ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4378 check: MH A KOG0063 RNA processing and modification RNAse L inhibitor, ABC superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4378 1546227 1544407 -607
(607 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR091c [A] KOG0063 RNAse L inhibitor ABC superfamily 1100 0.0
SPBC14F5.06 [A] KOG0063 RNAse L inhibitor ABC superfamily 874 0.0
Hs20532766 [A] KOG0063 RNAse L inhibitor ABC superfamily 848 0.0
Hs4506559 [A] KOG0063 RNAse L inhibitor ABC superfamily 834 0.0
7295014 [A] KOG0063 RNAse L inhibitor ABC superfamily 825 0.0
At4g19210 [A] KOG0063 RNAse L inhibitor ABC superfamily 819 0.0
At3g13640 [A] KOG0063 RNAse L inhibitor ABC superfamily 777 0.0
CE21713 [A] KOG0063 RNAse L inhibitor ABC superfamily 764 0.0
ECU11g1580 [A] KOG0063 RNAse L inhibitor ABC superfamily 659 0.0
Hs17452992 [A] KOG0063 RNAse L inhibitor ABC superfamily 353 3e-97
At4g30300 [A] KOG0063 RNAse L inhibitor ABC superfamily 175 2e-43
Hs16166977 [A] KOG0063 RNAse L inhibitor ABC superfamily 150 7e-36
Hs18600950_1 [A] KOG0063 RNAse L inhibitor ABC superfamily 105 2e-22
ECU05g1190 [EJ] KOG0062 ATPase component of ABC transporters wit... 69 2e-11
ECU03g0390 [Q] KOG0061 Transporter ABC superfamily (Breast cance... 67 1e-10
SPBC2G5.09c [Q] KOG0055 Multidrug/pheromone exporter ABC superfa... 64 5e-10
CE03260 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 61 4e-09
7295535 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 61 4e-09
At5g64840 [R] KOG0927 Predicted transporter (ABC superfamily) 61 6e-09
7297388 [Q] KOG0054 Multidrug resistance-associated protein/mito... 61 6e-09
CE16149 [U] KOG0058 Peptide exporter ABC superfamily 60 1e-08
Hs20143975 [Q] KOG0061 Transporter ABC superfamily (Breast cance... 59 2e-08
At3g62150 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 59 2e-08
At1g02530 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 59 2e-08
7303902 [Q] KOG0054 Multidrug resistance-associated protein/mito... 59 2e-08
7295830 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 59 2e-08
At2g36910 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 59 3e-08
Hs4501849 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 58 4e-08
CE05221 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 58 4e-08
7296045 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 58 4e-08
Hs4505769 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 58 5e-08
At1g02520 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 58 5e-08
7298089 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 58 5e-08
7293943 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 58 5e-08
Hs6005701 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 57 6e-08
Hs17865630 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 57 8e-08
7295821 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 57 8e-08
YFR009w [EJ] KOG0062 ATPase component of ABC transporters with d... 57 1e-07
Hs4557481 [Q] KOG0054 Multidrug resistance-associated protein/mi... 57 1e-07
Hs17933762 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 57 1e-07
At5g13580 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 57 1e-07
At5g09930 [R] KOG0927 Predicted transporter (ABC superfamily) 57 1e-07
CE15714 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 56 1e-07
7300555 [Q] KOG0054 Multidrug resistance-associated protein/mito... 56 1e-07
At2g39350 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 56 2e-07
Hs8051577 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 55 2e-07
Hs8051575 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 55 2e-07
At4g01830 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 55 2e-07
7295352 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 55 2e-07
CE20234 [IR] KOG0059 Lipid exporter ABCA1 and related proteins A... 55 3e-07
At5g14100 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 55 3e-07
At3g55090 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 55 3e-07
At2g47000 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 55 4e-07
7301180 [Q] KOG0054 Multidrug resistance-associated protein/mito... 55 4e-07
At5g61700 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 54 5e-07
At3g47750 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 54 5e-07
At3g28390 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 54 7e-07
Hs9506365 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 54 9e-07
Hs16156905 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 54 9e-07
Hs15451838 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 54 9e-07
CE23999 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 54 9e-07
CE23998 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 54 9e-07
CE03262 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 54 9e-07
At4g25450 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 54 9e-07
At3g55130 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 54 9e-07
At3g55110 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 54 9e-07
HsM4502457 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
Hs9961252 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
Hs9961250 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
Hs6995996 [Q] KOG0054 Multidrug resistance-associated protein/mi... 53 1e-06
Hs4505771 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
Hs21536378 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
At5g46540 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
At1g67940 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 1e-06
7301757 [Q] KOG0054 Multidrug resistance-associated protein/mito... 53 1e-06
7298517 [Q] KOG0054 Multidrug resistance-associated protein/mito... 53 1e-06
Hs22057784 [U] KOG0058 Peptide exporter ABC superfamily 53 2e-06
At2g39480 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 53 2e-06
Hs4557876 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 52 2e-06
CE03308 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 2e-06
At5g06530 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 52 2e-06
7303379 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 2e-06
7294698 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 52 2e-06
YKL209c [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 3e-06
SPCC663.03 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 3e-06
At3g47780 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 52 3e-06
CE06485 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 3e-06
At5g61740 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 52 3e-06
At4g33460 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 52 3e-06
At1g70610 [U] KOG0058 Peptide exporter ABC superfamily 52 3e-06
7291275 [Q] KOG0054 Multidrug resistance-associated protein/mito... 52 3e-06
At4g01820 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 51 4e-06
At2g41700 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 51 4e-06
At2g07680 [Q] KOG0054 Multidrug resistance-associated protein/mi... 51 4e-06
7299468 [Q] KOG0054 Multidrug resistance-associated protein/mito... 51 4e-06
7296258 [Q] KOG0061 Transporter ABC superfamily (Breast cancer r... 51 4e-06
Hs14550412 [IR] KOG0059 Lipid exporter ABCA1 and related protein... 51 6e-06
At3g55320 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 51 6e-06
At1g10680 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 51 6e-06
7295351 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 51 6e-06
YMR301c [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC supe... 50 8e-06
CE03261 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 50 8e-06
At3g55100 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 50 8e-06
Hs5031915 [Q] KOG0054 Multidrug resistance-associated protein/mi... 50 1e-05
CE24868 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 50 1e-05
CE03818 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily 50 1e-05
At3g47740 [IR] KOG0059 Lipid exporter ABCA1 and related proteins... 50 1e-05
At2g01320 [Q] KOG0061 Transporter ABC superfamily (Breast cancer... 50 1e-05
>YDR091c [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 608
Score = 1100 bits (2844), Expect = 0.0
Identities = 549/608 (90%), Positives = 578/608 (94%), Gaps = 1/608 (0%)
Query: 1 MSSKNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGI 60
MS KN+RIAIVS DKCKPKKCRQECKRSCPVVKTGKLCIEV PTSKIAFISE LCIGCGI
Sbjct: 1 MSDKNSRIAIVSADKCKPKKCRQECKRSCPVVKTGKLCIEVTPTSKIAFISEILCIGCGI 60
Query: 61 CVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
CVKKCPFDAIQIINLPTNL++ VTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL
Sbjct: 61 CVKKCPFDAIQIINLPTNLEAHVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
Query: 121 KILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
KILAGKQKPNLGRF+DPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI
Sbjct: 121 KILAGKQKPNLGRFDDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
Query: 181 KGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQEA 240
KGPVQKVGELLKLR+EKS +D KRYI ILQL+NVL R++ LSGGELQRFAIGMSCVQEA
Sbjct: 181 KGPVQKVGELLKLRMEKSPEDVKRYIKILQLENVLKRDIEKLSGGELQRFAIGMSCVQEA 240
Query: 241 DVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSV 300
DVYMFDEPSSYLDVKQRLNAA IIRSLL PT YVICVEHDLSVLDYLSDFVCIIYGVPSV
Sbjct: 241 DVYMFDEPSSYLDVKQRLNAAQIIRSLLAPTKYVICVEHDLSVLDYLSDFVCIIYGVPSV 300
Query: 301 YGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEAD-ASRAFTYPDMK 359
YGVVTLP+SVREGINIFLDGHIP+ENLRFRTEALQFR+ADA ++L+ D ASRAF+YP +K
Sbjct: 301 YGVVTLPASVREGINIFLDGHIPAENLRFRTEALQFRIADATEDLQNDSASRAFSYPSLK 360
Query: 360 RTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQ 419
+TQGDF L VE GEFSDS+ILVMMGENGTGKTTLIKLLAGA+ D+GQDIPKLNVSMKPQ
Sbjct: 361 KTQGDFVLNVEEGEFSDSEILVMMGENGTGKTTLIKLLAGALKPDEGQDIPKLNVSMKPQ 420
Query: 420 KIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVL 479
KIAPKF GTVRQLFFK+IR QFLNPQFQTDVVKPL+IDDIIDQEVQHLSGGELQRVAIVL
Sbjct: 421 KIAPKFPGTVRQLFFKKIRGQFLNPQFQTDVVKPLRIDDIIDQEVQHLSGGELQRVAIVL 480
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+LG+ ADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV
Sbjct: 481 ALGIPADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 540
Query: 540 FDGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGNY 599
F+GIPSK A ARAPESLLTGCN+FLKNLNVTFRRDP SFRPRINKLDSQMDKEQKSSGNY
Sbjct: 541 FEGIPSKNAHARAPESLLTGCNRFLKNLNVTFRRDPNSFRPRINKLDSQMDKEQKSSGNY 600
Query: 600 FFLDHNGV 607
FFLD+ G+
Sbjct: 601 FFLDNTGI 608
>SPBC14F5.06 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 593
Score = 874 bits (2257), Expect = 0.0
Identities = 435/604 (72%), Positives = 509/604 (84%), Gaps = 11/604 (1%)
Query: 1 MSSKNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGI 60
MS TRIAIVSEDKC+PKKCRQEC+RSCPVV+TGKLCIEV PT +IAFISE LCIGCGI
Sbjct: 1 MSESLTRIAIVSEDKCRPKKCRQECRRSCPVVRTGKLCIEVNPTDRIAFISETLCIGCGI 60
Query: 61 CVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
CVKKCPF AI IINLPTNL+S+VTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL
Sbjct: 61 CVKKCPFGAINIINLPTNLESEVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
Query: 121 KILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
KIL+GK KPNLGR+++PP+W E++KYFRGSELQN+FTK++ED+IKA+IKPQYVD+IPRAI
Sbjct: 121 KILSGKMKPNLGRYDNPPDWAEVVKYFRGSELQNFFTKVVEDNIKALIKPQYVDHIPRAI 180
Query: 181 KGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQEA 240
K + V L+K R + ++ + +D L+N+LNREV LSGGELQRFAI Q+A
Sbjct: 181 KTGDKTVSGLIKAR--ANNNNFEEVMDHTDLQNLLNREVGHLSGGELQRFAIAAVATQKA 238
Query: 241 DVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSV 300
DVYMFDEPSSYLD+KQRL A +IRSLL T YVI VEHDLSVLDYLSDFVC++YGVPS+
Sbjct: 239 DVYMFDEPSSYLDIKQRLKAGRVIRSLLATTNYVIVVEHDLSVLDYLSDFVCVLYGVPSM 298
Query: 301 YGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMKR 360
YGVVTLP SVREGINIFLDGHIP+ENLRFR+EAL FR+ADA DE+ AD + + YPD
Sbjct: 299 YGVVTLPYSVREGINIFLDGHIPTENLRFRSEALTFRLADASDEITADRTAEYNYPDHVI 358
Query: 361 TQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQK 420
QGDF LT+++G FSD++I+V++GENGTGKTT K +A L +SMKPQ
Sbjct: 359 EQGDFKLTIKSGGFSDAEIIVLLGENGTGKTTFCKWMA---------KNSDLKISMKPQT 409
Query: 421 IAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLS 480
IAPKF GTVR LF K+IRA FLN +FQ++V KPL ID+IIDQEV +LSGGELQRVAI L+
Sbjct: 410 IAPKFQGTVRMLFLKKIRAAFLNGKFQSEVCKPLSIDNIIDQEVLNLSGGELQRVAICLA 469
Query: 481 LGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVF 540
LGM AD+YLIDEPSAYLDSEQRII SKVIRRFI++++KTAFIVEHDFIMATYLAD+VI+F
Sbjct: 470 LGMPADVYLIDEPSAYLDSEQRIIASKVIRRFIVNSRKTAFIVEHDFIMATYLADRVILF 529
Query: 541 DGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGNYF 600
+G PS+ A P+SLLTG N FLKNL+VTFRRDP + RPRINK DSQMD+EQK++GNYF
Sbjct: 530 EGQPSRDARCNPPQSLLTGMNTFLKNLDVTFRRDPNTLRPRINKFDSQMDQEQKNAGNYF 589
Query: 601 FLDH 604
FL++
Sbjct: 590 FLEN 593
>Hs20532766 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 599
Score = 848 bits (2191), Expect = 0.0
Identities = 411/604 (68%), Positives = 500/604 (82%), Gaps = 7/604 (1%)
Query: 1 MSSKNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGI 60
M+ K TRIAIV+ DKCKPKKCRQECK+SCPVV+ GKLCIEV P SKIA+ISE LCIGCGI
Sbjct: 1 MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGI 60
Query: 61 CVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
C+KKCPF A+ I+NLP+NL+ + THRY AN+FKLHRLP PRPG+VLGLVGTNGIGKSTAL
Sbjct: 61 CIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTAL 120
Query: 121 KILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
KILAGKQKPNLG+++DPP+WQEI+ YFRGSELQNYFTK+LEDD+KAIIKPQYVD IP+A
Sbjct: 121 KILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAA 180
Query: 181 KGPVQKVGELLKLRLE-KSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQE 239
KG V G +L + E K++ + +D+ LK R V LSGGELQRFA + C+Q+
Sbjct: 181 KGTV---GSILDRKDETKTQAIVCQQLDLTHLKE---RNVEDLSGGELQRFACAVVCIQK 234
Query: 240 ADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPS 299
AD++MFDEPSSYLDVKQRL AA+ IRSL+NP Y+I VEHDLSVLDYLSDF+C +YGVPS
Sbjct: 235 ADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPS 294
Query: 300 VYGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMK 359
YGVVT+P SVREGINIFLDG++P+ENLRFR +L F++A+ +E E + YP MK
Sbjct: 295 AYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMK 354
Query: 360 RTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQ 419
+ G+F L + AGEF+DS+I+VM+GENGTGKTT I++LAG + D+G ++P LNVS KPQ
Sbjct: 355 KKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQ 414
Query: 420 KIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVL 479
KI+PK TG+VRQL ++IR + +PQF TDV+KPL+I++IIDQEVQ LSGGELQRVA+ L
Sbjct: 415 KISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALAL 474
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
LG AD+YLIDEPSAYLDSEQR++ ++V++RFILH KKTAF+VEHDFIMATYLAD+VIV
Sbjct: 475 CLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIV 534
Query: 540 FDGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGNY 599
FDG+PSK A +P++LL G NKFL L +TFRRDP ++RPRINKL+S D EQK SGNY
Sbjct: 535 FDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNY 594
Query: 600 FFLD 603
FFLD
Sbjct: 595 FFLD 598
>Hs4506559 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 599
Score = 834 bits (2154), Expect = 0.0
Identities = 406/604 (67%), Positives = 494/604 (81%), Gaps = 7/604 (1%)
Query: 1 MSSKNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGI 60
M+ K TRIAIV+ DKCKPKKCRQECK+SCPVV+ GKLCIEV P SKIA+ISE LCIGCGI
Sbjct: 1 MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGI 60
Query: 61 CVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
C+KKCPF A+ I+NLP+NL+ + THRY AN+FKLHRLP PRPG+VLGLVGTNGIGKS AL
Sbjct: 61 CIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSAAL 120
Query: 121 KILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
KILAGKQKPNLG+++DPP+WQEI+ YFRGSELQNYFTK+LEDD+KAIIKPQYV R
Sbjct: 121 KILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVARFLRLA 180
Query: 181 KGPVQKVGELLKLRLE-KSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQE 239
KG V G +L + E K++ + +D+ LK R V LSGGELQRFA + C+Q+
Sbjct: 181 KGTV---GSILDRKDETKTQAIVCQQLDLTHLKE---RNVEDLSGGELQRFACAVVCIQK 234
Query: 240 ADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPS 299
AD++MFDEPSSYLDVKQRL AA+ IRSL+NP Y+I VEHDLSVLDYLSDF+C +YGVPS
Sbjct: 235 ADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPS 294
Query: 300 VYGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMK 359
YGVVT+P SVREGINIFLDG++P+ENLRFR +L F++A+ +E E + YP MK
Sbjct: 295 AYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMK 354
Query: 360 RTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQ 419
+ G+F L + AGEF+DS+I+VM+GENGTGKTT I++LAG + D+G ++P LNVS KPQ
Sbjct: 355 KKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQ 414
Query: 420 KIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVL 479
KI+PK TG+VRQL ++IR + +PQF TDV+KPL+I++IIDQEVQ LSGGELQRV + L
Sbjct: 415 KISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVRLRL 474
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
LG AD+YLIDEPSAYLDSEQR++ ++V++RFILH KKTAF+VEHDFIMATYLAD+VIV
Sbjct: 475 CLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIV 534
Query: 540 FDGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGNY 599
FDG+PSK A +P++LL G NKFL L +TFRRDP ++RPRINKL+S D EQK SGNY
Sbjct: 535 FDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNY 594
Query: 600 FFLD 603
FFLD
Sbjct: 595 FFLD 598
>7295014 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 611
Score = 825 bits (2132), Expect = 0.0
Identities = 399/600 (66%), Positives = 493/600 (81%), Gaps = 5/600 (0%)
Query: 4 KNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGICVK 63
K TRIAIVS+DKCKPK+CRQECK++CPVV+ GKLCIEV PTSKIA +SE LCIGCGICVK
Sbjct: 12 KQTRIAIVSDDKCKPKRCRQECKKTCPVVRMGKLCIEVTPTSKIASLSEELCIGCGICVK 71
Query: 64 KCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKIL 123
KCPF+AI IINLP+NL+ THRYS NSFKLHRLP PRPG+VLGLVG NGIGKSTALKIL
Sbjct: 72 KCPFEAITIINLPSNLEKHTTHRYSKNSFKLHRLPIPRPGEVLGLVGQNGIGKSTALKIL 131
Query: 124 AGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGP 183
AGKQKPNLG++ +PP+W EI+ YFRGSELQNYFTK+LED++KA++KPQYVD IP+A++G
Sbjct: 132 AGKQKPNLGKYANPPDWTEILSYFRGSELQNYFTKILEDNLKALVKPQYVDQIPKAVRGA 191
Query: 184 VQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQEADVY 243
V G+LL + E+ + ++L L ++ +RE++ LSGGELQRFAI M C+Q AD++
Sbjct: 192 V---GDLLDKKDERELQT--KICEMLDLSHIRDREIAQLSGGELQRFAIAMVCIQNADIF 246
Query: 244 MFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSVYGV 303
MFDEPSSYLDVKQRLNAAL IRSLL+PT ++I VEHDLSVLDYLSDF+C +YGVP YGV
Sbjct: 247 MFDEPSSYLDVKQRLNAALTIRSLLHPTKFIIVVEHDLSVLDYLSDFICCLYGVPGCYGV 306
Query: 304 VTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMKRTQG 363
VT+P SVREGINIFLDG +P+EN+RFRTE+L F+++++ E E + YP M +T G
Sbjct: 307 VTMPFSVREGINIFLDGFVPTENMRFRTESLTFKVSESATEEEIKRMNHYVYPAMVKTLG 366
Query: 364 DFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAP 423
F LTVE G FSDS+ILV++GENGTGKTT I++LAG + D ++P LN+S KPQKI+P
Sbjct: 367 KFELTVEKGHFSDSEILVLLGENGTGKTTFIRMLAGNLQPDGEVELPMLNISYKPQKISP 426
Query: 424 KFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGM 483
KF VR L +IR +++PQF DV+KP+KI++I+DQEVQ+LSGGELQRVA+VL LG
Sbjct: 427 KFQNHVRHLLHDKIRDAYVHPQFIADVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 486
Query: 484 NADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDGI 543
AD+YLIDEPSAYLDSEQR++ +KVI+R+ILH KKT F+VEHDFIMATYLAD+VIV +G
Sbjct: 487 PADVYLIDEPSAYLDSEQRLVAAKVIKRYILHAKKTGFVVEHDFIMATYLADRVIVIEGQ 546
Query: 544 PSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGNYFFLD 603
PS + A +P+SLL G N+FL+ L +TFRRDP +FRPRINK +S D EQK SG +FFL+
Sbjct: 547 PSVKTTAFSPQSLLNGMNRFLELLGITFRRDPNNFRPRINKNNSVKDTEQKRSGQFFFLE 606
>At4g19210 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 600
Score = 819 bits (2115), Expect = 0.0
Identities = 409/605 (67%), Positives = 496/605 (81%), Gaps = 8/605 (1%)
Query: 1 MSSKNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGI 60
M+ + TRIAIVS D+CKPKKCRQECK+SCPVVKTGKLCIEV SK+AFISE LCIGCGI
Sbjct: 1 MADRLTRIAIVSSDRCKPKKCRQECKKSCPVVKTGKLCIEVTVGSKLAFISEELCIGCGI 60
Query: 61 CVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
CVKKCPF+AIQIINLP +L+ THRY AN+FKLHRLP PRPGQVLGLVGTNGIGKSTAL
Sbjct: 61 CVKKCPFEAIQIINLPRDLEKDTTHRYGANTFKLHRLPVPRPGQVLGLVGTNGIGKSTAL 120
Query: 121 KILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
KILAGK KPNLGRF PP+WQEI+ +FRGSELQNYFT++LED++KAIIKPQYVD+IPRA+
Sbjct: 121 KILAGKLKPNLGRFTSPPDWQEILTHFRGSELQNYFTRILEDNLKAIIKPQYVDHIPRAV 180
Query: 181 KGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQEA 240
KG VGE+L + E+ K A+ D L+L V++R+V LSGGELQRFAI + +Q A
Sbjct: 181 KG---NVGEVLDQKDERDK-KAELCAD-LELNQVIDRDVENLSGGELQRFAIAVVAIQNA 235
Query: 241 DVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSV 300
++YMFDEPSSYLDVKQRL AA ++RSLL P +YVI VEHDLSVLDYLSDF+C +YG P
Sbjct: 236 EIYMFDEPSSYLDVKQRLKAAQVVRSLLRPNSYVIVVEHDLSVLDYLSDFICCLYGKPGA 295
Query: 301 YGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDEL--EADASRAFTYPDM 358
YGVVTLP SVREGINIFL G +P+ENLRFR E+L F++A+ E E + + YP M
Sbjct: 296 YGVVTLPFSVREGINIFLAGFVPTENLRFRDESLTFKVAETPQESAEEIQSYARYKYPTM 355
Query: 359 KRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKP 418
+TQG+F L V GEF+DSQI+VM+GENGTGKTT I++L + + ++IP+ NVS KP
Sbjct: 356 TKTQGNFRLRVSEGEFTDSQIIVMLGENGTGKTTFIRMLVFS-SSMIYREIPEFNVSYKP 414
Query: 419 QKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIV 478
QKI+PKF +VR L ++IR +++PQF +DV+KPL+I+ ++DQEV +LSGGELQRVA+
Sbjct: 415 QKISPKFQNSVRHLLHQKIRDSYMHPQFMSDVMKPLQIEQLMDQEVVNLSGGELQRVALT 474
Query: 479 LSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVI 538
L LG ADIYLIDEPSAYLDSEQRI+ SKVI+RFILH KKTAF+VEHDFIMATYLAD+VI
Sbjct: 475 LCLGKPADIYLIDEPSAYLDSEQRIVASKVIKRFILHAKKTAFVVEHDFIMATYLADRVI 534
Query: 539 VFDGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGN 598
V++G PS A P+SLL+G N FL +LN+TFRRDPT+FRPRINKL+S D+EQKS+G+
Sbjct: 535 VYEGQPSIDCTANCPQSLLSGMNLFLSHLNITFRRDPTNFRPRINKLESTKDREQKSAGS 594
Query: 599 YFFLD 603
Y++LD
Sbjct: 595 YYYLD 599
>At3g13640 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 603
Score = 777 bits (2006), Expect = 0.0
Identities = 396/609 (65%), Positives = 478/609 (78%), Gaps = 13/609 (2%)
Query: 1 MSSKNTRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGI 60
MS + TRIAIVSED+CKPKKCRQECK+SCPVVKTGKLCIEV TSK AFISE LCIGCGI
Sbjct: 1 MSDRLTRIAIVSEDRCKPKKCRQECKKSCPVVKTGKLCIEVGSTSKSAFISEELCIGCGI 60
Query: 61 CVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTAL 120
CVKKCPF+AIQIINLP +L THRY AN FKLHRLP PRPGQVLGLVGTNGIGKSTAL
Sbjct: 61 CVKKCPFEAIQIINLPKDLAKDTTHRYGANGFKLHRLPIPRPGQVLGLVGTNGIGKSTAL 120
Query: 121 KILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAI 180
KILAGK KPNLGRF PP+W+EI+ +FRGSELQ+YF +++E+++K IKPQ+VD I +
Sbjct: 121 KILAGKLKPNLGRFNTPPDWEEILTHFRGSELQSYFIRVVEENLKTAIKPQHVDYIKEVV 180
Query: 181 KGPVQKVGELLKLR--LEKSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQ 238
+G + K+ E L R +E+ D ++L VL RE +SGGELQRFAI V+
Sbjct: 181 RGNLGKMLEKLDERGLMEEICAD-------MELNQVLEREARQVSGGELQRFAIAAVFVK 233
Query: 239 EADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVP 298
+AD+YMFDEPSSYLDV+QRL AA +IRSLL +YVI VEHDLSVLDYLSDFVC +YG P
Sbjct: 234 KADIYMFDEPSSYLDVRQRLKAAQVIRSLLRHDSYVIVVEHDLSVLDYLSDFVCCLYGKP 293
Query: 299 SVYGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADAS--RAFTYP 356
YGVVTLP SVREGIN+FL G IP+ENLRFR E+L FR+++ E + + + YP
Sbjct: 294 GAYGVVTLPFSVREGINVFLAGFIPTENLRFRDESLTFRVSETTQENDGEVKSYARYKYP 353
Query: 357 DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDG--QDIPKLNV 414
+M + GDF L V GEF+DSQI+VM+GENGTGKTT I++LAGA P ++G +IP+ NV
Sbjct: 354 NMTKQLGDFKLEVMEGEFTDSQIIVMLGENGTGKTTFIRMLAGAFPREEGVQSEIPEFNV 413
Query: 415 SMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQR 474
S KPQ K TVRQL +IR +PQF +DV++PL+I+ ++DQ V+ LSGGE QR
Sbjct: 414 SYKPQGNDSKRECTVRQLLHDKIRDACAHPQFMSDVIRPLQIEQLMDQVVKTLSGGEKQR 473
Query: 475 VAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLA 534
VAI L LG ADIYLIDEPSA+LDSEQRI SKVI+RFILH KKTAFIVEHDFIMATYLA
Sbjct: 474 VAITLCLGKPADIYLIDEPSAHLDSEQRITASKVIKRFILHAKKTAFIVEHDFIMATYLA 533
Query: 535 DKVIVFDGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQK 594
D+VIV++G P+ + A +P+SLL+G N FL +LN+TFRRDPT+FRPRINKL+S DKEQK
Sbjct: 534 DRVIVYEGQPAVKCIAHSPQSLLSGMNHFLSHLNITFRRDPTNFRPRINKLESIKDKEQK 593
Query: 595 SSGNYFFLD 603
++G+Y++LD
Sbjct: 594 TAGSYYYLD 602
>CE21713 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 610
Score = 764 bits (1973), Expect = 0.0
Identities = 377/600 (62%), Positives = 471/600 (77%), Gaps = 8/600 (1%)
Query: 7 RIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGICVKKCP 66
RIAIV +D+CKPK C CKR+CPV + GK CI V TS I+ ISE LCIGCGICVKKCP
Sbjct: 18 RIAIVEKDRCKPKNCGLACKRACPVNRQGKQCIVVEATSTISQISEILCIGCGICVKKCP 77
Query: 67 FDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGK 126
+DAI+IINLP NL ++ THRYS NSFKLHRLPTPR G+VLGLVGTNGIGKSTALKILAGK
Sbjct: 78 YDAIKIINLPANLANETTHRYSQNSFKLHRLPTPRCGEVLGLVGTNGIGKSTALKILAGK 137
Query: 127 QKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQK 186
QKPNLG F+ EW II +FRGSELQNYFT++LED +K +IKPQYVD IPRA KG V+K
Sbjct: 138 QKPNLGNFQKEQEWTTIINHFRGSELQNYFTRILEDTLKCVIKPQYVDQIPRAAKGTVEK 197
Query: 187 VGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQEADVYMFD 246
L + D+ ID ++L+ +L+RE+ LSGGELQRFAI M CVQ+ADVYMFD
Sbjct: 198 -----NLTRKHDNDNLNSVIDQMELRGLLDREIDQLSGGELQRFAIAMCCVQKADVYMFD 252
Query: 247 EPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTL 306
EPSSYLDVKQRL AA IIR ++ T YV+ VEHDL+VLDYLSDF+C +YGVP VYGVVTL
Sbjct: 253 EPSSYLDVKQRLKAAAIIRERVSDTNYVVVVEHDLAVLDYLSDFICCLYGVPGVYGVVTL 312
Query: 307 PSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMKRTQGDFS 366
PS VREGIN+FL+G I +EN+RFR L F+ ++ ++++ + YP M +T G+F
Sbjct: 313 PSGVREGINMFLEGFIRTENMRFRESKLSFKTSEQQEDIKRTGN--IKYPSMSKTLGNFH 370
Query: 367 LTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAI-PADDGQDIPKLNVSMKPQKIAPKF 425
L VEAG+FSDS+I+VM+GENGTGKTT+IK++AG++ P D+ ++P +++S KPQKI+PK
Sbjct: 371 LDVEAGDFSDSEIIVMLGENGTGKTTMIKMMAGSLKPEDENTELPHVSISYKPQKISPKS 430
Query: 426 TGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNA 485
TVR + +I+ + +PQF+TDV+ PL ++ ++D+ V+ LSGGELQRVA+ L LG A
Sbjct: 431 ETTVRFMLHDKIQNMYEHPQFKTDVMNPLMMEQLLDRNVKELSGGELQRVALALCLGKTA 490
Query: 486 DIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDGIPS 545
+YLIDEPSAYLDSEQR+ +KVI+RFI+H KKTAF+VEHDFIMATYLAD+V+VF+G PS
Sbjct: 491 SLYLIDEPSAYLDSEQRLHAAKVIKRFIMHAKKTAFVVEHDFIMATYLADRVVVFEGQPS 550
Query: 546 KQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINKLDSQMDKEQKSSGNYFFLDHN 605
+ A P+SLL G N+FLK L++TFRRD ++RPRINKLDS D +QK SG +FFLD N
Sbjct: 551 VKCTACKPQSLLEGMNRFLKMLDITFRRDQETYRPRINKLDSVKDVDQKKSGQFFFLDDN 610
>ECU11g1580 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 624
Score = 659 bits (1700), Expect = 0.0
Identities = 331/617 (53%), Positives = 436/617 (70%), Gaps = 25/617 (4%)
Query: 6 TRIAIVSEDKCKPKKCRQECKRSCPVVKTGKLCIEVMPTSKIAFISENLCIGCGICVKKC 65
TR+AIV+ + CKP +C EC+++CPV KTGK CI + K ISE LCIGC C KKC
Sbjct: 11 TRLAIVNFELCKPSQCASECRKACPVNKTGKECIRI---EKKCMISEVLCIGCSACQKKC 67
Query: 66 PFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAG 125
PF AI IINLPTNL ++THRY N FKLHRLP PRPG+VLGLVGTNGIGKSTALKIL+G
Sbjct: 68 PFKAISIINLPTNLTKEITHRYGTNGFKLHRLPIPRPGKVLGLVGTNGIGKSTALKILSG 127
Query: 126 KQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQ 185
+ KPNLG+++ PP W+ I+ YFRGSELQ YFTK+LE ++ K QY+D +P+ +K
Sbjct: 128 EIKPNLGKYDSPPGWETILGYFRGSELQGYFTKVLEGQLRITSKIQYIDRLPKLLKKRFS 187
Query: 186 -KVGELLK-LRLEKSKDDAKR-------------------YIDILQLKNVLNREVSALSG 224
+V ++K L L+ ++ D YI+ + L N+L+R+V LSG
Sbjct: 188 PEVKSMVKSLSLDGTETDTDNRLLVRSVLEEMDQRQRKDYYIEKMCLGNILDRDVEELSG 247
Query: 225 GELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVL 284
GELQR ++ ++C+Q++DVY+FDEPSSYLDVKQRL+AA IR L +YVI VEHDL++L
Sbjct: 248 GELQRLSLALACMQQSDVYIFDEPSSYLDVKQRLSAAKEIRELCEDNSYVIVVEHDLAIL 307
Query: 285 DYLSDFVCIIYGVPSVYGVVTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDE 344
D +SDF C++YG YGV+T P +++ INIFLDG+IP+EN+RFR L+F +++
Sbjct: 308 DLMSDFGCVLYGQSGAYGVITAPYAIKSAINIFLDGYIPTENMRFRPSELKFDISERPTR 367
Query: 345 LEADASRAFTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD 404
+A+ + Y M +T F L V+ G FSDS+I+V +GENG GKTTL+ L+AG I D
Sbjct: 368 -DAEKRAQYWYGGMTKTYESFRLEVKEGSFSDSEIIVFLGENGMGKTTLVGLIAGLIKPD 426
Query: 405 DGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEV 464
G + KL+ S+KPQKI PK+ GTVR+LF +IR+ F++ F DV+KPL I+ +Q+V
Sbjct: 427 RGDEFTKLSYSLKPQKILPKYKGTVRELFMSKIRSSFMDQSFVNDVIKPLSIEYTYEQQV 486
Query: 465 QHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVE 524
Q+LSGGELQR+AI + LG +A++YLIDEPSA+LDS+QRI SK+I+RFI N K AFIVE
Sbjct: 487 QNLSGGELQRIAIAMCLGKDANVYLIDEPSAFLDSDQRIAISKIIKRFIYSNGKIAFIVE 546
Query: 525 HDFIMATYLADKVIVFDGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPTSFRPRINK 584
HD I+ TYLADKV+VF G P + A P LL G N FLK+L+VTFRRD ++ RPR+NK
Sbjct: 547 HDLIVGTYLADKVVVFQGEPGVSSVASPPMGLLDGMNIFLKSLDVTFRRDSSNLRPRVNK 606
Query: 585 LDSQMDKEQKSSGNYFF 601
S D+ QK + YFF
Sbjct: 607 PGSAKDRIQKENNQYFF 623
>Hs17452992 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 288
Score = 353 bits (907), Expect = 3e-97
Identities = 182/321 (56%), Positives = 232/321 (71%), Gaps = 34/321 (10%)
Query: 244 MFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSVYGV 303
MF E S YLDVKQ L A+ I+SL+NP Y++ VE+DL VLDYLSDF+C +YGVPS YGV
Sbjct: 1 MFGETSRYLDVKQHLKPAITIQSLINPDRYIVVVEYDLGVLDYLSDFICCLYGVPSTYGV 60
Query: 304 VTLPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMKRTQG 363
VT+P SVR+GINIFLDG++P+ENLRF+ +L F++A+ +E E
Sbjct: 61 VTVPFSVRKGINIFLDGYVPTENLRFQDASLVFKVAETANEEEVK--------------- 105
Query: 364 DFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAP 423
MM ENG GKTT I++LAG + D+ ++P LNVS K QKI+P
Sbjct: 106 ------------------MMWENGMGKTTFIRMLAGRLEPDEEGEVPVLNVSYKLQKISP 147
Query: 424 KFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGM 483
K TG+VRQL ++IR + +PQF T+V+KPL+I++IIDQEVQ LSGGELQRVA+ L LG
Sbjct: 148 KSTGSVRQLLREKIRDAYTHPQFVTNVMKPLQIENIIDQEVQTLSGGELQRVALALCLGK 207
Query: 484 NADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDGI 543
AD+YLIDEPSAYLDSEQR++ ++V++RFILH KKTAF+VEHDFIMATYLAD VI+FDG+
Sbjct: 208 PADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADHVIIFDGV 267
Query: 544 PS-KQAFARAPESLLTGCNKF 563
PS K A +P++LL G N F
Sbjct: 268 PSTKNTVANSPQTLLAGMNTF 288
Score = 97.4 bits (241), Expect = 5e-20
Identities = 73/214 (34%), Positives = 110/214 (51%), Gaps = 43/214 (20%)
Query: 112 NGIGKSTALKILAGKQKPNLGRFEDPP-----EWQEIIKYFRGSELQNYFTKMLEDDIK- 165
NG+GK+T +++LAG+ +P+ E P + Q+I GS Q +L + I+
Sbjct: 110 NGMGKTTFIRMLAGRLEPD-EEGEVPVLNVSYKLQKISPKSTGSVRQ-----LLREKIRD 163
Query: 166 AIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALSGG 225
A PQ+V N+ + LQ++N++++EV LSGG
Sbjct: 164 AYTHPQFVTNVMKP-----------------------------LQIENIIDQEVQTLSGG 194
Query: 226 ELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALII-RSLLNPTTYVICVEHDLSVL 284
ELQR A+ + + ADVY+ DEPS+YLD +QRL AA ++ R +L+ VEHD +
Sbjct: 195 ELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMA 254
Query: 285 DYLSDFVCIIYGVPSVYG-VVTLPSSVREGINIF 317
YL+D V I GVPS V P ++ G+N F
Sbjct: 255 TYLADHVIIFDGVPSTKNTVANSPQTLLAGMNTF 288
>At4g30300 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 181
Score = 175 bits (444), Expect = 2e-43
Identities = 98/175 (56%), Positives = 126/175 (72%), Gaps = 6/175 (3%)
Query: 358 MKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGA---IPADDGQ--DIPKL 412
M T+GDF L + GEF+DSQI+VM+GENGTGKTT IK+LAG+ I + Q +IP+
Sbjct: 1 MTITRGDFKLRLNQGEFTDSQIIVMLGENGTGKTTFIKMLAGSKLDIDEEGSQVHEIPQF 60
Query: 413 NVSMKPQKIAP-KFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGE 471
+VS K Q ++ KF TVR L ++I + QF +DV+KPLKI++++D+ LSGGE
Sbjct: 61 SVSYKNQHMSNRKFEITVRDLIHRKIPNAYAEHQFVSDVMKPLKIEELMDKSFNKLSGGE 120
Query: 472 LQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHD 526
QRVA+ L LG +ADIYLIDEPSA+LDSEQRII SKVI+RFIL KK AF H+
Sbjct: 121 KQRVALALCLGKSADIYLIDEPSAFLDSEQRIIASKVIKRFILQMKKAAFARFHN 175
Score = 66.6 bits (161), Expect = 1e-10
Identities = 46/165 (27%), Positives = 89/165 (53%), Gaps = 23/165 (13%)
Query: 104 QVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDD 163
Q++ ++G NG GK+T +K+LAG + L E+ + EI ++ + Q+ + E
Sbjct: 21 QIIVMLGENGTGKTTFIKMLAGSK---LDIDEEGSQVHEIPQFSVSYKNQHMSNRKFEIT 77
Query: 164 IKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALS 223
++ +I + IP A Q V +++K L+++ ++++ + LS
Sbjct: 78 VRDLIHRK----IPNAY-AEHQFVSDVMKP---------------LKIEELMDKSFNKLS 117
Query: 224 GGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL 268
GGE QR A+ + + AD+Y+ DEPS++LD +QR+ A+ +I+ +
Sbjct: 118 GGEKQRVALALCLGKSADIYLIDEPSAFLDSEQRIIASKVIKRFI 162
>Hs16166977 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 124
Score = 150 bits (378), Expect = 7e-36
Identities = 71/121 (58%), Positives = 96/121 (78%)
Query: 353 FTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKL 412
+ YP MK+ G+F L + A EF+DS+I+VM+GENGTGKTT I++LAG + ++G ++P L
Sbjct: 4 YKYPGMKKKMGEFELAIVAREFTDSEIMVMLGENGTGKTTFIRMLAGRLKPEEGGEVPVL 63
Query: 413 NVSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGEL 472
NVS KPQKI+ K TG+VRQL ++IR + +PQF TDV+KPL+I++I DQEVQ LSGGEL
Sbjct: 64 NVSYKPQKISRKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENITDQEVQTLSGGEL 123
Query: 473 Q 473
Q
Sbjct: 124 Q 124
>Hs18600950_1 [A] KOG0063 RNAse L inhibitor ABC superfamily
Length = 240
Score = 105 bits (262), Expect = 2e-22
Identities = 49/66 (74%), Positives = 55/66 (83%)
Query: 244 MFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSVYGV 303
MFDE S YLDVKQRL A+ IRSL+NP Y+I VEHDLSVLDYLSDF+C +YGVPS YGV
Sbjct: 1 MFDEASGYLDVKQRLKPAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGV 60
Query: 304 VTLPSS 309
VT+P S
Sbjct: 61 VTMPFS 66
Score = 50.1 bits (118), Expect = 1e-05
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 489 LIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDGIPSKQA 548
+ DE S YLD +QR+ + IR I + + +VEHD + YL+D + G+PS
Sbjct: 1 MFDEASGYLDVKQRLKPAITIRSLI-NPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYG 59
Query: 549 FARAPESLLTGCNKFLKNLNVTFR 572
P S C KF LN FR
Sbjct: 60 VVTMPFSNSKICQKFYAELNSLFR 83
>ECU05g1190 [EJ] KOG0062 ATPase component of ABC transporters with duplicated
ATPase domains/Translation elongation factor EF-3b
Length = 554
Score = 68.9 bits (167), Expect = 2e-11
Identities = 113/453 (24%), Positives = 185/453 (39%), Gaps = 101/453 (22%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G+ GLVG NGIGK+T LK + + RF P RG + M++
Sbjct: 115 GRKYGLVGRNGIGKTTLLKAIRKR------RFGIP----------RGMRIY-----MIKQ 153
Query: 163 DIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSAL 222
D+ I + V++ A + G +L L +KD A +KN+ + L
Sbjct: 154 DL---IVDETVEDFAGA------EAGRILN-GLGFTKDMA--------VKNMRD-----L 190
Query: 223 SGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK---------QRLNAALII---RSLLNP 270
SGG R + + + D+ + DEP++YLD+ + L +I+ R+ LN
Sbjct: 191 SGGWRMRAHLAKAINADPDLLLLDEPTNYLDINALSWLEGKIKELKTVIIVSHDRNFLNN 250
Query: 271 TTYVICVEHDLSVLDYLSDFVCIIYG----VPSVYGVVTLPSSVREGINIFLDGHIPSEN 326
TT +I +DL + Y ++ + S VRE + F+D
Sbjct: 251 TTEMILHLNDLKIDVYRGNYESFVKQRKEKTASARREYESQLLVREHMQSFID------- 303
Query: 327 LRFRTEALQFRMADAGDELEADASRAFTYPDMKRTQGDFSLTVEAG---EF--------- 374
RFR A + + + ++ A + FS T G EF
Sbjct: 304 -RFRYNAKRASLVQSKIKMLAKMPTLVAPKQDPVIKFTFSSTPAQGALIEFVNVVFSYGC 362
Query: 375 ------------SDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDI--PKLNVSMKPQK 420
SDS+I+V+ G NG GK+T +KLLAG + A +G I P L V Q
Sbjct: 363 GKVLGGLSMKINSDSRIVVV-GANGQGKSTFLKLLAGKLEATEGSIIRAPSLRVGYFAQH 421
Query: 421 IAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVK-PLKIDDIIDQEVQHLSGGELQRVAIVL 479
L F + + + + + L +D +Q + LSGG+ R+ +
Sbjct: 422 HIDHLRVNENVLDF--MMKSYTQEEARRALASFGLSVD---NQCIGTLSGGQKSRLGFAI 476
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRF 512
G++ ++ ++DEP+ +LD E ++ + RF
Sbjct: 477 INGLSPNLLVLDEPTNHLDMESIDALAEALGRF 509
>ECU03g0390 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 590
Score = 66.6 bits (161), Expect = 1e-10
Identities = 53/210 (25%), Positives = 89/210 (42%), Gaps = 37/210 (17%)
Query: 102 PGQVLGLVGTNGIGKSTALKILAGKQKPNL---------GRFEDPPEWQEIIKY----FR 148
P + L+GT+G GK+T + LAG+ PN+ W EI+ Y F
Sbjct: 39 PSTMTALMGTSGAGKTTLMNALAGRISPNMHLKGEILLNSHPRSKDTWPEIVGYVEQEFH 98
Query: 149 GSELQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDI 208
E Q F + + ++ GE ++ +K + + + +
Sbjct: 99 AYEYQTVFETL-------------------SFASKIKMRGEEME---QKVVNRIEEIVSL 136
Query: 209 LQLKNVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL 268
L LKN N ++ LSGGE +R +IG+ + + DEP+S LD LN ++R L
Sbjct: 137 LGLKNAKNTYIANLSGGERKRVSIGVELLGNPSILFCDEPTSGLDSFNALNILSLLRDLS 196
Query: 269 NPTTYVICVEHDLS--VLDYLSDFVCIIYG 296
N V+ H S ++++ F+ + G
Sbjct: 197 NMGKTVLVTIHQPSYEMINFFDKFILMSMG 226
>SPBC2G5.09c [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1035
Score = 64.3 bits (155), Expect = 5e-10
Identities = 56/211 (26%), Positives = 107/211 (50%), Gaps = 31/211 (14%)
Query: 352 AFTYPDMKRTQ---GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADD--- 405
+F YPD +R + SL++EA E + ++G +G+GK+TL++LL P++D
Sbjct: 804 SFAYPDSERNHLALNNVSLSIEAREK-----VAIVGISGSGKSTLVELLRKTYPSEDIYI 858
Query: 406 -GQDIPKLNVSMKPQKIA-----PKFTGT--VRQLFFKRIR-----AQFLNPQFQTDVVK 452
G + ++ + +K+A P G+ + L + R L+ + T+V++
Sbjct: 859 DGYPLTNIDTNWLLKKVAIVDQKPHLLGSTILESLLYGVDRDINSVMDALDKTYMTEVIQ 918
Query: 453 --PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIR 510
P +D + + ++ SGG++QR+A +L N + ++DE ++ LDS+ ++ K I+
Sbjct: 919 NLPNGLDTPLLEFSKNFSGGQIQRLAFARALLRNPRLLILDECTSALDSKSSLLLEKTIQ 978
Query: 511 RFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
T I+ H + LAD++IV D
Sbjct: 979 NL----SCTVLIITHQPSLMK-LADRIIVMD 1004
>CE03260 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1318
Score = 61.2 bits (147), Expect = 4e-09
Identities = 70/287 (24%), Positives = 123/287 (42%), Gaps = 52/287 (18%)
Query: 272 TYVICVEHDLS-VLDYLSDFVCIIYGVPSVYGVVTLPSSVREGINIFLDGHIP------- 323
+Y+ V + +S Y + FVC G P +Y + IN + G +
Sbjct: 979 SYIQSVNNAISQTFMYFAMFVCYGVGTPLMYHGIVEAEPTFRAINCMMMGSVAVMHSSHN 1038
Query: 324 -SENLRFRTEA-----LQFRMADAGDELEAD----------ASRAFTYPD--MKRTQGDF 365
E ++ +T A L +R + GD +E + S F+YP M+ D
Sbjct: 1039 FPEFVKAKTAAGMLFKLIYRKSKTGDVMEGNNTEIRGNVLFESVKFSYPQRPMQPVMTDL 1098
Query: 366 SLTVEAGEFSDSQILVMMGENGTGKTTLIKLL------AGAIPADDGQDIPKLNVSMKPQ 419
+ +G Q + ++G +GTGK+T I +L +G DGQ+I L++
Sbjct: 1099 HFSAHSG-----QTVALVGPSGTGKSTCIAMLERFYDVSGGALRIDGQNIKSLSLHHLRT 1153
Query: 420 KIA-----PK-FTGTVRQ---LFFKRIRAQFLNPQFQTDVVK------PLKIDDIIDQEV 464
++A P+ F GT+++ K + + ++ + P ID + ++
Sbjct: 1154 QMALVGQEPRLFAGTIKENVCFGLKDVSVEKVHQALELANASRFLANLPAGIDTEVGEKG 1213
Query: 465 QHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRR 511
LSGG+ QR+AI +L + I L+DE ++ LDSE + + R
Sbjct: 1214 GQLSGGQKQRIAIARALVRDPKILLLDEATSALDSESERAVQEALDR 1260
Score = 50.8 bits (120), Expect = 6e-06
Identities = 59/218 (27%), Positives = 96/218 (43%), Gaps = 43/218 (19%)
Query: 353 FTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLA------GAIPAD 404
F YP K+ + +LTV+ G + ++G +G GK+T + LL G
Sbjct: 424 FRYPTRKKVKVLNGLNLTVKPGTS-----VALVGHSGCGKSTSVGLLTRLYEPEGGKVMI 478
Query: 405 DGQDIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRAQFL--NPQF-QTDVVKPLKIDD 458
DGQD+ LN+ K G V+Q LF I L NP + D+++ K+ +
Sbjct: 479 DGQDVRSLNIDW-----LRKTVGIVQQEPILFNDTIHNNLLIGNPSATREDMIRVCKMAN 533
Query: 459 ---------------IIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRI 503
I D VQ LSGG+ QRVAI +L + + L+DE ++ LD++
Sbjct: 534 AHDFIQKMPNGYETMIGDGSVQ-LSGGQKQRVAIARTLIRDPKVLLLDEATSALDAQSES 592
Query: 504 ICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
+ + +T ++ H + ADK++ F+
Sbjct: 593 VVQSALNN--AAKGRTTIMIAHR-LSTIREADKIVFFE 627
>7295535 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1500
Score = 61.2 bits (147), Expect = 4e-09
Identities = 44/166 (26%), Positives = 81/166 (48%), Gaps = 14/166 (8%)
Query: 382 MMGENGTGKTTLIKLLAGAIPADDGQ---DIPKLNVSMKPQKIAPKFTGTVRQLFFKRIR 438
++G+NG GK+T+ KLL G + D GQ + P ++ + + P T T F+ R+R
Sbjct: 1184 LLGKNGAGKSTIFKLLTGQLQPDVGQIYFEQPGISYCPQSNPLDPLLTTTECIRFYGRLR 1243
Query: 439 A-----QFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEP 493
QFL+ T ++P K D +V++LSGG +++ + ++ L+DEP
Sbjct: 1244 GIRDLDQFLDRVLDTYELRPYK-----DVQVRNLSGGNRRKLTVAVTCCGCTPTVLMDEP 1298
Query: 494 SAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
++ +D R + I + +L ++ + H +L +V V
Sbjct: 1299 TSDMDPVTRDMVYATIEQLLL-ARRAVVLTSHSVSEIEHLCQRVAV 1343
Score = 52.8 bits (125), Expect = 2e-06
Identities = 42/181 (23%), Positives = 85/181 (46%), Gaps = 19/181 (10%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDI----PKLNVSMKPQKIAPKFTGT 428
+F+ +Q+ ++G NG GK+TLIKLL G I G+ + ++ V + + P T
Sbjct: 381 DFARNQVSCLLGRNGAGKSTLIKLLTGQIRQSSGKVLLAGEHQVGVCWQDNILIPTLTAR 440
Query: 429 VRQLFFKRIRAQFLNP-------QFQTDVVKPLKIDDIIDQEVQ---HLSGGELQRVAIV 478
+ +I+ + P + +++V + L+ + E LSGG +R+ +
Sbjct: 441 EHLQLYAQIK---IPPGGSGGVEEIRSEVAQTLQSLNFGKHESYPSWQLSGGYRRRLCVA 497
Query: 479 LSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVI 538
++ + + ++DEP +D++ R ++I R L + H A YL+D ++
Sbjct: 498 IAFIASPSVVILDEPCNGVDAKARKDIWQLIER--LRQGRAVIFATHFMDEAKYLSDSLV 555
Query: 539 V 539
+
Sbjct: 556 I 556
>At5g64840 [R] KOG0927 Predicted transporter (ABC superfamily)
Length = 692
Score = 60.8 bits (146), Expect = 6e-09
Identities = 50/207 (24%), Positives = 94/207 (45%), Gaps = 29/207 (14%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G+ +GLVG NG GK+T L+I+ G+++P+ G ++ F E + +K + +
Sbjct: 123 GEKVGLVGVNGAGKTTQLRIITGQEEPDSGNVIKAKPNMKVA--FLSQEFEVSMSKTVRE 180
Query: 163 DIKAIIKPQY-----VDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNV--- 214
+ K + ++ + +AI+G V + L RL D +R + L +V
Sbjct: 181 EFMTAFKEEMEITEKLEKVQKAIEGSVDDLD--LMGRLLDEFDLLQRRAQAVNLDSVDAK 238
Query: 215 --------------LNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNA 260
+R V++ SGG R ++G +Q+ D+ + DEP+++LD+
Sbjct: 239 ISKLMPELGFAPEDADRLVASFSGGWQMRMSLGKILLQDPDLLLLDEPTNHLDLD---TI 295
Query: 261 ALIIRSLLNPTTYVICVEHDLSVLDYL 287
+ L ++ + HD + LD L
Sbjct: 296 EWLEGYLQKQDVPMVIISHDRAFLDQL 322
Score = 54.3 bits (129), Expect = 5e-07
Identities = 53/190 (27%), Positives = 87/190 (44%), Gaps = 31/190 (16%)
Query: 92 FKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSE 151
FK L R G+ + ++G NG GKST LK++ G +KP G E+I +
Sbjct: 440 FKKANLSIER-GEKIAILGPNGCGKSTLLKLIMGLEKPVKG---------EVI-LGEHNV 488
Query: 152 LQNYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQL 211
L NYF + + V ++ + + V + E + DD K +
Sbjct: 489 LPNYFEQNQAE----------VLDLDKTVLETVCEAAE------DWRSDDIKGLLGRCNF 532
Query: 212 K-NVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNP 270
K ++L+R+VS LSGGE R A V + + + DEP+++LD+ + ++ ++
Sbjct: 533 KADMLDRKVSLLSGGEKARLAFCKFMVTPSTLLVLDEPTNHLDIPSK---EMLEEAINEY 589
Query: 271 TTYVICVEHD 280
VI V HD
Sbjct: 590 QGTVIAVSHD 599
>7297388 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1327
Score = 60.8 bits (146), Expect = 6e-09
Identities = 50/196 (25%), Positives = 92/196 (46%), Gaps = 31/196 (15%)
Query: 364 DFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAP 423
D+SL +L ++G G+GK++LI+ + G +PA+ G+ K+N SM P
Sbjct: 432 DYSLNGVNLRVQPGTMLGIVGRTGSGKSSLIQAILGELPAESGEI--KVNGSMSYASQEP 489
Query: 424 -KFTGTVRQ-----------LFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGE 471
F+GTVRQ + K ++ L F+ + P K I+ + LSGG+
Sbjct: 490 WLFSGTVRQNILFGQPMDRRRYAKVVKKCALERDFE---LLPFKDKTIVGERGASLSGGQ 546
Query: 472 LQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMAT 531
R+++ ++ IYL+D+P + +D+ + R + ++ E I+AT
Sbjct: 547 KARISLARAVYRETSIYLLDDPLSAVDTH--------VARHLFEQCMRGYLRERIVILAT 598
Query: 532 YL------ADKVIVFD 541
+ AD++++ D
Sbjct: 599 HQLQFLQHADQIVIMD 614
>CE16149 [U] KOG0058 Peptide exporter ABC superfamily
Length = 733
Score = 59.7 bits (143), Expect = 1e-08
Identities = 60/220 (27%), Positives = 100/220 (45%), Gaps = 42/220 (19%)
Query: 352 AFTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL-------AGAIPAD 404
AF Y D + S V AG+ I ++G +G+GK+T+ LL +G I D
Sbjct: 488 AFGYADRDPLFHNISFDVPAGK-----ITAVVGSSGSGKSTIASLLLRLYDPTSGRILVD 542
Query: 405 DGQDIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRAQF----LNPQFQTD--VVK--- 452
G D+ ++ S + I GTV Q LF I+ L P+ TD +V
Sbjct: 543 -GTDLKDIDPSYWRRHI-----GTVGQEPVLFSTTIKENIIYGSLEPENVTDAEIVSAAD 596
Query: 453 -----------PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQ 501
P+K D + + LSGG+ QR+AI +L +I ++DE ++ LD+
Sbjct: 597 QSNADEFISRFPIKYDTKVGEHGSTLSGGQKQRIAIARALVNKPNILIMDEATSALDASS 656
Query: 502 RIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
+ + + + ++K+T I+ H + AD+++V D
Sbjct: 657 EYLVRIALNKLLANSKQTVMIIAHRLSTIKH-ADQIVVVD 695
Score = 55.1 bits (131), Expect = 3e-07
Identities = 54/224 (24%), Positives = 94/224 (41%), Gaps = 28/224 (12%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFE---------DPPEWQEIIKYFRGSELQ 153
G++ +VG++G GKST +L P GR DP W+ I G E
Sbjct: 508 GKITAVVGSSGSGKSTIASLLLRLYDPTSGRILVDGTDLKDIDPSYWRRHIGTV-GQEPV 566
Query: 154 NYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLK- 212
+ T + E+ I ++P+ V + E++ + + D+ +I +K
Sbjct: 567 LFSTTIKENIIYGSLEPENVTD------------AEIVSAADQSNADE---FISRFPIKY 611
Query: 213 -NVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL-NP 270
+ S LSGG+ QR AI + V + ++ + DE +S LD + + LL N
Sbjct: 612 DTKVGEHGSTLSGGQKQRIAIARALVNKPNILIMDEATSALDASSEYLVRIALNKLLANS 671
Query: 271 TTYVICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPSSVREGI 314
V+ + H LS + + V + G + G ++ +GI
Sbjct: 672 KQTVMIIAHRLSTIKHADQIVVVDRGSVAESGSYDELIAIPDGI 715
>Hs20143975 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 646
Score = 59.3 bits (142), Expect = 2e-08
Identities = 58/208 (27%), Positives = 89/208 (41%), Gaps = 33/208 (15%)
Query: 104 QVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKM---- 159
+++G++G +G GKST + ILAG ++ + +I+ R EL+ F KM
Sbjct: 96 ELIGIMGPSGAGKSTFMNILAGYRESGMKG--------QILVNGRPRELRT-FRKMSCYI 146
Query: 160 LEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKL--RLEKSKDDAKRYIDILQLKNVLNR 217
++DD+ +P V LKL + E K+ + L L + +
Sbjct: 147 MQDDML----------LPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHT 196
Query: 218 EVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICV 277
+ LSGG+ +R AI + V V FDEP+S LD +++SL +IC
Sbjct: 197 RTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICT 256
Query: 278 EHDLSV--------LDYLSDFVCIIYGV 297
H S L LS CI GV
Sbjct: 257 IHQPSAKLFEMFDKLYILSQGQCIFKGV 284
>At3g62150 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1292
Score = 58.9 bits (141), Expect = 2e-08
Identities = 52/198 (26%), Positives = 92/198 (46%), Gaps = 31/198 (15%)
Query: 352 AFTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ-D 408
+F YP Q D L++ AG+ + ++GE+G+GK+T+I LL D GQ
Sbjct: 1054 SFKYPSRPDVQIFQDLCLSIRAGK-----TIALVGESGSGKSTVIALLQRFYDPDSGQIT 1108
Query: 409 IPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRAQFL----NPQFQTDVVKPLKI----- 456
+ + + K + TG V Q LF + IRA +T++V ++
Sbjct: 1109 LDGVEIKTLQLKWLRQQTGLVSQEPVLFNETIRANIAYGKGGDATETEIVSAAELSNAHG 1168
Query: 457 ---------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSK 507
D ++ + LSGG+ QRVAI ++ + + L+DE ++ LD+E +
Sbjct: 1169 FISGLQQGYDTMVGERGVQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQD 1228
Query: 508 VIRRFILHNKKTAFIVEH 525
+ R +++ +T +V H
Sbjct: 1229 ALDRVMVN--RTTVVVAH 1244
Score = 52.0 bits (123), Expect = 3e-06
Identities = 56/219 (25%), Positives = 95/219 (42%), Gaps = 18/219 (8%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
R G+ + LVG +G GKST + +L RF DP Q + G E++ K L
Sbjct: 1074 RAGKTIALVGESGSGKSTVIALLQ--------RFYDPDSGQITLD---GVEIKTLQLKWL 1122
Query: 161 EDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKD--DAKRYIDILQ--LKNVLN 216
+ + + N K G+ + + + + +A +I LQ ++
Sbjct: 1123 RQQTGLVSQEPVLFNETIRANIAYGKGGDATETEIVSAAELSNAHGFISGLQQGYDTMVG 1182
Query: 217 REVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTTYVI 275
LSGG+ QR AI + V++ V + DE +S LD + +R+ + R ++N TT V
Sbjct: 1183 ERGVQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRVMVNRTTVV- 1241
Query: 276 CVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPSSVREGI 314
V H LS + + GV G ++++G+
Sbjct: 1242 -VAHRLSTIKNADVIAVVKNGVIVEKGKHETLINIKDGV 1279
Score = 50.8 bits (120), Expect = 6e-06
Identities = 50/199 (25%), Positives = 95/199 (47%), Gaps = 22/199 (11%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G + LVG +G GKST + ++ RF DP + I G L+ + K +
Sbjct: 431 GSTVALVGQSGSGKSTVVSLIE--------RFYDPQSGEVRID---GINLKEFQLKWIRS 479
Query: 163 DIKAIIKPQYVDNIPRAIKGPV---QKVGELLKLRLEKSKDDAKRYIDILQ--LKNVLNR 217
I + + + +IK + ++ + ++R +A ++ID L L ++
Sbjct: 480 KIGLVSQEPVL--FTSSIKENIAYGKENATVEEIRKATELANASKFIDKLPQGLDTMVGE 537
Query: 218 EVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTTYVIC 276
+ LSGG+ QR A+ + +++ + + DE +S LD + +R+ + R ++N TT V
Sbjct: 538 HGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERIVQEALDRIMVNRTTVV-- 595
Query: 277 VEHDLSVLDYLSDFVCIIY 295
V H LS + +D + +I+
Sbjct: 596 VAHRLSTVRN-ADMIAVIH 613
>At1g02530 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1273
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/202 (26%), Positives = 89/202 (43%), Gaps = 37/202 (18%)
Query: 352 AFTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ-- 407
+FTYP Q D LT+ AG+ + ++GE+G+GK+T+I LL D GQ
Sbjct: 1033 SFTYPARPGIQIFRDLCLTIRAGK-----TVALVGESGSGKSTVISLLQRFYDPDSGQIT 1087
Query: 408 ----DIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKI------- 456
++ KL + Q++ G LF IRA + + +I
Sbjct: 1088 LDGVELKKLQLKWLRQQMG--LVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELA 1145
Query: 457 -------------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRI 503
D ++ ++ LSGG+ QRVAI ++ I L+DE ++ LD+E
Sbjct: 1146 NAHKFISSIQQGYDTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESER 1205
Query: 504 ICSKVIRRFILHNKKTAFIVEH 525
+ + R I++ +T +V H
Sbjct: 1206 LVQDALDRVIVN--RTTVVVAH 1225
Score = 54.7 bits (130), Expect = 4e-07
Identities = 60/204 (29%), Positives = 96/204 (46%), Gaps = 23/204 (11%)
Query: 99 TPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTK 158
T R G+ + LVG +G GKST + +L RF DP Q + G EL+ K
Sbjct: 1051 TIRAGKTVALVGESGSGKSTVISLLQ--------RFYDPDSGQITLD---GVELKKLQLK 1099
Query: 159 MLEDDIKAI-IKPQYVDNIPRAI----KGPVQKVGELLKLRLEKSKDDAKRYIDILQ--L 211
L + + +P ++ RA KG + E ++ +A ++I +Q
Sbjct: 1100 WLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATES-EIIAAAELANAHKFISSIQQGY 1158
Query: 212 KNVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNP 270
V+ + LSGG+ QR AI + V+E + + DE +S LD + +RL + R ++N
Sbjct: 1159 DTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRVIVNR 1218
Query: 271 TTYVICVEHDLSVLDYLSDFVCII 294
TT V V H LS + +D + I+
Sbjct: 1219 TTVV--VAHRLSTIKN-ADVIAIV 1239
>7303902 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1344
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/191 (26%), Positives = 96/191 (49%), Gaps = 18/191 (9%)
Query: 364 DFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAP 423
D++L+ E ++ ++G G+GK++LI+ + G + A+ GQ ++S Q+ +
Sbjct: 465 DYTLSGINLEIKPGSVVAVIGLTGSGKSSLIQAILGELKANSGQLQVNGSLSYTSQE-SW 523
Query: 424 KFTGTVRQLFFKRIRAQFLNPQFQTDVVK-----------PLKIDDIIDQEVQHLSGGEL 472
F+GTVRQ + Q ++ Q +VVK PL+ + I+ + LSGG+
Sbjct: 524 LFSGTVRQNI---LFGQPMDSQRYEEVVKKCALERDFDLLPLRDNTIVGERGATLSGGQK 580
Query: 473 QRVAIVLSLGMNADIYLIDEPSAYLD-SEQRIICSKVIRRFILHNKKTAFIVEHDFIMAT 531
R+++ S+ A IYL+D+P + +D S R + + +R + T +V H
Sbjct: 581 ARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHL--RGSTVVLVTHQEQFLP 638
Query: 532 YLADKVIVFDG 542
++ VI+ +G
Sbjct: 639 HVDQIVILANG 649
>7295830 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 609
Score = 58.9 bits (141), Expect = 2e-08
Identities = 66/227 (29%), Positives = 100/227 (43%), Gaps = 24/227 (10%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAG-KQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKM 159
+ G++ ++G +G GKST L LAG K + G+F ++I+ + + S M
Sbjct: 51 KSGRLTAILGPSGAGKSTLLNALAGFKLQGVTGQFLLNGRPRDIMSFRKMSAYIAQNFVM 110
Query: 160 LEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSK--DDAKRYIDILQLKNVLNR 217
L ++ + + +K P + EK K DD IDILQL++
Sbjct: 111 LN-----LLTVEETLRVSTDLKMPSSTAAQ------EKQKIIDDI---IDILQLQSCRRT 156
Query: 218 EVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICV 277
V LSGGE +R +IG+ V + FDEP+S LD ++ L + V+CV
Sbjct: 157 LVKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRIVVCV 216
Query: 278 EHDL-SVLDYLSDFVCIIYGVPSVYGVVTLPSSVREGINIFL-DGHI 322
H S L L D V ++ +G V RE + F GHI
Sbjct: 217 VHQPGSRLFQLFDDVLVL-----AHGEVLYAGEQREMLPTFAQSGHI 258
>At2g36910 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1286
Score = 58.5 bits (140), Expect = 3e-08
Identities = 56/201 (27%), Positives = 94/201 (45%), Gaps = 40/201 (19%)
Query: 353 FTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------ 404
F+YP + +F L+V AG+ + ++G +G+GK+T++ L+ +
Sbjct: 375 FSYPSRPDVKILNNFCLSVPAGK-----TIALVGSSGSGKSTVVSLIERFYDPNSGQVLL 429
Query: 405 DGQDIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRAQFLNPQFQTDVVKP-------- 453
DGQD+ L + Q+I G V Q LF I+ L + D V+
Sbjct: 430 DGQDLKTLKLRWLRQQI-----GLVSQEPALFATSIKENILLGRPDADQVEIEEAARVAN 484
Query: 454 -----LKIDDIIDQEVQH----LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRII 504
+K+ D D +V LSGG+ QR+AI ++ N I L+DE ++ LDSE +
Sbjct: 485 AHSFIIKLPDGFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKL 544
Query: 505 CSKVIRRFILHNKKTAFIVEH 525
+ + RF++ +T I+ H
Sbjct: 545 VQEALDRFMI--GRTTLIIAH 563
>Hs4501849 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1704
Score = 58.2 bits (139), Expect = 4e-08
Identities = 60/246 (24%), Positives = 105/246 (42%), Gaps = 39/246 (15%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
GQ+ L+G NG GK+T L +L G P GR Y G E+ M++
Sbjct: 559 GQITVLLGHNGAGKTTTLSMLTGLFPPTSGR-----------AYISGYEISQ---DMVQI 604
Query: 163 DIKAIIKPQY---VDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREV 219
+ PQ+ DN+ + + +L L +K ++ K+ + I+ L++ N
Sbjct: 605 RKSLGLCPQHDILFDNL--TVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRS 662
Query: 220 SALSGGELQRFAIGMSCVQEADVYMFDEPSSYLD-VKQRLNAALIIRSLLNPTTYVICVE 278
LSGG ++ +IG++ + + V + DEP+S +D + +R L+ R + T ++
Sbjct: 663 RFLSGGMRRKLSIGIALIAGSKVLILDEPTSGMDAISRRAIWDLLQRQKSDRT--IVLTT 720
Query: 279 HDLSVLDYLSDFVCII-----------------YGVPSVYGVVTLPSSVREGINIFLDGH 321
H + D L D + I+ YG +V P E I+ + H
Sbjct: 721 HFMDEADLLGDRIAIMAKGELQCCGSSLFLKQKYGAGYHMTLVKEPHCNPEDISQLVHHH 780
Query: 322 IPSENL 327
+P+ L
Sbjct: 781 VPNATL 786
Score = 51.2 bits (121), Expect = 4e-06
Identities = 43/180 (23%), Positives = 86/180 (46%), Gaps = 18/180 (10%)
Query: 376 DSQILVMMGENGTGKTTLIKLLAGAIPADDG----------QDIPKLNVSMK--PQKIAP 423
+ QI V++G NG GKTT + +L G P G QD+ ++ S+ PQ
Sbjct: 558 EGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIRKSLGLCPQHDIL 617
Query: 424 KFTGTVRQLFFKRIRAQFLNPQFQTDVVKP----LKIDDIIDQEVQHLSGGELQRVAIVL 479
TV + + + + L+ Q + VK + ++D + + LSGG ++++I +
Sbjct: 618 FDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIGI 677
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+L + + ++DEP++ +D+ R +++R + +T + H A L D++ +
Sbjct: 678 ALIAGSKVLILDEPTSGMDAISRRAIWDLLQR--QKSDRTIVLTTHFMDEADLLGDRIAI 735
>CE05221 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1283
Score = 58.2 bits (139), Expect = 4e-08
Identities = 58/211 (27%), Positives = 98/211 (45%), Gaps = 34/211 (16%)
Query: 354 TYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DGQ 407
T PD+ + + S V+ GE + ++G +G+GK+T+I+LL D DG
Sbjct: 416 TRPDVPVLK-EISFNVQGGE-----CIALVGASGSGKSTVIQLLLHYYNIDSGRISIDGN 469
Query: 408 DIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRA--QFLNPQF-QTDVVKPLK--------- 455
DI +N+ Q + F V LF I +F P + +++ LK
Sbjct: 470 DIYNINIKQLRQAMGVVFQEPV--LFNTSIEENIRFGKPDATEQEIIDALKNANAFDFVC 527
Query: 456 -----IDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIR 510
I I+ + LSGG+ QR+AI +L N I L+DE ++ LD+E I + ++
Sbjct: 528 NFPDGIKTIVGERGAQLSGGQKQRIAIARTLVRNPRILLLDEATSALDNESEFIVQEALQ 587
Query: 511 RFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
+ + +T +V H + A+K+IV +
Sbjct: 588 KASI--GRTTIVVAHR-LSTIRNANKIIVME 615
>7296045 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 627
Score = 58.2 bits (139), Expect = 4e-08
Identities = 48/204 (23%), Positives = 88/204 (42%), Gaps = 27/204 (13%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
R G++ ++G +G GKST L +++G G+ + P + I + Y + +
Sbjct: 139 RSGELTAIMGPSGAGKSTLLNVMSGFCNGRGGKDDAPGGTRVFIA-------KRYRSTGV 191
Query: 161 EDDIKAIIKPQ--------------YVDNI--PRAIKGPVQKVGELLKLRLEKSK----D 200
DI+ KP + D++ P+ + G + + LKL + +K D
Sbjct: 192 SGDIRVNRKPMAPSSERFRQMLCYIHQDDLLRPQLLVGEIMLLAAHLKLGFKVTKAYKMD 251
Query: 201 DAKRYIDILQLKNVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNA 260
K + +L L + N LSGG+ +R AI + + V DEP++ LD +
Sbjct: 252 LIKHILSLLGLDHRYNVPTGKLSGGQKKRLAIALELISNPPVLYLDEPTTGLDSSSCSSC 311
Query: 261 ALIIRSLLNPTTYVICVEHDLSVL 284
+++ L + ++C H S L
Sbjct: 312 VALLKKLASQGHTIVCTIHQPSAL 335
>Hs4505769 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1279
Score = 57.8 bits (138), Expect = 5e-08
Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 31/212 (14%)
Query: 353 FTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL------AGAIPAD 404
F+YP K + +L V++G Q + ++G +G GK+T ++L+ + +
Sbjct: 398 FSYPSRKEVKILKGLNLKVQSG-----QTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSV 452
Query: 405 DGQDIPKLNV----------SMKPQKIAPKFTGTVR----QLFFKRIRAQFLNPQFQTDV 450
DGQDI +NV S +P A +R + I +
Sbjct: 453 DGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFI 512
Query: 451 VK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVI 509
+K P K D ++ + LSGG+ QR+AI +L N I L+DE ++ LD+E + +
Sbjct: 513 MKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVAL 572
Query: 510 RRFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
+ +T ++ H + AD + FD
Sbjct: 573 DK--ARKGRTTIVIAHR-LSTVRNADVIAGFD 601
>At1g02520 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1278
Score = 57.8 bits (138), Expect = 5e-08
Identities = 53/202 (26%), Positives = 88/202 (43%), Gaps = 37/202 (18%)
Query: 352 AFTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD----- 404
+FTYP Q D LT+ AG+ + ++GE+G+GK+T+I LL D
Sbjct: 1038 SFTYPARPDIQIFRDLCLTIRAGK-----TVALVGESGSGKSTVISLLQRFYDPDSGHIT 1092
Query: 405 -DGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKI------- 456
DG ++ KL + Q++ G LF IRA + + +I
Sbjct: 1093 LDGVELKKLQLKWLRQQMG--LVGQEPVLFNDTIRANIAYGKGSEEAATESEIIAAAELA 1150
Query: 457 -------------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRI 503
D ++ + LSGG+ QRVAI ++ I L+DE ++ LD+E
Sbjct: 1151 NAHKFISSIQQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESER 1210
Query: 504 ICSKVIRRFILHNKKTAFIVEH 525
+ + R +++ +T +V H
Sbjct: 1211 VVQDALDRVMVN--RTTIVVAH 1230
Score = 50.8 bits (120), Expect = 6e-06
Identities = 56/194 (28%), Positives = 89/194 (45%), Gaps = 22/194 (11%)
Query: 99 TPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTK 158
T R G+ + LVG +G GKST + +L RF DP + G EL+ K
Sbjct: 1056 TIRAGKTVALVGESGSGKSTVISLLQ--------RFYDPDSGHITLD---GVELKKLQLK 1104
Query: 159 MLEDDIKAI-IKPQYVDNIPRAI----KGPVQKVGELLKLRLEKSKDDAKRYIDILQ--L 211
L + + +P ++ RA KG + E ++ +A ++I +Q
Sbjct: 1105 WLRQQMGLVGQEPVLFNDTIRANIAYGKGSEEAATES-EIIAAAELANAHKFISSIQQGY 1163
Query: 212 KNVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNP 270
V+ LSGG+ QR AI + V+E + + DE +S LD + +R+ + R ++N
Sbjct: 1164 DTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNR 1223
Query: 271 TTYVICVEHDLSVL 284
TT I V H LS +
Sbjct: 1224 TT--IVVAHRLSTI 1235
Score = 50.4 bits (119), Expect = 8e-06
Identities = 53/202 (26%), Positives = 92/202 (45%), Gaps = 28/202 (13%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G LVG +G GKST + ++ RF DP +I G L+ + K +
Sbjct: 409 GATAALVGESGSGKSTVISLIE--------RFYDPKSGAVLID---GVNLKEFQLKWIRS 457
Query: 163 DI------KAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQ--LKNV 214
I + ++NI G E +K E + +A ++ID L L +
Sbjct: 458 KIGLVSQEPVLFSSSIMENIAY---GKENATVEEIKAATELA--NAAKFIDKLPQGLDTM 512
Query: 215 LNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTTY 273
+ + LSGG+ QR AI + +++ + + DE +S LD + +R+ + R ++N TT
Sbjct: 513 VGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRVMVNRTT- 571
Query: 274 VICVEHDLSVLDYLSDFVCIIY 295
+ V H LS + +D + +I+
Sbjct: 572 -VIVAHRLSTVRN-ADMIAVIH 591
>7298089 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 324
Score = 57.8 bits (138), Expect = 5e-08
Identities = 44/178 (24%), Positives = 84/178 (46%), Gaps = 15/178 (8%)
Query: 375 SDSQILVMMGENGTGKTTLIKLLAGAIPADDG-------QDIPKLN--VSMKPQKIAPKF 425
++ +I V++G NG GKTT++ ++ G +P D G +D+ + PQ
Sbjct: 45 NNKEITVLLGHNGAGKTTMMNMIMGLVPKDSGKIIVCSERDVASYRHLIGFCPQHSVFMS 104
Query: 426 TGTVRQ--LFFKRIRAQFLNP--QFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSL 481
T Q FF ++R + + + +K L + D ++ ++LSGG +R+++ +++
Sbjct: 105 YMTCHQHLEFFAQLRGACRSDARDWADEKLKKLGLSDKRNEFGKNLSGGMKRRLSLGIAI 164
Query: 482 GMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
N I ++DEPS+ LD R ++ L +K + H A L D + +
Sbjct: 165 AGNTKIVILDEPSSGLDINSRRELWDILLN--LRKEKAVLVTTHYMEEAEVLGDTICI 220
>7293943 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1463
Score = 57.8 bits (138), Expect = 5e-08
Identities = 51/183 (27%), Positives = 85/183 (45%), Gaps = 24/183 (13%)
Query: 376 DSQILVMMGENGTGKTTLIKLLAGAIPADDGQDI------------PKLNVSMKPQK-IA 422
+ QI V+MG NG GKTTLI +LAG I G + + + + PQ+ +
Sbjct: 363 EGQITVLMGHNGAGKTTLISMLAGFISPTSGTALINGFDIRQERRQAQRCIGLCPQQNVL 422
Query: 423 PKFTGTVRQL-FFKRIRAQFLNPQFQTDV---VKPLKIDDIIDQEVQHLSGGELQRVAIV 478
K +V + F R+R + +++V +K L + + ++LSGG +R+++
Sbjct: 423 FKHLSSVSHIQLFSRLRG-LRGAEVKSEVQNYLKKLNLQEKKRLAARNLSGGTQRRLSVA 481
Query: 479 LSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKK--TAFIVEHDFIMATYLADK 536
SL + + DEPS LD R + + R IL K+ T + H L D+
Sbjct: 482 CSLCGGVKVLICDEPSTGLDPSAR----RELWRLILEAKEGCTILLTTHQLDDGEVLGDR 537
Query: 537 VIV 539
V++
Sbjct: 538 VVI 540
>Hs6005701 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1581
Score = 57.4 bits (137), Expect = 6e-08
Identities = 50/197 (25%), Positives = 91/197 (45%), Gaps = 22/197 (11%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
R G+VLGL+G NG GKST++K++ G KP G Q ++K G + +
Sbjct: 1274 RKGEVLGLLGHNGAGKSTSIKVITGDTKPTAG--------QVLLKGSGGGDALEFLGYCP 1325
Query: 161 EDDI--KAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNRE 218
+++ + Q+++ + A+KG LR ++ R +D L+L++ L
Sbjct: 1326 QENALWPNLTVRQHLE-VYAAVKG----------LRKGDAEVAITRLVDALKLQDQLKSP 1374
Query: 219 VSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL-NPTTYVICV 277
V LS G ++ +S + V + DEPS+ +D + + IR+ N +
Sbjct: 1375 VKTLSEGIKRKLCFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLT 1434
Query: 278 EHDLSVLDYLSDFVCII 294
H ++ + + D V I+
Sbjct: 1435 THYMAEAEAVCDRVAIM 1451
Score = 55.1 bits (131), Expect = 3e-07
Identities = 48/174 (27%), Positives = 80/174 (45%), Gaps = 12/174 (6%)
Query: 378 QILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLN--------VSMKPQKIAPKFTGTV 429
++L ++G NG GK+T IK++ G GQ + K + + PQ+ A TV
Sbjct: 1277 EVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQENALWPNLTV 1336
Query: 430 RQLFFKRIRAQFLNPQFQ----TDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNA 485
RQ + L T +V LK+ D + V+ LS G +++ VLS+ N
Sbjct: 1337 RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNP 1396
Query: 486 DIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ L+DEPS +D E + + IR + ++ A + H A + D+V +
Sbjct: 1397 SVVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1450
>Hs17865630 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1642
Score = 57.0 bits (136), Expect = 8e-08
Identities = 61/253 (24%), Positives = 104/253 (40%), Gaps = 39/253 (15%)
Query: 56 IGCGICVKKCPFDAIQIINLPTNLDSQVTHRYSANSFKLHRLPTP------RPGQVLGLV 109
+GC C +K +I + NL D + S K+ ++ T + G++LGL+
Sbjct: 1279 MGCQCCEEK---PSIMVSNLHKEYDDKKDFLLSR---KVKKVATKYISFCVKKGEILGLL 1332
Query: 110 GTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDD--IKAI 167
G NG GKST + IL G +P G+ L +Y ++ EDD +K +
Sbjct: 1333 GPNGAGKSTIINILVGDIEPTSGQV----------------FLGDYSSETSEDDDSLKCM 1376
Query: 168 -----IKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSAL 222
I P + D ++ + G + + K+ R L LK L + V L
Sbjct: 1377 GYCPQINPLWPDT---TLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKL 1433
Query: 223 SGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL-NPTTYVICVEHDL 281
G ++ +S + + + DEPS+ +D K + + IR+ N I H +
Sbjct: 1434 PAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYM 1493
Query: 282 SVLDYLSDFVCII 294
+ + D V I+
Sbjct: 1494 EEAEAVCDRVAIM 1506
Score = 54.3 bits (129), Expect = 5e-07
Identities = 52/188 (27%), Positives = 91/188 (47%), Gaps = 23/188 (12%)
Query: 376 DSQILVMMGENGTGKTTLIKLLAGAIPADDG---------QDIPKLNVSMKPQKIAPKF- 425
+ QI ++G +GTGK+TL+ +L G P DG +I ++ + K I P+
Sbjct: 506 EGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLD 565
Query: 426 ----TGTVRQ-----LFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVA 476
TV + K I A + + Q V+ L + I D + + LSGG+ ++++
Sbjct: 566 IHFDVLTVEENLSILASIKGIPANNIIQEVQ-KVLLDLDMQTIKDNQAKKLSGGQKRKLS 624
Query: 477 IVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLAD- 535
+ +++ N I L+DEP+A +D R I ++ ++ N+ T F H A LAD
Sbjct: 625 LGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLL-KYRKANRVTVFST-HFMDEADILADR 682
Query: 536 KVIVFDGI 543
K ++ G+
Sbjct: 683 KAVISQGM 690
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/179 (25%), Positives = 79/179 (43%), Gaps = 17/179 (9%)
Query: 378 QILVMMGENGTGKTTLIKLLAGAIPADDGQ------------DIPKLNVSMKPQKIAPKF 425
+IL ++G NG GK+T+I +L G I GQ D L +I P +
Sbjct: 1327 EILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLW 1386
Query: 426 TGTVRQLFFKRIRA-QFLNPQFQTDVVK----PLKIDDIIDQEVQHLSGGELQRVAIVLS 480
T Q F+ A + ++ +V+ L + + + + V+ L G +++ LS
Sbjct: 1387 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALS 1446
Query: 481 LGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ N I L+DEPS +D + + + IR + K+ A + H A + D+V +
Sbjct: 1447 MLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAI 1505
>7295821 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 729
Score = 57.0 bits (136), Expect = 8e-08
Identities = 49/182 (26%), Positives = 83/182 (44%), Gaps = 33/182 (18%)
Query: 371 AGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTV- 429
+G S ++L +MG +G+GKTTL+ L+G D G +V + + + K+ +
Sbjct: 84 SGFVSPCEVLAIMGPSGSGKTTLLDCLSGQRHIDSG------SVFLNREPLTKKWRRRIG 137
Query: 430 ----RQLFFKRIR--------AQFLNPQFQTDVVKPLKIDDIID-------QEVQH---- 466
++FF ++ A P+ K ++D I++ Q+ +
Sbjct: 138 YVLQEEIFFPQLTLRETVVYTALLRLPESMPRAEKMRQVDHILEALELGCCQQTKFGDYL 197
Query: 467 ---LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIV 523
LSGGE +R I L N + L+DEP++ LDS I KV++R+ +KT I
Sbjct: 198 NRGLSGGEKKRANIACELLTNPLLMLLDEPTSGLDSHSAISLMKVLKRYAQLEQKTIVIS 257
Query: 524 EH 525
H
Sbjct: 258 VH 259
>YFR009w [EJ] KOG0062 ATPase component of ABC transporters with duplicated
ATPase domains/Translation elongation factor EF-3b
Length = 752
Score = 56.6 bits (135), Expect = 1e-07
Identities = 46/181 (25%), Positives = 80/181 (43%), Gaps = 31/181 (17%)
Query: 106 LGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIK 165
+ LVG NG GK+T LKI+ + +P G P + YFT+ D +
Sbjct: 561 IALVGANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRI-----------GYFTQHHVDSMD 609
Query: 166 AIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLN-REVSALSG 224
+ VD + ++ G K+ ++ +R++ + L +++ LSG
Sbjct: 610 --LTTSAVDWMSKSFPG--------------KTDEEYRRHLGSFGITGTLGLQKMQLLSG 653
Query: 225 GELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVL 284
G+ R A C+ + + DEPS++LD ++ +L N V+ V HD+SV+
Sbjct: 654 GQKSRVAFAALCLNNPHILVLDEPSNHLDT---TGLDALVEALKNFNGGVLMVSHDISVI 710
Query: 285 D 285
D
Sbjct: 711 D 711
>Hs4557481 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1545
Score = 56.6 bits (135), Expect = 1e-07
Identities = 64/258 (24%), Positives = 118/258 (44%), Gaps = 39/258 (15%)
Query: 342 GDELEADASR--------------AFTYP-DMKRTQGDFSLTVEAGEFSDSQILVMMGEN 386
GD+L+ A R +FT+ D + T D +L + AG Q++ ++G
Sbjct: 619 GDDLDTSAIRHDCNFDKAMQFSEASFTWEHDSEATVRDVNLDIMAG-----QLVAVIGPV 673
Query: 387 GTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQF 446
G+GK++LI + G + G K + PQ+ + GT++ +F ++
Sbjct: 674 GSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQ-NGTIKDNIL--FGTEFNEKRY 730
Query: 447 QTDVVKPLKIDDI----------IDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAY 496
Q + + D+ I ++ +LSGG+ QR+++ + N DIYL+D+P +
Sbjct: 731 QQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSA 790
Query: 497 LDSE-QRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDG-IPSKQAFARAPE 554
+D+ + I +KV+ L KT +V H + + V++ +G I K +++
Sbjct: 791 VDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYS---- 846
Query: 555 SLLTGCNKFLKNLNVTFR 572
+LL +F KNL R
Sbjct: 847 ALLAKKGEFAKNLKTFLR 864
>Hs17933762 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1624
Score = 56.6 bits (135), Expect = 1e-07
Identities = 49/174 (28%), Positives = 81/174 (46%), Gaps = 12/174 (6%)
Query: 378 QILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLN--------VSMKPQKIAPKFTGTV 429
+++ ++G NG GK+T IK++ G GQ I K + + PQ+ A TV
Sbjct: 1320 EVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTV 1379
Query: 430 RQLFFKRIRAQFLNPQFQ----TDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNA 485
RQ + L T +V LK+ D + V+ LS G +++ VLS+ N
Sbjct: 1380 RQHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKLRFVLSILGNP 1439
Query: 486 DIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ L+DEPS +D E + +VIR + ++ A + H A + D+V +
Sbjct: 1440 SVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1493
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/197 (25%), Positives = 90/197 (45%), Gaps = 22/197 (11%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
+ G+V+GL+G NG GKST +K++ G KP G Q I+K G E +
Sbjct: 1317 KKGEVIGLLGHNGAGKSTTIKMITGDTKPTAG--------QVILKGSGGGEPLGFLGYCP 1368
Query: 161 EDDI--KAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNRE 218
+++ + Q+++ + A+KG LR + R +D L+L++ L
Sbjct: 1369 QENALWPNLTVRQHLE-VYAAVKG----------LRKGDAMIAITRLVDALKLQDQLKAP 1417
Query: 219 VSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL-NPTTYVICV 277
V LS G ++ +S + V + DEPS+ +D + + +IR+ N +
Sbjct: 1418 VKTLSEGIKRKLRFVLSILGNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLT 1477
Query: 278 EHDLSVLDYLSDFVCII 294
H ++ + + D V I+
Sbjct: 1478 THYMAEAEAVCDRVAIM 1494
Score = 50.4 bits (119), Expect = 8e-06
Identities = 57/192 (29%), Positives = 96/192 (49%), Gaps = 33/192 (17%)
Query: 376 DSQILVMMGENGTGKTTLIKLLAG-AIPADDGQDIPKLNVS-MKPQKIAPKFTG------ 427
+ QI ++G +G GKTTL+ +L+G ++P + +S M + KFTG
Sbjct: 509 EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSN 568
Query: 428 ------TVRQ---LF--FKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVA 476
TV++ LF K I + + Q VV+ L++++I D Q+LSGG+ +++
Sbjct: 569 VQFGFLTVKENLRLFAKIKGILPHEVEKEVQR-VVQELEMENIQDILAQNLSGGQNRKLT 627
Query: 477 IVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIR-----RFILHNKKTAFIVEHDFIMAT 531
+++ + + L+DEP+A LD R +++ R IL + T FI E D
Sbjct: 628 FGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFS--TQFIDEADI---- 681
Query: 532 YLAD-KVIVFDG 542
LAD KV + +G
Sbjct: 682 -LADRKVFISNG 692
>At5g13580 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 727
Score = 56.6 bits (135), Expect = 1e-07
Identities = 53/205 (25%), Positives = 89/205 (42%), Gaps = 31/205 (15%)
Query: 372 GEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVRQ 431
GE D +IL ++G +G+GK+TLI LA I + LN + K+ + V Q
Sbjct: 114 GEARDGEILAVLGASGSGKSTLIDALANRIAKGSLKGNVTLNGEVLNSKMQKAISAYVMQ 173
Query: 432 --LFFKRIR--------AQFLNPQFQTDVVKPLKIDDIIDQ------------EVQH--L 467
L F + A+F P+ + K L++ +IDQ + H +
Sbjct: 174 DDLLFPMLTVEETLMFAAEFRLPRSLSKSKKSLRVQALIDQLGLRNAANTVIGDEGHRGI 233
Query: 468 SGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDF 527
SGGE +RV+I + + + + +DEP++ LDS + KV++R +
Sbjct: 234 SGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSALSVIKVLKRIAQSGSMVIMTLHQPS 293
Query: 528 IMATYLADKVI-------VFDGIPS 545
L D+++ VF G P+
Sbjct: 294 YRLLRLLDRLLFLSRGQTVFSGSPA 318
>At5g09930 [R] KOG0927 Predicted transporter (ABC superfamily)
Length = 674
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/209 (23%), Positives = 99/209 (46%), Gaps = 29/209 (13%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQE--IIKYFRGSELQNYFTK 158
+ G+ +GL+G NG GK+T L+I+ G+++P+ G W + + F E + K
Sbjct: 107 KKGEKVGLIGVNGAGKTTQLRIITGQEEPDSGNV----IWAKPNLKVAFLSQEFEVSMGK 162
Query: 159 MLEDDIKAIIKPQY-----VDNIPRAIKGPV---QKVGELLK-----LRLEKSKDDAKRY 205
++++ K + ++N+ +AI+ V + +G+LL R + D +
Sbjct: 163 TVKEEFMCTFKEEMEIARKLENLQKAIEEAVDDLELMGKLLDEFDLLQRRAQEVDLDSIH 222
Query: 206 IDILQLKNVL-------NREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRL 258
I +L + L +R V++ S G R ++G +Q D+ + DEP+++LD+
Sbjct: 223 AKISKLMSELGFVSEDADRLVASFSSGWQMRMSLGKILLQNPDLLLLDEPTNHLDLD--- 279
Query: 259 NAALIIRSLLNPTTYVICVEHDLSVLDYL 287
+ L+ ++ + HD + LD L
Sbjct: 280 TIEWLEGYLIKQDVPMVIISHDRAFLDQL 308
>CE15714 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1294
Score = 56.2 bits (134), Expect = 1e-07
Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 39/214 (18%)
Query: 353 FTYP---DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ-- 407
FTYP D+K +G SL + G Q + ++G +G GK+T+I+LL D GQ
Sbjct: 390 FTYPTRADVKILKG-VSLDAQPG-----QTVALVGSSGCGKSTIIQLLQRFYNPDAGQIL 443
Query: 408 --DIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIR---------------AQFLNPQFQ 447
DIP + ++K + + G V Q LF I A+ L
Sbjct: 444 IDDIPIEDFNIKYLR---QLVGVVSQEPNLFNTSIEQNIRYGRSDVSDEDIARALKEANA 500
Query: 448 TDVVK--PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIIC 505
D +K P ++ ++ +SGG+ QR+AI +L N I L+DE ++ LD+E I
Sbjct: 501 ADFIKTFPEGLNTLVGDRGVQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESESIV 560
Query: 506 SKVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ +T ++ H + ADK+IV
Sbjct: 561 QSALEN--ASRGRTTIVIAHR-LSTVRNADKIIV 591
Score = 53.9 bits (128), Expect = 7e-07
Identities = 49/191 (25%), Positives = 85/191 (43%), Gaps = 23/191 (12%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGR--FEDPPEWQEIIKYFRG-----SELQ 153
+PGQ + LVG++G GKST +++L P+ G+ +D P IKY R S+
Sbjct: 409 QPGQTVALVGSSGCGKSTIIQLLQRFYNPDAGQILIDDIPIEDFNIKYLRQLVGVVSQEP 468
Query: 154 NYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKN 213
N F +E +I+ ++I RA+K + D K + + L
Sbjct: 469 NLFNTSIEQNIRYGRSDVSDEDIARALKE-------------ANAADFIKTFPE--GLNT 513
Query: 214 VLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTY 273
++ +SGG+ QR AI + V+ + + DE +S LD + + + T
Sbjct: 514 LVGDRGVQMSGGQKQRIAIARALVRNPKILLLDEATSALDAESESIVQSALENASRGRTT 573
Query: 274 VICVEHDLSVL 284
++ + H LS +
Sbjct: 574 IV-IAHRLSTV 583
Score = 50.8 bits (120), Expect = 6e-06
Identities = 50/189 (26%), Positives = 84/189 (43%), Gaps = 17/189 (8%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
+PGQ L LVG +G GKST + +L R DP E + ++L+ K L
Sbjct: 1056 KPGQTLALVGPSGCGKSTVISLLE--------RLYDPLEGAVTVD---NNDLRQMNPKHL 1104
Query: 161 EDDIKAII-KPQYVDNIPRAIKGPVQKVGELLKLRLEK--SKDDAKRYIDILQ--LKNVL 215
I + +P D R + GE ++E SK + ++ID L + +
Sbjct: 1105 RKHIALVSQEPILFDTSIRENIVYGLQPGEYTHEQIETACSKANIHKFIDELPDGYETRV 1164
Query: 216 NREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVI 275
+ + LSGG+ QR AI + ++ + + DE +S LD + + + + T ++
Sbjct: 1165 GEKGTQLSGGQKQRIAIARALIRNPKILLLDEATSALDTESEKQVQVALDAAAKDRTCIV 1224
Query: 276 CVEHDLSVL 284
V H LS +
Sbjct: 1225 -VAHRLSTI 1232
>7300555 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1348
Score = 56.2 bits (134), Expect = 1e-07
Identities = 52/195 (26%), Positives = 94/195 (47%), Gaps = 17/195 (8%)
Query: 357 DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSM 416
D K T D +L + +F Q++ ++G G+GK++LI+ + G + D G K+N ++
Sbjct: 453 DQKNT--DNTLDNISLKFKPRQLVAVIGPVGSGKSSLIQAVLGELNPDSGS--VKVNGTL 508
Query: 417 KPQKIAP-KFTGTVRQLFF-------KRIRAQFLNPQFQTDV-VKPLKIDDIIDQEVQHL 467
P FTGTVRQ R R + D + P I+ + L
Sbjct: 509 SYASQEPWLFTGTVRQNILFGLPMDKHRYRTVVKRCALERDFELLPYADKTIVGERGASL 568
Query: 468 SGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE-QRIICSKVIRRFILHNKKTAFIVEHD 526
SGG+ R+++ ++ ADIYL+D+P + +D+ R + + +R F+ ++ +V H
Sbjct: 569 SGGQKARISLARAVYRKADIYLLDDPLSAVDTHVGRHLFDQCMRGFL--REEIVLLVTHQ 626
Query: 527 FIMATYLADKVIVFD 541
+ AD +++ D
Sbjct: 627 -LQFLEQADVIVIMD 640
>At2g39350 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 740
Score = 55.8 bits (133), Expect = 2e-07
Identities = 46/165 (27%), Positives = 78/165 (46%), Gaps = 24/165 (14%)
Query: 371 AGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVR 430
+GE D +I+ ++G +G+GK+TLI LA I + KLN ++ + V
Sbjct: 114 SGETRDGEIMAVLGASGSGKSTLIDALANRIAKGSLKGTVKLNGETLQSRMLKVISAYVM 173
Query: 431 Q--LFFKRI--------RAQFLNPQFQTDVVKPLKIDDIIDQ------------EVQH-- 466
Q L F + A+F P+ K L++ +IDQ + H
Sbjct: 174 QDDLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIRNAAKTIIGDEGHRG 233
Query: 467 LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRR 511
+SGGE +RV+I + + + + +DEP++ LDS + KV++R
Sbjct: 234 ISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSAFMVVKVLKR 278
>Hs8051577 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 662
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 17/182 (9%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G+++ ++G +G GKST + ILAG ++ + ++ FR ++ Y +++D
Sbjct: 107 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFR--KVSCY---IMQD 161
Query: 163 DIKAIIKPQYVDNIPRAIKGPVQKVGELLKL--RLEKSKDDAKRYIDILQLKNVLNREVS 220
D+ +P V LKL + E ++ K + L L + N
Sbjct: 162 DML----------LPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTG 211
Query: 221 ALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHD 280
+LSGG+ +R AI + V V FDEP+S LD +++ L +IC H
Sbjct: 212 SLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQ 271
Query: 281 LS 282
S
Sbjct: 272 PS 273
>Hs8051575 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 674
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 17/182 (9%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G+++ ++G +G GKST + ILAG ++ + ++ FR ++ Y +++D
Sbjct: 107 GELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFR--KVSCY---IMQD 161
Query: 163 DIKAIIKPQYVDNIPRAIKGPVQKVGELLKL--RLEKSKDDAKRYIDILQLKNVLNREVS 220
D+ +P V LKL + E ++ K + L L + N
Sbjct: 162 DML----------LPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTG 211
Query: 221 ALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHD 280
+LSGG+ +R AI + V V FDEP+S LD +++ L +IC H
Sbjct: 212 SLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQ 271
Query: 281 LS 282
S
Sbjct: 272 PS 273
>At4g01830 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1230
Score = 55.5 bits (132), Expect = 2e-07
Identities = 52/202 (25%), Positives = 93/202 (45%), Gaps = 38/202 (18%)
Query: 352 AFTY---PDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD---- 404
+FTY PD++ + D L++ AG Q + ++GE+G+GK+T+I LL D
Sbjct: 991 SFTYQTRPDVQVFR-DLCLSIRAG-----QTVALVGESGSGKSTVISLLQRFYDPDSGHI 1044
Query: 405 --DGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFL-----NPQFQTDVVKPLKI- 456
DG ++ KL + Q++ G LF IRA + +++ ++
Sbjct: 1045 TLDGVELKKLRLKWLRQQMG--LVGQEPVLFNDTIRANIAYGKGGEEATEAEIIAASELA 1102
Query: 457 -------------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRI 503
D ++ + LSGG+ QRVAI ++ I L+DE ++ LD+E
Sbjct: 1103 NAHRFISSIQKGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESER 1162
Query: 504 ICSKVIRRFILHNKKTAFIVEH 525
+ + R +++ +T +V H
Sbjct: 1163 VVQDALDRVMVN--RTTIVVAH 1182
Score = 54.7 bits (130), Expect = 4e-07
Identities = 54/203 (26%), Positives = 97/203 (47%), Gaps = 30/203 (14%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G LVG +G GKST + ++ RF DP Q +I G +L+ + K +
Sbjct: 381 GTTTALVGESGSGKSTVISLIE--------RFYDPNSGQVLID---GVDLKEFQLKWIRG 429
Query: 163 DI------KAIIKPQYVDNIPRAIKGP-VQKVGELLKLRLEKSKDDAKRYIDILQL--KN 213
I + ++NI +G V+++ KL +A ++ID L L +
Sbjct: 430 KIGLVSQEPVLFSSSIMENIGYGKEGATVEEIQAASKLA------NAAKFIDKLPLGLET 483
Query: 214 VLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTT 272
++ + LSGG+ QR AI + +++ + + DE +S LD + +R+ + R ++N TT
Sbjct: 484 LVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTT 543
Query: 273 YVICVEHDLSVLDYLSDFVCIIY 295
+ V H LS + +D + +I+
Sbjct: 544 --VIVAHRLSTVRN-ADIIAVIH 563
Score = 54.7 bits (130), Expect = 4e-07
Identities = 61/220 (27%), Positives = 97/220 (43%), Gaps = 19/220 (8%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFE-DPPEWQEI-IKYFRGSE-LQNYFT 157
R GQ + LVG +G GKST + +L P+ G D E +++ +K+ R L
Sbjct: 1011 RAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLRLKWLRQQMGLVGQEP 1070
Query: 158 KMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQ--LKNVL 215
+ D I+A I Y A + + EL +A R+I +Q V+
Sbjct: 1071 VLFNDTIRANIA--YGKGGEEATEAEIIAASELA---------NAHRFISSIQKGYDTVV 1119
Query: 216 NREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTTYV 274
LSGG+ QR AI + V+E + + DE +S LD + +R+ + R ++N TT
Sbjct: 1120 GERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTT-- 1177
Query: 275 ICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPSSVREGI 314
I V H LS + + GV + G ++ G+
Sbjct: 1178 IVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLINIEGGV 1217
>7295352 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1320
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 31/205 (15%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
GQ + LVG +G GKST +++L RF DP Q ++ G +++ Y K L
Sbjct: 442 GQTVALVGPSGCGKSTCIQLLQ--------RFYDPVFGQVLLD---GEDVRKYNIKWLRS 490
Query: 163 DIKAIIKPQYV------DNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLN 216
+I + + + +NI QK +E + A + I+ L +
Sbjct: 491 NIAVVGQEPVLFQGSIGENIRHGKPEATQK-------EVEDAAKAANAHDFIIALHKGYD 543
Query: 217 REVSA----LSGGELQRFAIGMSCVQEADVYMFDEPSSYLDV-KQRLNAALIIRSLLNPT 271
++S LSGG+ QR AI + +Q+ + + DE +S LD ++L A + ++ T
Sbjct: 544 TDISEKGVQLSGGQRQRIAIARALIQQPKILLLDEATSALDYHSEKLVQAALDKACKGRT 603
Query: 272 TYVICVEHDLSVLDYLSDFVCIIYG 296
T V V H LS + + V I G
Sbjct: 604 TLV--VSHRLSAIRHAHRIVYIENG 626
Score = 52.0 bits (123), Expect = 3e-06
Identities = 51/201 (25%), Positives = 94/201 (46%), Gaps = 25/201 (12%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEII---KYFRGSELQNYFTKM 159
GQ + LVG +G GKST +++L R+ DP E + +I +L+ ++
Sbjct: 1104 GQTVALVGASGSGKSTCVQLLM--------RYYDPDEGKILIDQESIHHDMDLKTLRRRL 1155
Query: 160 -LEDDIKAIIKPQYVDNI---PRAIKGPVQKVGELLKLRLEKSKDDAKRYIDIL--QLKN 213
+ ++ + DNI + + P+Q++ E K+ +A +I L Q
Sbjct: 1156 GIVSQEPSLFEKSIADNIGYGDTSRQVPMQQIIEAAKMA------NAHEFIMSLPAQYDT 1209
Query: 214 VLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTY 273
VL + + LSGG+ QR AI + V+ + + DE +S LD + + S + T
Sbjct: 1210 VLGSKGTQLSGGQKQRIAIARAMVRNPKILLLDEATSALDFQSERVVQQALDSACSGRTC 1269
Query: 274 VICVEHDLSVLDYLSDFVCII 294
++ + H LS + ++ +C+I
Sbjct: 1270 IV-IAHRLSTIQN-ANVICVI 1288
>CE20234 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1802
Score = 55.1 bits (131), Expect = 3e-07
Identities = 45/198 (22%), Positives = 92/198 (45%), Gaps = 27/198 (13%)
Query: 359 KRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ----------D 408
KR + +L + G Q V++G NG GK+T +L G G
Sbjct: 612 KRAVSNLNLKMYPG-----QCTVLLGHNGAGKSTTFSMLTGVASPSSGSAYVNDFDIRTS 666
Query: 409 IPKLNVSMKPQKIAPKFTG-----TVRQL--FFKRIRAQFLNPQFQTDVVKPLKIDDIID 461
+PK+ M + P++ TV + FF +++ + +P+ +++ L+ID D
Sbjct: 667 LPKIRREMG---LCPQYNTLFGFMTVMEHLEFFAKLKERTWDPEEAREILARLRIDFKAD 723
Query: 462 QEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAF 521
LSGG+ +++++ ++L +++ ++DEP++ +D R +I+R ++T
Sbjct: 724 FMAGALSGGQKRKLSLAIALIGGSEVVMLDEPTSGMDPGARHETWTLIQR--EKERRTIL 781
Query: 522 IVEHDFIMATYLADKVIV 539
+ H A L D++ +
Sbjct: 782 LTTHFMEEADLLGDRIAI 799
Score = 54.3 bits (129), Expect = 5e-07
Identities = 49/200 (24%), Positives = 90/200 (44%), Gaps = 20/200 (10%)
Query: 107 GLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDDIKA 166
GL+G NG GK++ ++L G+ + G Y G ++N + E
Sbjct: 1479 GLLGVNGAGKTSTFQMLTGENSISSGD-----------AYVNGWSVKNNWR---EAGANT 1524
Query: 167 IIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNV---LNREVSALS 223
PQY D I + + G + + ++R KD K+ ++ + +R++ S
Sbjct: 1525 GYCPQY-DAIIKEMSGE-ETLYMFARIRGIPEKDIPKKVNAVIHAIGIGMYASRQIKTYS 1582
Query: 224 GGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSV 283
GG +R ++G++ V DV + DEP+S +D K R I+ L + T ++ H +
Sbjct: 1583 GGNKRRLSLGIAIVGLPDVLLLDEPTSGVDPKARRIIWNILNRLRDLGTALVLTSHSMDE 1642
Query: 284 LDYL-SDFVCIIYGVPSVYG 302
+ L ++ ++YG YG
Sbjct: 1643 CEALCTELAIMVYGKFRCYG 1662
>At5g14100 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 278
Score = 55.1 bits (131), Expect = 3e-07
Identities = 50/184 (27%), Positives = 86/184 (46%), Gaps = 32/184 (17%)
Query: 381 VMMGENGTGKTTLIKLLAGAIP-----------ADDGQDIPKLNVSMKP-QKIAPKFTGT 428
++ G++G+GKTTL++LLAG DDGQ PK + + P +K+ F
Sbjct: 82 LIFGKSGSGKTTLLQLLAGLNKPTSGSICIQGYGDDGQ--PKADPDLLPTEKVGIVFQFP 139
Query: 429 VRQLFFKRIRAQF------------LNPQFQTDVVKPLK---IDDI-IDQEVQHLSGGEL 472
R + + L Q +++ + +D I +D++ Q LSGG
Sbjct: 140 ERFFVADNVLDEITFGWPRQKGSLQLKEQLTSNLQRAFNWVGLDSIPLDKDPQLLSGGYK 199
Query: 473 QRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATY 532
+R+A+ + L D+ ++DEP A LD + R +K+++ L + T +V HD
Sbjct: 200 RRLALAIQLVQTPDLLILDEPLAGLDWKARADVAKLLKH--LKKELTLLVVSHDLRELAA 257
Query: 533 LADK 536
L D+
Sbjct: 258 LVDQ 261
>At3g55090 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 720
Score = 55.1 bits (131), Expect = 3e-07
Identities = 53/206 (25%), Positives = 88/206 (41%), Gaps = 31/206 (15%)
Query: 371 AGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVR 430
+GE D +IL ++G +G+GK+TLI LA I + LN ++ + V
Sbjct: 96 SGETRDGEILAVLGASGSGKSTLIDALANRIAKGSLKGTVTLNGEALQSRMLKVISAYVM 155
Query: 431 Q--LFFKRIR--------AQFLNPQFQTDVVKPLKIDDIIDQ------------EVQH-- 466
Q L F + A+F P+ K L++ +IDQ + H
Sbjct: 156 QDDLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIRNAAKTIIGDEGHRG 215
Query: 467 LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHD 526
+SGGE +RV+I + + + + +DEP++ LDS + KV++R +
Sbjct: 216 ISGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTSAFMVVKVLKRIAESGSIIIMSIHQP 275
Query: 527 FIMATYLADKVI-------VFDGIPS 545
L D++I VF G P+
Sbjct: 276 SHRVLSLLDRLIFLSRGHTVFSGSPA 301
>At2g47000 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1286
Score = 54.7 bits (130), Expect = 4e-07
Identities = 50/198 (25%), Positives = 92/198 (46%), Gaps = 31/198 (15%)
Query: 352 AFTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ-D 408
+F YP Q D L++ AG+ + ++GE+G+GK+T+I LL D G+
Sbjct: 1048 SFKYPARPDVQIFQDLCLSIRAGK-----TVALVGESGSGKSTVIALLQRFYDPDSGEIT 1102
Query: 409 IPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRAQFL----NPQFQTDVVKPLKI----- 456
+ + + K + TG V Q LF + IRA ++++V ++
Sbjct: 1103 LDGVEIKSLRLKWLRQQTGLVSQEPILFNETIRANIAYGKGGDASESEIVSSAELSNAHG 1162
Query: 457 ---------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSK 507
D ++ + LSGG+ QRVAI ++ + + L+DE ++ LD+E +
Sbjct: 1163 FISGLQQGYDTMVGERGIQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQD 1222
Query: 508 VIRRFILHNKKTAFIVEH 525
+ R +++ +T +V H
Sbjct: 1223 ALDRVMVN--RTTIVVAH 1238
Score = 51.6 bits (122), Expect = 3e-06
Identities = 53/202 (26%), Positives = 94/202 (46%), Gaps = 28/202 (13%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G + LVG +G GKST + ++ RF DP +I G L+ + K +
Sbjct: 412 GTTVALVGQSGSGKSTVVSLIE--------RFYDPQAGDVLID---GINLKEFQLKWIRS 460
Query: 163 DIKAIIKPQYV------DNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQ--LKNV 214
I + + + DNI G E +K E + +A +++D L L +
Sbjct: 461 KIGLVSQEPVLFTASIKDNIAY---GKEDATTEEIKAAAELA--NASKFVDKLPQGLDTM 515
Query: 215 LNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTTY 273
+ + LSGG+ QR A+ + +++ + + DE +S LD + +R+ + R ++N TT
Sbjct: 516 VGEHGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTTV 575
Query: 274 VICVEHDLSVLDYLSDFVCIIY 295
V V H LS + +D + +I+
Sbjct: 576 V--VAHRLSTVRN-ADMIAVIH 594
Score = 51.2 bits (121), Expect = 4e-06
Identities = 56/219 (25%), Positives = 96/219 (43%), Gaps = 18/219 (8%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
R G+ + LVG +G GKST + +L RF DP + + G E+++ K L
Sbjct: 1068 RAGKTVALVGESGSGKSTVIALLQ--------RFYDPDSGEITLD---GVEIKSLRLKWL 1116
Query: 161 EDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKD--DAKRYIDILQ--LKNVLN 216
+ + + N K G+ + + S + +A +I LQ ++
Sbjct: 1117 RQQTGLVSQEPILFNETIRANIAYGKGGDASESEIVSSAELSNAHGFISGLQQGYDTMVG 1176
Query: 217 REVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTTYVI 275
LSGG+ QR AI + V++ V + DE +S LD + +R+ + R ++N TT I
Sbjct: 1177 ERGIQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRVMVNRTT--I 1234
Query: 276 CVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPSSVREGI 314
V H LS + + GV G ++++G+
Sbjct: 1235 VVAHRLSTIKNADVIAVVKNGVIVEKGKHDTLINIKDGV 1273
>7301180 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1239
Score = 54.7 bits (130), Expect = 4e-07
Identities = 75/302 (24%), Positives = 131/302 (42%), Gaps = 28/302 (9%)
Query: 255 KQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGVPSVYGVVTLPSSVREGI 314
+ L L +L+ T V S + L I Y + +G L S R
Sbjct: 245 RSTLYITLAAAALMGQTITADFVFSAASYYNILQLVAAIWYPLAVSFGAEALVSLRRIQD 304
Query: 315 NIFLDGHIPSENLRFRTEALQFRMADAGDELEA----DASRAFTYPDMKRTQGDFSLTVE 370
+ L+G RT+ L + G + A D + ++ ++T +L +E
Sbjct: 305 FLMLEGR------EERTQGLTHKRDQEGGDSRAVTIKDINASWDIEKPQKTLQSINLQIE 358
Query: 371 AGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVR 430
G Q+ ++G G GK+++++LL G +P DG + ++S Q+ FTG+VR
Sbjct: 359 KG-----QLCAVIGPVGAGKSSILQLLLGELPVIDGGVFIQGDLSYAAQE-PWLFTGSVR 412
Query: 431 Q--LF---FKRIRAQFLNP--QFQTDVVK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLG 482
LF F R R Q + TD + P ++ + LSGG+ R+++ ++
Sbjct: 413 NNILFGEEFDRKRYQEVTRCCALSTDFQQLPNGDKTLVGERGASLSGGQRARISLARAVY 472
Query: 483 MNADIYLIDEPSAYLDSE-QRIICSKVI--RRFILHNKKTAFIVEHDFIMATYLADKVIV 539
A IYL+D+P + +D+ R + +VI R + K T +V H + AD +++
Sbjct: 473 KPAQIYLMDDPLSAVDAHVGRHLFDEVIGPRGRLAQLKATRILVTHQVHFLSE-ADVIVI 531
Query: 540 FD 541
D
Sbjct: 532 VD 533
>At5g61700 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 888
Score = 54.3 bits (129), Expect = 5e-07
Identities = 53/186 (28%), Positives = 86/186 (45%), Gaps = 24/186 (12%)
Query: 375 SDSQILVMMGENGTGKTTLIKLLAGAIPADDG----------QDIPKLNVSMK--PQK-- 420
S + M+G NG GKT+ I ++ G + G +D+ K+ SM PQ
Sbjct: 595 SSGECFGMLGPNGAGKTSFISMMTGLLKPSSGTALVQGLDICKDMNKVYTSMGVCPQHDL 654
Query: 421 IAPKFTGTVRQLFF---KRIRAQFLNPQFQTDVVKPLKIDD--IIDQEVQHLSGGELQRV 475
+ TG LF+ K I+ L Q + +K + + D + D+ + SGG +R+
Sbjct: 655 LWETLTGREHLLFYGRLKNIKGSDLT-QAVEESLKSVSLYDGGVGDKPAGNYSGGMKRRL 713
Query: 476 AIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIV-EHDFIMATYLA 534
++ +SL N + +DEPS LD R VI+R + TA I+ H A +L
Sbjct: 714 SVAISLIGNPKVVYLDEPSTGLDPASRKNLWNVIKR---AKQNTAIILTTHSMEEAEFLC 770
Query: 535 DKVIVF 540
D++ +F
Sbjct: 771 DRLGIF 776
>At3g47750 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 895
Score = 54.3 bits (129), Expect = 5e-07
Identities = 55/201 (27%), Positives = 86/201 (42%), Gaps = 27/201 (13%)
Query: 359 KRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDG----------QD 408
K G S+ V GE M+G NG GKT+ I ++ G + G QD
Sbjct: 591 KMAVGGLSIAVPPGE-----CFGMLGPNGAGKTSFINMMTGLVKPTSGTALVESLDICQD 645
Query: 409 IPKLNVSMK--PQK--IAPKFTGTVRQLFF---KRIRAQFLNPQFQTDVVKP-LKIDDII 460
+ K+ SM PQ + TG LF+ K ++ LN + + L + +
Sbjct: 646 MDKVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNLKGSDLNQAIEESLKSVNLSREGVA 705
Query: 461 DQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTA 520
D+ SGG +R+++ +SL + + +DEPS LD R I+ K TA
Sbjct: 706 DKPAGKYSGGMKRRLSVAISLIGSPKVVYMDEPSTGLDPASRRSLWTAIKG---AKKHTA 762
Query: 521 FIV-EHDFIMATYLADKVIVF 540
I+ H A +L D++ +F
Sbjct: 763 IILTTHSMEEAEFLCDRLGIF 783
>At3g28390 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1225
Score = 53.9 bits (128), Expect = 7e-07
Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 33/196 (16%)
Query: 354 TYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAG------AIPADDGQ 407
T PD+ Q +FS+ +E G+ + ++G +G+GK+T+I L+ I DG+
Sbjct: 991 TRPDVIIFQ-NFSIDIEDGKST-----AIVGPSGSGKSTIISLIERFYDPLKGIVKIDGR 1044
Query: 408 DIPKLNVSMKPQKIA------PKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDII- 460
DI ++ Q IA F GT+R+ + ++ + K D I
Sbjct: 1045 DIRSCHLRSLRQHIALVSQEPTLFAGTIRENIMYGGASNKIDESEIIEAAKAANAHDFIT 1104
Query: 461 -----------DQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVI 509
D+ VQ LSGG+ QR+AI ++ N + L+DE ++ LDS+ + +
Sbjct: 1105 SLSNGYDTCCGDRGVQ-LSGGQKQRIAIARAVLKNPSVLLLDEATSALDSQSESVVQDAL 1163
Query: 510 RRFILHNKKTAFIVEH 525
R ++ +T+ ++ H
Sbjct: 1164 ERLMV--GRTSVVIAH 1177
>Hs9506365 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2146
Score = 53.5 bits (127), Expect = 9e-07
Identities = 41/187 (21%), Positives = 86/187 (45%), Gaps = 20/187 (10%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLLAGAIPADD------GQDIPKLNVSMKPQ-KIAPKF 425
+F I +G NG GKTT + +L+G P G D+ +++P + P++
Sbjct: 830 DFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQY 889
Query: 426 TGTVRQL-------FFKRIR---AQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRV 475
L F+ R++ A + P+ Q +++ + + + +HLSGG +++
Sbjct: 890 NVLFDMLTVDEHVWFYGRLKGLSAAVVGPE-QDRLLQDVGLVSKQSVQTRHLSGGMQRKL 948
Query: 476 AIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLAD 535
++ ++ + + ++DEP+A +D R +++ ++ +T + H A L D
Sbjct: 949 SVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY--REGRTLILSTHHLDEAELLGD 1006
Query: 536 KVIVFDG 542
+V V G
Sbjct: 1007 RVAVVAG 1013
>Hs16156905 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2273
Score = 53.5 bits (127), Expect = 9e-07
Identities = 40/185 (21%), Positives = 85/185 (45%), Gaps = 24/185 (12%)
Query: 374 FSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ------------DIPKLNVSMKPQK- 420
F ++QI +G NG GKTT + +L G +P G D + ++ M PQ
Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1012
Query: 421 -IAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDI-----IDQEVQHLSGGELQR 474
+ T LF+ +++ + Q + + ++D ++E Q LSGG ++
Sbjct: 1013 ILFHHLTVAEHMLFYAQLKGK---SQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRK 1069
Query: 475 VAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLA 534
+++ ++ +A + ++DEP++ +D R ++ ++ + +T + H A L
Sbjct: 1070 LSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLG 1127
Query: 535 DKVIV 539
D++ +
Sbjct: 1128 DRIAI 1132
>Hs15451838 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2008
Score = 53.5 bits (127), Expect = 9e-07
Identities = 41/187 (21%), Positives = 86/187 (45%), Gaps = 20/187 (10%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLLAGAIPADD------GQDIPKLNVSMKPQ-KIAPKF 425
+F I +G NG GKTT + +L+G P G D+ +++P + P++
Sbjct: 692 DFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQY 751
Query: 426 TGTVRQL-------FFKRIR---AQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRV 475
L F+ R++ A + P+ Q +++ + + + +HLSGG +++
Sbjct: 752 NVLFDMLTVDEHVWFYGRLKGLSAAVVGPE-QDRLLQDVGLVSKQSVQTRHLSGGMQRKL 810
Query: 476 AIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLAD 535
++ ++ + + ++DEP+A +D R +++ ++ +T + H A L D
Sbjct: 811 SVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY--REGRTLILSTHHLDEAELLGD 868
Query: 536 KVIVFDG 542
+V V G
Sbjct: 869 RVAVVAG 875
>CE23999 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1269
Score = 53.5 bits (127), Expect = 9e-07
Identities = 58/212 (27%), Positives = 91/212 (42%), Gaps = 40/212 (18%)
Query: 354 TYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DGQ 407
T PD + +G S V+ GE + ++G +G+GK+T+++LL D DG
Sbjct: 392 TRPDAQVLKG-ISFDVQNGE-----CIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGM 445
Query: 408 DIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRA--QFLNPQFQTDVVK---------- 452
D+ +N+ K + G V Q LF I +F NP +
Sbjct: 446 DLNDMNI-----KRLRRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPEIYGALRKANAYD 500
Query: 453 -----PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSK 507
P I I+ + LSGG+ QR+AI +L N I L+DE ++ LD+E + K
Sbjct: 501 FVCSFPKGIKTIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQK 560
Query: 508 VIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ +T +V H + A K+IV
Sbjct: 561 ALEN--ASQGRTTIVVAHR-LSTIRNASKIIV 589
>CE23998 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1225
Score = 53.5 bits (127), Expect = 9e-07
Identities = 58/212 (27%), Positives = 91/212 (42%), Gaps = 40/212 (18%)
Query: 354 TYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DGQ 407
T PD + +G S V+ GE + ++G +G+GK+T+++LL D DG
Sbjct: 354 TRPDAQVLKG-ISFDVQNGE-----CIALVGASGSGKSTVVQLLLHYYNIDSGNIFIDGM 407
Query: 408 DIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRA--QFLNPQFQTDVVK---------- 452
D+ +N+ K + G V Q LF I +F NP +
Sbjct: 408 DLNDMNI-----KRLRRVIGVVSQEPVLFNTTIEENIRFGNPNVSLPEIYGALRKANAYD 462
Query: 453 -----PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSK 507
P I I+ + LSGG+ QR+AI +L N I L+DE ++ LD+E + K
Sbjct: 463 FVCSFPKGIKTIVGERGTQLSGGQKQRIAIARTLVRNPKILLLDEATSALDNESEQVVQK 522
Query: 508 VIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ +T +V H + A K+IV
Sbjct: 523 ALEN--ASQGRTTIVVAHR-LSTIRNASKIIV 551
Score = 51.6 bits (122), Expect = 3e-06
Identities = 59/258 (22%), Positives = 102/258 (38%), Gaps = 61/258 (23%)
Query: 282 SVLDYLSDFVCIIYGVPSVYGV----VTLPSSVREGINIFLDGHIPSENLRFRTEALQFR 337
S YL D+ ++ ++ + T+P S +G G I EN++F + R
Sbjct: 934 SAAAYLPDYKKAVHAAGLIFHLFTYPATMPFSSSDGKKNIEKGEIIGENVQFHYDQRPDR 993
Query: 338 MADAGDELEADASRAFTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL 397
M G L+ D + L ++G +G GK+T+I LL
Sbjct: 994 MILNGVNLKVDPGKT---------------------------LALVGPSGCGKSTIISLL 1026
Query: 398 AGAIPADDGQ------DIPKLN----------VSMKP--------QKIAPKFTGTVRQLF 433
A DG+ ++ +N VS +P + + T +V QL
Sbjct: 1027 ERFYHAVDGEVKIDSENVEDINLNHLRSNLALVSQEPTLFNCSIRENLLYGLTRSVPQLE 1086
Query: 434 FKRI--RAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLID 491
++ A N FQ P +D ++ + LSGG+ QR+AI ++ N + L+D
Sbjct: 1087 LEKALQTANAFNFVFQF----PQGLDTLVGERGAQLSGGQKQRIAIARAILRNPKVLLLD 1142
Query: 492 EPSAYLDSEQRIICSKVI 509
E ++ LDS+ + +
Sbjct: 1143 EATSALDSDSEKVVQNAL 1160
>CE03262 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1327
Score = 53.5 bits (127), Expect = 9e-07
Identities = 46/155 (29%), Positives = 76/155 (48%), Gaps = 21/155 (13%)
Query: 378 QILVMMGENGTGKTTLIKLL------AGAIPADDGQDIPKLNVSMKPQKIA-----PK-F 425
Q + ++G +G+GK+T I +L G DGQDI KL++ ++A P+ F
Sbjct: 1115 QTVALVGPSGSGKSTNIGMLERFYDVTGGALRIDGQDIRKLSLFHLRTQMALVGQEPRLF 1174
Query: 426 TGTVRQ---LFFKRIRAQFLNPQFQTDVVK------PLKIDDIIDQEVQHLSGGELQRVA 476
GT+R+ L K + + +N + P ID + ++ LSGG+ QR+A
Sbjct: 1175 AGTIRENVCLGLKDVPLEKINQALELANANRFLANLPAGIDTDVGEKGGQLSGGQKQRIA 1234
Query: 477 IVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRR 511
I +L + I L+DE ++ LDSE + + R
Sbjct: 1235 IARALVRDPKILLLDEATSALDSESERAVQEALDR 1269
>At4g25450 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 280
Score = 53.5 bits (127), Expect = 9e-07
Identities = 53/188 (28%), Positives = 90/188 (47%), Gaps = 11/188 (5%)
Query: 99 TPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTK 158
T G V LVG++G GKST +++LA +P GR E ++ F SE +
Sbjct: 60 TLNSGTVTALVGSSGAGKSTIVQLLARFYEPTQGRI---TVGGEDVRMFDKSEWAKVVSI 116
Query: 159 MLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQ-LKNVLNR 217
+ ++ + + +NI + P + V + ++ K+ + I + Q ++
Sbjct: 117 VNQEPV--LFSLSVAENIAYGL--PNEHVSKDDIIKAAKAANAHDFIISLPQGYDTLVGE 172
Query: 218 EVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLD-VKQRLNAALIIRSLLNPTTYVIC 276
LSGG+ QR AI S ++ A + + DE +S LD V +RL + + R + + TT VI
Sbjct: 173 RGGLLSGGQRQRVAIARSLLKNAPILILDEATSALDAVSERLVQSALNRLMKDRTTLVIA 232
Query: 277 VEHDLSVL 284
H LS +
Sbjct: 233 --HRLSTV 238
>At3g55130 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 725
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/215 (24%), Positives = 90/215 (41%), Gaps = 35/215 (16%)
Query: 371 AGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLN---------------VS 415
+GE SD IL ++G +G GK+TLI LAG + + LN
Sbjct: 104 SGEASDGDILAVLGASGAGKSTLIDALAGRVAEGSLRGSVTLNGEKVLQSRLLKVISAYV 163
Query: 416 MKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQ------------E 463
M+ + P T +F ++F P+ + K +++ +IDQ +
Sbjct: 164 MQDDLLFPMLTVKETLMF----ASEFRLPRSLSKSKKMERVEALIDQLGLRNAANTVIGD 219
Query: 464 VQH--LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAF 521
H +SGGE +RV+I + + + + +DEP++ LDS + +V++R
Sbjct: 220 EGHRGVSGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTNAFMVVQVLKRIAQSGSIVIM 279
Query: 522 IVEHDFIMATYLADKVIVFDGIPSKQAFARAPESL 556
+ L D++I+ K F +P SL
Sbjct: 280 SIHQPSARIVELLDRLIILS--RGKSVFNGSPASL 312
>At3g55110 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 708
Score = 53.5 bits (127), Expect = 9e-07
Identities = 56/235 (23%), Positives = 94/235 (39%), Gaps = 35/235 (14%)
Query: 351 RAFTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIP 410
R F + K L GE D +IL ++G +G GK+TLI LAG + D +
Sbjct: 76 RRFDFSRRKTASVKTLLDDITGEARDGEILAVLGGSGAGKSTLIDALAGRVAEDSLKGTV 135
Query: 411 KLN---------------VSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLK 455
LN M+ + P T +F ++F P+ K +
Sbjct: 136 TLNGEKVLQSRLLKVISAYVMQDDLLFPMLTVKETLMF----ASEFRLPRSLPKSKKMER 191
Query: 456 IDDIIDQ------------EVQH--LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQ 501
++ +IDQ + H +SGGE +RV+I + + + + +DEP++ LDS
Sbjct: 192 VETLIDQLGLRNAADTVIGDEGHRGVSGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTN 251
Query: 502 RIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDGIPSKQAFARAPESL 556
+ +V++R + L D++I+ K F +P SL
Sbjct: 252 AFMVVQVLKRIAQSGSVVIMSIHQPSARIIGLLDRLIILS--HGKSVFNGSPVSL 304
>HsM4502457 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1321
Score = 53.1 bits (126), Expect = 1e-06
Identities = 50/171 (29%), Positives = 76/171 (44%), Gaps = 26/171 (15%)
Query: 353 FTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DG 406
FTYP +Q L+V S Q L +G +G GK+T I+LL D DG
Sbjct: 1085 FTYPSRPDSQVLNGLSVS---ISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDG 1141
Query: 407 QDIPKLNV----------SMKPQKIAP------KFTGTVRQLFFKRIRAQFLNPQFQTDV 450
D K+NV S +P A K+ +++ +R+ A Q V
Sbjct: 1142 HDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFV 1201
Query: 451 VK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE 500
+ P K + + + LS GE QR+AI ++ + I L+DE ++ LD+E
Sbjct: 1202 MSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTE 1252
Score = 50.4 bits (119), Expect = 8e-06
Identities = 55/232 (23%), Positives = 95/232 (40%), Gaps = 36/232 (15%)
Query: 76 PTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFE 135
P+ DSQV + S + PGQ L VG++G GKST++++L RF
Sbjct: 1088 PSRPDSQVLNGLSVSI---------SPGQTLAFVGSSGCGKSTSIQLLE--------RFY 1130
Query: 136 DPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKP------QYVDNIPRAIKGPVQKVGE 189
DP + + +I G + + + L +I + + +DNI E
Sbjct: 1131 DPDQGKVMID---GHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYG-----DNTKE 1182
Query: 190 LLKLRLEKSKDDAKRYIDILQLKNVLNREV----SALSGGELQRFAIGMSCVQEADVYMF 245
+ R+ + A+ + ++ L V S LS GE QR AI + V++ + +
Sbjct: 1183 IPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLL 1242
Query: 246 DEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGV 297
DE +S LD + + + T ++ + H LS + + GV
Sbjct: 1243 DEATSALDTESEKTVQVALDKAREGRTCIV-IAHRLSTIQNADIIAVMAQGV 1293
>Hs9961252 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1232
Score = 53.1 bits (126), Expect = 1e-06
Identities = 48/172 (27%), Positives = 82/172 (46%), Gaps = 30/172 (17%)
Query: 353 FTYP---DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD----- 404
F+YP ++K +G +L V++G Q + ++G +G GK+T ++L+ D
Sbjct: 401 FSYPSRANVKILKG-LNLKVQSG-----QTVALVGSSGCGKSTTVQLIQRLYDPDEGTIN 454
Query: 405 -DGQDIPKLNVSMKPQKIAPK------FTGTVRQ--------LFFKRIRAQFLNPQFQTD 449
DGQDI NV+ + I F+ T+ + + I+
Sbjct: 455 IDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEF 514
Query: 450 VVK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE 500
++K P K D ++ + LSGG+ QR+AI +L N I L+DE ++ LD+E
Sbjct: 515 IMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTE 566
Score = 50.8 bits (120), Expect = 6e-06
Identities = 51/195 (26%), Positives = 87/195 (44%), Gaps = 34/195 (17%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLL-------AGAIPADDGQDIPKLNV----------S 415
E Q L ++G +G GK+T+++LL AG + D GQ+ KLNV S
Sbjct: 1011 EVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLD-GQEAKKLNVQWLRAQLGIVS 1069
Query: 416 MKP--------QKIAPKFTGTV--RQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQ 465
+P + IA V + +A ++P +T P K + + +
Sbjct: 1070 QEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIET---LPHKYETRVGDKGT 1126
Query: 466 HLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEH 525
LSGG+ QR+AI +L I L+DE ++ LD+E + + + + +T ++ H
Sbjct: 1127 QLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAH 1184
Query: 526 DFIMATYLADKVIVF 540
+ AD ++VF
Sbjct: 1185 R-LSTIQNADLIVVF 1198
>Hs9961250 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1286
Score = 53.1 bits (126), Expect = 1e-06
Identities = 48/172 (27%), Positives = 82/172 (46%), Gaps = 30/172 (17%)
Query: 353 FTYP---DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD----- 404
F+YP ++K +G +L V++G Q + ++G +G GK+T ++L+ D
Sbjct: 401 FSYPSRANVKILKG-LNLKVQSG-----QTVALVGSSGCGKSTTVQLIQRLYDPDEGTIN 454
Query: 405 -DGQDIPKLNVSMKPQKIAPK------FTGTVRQ--------LFFKRIRAQFLNPQFQTD 449
DGQDI NV+ + I F+ T+ + + I+
Sbjct: 455 IDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEF 514
Query: 450 VVK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE 500
++K P K D ++ + LSGG+ QR+AI +L N I L+DE ++ LD+E
Sbjct: 515 IMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTE 566
Score = 51.2 bits (121), Expect = 4e-06
Identities = 52/201 (25%), Positives = 88/201 (42%), Gaps = 39/201 (19%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLL-------AGAIPAD------DGQDIPKLNV----- 414
E Q L ++G +G GK+T+++LL AG + D DGQ+ KLNV
Sbjct: 1058 EVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVFVDFGFQLLDGQEAKKLNVQWLRA 1117
Query: 415 -----SMKP--------QKIAPKFTGTV--RQLFFKRIRAQFLNPQFQTDVVKPLKIDDI 459
S +P + IA V + +A ++P +T P K +
Sbjct: 1118 QLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIET---LPHKYETR 1174
Query: 460 IDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKT 519
+ + LSGG+ QR+AI +L I L+DE ++ LD+E + + + + +T
Sbjct: 1175 VGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK--AREGRT 1232
Query: 520 AFIVEHDFIMATYLADKVIVF 540
++ H + AD ++VF
Sbjct: 1233 CIVIAHR-LSTIQNADLIVVF 1252
>Hs6995996 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1480
Score = 53.1 bits (126), Expect = 1e-06
Identities = 50/191 (26%), Positives = 92/191 (47%), Gaps = 26/191 (13%)
Query: 364 DFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAP 423
D + +E G Q+L + G G GKT+L+ ++ G + +G+ +S Q +
Sbjct: 443 DINFKIERG-----QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSGRISFCSQ-FSW 496
Query: 424 KFTGTVRQLFF-------KRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQ-HLSGGELQRV 475
GT+++ R R+ Q + D+ K + D+I+ E LSGG+ R+
Sbjct: 497 IMPGTIKENIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARI 556
Query: 476 AIVLSLGMNADIYLIDEPSAYLD--SEQRIICSKVIRRFILHNKKTAFI---VEHDFIMA 530
++ ++ +AD+YL+D P YLD +E+ I S V + ++ NK + +EH
Sbjct: 557 SLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCK--LMANKTRILVTSKMEH----- 609
Query: 531 TYLADKVIVFD 541
ADK+++ +
Sbjct: 610 LKKADKILILN 620
>Hs4505771 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1279
Score = 53.1 bits (126), Expect = 1e-06
Identities = 48/172 (27%), Positives = 82/172 (46%), Gaps = 30/172 (17%)
Query: 353 FTYP---DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD----- 404
F+YP ++K +G +L V++G Q + ++G +G GK+T ++L+ D
Sbjct: 401 FSYPSRANVKILKG-LNLKVQSG-----QTVALVGSSGCGKSTTVQLIQRLYDPDEGTIN 454
Query: 405 -DGQDIPKLNVSMKPQKIAPK------FTGTVRQ--------LFFKRIRAQFLNPQFQTD 449
DGQDI NV+ + I F+ T+ + + I+
Sbjct: 455 IDGQDIRNFNVNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEF 514
Query: 450 VVK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE 500
++K P K D ++ + LSGG+ QR+AI +L N I L+DE ++ LD+E
Sbjct: 515 IMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTE 566
Score = 50.8 bits (120), Expect = 6e-06
Identities = 51/195 (26%), Positives = 87/195 (44%), Gaps = 34/195 (17%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLL-------AGAIPADDGQDIPKLNV----------S 415
E Q L ++G +G GK+T+++LL AG + D GQ+ KLNV S
Sbjct: 1058 EVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLD-GQEAKKLNVQWLRAQLGIVS 1116
Query: 416 MKP--------QKIAPKFTGTV--RQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQ 465
+P + IA V + +A ++P +T P K + + +
Sbjct: 1117 QEPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHPFIET---LPHKYETRVGDKGT 1173
Query: 466 HLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEH 525
LSGG+ QR+AI +L I L+DE ++ LD+E + + + + +T ++ H
Sbjct: 1174 QLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAH 1231
Query: 526 DFIMATYLADKVIVF 540
+ AD ++VF
Sbjct: 1232 R-LSTIQNADLIVVF 1245
>Hs21536378 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1321
Score = 53.1 bits (126), Expect = 1e-06
Identities = 50/171 (29%), Positives = 76/171 (44%), Gaps = 26/171 (15%)
Query: 353 FTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DG 406
FTYP +Q L+V S Q L +G +G GK+T I+LL D DG
Sbjct: 1085 FTYPSRPDSQVLNGLSVS---ISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDG 1141
Query: 407 QDIPKLNV----------SMKPQKIAP------KFTGTVRQLFFKRIRAQFLNPQFQTDV 450
D K+NV S +P A K+ +++ +R+ A Q V
Sbjct: 1142 HDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFV 1201
Query: 451 VK-PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE 500
+ P K + + + LS GE QR+AI ++ + I L+DE ++ LD+E
Sbjct: 1202 MSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTE 1252
Score = 50.4 bits (119), Expect = 8e-06
Identities = 55/232 (23%), Positives = 95/232 (40%), Gaps = 36/232 (15%)
Query: 76 PTNLDSQVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFE 135
P+ DSQV + S + PGQ L VG++G GKST++++L RF
Sbjct: 1088 PSRPDSQVLNGLSVSI---------SPGQTLAFVGSSGCGKSTSIQLLE--------RFY 1130
Query: 136 DPPEWQEIIKYFRGSELQNYFTKMLEDDIKAIIKP------QYVDNIPRAIKGPVQKVGE 189
DP + + +I G + + + L +I + + +DNI E
Sbjct: 1131 DPDQGKVMID---GHDSKKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYG-----DNTKE 1182
Query: 190 LLKLRLEKSKDDAKRYIDILQLKNVLNREV----SALSGGELQRFAIGMSCVQEADVYMF 245
+ R+ + A+ + ++ L V S LS GE QR AI + V++ + +
Sbjct: 1183 IPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLL 1242
Query: 246 DEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSDFVCIIYGV 297
DE +S LD + + + T ++ + H LS + + GV
Sbjct: 1243 DEATSALDTESEKTVQVALDKAREGRTCIV-IAHRLSTIQNADIIAVMAQGV 1293
>At5g46540 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1248
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/202 (25%), Positives = 96/202 (46%), Gaps = 30/202 (14%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G + LVG +G GKST + ++ RF DP + +I G +L+ + K +
Sbjct: 385 GMTVALVGQSGSGKSTVISLIE--------RFYDPESGEVLID---GIDLKKFQVKWIRS 433
Query: 163 DIKAIIKPQYV------DNIPRAIKGPV-QKVGELLKLRLEKSKDDAKRYIDILQ--LKN 213
I + + + +NI K Q++ LKL +A +ID L L+
Sbjct: 434 KIGLVSQEPILFATTIRENIVYGKKDASDQEIRTALKLA------NASNFIDKLPQGLET 487
Query: 214 VLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVK-QRLNAALIIRSLLNPTT 272
++ + LSGG+ QR AI + ++ + + DE +S LD + +R+ +++ +L+ TT
Sbjct: 488 MVGEHGTQLSGGQKQRIAIARAILKNPKILLLDEATSALDAESERIVQDALVKLMLSRTT 547
Query: 273 YVICVEHDLSVLDYLSDFVCII 294
V V H L+ + +D + ++
Sbjct: 548 VV--VAHRLTTI-RTADMIAVV 566
Score = 52.4 bits (124), Expect = 2e-06
Identities = 51/191 (26%), Positives = 86/191 (44%), Gaps = 29/191 (15%)
Query: 356 PDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DGQDI 409
PD++ G FSLTV G + ++G++G+GK+T+I L+ + DG D+
Sbjct: 370 PDVQIFVG-FSLTVPNG-----MTVALVGQSGSGKSTVISLIERFYDPESGEVLIDGIDL 423
Query: 410 PKLNVSMKPQKIAPK------FTGTVRQLFF--------KRIRAQFLNPQFQTDVVK-PL 454
K V KI F T+R+ + IR + K P
Sbjct: 424 KKFQVKWIRSKIGLVSQEPILFATTIRENIVYGKKDASDQEIRTALKLANASNFIDKLPQ 483
Query: 455 KIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFIL 514
++ ++ + LSGG+ QR+AI ++ N I L+DE ++ LD+E I + + +L
Sbjct: 484 GLETMVGEHGTQLSGGQKQRIAIARAILKNPKILLLDEATSALDAESERIVQDALVKLML 543
Query: 515 HNKKTAFIVEH 525
+T +V H
Sbjct: 544 --SRTTVVVAH 552
>At1g67940 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 263
Score = 53.1 bits (126), Expect = 1e-06
Identities = 49/196 (25%), Positives = 88/196 (44%), Gaps = 21/196 (10%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G ++G++G +G GKST L+ +L R +PPE + G ++ N L
Sbjct: 55 GMIVGVIGPSGSGKSTFLR--------SLNRLWEPPE---STVFLDGEDITNVDVIALRR 103
Query: 163 DIKAIIKPQYVDNIPRAIKGPV-QKVGELLKLRLEK-SKDDAKRYIDILQLKNVLNREVS 220
+ + + +P +G V V LR EK S ++ + + + L ++
Sbjct: 104 RVGMLFQ------LPVLFQGTVADNVRYGPNLRGEKLSDEEVYKLLSLADLDASFAKKTG 157
Query: 221 A-LSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAA-LIIRSLLNPTTYVICVE 278
A LS G+ QR A+ + E +V + DEP+S LD N +I++ + V
Sbjct: 158 AELSVGQAQRVALARTLANEPEVLLLDEPTSALDPISTENIEDVIVKLKKQRGITTVIVS 217
Query: 279 HDLSVLDYLSDFVCII 294
H + + ++D VC++
Sbjct: 218 HSIKQIQKVADIVCLV 233
>7301757 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1346
Score = 53.1 bits (126), Expect = 1e-06
Identities = 43/179 (24%), Positives = 80/179 (44%), Gaps = 24/179 (13%)
Query: 373 EFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVRQL 432
+ D + ++G G GK++ + +L G + D G+ + +S Q+ + F GT+R
Sbjct: 446 DIKDQTLAAVVGPVGAGKSSFLNVLLGEVGIDKGEAMVHGKISYASQE-SWVFEGTIRDN 504
Query: 433 FFKRIRAQFLNPQFQTDVVKPLKID-----------DIIDQEVQHLSGGELQRVAIVLSL 481
+ + N + VVK ++ ++ + LSGG+ RV++ ++
Sbjct: 505 I---VFVEDYNERRYKKVVKVCGLERDMELLPRGDLTVVGERGVSLSGGQKARVSLARAV 561
Query: 482 GMNADIYLIDEPSAYLDSEQ---------RIICSKVIRRFILHNKKTAFIVEHDFIMAT 531
ADIYL+D+P + +D+ R S IR + H + F VEH +M +
Sbjct: 562 YRKADIYLLDDPLSAVDTHVGKHIFDRCIRDFLSNKIRILVTHQVQYLFDVEHLLLMGS 620
>7298517 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1275
Score = 53.1 bits (126), Expect = 1e-06
Identities = 50/193 (25%), Positives = 94/193 (47%), Gaps = 24/193 (12%)
Query: 361 TQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQK 420
T +L V AG ++ ++G G+GK++LI+ + G + + G+ ++S Q+
Sbjct: 417 TLSGVNLQVHAGA-----LVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQE 471
Query: 421 IAPKFTGTVRQ-LFFKR----------IRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSG 469
F+GTVRQ + F + +R L F+ + PLK I+ LSG
Sbjct: 472 -PWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFE---LLPLKDKTILGDRGASLSG 527
Query: 470 GELQRVAIVLSLGMNADIYLIDEPSAYLDSE-QRIICSKVIRRFILHNKKTAFIVEHDFI 528
G+ R+++ S+ +A IYL+D+P + +DS R + + +R + K +V H +
Sbjct: 528 GQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHL--RDKIVILVTHQ-L 584
Query: 529 MATYLADKVIVFD 541
AD++++ +
Sbjct: 585 QFLQQADQIVIME 597
>Hs22057784 [U] KOG0058 Peptide exporter ABC superfamily
Length = 359
Score = 52.8 bits (125), Expect = 2e-06
Identities = 44/156 (28%), Positives = 74/156 (47%), Gaps = 19/156 (12%)
Query: 376 DSQILVMMGENGTGKTTLIKLL------AGAIPADDGQDIPKLNVSMKPQKIAPKFTGTV 429
+ + ++G G+GK+T++ LL A + DG DI +LN KI GT
Sbjct: 169 ERSVTALVGPGGSGKSTVLSLLLRLFDPASGTISLDGHDIRQLNPVWLRSKI-----GTQ 223
Query: 430 RQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYL 489
Q + A L F P + ++ ++ LSGG+ QR+AI +L N I L
Sbjct: 224 VQRVAEVANAVVLIRNF------PQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILL 277
Query: 490 IDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEH 525
+DE ++ LD+E + + + L + +TA ++ H
Sbjct: 278 LDEATSALDAENEYLVQEALDP--LMDGRTALVIAH 311
>At2g39480 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1407
Score = 52.8 bits (125), Expect = 2e-06
Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 32/214 (14%)
Query: 353 FTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL-------AGAIPA 403
F YP +FSL V G Q + ++G +G+GK+T+I L+ AG +
Sbjct: 1165 FCYPTRPEVLVLSNFSLKVNGG-----QTVAVVGVSGSGKSTIISLIERYYDPVAGQVLL 1219
Query: 404 DDGQDIPKLNVSMKP------QKIAPKFTGTVRQ-LFFKRIRAQFLNPQFQTDVVK---- 452
D G+D+ N+ Q+ F+ T+R+ + + R A + +
Sbjct: 1220 D-GRDLKSYNLRWLRSHMGLIQQEPIIFSTTIRENIIYARHNASEAEMKEAARIANAHHF 1278
Query: 453 ----PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKV 508
P D I L+ G+ QR+AI + NA I LIDE S+ ++SE + +
Sbjct: 1279 ISSLPHGYDTHIGMRGVELTQGQKQRIAIARVVLKNAPILLIDEASSSIESESSRVVQEA 1338
Query: 509 IRRFILHNKKTAFIVEHDFIMATYLADKVIVFDG 542
+ I+ N KT ++ H M ++ D ++V +G
Sbjct: 1339 LDTLIMGN-KTTILIAHRVAMMRHV-DNIVVLNG 1370
>Hs4557876 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2273
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/185 (21%), Positives = 85/185 (45%), Gaps = 24/185 (12%)
Query: 374 FSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ------------DIPKLNVSMKPQK- 420
F ++QI +G NG GKTT + +L G +P G D + ++ M PQ
Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1012
Query: 421 -IAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDI-----IDQEVQHLSGGELQR 474
+ T LF+ +++ + Q + + ++D ++E Q LSGG ++
Sbjct: 1013 ILFHHLTVAEHMLFYAQLKGK---SQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRK 1069
Query: 475 VAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLA 534
+++ ++ +A + ++DEP++ +D R ++ ++ + +T + H A +
Sbjct: 1070 LSVAIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMPTHHMDEADHQG 1127
Query: 535 DKVIV 539
D++ +
Sbjct: 1128 DRIAI 1132
>CE03308 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1266
Score = 52.4 bits (124), Expect = 2e-06
Identities = 59/213 (27%), Positives = 92/213 (42%), Gaps = 37/213 (17%)
Query: 353 FTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL-------AGAIPA 403
F YP+ R +F+++ + GE + ++G +G GK+T I+L+ GA+
Sbjct: 1034 FAYPNRNRQLILNNFNMSAQFGE-----TVALVGPSGCGKSTSIQLIERYYDAICGAVKI 1088
Query: 404 DDGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQF---LNPQFQTDVVK-------- 452
DD DI ++V IA G LF IR L Q V K
Sbjct: 1089 DD-HDIRDISVKHLRHNIA--LVGQEPTLFNLTIRENITYGLENVSQEQVEKAATLANIH 1145
Query: 453 ------PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICS 506
P D + LSGG+ QR+AI ++ N I L+DE ++ LD+E I
Sbjct: 1146 SFVENLPEGYDTSVGASGGRLSGGQKQRIAIARAIVRNPKILLLDEATSALDTESEKIVQ 1205
Query: 507 KVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ + + L +T ++ H + ADK+IV
Sbjct: 1206 EALDKARL--GRTCVVIAHR-LSTIQNADKIIV 1235
>At5g06530 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 567
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/156 (28%), Positives = 73/156 (45%), Gaps = 23/156 (14%)
Query: 367 LTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDG------QDIP-------KLN 413
LT +G + ++L +MG +G+GKTTL+ LLAG I D P K+
Sbjct: 56 LTGISGSVNPGEVLALMGPSGSGKTTLLSLLAGRISQSSTGGSVTYNDKPYSKYLKSKIG 115
Query: 414 VSMKPQKIAPKFTGTVRQLFFKRIR-----AQFLNPQFQTDVVKPLKIDDIIDQE----- 463
+ + P T + R+R + Q DV++ L ++ D
Sbjct: 116 FVTQDDVLFPHLTVKETLTYAARLRLPKTLTREQKKQRALDVIQELGLERCQDTMIGGAF 175
Query: 464 VQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDS 499
V+ +SGGE +RV+I + +N + L+DEP++ LDS
Sbjct: 176 VRGVSGGERKRVSIGNEIIINPSLLLLDEPTSGLDS 211
>7303379 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1279
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/284 (25%), Positives = 121/284 (41%), Gaps = 65/284 (22%)
Query: 320 GHIPSENLRFRTEALQFRMADAGDELEADASRAFTYPDMKRTQGDFSLTVEAGEFSDSQI 379
GHI E +RFR A PD++ +G LTV+ Q
Sbjct: 400 GHIRFEGIRFRYPAR---------------------PDVEILKG---LTVDV---LPGQT 432
Query: 380 LVMMGENGTGKTTLIKLL-------AGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVRQL 432
+ +G +G GK+TLI+L+ AG++ D G+D+ LNV +I G L
Sbjct: 433 VAFVGASGCGKSTLIQLMQRFYDPEAGSVKLD-GRDLRTLNVGWLRSQIG--VVGQEPVL 489
Query: 433 FFKRI--RAQFLNPQF-QTDVVK--------------PLKIDDIIDQEVQHLSGGELQRV 475
F I ++ P Q D+ K P D + ++ +SGG+ QR+
Sbjct: 490 FATTIGENIRYGRPSATQADIEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRI 549
Query: 476 AIVLSLGMNADIYLIDEPSAYLD--SEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYL 533
AI +L + L+DE ++ LD SE+R+ + + T +V H T
Sbjct: 550 AIARALVRQPQVLLLDEATSALDPTSEKRVQSALE----LASQGPTTLVVAHRLSTITN- 604
Query: 534 ADKVIVF-DGIPSKQAFARAPESLLTGCNKFLKNLNVTFRRDPT 576
ADK++ DG+ ++Q E L+ + + +++T R++ T
Sbjct: 605 ADKIVFLKDGVVAEQG---THEELMERRGLYCELVSITQRKEAT 645
>7294698 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 597
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/151 (25%), Positives = 76/151 (50%), Gaps = 16/151 (10%)
Query: 371 AGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMK-------PQKIAP 423
+G F + Q+ +MG +G GK++L+ ++G +D N+ MK Q
Sbjct: 18 SGSFRNGQLSAIMGPSGAGKSSLLNAISGF-----RRDGVTGNIKMKRDNACYITQDDHH 72
Query: 424 KFTGTVRQLFFK----RIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVL 479
+ TV +L +++ + + TD+++ L ++ + + LSGGE +R++I L
Sbjct: 73 QTLLTVEELMNLACDLKLKNRHKKAEIMTDILENLHLNHRRNVTAEKLSGGERKRLSIAL 132
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIR 510
L N +I+ +DEP++ LD C ++++
Sbjct: 133 ELVDNPNIFFLDEPTSGLDEVTAAQCIRLLQ 163
>YKL209c [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1290
Score = 52.0 bits (123), Expect = 3e-06
Identities = 42/155 (27%), Positives = 76/155 (48%), Gaps = 22/155 (14%)
Query: 378 QILVMMGENGTGKTTLIKLLAGAIPAD------DGQDIPKLNVSMKPQKIAPK------F 425
Q L ++GE+GTGK+TL+ LL + DG D+ N++ ++I+ F
Sbjct: 1081 QTLGIIGESGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLF 1140
Query: 426 TGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDIIDQEVQHL---------SGGELQRVA 476
GT+R ++ + L + D +K + I D + Q L SGG+ QR+
Sbjct: 1141 NGTIRDNLTYGLQDEILEIEMY-DALKYVGIHDFVISSPQGLDTRIDTTLLSGGQAQRLC 1199
Query: 477 IVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRR 511
I +L + I ++DE ++ LDS I ++++++
Sbjct: 1200 IARALLRKSKILILDECTSALDSVSSSIINEIVKK 1234
>SPCC663.03 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1362
Score = 52.0 bits (123), Expect = 3e-06
Identities = 69/327 (21%), Positives = 134/327 (40%), Gaps = 64/327 (19%)
Query: 259 NAALIIRSLLNPTTY----VICVEHDLSVLDYLSDFVCIIYGVPSV-----YGVVTLPSS 309
+AA + L+N T+ + + + +++ + + F+ I++G+ Y +
Sbjct: 1026 SAAQGVTFLINALTFWYGSTLMRKGEYNIVQFYTCFIAIVFGIQQAGQFFGYSADVTKAK 1085
Query: 310 VREGINIFLDGHIPSENL---------RFRTEALQFRMADAGDELEADASRAFTYPDMKR 360
G +L P + ++ A++FR + F+YP +
Sbjct: 1086 AAAGEIKYLSESKPKIDTWSTEGKKVESLQSAAIEFRQVE------------FSYPTRRH 1133
Query: 361 TQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD------DGQDIPKL 412
+ +LTV+ G+F + +G +G GK+T I L+ D DG ++
Sbjct: 1134 IKVLRGLNLTVKPGQF-----VAFVGSSGCGKSTTIGLIERFYDCDNGAVLVDGVNVRDY 1188
Query: 413 NVSMKPQKIA------PKFTGTVRQLFFKRIRAQFLNPQFQTDVVKPLKIDDII------ 460
N++ ++IA + GTVR+ ++ ++ + + K I + I
Sbjct: 1189 NINDYRKQIALVSQEPTLYQGTVRENIVLGA-SKDVSEEEMIEACKKANIHEFILGLPNG 1247
Query: 461 -----DQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILH 515
Q+ LSGG+ QR+AI +L N I L+DE ++ LDS + + +
Sbjct: 1248 YNTLCGQKGSSLSGGQKQRIAIARALIRNPKILLLDEATSALDSHSEKVVQEALN--AAS 1305
Query: 516 NKKTAFIVEHDFIMATYLADKVIVFDG 542
+T + H + + AD + VFDG
Sbjct: 1306 QGRTTVAIAHR-LSSIQDADCIFVFDG 1331
Score = 50.1 bits (118), Expect = 1e-05
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 32/210 (15%)
Query: 103 GQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLED 162
G++ LVG +G GKST + ++ RF DP Q + G +L+ L +
Sbjct: 448 GKITALVGASGSGKSTIIGLVE--------RFYDPIGGQVFLD---GKDLRTLNVASLRN 496
Query: 163 DIKAIIKPQYV------DNI----PRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLK 212
I + + + +NI P IKG + K E L+ R+ + A Y I+ L
Sbjct: 497 QISLVQQEPVLFATTVFENITYGLPDTIKGTLSK--EELERRVYDAAKLANAYDFIMTLP 554
Query: 213 NVLNREVSA----LSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLL 268
+ V +SGG+ QR AI + + + + + DE +S LD K + L+ ++L
Sbjct: 555 EQFSTNVGQRGFLMSGGQKQRIAIARAVISDPKILLLDEATSALDSKSEV---LVQKALD 611
Query: 269 NP--TTYVICVEHDLSVLDYLSDFVCIIYG 296
N + I + H LS + + V + G
Sbjct: 612 NASRSRTTIVIAHRLSTIRNADNIVVVNAG 641
>At3g47780 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 900
Score = 52.0 bits (123), Expect = 3e-06
Identities = 55/195 (28%), Positives = 88/195 (44%), Gaps = 29/195 (14%)
Query: 366 SLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDG----------QDIPKLNVS 415
SL V +GE M+G NG GKT+ I ++ G + G D+ ++ S
Sbjct: 603 SLAVPSGE-----CFGMLGPNGAGKTSFINMMTGLLKPTSGTALVQGLDICNDMDRVYTS 657
Query: 416 MK--PQK--IAPKFTGTVRQLFF---KRIRAQFLNPQFQTDVVKPLKI--DDIIDQEVQH 466
M PQ + TG LF+ K ++ LN Q + +K + + + D+
Sbjct: 658 MGVCPQHDLLWETLTGREHLLFYGRLKNLKGADLN-QAVEESLKSVNLFHGGVADKPAGK 716
Query: 467 LSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIV-EH 525
SGG +R+++ +SL N + +DEPS LD R VI+R + TA I+ H
Sbjct: 717 YSGGMKRRLSVAISLIGNPKVVYMDEPSTGLDPASRKNLWTVIKR---AKQNTAIILTTH 773
Query: 526 DFIMATYLADKVIVF 540
A +L D++ +F
Sbjct: 774 SMEEAEFLCDRLGIF 788
>CE06485 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1238
Score = 51.6 bits (122), Expect = 3e-06
Identities = 61/256 (23%), Positives = 100/256 (38%), Gaps = 57/256 (22%)
Query: 282 SVLDYLSDFVCIIYGVPSVYGVVTLPSSVR----EGINIFLDGHIPSENLRFRTEALQFR 337
S + Y+ DF I+ ++ + T P+++ G G + EN++F
Sbjct: 953 SAISYMPDFRKAIHSAGLIFNLFTYPATMPFNSDTGSRSITKGEVNGENVKFHYHQR--- 1009
Query: 338 MADAGDELEADASRAFTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL 397
PD +L VEAG+ L ++G +G+GK+T+I LL
Sbjct: 1010 ------------------PDYT-VLDSVNLKVEAGK-----TLAIVGPSGSGKSTIISLL 1045
Query: 398 AGAIPADDG------QDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFL----NPQFQ 447
AD G ++ +N+ + G V LF IR L Q
Sbjct: 1046 EMFYRADQGFIKIDNDNVENINLDHLRSNLGLVSQGPV--LFNCSIRDNILYGLTRNISQ 1103
Query: 448 TDVVKPLKI--------------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEP 493
T++ L+I D I+ LSGG+ QR+AI ++ N + L+DE
Sbjct: 1104 TEIENALQIANAFNFVFQLPQGLDTIVGDRGAQLSGGQKQRIAITRAILRNPKLLLLDEA 1163
Query: 494 SAYLDSEQRIICSKVI 509
++ LD+E I +
Sbjct: 1164 TSALDTESEKIVQNAL 1179
>At5g61740 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 848
Score = 51.6 bits (122), Expect = 3e-06
Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 22/178 (12%)
Query: 382 MMGENGTGKTTLIKLLAGAIPADDG----------QDIPKLNVSMK--PQK--IAPKFTG 427
M+G NG GKT+ I ++ G + G +D+ K+ SM PQ + TG
Sbjct: 562 MLGPNGAGKTSFINMMTGLLKPTSGTALVQGLDICKDMNKVYTSMGVCPQHDLLWGTLTG 621
Query: 428 TVRQLFFKRIRAQFLNPQFQT--DVVKPLKIDD--IIDQEVQHLSGGELQRVAIVLSLGM 483
LF+ R++ + Q + +K + + D + D+ SGG +R+++ +SL
Sbjct: 622 REHLLFYGRLKNIKGSALMQAVEESLKSVSLFDGGVADKPAGKYSGGMKRRLSVAISLIG 681
Query: 484 NADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIV-EHDFIMATYLADKVIVF 540
N + +DEPS LD R VI+R + TA I+ H A +L D++ +F
Sbjct: 682 NPKVVYMDEPSTGLDPASRKDLWTVIQR---AKQNTAIILTTHSMEEAEFLCDRLGIF 736
>At4g33460 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 270
Score = 51.6 bits (122), Expect = 3e-06
Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 29/166 (17%)
Query: 96 RLPTPRPGQVLGLVGTNGIGKSTALKILAGKQKPNLGR-FEDPPEWQEIIKYFRGSELQN 154
R+P+ GQ+ ++G NG GKST LKILAG P+ G F + P + QN
Sbjct: 66 RIPS---GQLWMILGPNGCGKSTLLKILAGVVNPSSGTVFVEKP---------KNFVFQN 113
Query: 155 YFTKMLEDDIKAIIK---PQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQL 211
+++ ++A + +Y D +K V K E + +R Y+ L L
Sbjct: 114 PDHQVVMPTVEADVAFGLGKYHDMNQEEVKSRVIKALEAVGMR---------DYMQFLLL 164
Query: 212 KN----VLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLD 253
K R + LSGG+ QR AI + + V + DE +++LD
Sbjct: 165 KYRFWCCFQRPIQTLSGGQKQRIAIAGALAEACKVLLLDELTTFLD 210
>At1g70610 [U] KOG0058 Peptide exporter ABC superfamily
Length = 659
Score = 51.6 bits (122), Expect = 3e-06
Identities = 55/208 (26%), Positives = 89/208 (42%), Gaps = 32/208 (15%)
Query: 102 PGQVLGLVGTNGIGKSTALKILAGKQKPNLGRF--EDPPEWQEIIKYFR------GSELQ 153
PG+V+ +VG +G GKST + +L +P G+ + P + +K+ R G E
Sbjct: 441 PGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILLDGVPLKELDVKWLRQRIGYVGQE-- 498
Query: 154 NYFTKMLEDDIKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKN 213
K+ DI + IK NI + + + A + I L N
Sbjct: 499 ---PKLFRTDISSNIKYGCDRNISQE--------------DIISAAKQAYAHDFITALPN 541
Query: 214 VLNREVS--ALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPT 271
N V LSGG+ QR AI + +++ + + DE +S LD + N ++RS+ N +
Sbjct: 542 GYNTIVDDDLLSGGQKQRIAIARAILRDPRILILDEATSALDAESEHNVKGVLRSIGNDS 601
Query: 272 T---YVICVEHDLSVLDYLSDFVCIIYG 296
VI + H LS + V + G
Sbjct: 602 ATKRSVIVIAHRLSTIQAADRIVAMDSG 629
>7291275 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1283
Score = 51.6 bits (122), Expect = 3e-06
Identities = 56/221 (25%), Positives = 102/221 (45%), Gaps = 24/221 (10%)
Query: 331 TEALQFRMADAGDELEADASRAFTYPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGK 390
T+ L FR A + + P +G S + AG+F + ++G G+GK
Sbjct: 396 TKCLSFRKVSASWD-----KPSIKQPRKPHIEG-ISFHINAGQF-----VGIVGNVGSGK 444
Query: 391 TTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVRQ--LFF-----KRIRAQFLN 443
+TL+ + G I G+ +S Q+ F G++R+ LF KR RA
Sbjct: 445 STLLHAILGEIELMQGRVEVHGRISYAAQQ-PWVFQGSIRENILFVEQYEEKRYRAVVHA 503
Query: 444 PQFQTDV-VKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSE-Q 501
Q D+ + P ++ + LSGG+ R+A+ ++ ADIYL D+P A +D++
Sbjct: 504 CQLDRDLELLPRGDATVVGERGISLSGGQKARIALARAVYRQADIYLFDDPLAAVDAQVG 563
Query: 502 RIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFDG 542
+++ K R +L K + H ++ + D++++ +G
Sbjct: 564 KLLMDKCFHR-LLDGKMRILVTHHVQLLKS--VDQLLLLEG 601
>At4g01820 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1229
Score = 51.2 bits (121), Expect = 4e-06
Identities = 49/202 (24%), Positives = 91/202 (44%), Gaps = 38/202 (18%)
Query: 352 AFTY---PDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ- 407
+FTY PD++ + D + AG Q + ++GE+G+GK+T+I LL D G
Sbjct: 990 SFTYQTRPDVQIFR-DLCFAIRAG-----QTVALVGESGSGKSTVISLLQRFYDPDSGHI 1043
Query: 408 -----DIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFL-----NPQFQTDVVKPLKI- 456
++ KL + Q++ G LF IR+ + + +++ ++
Sbjct: 1044 TLDRVELKKLQLKWVRQQMG--LVGQEPVLFNDTIRSNIAYGKGGDEASEAEIIAAAELA 1101
Query: 457 -------------DDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRI 503
D ++ + LSGG+ QRVAI ++ I L+DE ++ LD+E
Sbjct: 1102 NAHGFISSIQQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESER 1161
Query: 504 ICSKVIRRFILHNKKTAFIVEH 525
+ + R +++ +T +V H
Sbjct: 1162 VVQDALDRVMVN--RTTVVVAH 1181
>At2g41700 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 1850
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/178 (21%), Positives = 83/178 (45%), Gaps = 18/178 (10%)
Query: 376 DSQILVMMGENGTGKTTLIKLLAGAIPADDGQDI--------------PKLNVSMKPQKI 421
++QIL ++G NG GK+T I +L G +P G + +L V + +
Sbjct: 511 ENQILSLLGHNGAGKSTTISMLVGLLPPTSGDALILGNSIITNMDEIRKELGVCPQHDIL 570
Query: 422 APKFTGTVRQLFFKRIRAQFLNPQFQT--DVVKPLKIDDIIDQEVQHLSGGELQRVAIVL 479
P+ T F ++ T D+ + + + D I+ V+ LSGG +++++ +
Sbjct: 571 FPELTVREHLEMFAVLKGVEEGSLKSTVVDMAEEVGLSDKINTLVRALSGGMKRKLSLGI 630
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKV 537
+L N+ + ++DEP++ +D + ++I++ + + + H A L D++
Sbjct: 631 ALIGNSKVIILDEPTSGMDPYSMRLTWQLIKK--IKKGRIILLTTHSMDEAEELGDRI 686
>At2g07680 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1146
Score = 51.2 bits (121), Expect = 4e-06
Identities = 75/318 (23%), Positives = 139/318 (43%), Gaps = 38/318 (11%)
Query: 250 SYLDVKQRLNAALIIRSLLNPTTYVICVEHDLSVLDYLSD----FVCIIYGVPSVYGVVT 305
++L ++ L+A + PT + +C +++ + D F C+ + + +
Sbjct: 206 THLATRKYLDAWCVFFWATTPTLFSLCTFGLFALMGHQLDAATVFTCLALFNSLISPLNS 265
Query: 306 LPSSVREGINIFLDGHIPSENLRFRTEALQFRMADAGDELE------ADASRAFTY---P 356
P + I+ F+ S+ L + F + D+G E DAS ++
Sbjct: 266 FPWVINGLIDAFISTRRVSKFLCCLEHSRDFSI-DSGFTSEDLAVCVEDASCTWSSNVEE 324
Query: 357 DMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSM 416
D T SL V G F + ++GE G+GKT+L+ L G + G + +V+
Sbjct: 325 DYNLTIKQVSLRVPKGSF-----VAVIGEVGSGKTSLLNSLLGEMRCVHGSILLNGSVAY 379
Query: 417 KPQKIAPKFTGTVRQ--LFFKRIRAQFLNPQFQTDVVKPLKID---------DIIDQEVQ 465
PQ + +GTVR+ LF K ++ F+T L +D I +
Sbjct: 380 VPQ-VPWLLSGTVRENILFGKPFDSK---RYFETLSACALDVDISLMVGGDMACIGDKGL 435
Query: 466 HLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFI--LHNKKTAFIV 523
+LSGG+ R A+ ++ +D+YL+D+ + +DS+ + C + R + L NKKT +
Sbjct: 436 NLSGGQRARFALARAVYHGSDMYLLDDVLSAVDSQ--VGCWILQRALLGPLLNKKTRVMC 493
Query: 524 EHDFIMATYLADKVIVFD 541
H+ ++ ++V D
Sbjct: 494 THNIQVSNLSTHMIVVMD 511
>7299468 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1307
Score = 51.2 bits (121), Expect = 4e-06
Identities = 44/174 (25%), Positives = 83/174 (47%), Gaps = 15/174 (8%)
Query: 378 QILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAP-KFTGTVRQLFF-- 434
+++ ++G G GK++LI+ + G +P + G ++N S P FTGTVRQ
Sbjct: 442 KLVAVIGPVGAGKSSLIQAILGELPGESGT--LRINGSYSYAAQEPWLFTGTVRQNILFG 499
Query: 435 -----KRIRAQFLNPQFQTDV-VKPLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIY 488
R R + D + P I+ + LSGG+ R+++ ++ ADIY
Sbjct: 500 LDWDKHRYRTVVKKCALERDFELLPFGDKTIVGERGASLSGGQKARISLARAVYRRADIY 559
Query: 489 LIDEPSAYLDSE-QRIICSKVIRRFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
L+D+P + +D+ R + + +R ++ + +V H + AD +++ D
Sbjct: 560 LLDDPLSAVDTHVGRHLFDQCMRGYL--RSELVILVTHQ-LQFLEQADLIVIMD 610
>7296258 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 643
Score = 51.2 bits (121), Expect = 4e-06
Identities = 45/176 (25%), Positives = 77/176 (43%), Gaps = 11/176 (6%)
Query: 104 QVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKMLEDD 163
++ ++G +G GK+T L +LAG F E EI+ +++ F KM
Sbjct: 87 ELTAIIGPSGAGKTTLLNLLAG--------FGAVCESGEILVNNSPRDMR-VFRKMSRYI 137
Query: 164 IKAIIKPQYVDNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDILQLKNVLNREVSALS 223
++ + + I K+G+ +L L++ + + +L+LK+ LN LS
Sbjct: 138 MQTDVLDSQFTVLEMMILAANLKLGK--ELNLKQKLEVIDEILGMLRLKDTLNTMAQKLS 195
Query: 224 GGELQRFAIGMSCVQEADVYMFDEPSSYLDVKQRLNAALIIRSLLNPTTYVICVEH 279
GGE +R I + V V DEP++ LD +++ L VIC H
Sbjct: 196 GGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIH 251
>Hs14550412 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 2436
Score = 50.8 bits (120), Expect = 6e-06
Identities = 44/182 (24%), Positives = 83/182 (45%), Gaps = 22/182 (12%)
Query: 376 DSQILVMMGENGTGKTTLIKLLAGAIPADDG------------QDIPKLNVSMKPQK--I 421
++Q++ +G NG GKTT + +L G P G D + N+ M PQ +
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVL 1076
Query: 422 APKFTGTVRQLFFKRIR--AQFLNPQFQTDVVKPLKIDDIIDQEVQHLSGGELQRVAIVL 479
+ T F+ R++ AQ + +++ L++ + VQ LSGG +++++ +
Sbjct: 1077 FDRLTVEEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAI 1136
Query: 480 SLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNK--KTAFIVEHDFIMATYLADKV 537
+ + ++DEP+A +D R + I IL K +T + H A L D++
Sbjct: 1137 AFVGGSRAIILDEPTAGVDPYAR----RAIWDLILKYKPGRTILLSTHHMDEADLLGDRI 1192
Query: 538 IV 539
+
Sbjct: 1193 AI 1194
>At3g55320 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1408
Score = 50.8 bits (120), Expect = 6e-06
Identities = 55/214 (25%), Positives = 95/214 (43%), Gaps = 32/214 (14%)
Query: 353 FTYPDMKR--TQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL-------AGAIPA 403
F YP +FSL + G Q + ++G +G+GK+T+I L+ AG +
Sbjct: 1166 FCYPTRPEILVLSNFSLKISGG-----QTVAVVGVSGSGKSTIISLVERYYDPVAGQVLL 1220
Query: 404 DDGQDIPKLNVSMKP------QKIAPKFTGTVRQ-LFFKRIRAQFLNPQFQTDVVK---- 452
D G+D+ N+ Q+ F+ T+R+ + + R A + +
Sbjct: 1221 D-GRDLKLYNLRWLRSHMGLVQQEPIIFSTTIRENIIYARHNASEAEMKEAARIANAHHF 1279
Query: 453 ----PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKV 508
P D I L+ G+ QR+AI + NA I LIDE S+ ++SE + +
Sbjct: 1280 ISSLPHGYDTHIGMRGVELTPGQKQRIAIARVVLKNAPIILIDEASSSIESESSRVVQEA 1339
Query: 509 IRRFILHNKKTAFIVEHDFIMATYLADKVIVFDG 542
+ I+ N KT ++ H M ++ D ++V +G
Sbjct: 1340 LDTLIMGN-KTTILIAHRAAMMRHV-DNIVVLNG 1371
>At1g10680 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1227
Score = 50.8 bits (120), Expect = 6e-06
Identities = 53/202 (26%), Positives = 95/202 (46%), Gaps = 42/202 (20%)
Query: 353 FTYPDMKRTQ--GDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL-------AGAIPA 403
F+YP DF+L V +G+ + ++G++G+GK++++ L+ AG I
Sbjct: 989 FSYPSRPDVTIFSDFNLLVPSGKS-----MALVGQSGSGKSSVLSLVLRFYDPTAGIIMI 1043
Query: 404 DDGQDIPKLNVSMKPQKIAPKFTGTVRQ---LFFKRIRAQFLNPQ---FQTDVVKPLKID 457
D GQDI KL + K + G V+Q LF I L + +++V++ K+
Sbjct: 1044 D-GQDIKKLKL-----KSLRRHIGLVQQEPALFATTIYENILYGKEGASESEVMEAAKLA 1097
Query: 458 DI--------------IDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRI 503
+ + + +SGG+ QR+AI ++ N +I L+DE ++ LD E
Sbjct: 1098 NAHSFISSLPEGYSTKVGERGIQMSGGQRQRIAIARAVLKNPEILLLDEATSALDVESER 1157
Query: 504 ICSKVIRRFILHNKKTAFIVEH 525
+ + + R L +T +V H
Sbjct: 1158 VVQQALDR--LMRDRTTVVVAH 1177
>7295351 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1302
Score = 50.8 bits (120), Expect = 6e-06
Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 29/194 (14%)
Query: 101 RPGQVLGLVGTNGIGKSTALKILAGKQKPNLGRFEDPPEWQEIIKYFRGSELQNYFTKML 160
R GQ + LVG++G GKST +++L RF DP ++ +++ Y + L
Sbjct: 431 RAGQTVALVGSSGCGKSTCVQLLQ--------RFYDPVFGSVLLDDL---DIRKYNIQWL 479
Query: 161 EDDIKAIIKPQYV------DNIPRAIKGPVQKVGELLKLRLEKSKDDAKRYIDIL--QLK 212
+I + + + NI G QK ++ ++ A +I L +
Sbjct: 480 RSNIAVVGQEPVLFLGTIAQNISYGKPGATQK-----EIEAAATQAGAHEFITNLPESYR 534
Query: 213 NVLNREVSALSGGELQRFAIGMSCVQEADVYMFDEPSSYLDV--KQRLNAALIIRSLLNP 270
+++ S LSGG+ QR AI + +Q + + DE +S LD ++++ AL + S
Sbjct: 535 SMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQQALDLASKGRT 594
Query: 271 TTYVICVEHDLSVL 284
T I V H LS +
Sbjct: 595 T---IVVSHRLSAI 605
>YMR301c [U] KOG0057 Mitochondrial Fe/S cluster exporter ABC superfamily
Length = 690
Score = 50.4 bits (119), Expect = 8e-06
Identities = 59/211 (27%), Positives = 93/211 (43%), Gaps = 34/211 (16%)
Query: 355 YPDMKRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQ------- 407
+PD K + + S T+ AG + ++G +G+GK+T++KL+ + G+
Sbjct: 446 HPDRKILK-NASFTIPAGWKT-----AIVGSSGSGKSTILKLVFRFYDPESGRILINGRD 499
Query: 408 ----DIPKLN--VSMKPQKIAPKFTGTV-RQLFFKRIRAQFLNPQFQTDVVK-------- 452
DI L + + PQ P F T+ + F RI A + + T V K
Sbjct: 500 IKEYDIDALRKVIGVVPQD-TPLFNDTIWENVKFGRIDAT--DEEVITVVEKAQLAPLIK 556
Query: 453 --PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIR 510
P D I+ + +SGGE QR+AI L NA I DE ++ LD+ + IR
Sbjct: 557 KLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIR 616
Query: 511 RFILHNKKTAFIVEHDFIMATYLADKVIVFD 541
+T+ + H + ADK+IV D
Sbjct: 617 DNFTSGSRTSVYIAHR-LRTIADADKIIVLD 646
>CE03261 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1291
Score = 50.4 bits (119), Expect = 8e-06
Identities = 46/155 (29%), Positives = 75/155 (47%), Gaps = 21/155 (13%)
Query: 378 QILVMMGENGTGKTTLIKLL------AGAIPADDGQDIPKLNVSMKPQKIA-----PK-F 425
Q + ++G +G+GK+T I +L G DGQDI +++ ++A P+ F
Sbjct: 1079 QTVALVGPSGSGKSTCIGMLERFYDVTGGALRMDGQDIKNISLYHLRTQMALVGQEPRLF 1138
Query: 426 TGTVRQ---LFFKRIRAQFLNPQFQTDVVKPL--KIDDIIDQEVQH----LSGGELQRVA 476
GT+R+ L K + + +N + + D ID EV LSGG+ QR+A
Sbjct: 1139 VGTIRENVCLGLKDVPLEKINQALELANANRFLGNLPDGIDTEVGERGGQLSGGQKQRIA 1198
Query: 477 IVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRR 511
I +L + I L+DE ++ LDSE + + R
Sbjct: 1199 IARALVRDPKILLLDEATSALDSESERAVQEALDR 1233
>At3g55100 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 662
Score = 50.4 bits (119), Expect = 8e-06
Identities = 50/209 (23%), Positives = 89/209 (41%), Gaps = 26/209 (12%)
Query: 372 GEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIPKLNVSMKPQKIAPKFTGTVRQ 431
GE + +IL ++G +G GK+TLI LAG I + LN ++ + V Q
Sbjct: 57 GEAKEGEILAILGASGAGKSTLIDALAGQIAEGSLKGTVTLNGEALQSRLLRVISAYVMQ 116
Query: 432 --LFFKRI--------RAQFLNPQFQTDVVKPLKIDDIIDQ------------EVQH--L 467
L F + A+F P+ + K +++ +IDQ + H +
Sbjct: 117 EDLLFPMLTVEETLMFAAEFRLPRSLSKSKKRNRVETLIDQLGLTTVKNTVIGDEGHRGV 176
Query: 468 SGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDF 527
SGGE +RV+I + + + +DEP++ LDS + +V+++ +
Sbjct: 177 SGGERRRVSIGTDIIHDPIVLFLDEPTSGLDSTSAFMVVQVLKKIARSGSIVIMSIHQPS 236
Query: 528 IMATYLADKVIVFDGIPSKQAFARAPESL 556
D+VIV + F+ +P +L
Sbjct: 237 GRIMEFLDRVIVLSS--GQIVFSDSPATL 263
>Hs5031915 [Q] KOG0054 Multidrug resistance-associated protein/mitoxantrone
resistance protein ABC superfamily
Length = 1325
Score = 50.1 bits (118), Expect = 1e-05
Identities = 67/266 (25%), Positives = 113/266 (42%), Gaps = 30/266 (11%)
Query: 300 VYGVVTLPSSVREGINIFLDGHIP--SENL----RFRTEALQFRMADAGDELEADASRAF 353
V+ VTL +VR + +F I SE + R +T L ++ +L +D +
Sbjct: 351 VFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKKMV 410
Query: 354 TYPDMKR---------TQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPAD 404
D T S TV GE +L ++G G GK++L+ + G +
Sbjct: 411 HVQDFTAFWDKASETPTLQGLSFTVRPGE-----LLAVVGPVGAGKSSLLSAVLGELAPS 465
Query: 405 DGQDIPKLNVSMKPQKIAPKFTGTVRQ--LFFKRIRAQFLNPQFQTDVVKP----LKIDD 458
G ++ Q+ F+GT+R LF K+ + + +K L+ D
Sbjct: 466 HGLVSVHGRIAYVSQQ-PWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGD 524
Query: 459 --IIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHN 516
+I LSGG+ RV + ++ +ADIYL+D+P + +D+E ++ ILH
Sbjct: 525 LTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHE 584
Query: 517 KKTAFIVEHDFIMATYLADKVIVFDG 542
K T +V H + +I+ DG
Sbjct: 585 KIT-ILVTHQLQYLKAASQILILKDG 609
>CE24868 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1239
Score = 50.1 bits (118), Expect = 1e-05
Identities = 54/199 (27%), Positives = 83/199 (41%), Gaps = 36/199 (18%)
Query: 353 FTYPDM--KRTQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKLL-------AGAIPA 403
F YP + FSL + G + ++G +G GK+T+I +L AG I
Sbjct: 1006 FAYPSTPHRNVCEGFSLNIPKGHS-----IALVGASGCGKSTIISMLERFYSAKAGRISV 1060
Query: 404 DDGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQFLNPQFQTDVVK----------- 452
DD DI ++V+ I+ G LF IR + V +
Sbjct: 1061 DDN-DIDGIDVNHLRNNIS--VVGQEPVLFNATIRENITIGIDEVSVEEVQKACKAANAA 1117
Query: 453 ------PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICS 506
PL D I+ + LSGG+ QR+AI ++ I L+DE ++ LD++ I
Sbjct: 1118 GFIESFPLGYDTIVGEGGASLSGGQKQRIAIARAIIRKPKILLLDEATSALDTQSEEIVQ 1177
Query: 507 KVIRRFILHNKKTAFIVEH 525
K +R +T+ IV H
Sbjct: 1178 KALRS--ATTGRTSIIVAH 1194
>CE03818 [Q] KOG0055 Multidrug/pheromone exporter ABC superfamily
Length = 1268
Score = 50.1 bits (118), Expect = 1e-05
Identities = 60/213 (28%), Positives = 91/213 (42%), Gaps = 37/213 (17%)
Query: 353 FTYPDMKR--TQGDFSLTVEAGEFSDSQILVMMGENGTGKTTLIKL-------LAGAIPA 403
F YP+ +R F+++ G Q + ++G +G GK+T I+L L G++
Sbjct: 1036 FAYPNRRRQLVLDGFNMSANFG-----QTVALVGPSGCGKSTTIQLIERYYDALCGSVKI 1090
Query: 404 DDGQDIPKLNVSMKPQKIAPKFTGTVRQLFFKRIRAQF---LNPQFQTDVVK-------- 452
DD DI L+V IA G LF IR L Q V K
Sbjct: 1091 DDS-DIRDLSVKHLRDNIA--LVGQEPTLFNLTIRENITYGLENITQDQVEKAATLANIH 1147
Query: 453 ------PLKIDDIIDQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICS 506
P D + LSGG+ QRVAI ++ + I L+DE ++ LD+E I
Sbjct: 1148 TFVMGLPDGYDTSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQ 1207
Query: 507 KVIRRFILHNKKTAFIVEHDFIMATYLADKVIV 539
+ + + L +T ++ H + ADK+IV
Sbjct: 1208 EALDKARL--GRTCVVIAHR-LSTIQNADKIIV 1237
>At3g47740 [IR] KOG0059 Lipid exporter ABCA1 and related proteins ABC
superfamily
Length = 925
Score = 50.1 bits (118), Expect = 1e-05
Identities = 51/193 (26%), Positives = 82/193 (42%), Gaps = 25/193 (12%)
Query: 366 SLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDG----------QDIPKLNVS 415
SL V +GE M+G NG GKT+ I ++ G + G +D+ ++ S
Sbjct: 628 SLAVPSGE-----CFGMLGPNGAGKTSFINMMTGLVKPTSGAAFVQGLDICKDMDRVYTS 682
Query: 416 MK--PQK--IAPKFTGTVRQLFF---KRIRAQFLNPQFQTDVVKP-LKIDDIIDQEVQHL 467
M PQ + TG LF+ K ++ LN + + L + D+
Sbjct: 683 MGVCPQHDLLWETLTGREHLLFYGRLKNLKGVDLNQAVEESLRSVNLFHGGVADKPAGKY 742
Query: 468 SGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQRIICSKVIRRFILHNKKTAFIVEHDF 527
SGG +R+++ +SL N + +DEPS LD R VI+ H + H
Sbjct: 743 SGGMKRRLSVAISLIGNPKVVYMDEPSTGLDPASRKNLWTVIKNAKRHT--AIILTTHSM 800
Query: 528 IMATYLADKVIVF 540
A +L D++ +F
Sbjct: 801 EEAEFLCDRLGIF 813
>At2g01320 [Q] KOG0061 Transporter ABC superfamily (Breast cancer resistance
protein)
Length = 725
Score = 50.1 bits (118), Expect = 1e-05
Identities = 42/162 (25%), Positives = 75/162 (45%), Gaps = 25/162 (15%)
Query: 365 FSLTVEAGEFSDSQILVMMGENGTGKTTLIKLLAGAIPADDGQDIP-KLNVSMKPQKIAP 423
F L +GE ++L +MG +G+GKTTL+ +LAG + + L V+ KP
Sbjct: 89 FLLKNVSGEAKPGRLLAIMGPSGSGKTTLLNVLAGQLSLSPRLHLSGLLEVNGKPSSSKA 148
Query: 424 KFTGTVRQ--LFFKRI--------RAQFLNPQFQTDVVKPLKIDDII------------- 460
VRQ LFF ++ A+ P+ + + +++++
Sbjct: 149 YKLAFVRQEDLFFSQLTVRETLSFAAELQLPEISSAEERDEYVNNLLLKLGLVSCADSCV 208
Query: 461 -DQEVQHLSGGELQRVAIVLSLGMNADIYLIDEPSAYLDSEQ 501
D +V+ +SGGE +R+++ L + + DEP+ LD+ Q
Sbjct: 209 GDAKVRGISGGEKKRLSLACELIASPSVIFADEPTTGLDAFQ 250
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.139 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,063,155
Number of Sequences: 60738
Number of extensions: 1675907
Number of successful extensions: 6751
Number of sequences better than 1.0e-05: 108
Number of HSP's better than 0.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 6194
Number of HSP's gapped (non-prelim): 444
length of query: 607
length of database: 30,389,216
effective HSP length: 112
effective length of query: 495
effective length of database: 23,586,560
effective search space: 11675347200
effective search space used: 11675347200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)