GIFR+ ++ NPKQRAL S+Y+T ID +H +K+
Sbjct: 329 TPHTVSVYAHGSLVESVQPGDRITVTGIFRATGMKVNPKQRALASVYRTSIDALHFRKM- 387
Query: 432 KDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYE 491
DTS + Q DN E T++ E I++I E ++R D+ D L++SIAPSIYE
Sbjct: 388 ------DTSRLHQ-------DNGE---TITEERIQQIIELSKRPDIMDALAQSIAPSIYE 431
Query: 492 LDDVKKGILLQLFGGANKTFKKGGR--YRGDINILLCGDPSTSKSQILQYVHKIAPRGVY 549
DDVK+G+L LFGG K + + R +INILLCGDP TSKSQ+LQYV+++ PR Y
Sbjct: 432 HDDVKRGLLCLLFGGTRKDDETTNKTKLRSEINILLCGDPGTSKSQMLQYVYRLLPRSQY 491
Query: 550 TSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVME 609
TSGKGSSAVGLTA V+RD DTKQLVL++GALVL+D GVCCIDEFDKMN++ RSVLHEVME
Sbjct: 492 TSGKGSSAVGLTASVSRDADTKQLVLQTGALVLADNGVCCIDEFDKMNESARSVLHEVME 551
Query: 610 QQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLD 669
QQT+SIAKAGII LNAR S+LA+ANP++S++N N + ENI LP LLSRFDL++L++D
Sbjct: 552 QQTLSIAKAGIICQLNARASVLAAANPVDSKWNRNKTIVENITLPHTLLSRFDLIFLIVD 611
Query: 670 KVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTEL 729
+E DR L HL SLY E+ + + + + + L YI YAK NIHP ++E A +
Sbjct: 612 AQDEMQDRRLGNHLVSLYFEN-DGNQEKTEHVDMNLLRDYIAYAKANIHPKLSEEASQFI 670
Query: 730 VRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIK 789
+ Y+ MRK G + +ITA RQLES+IRLSEAHAK+RLS+ V ++DVE+A L +
Sbjct: 671 IEKYLFMRKAG----AQHGQITAYPRQLESLIRLSEAHAKIRLSQEVSVDDVEKAFTLWR 726
Query: 790 SAIKDYATDPKTGKIDMNLVQTGKSVVQRKLLEDLAREILKIL--------------TER 835
A+K A DP TG++D+ ++ +G S RK +E + +LK L T +
Sbjct: 727 EALKQSAVDPSTGRVDVAILASGMSASGRKAVEAMCEAVLKQLKTAKGFVTSKALFHTLK 786
Query: 836 TTDTISFNEL-SKLINEQSQDKVESIELSNALTRLQQE 872
+ D E+ + INE S K ESI S R Q E
Sbjct: 787 SADKTCQREVFDEAINELS--KKESIARSGDRIRFQTE 822
>ECU02g1150 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 708
Score = 546 bits (1408), Expect = e-155
Identities = 307/746 (41%), Positives = 455/746 (60%), Gaps = 90/746 (12%)
Query: 138 LKIIWGTNVSIQECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQL 197
+K+IWGT ++IQE F+EF+ R+ D I QE + L
Sbjct: 43 VKVIWGTTINIQETAERFKEFV-------RRNRDYHTILEQMDLTQEFVF--------DL 87
Query: 198 GTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEI 257
+L+ D+++ LA YPQE++ I +++ E Y+
Sbjct: 88 HCDDLDADLKSQLAM------------YPQEVLPIFQGSLQ------------EIYMENF 123
Query: 258 ES--KLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNH 315
S L ++RP+ + +R ++PNDIDK+V I G+V+RS+ +IP++ AFF+C+ C H
Sbjct: 124 PSFGGLIRIRPFGIGRPLSIRNIDPNDIDKIVQISGMVIRSSSVIPEIVRAFFRCSRCGH 183
Query: 316 TVEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHS 375
VE R +I EP +C C + LVHN F+D+QV+++QE P+ +P+G TP +
Sbjct: 184 ECLVESVRNVIDEPNKCE---CGGKYTQQLVHNASEFEDKQVVRIQELPEGIPNGTTPMA 240
Query: 376 VSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRV 435
+++ +E VD GDR++++G+ ++ P+R NP R +KS ++ Y+D++
Sbjct: 241 MTIVCRNEFVDGLVPGDRVKLTGVLKATPVRLNPVMRKIKSTFRIYLDLL---------- 290
Query: 436 GVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDV 495
Q++ +I+ SS+ I +I E +R DVY++L+ S+APS+ ++D
Sbjct: 291 -------SYQVINRKIE--------SSDPIDKIDELRKRPDVYEILANSVAPSVCGMEDT 335
Query: 496 KKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGS 555
KK ++LQLFGG K R RGDINILL GDP SKSQ+L ++H+ + RG+YTSG+GS
Sbjct: 336 KKALVLQLFGGVRKELGSS-RLRGDINILLAGDPGISKSQLLSFIHRTSERGMYTSGRGS 394
Query: 556 SAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISI 615
SAVGLTA V +D DT Q +LESGALVLSD G+CCIDEFDKM+D+TRSVLHEVMEQQT+S+
Sbjct: 395 SAVGLTASVAKDPDTGQFILESGALVLSDNGICCIDEFDKMSDSTRSVLHEVMEQQTVSV 454
Query: 616 AKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEAS 675
AKAGIITTLNAR SILAS NPI S+YNP + ENI+LPP LLSRFD+V L++D+ +E
Sbjct: 455 AKAGIITTLNARCSILASCNPIESKYNPRKSIVENINLPPTLLSRFDVVCLMIDRCDEFY 514
Query: 676 DRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVG 735
DR + H+ SLY E+ + + + + L AY+ A++ I P +T + L ++YV
Sbjct: 515 DRTIGDHIVSLYSEE----TQRKEYIDADLLKAYVREARR-IVPRLTPESMKMLTQSYVD 569
Query: 736 MRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDY 795
+R+M + K ITATTRQLES+IRLSEAHA+MR S VE +DV EAVR+I+ ++ Y
Sbjct: 570 LRQM-----DNGKTITATTRQLESLIRLSEAHARMRFSNAVEAKDVREAVRIIRESLLMY 624
Query: 796 ATDPKTGKIDMNLVQTGKSVVQRKLLEDLAREILKILTERTTDTISFNELSKLINEQSQD 855
A DP TGK+DM+++ TG+S + ++LE+L IL ++ + E+S ++ +
Sbjct: 625 AIDPSTGKVDMDMIITGRSTFKNRMLENLKDAILLMVKGKA-------EVSDVVKNTGAE 677
Query: 856 KVESIELSNALTRLQQEDKVVILGEG 881
+ +E AL L E K++ +G
Sbjct: 678 EKMVLE---ALEELVLEGKMIASVQG 700
>SPCC16A11.17 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 546
Score = 497 bits (1280), Expect = e-140
Identities = 240/402 (59%), Positives = 308/402 (75%), Gaps = 4/402 (0%)
Query: 129 PASEAADQPLKIIWGTNVSIQECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYV 188
P+SE AD +++IWGTNVSIQE SFR FL FK KYR E ++ + ++L Y+
Sbjct: 147 PSSEVADDTVRVIWGTNVSIQESIASFRGFLRGFKKKYRPEYRNE--LMPPPDAEQLVYI 204
Query: 189 NQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDN 248
L MR +G LNLD+++L Y T+KL+HQ+ YPQEII IMDQT+KD M+ L N
Sbjct: 205 EALRNMRIMGLEILNLDVQDLKHYPPTKKLYHQLYSYPQEIIPIMDQTIKDVMLDLLGTN 264
Query: 249 GLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFF 308
E LN+IE K++K+RP+N+E MR+LNP DIDKL+SIKGLVLR TP+IPDM AFF
Sbjct: 265 PPEDVLNDIELKIYKIRPFNLEKCINMRDLNPGDIDKLISIKGLVLRCTPVIPDMKQAFF 324
Query: 309 KCNVCNHTVEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVP 368
+C+VC H V VEIDRG I EP++CPR VC + N+M L+HNR F D+QVIKLQETPD+VP
Sbjct: 325 RCSVCGHCVTVEIDRGRIAEPIKCPREVCGATNAMQLIHNRSEFADKQVIKLQETPDVVP 384
Query: 369 DGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQ 428
DGQTPHSVSLCVYDELVDS RAGDRIEV+GIFR +P+R NP+ R +KSL+KTY+DVVHI+
Sbjct: 385 DGQTPHSVSLCVYDELVDSARAGDRIEVTGIFRCVPVRLNPRMRTVKSLFKTYVDVVHIK 444
Query: 429 KVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPS 488
K K R+G D ST+E + ++ ++E+R +S E++ +I++ ++R D+YD+LSRS+APS
Sbjct: 445 KQDKRRLGTDPSTLESDIAEDAALQIDEVRKISDEEVEKIQQVSKRDDIYDILSRSLAPS 504
Query: 489 IYELDDVKKGILLQLFGGANKTFKKGG--RYRGDINILLCGD 528
IYE+DDVKKG+LLQLFGG NK+F KG RYRGDINIL+CGD
Sbjct: 505 IYEMDDVKKGLLLQLFGGTNKSFHKGASPRYRGDINILMCGD 546
>SPBC25D12.03c [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 760
Score = 368 bits (944), Expect = e-101
Identities = 235/686 (34%), Positives = 379/686 (54%), Gaps = 67/686 (9%)
Query: 149 QECGNSFREFLMSFKLKYRKE-LDDQEIFINETTDQELY---YVNQLNQMRQLGTSNLNL 204
+EC + +FL FK + ++ +Q+I +++ D+ Y++ L ++ ++ +N+
Sbjct: 14 EECQHKITDFLSHFKQEQVQDGQQNQDISMSDAGDEPFLKSKYMDILQKISNRESNVINV 73
Query: 205 DIRNLLAYKHTE-KLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFK 263
D+ +L + ++ +L H I + + + Q M ++ +Y NE+ + +
Sbjct: 74 DLNDLYEFDPSDTQLLHNIESNAKRFVELFSQCADALMPPPTVEI---NYRNEVLDVIMQ 130
Query: 264 VRPYNVET--------------------------KK--GMRELNPNDIDKLVSIKGLVLR 295
R E KK +R+L ++ L++++G+V R
Sbjct: 131 QRVQRNENIDPEHKGFPPELTRGYDLYFRPVTRNKKPFSVRDLRGENLGSLLTVRGIVTR 190
Query: 296 STPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVC--NSPNSMVLVHNRCT-F 352
++ + P ++V + C+ C + V EI + CP C N + + R + F
Sbjct: 191 TSDVKPSLTVNAYTCDRCGYEVFQEIRQKTFLPMSECPSDECKKNDAKGQLFMSTRASKF 250
Query: 353 QDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQR 412
Q +K+QE + VP G P S+++ +Y + S GD +++SGIF P R
Sbjct: 251 LPFQEVKIQELTNQVPIGHIPRSLTVHLYGAITRSVNPGDIVDISGIFLPTPYTGFRAMR 310
Query: 413 ALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETA 472
A L TY++ ++ ++ K+ ++ +T SE I E
Sbjct: 311 A-GLLTDTYLECHYVSQIIKNYTNIE-------------------KTPQSE--AAIAELN 348
Query: 473 RRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTS 532
+ +VY+ L++SIAP IY +DVKK +LL L GG K G R RGDINI L GDP +
Sbjct: 349 QGGNVYEKLAKSIAPEIYGHEDVKKALLLLLVGGVTKELGDGMRIRGDINICLTGDPGVA 408
Query: 533 KSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDE 592
KSQ+L+Y+ K+APRGVYT+G+GSS VGLTA V RD T ++VLE GALVL+D G+CCIDE
Sbjct: 409 KSQLLKYISKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDE 468
Query: 593 FDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENID 652
FDKM+++ R+ +HEVMEQQTISI+KAGI TTLNARTSILA+ANP+ RYNP + NI+
Sbjct: 469 FDKMDESDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYNPKVAPIHNIN 528
Query: 653 LPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINY 712
LP LLSRFD+++L+LD + +D LA+H+T +++ + + + P + YI+
Sbjct: 529 LPAALLSRFDILFLILDTPSRETDEHLAQHVTYVHMHNEQPKMDFEPLDP-NMIRHYISS 587
Query: 713 AKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATT-RQLESMIRLSEAHAKMR 771
A+Q PV+ + + AYV +R+ ++E++ TT R L +++R+ +A A++R
Sbjct: 588 ARQ-YRPVVPKDVCDYVTGAYVQLRQNQKRDEANERQFAHTTPRTLLAILRMGQALARLR 646
Query: 772 LSERVELEDVEEAVRLI---KSAIKD 794
S RVE+ DV+EA+RL+ KS++ D
Sbjct: 647 FSNRVEIGDVDEALRLMSVSKSSLYD 672
>SPBC211.04c [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 892
Score = 362 bits (930), Expect = 1e-99
Identities = 242/705 (34%), Positives = 373/705 (52%), Gaps = 60/705 (8%)
Query: 128 RPASEAADQPLKIIWGTNVSIQECGNSFREFLMSFKLKYRKELDDQEIFINE---TTDQE 184
+P + + K+I T S++E +F EFL+SF D + + + QE
Sbjct: 52 KPFAAIGEAIPKVIDTTGESVRE---AFEEFLLSFS--------DDRVAGGDALPSASQE 100
Query: 185 LYYVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKL--FHQILYYPQEIIAIMDQTVKDC-- 240
YYV Q++ + + +D ++L +Y L Q + ++ + + ++
Sbjct: 101 KYYVQQIHGLAMYEIHTVYVDYKHLTSYNDVLALAIVEQYYRFSPFLLRALQKLIEKFEP 160
Query: 241 ---MVSLALDNGLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRST 297
SL+ +N S + K F + YN+ + +R+L + I +L +I G V R++
Sbjct: 161 EYYRSSLSRENASLSPNFKASDKTFALAFYNLPFRSTIRDLRTDRIGRLTTITGTVTRTS 220
Query: 298 PIIPDMSVAFFKCNVCNHTVEVEIDRGI-IQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQ 356
+ P+++ F C C HTV +++ EP +CP +C + S L ++ +FQD Q
Sbjct: 221 EVRPELAQGTFICEEC-HTVVSNVEQAFRYTEPTQCPNELCANKRSWRLNISQSSFQDWQ 279
Query: 357 VIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPI----------- 405
+++QE + +P G P ++ + + ++V+ +AGD+ +GI ++P
Sbjct: 280 KVRIQENSNEIPTGSMPRTLDVILRGDIVERAKAGDKCAFTGILIAVPDVSQLGIPGVKP 339
Query: 406 -----------RSNPKQRALKSL------YKTYIDVVHIQKV-AKDRVGVDTSTVEQQLL 447
R LKSL YK +Q A D+ G D Q +
Sbjct: 340 EAYRDSRNFGGRDADGVTGLKSLGVRDLTYKLSFLACMVQPDDANDKSGADVRGDGSQGI 399
Query: 448 QNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGA 507
+ Q E +++LS E+I ++ +Y L+ S+APS+Y + +KKGILLQL GG
Sbjct: 400 EEQD---EFLQSLSQEEIDDLRAMVHSDHIYSRLTNSLAPSVYGHEIIKKGILLQLMGGV 456
Query: 508 NKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRD 567
+K +G RGD+NI + GDPSTSKSQ L+YV PR +YTSGK SSA GLTA V +D
Sbjct: 457 HKLTPEGINLRGDLNICIVGDPSTSKSQFLKYVCNFLPRAIYTSGKASSAAGLTAAVVKD 516
Query: 568 VDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNAR 627
+T +E+GAL+L+D G+C IDEFDKM+ + + +HE MEQQTISIAKAGI TLNAR
Sbjct: 517 EETGDFTIEAGALMLADNGICAIDEFDKMDLSDQVAIHEAMEQQTISIAKAGIQATLNAR 576
Query: 628 TSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLY 687
TSILA+ANPI RYN + NI++ P++SRFDL ++VLD+ NE+ DR LAKH+ ++
Sbjct: 577 TSILAAANPIGGRYNRKTTLRNNINMSAPIMSRFDLFFVVLDECNESVDRHLAKHIVDIH 636
Query: 688 LEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDE 747
R D++ E L YI YA+ P + + E+V+ Y +R M D + +
Sbjct: 637 -RLRDDAMQPE--FSTEQLQRYIRYAR-TFKPKLNTESCAEIVKKYKQLR-MDDAQGAGK 691
Query: 748 KRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAI 792
T RQLESMIRLSEA A+ + + V EA L++ +I
Sbjct: 692 NSYRITVRQLESMIRLSEAIARANCVDDITPAFVNEAYSLLRQSI 736
>CE09874 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 730
Score = 350 bits (898), Expect = 6e-96
Identities = 206/537 (38%), Positives = 313/537 (57%), Gaps = 36/537 (6%)
Query: 275 MRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPR 334
+R + +I LVS+KG+V+R+T + P + V + C+ C V + PV CP
Sbjct: 162 VRNIKATEIGHLVSMKGVVIRATEVKPCVEVMTYTCDTCAAEVYQPVKGMQFTPPVNCPN 221
Query: 335 VVCNSPNSMVLVHNRCT---FQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAG 391
C + +H + F Q +K+QE + VP G P ++++ VY E+ C G
Sbjct: 222 KECVEAKANGRLHMQLRGSKFVKFQELKIQELSEQVPVGSIPRTMTVHVYGEMTRKCNTG 281
Query: 392 DRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQI 451
+ + VSG+F +PI + + + TY++ + I
Sbjct: 282 NVVHVSGVF--LPIMQSGFRPTGGLVADTYLEA------------------------HYI 315
Query: 452 DNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTF 511
+N+++ T + ++ R+ D Y+ L+ SIAP I+ DVKK +L+ L GG N
Sbjct: 316 NNLDDNPTFNGVQSAELEVLRRKGDNYETLAASIAPEIFGHVDVKKCLLMALVGG-NDNS 374
Query: 512 KKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTK 571
G + RG IN+L+ GDP +KSQ+L YV+++APR YT+G+GSS VGLTA V +D T
Sbjct: 375 SNGMKIRGCINVLMMGDPGVAKSQLLGYVNRLAPRSQYTTGRGSSGVGLTAAVMKDPVTG 434
Query: 572 QLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSIL 631
++ LE GALVL+DGG+CCIDEFDKM D+ R+ +HEVMEQQTISIAKAGI+TTLNART+I+
Sbjct: 435 EMSLEGGALVLADGGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAGIMTTLNARTAII 494
Query: 632 ASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDR 691
A+ANP RYNPN + +N+DLP LLSRFDL+ L+ DK + +D+ LA+H+T ++
Sbjct: 495 AAANPAYGRYNPNRSIEQNVDLPAALLSRFDLILLMQDKADRENDKILAEHITYVHQHGC 554
Query: 692 PDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRIT 751
+ + D++ +E L YI+ K P + + + +V AYV MR+ D+R
Sbjct: 555 HPNREKKDLISLETLREYISLCK-TYTPTVDPALRERIVEAYVEMRR---DARYSSDPTF 610
Query: 752 ATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDMNL 808
+ R + ++R++ A AK+RLS V+ DVEEA+RL++ A KD + P+ KI+ +
Sbjct: 611 VSPRMILGIVRMATARAKLRLSTIVDESDVEEALRLMQFA-KD-SLRPEQNKIEKRM 665
>At4g02060 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 716
Score = 350 bits (897), Expect = 7e-96
Identities = 213/538 (39%), Positives = 314/538 (57%), Gaps = 36/538 (6%)
Query: 275 MRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPR 334
+RE+ + I +LV I G+V R + + P M+VA + C C H + E+ + +CP
Sbjct: 143 IREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPS 202
Query: 335 VVC---NSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAG 391
C + + +L F Q K+QE + VP G P S+++ + EL G
Sbjct: 203 SRCRLNSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPG 262
Query: 392 DRIEVSGIFRSIPIRSNPKQRA--LKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQN 449
D +E SGIF IP RA + Y V H +K ++ +
Sbjct: 263 DVVEFSGIFLPIPYTGFKALRAGLVADTYLEATSVTHFKKKYEE-------------YEF 309
Query: 450 QIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANK 509
Q D E+I L+ + D+Y+ LSRS+AP IY +D+KK +LL L G ++
Sbjct: 310 QKDEEEQIARLAED-----------GDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHR 358
Query: 510 TFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVD 569
K G + RGD++I L GDP +KSQ+L+++ +APRGVYT+GKGSS VGLTA V RD
Sbjct: 359 QLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQV 418
Query: 570 TKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTS 629
T ++VLE GALVL+D G+C IDEFDKM+++ R+ +HEVMEQQT+SIAKAGI T+LNART+
Sbjct: 419 TNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTA 478
Query: 630 ILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLE 689
+LA+ANP RY+ ENI+LPP LLSRFDL++L+LD+ + SD ELAKH+ L++
Sbjct: 479 VLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHV--LHVH 536
Query: 690 DRPDSVSQG-DILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEK 748
+S + G + L L AYI+ A++ + P + + + AY +R+ ++++S+
Sbjct: 537 QTEESPALGFEPLEPNILRAYISAARR-LSPYVPAELEEYIATAYSSIRQ--EEAKSNTP 593
Query: 749 RITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIK-SAIKDYATDPKTGKID 805
T R L S++R+S A A++R SE V DV+EA+RL++ S I YA D + +D
Sbjct: 594 HSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMSKISLYADDRQKAGLD 651
>CE19038 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 881
Score = 348 bits (893), Expect = 2e-95
Identities = 232/703 (33%), Positives = 360/703 (51%), Gaps = 74/703 (10%)
Query: 149 QECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRN 208
+E F+ FL SF +E +++ Y+ + M +L + +
Sbjct: 166 KEIERRFKNFLRSF---------------HEPGNKQTKYIQMIKSMAADNRESLEVSFTD 210
Query: 209 LLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYN 268
L + + + + P E++AIMD+ + ++++ NEI KVR
Sbjct: 211 LSDDNGEQNISYFLPEAPNEMLAIMDRAATEVVMNMY--PFYSRVCNEI-----KVRISQ 263
Query: 269 VETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQ- 327
+ ++ +R L ++ L+ G+V ++ I+P ++V + C C + + + + +
Sbjct: 264 LPVEEDIRMLRQVHLNMLIRTAGVVTIASGILPQLAVVKYDCVACGYLLGPFVQQNDEEV 323
Query: 328 EPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDS 387
P CP C L + + Q I +QE+P+ V G+ P S + + +L DS
Sbjct: 324 RPTICPS--CQGKGPFELNVENTVYHNYQRITMQESPNKVAAGRLPRSKDVILLGDLCDS 381
Query: 388 CRAGDRIEVSGIF-RSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQL 446
C+ GD IEV+G++ + N KQ ++ T I HI KD++ D
Sbjct: 382 CKPGDEIEVTGVYTNNFDGSLNYKQGF--PVFNTLIHANHITN--KDKMASDQ------- 430
Query: 447 LQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGG 506
L+ EDI+ I+E ++ ++ + SIAPSIY DDVK+ I L LF G
Sbjct: 431 -------------LTDEDIKAIRELSQDPNISQRVFSSIAPSIYGHDDVKRAIALALFRG 477
Query: 507 ANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTR 566
K R RGDIN+LLCGDP T+KSQ L+Y IAPR V T+G+G+SAVGLTAYV R
Sbjct: 478 EAKNPGAKHRLRGDINVLLCGDPGTAKSQFLRYAAHIAPRSVLTTGQGASAVGLTAYVQR 537
Query: 567 DVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNA 626
T++ LE+GA+VL+D GVC IDEFDKM+D R+ +HE MEQQ+ISI+KAGI+T+L+A
Sbjct: 538 HPVTREWTLEAGAMVLADKGVCLIDEFDKMSDQDRTSIHEAMEQQSISISKAGIVTSLHA 597
Query: 627 RTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSL 686
R +++A++NPI RYNP EN+DL P+LSRFD++ ++ D V+ D LAK +
Sbjct: 598 RCTVIAASNPIGGRYNPTRTFAENVDLTEPILSRFDVLCVIRDSVDSVEDERLAKFVVGN 657
Query: 687 YLEDRPDS---VSQGD--------------ILPVEFLTAYINYAKQNIHPVITESAKTEL 729
+ PD+ V +GD ++P + L YI YA++ HP + E +
Sbjct: 658 HRTHHPDAKKIVKEGDELEEDQMDERTGVRLIPQDLLRKYIIYAREKCHPTLPEQHSEKF 717
Query: 730 VRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIK 789
+ MRK + S + T R +ESMIRLSEAHAK+ L V ED A+R++
Sbjct: 718 SNIFAQMRKESMATGS----VAITVRHVESMIRLSEAHAKLHLRSYVNDEDCAAAIRVM- 772
Query: 790 SAIKDYATDPKTGKIDMNLVQTGKSVVQRKLLEDLAREILKIL 832
++ + K + M + + + + +L ILK L
Sbjct: 773 --LESFVNTQKASIMRMMKKTFSRHLTENRSANELLLFILKQL 813
>YGL201c [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 1017
Score = 347 bits (890), Expect = 5e-95
Identities = 216/586 (36%), Positives = 323/586 (54%), Gaps = 56/586 (9%)
Query: 256 EIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNH 315
E ++F++ +N+ T +R++ I L+SI G V R++ + P++ A F C++C
Sbjct: 257 EQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTCDMCRA 316
Query: 316 TVEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHS 375
V+ EP CP C + L R F D Q +++QE + +P G P +
Sbjct: 317 IVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTGSMPRT 376
Query: 376 VSLCVYDELVDSCRAGDRIEVSGIFRSIPIRS-------------------------NPK 410
+ + + + V+ + GDR + +G+ +P + N
Sbjct: 377 LDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTEGLNSG 436
Query: 411 QRALKSL------YKTYIDVVHIQKVAKDRVGVDTSTV-------EQQLLQN-QIDNVEE 456
L+SL YK H+ + + +G + E Q+ N Q +NV +
Sbjct: 437 VTGLRSLGVRDLTYKISFLACHVISIGSN-IGASSPDANSNNRETELQMAANLQANNVYQ 495
Query: 457 ---------IRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGA 507
+ +LSS++I +KE + +YD L RSIAP+++ + VKKGILLQ+ GG
Sbjct: 496 DNERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQMLGGV 555
Query: 508 NKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRD 567
+K+ +G + RGDINI + GDPSTSKSQ L+YV APR VYTSGK SSA GLTA V RD
Sbjct: 556 HKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAAVVRD 615
Query: 568 VDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNAR 627
+ +E+GAL+L+D G+CCIDEFDKM+ + + +HE MEQQTISIAKAGI TLNAR
Sbjct: 616 EEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNAR 675
Query: 628 TSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLY 687
TSILA+ANP+ RYN L + N+++ P++SRFDL +++LD NE D ELA H+ L+
Sbjct: 676 TSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHIVDLH 735
Query: 688 LEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRS-D 746
++ R +++ E L YI YA+ P++T+ A++ LV Y +RK DD++
Sbjct: 736 MK-RDEAIEPP--FSAEQLRRYIKYAR-TFKPILTKEARSYLVEKYKELRK--DDAQGFS 789
Query: 747 EKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAI 792
T RQLESMIRLSEA A+ + + + EA L++ +I
Sbjct: 790 RSSYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSI 835
>Hs20535929 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 904
Score = 346 bits (887), Expect = 1e-94
Identities = 212/629 (33%), Positives = 342/629 (53%), Gaps = 60/629 (9%)
Query: 187 YVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLAL 246
+ +++ M + +L ++ +L A +H F + P E++ I D+ + V LA+
Sbjct: 215 FKERISDMCKENRESLVVNYEDLAAREHVLAYF--LPEAPAELLQIFDEAALE--VVLAM 270
Query: 247 DNGLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVA 306
+ N I VR ++ + +R L +++L+ G+V T ++P +S+
Sbjct: 271 YPKYDRITNHIH-----VRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMV 325
Query: 307 FFKCNVCNHTVEVEIDRGIIQ-EPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPD 365
+ CN CN + + +P CP C S + +Q+ Q I++QE+P
Sbjct: 326 KYNCNKCNFVLGPFCQSQNQEVKPGSCPE--CQSAGPFEVNMEETIYQNYQRIRIQESPG 383
Query: 366 LVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSL--YKTYID 423
V G+ P S + +LVDSC+ GD IE++GI+ N +L + + +
Sbjct: 384 KVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYH------NNYDGSLNTANGFPVFAT 437
Query: 424 VVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSR 483
V+ VAK DN + L+ ED++ I ++ + + +
Sbjct: 438 VILANHVAKK------------------DNKVAVGELTDEDVKMITSLSKDQQIGEKIFA 479
Query: 484 SIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKI 543
SIAPSIY +D+K+G+ L LFGG K + RGDIN+LLCGDP T+KSQ L+Y+ K+
Sbjct: 480 SIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKV 539
Query: 544 APRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSV 603
+ R ++T+G+G+SAVGLTAYV R +++ LE+GALVL+D GVC IDEFDKMND R+
Sbjct: 540 SSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTS 599
Query: 604 LHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDL 663
+HE MEQQ+ISI+KAGI+T+L AR +++A+ANPI RY+P+L +EN+DL P++SRFD+
Sbjct: 600 IHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDI 659
Query: 664 VYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDI------------------LPVEF 705
+ +V D V+ D LA+ + ++ P + + + LP E
Sbjct: 660 LCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEV 719
Query: 706 LTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSE 765
L YI YAK+ +HP + + + ++ + Y +RK + S I T R +ESMIR++E
Sbjct: 720 LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGS----IPITVRHIESMIRMAE 775
Query: 766 AHAKMRLSERVELEDVEEAVRLIKSAIKD 794
AHA++ L + V +DV A+R++ + D
Sbjct: 776 AHARIHLRDYVIEDDVNMAIRVMLESFID 804
>SPAC3F10.01 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 649
Score = 345 bits (885), Expect = 2e-94
Identities = 222/600 (37%), Positives = 324/600 (54%), Gaps = 43/600 (7%)
Query: 214 HTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVETKK 273
+ E L H +L P +I+ + + V L L E+ I + +R Y+
Sbjct: 3 YNEDLAHLLLSQPTDILPLFESAVTTVAKRL-LYRSQENASTNIPTCQVTLR-YDANILP 60
Query: 274 GMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCP 333
+R L + I KLV + G+++ ++ + + C C T ++I G V+ P
Sbjct: 61 -IRNLTASHISKLVRVPGIIIGASTLSCRATALHLVCRNCRATRILQISGGF--SGVQLP 117
Query: 334 RVVCNSP-----------NSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYD 382
RV C +P + ++ H++ TF D+QV+KLQE PD+VP G+ P + L
Sbjct: 118 RV-CEAPVLDGEKKDCPMDPFIIDHSKSTFIDQQVLKLQEAPDMVPVGELPRHILLNADR 176
Query: 383 ELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTV 442
L + G R ++GIF SI + K ++ YI VV IQ
Sbjct: 177 YLTNQITPGTRCVITGIF-SIFQNKSVKASGAVAIRNPYIRVVGIQ-------------- 221
Query: 443 EQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQ 502
+ D + S E+ E +R ++YD++S SI+P+IY D+KK I
Sbjct: 222 -----MDSNDGSKSTPLFSEEEEEEFLEISRTPNLYDIISNSISPAIYGNVDIKKAIACL 276
Query: 503 LFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTA 562
LF G+ K G R RGDIN+LL GDP T+KSQ L++V ++AP VYTSGKGSSA GLTA
Sbjct: 277 LFSGSKKILPDGMRLRGDINVLLLGDPGTAKSQFLKFVERLAPIAVYTSGKGSSAAGLTA 336
Query: 563 YVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIIT 622
+ RD T++ LE GA+VL+DGG+ CIDEFDKM D R +HE MEQQTISIAKAGI T
Sbjct: 337 SIQRDSVTREFYLEGGAMVLADGGIVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITT 396
Query: 623 TLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKH 682
LN+RTS+LA+ANPI RY+ ENID +LSRFD++++V D+ +E DR +A+H
Sbjct: 397 ILNSRTSVLAAANPIFGRYDDMKTPGENIDFQSTILSRFDMIFIVKDEHDETKDRNIARH 456
Query: 683 LTSLY--LEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMG 740
+ +L+ L++ ++++ G+I P + YINY + P + A +L +V +RK
Sbjct: 457 VINLHTNLQESSETLAIGEI-PFDKFRRYINYCRHKCAPNLDAEAAEKLSSQFVAIRKRV 515
Query: 741 DDSRSD---EKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYAT 797
S D I T RQLE++IR++E+ AKM LS EA+RL ++ AT
Sbjct: 516 HQSEQDSNSRSTIPITVRQLEAIIRITESLAKMSLSPIASEAHATEAIRLFLTSTLAAAT 575
>7299005 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 887
Score = 345 bits (885), Expect = 2e-94
Identities = 216/650 (33%), Positives = 363/650 (55%), Gaps = 64/650 (9%)
Query: 150 ECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNL 209
E N F+ FL +F +D++ + Y +++ +M + S+ + +L
Sbjct: 179 EIANRFQSFLRTF-------VDERGAYT---------YRDRIRRMCEQNMSSFVVSYTDL 222
Query: 210 LAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNV 269
+H F + P +++ I D+ KD ++S+ E EI ++ ++ +
Sbjct: 223 ANKEHVLAYF--LPEAPFQMLEIFDKVAKDMVLSIFPT--YERVTTEIHVRISELPL--I 276
Query: 270 ETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQ-E 328
E + R+L+ N +LV G+V +T ++P +SV + C C + + + + +
Sbjct: 277 EELRTFRKLHLN---QLVRTLGVVTATTGVLPQLSVIKYDCVKCGYVLGPFVQSQNTEIK 333
Query: 329 PVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSC 388
P CP C S + + +++ Q I LQE+P +P G+ P S + + +L D C
Sbjct: 334 PGSCPE--CQSTGPFSINMEQTLYRNYQKITLQESPGRIPAGRIPRSKDVILLADLCDQC 391
Query: 389 RAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQ 448
+ GD +EV+GI+ + S + ++ T I H+ V K
Sbjct: 392 KPGDELEVTGIYTNNYDGSLNTDQGF-PVFATVIIANHV--VVK---------------- 432
Query: 449 NQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGAN 508
D+ + +++L+ EDI I++ ++ + + + S+APSIY D +K+ + L LFGG +
Sbjct: 433 ---DSKQVVQSLTDEDIATIQKLSKDPRIVERVVASMAPSIYGHDYIKRALALALFGGES 489
Query: 509 KTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDV 568
K + + RGDIN+L+CGDP T+KSQ L+Y K+APR V+T+G+G+SAVGLTAYV R+
Sbjct: 490 KNPGEKHKVRGDINLLICGDPGTAKSQFLKYTEKVAPRAVFTTGQGASAVGLTAYVRRNP 549
Query: 569 DTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNART 628
+++ LE+GALVL+D GVC IDEFDKMND R+ +HE MEQQ+ISI+KAGI+T+L AR
Sbjct: 550 VSREWTLEAGALVLADQGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARC 609
Query: 629 SILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYL 688
+++A+ANPI RY+P++ +EN++L P+LSRFD++ +V D+ + D++LAK + ++
Sbjct: 610 TVIAAANPIGGRYDPSMTFSENVNLSEPILSRFDVLCVVKDEFDPMQDQQLAKFVVHSHM 669
Query: 689 EDRPDSVSQGDI----------LPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRK 738
+ P Q ++ +P + L YI YAK+NI P +T + ++ + Y +R+
Sbjct: 670 KHHPSEEEQPELEEPQLKTVDEIPQDLLRQYIVYAKENIRPKLTNIDEDKIAKMYAQLRQ 729
Query: 739 MGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLI 788
+ S + T R +ES+IR+SEAHA+M L E V DV A+R++
Sbjct: 730 ESFATGS----LPITVRHIESVIRMSEAHARMHLRENVMEADVSMAIRMM 775
>YBR202w [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 845
Score = 345 bits (884), Expect = 2e-94
Identities = 223/618 (36%), Positives = 346/618 (55%), Gaps = 57/618 (9%)
Query: 275 MRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPR 334
+R++ + + +L++++G++ R + + P + V + C+ C + V E++ C
Sbjct: 227 VRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTS 286
Query: 335 VVC--NSPNSMVLVHNRCT-FQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAG 391
C N + + R + F Q K+QE VP G P S+++ V LV S G
Sbjct: 287 EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPG 346
Query: 392 DRIEVSGIFRSIPIRSNPKQRALKS--LYKTYIDVVHIQKVAKDRVGVD-TSTVEQQLLQ 448
D ++V+GIF P +ALK+ L +TY++ +++ K TS VE+
Sbjct: 347 DIVDVTGIFLPAPYTGF---KALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEE---- 399
Query: 449 NQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGAN 508
R+ E DVY+ L++SIAP IY DVKK +LL L GG +
Sbjct: 400 ------------------RVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVD 441
Query: 509 KTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDV 568
K G + RGDIN+ L GDP +KSQ+L+ + KI+PRGVYT+GKGSS VGLTA V +D
Sbjct: 442 KRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDP 501
Query: 569 DTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNART 628
T +++LE GALVL+D G+CCIDEFDKM+++ R+ +HEVMEQQTISI+KA I T ART
Sbjct: 502 VTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAVINTNPGART 561
Query: 629 SILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYL 688
SILA+ANP+ R NP L +NI+LP LLSRFD+++L+LD + D +LA+H+T +++
Sbjct: 562 SILAAANPLYGRINPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHM 621
Query: 689 EDRPDSVSQGDILPVE--FLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSD 746
++ + D PVE + YI YAK PV++E+ +V+AY+ +R+ D R
Sbjct: 622 HNKQPDL---DFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQ--DSKREM 675
Query: 747 EKRIT---ATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGK 803
+ + + AT R L +IRLS+A AK+RL++ V+++DVEEA+RL++ + +
Sbjct: 676 DSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESL-------- 727
Query: 804 IDMNLVQTGKSVVQRKLLEDLAREILKILTERTTDTISFNELSKLINEQSQDKVESIELS 863
+T KS + I K+L E +T+S+ + K + + ++LS
Sbjct: 728 ----YQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRG---FTMLQLS 780
Query: 864 NALTRLQQEDKVVILGEG 881
N + + ++ EG
Sbjct: 781 NCIQEYSYLNVWHLINEG 798
>At5g46280 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 776
Score = 342 bits (876), Expect = 2e-93
Identities = 217/646 (33%), Positives = 342/646 (52%), Gaps = 74/646 (11%)
Query: 187 YVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLAL 246
Y+ ++ + L ++I ++ + H ++ +IL P E + + + A+
Sbjct: 23 YMEEIKALVHQKRHRLIINISDI--HHHFREVASRILKNPNEYMQSFCDAATEA--TRAI 78
Query: 247 DNGLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVA 306
D YL E E L Y V REL + I +V ++G+V + + + P + +
Sbjct: 79 D---PKYLKEGELVLVGFEGYFVSRVVTPRELLSDFIGSMVCVEGIVTKCSLVRPKVVKS 135
Query: 307 FFKCNVCNHTV-----EVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQ 361
C ++ G+ V R + N +V + C ++D Q + +Q
Sbjct: 136 VHFCPSTGEFTNRDYRDITSHAGLPTGSVYPTRD--DKGNLLVTEYGLCKYKDHQTLSIQ 193
Query: 362 ETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTY 421
E P+ GQ P SV + D+LVDSC+ GDR+ V GI++++P +S + ++ +++T
Sbjct: 194 EVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALPGKS---KGSVNGVFRTI 250
Query: 422 IDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVL 481
+ +I + K+ + +D+ IK ARR D +D+L
Sbjct: 251 LIANNIALLNKEA---------------------NAPIYTKQDLDNIKNIARRDDAFDLL 289
Query: 482 SRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVH 541
+RS+APSIY +KK ++L + GG K K G RGDIN+++ GDPS +KSQ+L+ +
Sbjct: 290 ARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAIM 349
Query: 542 KIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTR 601
IAP + T+G+GSS VGLTA VT D +T + LE+GA+VL+D G+ CIDEFDKMND R
Sbjct: 350 NIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADKGIVCIDEFDKMNDQDR 409
Query: 602 SVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRF 661
+HEVMEQQT++IAKAGI +LNAR S++A+ANPI Y+ +L T+NI LP LLSRF
Sbjct: 410 VAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGTYDRSLTPTKNIGLPDSLLSRF 469
Query: 662 DLVYLVLDKVNEASDRELAKHLTSL--YLEDRPDSVSQGDI------------------- 700
DL+++VLD+++ D +++H+ + Y DR ++ G +
Sbjct: 470 DLLFIVLDQMDAGIDSMISEHVLRMHRYKNDRGEAGPDGSLPYAREDNAESEMFVKYNQT 529
Query: 701 --------------LPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSD 746
L ++FL YI+YAK I P +T+ A + AY +R G D+++
Sbjct: 530 LHGKKKRGQTHDKTLTIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDTKTG 589
Query: 747 EKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAI 792
+ T R LE++IRL+ AHAKM+LS V D E A++L+ AI
Sbjct: 590 -GTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMNFAI 634
>Hs21359886 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 719
Score = 340 bits (873), Expect = 4e-93
Identities = 207/518 (39%), Positives = 304/518 (57%), Gaps = 31/518 (5%)
Query: 275 MRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPR 334
+RE+ + + KLV+++G+V R + + P M VA + C+ C I + CP
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
Query: 335 VVCNSPNS---MVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAG 391
C + S + L F Q +K+QE D VP G P S+++ V E + G
Sbjct: 209 QECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 268
Query: 392 DRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQI 451
D + V+GIF I +R+ +Q L +TY++ I K+ K
Sbjct: 269 DHVSVTGIFLPI-LRTGFRQVVQGLLSETYLEAHRIVKMNKSE----------------- 310
Query: 452 DNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTF 511
D+ L+ E++R+I E D Y+ L+ SIAP IY +DVKK +LL L GG +++
Sbjct: 311 DDESGAGELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS- 365
Query: 512 KKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTK 571
+G + RG+INI L GDP +KSQ+L Y+ ++APR YT+G+GSS VGLTA V RD +
Sbjct: 366 PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSG 425
Query: 572 QLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSIL 631
+L LE GALVL+D GVCCIDEFDKM + R+ +HEVMEQQTISIAKAGI+TTLNAR SIL
Sbjct: 426 ELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSIL 485
Query: 632 ASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDR 691
A+ANP RYNP + +NI LP LLSRFDL++L+ D+ + +D LA+H+T ++ R
Sbjct: 486 AAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR 545
Query: 692 PDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRIT 751
SQ + L ++ + YI ++ P++ ES + AYV MR+ ++ + +
Sbjct: 546 -QPPSQFEPLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRR---EAWASKDATY 600
Query: 752 ATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIK 789
+ R L +++RLS A A++R+ + VE EDV EA+RL++
Sbjct: 601 TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 638
>At2g07690 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 727
Score = 338 bits (866), Expect = 3e-92
Identities = 226/631 (35%), Positives = 328/631 (51%), Gaps = 51/631 (8%)
Query: 226 PQEIIAIMDQTVKDCMVSLALDNGLES-YLNEIESKLFKVRPYNVETKKGMRELNPNDID 284
P + + + ++ + + L + E + E ++ ++ + E MR L I
Sbjct: 84 PADYLPVFEKAAGEVLTGLKMREANEGGVMEEPLTRDVQILLTSREDPVSMRLLGAQYIS 143
Query: 285 KLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVCNSP---- 340
KLV I G+ + ++ + + F C C T EV G+ V PR N P
Sbjct: 144 KLVKISGISIAASRVKAKATYVFLVCKNCKKTREVPCRPGLGGAIV--PRSCDNIPQPGE 201
Query: 341 -----NSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIE 395
+ ++V +R + D+Q +KLQE P+ VP G+ P ++ L V LV + G R+
Sbjct: 202 EPCPLDPWMVVPDRSQYVDQQTLKLQENPEDVPTGELPRNMLLSVDRHLVQTIVPGTRLT 261
Query: 396 VSGIFRSIPIRSNPKQ-RALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNV 454
V GI+ S+ + ++ + YI VV ++ DT+ + N +
Sbjct: 262 VMGIYSIFQASSSSNSHKGAVAIRQPYIRVVGLE---------DTNEASSRGPANFTPDE 312
Query: 455 EEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKG 514
EE K+ A DVY + IAPSI+ +DVK+ LFGG+ K+ G
Sbjct: 313 EE----------EFKKFADSQDVYKNICTKIAPSIFGHEDVKRAAACLLFGGSRKSLPDG 362
Query: 515 GRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLV 574
+ RGDIN+LL GDPST+KSQ L++V K AP VYTSGKGSSA GLTA V RD T++
Sbjct: 363 VKLRGDINVLLLGDPSTAKSQFLKFVEKTAPIAVYTSGKGSSAAGLTASVIRDSSTREFY 422
Query: 575 LESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASA 634
LE GA+VL+DGGV CIDEFDKM R +HE MEQQTISIAKAGI T LN+RTS+LA+A
Sbjct: 423 LEGGAMVLADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAA 482
Query: 635 NPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDS 694
NP + RY+ +NIDL +LSRFDL+++V D + D+E+A H+ ++ S
Sbjct: 483 NPPSGRYDDLKTAQDNIDLQTTILSRFDLIFIVKDIRKYSQDKEIASHIIRVHASANKFS 542
Query: 695 VSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMR---KMGDDSRSDEKRIT 751
D +L YI Y + HP +++ A L R YV +R K + I
Sbjct: 543 DENTDSKEDNWLKRYIQYCRARCHPRLSKDAAENLQRKYVTIRMDMKRRAHETGEAAPIP 602
Query: 752 ATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATD------PKTGKID 805
T RQLE+++RLSE+ AKMRLS +DV++A +L ++ D A TG++
Sbjct: 603 ITVRQLEAIVRLSESLAKMRLSHEATPDDVDKAFKLFDTSTMDAARSGINQQINITGEMA 662
Query: 806 MNLVQT----------GKSVVQRKLLEDLAR 826
+ Q G + +R+L+EDLAR
Sbjct: 663 NEIKQAETQIKRRMGIGARLSERRLIEDLAR 693
>SPCC1682.02c [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 879
Score = 337 bits (863), Expect = 6e-92
Identities = 232/703 (33%), Positives = 369/703 (52%), Gaps = 91/703 (12%)
Query: 173 QEIFINETTDQEL-YYVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIA 231
QE ++T D + Y + +M +G L ++I L Y +L +L P E +
Sbjct: 18 QEYLEHDTDDANVTLYQEAILRMLNMGQRRLIVNIDELRDYNR--ELADGVLLKPLEYVE 75
Query: 232 IMDQTVKDCMVSLALDNGLESYLNEIESKLFKV--RPYNVETKKGMRELNPNDIDKLVSI 289
D+ +++ +VS +D + +++ KLF V R + R L ++K++S+
Sbjct: 76 PFDEALRN-VVSTLIDPVVHK---DLKDKLFYVGFRGSFGDHHVNPRTLRAMHLNKMISL 131
Query: 290 KGLVLRSTPIIPDMSVAFFKCNVCNHT-----VEVEIDRGIIQEPVRCPRVVCNSPNSMV 344
+G+V R + + P + + C + ++ G+ + P N N +
Sbjct: 132 EGIVTRCSFVRPKVIKSVHYCEATKRHHFKQYADATMNGGLSFQSTVYPTQDENG-NPLS 190
Query: 345 LVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIP 404
+ TF+D Q I LQE P+ P GQ P S+ + + D+LVD+ + GDR+ + G +RS+
Sbjct: 191 IEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLVDTVKPGDRVNIVGQYRSMG 250
Query: 405 IRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQ--IDNVEE-IRTLS 461
+++ A T+ V+ V LL N+ + NV ++
Sbjct: 251 SKTSGNTSA------TFRTVLLANNVV--------------LLGNKPGLGNVGGGALDIT 290
Query: 462 SEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDI 521
DIR I + AR+ +V+++LS S+APSIY + VK+ ILL L GG K G RGDI
Sbjct: 291 DADIRNINKLARKKNVFELLSTSLAPSIYGYEYVKQAILLLLLGGTEKNLTNGTHIRGDI 350
Query: 522 NILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALV 581
NIL+ GDPST+KSQ+L++V AP + T+G+GSS VGLTA VT D +T + LE+GA+V
Sbjct: 351 NILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTTDKETGERRLEAGAMV 410
Query: 582 LSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRY 641
L+D GV CIDEFDKM+D R +HEVMEQQT++IAKAGI T+LNAR S++A+ANPI +Y
Sbjct: 411 LADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPIYGQY 470
Query: 642 NPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLY------------LE 689
+ +NI LP +LSRFDL+++V D +++ DR L++H+ ++ +
Sbjct: 471 DIRKDPHQNIALPDSMLSRFDLLFIVTDDIDDKKDRALSEHVLRMHRYLPPGVEPGTPVR 530
Query: 690 DRPDSV--------------------------------------SQGDILPVEFLTAYIN 711
D +SV + ++L + F+ YI
Sbjct: 531 DSLNSVLNVGATNAAGVSTENVEQEVETPVWETFSSLLHANARTKKKELLNINFVRKYIQ 590
Query: 712 YAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRIT-ATTRQLESMIRLSEAHAKM 770
YAK IHP++ ++ + Y G+R DD + +++R + T R LE++IRLS AHAK
Sbjct: 591 YAKSRIHPILNQATAEYITNIYCGLR--NDDLQGNQRRTSPLTARTLETLIRLSTAHAKA 648
Query: 771 RLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDMNLVQTGK 813
RLS VE++D + A ++++ A+ PK K ++ G+
Sbjct: 649 RLSSVVEVKDAKAAEKILRYALFREVVKPKRKKHKKQRLEAGE 691
>YLR274w [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 775
Score = 335 bits (860), Expect = 1e-91
Identities = 235/774 (30%), Positives = 387/774 (49%), Gaps = 105/774 (13%)
Query: 154 SFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAYK 213
SF+ F++ F+L D + Y +QL + +L +++ +L+ Y
Sbjct: 30 SFKNFILEFRL-----------------DSQFIYRDQLRNNILVKNYSLTVNMEHLIGYN 72
Query: 214 HTEKLFHQILYYPQEIIAIMDQTVKDCMVSLAL----------DNGLESYLNEIESKLFK 263
E ++ ++ P +II + + + +++ D E+ + +S L
Sbjct: 73 --EDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLN 130
Query: 264 VRPY------NVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTV 317
P + + +R+L+ + K+V + G+++ ++ + + C C HT
Sbjct: 131 SLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTT 190
Query: 318 EVEIDR--GIIQEPVRCPRVVCNS-----------------------PNSMVLVHNRCTF 352
+ I+ I V PR ++ P+ +++H F
Sbjct: 191 SITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKF 250
Query: 353 QDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQR 412
D+Q +KLQE P+LVP G+ P ++++ L + G R+ + GI+ SI N
Sbjct: 251 IDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY-SIYNSKNGAGS 309
Query: 413 ALK---------SLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSE 463
++ YI ++ IQ V+TS++ + + EE LS
Sbjct: 310 GRSGGGNGGSGVAIRTPYIKILGIQS------DVETSSIWNSVTMFTEEEEEEFLQLS-- 361
Query: 464 DIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINI 523
R +Y++L+ SIAPSI+ +D+KK I+ L GG+ K G R RGDIN+
Sbjct: 362 ---------RNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINV 412
Query: 524 LLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLS 583
LL GDP T+KSQ+L++V K++P VYTSGKGSSA GLTA V RD T++ LE GA+VL+
Sbjct: 413 LLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLA 472
Query: 584 DGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNP 643
DGGV CIDEFDKM D R +HE MEQQTISIAKAGI T LN+RTS+LA+ANPI RY+
Sbjct: 473 DGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDD 532
Query: 644 NLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQ----GD 699
+NID +LSRFD++++V D NE D +A H+ +++ + +Q G
Sbjct: 533 LKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGS 592
Query: 700 ILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRK---MGDDSRSDEKRITATTRQ 756
+ +E + YI Y + P ++ A +L +V +RK + + ++ I T RQ
Sbjct: 593 EISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQ 652
Query: 757 LESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDMNLVQTGKSVV 816
LE++IR++E+ AK+ LS + V+EA+RL +++ D A+ G ++ +G S+
Sbjct: 653 LEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQ---ASGTSLS 709
Query: 817 Q-RKLLEDLAREI-------LKILTERTTDTISFNELSKLINEQSQDKVESIEL 862
+ R+ ++L R + + L DT F++L+ + +K E+I+L
Sbjct: 710 EIRRFEQELKRRLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQL 763
>ECU05g0780 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 726
Score = 335 bits (860), Expect = 1e-91
Identities = 215/597 (36%), Positives = 330/597 (55%), Gaps = 34/597 (5%)
Query: 275 MRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPR 334
+REL N + +L+S G V R+T + P++ F C +C ++ EP+ CP
Sbjct: 112 IRELKSNRLGQLLSFSGTVTRTTQVRPELVSGTFVCKICGSVIDNVFQEFKYTEPLTCPN 171
Query: 335 VVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRI 394
+C + L ++ F + Q I +QE + +P G P S+ + V ++LV+ RAGD++
Sbjct: 172 HLCTNRRLWKLDIDKSKFLNWQRIHVQENTEEIPPGSLPRSMDVIVRNDLVEKIRAGDKV 231
Query: 395 EVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQID-- 452
++G +P KS+ + I+K + ++ + +L I
Sbjct: 232 VMTGYLIVVPDVVQLMMPQSKSVPMQSGESDEIRK----KRNINIKDLNHKLSFMCIHAG 287
Query: 453 -NVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTF 511
+VEE ++E++ I E D+Y LS+S+ PSI+ +K ILL L GG K
Sbjct: 288 CSVEEDEEFTNEELATISEMRSTPDLYYKLSQSMFPSIHGHYSIKNAILLLLVGGVGKRA 347
Query: 512 KKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTK 571
+ G R RGDIN+LL GDP T+KSQ L+ PR VYTSGK SSA GLTA V +D +T
Sbjct: 348 EGGTRLRGDINMLLVGDPGTAKSQFLKQASAFLPRSVYTSGKSSSAAGLTASVVKDGETG 407
Query: 572 QLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSIL 631
+ +E+GAL+LSD GVCCIDEFDKMN + +HE MEQQTI+I+KAGI TLNAR+SIL
Sbjct: 408 EFTIEAGALMLSDTGVCCIDEFDKMNVKDQVSIHEAMEQQTITISKAGINATLNARSSIL 467
Query: 632 ASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDR 691
A+ANPI RY+ + +NI+L P++SRFDL ++++D + +DR +A H+ + +
Sbjct: 468 AAANPIKGRYDKKKTLRQNINLSAPVMSRFDLYFVLIDDADPENDRNVATHVLNSHA--- 524
Query: 692 PDSVSQGDILPVEF----LTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDE 747
SV+ +L F + Y+ YA++ P +T AK L++ YVG+R+ DS
Sbjct: 525 --SVTDSGVLASYFTREQVKLYLRYARKKT-PRMTAEAKEMLIKRYVGIRQ---DSLIHS 578
Query: 748 KRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAI-----KDYATDPKTG 802
T R LES+IRLSEA AK+ ++ V E VEEA RL+KS++ +D PKT
Sbjct: 579 NNYMMTVRHLESLIRLSEALAKVHDNDLVTKEYVEEAHRLVKSSVVEVKGEDIEIIPKTA 638
Query: 803 KIDMNLVQTGKSVVQRKLLEDLAREILKILTERTTDTISFNELSKLINEQSQDKVES 859
+ + + K V+ + + ++ +T + + EL + + +S+ +ES
Sbjct: 639 D-EPGFMVSSKDYVR------ITNSFIYLI--KTREPMERRELVEALLSESESSIES 686
>CE00415 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 810
Score = 333 bits (855), Expect = 5e-91
Identities = 224/669 (33%), Positives = 355/669 (52%), Gaps = 60/669 (8%)
Query: 153 NSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAY 212
N F +FL SFK DQ+ E Y + + ++ Q + + +++++L +
Sbjct: 22 NEFSKFLKSFK--------DQK--------NEFIYKSAMKELVQPEKNTIFINMQHLYKF 65
Query: 213 KHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVETK 272
+ ++ YY + M + + LD ES ++ K V +N++ K
Sbjct: 66 SNNLATTIELQYY--RVYPFMCEALH----LATLDACDESERQQMFKKQLYVSLFNLDAK 119
Query: 273 KGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRC 332
+REL+ + + LV I G ++R+ P+ P++S A F C C T + +P +C
Sbjct: 120 TKVRELSADKVGGLVRIAGQIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKC 179
Query: 333 PRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGD 392
C + L N TF D Q I++QET +P G P +V + V E+V++ + GD
Sbjct: 180 ANPQCMNRTRFSLDVNSSTFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGD 239
Query: 393 RIEVSGIFRSIPI---RSNPKQRA-------------------LKSL------YKTYIDV 424
+ ++ G IP S P RA LK+L YK
Sbjct: 240 KCDIVGTLIVIPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLA 299
Query: 425 VHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRS 484
HIQ+ + VG D S ++ D ++ +S+ED +K+ + + + S
Sbjct: 300 CHIQQT-ESLVGGDASGAVEET-----DYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDS 353
Query: 485 IAPSIYELDDVKKGILLQLFGG-ANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKI 543
+ P+IY +VK G+LL L GG A K+ +G RGDIN+ L GDPST+KSQ+L+ V +
Sbjct: 354 LFPNIYGNHEVKLGVLLMLLGGVAKKSRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEF 413
Query: 544 APRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSV 603
+PR +YTSGK SSA GLTA V +D ++ + V+E+GAL+L+D GVCCIDEFDKM+ +
Sbjct: 414 SPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVA 473
Query: 604 LHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDL 663
+HE MEQQTISI KAG+ TLNAR SILA+ANP+N RY+ + P+ N+ + P++SRFDL
Sbjct: 474 IHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDL 533
Query: 664 VYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITE 723
++++D+ NE +D +A+ + + + + + ++ + YI +A+ P I++
Sbjct: 534 FFVLVDECNEVTDYAIARRILDNH-RAISEHTERDSVYKIDDIKKYIAFAR-CFKPKISD 591
Query: 724 SAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEE 783
A LVR Y +R M D + + T RQLES++RLSEA A++ + V +E VE+
Sbjct: 592 KAAETLVREYKKLR-MSDSNNAATSSWRITVRQLESLVRLSEALARLHCGKEVLVEHVEK 650
Query: 784 AVRLIKSAI 792
A L+ +I
Sbjct: 651 AAELLNKSI 659
>7299365 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 733
Score = 333 bits (853), Expect = 9e-91
Identities = 226/673 (33%), Positives = 365/673 (53%), Gaps = 68/673 (10%)
Query: 146 VSIQECGNSFREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLD 205
+++Q ++EF+ +F +++ F + Y+N G L ++
Sbjct: 25 INLQAVKKKYKEFIRTF--------NEENFFYKYRDTLKRNYLN--------GRYFLEIE 68
Query: 206 IRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGL-ESYLNEIESKLFK- 263
+ +L+ + T L ++ P E + I ++ ++ + E ++++I+ L
Sbjct: 69 MEDLVGFDET--LADKLNKQPTEHLEIFEEAAREVADEITAPRPEHEEHMHDIQILLSSN 126
Query: 264 VRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTV-EVEID 322
P N+ R+L + + KLV I G+++ ++ I + +C C+ + ++++
Sbjct: 127 ANPTNI------RQLKSDCVSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLKVN 180
Query: 323 RGIIQEPVRCPRVVCNSPNS---------MVLVHNRCTFQDRQVIKLQETPDLVPDGQTP 373
G+ E PR CN+ + ++ ++C D Q +KLQE PD VP G+ P
Sbjct: 181 PGL--EGYALPRK-CNTEQAGRPKCPLDPFFIMPDKCKCVDFQTLKLQELPDFVPQGEIP 237
Query: 374 HSVSLCVYDELVDSCRAGDRIEVSGIF--RSI--PIRSNPKQRALKSLYKTYIDVVHIQK 429
+ L L + G+R+ + GI+ R + P R + +++A+ + Y+ VV I
Sbjct: 238 RHLQLFCDRSLCERVVPGNRVLIQGIYSIRKVGKPSRRDGREKAVVGVRAPYMRVVGIT- 296
Query: 430 VAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSI 489
V + G + ++S++ + A D+Y+ LS+S+APSI
Sbjct: 297 VDSEGAGA----------------ISRYSNITSDEEEHFRRMAASGDIYERLSQSLAPSI 340
Query: 490 YELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVY 549
+ D+KK I LFGG+ K G RGDIN+LL GDP T+KSQ+L++V K+AP VY
Sbjct: 341 FGSRDIKKAITCMLFGGSRKRLPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVY 400
Query: 550 TSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVME 609
TSGKGSSA GLTA V +D T+ V+E GA+VL+DGGV CIDEFDKM ++ R +HE ME
Sbjct: 401 TSGKGSSAAGLTASVMKDPQTRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAME 460
Query: 610 QQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLD 669
QQTISIAKAGI TTLN+R S+LA+AN I R++ + ENID P +LSRFD++++V D
Sbjct: 461 QQTISIAKAGITTTLNSRCSVLAAANSIFGRWD-DTKGEENIDFMPTILSRFDMIFIVKD 519
Query: 670 KVNEASDRELAKHLTSLYL---EDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAK 726
+E+ D LAKH+ +++L + P ++G+I + YI+Y + + P ++E+A
Sbjct: 520 IHDESRDITLAKHIINVHLSSNKSAPSEPAEGEI-SLSTFKKYIHYCRTHCGPRLSEAAG 578
Query: 727 TELVRAYVGMRK-MGDDSRSDEKR--ITATTRQLESMIRLSEAHAKMRLSERVELEDVEE 783
+L YV MR G ++ +KR I T RQLE++IR+SE+ AK+RL E V E
Sbjct: 579 EKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISESLAKIRLQPFATDEHVNE 638
Query: 784 AVRLIKSAIKDYA 796
A+RL + + D A
Sbjct: 639 ALRLFQVSTLDAA 651
>7295030 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 720
Score = 330 bits (845), Expect = 8e-90
Identities = 211/543 (38%), Positives = 303/543 (54%), Gaps = 36/543 (6%)
Query: 255 NEIESKLFK-----VRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFK 309
N S+L K +P + E +RE+ I KLV+++G+V R T + P M VA +
Sbjct: 124 NSFPSELMKRFEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYT 183
Query: 310 CNVCNHTVEVEIDRGIIQEPVRCPRVVC--NSPNSMVLVHNRCT-FQDRQVIKLQETPDL 366
C+ C ++ CP C N + + R + F Q +K+QE D
Sbjct: 184 CDRCGSETYQPVNSLSFTPVHDCPSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQ 243
Query: 367 VPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVH 426
VP G P S+++ E+ + GD I VSG+F + +R+ Q L +T++
Sbjct: 244 VPVGHIPRSMTIMCRGEVTRMAQPGDHIVVSGVFLPL-MRTGFAQMIQGLLSETFLQAHR 302
Query: 427 IQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIA 486
I + K+ +EI +E E + D Y+ L+ S+A
Sbjct: 303 IICINKN---------------------DEISDKDAELTPEELEELAQDDFYERLATSLA 341
Query: 487 PSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPR 546
P IY DVKK +LL L GG +K G + RG+INI L GDP +KSQ+L Y+ ++A R
Sbjct: 342 PEIYGHLDVKKALLLLLVGGVDKR-PDGMKIRGNINICLMGDPGVAKSQLLGYISRLAVR 400
Query: 547 GVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHE 606
YT+G+GSS VGLTA V +D T ++ LE GALVL+D GVCCIDEFDKM D R+ +HE
Sbjct: 401 SQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCIDEFDKMADQDRTAIHE 460
Query: 607 VMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYL 666
VMEQQTISIAKAGI+TTLNAR SILA+ANP RYNP V +NI LP LLSRFDL++L
Sbjct: 461 VMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAALLSRFDLLWL 520
Query: 667 VLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAK 726
+ DK + +D LAKH+T ++ + ++ L + + YIN K+ +P I +
Sbjct: 521 IQDKPDRDNDLRLAKHITYVHSHSK-QPPTRVKALDMNLMRRYINLCKRK-NPTIPDELT 578
Query: 727 TELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVR 786
+V AYV +R+ ++R+ + + R L ++RLS A A++RLS+ VE +DV EA+R
Sbjct: 579 DYIVGAYVELRR---EARNQKDMTFTSARNLLGILRLSTALARLRLSDSVEKDDVAEALR 635
Query: 787 LIK 789
L++
Sbjct: 636 LLE 638
>CE03558 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 759
Score = 329 bits (843), Expect = 1e-89
Identities = 210/577 (36%), Positives = 314/577 (54%), Gaps = 69/577 (11%)
Query: 270 ETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTV-EVEIDRGIIQE 328
E +R++ + ++V I G+++ + + + +C C HT+ +V I G+ E
Sbjct: 132 EYPTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIPDVSIKPGL--E 189
Query: 329 PVRCPRVVCNSPNS----------MVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSL 378
PR C +P +++ ++C D Q +KLQE P+ VP G+ P + L
Sbjct: 190 GFALPRT-CAAPQQGQMQRCPIDPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQL 248
Query: 379 CVYDELVDSCRAGDRIEVSGIFRSIP--IRSNPKQRALKSLYKTYIDV--VHIQKVAKDR 434
L D G+R+ + G++ SI I+ ++L+ + Y+ V +H++ R
Sbjct: 249 FTERYLTDKVVPGNRVTIVGVY-SIKKLIQKKGGDKSLQGIRTPYLRVLGIHMETSGPGR 307
Query: 435 VGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDD 494
T T E++ R K A+R D Y+++++SIAPSIY D
Sbjct: 308 TNFTTFTPEEE--------------------RMFKTLAQRKDAYELIAKSIAPSIYGSAD 347
Query: 495 VKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKG 554
+KK I LFGGA K G RGDIN+LL GDP T+KSQ+L++V +++P GVYTSGKG
Sbjct: 348 IKKSIACLLFGGARKKLPDGITRRGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKG 407
Query: 555 SSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTIS 614
SSA GLTA V RD ++ ++E GA+VL+DGGV CIDEFDKM ++ R +HE MEQQTIS
Sbjct: 408 SSAAGLTASVIRDPQSRSFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTIS 467
Query: 615 IAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEA 674
IAKAGI TTLN+R S+LA+AN + R++ + +NID P +LSRFD++Y+V D +
Sbjct: 468 IAKAGITTTLNSRCSVLAAANSVYGRWDESRG-DDNIDFMPTILSRFDMIYIVKDTHDVL 526
Query: 675 SDRELAKHLTSLYLE------------------DRPDSVSQGD---ILPVEFLTAYINYA 713
D LAKH+ +++ D ++ D L +EFL ++ YA
Sbjct: 527 KDATLAKHVIEVHVNASAAKERDIAGVPKTATTDSDGVMTMFDTDGFLTIEFLKKFVTYA 586
Query: 714 KQNIHPVITESAKTELVRAYVGMRK---MGDDSRSDEK----RITATTRQLESMIRLSEA 766
+ N P +T A +LV YV MR D +S +K I T RQLE+++R++E+
Sbjct: 587 RLNCGPRLTPQASEKLVNHYVKMRNPVVNADAFKSGKKAHNSAIPITVRQLEAIVRIAES 646
Query: 767 HAKMRLSERVELEDVEEAVRLIK-SAIKDYATDPKTG 802
AKM L + + VEEA+RL + S I+ AT G
Sbjct: 647 IAKMELQQFATDKHVEEALRLFRVSTIEAAATGNLAG 683
>SPBC4.04c [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 830
Score = 328 bits (840), Expect = 3e-89
Identities = 219/632 (34%), Positives = 335/632 (52%), Gaps = 52/632 (8%)
Query: 176 FINETTDQE--LYYVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIM 233
F+ E TD+ Y N++ + ++ +L ++ +L K F + P I I
Sbjct: 207 FLLEYTDENGTSVYGNRIRTLGEVNAESLMVNYAHLGESKPILAYF--LANAPAPIFRIF 264
Query: 234 DQTVKDCMVSLALDNGLESY--LNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKG 291
D+ +AL+ L Y I S + VR N+ T +R+L + ++ LV + G
Sbjct: 265 DR--------VALEATLLHYPDYERIHSDIH-VRITNLPTCFTLRDLRQSHLNCLVRVSG 315
Query: 292 LVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVR-CPRVVCNSPNSMVLVHNRC 350
+V R T + P + F C C T+ ++ + C C+S V+ R
Sbjct: 316 VVTRRTGLFPQLKYIRFTCTKCGATLGPFFQDSSVEVKISFCHN--CSSRGPFVINSERT 373
Query: 351 TFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPK 410
+ + Q I LQE+P VP G+ P + + +LVD + G+ I+V+GI+R+ S
Sbjct: 374 VYNNYQRITLQESPGTVPSGRLPRHREVILLADLVDVAKPGEEIDVTGIYRNNFDASLNT 433
Query: 411 QRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKE 470
+ ++ T I+ HI ++ D S D+ + L+ ++ R I+
Sbjct: 434 KNGFP-VFATIIEANHISQL-------DGS--------GNTDDDFSLSRLTDDEEREIRA 477
Query: 471 TARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPS 530
A+ D+++ + S+APSIY +K I LFGG K + RGDIN+LL GDP
Sbjct: 478 LAKSPDIHNRIIASMAPSIYGHRSIKTAIAAALFGGVPKNINGKHKIRGDINVLLLGDPG 537
Query: 531 TSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCI 590
T+KSQ L+YV K A R V+ +G+G+SAVGLTA V +D T + LE GALVL+D GVC I
Sbjct: 538 TAKSQFLKYVEKTAHRAVFATGQGASAVGLTASVRKDPITNEWTLEGGALVLADKGVCLI 597
Query: 591 DEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTEN 650
DEFDKMND R+ +HE MEQQ+ISI+KAGI+TTL AR +I+A+ANPI RYN +P +N
Sbjct: 598 DEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCTIIAAANPIGGRYNTTIPFNQN 657
Query: 651 IDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDIL--------- 701
++L P+LSRFD++ +V D VN D +LA + S ++ P D+L
Sbjct: 658 VELTEPILSRFDILQVVKDTVNPEIDEQLANFVVSSHIRSHPAFDPNMDVLKKVPTETGI 717
Query: 702 -----PVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQ 756
P + L YI++A++ + P + + + ++ R Y MR+ + S T R
Sbjct: 718 DAKPIPQDLLRKYIHFAREKVFPRLQQMDEEKISRLYSDMRRESLATGS----YPITVRH 773
Query: 757 LESMIRLSEAHAKMRLSERVELEDVEEAVRLI 788
LES IRLSEA AKM+LSE V +++A+++I
Sbjct: 774 LESAIRLSEAFAKMQLSEFVRPSHIDKAIQVI 805
>7290738 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 817
Score = 328 bits (840), Expect = 3e-89
Identities = 206/550 (37%), Positives = 303/550 (54%), Gaps = 38/550 (6%)
Query: 269 VETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQE 328
V T+ +R+L + I L+ I G V+R+ P+ P++ F C C + +
Sbjct: 111 VPTRHKVRDLTTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTN 170
Query: 329 PVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSC 388
P C VC++ +L + F D Q I++QET +P G P +V + + ELV++
Sbjct: 171 PTICRNPVCSNRKRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETV 230
Query: 389 RAGDRIEVSGIFRSIP---------------IRSNPKQ-----RALKSL------YKTYI 422
+AGDR + +G +P R P + LK+L Y+
Sbjct: 231 QAGDRYDFTGTLIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAF 290
Query: 423 DVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLS 482
+Q G D L +++ + + ++ + +I E ++ ++Y L
Sbjct: 291 LACSVQATTARFGGTD-------LPMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLI 343
Query: 483 RSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHK 542
S+ PSIY D+VK+GILLQ FGG KT + RGDIN+ + GDPST+KSQ L+ V
Sbjct: 344 SSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSD 403
Query: 543 IAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRS 602
+PR +YTSGK SSA GLTA V RD ++ V+E+GAL+L+D G+CCIDEFDKM+ +
Sbjct: 404 FSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQV 463
Query: 603 VLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFD 662
+HE MEQQTISIA+AG+ TLNARTSILA+ANPIN RY+ + + +NI L P++SRFD
Sbjct: 464 AIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFD 523
Query: 663 LVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVIT 722
L ++++D+ NE D +A+ + L+ + +SV + E + Y+ +A+Q PVI+
Sbjct: 524 LFFILVDECNEVVDYAIARKIVDLH-SNIEESVERA--YTREEVLRYVTFARQ-FKPVIS 579
Query: 723 ESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVE 782
+ A LV Y G + D S T RQLESMIRLSEA AK+ S RV V+
Sbjct: 580 QEAGHMLVENY-GHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVK 638
Query: 783 EAVRLIKSAI 792
EA RL+ +I
Sbjct: 639 EAFRLLNKSI 648
>At1g44900 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 928
Score = 325 bits (833), Expect = 2e-88
Identities = 206/639 (32%), Positives = 335/639 (52%), Gaps = 61/639 (9%)
Query: 226 PQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDK 285
PQ ++ +M++ + + L +Y N I +K++ VR N+ +R + ++
Sbjct: 270 PQPVLEVMEEVSEKVIFDLH-----PNYKN-IHTKIY-VRVTNLPVNDQIRNIRQIHLNT 322
Query: 286 LVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPV-RCPRVVCNSPNSMV 344
++ I G+V R + + P + + CN C + + V C C S
Sbjct: 323 MIRIGGVVTRRSGVFPQLQQVKYDCNKCGAVLGPFFQNSYSEVKVGSCSE--CQSKGPFT 380
Query: 345 LVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIF-RSI 403
+ + +++ Q + +QE+P VP G+ P + + ++L+D R G+ IEV+GI+ +
Sbjct: 381 VNVEQTIYRNYQKLTIQESPGTVPAGRLPRHKEVILLNDLIDCARPGEEIEVTGIYTNNF 440
Query: 404 PIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSE 463
+ N K + + VV V K + ++ L+ E
Sbjct: 441 DLSLNTKNG-----FPVFATVVEANYVTKKQ------------------DLFSAYKLTQE 477
Query: 464 DIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINI 523
D +I+E ++ + + + +SIAPSIY +D+K + L +FGG K K R RGDIN+
Sbjct: 478 DKTQIEELSKDPRIVERIIKSIAPSIYGHEDIKTALALAMFGGQEKNIKGKHRLRGDINV 537
Query: 524 LLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLS 583
LL GDP T+KSQ L+YV K R VYT+GKG+SAVGLTA V +D T++ LE GALVL+
Sbjct: 538 LLLGDPGTAKSQFLKYVEKTGQRAVYTTGKGASAVGLTAAVHKDPVTREWTLEGGALVLA 597
Query: 584 DGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNP 643
D G+C IDEFDKMND R +HE MEQQ+ISI+KAGI+T+L AR S++A+ANP+ RY+
Sbjct: 598 DRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPVGGRYDS 657
Query: 644 NLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGD---- 699
+ +N++L P+LSRFD++ +V D V+ +D LA+ + + + + +P D
Sbjct: 658 SKSFAQNVELTDPILSRFDILCVVKDVVDPVTDEMLAEFVVNSHFKSQPKGGKMEDSDPE 717
Query: 700 -------------ILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSD 746
+LP L Y+ Y+K + P + E +L Y +R+ + +
Sbjct: 718 DGIQGSSGSTDPEVLPQNLLKKYLTYSKLYVFPKLGELDAKKLETVYANLRRESMNGQG- 776
Query: 747 EKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDM 806
++ TR LESMIR+SEAHA+M L + V EDV A+R++ + + + K G +
Sbjct: 777 ---VSIATRHLESMIRMSEAHARMHLRQYVTEEDVNMAIRVL---LDSFISTQKFG-VQR 829
Query: 807 NLVQTGKSVVQRKLLEDLAREILKILTERTTDTISFNEL 845
L ++ K + K +D +L +L E + + F E+
Sbjct: 830 TLRESFKRYITYK--KDFNSLLLVLLKELVKNALKFEEI 866
>Hs7427519 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 821
Score = 324 bits (830), Expect = 4e-88
Identities = 200/557 (35%), Positives = 317/557 (56%), Gaps = 30/557 (5%)
Query: 259 SKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVE 318
+K F V ++ T+ +REL + I L I G V+R+ P+ P++ F C C +
Sbjct: 107 AKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIR 166
Query: 319 VEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSL 378
+ +P C VC + +L N+ F D Q +++QET +P G P S+ +
Sbjct: 167 DVEQQFKYTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEV 226
Query: 379 CVYDELVDSCRAGDRIEVSGIFRSIPI---RSNPKQRALKSLYKTYIDVVHIQKVAKDR- 434
+ E V+S +AGD+ + +G +P S P RA + + +D + + R
Sbjct: 227 ILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRA 286
Query: 435 ----------------VGVDTSTVEQQLLQNQIDNVEEIRT-LSSEDIRRIKETARRSDV 477
V + L+++ E I+ ++ ++ ++ E ++ ++
Sbjct: 287 LGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNL 346
Query: 478 YDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQIL 537
Y L S+ P+I+ D+VK+G+LL LFGG KT +G RGDIN+ + GDPST+KSQ L
Sbjct: 347 YHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFL 406
Query: 538 QYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMN 597
++V + +PR VYTSGK SSA GLTA V RD ++ + V+E+GAL+L+D GVCCIDEFDKM+
Sbjct: 407 KHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMD 466
Query: 598 DNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPL 657
+ +HE MEQQTISI KAG+ TLNARTSILA+ANPI+ Y+ + + +NI+L P+
Sbjct: 467 VRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNINLSAPI 526
Query: 658 LSRFDLVYLVLDKVNEASDRELAKHLTSLY--LEDRPDSVSQGDILPVEFLTAYINYAKQ 715
+SRFDL ++++D+ NE +D +A+ + L+ +E+ D V ++ + Y+ +A+Q
Sbjct: 527 MSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRV-----YSLDDIRRYLLFARQ 581
Query: 716 NIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSER 775
P I++ ++ +V Y +R+ D S + T RQLESMIRLSEA A+M +
Sbjct: 582 -FKPKISKESEDFIVEQYKHLRQR-DGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDE 639
Query: 776 VELEDVEEAVRLIKSAI 792
V+ + V+EA RL+ +I
Sbjct: 640 VQPKHVKEAFRLLNKSI 656
>Hs6631095 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 808
Score = 322 bits (824), Expect = 2e-87
Identities = 250/842 (29%), Positives = 403/842 (47%), Gaps = 173/842 (20%)
Query: 170 LDDQEI---------FINETTDQELYYVNQLNQMRQLGTSN---LNLDIRNLLAYKHTEK 217
LDD E+ F+++ DQ +Y +++R+L + N L +++ +L + EK
Sbjct: 7 LDDVELREAQRDYLDFLDDEEDQGIYQ----SKVRELISDNQYRLIVNVNDLR--RKNEK 60
Query: 218 LFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVETKKGMRE 277
+++L E + + +KD + S+ +Y + E F V +E G +
Sbjct: 61 RANRLLNNAFEELVAFQRALKDFVASIDA-----TYAKQYEE--FYV---GLEGSFGSKH 110
Query: 278 LNPNDIDK-----LVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEID--RGIIQEPV 330
++P + +V ++G+V + + + P + + C T+E ++ P
Sbjct: 111 VSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPS 170
Query: 331 RCPRVVCNSPNS-MVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCR 389
+ N+ + + ++D Q I +QE P+ P GQ P SV + + D+LVD +
Sbjct: 171 SSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAK 230
Query: 390 AGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQN 449
GDR++V G +R +P K ++T + ++++++KD
Sbjct: 231 PGDRVQVVGTYRCLP---GKKGGYTSGTFRTVLIACNVKQMSKDAQP------------- 274
Query: 450 QIDNVEEIRTLSSEDIRRIKETA--RRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGA 507
+ S+EDI +IK+ + R D++D L++S+APSI+ D VKK IL L GG
Sbjct: 275 ---------SFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGV 325
Query: 508 NKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRD 567
+ + G RGDINILL GDPS +KSQ+L+YV APR + T+G+GSS VGLTA VT D
Sbjct: 326 ERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTD 385
Query: 568 VDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNAR 627
+T + LE+GA+VL+D GV CIDEFDKM+D R+ +HEVMEQ ++IAKAGI LNAR
Sbjct: 386 QETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNAR 445
Query: 628 TSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLY 687
S+LA+ANP+ RY+ ENI L LLSRFDL++++LD+++ DRE++ H+ ++
Sbjct: 446 CSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMH 505
Query: 688 LEDRPDSVSQGDILPV-------------------------------------------- 703
P GD +P+
Sbjct: 506 RYRAPGE-QDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVS 564
Query: 704 -EFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIR 762
F+ YI+ AK I PV+T+ + T + Y +R S + T R LE++IR
Sbjct: 565 AAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIR 623
Query: 763 LSEAHAKMRLSERVELEDVEEAVRLIKSAI------------------------------ 792
L+ AHAK R+S+ V+L+D EEAV L++ A
Sbjct: 624 LATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQE 683
Query: 793 ---------KDYATDPKTG-----------KIDMNLVQTGKSVVQRKLLE----DLAREI 828
K D K G + +M V T K+ ++ E +L+
Sbjct: 684 DQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESR 743
Query: 829 LK--------ILTERTTDTISFNELSKLINEQSQDKVESIELSNALTRLQQEDKVVILGE 880
LK + E +I N L++ IN S++ S+E+ AL+++ Q+D V++ E
Sbjct: 744 LKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKM-QDDNQVMVSE 802
Query: 881 GL 882
G+
Sbjct: 803 GI 804
>HsM14149623 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 543
Score = 320 bits (820), Expect = 6e-87
Identities = 198/490 (40%), Positives = 285/490 (57%), Gaps = 31/490 (6%)
Query: 303 MSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVCNSPNS---MVLVHNRCTFQDRQVIK 359
M VA + C+ C I + CP C + S + L F Q +K
Sbjct: 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 60
Query: 360 LQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYK 419
+QE D VP G P S+++ V E + GD + V+GIF I +R+ +Q L +
Sbjct: 61 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI-LRTGFRQVVQGLLSE 119
Query: 420 TYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYD 479
TY++ I K+ K D+ L+ E++R+I E D Y+
Sbjct: 120 TYLEAHRIVKMNKSE-----------------DDESGAGELTREELRQIAE----EDFYE 158
Query: 480 VLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQY 539
L+ SIAP IY +DVKK +LL L GG +++ +G + RG+INI L GDP +KSQ+L Y
Sbjct: 159 KLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSY 217
Query: 540 VHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDN 599
+ ++APR YT+G+GSS VGLTA V RD + +L LE GALVL+D GVCCIDEFDKM +
Sbjct: 218 IDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEA 277
Query: 600 TRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLS 659
R+ +HEVMEQQTISIAKAGI+TTLNAR SILA+ANP RYNP + +NI LP LLS
Sbjct: 278 DRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLS 337
Query: 660 RFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHP 719
RFDL++L+ D+ + +D LA+H+T ++ R SQ + L ++ + YI ++ P
Sbjct: 338 RFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR-QPPSQFEPLDMKLMRRYIAMCREK-QP 395
Query: 720 VITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELE 779
++ ES + AYV MR+ ++ + + + R L +++RLS A A++R+ + VE E
Sbjct: 396 MVPESLADYITAAYVEMRR---EAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKE 452
Query: 780 DVEEAVRLIK 789
DV EA+RL++
Sbjct: 453 DVNEAIRLME 462
>YBL023c [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 868
Score = 319 bits (818), Expect = 1e-86
Identities = 217/686 (31%), Positives = 349/686 (50%), Gaps = 74/686 (10%)
Query: 153 NSFREFLMSFKLKYRKELDDQEIFINETTDQ--ELYYVNQLNQMRQLGTSNLNLDIRNLL 210
NS+ E++ + R + + F+ E TD+ Y ++ + ++ + +L ++ R+L
Sbjct: 192 NSYSEWITQPNVS-RTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLA 250
Query: 211 AYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVE 270
K LF + P+E++ I D + A + Y I S++ VR +
Sbjct: 251 ESKAILALF--LAKCPEEMLKIFDLVAME-----ATELHYPDYAR-IHSEIH-VRISDFP 301
Query: 271 TKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPV 330
T +REL +++ LV + G+V R T + P + F C C + E +
Sbjct: 302 TIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDS--NEEI 359
Query: 331 RCPRVV-CNSPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCR 389
R C S + + +++ Q + LQE P VP G+ P + + +LVD +
Sbjct: 360 RISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSK 419
Query: 390 AGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQN 449
G+ +EV+GI+++ + K+ + + ++ + K R G + E+ L
Sbjct: 420 PGEEVEVTGIYKN----NYDGNLNAKNGFPVFATIIEANSI-KRREGNTANEGEEGL--- 471
Query: 450 QIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANK 509
++ + + E+ R ++ +R + D + S+APSIY D+K + LFGG K
Sbjct: 472 ------DVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPK 525
Query: 510 TFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVD 569
RGDIN+LL GDP T+KSQIL+YV K A R V+ +G+G+SAVGLTA V +D
Sbjct: 526 NVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPI 585
Query: 570 TKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTS 629
TK+ LE GALVL+D GVC IDEFDKMND R+ +HE MEQQ+ISI+KAGI+TTL AR S
Sbjct: 586 TKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCS 645
Query: 630 ILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLE 689
I+A+ANP RYN LP+ +N+ L P+LSRFD++ +V D V+E +D LA + ++
Sbjct: 646 IIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVR 705
Query: 690 DRPD----------------SVSQGD-------------------------ILPVEFLTA 708
P+ ++ QG+ +P E L
Sbjct: 706 SHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMK 765
Query: 709 YINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHA 768
YI+YA+ I+P + + ++ R Y +R+ + S T R LES++R++E+ A
Sbjct: 766 YIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGS----FPITVRHLESILRIAESFA 821
Query: 769 KMRLSERVELEDVEEAVRLIKSAIKD 794
KMRLSE V D++ A++++ + D
Sbjct: 822 KMRLSEFVSSYDLDRAIKVVVDSFVD 847
>Hs11418031 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 734
Score = 318 bits (815), Expect = 2e-86
Identities = 219/661 (33%), Positives = 348/661 (52%), Gaps = 62/661 (9%)
Query: 155 FREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAYKH 214
F+EFL +++ + T Y ++L + LG + +++ +L ++
Sbjct: 35 FKEFLRQYRVG------------TDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFD- 81
Query: 215 TEKLFHQILYYPQEIIAIMDQTVKDCM--VSLALDNGLESYLNEIESKLFKVRPYNVETK 272
E L + P E + ++++ K+ V+ +G E L +I+ L + +
Sbjct: 82 -EDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVML-----KSDASP 134
Query: 273 KGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTV-EVEIDRGIIQEPVR 331
+R L + + LV I G+++ ++ + + +C C +T+ + + G+ E
Sbjct: 135 SSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGL--EGYA 192
Query: 332 CPRVVCNSPNS---------MVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYD 382
PR CN+ + ++ ++C D Q +KLQE PD VP G+ P + L
Sbjct: 193 LPRK-CNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDR 251
Query: 383 ELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTV 442
L D G+R+ + GI+ ++K T +DRVGV +
Sbjct: 252 YLCDKVVPGNRVTIMGIY------------SIKKFGLT-------TSRGRDRVGVGIRSS 292
Query: 443 EQQLLQNQIDNVEEIRT----LSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKG 498
++L Q+D R+ +S ++ + A +VY+V+S+SIAPSI+ D+KK
Sbjct: 293 YIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKA 352
Query: 499 ILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAV 558
I LFGG+ K G RGDIN+L+ GDP T+KSQ+L++V K +P GVYTSGKGSSA
Sbjct: 353 IACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAA 412
Query: 559 GLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKA 618
GLTA V RD ++ ++E GA+VL+DGGV CIDEFDKM ++ R +HE MEQQTISIAKA
Sbjct: 413 GLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKA 472
Query: 619 GIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRE 678
GI TTLN+R S+LA+AN + R++ +NID P +LSRFD++++V D+ NE D
Sbjct: 473 GITTTLNSRCSVLAAANSVFGRWD-ETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVM 531
Query: 679 LAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRK 738
LAKH+ +L++ + + + + L +I Y + P ++ A +L Y+ MR
Sbjct: 532 LAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRS 591
Query: 739 MGDDSRSDEKR---ITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDY 795
D R I T RQLE+++R++EA +KM+L DVEEA+RL + + D
Sbjct: 592 GARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDA 651
Query: 796 A 796
A
Sbjct: 652 A 652
>ECU06g0340 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 696
Score = 318 bits (815), Expect = 2e-86
Identities = 210/645 (32%), Positives = 339/645 (52%), Gaps = 104/645 (16%)
Query: 179 ETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVK 238
+TT +E +V N + N +L ++ Y++++ L ++ P+ I ++ V
Sbjct: 37 KTTHKEYSHVLSSN----INQDNFSLTVKLEHIYQYSDLLSRELSRRPERAIEWFEEAVA 92
Query: 239 DCMVSLALDNGLESYLNEIESKLFKVRPYNVETKKG-------------MRELNPNDIDK 285
D YNV+ +G +RE+N + +K
Sbjct: 93 D--------------------------RYNVKGVQGFQLCLVSDGRCIPIREINASKTNK 126
Query: 286 LVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVCNSPNSMVL 345
+V I+G+V+ ++ +I F C C + EV + P C + C P+ ++
Sbjct: 127 IVKIQGIVVSASSVITKPRTLFLVCRNCLSSKEV-----MDMIPRMCDKTEC-PPDPYIV 180
Query: 346 VHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPI 405
+ + D Q +K+QE + +P G+TP SL + ++V+ G ++ ++GI+
Sbjct: 181 IPEKSQVIDVQYVKIQEFFEDIPVGETPRHFSLVLEKKMVNRLIPGSKVVITGIY----- 235
Query: 406 RSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDI 465
++ + + + +V + VG++ +++ + + + E + LS
Sbjct: 236 -------CMRMIRDSSLPIVKV-------VGLEDRSLKTSKMFTE-EEEESFKKLS---- 276
Query: 466 RRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILL 525
++D+Y+ +SRSIAPS+Y +DVK+ + LFGG + + RGDIN+LL
Sbjct: 277 --------KADIYERISRSIAPSVYGHEDVKRALACMLFGGTRRVLEDKVTLRGDINVLL 328
Query: 526 CGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDG 585
GDP +KSQ+L+++ ++P GVYTSGKGSSA GLTA V RD + LE GALVL+D
Sbjct: 329 LGDPGMAKSQLLKFMELVSPVGVYTSGKGSSAAGLTASVIRD-SGGEFYLEGGALVLADN 387
Query: 586 GVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNL 645
G+CCIDEFDKM+++ R +HE MEQQTISIAKAGI T LN RTSILA+ANP+ RY+
Sbjct: 388 GICCIDEFDKMDEHDRVAIHEAMEQQTISIAKAGITTMLNTRTSILAAANPVFGRYDDYK 447
Query: 646 PVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYL--------------EDR 691
ENI+ +LSRFD ++++ DK + +D LAKH+ S++ +D+
Sbjct: 448 TPDENIEFGATILSRFDCIFILKDK-HGPNDIILAKHVLSVHQNKAREDNECQNGLHDDQ 506
Query: 692 PDSVS----QGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRK---MGDDSR 744
+ +S DI+P+ + Y+ YA+ + P ++E+A +L R YV RK + S
Sbjct: 507 EEQISGSDRSPDIIPIHTIKRYVQYARSKVFPTLSEAASKQLSRYYVNTRKEVRQLEQST 566
Query: 745 SDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIK 789
I T RQLE++IR+ E+ AKM LS+ V + VEEA+RL K
Sbjct: 567 LKRNAIPITVRQLEAIIRIGESLAKMELSQIVTEKHVEEAIRLFK 611
>Hs6981192 [L] KOG0481 DNA replication licensing factor MCM5 component
Length = 733
Score = 315 bits (808), Expect = 2e-85
Identities = 218/660 (33%), Positives = 348/660 (52%), Gaps = 61/660 (9%)
Query: 155 FREFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAYKH 214
F+EFL +++ + T Y ++L + LG + +++ +L ++
Sbjct: 35 FKEFLRQYRVG------------TDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFD- 81
Query: 215 TEKLFHQILYYPQEIIAIMDQTVKDCM--VSLALDNGLESYLNEIESKLFKVRPYNVETK 272
E L + P E + ++++ K+ V+ +G E L +I+ L + +
Sbjct: 82 -EDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVML-----KSDASP 134
Query: 273 KGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTV-EVEIDRGIIQEPVR 331
+R L + + LV I G+++ ++ + + +C C +T+ + + G+ E
Sbjct: 135 SSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGL--EGYA 192
Query: 332 CPRVVCNSPNS---------MVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYD 382
PR CN+ + ++ ++C D Q +KLQE PD VP G+ P + L
Sbjct: 193 LPRK-CNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDR 251
Query: 383 ELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTV 442
L D G+R+ + GI+ ++K T +DRVGV +
Sbjct: 252 YLCDKVVPGNRVTIMGIY------------SIKKFGLT-------TSRGRDRVGVGIRSS 292
Query: 443 EQQLLQNQIDNVEEIRT----LSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKG 498
++L Q+D R+ +S ++ + A +VY+V+S+SIAPSI+ D+KK
Sbjct: 293 YIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKA 352
Query: 499 ILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAV 558
I LFGG+ K G RGDIN+L+ GDP T+KSQ+L++V K +P GVYTSGKGSSA
Sbjct: 353 IACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAA 412
Query: 559 GLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKA 618
GLTA V RD ++ ++E GA+VL+DGGV CIDEFDKM ++ R +HE MEQQTISIAKA
Sbjct: 413 GLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKA 472
Query: 619 GIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRE 678
GI TTLN+R S+LA+AN + R++ +NID P +LSRFD++++V D+ NE D
Sbjct: 473 GITTTLNSRCSVLAAANSVFGRWD-ETKGEDNIDFMPTILSRFDMIFIVKDEHNEVRDVM 531
Query: 679 LAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRK 738
LAKH+ +L++ + + + + L +I Y + P ++ A +L Y+ MR
Sbjct: 532 LAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRT 591
Query: 739 MGDDSRS--DEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYA 796
+R I T RQLE+++R++EA +KM+L DVEEA+RL + + D A
Sbjct: 592 GPVSTRGTVTASSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAA 651
>Hs4758706 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 892
Score = 314 bits (805), Expect = 3e-85
Identities = 197/595 (33%), Positives = 316/595 (53%), Gaps = 60/595 (10%)
Query: 187 YVNQLNQMRQLGTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLAL 246
+ +++ M + +L ++ +L A +H F + P E++ I D+ + V LA+
Sbjct: 204 FKERISDMCKENRESLVVNYEDLAAREHVLAYF--LPEAPAELLQIFDEAALE--VVLAM 259
Query: 247 DNGLESYLNEIESKLFKVRPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVA 306
+ N I VR ++ + +R L +++L+ G+V T ++P +S+
Sbjct: 260 YPKYDRITNHIH-----VRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMV 314
Query: 307 FFKCNVCNHTVEVEIDRGIIQ-EPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQETPD 365
+ CN CN + + +P CP C S + +Q+ Q I++QE+P
Sbjct: 315 KYNCNKCNFVLGPFCQSQNQEVKPGSCPE--CQSAGPFEVNMEETIYQNYQRIRIQESPG 372
Query: 366 LVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSL--YKTYID 423
V + P S + +LVDSC AGD IE++GI+ N +L + + +
Sbjct: 373 KVAARRLPRSKDAILLADLVDSCNAGDEIELTGIYH------NNYDGSLNTANGFPVFAT 426
Query: 424 VVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSR 483
V+ VAK DN + L+ ED++ I ++ + + +
Sbjct: 427 VILANHVAKK------------------DNKVAVGELTDEDVKMITSLSKDQQIGEKIFA 468
Query: 484 SIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKI 543
SIAPSIY +D+K+G L LFGG K + RGDIN+LLCGDP T+KSQ L+Y+ K+
Sbjct: 469 SIAPSIYGHEDIKRGPALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKV 528
Query: 544 APRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSV 603
+ R ++T+G+G+SAV +TAYV R +++ LE+GALVL+D GVC IDEFDKMND R+
Sbjct: 529 SSRAIFTTGQGASAVAVTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTS 588
Query: 604 LHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDL 663
+HE MEQQ+ISI+KAGI+T+L AR +++A+ANPI RY+P+L +EN+DL P++SRFD+
Sbjct: 589 IHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDI 648
Query: 664 VYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDI------------------LPVEF 705
+ +V D V+ D LA+ + ++ P + + + LP E
Sbjct: 649 LCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEV 708
Query: 706 LTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESM 760
L YI YAK+ +HP + + + ++ + Y +RK + S I T R +ESM
Sbjct: 709 LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGS----IPITVRHIESM 759
>ECU04g0850 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 780
Score = 311 bits (796), Expect = 4e-84
Identities = 195/632 (30%), Positives = 337/632 (52%), Gaps = 54/632 (8%)
Query: 168 KELDDQEIFINETTDQELYYVNQLN------QMRQLGTSNL-NLDIRNLLAYKHTEKLFH 220
K+ +Q+ F + + + + N+ ++RQ+ T NL ++++ L + + L
Sbjct: 95 KDFFEQDFFRAKVVRKFIRFFNEFGNKKYAKRIRQMCTENLESIEVSYLDIEEESIDLLR 154
Query: 221 QILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNVETKKGMRELNP 280
+ + + I +MD+ + D +V + N + I+ K+ R ++ +R L
Sbjct: 155 LLNQHAEMTIEVMDRALSD-VVRMHFPN-----YHMIKPKVHS-RVVDLPVCDSVRSLRN 207
Query: 281 NDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVCNSP 340
+ KLV + G+V R + + P S+ F C C + +P C C S
Sbjct: 208 RHLGKLVRVSGVVTRRSGVFPLYSIVKFSCLKCRSVFGPFVASSF--KPTHC--FECQSK 263
Query: 341 NSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIF 400
+ + ++D Q + +QE P VP G P S + ++ +L+D + G+ +EV+G++
Sbjct: 264 GPFTVNTSETVYKDFQKLTIQEIPGSVPPGSLPRSKEVLLFYDLIDCAKPGEEVEVTGVY 323
Query: 401 RS-IPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRT 459
++ + N +++ + + V+ V K ++
Sbjct: 324 KNNFNVSLN-----IRNGFPVFFTVIEASSVVKRAGKIE--------------------- 357
Query: 460 LSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRG 519
++ +D+R IK+ R ++ ++ SIAPS+Y +VK+ I L + GG + R RG
Sbjct: 358 MTDDDVREIKKMGRHPEIKRIVINSIAPSVYGHAEVKRAIALAMLGGVARE-STSHRIRG 416
Query: 520 DINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGA 579
DIN+LL GDP +KSQ L+YV + R V +G+G+S+VGLTA V +D K+ LE GA
Sbjct: 417 DINVLLLGDPGMAKSQFLRYVESTSHRAVLATGQGASSVGLTASVRKDPVVKEWTLEGGA 476
Query: 580 LVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINS 639
LVL+D G+C IDEFDKMN++ R+ +HE MEQQ+ISI+KAGI+ TL+AR S++A+ANP+
Sbjct: 477 LVLADKGICLIDEFDKMNEHDRTSIHEAMEQQSISISKAGIVATLHARCSVIAAANPMRG 536
Query: 640 RYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYL--EDRPDSVS- 696
RYN +L +N++L P++SRFD++ +V D ++ D + AK + + E++PD
Sbjct: 537 RYNGSLTFAQNVNLSDPIISRFDILCVVKDAIDAGEDEKTAKFVIESHEGGEEKPDGFDP 596
Query: 697 QGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQ 756
+ ++ E L YI YA+ N+ P + ++ Y+ +RK S + T R
Sbjct: 597 KRMMMGHELLRKYILYARTNVVPAFNDVDMEKISSLYLELRK-----ESLPSGLPVTVRH 651
Query: 757 LESMIRLSEAHAKMRLSERVELEDVEEAVRLI 788
+ES++R+SEA AKMRLS V +ED++EA+ ++
Sbjct: 652 VESIVRISEAFAKMRLSRVVSVEDIDEAISVV 683
>ECU09g1360 [L] KOG0482 DNA replication licensing factor MCM7 component
Length = 694
Score = 310 bits (793), Expect = 8e-84
Identities = 204/582 (35%), Positives = 306/582 (52%), Gaps = 57/582 (9%)
Query: 275 MRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPR 334
+R L I LV + G+V + + + P + VA + C C E+D + C
Sbjct: 147 VRGLKSMHIGSLVRVSGVVTKVSQVKPSIRVATYVCEGCGAETYQEVDGDVFDLLEECGS 206
Query: 335 VVCNSPN---SMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAG 391
C N ++VLV F Q + +QE +P G P ++ Y + + CR G
Sbjct: 207 EKCRIRNVRGTLVLVTRGSKFIKHQTVYMQELTGDIPRGCIPRTLVAECYSSMAEKCRPG 266
Query: 392 DRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQI 451
D + V G+F P K +A L Y+ +I+K+ G
Sbjct: 267 DVVVVGGVFMPKPYHGIKKLKA-GLLADIYLHATNIEKIG---AGAPKGN---------- 312
Query: 452 DNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTF 511
EE++ E + RSIAP I+ ++D+KK +LL L G +
Sbjct: 313 ---EEVKAYPVEQ----------------MVRSIAPEIFGMEDIKKILLLMLIGAPGRVR 353
Query: 512 KKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTK 571
+ G + RGDIN+LL GDP +KSQ+L+ KI RGVYT+GKGSS VGLTA V++D T
Sbjct: 354 EDGMKIRGDINVLLVGDPGIAKSQLLKTCVKIGRRGVYTTGKGSSGVGLTASVSKDPITG 413
Query: 572 QLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSIL 631
++VLE GALVL+DGG+CCIDE DKMN+ R +HEVMEQQ++SI+KAGI T+LNAR +L
Sbjct: 414 EMVLEGGALVLADGGICCIDELDKMNEVDRVSIHEVMEQQSVSISKAGINTSLNARCCVL 473
Query: 632 ASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDR 691
+ANP+ +Y+ + NI LP LLSRFD+V ++ D+ N D LA H+TS++L +
Sbjct: 474 GAANPVKGKYDTRQSIEHNIGLPCALLSRFDVVAILRDEPNLEKDESLANHITSIHLHEE 533
Query: 692 PDSVSQGDILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRIT 751
P+S+ P + + I+ AK+ I+PV+ +L AYV RK +
Sbjct: 534 PESI------PYDKIRLIIDEAKR-INPVLPSHLSGKLTDAYVKARK---------ESPY 577
Query: 752 ATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDMNLVQT 811
T R L S+IRLS AH ++RLS V +DV EA+RL++ P+ + +++ +
Sbjct: 578 VTPRYLLSLIRLSLAHCRLRLSTDVNEDDVNEALRLMEVT---RIPVPRKRREEVSSKRA 634
Query: 812 GKSVVQRKLLEDLAREILKI--LTERTTDTISFNELSKLINE 851
+++ E+ R +K+ L E T D S +E+ +I++
Sbjct: 635 IYNLILSLAGEEGGRRCVKLAHLWEATKDKYSVSEVEDVISD 676
>CE08392 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 812
Score = 308 bits (790), Expect = 2e-83
Identities = 213/678 (31%), Positives = 339/678 (49%), Gaps = 99/678 (14%)
Query: 167 RKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNL--NLD-IRNLLAYKHTEKLFHQIL 223
++E+ +Q + + +Y ++ +M G S L NLD IR +L
Sbjct: 18 KQEITEQYLNFLDNQADTFHYRQKIVKMMNDGESRLVMNLDEIREIL------------- 64
Query: 224 YYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRPYNV--ETKKGMRELNPN 281
P+ ++ Q+V + L + L+ +N + + ++V E G R +NP
Sbjct: 65 --PERAEGLLTQSVLEMN---CLQSALQMAINRSDVQAVVKTGFHVGFEGTFGERHVNPR 119
Query: 282 DIDK-----LVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEI-DRGIIQEPVRCPRV 335
+ LV +G+V + + + + + C N +E + D ++ V
Sbjct: 120 TLKSSYLGNLVCCEGIVTKCSTVRQKLLTSVHYCPATNKVLEKKFADFTMLDTAVTNNNY 179
Query: 336 VCNSPNSMVLV--HNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYD-ELVDSCRAGD 392
N L ++D Q +QE P+ P GQ P +V CV D +L D + GD
Sbjct: 180 PTEDENKNPLETEFGHSVYKDHQTFTIQELPESAPAGQLPRAVD-CVADLDLADRVKPGD 238
Query: 393 RIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQID 452
R+ + G+FR +P N + +++ I + HIQ ++K
Sbjct: 239 RVRIIGVFRVLP---NKQNGVSSGSFRSIIIINHIQMLSK-------------------- 275
Query: 453 NVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFK 512
E I +D++ +++ ++ + +++L+RS+APSI ++ KK +L L GG K
Sbjct: 276 --EVIPNFEPQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILN 333
Query: 513 KGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQ 572
G R RGDIN+LL GDPS +KSQ+L+YV ++APR + T+G+GSS VGLTA VT D D+ +
Sbjct: 334 NGSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTDPDSGE 393
Query: 573 LVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILA 632
LE+GA+VL+D GV CIDEFDKM+D R+ +HEVMEQ ++I+KAGI LNAR S+LA
Sbjct: 394 RRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLA 453
Query: 633 SANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRP 692
+ANP+ RYNP ENI + LLSRFDL++++LD+ + D +A+H+ L+ R
Sbjct: 454 AANPVYGRYNPFKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTY-RT 512
Query: 693 DSVSQGDILP---------------------------------------VEFLTAYINYA 713
+ G +LP ++F+ YI+ A
Sbjct: 513 QGEADGTVLPMGGGVETISTINMETKKASSSIYEENTQWAGIQDTKILTMDFMRKYIHLA 572
Query: 714 KQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLS 773
+ ++ P +T+ A + Y +R E+ + T RQLE++IRLS A AK R S
Sbjct: 573 R-SVQPKLTDEATEYISEVYADIRSFDITKTDQERTMPVTARQLETLIRLSTAIAKARFS 631
Query: 774 ERVELEDVEEAVRLIKSA 791
++VE ED E+A L+ A
Sbjct: 632 KKVEREDTEKAYNLLHFA 649
>YEL032w [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 971
Score = 302 bits (774), Expect = 1e-81
Identities = 211/586 (36%), Positives = 313/586 (53%), Gaps = 86/586 (14%)
Query: 276 RELNPNDIDKLVSIKGLVLRSTPIIPDM--SVAFFKCNVCNHTVEVEIDRGIIQEPVRCP 333
R L ++KLVS++G+V +++ + P + SV + H + + + P
Sbjct: 169 RTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTP 228
Query: 334 RVVCNSP---NSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRA 390
+ N + + TF D Q I +QE P++ P GQ P S+ + + D+LVD +
Sbjct: 229 AIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKP 288
Query: 391 GDRIEVSGIFRSIPIRSNPKQRALKSL-YKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQN 449
GDR+ V G+F+S+ + + + +KT I +G +TV L
Sbjct: 289 GDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLI------------LG---NTVYP--LHA 331
Query: 450 QIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANK 509
+ V + L+ DIR I + +++ D++D+LS+S+APSIY D +KK ILL L GG K
Sbjct: 332 RSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEK 391
Query: 510 TFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVD 569
+ G RGDINIL+ GDPST+KSQ+L++V A + T+G+GSS VGLTA VT D +
Sbjct: 392 NLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRE 451
Query: 570 TKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTS 629
T + LE+GA+VL+D GV CIDEFDKM D R +HEVMEQQT++IAKAGI TTLNAR S
Sbjct: 452 TGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCS 511
Query: 630 ILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKH------- 682
++A+ANP+ +Y+ N +NI LP LLSRFDL+++V D +NE DR +++H
Sbjct: 512 VIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRY 571
Query: 683 LTSLYLEDRPD------SVSQG---DILPVEFLTAYI----------NYAKQNIHPVITE 723
L YLE P S++ G DI P E + ++ + +P++
Sbjct: 572 LPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQA 631
Query: 724 SAK----------TEL--------VRAYVGMRKMG-----------------DDSRSDE- 747
AK TE+ +R YV K D R+D+
Sbjct: 632 GAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDN 691
Query: 748 -KRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAI 792
K+ T R LE++IRL+ AHAK+RLS+ V D + A L++ A+
Sbjct: 692 TKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFAL 737
>ECU08g0290 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 687
Score = 299 bits (765), Expect = 1e-80
Identities = 179/439 (40%), Positives = 261/439 (58%), Gaps = 38/439 (8%)
Query: 354 DRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRA 413
D Q + LQE P+ P GQ P SV + + +LVD + GDR ++ GI++S+ + +
Sbjct: 178 DYQTVVLQEMPEKAPPGQLPRSVEVILSFDLVDGLKPGDRAKIYGIYKSLCFGN----QQ 233
Query: 414 LKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETAR 473
S ++T + +I+K ++ V V+ ++L +Q+ N+ +
Sbjct: 234 FPSRFRTVVIANNIEKAEEEEVEVEPGVEFERL--SQMKNMHHL---------------- 275
Query: 474 RSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSK 533
IAPSI+ D VK+ I L L GG + G + RGDINILL GDPST+K
Sbjct: 276 -----------IAPSIFGHDIVKRSIALLLVGGNEVVMRNGSKIRGDINILLVGDPSTAK 324
Query: 534 SQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEF 593
SQ+L+YV A + T+GKGSS VGLTA V D DT + LE+GA+VL+D GV CIDEF
Sbjct: 325 SQLLRYVLNAAQLSIATTGKGSSGVGLTAAVVLDKDTGEKRLEAGAMVLADRGVVCIDEF 384
Query: 594 DKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDL 653
DKM+D R +HEVMEQQT++IAKAGI TTLNAR S+LA+ANPI +Y + P +N+ L
Sbjct: 385 DKMSDGDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVLAAANPIWGQYKESRPPQDNVRL 444
Query: 654 PPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDILPVEFLTAYINYA 713
P LL+RFDL+++ LDK N D+ ++ H+ +++ + +G + E AYI Y
Sbjct: 445 PESLLTRFDLIFVTLDKSNTDIDQLVSGHVLRMHMLTQ-GYEEEGMGVKQEVFRAYIRYC 503
Query: 714 KQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLS 773
+Q PV++ A + R Y +R+ D E+ ++ T R LE+MIRL+ A+AK+RLS
Sbjct: 504 RQK-KPVLSREAAGLIAREYTSLRQSKD---RKEQIVSITPRMLETMIRLATANAKLRLS 559
Query: 774 ERVELEDVEEAVRLIKSAI 792
+ VE +D E AV L+K ++
Sbjct: 560 DVVEYDDAECAVNLVKDSL 578
>7290573 [L] KOG0479 DNA replication licensing factor MCM3 component
Length = 819
Score = 295 bits (754), Expect = 3e-79
Identities = 214/691 (30%), Positives = 330/691 (46%), Gaps = 107/691 (15%)
Query: 157 EFLMSFKLKYRKELDDQEIFINETTDQELYYVNQLNQMRQLGTSNLNLDIRNLLAYKHTE 216
+F+ + +Y LDD+E DQ +Y + M + L +++ +L
Sbjct: 7 QFIKDIQREYVDFLDDEE-------DQGIY-AGHVKDMIAEKSKRLIVNVNDLKRKN--- 55
Query: 217 KLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEIESKLFKVRP---YNVETKK 273
PQ + ++ + LA L+ Y + ++ K+ E
Sbjct: 56 ---------PQRALGLLSNAADE---QLAFGRALKEYASTVDPGYAKMHEDLFVGFEGCF 103
Query: 274 GMRELNPNDIDKL-----VSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQE 328
G R + P + + V ++G+V + + I P + + C +E + E
Sbjct: 104 GNRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTSFE 163
Query: 329 PVRCPRVVCNSP---NSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELV 385
V N + + ++D Q + +QE P+ P GQ P SV + D+LV
Sbjct: 164 AVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLV 223
Query: 386 DSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQ 445
D C+ GDR+++ G +R +P + R G + T
Sbjct: 224 DRCKPGDRVQIVGSYRCLPGK---------------------------RGGYTSGTFRTV 256
Query: 446 LLQNQID--NVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQL 503
LL N I + E +S EDI K+ A+ +D++++LS+S+APSI+ VK+ IL L
Sbjct: 257 LLANNISLLSKESNLDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLL 316
Query: 504 FGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAY 563
GG K G R RGDIN+LL GDPS +KSQ+L+YV APR + T+G+GSS VGLTA
Sbjct: 317 LGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAA 376
Query: 564 VTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITT 623
VT D +T + LE+GA+VL+D GV CIDEFDKM+D R+ +HEVMEQ ++I+KAGI +
Sbjct: 377 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAS 436
Query: 624 LNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHL 683
LNAR S+LA+ANP+ RY+ ENI L LLSRFDL++++LD ++ D+ ++ H+
Sbjct: 437 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHV 496
Query: 684 TSLYLEDRP---------------DSVS----------------------------QGDI 700
++ P DS+S I
Sbjct: 497 VRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHEKI 556
Query: 701 LPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESM 760
L VEF+ YI+ AK + P + E A + Y +R + T R LE++
Sbjct: 557 LSVEFMRKYIHIAK-CMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETL 615
Query: 761 IRLSEAHAKMRLSERVELEDVEEAVRLIKSA 791
IRLS AHA+ R+S+ V ++D A+ L++ A
Sbjct: 616 IRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
>Hs19923727 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 840
Score = 284 bits (726), Expect = 5e-76
Identities = 193/626 (30%), Positives = 307/626 (48%), Gaps = 55/626 (8%)
Query: 265 RPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRG 324
R YN E ++ + N K ++++G V+R + I P + F C C + G
Sbjct: 197 RVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDG 256
Query: 325 IIQEPVRCPRVVCNSPNSMVLVHNRCTF-QDRQVIKLQE--TPDLVPDGQTPHSVSLCVY 381
P +CP VC + L + T D Q IK+QE + D G+ P ++ +
Sbjct: 257 KYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316
Query: 382 DELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTST 441
+LVDSC GD + ++GI + + + K ++ YI+ I +
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376
Query: 442 VEQQLLQNQIDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILL 501
+ +L S +D+ I+E +++ ++ S+ P I+ + VK G+ L
Sbjct: 377 CKHGMLME----------FSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLAL 426
Query: 502 QLFGGANKTFKKGGRY--RGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVG 559
LFGG+ K R RGD +IL+ GDP KSQ+LQ +APRGVY G ++ G
Sbjct: 427 ALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSG 486
Query: 560 LTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAG 619
LT +++D + LE+GALVL D G+C IDEFDKM + +++L E MEQQ+IS+AKAG
Sbjct: 487 LTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALL-EAMEQQSISLAKAG 545
Query: 620 IITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDREL 679
++ +L ARTSI+A+ANP+ YN V+EN+ + LLSRFDLV+++LD NE D L
Sbjct: 546 VVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLL 605
Query: 680 AKHLTSL---------------------------YLEDRPDS----VSQG---DILPVEF 705
++H+ ++ + ++P S V G D +P +
Sbjct: 606 SEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQL 665
Query: 706 LTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSE 765
L YI YA+Q ++P ++ A L Y+ +RK S TTRQLES+IRL+E
Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSS----PITTRQLESLIRLTE 721
Query: 766 AHAKMRLSERVELEDVEEAVRLIKSAIKDYATDPKTGKIDMNLVQTGKSVVQRKLLEDLA 825
A A++ L E ED E+ V ++K ++ +D + G +D Q G + R +
Sbjct: 722 ARARLELREEATKEDAEDIVEIMKYSMLGTYSD-EFGNLDFERSQHGSGMSNRSTAKRFI 780
Query: 826 REILKILTERTTDTISFNELSKLINE 851
+ + + F++L ++ E
Sbjct: 781 SALNNVAERTYNNIFQFHQLRQIAKE 806
>At3g09660 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 777
Score = 279 bits (714), Expect = 1e-74
Identities = 188/626 (30%), Positives = 318/626 (50%), Gaps = 40/626 (6%)
Query: 198 GTSNLNLDIRNLLAYKHTEKLFHQILYYPQEIIAIMDQTVKDCMVSLALDNGLESYLNEI 257
G+ +L+LD++ E F + P+ +I M+ V + N E+ +
Sbjct: 73 GSFSLSLDLQQFKKISDIENFFINLEDNPKGVIPCMNAAVHKVLFDQWETNEFENVMK-- 130
Query: 258 ESKLFKVRPYNV-ETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHT 316
VR +N E+ ++ L I KLV++ G V++ + + P ++ F C C
Sbjct: 131 ----INVRLHNYPESSISLKNLRAAYIGKLVTVHGTVVKVSTVKPLVTQMAFDCGKCKTG 186
Query: 317 VEVEIDRGIIQEPVRCPRVVCNSPNSMVLVHNRCTFQDRQVIKLQET--PDLVPDGQTPH 374
+ E G P++C C S + + + D Q I++QE P+ +G+ P
Sbjct: 187 ITREFTDGKFSPPLKCDSHGCKS-KTFTPIRSSAQTIDFQKIRVQELQKPEDHEEGRVPR 245
Query: 375 SVSLCVYDELVDSCRAGDRIEVSGIFRSI----PIRSNPKQRALKSLYKTYIDVVHIQKV 430
+V + ++LVD C GD + V+GI I I + + Y +I+ V ++
Sbjct: 246 TVECELMEDLVDICIPGDVVTVTGIIGVINNYMDIGGGKSKTKNQGFYYLFIEAVSVKNT 305
Query: 431 AKDRVGVDTSTVEQQLLQNQIDNVEEIRTLSSEDIRRIKETARR--SDVYDVLSRSIAPS 488
+ ++ E Q +V ++ + S D+ I + SD + + S+ PS
Sbjct: 306 KRQSAFENS---EDSSSSAQTADVGDLYSFSQRDLEFIVKFKEEYGSDTFRRILHSVCPS 362
Query: 489 IYELDDVKKGILLQLFGGANKTFKKGGRY--RGDINILLCGDPSTSKSQILQYVHKIAPR 546
IY + VK GI L LFGG K + RGDI++++ GDP KSQ+LQ I+PR
Sbjct: 363 IYGHEIVKAGITLSLFGGVRKHSMDRNKVPVRGDIHVIIVGDPGLGKSQLLQAAAAISPR 422
Query: 547 GVYTSGKGSSAVGLTAYVTRDVDTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHE 606
G+Y G ++ GLT V +D T E+GA+VL+DGG+CCIDEFDKM +++L E
Sbjct: 423 GIYVCGNATTRAGLTVAVVKDSMTNDYAFEAGAMVLADGGLCCIDEFDKMTTEHQALL-E 481
Query: 607 VMEQQTISIAKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYL 666
MEQQ +S+AKAG++ +L+ARTS++A+ANP+ YN V EN+ + LLSRFDLV++
Sbjct: 482 AMEQQCVSVAKAGLVASLSARTSVIAAANPVGGHYNRAKTVNENLKMSAALLSRFDLVFI 541
Query: 667 VLDKVNEASDRELAKHLTSLYLEDRPDSVSQGDIL-------PVEFLTAYINYAKQ---N 716
+LDK +E D+++++H+ S + + Q IL + +T ++ + N
Sbjct: 542 LLDKPDELLDKQVSEHIMSHHRMLGMQTCMQKGILYFQDCGWTLRKMTTFLRFLANCLGN 601
Query: 717 IHP----VITESAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRL 772
I P ++++ A + + Y+ +R D + T RQLES++RL++A A++ L
Sbjct: 602 IFPMHGILMSKDAGEIIQKFYLKLR----DHNTSADSTPITARQLESLVRLAQARARVDL 657
Query: 773 SERVELEDVEEAVRLIKSAIKDYATD 798
E + ++D + V ++K ++ D D
Sbjct: 658 REEITVQDAMDVVEIMKESLYDKLID 683
>ECU11g0800 [L] KOG0480 DNA replication licensing factor MCM6 component
Length = 681
Score = 227 bits (579), Expect = 5e-59
Identities = 167/540 (30%), Positives = 273/540 (49%), Gaps = 66/540 (12%)
Query: 274 GMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCP 333
G +++ ++ KLV + G V R + FF+C+ C TV V++ + + P C
Sbjct: 107 GFGDIDRANLGKLVFMTGTVCRVGFRRVVSTKMFFECSKCGETVCVDVKNNVYRPPRTC- 165
Query: 334 RVVCNSPN-SMVLVHNRCTFQDRQVIKLQET-PDLVPDGQ-TPHSVSLCVYDELVDSCRA 390
R CNS + + V H ++D Q IK+QE DG P +V +YDE +
Sbjct: 166 RGSCNSRSFAPVRNHPEVEYRDVQEIKIQELYGGSEGDGNGIPKAVDCILYDEFAGTLAP 225
Query: 391 GDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQ 450
GD +E+ G+ + + ++ +LYK VHI + Q+++N+
Sbjct: 226 GDIVEIVGVL-GVELEND-------NLYKL---TVHINNL--------------QIVKNK 260
Query: 451 IDNVEEIRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKT 510
VE++ S D ++ A + L S+ ++Y + +K G++L LFGG T
Sbjct: 261 NFFVEDVE-YQSRDFAEFRKIAGAGNTLASLVCSLYSAVYGNELIKVGLVLSLFGG---T 316
Query: 511 FKKGGRY--RGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDV 568
K G++ R + ++L+ GDP KS++L I P+ Y SG ++ GLT +T D
Sbjct: 317 KKSAGQHSIRSETHVLIVGDPGLGKSRLLLSTCGILPKSSYVSGSFTTTAGLTVSLTHDP 376
Query: 569 DTKQLVLESGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNART 628
+ + + ++GALV++D G+CC+DEFDK++D+ + L E ME Q +SIAK G+I ++ R
Sbjct: 377 VSGEYMADAGALVVADNGICCLDEFDKIDDH--AALFEAMEDQKVSIAKGGVICSVPTRA 434
Query: 629 SILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNE-----ASDRELAKHL 683
+++A+ NP + ++ + ENI P LLSRFDL++L+LD ++E S + L K
Sbjct: 435 TVIAATNPRHGHFDRGKTMAENIRFDPGLLSRFDLIFLLLDDLSEKESYMISGQILKKRR 494
Query: 684 TSLYLEDRPDSV--------------SQGDILPVEFLTAYINYAKQNIHPVITESAKTEL 729
T E D V S G + P++ + YI+YA+ N+ PV+++SA +
Sbjct: 495 TLSPGEGGFDDVVETVRRDMFVEDIRSGGCVYPMDIVRKYISYARANVFPVLSKSASEAI 554
Query: 730 VRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLSEAHAKMRLSERVELEDVEEAVRLIK 789
YVGMR G +TR LES++RL+EA AK+ L D + L K
Sbjct: 555 KEYYVGMRSRGG----------VSTRDLESLVRLTEARAKVELRSIATKADAMFCIELHK 604
>ECU07g0490 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 563
Score = 184 bits (467), Expect = 5e-46
Identities = 152/517 (29%), Positives = 253/517 (48%), Gaps = 48/517 (9%)
Query: 279 NPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRGIIQEPVRCPRVVCN 338
N +I+++V++ G V+R+ + + C CN + R R++C
Sbjct: 54 NSKNINRIVTVNGTVIRAYETLIRNVTSELVCLKCN------VRAYRCSAGKRKDRMLCE 107
Query: 339 SPNSMVLVHNRCTFQ--DRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEV 396
S S +L RC Q I++Q D+ ++ + + ++L GD + +
Sbjct: 108 SCGSSLLRDRRCFGGAIPSQKIRIQ---DIGNRSSMSETLEVVLEEDLAGKFLPGDNLLI 164
Query: 397 SGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEE 456
+G ++ IR P + + Y+ + + K ++ +G + ++D +
Sbjct: 165 TG---TVLIRWRPFKVGEQMASSIYMHALAVHKQDEESMGDSFG----RTFLGRLDGMGW 217
Query: 457 IRTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGR 516
RR+ +L S A I L++VK G+LL L G++ +K G
Sbjct: 218 FE-------RRL-----------LLVNSFAEEIQGLENVKLGLLLALVSGSHGADQKSGT 259
Query: 517 YRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLE 576
R + +ILL GD T KS +L+ ++ V T+G G++ GLT R ++ VLE
Sbjct: 260 -RSNSHILLVGDSGTGKSHLLKTCSRLLSPAVLTNGVGTTQAGLTTCAVRQ--GREWVLE 316
Query: 577 SGALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAKAGIITTLNARTSILASANP 636
+GALVL+D G+CCIDEF+K+ N ++ L E MEQQT+SIAKAGI+++LN R S++A+ N
Sbjct: 317 AGALVLADTGLCCIDEFNKLKVNEKNGLLEAMEQQTLSIAKAGIVSSLNTRCSVIAAIN- 375
Query: 637 INSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEASDRELAKHLTSLYLEDRPDSVS 696
+Y+ N ++ENI + PL+SRFDL++ + D + SD + + E
Sbjct: 376 TRHKYSFNKSISENIMVATPLISRFDLIFGLFDDRDGRSDLLIVDKILGRRPETGLTDKK 435
Query: 697 QGDIL-PVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMRKMGDDSRSDEKRITATTR 755
QG + L YI A++ VI + L+ Y RK + + T R
Sbjct: 436 QGSVCWDHNILRNYIGVARKR-RAVIPDDLNAVLLSYYHHRRKAEGANEFN------TVR 488
Query: 756 QLESMIRLSEAHAKMRLSERVELEDVEEAVRLIKSAI 792
LES+ RL+EAH+K+ SER E DV A+ L+++A+
Sbjct: 489 MLESLARLTEAHSKLLNSERAEEGDVYSAIILLETAL 525
>At2g14050 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 610
Score = 166 bits (421), Expect = 1e-40
Identities = 112/339 (33%), Positives = 178/339 (52%), Gaps = 30/339 (8%)
Query: 286 LVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTV----EVEIDRGIIQEPVRCPRV---VCN 338
L+ +KG V+RS + ++C C H E+E I++ P CP C
Sbjct: 138 LMMLKGTVIRSGAVKMYEGEKMYRCRKCKHMFPIFPELESINSIVKPPF-CPSQRSKACE 196
Query: 339 SPNSMVLVHNRCTFQDRQVIKLQETPDLVPDGQTPHSVSLCVYDELVDSCRAGDRIEVSG 398
N V + T D Q IK+QE ++ G P S+ + + D+LVD+ +AGD + VSG
Sbjct: 197 GTN-FDPVDDTVTRHDYQEIKIQENTQVLGVGVIPRSILVVLKDDLVDNVKAGDDVVVSG 255
Query: 399 IFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVDTSTVEQQLLQNQIDNVEEIR 458
I S + + + ++ + + H+++ + + +D S D +E+ +
Sbjct: 256 ILTS---KWSHDLKDVRCDLEPMLIANHVRRTNELKSEIDISD----------DLIEKFK 302
Query: 459 TLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYR 518
S ++T + + + R I P ++ L VK + L L GG G + R
Sbjct: 303 NFWSH----FRDTPLKGR--NAILRGICPQVFGLFTVKLAVALTLIGGVQHVDASGTKVR 356
Query: 519 GDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSSAVGLTAYVTRDVDTKQLVLESG 578
G+ ++LL GDP T KSQ L++ K++ R V T+G GS++ GLT VT D + +LE+G
Sbjct: 357 GESHLLLIGDPGTGKSQFLKFAAKLSNRAVITTGLGSTSAGLT--VTAVKDGGEWMLEAG 414
Query: 579 ALVLSDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISIAK 617
ALVL+DGG+CCIDEFD M ++ R+ +HE MEQQ+IS+AK
Sbjct: 415 ALVLADGGLCCIDEFDSMREHDRATIHEAMEQQSISVAK 453
>7300061 [L] KOG0478 DNA replication licensing factor MCM4 component
Length = 755
Score = 150 bits (379), Expect = 8e-36
Identities = 139/540 (25%), Positives = 241/540 (43%), Gaps = 103/540 (19%)
Query: 265 RPYNVETKKGMRELNPNDIDKLVSIKGLVLRSTPIIPDMSVAFFKCNVCNHTVEVEIDRG 324
RP + + + ++ + +D L SI+G V ++ F+C+ C + + RG
Sbjct: 236 RPDDFVPVESIEGISHSRVDTLFSIRGFVSNVGEPSYSLTWQAFRCSRCQMEIAMR-QRG 294
Query: 325 IIQ-EPVRCPRVVCNSPNSMVLVHNR--CTFQDRQVIKLQETP-DLVPDGQT--PHSVSL 378
Q P +C R C + + V + + RQ+I+++E+ +LV D +T P + +
Sbjct: 295 TFQPRPYQCKRSECVARDEFVPLRSSPYTRLSIRQIIRVEESSLNLVHDFETSMPAEMDV 354
Query: 379 CVYDELVDSCRAGDRIEVSGIFRSIPIRSNPKQRALKSLYKTYIDVVHIQKVAKDRVGVD 438
+ +LVD+ R G + V+GI + +Q++ D D
Sbjct: 355 ELRHDLVDAVRVGQEVVVTGILK-------------------------LQELGDDTTTGD 389
Query: 439 TSTVEQQLLQN-QIDNVEEI-RTLSSEDIRRIKETARRSDVYDVLSRSIAPSIYELDDVK 496
TS Q L+ I + I R S D+ I + + +L +SIAP +Y + K
Sbjct: 390 TSNQMQPYLKAVSIRDASSIKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPK 449
Query: 497 KGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQYVHKIAPRGVYTSGKGSS 556
LL L GG KG IN+LL GDP K++ILQ +IA RG + SGK +
Sbjct: 450 AACLLSLLGG------KGAETEA-INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGA 502
Query: 557 AVGLTAYVTRDVDTKQLVLESGALVL-SDGGVCCIDEFDKMNDNTRSVLHEVMEQQTISI 615
VT K+ VL++G+L++ S GG C +D+ DK+ ++VL + ++ + +++
Sbjct: 503 QSAQQLGVTFAGRNKR-VLQAGSLMMASGGGHCTLDDVDKLASK-QAVLLQCLQSEEVNL 560
Query: 616 AKAGIITTLNARTSILASANPINSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVNEAS 675
AG + A+ S++A ANP +Y+ + +NI++ P LL F LVY++LDK +E
Sbjct: 561 PLAGAFASFPAQPSVIACANPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSE-R 619
Query: 676 DRELAKHLTSLY-----------------------------------------LEDRPDS 694
D L H+ +L+ ED DS
Sbjct: 620 DMSLTAHVRALHAGARKRARIAARYALKPKMSDSMCEVSLNVPAAGKDDDTIKTEDDNDS 679
Query: 695 VSQG-----------------DILPVEFLTAYINYAKQNIHPVITESAKTELVRAYVGMR 737
+ Q D+LP + +++YA+Q ++PV+ E A ++R ++ ++
Sbjct: 680 IMQQDYDLDKRLEVLPEEGDLDLLPPILIKKFLSYARQELNPVLNEDASNAVLRYFLELK 739
>Hs22056246 [L] KOG0477 DNA replication licensing factor MCM2 component
Length = 112
Score = 70.1 bits (170), Expect = 1e-11
Identities = 34/82 (41%), Positives = 51/82 (61%)
Query: 479 DVLSRSIAPSIYELDDVKKGILLQLFGGANKTFKKGGRYRGDINILLCGDPSTSKSQILQ 538
+V+ S+ P ++ + VK + + L GG +T G R RG+ ++LL GDP T KSQ L+
Sbjct: 25 NVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLK 84
Query: 539 YVHKIAPRGVYTSGKGSSAVGL 560
Y KI PR V T+G GS++ G+
Sbjct: 85 YAAKITPRSVLTTGIGSTSAGI 106
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.134 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,367,427
Number of Sequences: 60738
Number of extensions: 1880930
Number of successful extensions: 6416
Number of sequences better than 1.0e-05: 51
Number of HSP's better than 0.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 6152
Number of HSP's gapped (non-prelim): 84
length of query: 892
length of database: 30,389,216
effective HSP length: 115
effective length of query: 777
effective length of database: 23,404,346
effective search space: 18185176842
effective search space used: 18185176842
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)