ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4482 good DL KOG1970 Cell cycle control, cell division, chromosome partitioning Checkpoint RAD17-RFC complex, RAD17/RAD24 component
r_klactIII4482 good DL KOG1970 Replication, recombination and repair Checkpoint RAD17-RFC complex, RAD17/RAD24 component
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4482 1586564 1588507 648
(648 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YER173w [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 co... 394 e-109
SPAC14C4.13 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD2... 95 3e-19
Hs4506383 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 ... 85 4e-16
Hs19718786 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24... 85 4e-16
7299911 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 co... 79 2e-14
Hs19718790 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24... 74 7e-13
At5g66130 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 ... 74 7e-13
CE17738 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 co... 57 9e-08
>YER173w [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 659
Score = 394 bits (1011), Expect = e-109
Identities = 245/614 (39%), Positives = 354/614 (56%), Gaps = 46/614 (7%)
Query: 62 QWYDKFSPKRVDDIALHKKKIEEVRYYLEGMVSGKSDERILLLSGPAGCSKSTCVKLISD 121
QWY+KF P ++ +A+HK+K+++V+ L+ M + RILLLSGP+GCSKST +K +S
Sbjct: 65 QWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHRILLLSGPSGCSKSTVIKELSK 124
Query: 122 EIVPRYRATSGLTVSGREVPN---FTEYLTD--MSSVSPSESFDDFLLQSKYLIGRNLSV 176
+VP+YR S T S R PN TE+ D ++ + ESF +FL ++YL+ NLS+
Sbjct: 125 ILVPKYRQNSNGT-SFRSTPNEHKVTEFRGDCIVNDLPQMESFSEFLKGARYLVMSNLSL 183
Query: 177 LLVEDLPNVFHESTLKRFRESILSWLFASDRL-PPLVICLTECQLLDSNSTNSSFGIDST 235
+L+EDLPNVFH T +RF++ IL WL++S+ L PPLVIC+TEC++ ++++ FGID T
Sbjct: 184 ILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICITECEIPENDNNYRKFGIDYT 243
Query: 236 FISETILGKDILMHPLLHRIKFNPINATLMTKHLKQI-IQKVRREIPSEKYQRSGTFIKN 294
F +ETI+ K+ILMHP L RIKFNPIN+TL+ KHLK I +Q ++ K+ + I
Sbjct: 244 FSAETIMNKEILMHPRLKRIKFNPINSTLLKKHLKFICVQNMKMLKEKNKWNKRQEVIDY 303
Query: 295 LASSTGDIRSGIAALQFWCTSSFDETNSIFTRESSTSYFHGIGKVIYGSKDNENDRYMIN 354
+A TGDIRS I LQFW TSS + I TRES+ SYFH IGKVI+GS ND MIN
Sbjct: 304 IAQETGDIRSAITTLQFWATSS--GSLPISTRESTISYFHAIGKVIHGSHSTNNDNEMIN 361
Query: 355 ELVDGGT--IANDTFKLGILENFSKLNKSQFPLHYAADVVDTLSITDTLRPLEEEPLYYC 412
L + ++ + FKLGILEN++ NK +F + A+ +VD LS D + L E Y
Sbjct: 362 NLFENSNNLLSKEDFKLGILENYNTFNKGEFSISDASSIVDCLSECDNMNGLPESN-EYG 420
Query: 413 LGKVRNISSDVKSSNHSVHGQANFPREYKMVQEQKRFQFQLQDFIAVEFYKYHSLWSTKD 472
L +VR ++ H+ HG FPRE+K+ + Q F+ Q +D++ V YKY+++ S ++
Sbjct: 421 LREVRKTFRNISKQGHN-HGTVYFPREWKVRKLQNSFKVQAEDWLNVSLYKYNAVHSFRN 479
Query: 473 AVLYGSYFGPEIRKFLSFKAKSLKYYIDSL-------KPTTEQYNDYMSKYRRXXXXXXX 525
L Y+ P IRK S+K K + YY+ +L K T ++++D M
Sbjct: 480 ITLEFGYYAPLIRKCQSYKKKYILYYLKNLPSGSSGPKQTMDKFSDIMK------VENGI 533
Query: 526 XXXERVGGEMRMMHATSELTTSLDDSKS-----ENLALTNERNLEXXXXXXXXXXXDEDP 580
+R+GG + + L +D+ + E+ +R L +
Sbjct: 534 DVVDRIGGPIEALSVEDGLAPLMDNDSNNCDHLEDQKKERDRRLRMLIDQYERNVMMAND 593
Query: 581 STLPDNHDFKDDPIVDSDSEPA--IGLEV---EEGDSELYEILSQR-PKQTKFNGTQNSI 634
+ F DDPIVDSDS+ + IG E + D L EILSQR P++ I
Sbjct: 594 DLEDEETSFNDDPIVDSDSDNSNNIGNETFGRSDEDESLCEILSQRQPRKAPV------I 647
Query: 635 NEDVPLSDSDIENL 648
+E LSDSD+E L
Sbjct: 648 SES--LSDSDLEIL 659
>SPAC14C4.13 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 606
Score = 95.1 bits (235), Expect = 3e-19
Identities = 81/280 (28%), Positives = 145/280 (50%), Gaps = 27/280 (9%)
Query: 63 WYDKFSPKRVDDIALHKKKIEEVRYYLEGMVSGKSDERILLLSGPAGCSKSTCVKLISDE 122
W++K+ P++ D+A+HK KI ++ + M++ + R+LL+ GP+GC KST V++++ E
Sbjct: 72 WFEKYIPQKAADLAVHKSKISAIKQW---MLTDSLESRLLLICGPSGCGKSTAVQVLAKE 128
Query: 123 IVPRYRATSGLTVSGREVPNFTE----YLTDMSS--VSPSESFDDFLLQSKYLI---GRN 173
+ Y L + P+ E LT+ S +S E++ + L I G+N
Sbjct: 129 L--GYSLIEWLNPMNLKEPSNQESDTLSLTEKFSRFMSLCETYPELELMDSNNIQKRGKN 186
Query: 174 L----SVLLVEDLPNVF-HESTLKRFRESILSWLFASDRLPPLVICLTECQLLDSNSTNS 228
+ ++++P++ +L FR I + L + +++ LTE QL + NS
Sbjct: 187 AQGKKKFIFLDEIPHLSKFNGSLDAFRNVIRTALTSRGAF-SIIMVLTEIQLNNLEGINS 245
Query: 229 SFGIDSTFISETILGKDILMHPLLHRIKFNPINATLMTKHLKQIIQKVRREIPSEKYQRS 288
++F S I+G D+L P + ++FNPI T M K L I++K +P K +
Sbjct: 246 Q--DRNSFNSVQIMGNDLLQDPRVTVLQFNPIAPTYMKKCLGSILRK--EGVP--KSPKL 299
Query: 289 GTFIKNLAS-STGDIRSGIAALQFWCTSSFDETNSIFTRE 327
+ ++N+ S S GD+RS I +LQ + SF++ + RE
Sbjct: 300 LSLVENICSASEGDLRSAINSLQLSISQSFEKKGTKNIRE 339
>Hs4506383 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 670
Score = 84.7 bits (208), Expect = 4e-16
Identities = 81/278 (29%), Positives = 131/278 (46%), Gaps = 37/278 (13%)
Query: 63 WYDKFSPKRVDDIALHKKKIEEVRYYLEGMV---SGKSDERILLLSGPAGCSKSTCVKLI 119
W DK+ P+ ++A+HKKKIEEV +L+ V K ILL++GP GC K+T +K++
Sbjct: 80 WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 139
Query: 120 SDEIVPRYRATSGLTVSGREVPNFTEYLTDMSS--VSPSES----FDDFLLQ-SKY---- 168
S E + + + + +F SS + P +S F +FLL+ +KY
Sbjct: 140 SKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQ 199
Query: 169 LIGRNL----SVLLVEDLPNVFHESTLKRFRESILSWLFASDRLPPLVICLTECQLLDSN 224
++G +L ++LVEDLPN F+ + +L R PL+ +++ D+N
Sbjct: 200 MLGDDLRTDKKIILVEDLPNQFYRDS--HTLHEVLRKYVRIGRC-PLIFIISDSLSGDNN 256
Query: 225 STNSSFGIDSTFISETILGKDILMHPLLHRIKFNPINATLMTKHLKQIIQKVRREIPSEK 284
+ K+I + I FNP+ T+M K L +I+ + +
Sbjct: 257 -------------QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKI 303
Query: 285 YQRSGTFIKNLASS-TGDIRSGIAALQFWCTSSFDETN 321
T ++ L +GDIRS I +LQF +SS E N
Sbjct: 304 TVPDKTSLELLCQGCSGDIRSAINSLQF--SSSKGENN 339
>Hs19718786 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 681
Score = 84.7 bits (208), Expect = 4e-16
Identities = 81/278 (29%), Positives = 131/278 (46%), Gaps = 37/278 (13%)
Query: 63 WYDKFSPKRVDDIALHKKKIEEVRYYLEGMV---SGKSDERILLLSGPAGCSKSTCVKLI 119
W DK+ P+ ++A+HKKKIEEV +L+ V K ILL++GP GC K+T +K++
Sbjct: 91 WVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKIL 150
Query: 120 SDEIVPRYRATSGLTVSGREVPNFTEYLTDMSS--VSPSES----FDDFLLQ-SKY---- 168
S E + + + + +F SS + P +S F +FLL+ +KY
Sbjct: 151 SKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQ 210
Query: 169 LIGRNL----SVLLVEDLPNVFHESTLKRFRESILSWLFASDRLPPLVICLTECQLLDSN 224
++G +L ++LVEDLPN F+ + +L R PL+ +++ D+N
Sbjct: 211 MLGDDLRTDKKIILVEDLPNQFYRDS--HTLHEVLRKYVRIGRC-PLIFIISDSLSGDNN 267
Query: 225 STNSSFGIDSTFISETILGKDILMHPLLHRIKFNPINATLMTKHLKQIIQKVRREIPSEK 284
+ K+I + I FNP+ T+M K L +I+ + +
Sbjct: 268 -------------QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKI 314
Query: 285 YQRSGTFIKNLASS-TGDIRSGIAALQFWCTSSFDETN 321
T ++ L +GDIRS I +LQF +SS E N
Sbjct: 315 TVPDKTSLELLCQGCSGDIRSAINSLQF--SSSKGENN 350
>7299911 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 520
Score = 79.3 bits (194), Expect = 2e-14
Identities = 89/323 (27%), Positives = 149/323 (45%), Gaps = 37/323 (11%)
Query: 27 KVKRSST-SVPSFPYT--NLDHVDLTRPSGERTL-----PSELQ--WYDKFSPKRVDDIA 76
+V RS T S+ + P ++D VDLT ++ P E++ W + F P DD+A
Sbjct: 28 RVSRSRTPSINTKPIQIPDVDSVDLTAMDDDQDADITVPPPEVKENWMESFEPATSDDLA 87
Query: 77 LHKKKIEEVRYYLE--GMVSGKSDERILLLSGPAGCSKSTCVKLISDEIVPRYRATSGLT 134
+H KK+ E+R +L V K ++ LL+GP G K+T +++++ E Y+ +
Sbjct: 88 VHPKKVGELRDWLRHCEAVRKKFPAQMCLLTGPTGAGKTTTLRVLAKEF--GYQLQEWIN 145
Query: 135 VSGREVPN-FTEYLTDMSSV-SPSESFDDFLLQ-SKY---LIGRNLSVLLVEDLPNVFHE 188
EV N + T S V S E+F FLL+ S+Y L +N +LLVED PNV
Sbjct: 146 PIDCEVVNTLGDQTTGASYVGSHLEAFKSFLLRASRYKSLLDSQNKRLLLVEDFPNVLLS 205
Query: 189 STLKRFRESILSWLFASDRLPPLVICLTECQLLDSNSTNSSFGIDSTFISETILGKDILM 248
F E + + + PLV + + + S N S+ + + + K +
Sbjct: 206 DKEVNFEELLEE--YTAYGKSPLVFIVADAK---SRGLNISYRL----FPDQLKAKHRIE 256
Query: 249 HPLLHRIKFNPINATLMTKHLKQIIQKVRREIPSEKYQRSGTFIKNLASSTGDIRSGIAA 308
H I FN I +T+M K +K +++ + K + + + GDIR+ +
Sbjct: 257 H-----ISFNAIASTIMQKSMKTFCSVMQQNKATYKVPSTAVVDSIVVGAQGDIRNALIN 311
Query: 309 LQFWCTSSFDETNSIFTRESSTS 331
L SS +S+ T++ + S
Sbjct: 312 LHL---SSLKGVSSMPTKQLNVS 331
>Hs19718790 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 584
Score = 73.9 bits (180), Expect = 7e-13
Identities = 76/267 (28%), Positives = 127/267 (47%), Gaps = 37/267 (13%)
Query: 74 DIALHKKKIEEVRYYLEGMVSGKSDER---ILLLSGPAGCSKSTCVKLISDEIVPRYRAT 130
++A+HKKKIEEV +L+ V + ++ ILL++GP GC K+T +K++S E + +
Sbjct: 5 ELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKILSKEHGIQVQEW 64
Query: 131 SGLTVSGREVPNFTEYLTDMSS--VSPSES----FDDFLLQ-SKY----LIGRNL----S 175
+ + +F SS + P +S F +FLL+ +KY ++G +L
Sbjct: 65 INPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKK 124
Query: 176 VLLVEDLPNVFHESTLKRFRESILSWLFASDRLPPLVICLTECQLLDSNSTNSSFGIDST 235
++LVEDLPN F+ + +L R PL+ +++ D+N
Sbjct: 125 IILVEDLPNQFYRDS--HTLHEVLRKYVRIGRC-PLIFIISDSLSGDNN----------- 170
Query: 236 FISETILGKDILMHPLLHRIKFNPINATLMTKHLKQIIQKVRREIPSEKYQRSGTFIKNL 295
+ K+I + I FNP+ T+M K L +I+ + + T ++ L
Sbjct: 171 --QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELL 228
Query: 296 ASS-TGDIRSGIAALQFWCTSSFDETN 321
+GDIRS I +LQF +SS E N
Sbjct: 229 CQGCSGDIRSAINSLQF--SSSKGENN 253
>At5g66130 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 599
Score = 73.9 bits (180), Expect = 7e-13
Identities = 80/343 (23%), Positives = 149/343 (43%), Gaps = 74/343 (21%)
Query: 54 ERTLPSELQWYDKFSPKRVDDIALHKKKIEEVRYYLE---GMVSGKSDERILLLSGPAGC 110
ER+ ++L W DK+ P+ ++++++HKKK++EV+ + + + +LL++G AG
Sbjct: 85 ERSKNTDL-WVDKYRPRTLEELSVHKKKVDEVKLWFQESLDFLKNGLRNNVLLVTGQAGV 143
Query: 111 SKSTCVKLISDEIVPRYRATSGLTVSGREVPNFT---EYLTDMSS----VSPSESFDDFL 163
KS + LI+ + G+TV P T E++ + SS S + F++F+
Sbjct: 144 GKSATIHLITSIL--------GVTVHEWNAPIPTIWQEHVHNTSSGLKYTSKLDEFENFV 195
Query: 164 LQS-KYLIGRNLS--------VLLVEDLPNVFHESTLKRFRESILSWLFASDRLPPLVIC 214
+ KY + + S VLL++DLP +R + +L L P VI
Sbjct: 196 ESTRKYGVMASSSTDGIKAPVVLLIDDLPLANGRHAFERLQNCLL--LLVKSTQIPTVIL 253
Query: 215 LTECQLLDSNSTNSSFGIDSTFISETILGKDILMHPLLHRIKFNPINATLMTKHLKQIIQ 274
+T+ DS+ + D+ + L ++ FNPI + K L++I +
Sbjct: 254 ITDHNNADSSDQTARRMEDT---------QSSLERAGALKVAFNPITKNSIKKVLQRICR 304
Query: 275 KVRREIPSEKYQRSGTFIKNLASSTGDIRSGIAALQFWCT-------------------- 314
+ ++ + + + T +S GDIR I +LQ +
Sbjct: 305 EEHCKVTTMEIDQMAT------ASGGDIRHAITSLQLFSVKPELNHTKIKSPRPGMEDNY 358
Query: 315 --------SSFDE-TNSIFTRESSTSYFHGIGKVIYGSKDNEN 348
S D +S F R+ + S FH +GK ++ ++ +N
Sbjct: 359 HGNEQTMYSGLDSGISSCFGRDETLSLFHALGKFLHNKRETDN 401
>CE17738 [DL] KOG1970 Checkpoint RAD17-RFC complex RAD17/RAD24 component
Length = 514
Score = 57.0 bits (136), Expect = 9e-08
Identities = 72/304 (23%), Positives = 129/304 (41%), Gaps = 63/304 (20%)
Query: 66 KFSPKRVDDIALHKKKIEEVRYYLEGMVSGKSDE-RILLLSGPAGCSKSTCVKLISDEIV 124
+ +P+R D++ +H KKI EV ++L+ + S + + ++ L+GPAG KST V+++ E
Sbjct: 12 ELAPRRRDELQIHNKKIAEVDHWLKNVFSESNKQLGVMYLTGPAGSGKSTTVEVMCTE-- 69
Query: 125 PRYRATSGLTVSGREVPNFT-EYL--TDMSSVSPSESFDDFLLQSKYLIGRNLS------ 175
E+ ++ EYL D P DF ++L+ R+ S
Sbjct: 70 -----------QNIEIIEYSPEYLHNEDFECEKP-----DFTQLRRFLLRRHGSLRGGGL 113
Query: 176 ---VLLVEDLPNVFHESTLKRFRESILSWLFASDRLPPLVICLTE---CQLLDSNSTNSS 229
+LLV +LP+ + S ++FRE + L P++ CLT C L+
Sbjct: 114 KKRLLLVTELPDQAY-SDAEKFREDLSEVL--QHIWHPVIFCLTNSIACWNLN------- 163
Query: 230 FGIDSTFISETILGKDILMHPLLHRIKFNPINATLMTKHLKQIIQKVRREIPSEKYQRSG 289
+ + KD + + + FNP+ + M K L + + + K G
Sbjct: 164 --------PDRLFTKDFNIMNGIDTVTFNPVADSFMKKALVRASNCLSSPLSDAKLNVIG 215
Query: 290 TFIKNLASSTGDIRSGIAALQ---FWCTSSFDETNSIF--TRESSTSYFHGIGKVIYGSK 344
+ GD+R + LQ + NS+ ++ + FH IG+++Y +
Sbjct: 216 ------EEAGGDLRIAMNMLQMNSIGPNADRRSGNSVICASKANREEAFHMIGRILYAKR 269
Query: 345 DNEN 348
N N
Sbjct: 270 VNPN 273
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,674,649
Number of Sequences: 60738
Number of extensions: 1633451
Number of successful extensions: 3666
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3636
Number of HSP's gapped (non-prelim): 10
length of query: 648
length of database: 30,389,216
effective HSP length: 113
effective length of query: 535
effective length of database: 23,525,822
effective search space: 12586314770
effective search space used: 12586314770
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)