ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4572 good D KOG2166 Cell cycle control, cell division, chromosome partitioning Cullins
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4572 1616252 1614048 -735
(735 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGR003w [D] KOG2166 Cullins 288 2e-77
At1g69670 [D] KOG2166 Cullins 223 1e-57
At1g26830 [D] KOG2166 Cullins 217 4e-56
SPAC24H6.03 [D] KOG2166 Cullins 213 1e-54
Hs4503165 [D] KOG2166 Cullins 212 2e-54
7298217 [D] KOG2166 Cullins 208 2e-53
Hs13270467 [D] KOG2167 Cullins 187 6e-47
CE27593 [D] KOG2166 Cullins 180 8e-45
At1g43140 [D] KOG2166 Cullins 164 6e-40
Hs11140811 [D] KOG2167 Cullins 162 1e-39
At4g02570 [D] KOG2166 Cullins 155 3e-37
At1g02980 [D] KOG2166 Cullins 149 1e-35
CE24979 [D] KOG2167 Cullins 147 4e-35
7304097 [D] KOG2167 Cullins 135 2e-31
7304137 [D] KOG2166 Cullins 132 1e-30
At5g46210 [D] KOG2167 Cullins 130 7e-30
Hs4503161 [D] KOG2166 Cullins 130 9e-30
Hs19482174 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component 127 8e-29
SPAC17G6.12 [D] KOG2166 Cullins 124 5e-28
SPAC3A11.08 [D] KOG2167 Cullins 121 3e-27
7302125 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component 116 1e-25
YDL132w [D] KOG2166 Cullins 111 5e-24
7301740 [O] KOG2285 E3 ubiquitin ligase Cullin 1 component 100 1e-20
Hs4503167 [O] KOG2285 E3 ubiquitin ligase Cullin 1 component 97 1e-19
CE11928 [D] KOG2166 Cullins 95 4e-19
CE29089 [D] KOG2166 Cullins 94 1e-18
CE25691 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component 66 2e-10
CE24730 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component 64 8e-10
CE16729 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component 64 8e-10
7294516 [D] KOG2166 Cullins 60 1e-08
At1g59790 [D] KOG2166 Cullins 58 5e-08
ECU07g0860 [D] KOG2166 Cullins 55 5e-07
At1g59800 [D] KOG2166 Cullins 50 9e-06
>YGR003w [D] KOG2166 Cullins
Length = 744
Score = 288 bits (738), Expect = 2e-77
Identities = 209/742 (28%), Positives = 368/742 (49%), Gaps = 49/742 (6%)
Query: 24 EGLDEQWAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHFGK 83
E +E W ++ ID I+ + +LSFE++Y T+Y +VL K GP L+ RL L
Sbjct: 20 ESFEESWETVKYAIDHIYSDDMADLSFEQVYKTIYTIVLNKKGPILYNRLKDYLIQKLAL 79
Query: 84 VRTSF--DGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRL 141
+R + D E L + ++WE Q D+ +YMD VY K +V + L
Sbjct: 80 LRETIVKDNTHDYEFLGTMARLWEVQCHCFKITGDLMMYMDKVYCKPNRCMEVYDMCLDL 139
Query: 142 FLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDIL-KNAIAVLNSLELKEGMSSVFLM 200
F E+++ S +L S+L+ +I + R + S L K I ++ +L + S FL
Sbjct: 140 FRIEILQKCSSSLISALISDIERIRNLGSVDSEHTSLWKVLIGMMETLH--DNRDSFFLT 197
Query: 201 EFEPFLLDSTEAYY-KNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILK 259
+FEP L+ +TE YY K + +L+ + + + F + D+ K
Sbjct: 198 DFEPVLISATEEYYNKAIDIELLTPIESLE------KIRKLRQFESMLDSSFLNVDSHNK 251
Query: 260 LHNIAERVLVTDNIQEIA--IYNVAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQLSQFI 317
L + E VL+ + +I + + A ++++ K +L + +SS +K + + + + +I
Sbjct: 252 LKTVLENVLIWGKLSDIIEDLTHEAMVISNGK--LLQEIYDLSSEEKYRVTVIESIKSYI 309
Query: 318 VKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCIN------- 370
K +I + W E+++L Y+ S L S + N
Sbjct: 310 NKNAINIPFNEGNRKKGQNAITWSSEIVEL---YRSQHSFLESIDFGSVRLNNLTGDVSN 366
Query: 371 ----EAFGKAFSQIKIFP-EFLSLYFDNYLK------SEPSAMDSNIRKCVQFFKLFKDK 419
+ F FS+ P E+LS Y D+ +K +E + ++ + L +K
Sbjct: 367 AILGDVFSMYFSKEGALPSEYLSTYVDHCMKRTKEKDAEIVKIKQDLLDSTKLIGLLTEK 426
Query: 420 DAFEIIYXXXXXXXXXXXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNTFMQ- 478
D FE IY V E+ ++ ++++ +GT +TSKL MLRD+ S+ Q
Sbjct: 427 DIFEKIYKKQLSRRLLQQRSLVEIEKWMVQMIKKVLGTFFTSKLEIMLRDISLSSEMYQA 486
Query: 479 -KNGKLSKTRDISV--NVLTNMFWPLQGSD-MNRDVIVPDSFAAIRNEYENRYAKTHSGR 534
++ ++ +S VLT WP Q ++ ++ + +P + I +E Y+ + R
Sbjct: 487 FQHSTINSIEYLSFAPQVLTRTSWPFQSTNPIDEGISLPPRMSQILAGFEGYYSLKYKER 546
Query: 535 LLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVR 594
+L+W +HLS +EI QF + Y+E+S +++G+IF+LF+++E LT EI ELT++P +V+
Sbjct: 547 VLKWAHHLSVIEIGCQFNSGYYEISFSVYAGVIFLLFEDYEELTLGEIYELTHIPIDDVK 606
Query: 595 KNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDS 654
++SMS P+ KIL+KS S S FS+N F++P RKVKV V+ P+ +D+
Sbjct: 607 SLVMSMSTIPRCKILKKS----SSSGNMKFSVNYFFSSPNRKVKV-PVIACPLPSQKSDN 661
Query: 655 TRSSVEKKLLDSRLSV-INAAVTRIMKQDRKLYHSELQDKVA-LSIPLFEMSPSLFKMSL 712
++ D+ + + ++A + RIMK + KL H +L ++ + ++PS+ K S+
Sbjct: 662 LATASSVDTYDNEIVMELSAIIVRIMKTEGKLSHQQLLERTTKRTQSRLSLTPSILKRSI 721
Query: 713 EYLLNNEYIQRDFDNTTMYHYL 734
+ L+ EYIQR+ D+ + YHYL
Sbjct: 722 QLLIEKEYIQRNADDPSYYHYL 743
>At1g69670 [D] KOG2166 Cullins
Length = 732
Score = 223 bits (567), Expect = 1e-57
Identities = 178/725 (24%), Positives = 324/725 (44%), Gaps = 36/725 (4%)
Query: 27 DEQWAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHFGKVRT 86
D+ W IL++ I +I++ + LSFE+LY Y +VL K G +L+ L ++ H ++
Sbjct: 26 DKTWKILEHAIHEIYNHNASGLSFEELYRNAYNMVLHKYGDKLYTGLVTTMTFHLKEICK 85
Query: 87 SFDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRLFLKEV 146
S + L LLN+ W L I D+ +YMD Y K V LG L+ V
Sbjct: 86 SIEEAQGGAFLELLNRKWNDHNKALQMIRDILMYMDRTYVSTTKKTHVHELGLHLWRDNV 145
Query: 147 V--EHVSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKEGMSSVFLMEFEP 204
V + L ++L+D ++ +E + +++N I + L SV+ +FE
Sbjct: 146 VYSSKIQTRLLNTLLDLVH--KERTGEVIDRVLMRNVIKMFMDLG-----ESVYQDDFEK 198
Query: 205 FLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIA 264
L+++ +YK + I D + + + D + K+ ++
Sbjct: 199 PFLEASAEFYKVESMEFIESCDCGEYLKKAEKPLVEEVERVV---NYLDAKSEAKITSVV 255
Query: 265 ERVLVTDNIQEIAIYNVAKIVN---SDKNDVLSRLLAISSSQKDKNVIFDQLSQFIVKEI 321
ER ++ +++Q + + +VN +DK + + R+ ++ + V + ++E+
Sbjct: 256 EREMIANHVQRLVHMENSGLVNMLLNDKYEDMGRMYSLFRRVANGLVTVRDVMTLHLREM 315
Query: 322 TSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQIK 381
+ ++Q L+ +DKY + + + +N +F +
Sbjct: 316 GKQLV--TDPEKSKDPVEFVQRLLDERDKYDRIINMAFNNDKTFQNALNSSFEYFVNLNT 373
Query: 382 IFPEFLSLYFDNYLKS-----EPSAMDSNIRKCVQFFKLFKDKDAFEIIY-XXXXXXXXX 435
PEF+SL+ D+ L+ +D + K + F+ ++KD FE Y
Sbjct: 374 RSPEFISLFVDDKLRKGLKGVGEEDVDLILDKVMMLFRYLQEKDVFEKYYKQHLAKRLLS 433
Query: 436 XXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNT----FMQKNGKLSKTRDISV 491
+ E+ LI L+ + G +TSKL GM D+ +S+ F + +LS+ + V
Sbjct: 434 GKTVSDDAERNLIVKLKTECGYQFTSKLEGMFTDMKTSHDTLLGFYNSHPELSEGPTLVV 493
Query: 492 NVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQF 551
VLT WP Q + +P + + ++ + Y TH+GR L W ++ T +I F
Sbjct: 494 QVLTTGSWPTQPTIQCN---LPAEVSVLCEKFRSYYLGTHTGRRLSWQTNMGTADIKAVF 550
Query: 552 -RNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQ 610
+ HEL++ F + MLF + L++ EI + T +P ++++ L SM+ +L+
Sbjct: 551 GKGQKHELNVSTFQMCVLMLFNNSDRLSYKEIEQATEIPTPDLKRCLQSMACVKGKNVLR 610
Query: 611 KSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSV 670
K P K I+ D F +N F + KVK+ V+ TR VE + R
Sbjct: 611 KEPMSKEIAEEDWFVVNDRFASKFYKVKIGTVVAQKETEPEKQETRQRVE----EDRKPQ 666
Query: 671 INAAVTRIMKQDRKLYHSELQDKVALSIPL-FEMSPSLFKMSLEYLLNNEYIQRDFDNTT 729
I AA+ RIMK R L H+ + +V + F +P+ K +E L+ ++++RD +
Sbjct: 667 IEAAIVRIMKSRRVLDHNNIIAEVTKQLQTRFLANPTEIKKRIESLIERDFLERDNTDRK 726
Query: 730 MYHYL 734
+Y YL
Sbjct: 727 LYRYL 731
>At1g26830 [D] KOG2166 Cullins
Length = 732
Score = 217 bits (553), Expect = 4e-56
Identities = 179/730 (24%), Positives = 324/730 (43%), Gaps = 46/730 (6%)
Query: 27 DEQWAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHFGKVRT 86
D+ W IL+ I +I++ + LSFE+LY Y +VL K G +L+ ++ H +
Sbjct: 26 DKTWQILERAIHQIYNQDASGLSFEELYRNAYNMVLHKFGEKLYTGFIATMTSHLKEKSK 85
Query: 87 SFDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRLFLKEV 146
+ L LN+ W + L I D+ +YMD Y + K V +G L+ V
Sbjct: 86 LIEAAQGGSFLEELNKKWNEHNKALEMIRDILMYMDRTYIESTKKTHVHPMGLNLWRDNV 145
Query: 147 VE--HVSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKEGMSSVFLMEFEP 204
V + L ++L+D + + R G +++N I + L SV+ +FE
Sbjct: 146 VHFTKIHTRLLNTLLDLVQKERIGEVIDRG--LMRNVIKMFMDLG-----ESVYQEDFEK 198
Query: 205 FLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIA 264
LD++ +YK + I D D+ + D + K+ ++
Sbjct: 199 PFLDASSEFYKVESQEFIESCD---CGDYLKKSEKRLTEEIERVAHYLDAKSEEKITSVV 255
Query: 265 ERVLVTDNIQEIAIYNVAKIVN---SDKNDVLSRLLAISSSQKD-----KNVIFDQLSQF 316
E+ ++ +++Q + + +VN +DK + L R+ + + ++V+ L +
Sbjct: 256 EKEMIANHMQRLVHMENSGLVNMLLNDKYEDLGRMYNLFRRVTNGLVTVRDVMTSHLREM 315
Query: 317 IVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKA 376
+ +T E ++Q L+ +DKY ++ + +N +F
Sbjct: 316 GKQLVTDPE-------KSKDPVEFVQRLLDERDKYDKIINTAFGNDKTFQNALNSSFEYF 368
Query: 377 FSQIKIFPEFLSLYFDNYL-KSEPSAMDSNIR----KCVQFFKLFKDKDAFEIIY-XXXX 430
+ PEF+SL+ D+ L K D ++ K + F+ ++KD FE Y
Sbjct: 369 INLNARSPEFISLFVDDKLRKGLKGITDVDVEVILDKVMMLFRYLQEKDVFEKYYKQHLA 428
Query: 431 XXXXXXXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNTFMQ----KNGKLSKT 486
+ E+ LI L+ + G +TSKL GM D+ +S M+ + +LS+
Sbjct: 429 KRLLSGKTVSDDAERSLIVKLKTECGYQFTSKLEGMFTDMKTSEDTMRGFYGSHPELSEG 488
Query: 487 RDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVE 546
+ V VLT WP Q + +P + + ++ + Y TH+GR L W ++ T +
Sbjct: 489 PTLIVQVLTTGSWPTQPA---VPCNLPAEVSVLCEKFRSYYLGTHTGRRLSWQTNMGTAD 545
Query: 547 IAYQF-RNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPK 605
I F + HEL++ F + MLF + L++ EI + T +P ++++ L S++
Sbjct: 546 IKAIFGKGQKHELNVSTFQMCVLMLFNNSDRLSYKEIEQATEIPAADLKRCLQSLACVKG 605
Query: 606 TKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLD 665
+++K P K I D+F +N FT+ KVK+ V+ TR VE +
Sbjct: 606 KNVIKKEPMSKDIGEEDLFVVNDKFTSKFYKVKIGTVVAQKETEPEKQETRQRVE----E 661
Query: 666 SRLSVINAAVTRIMKQDRKLYHSELQDKVALSI-PLFEMSPSLFKMSLEYLLNNEYIQRD 724
R I AA+ RIMK + L H+ + +V + P F +P+ K +E L+ ++++RD
Sbjct: 662 DRKPQIEAAIVRIMKSRKILDHNNIIAEVTKQLQPRFLANPTEIKKRIESLIERDFLERD 721
Query: 725 FDNTTMYHYL 734
+ +Y YL
Sbjct: 722 STDRKLYRYL 731
>SPAC24H6.03 [D] KOG2166 Cullins
Length = 785
Score = 213 bits (541), Expect = 1e-54
Identities = 191/795 (24%), Positives = 349/795 (43%), Gaps = 100/795 (12%)
Query: 17 RRYSRKTEGLDEQWAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERL--- 73
R++S W +LQ I IF ++LSFE+LY Y LVL K G +L+ +
Sbjct: 13 RKFSANQVDFATHWEVLQRAIGDIFQKSTSQLSFEELYRNAYILVLHKYGEKLYNHVQDV 72
Query: 74 --SRQLSDHFGKVRTSFDGITRAEAL-------------------------NLLNQVWEK 106
SR + + ++D AL +L+N W+
Sbjct: 73 IRSRLKEETVPAIYKNYDASLLGNALLDIRKNDSYSTSWSRSLEAAHRFLSSLVNS-WKD 131
Query: 107 QKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQA- 165
V + IS V Y+D VYSK +K V G +F +EVV S + V+ I
Sbjct: 132 HIVSMQMISSVLKYLDKVYSKSADKVPVNENGIYIF-REVVLLNSFEIGEKCVETILILV 190
Query: 166 -RESAAQYSGFDILKNAIAVLNSLELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIA- 223
E ++ + + +LNSL + +++ + F P L T +Y+ S +I
Sbjct: 191 YLERKGNTINRPLINDCLDMLNSLPSENKKETLYDVLFAPKFLSYTRNFYEIESSTVIGV 250
Query: 224 --------------EQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLV 269
E+++ R K++ + +D +L H
Sbjct: 251 FGVVEYLKKAEKRFEEEKERSKNYLFTKIASPLLSVV-------EDELLSKH-------- 295
Query: 270 TDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKDKNV--IFDQLSQFI------VKEI 321
D++ E +++S + L +L+ S S+ + V + L++++ + E
Sbjct: 296 LDDLLENQSTGFFSMIDSSNFEGL-QLVYESFSRVELGVKSLKKYLAKYVAHHGKLINET 354
Query: 322 TSIEIDTXXX-----XXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKA 376
TS ++ W+Q+++ L D+ + S A + +++AF
Sbjct: 355 TSQALEGKMAVGRLSSNATMATLWVQKVLALWDRLNTIISTTMDADRSILNSLSDAFVTF 414
Query: 377 FSQIKIFPEFLSLYFDNYLKSEP-----SAMDSNIRKCVQFFKLFKDKDAFEIIYXXXXX 431
PE++SL+ D+ LK + ++++ ++ V F+ +KD FE Y
Sbjct: 415 VDGYTRAPEYISLFIDDNLKKDARKAIEGSIEATLQNSVTLFRFISEKDVFEKYYKTHLA 474
Query: 432 XXXXXXXXNVLREQEL--IFLLQEDVGTSYTSKLRGMLRDLHSSNTFMQK---NGKLSKT 486
++ + EL I L+++ G +T KL GM D++ S +Q+ N L
Sbjct: 475 KRLLNNR-SISSDAELGMISRLKQEAGNVFTQKLEGMFNDMNLSQELLQEYKHNSALQSA 533
Query: 487 R---DISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLS 543
+ D++V++L + FWP+ S P A +++ + Y H+GR L W +
Sbjct: 534 KPALDLNVSILASTFWPIDLSPHKIKCNFPKVLLAQIDQFTDFYLSKHTGRKLLWYPSMG 593
Query: 544 TVEIAYQFRNSYHELSMPMFSGIIFMLF---KEHESLTFDEIVELTNLPQQEVRKNLISM 600
+ ++ F++ ++L++ + +I +LF KE++ L F+EI+E TN+ ++++NL S+
Sbjct: 594 SADVRVNFKDRKYDLNVSTIASVILLLFQDLKENQCLIFEEILEKTNIEVGDLKRNLQSL 653
Query: 601 SVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVE 660
+ A K KIL K P G+ ++ D F N+ F + ++K+ V + +DS R
Sbjct: 654 ACA-KYKILLKDPKGREVNAGDKFYFNENFVSNLARIKISTV---AQTRVEDDSERKRTL 709
Query: 661 KKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSI-PLFEMSPSLFKMSLEYLLNNE 719
+K+ +SR +A + R+MK + H++L +V + P F SP + K +E L+ E
Sbjct: 710 EKVDESRKHQADACIVRVMKDRKVCEHNQLMAEVTRQLNPRFHPSPMMIKRRIEALIERE 769
Query: 720 YIQRDFDNTTMYHYL 734
Y+QR DN +Y YL
Sbjct: 770 YLQRQADNGRIYEYL 784
>Hs4503165 [D] KOG2166 Cullins
Length = 768
Score = 212 bits (539), Expect = 2e-54
Identities = 190/749 (25%), Positives = 329/749 (43%), Gaps = 59/749 (7%)
Query: 30 WAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHF-GKVRTSF 88
W +L+N I +I + LSFE+LY Y +VL K+G +L+ L +++H KVR
Sbjct: 34 WDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDV 93
Query: 89 DGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRLFLKEVVE 148
L LNQ W + + I D+ +YMD VY ++ N +V +LG +F +VV
Sbjct: 94 LNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVR 153
Query: 149 H--VSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKEGMSSVFLMEFEPFL 206
+ + L+ +L+D I ARE + ++NA +L L L EG S V+ +FE
Sbjct: 154 YGCIRDHLRQTLLDMI--ARERKGEVVDRGAIRNACQMLMILGL-EGRS-VYEEDFEAPF 209
Query: 207 LDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAER 266
L+ + +++ + +AE + + + C ++ I+K + ER
Sbjct: 210 LEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVK---VVER 266
Query: 267 VLVTDNIQEIAIYNVAKIVNSDKN----DVLSRLLAISSSQKDKNVIFDQLSQFIVKEIT 322
L++ +++ I + +V+ KN D+ S + + +S ++ ++
Sbjct: 267 ELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGK 326
Query: 323 SIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQIKI 382
++ +IQ L+ LK ++ + + I F +
Sbjct: 327 AL---VSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSR 383
Query: 383 FPEFLSLYFDNYLKSEPSAM-----DSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXX 437
PE+LSL+ D+ LK + ++ + K + F+ ++KD FE Y
Sbjct: 384 SPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTN 443
Query: 438 XX-NVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNTFM-------QKNGKLSKTRDI 489
+ E+ +I L+ + G +TSKL GM RD+ SNT M Q G D+
Sbjct: 444 KSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDL 503
Query: 490 SVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAY 549
+V VLT +WP Q + ++ P + + Y HSGR L +H+ + ++
Sbjct: 504 TVRVLTTGYWPTQSATPKCNI--PPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNA 561
Query: 550 QF----------------------RNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTN 587
F H L + F I MLF E TF+EI + T+
Sbjct: 562 TFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETD 621
Query: 588 LPQQEVRKNLISMSVA-PKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNT 646
+P++E+ + L S++ P ++L K P K I N +F++N FT+ +VK+ V
Sbjct: 622 IPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTV---A 678
Query: 647 RPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSIPL-FEMSP 705
+D R +K+ D R I AA+ RIMK +K+ H+ L +V + F SP
Sbjct: 679 AKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSP 738
Query: 706 SLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ K +E L+ EY+ R ++ +Y Y+
Sbjct: 739 VVIKKRIEGLIEREYLARTPEDRKVYTYV 767
>7298217 [D] KOG2166 Cullins
Length = 773
Score = 208 bits (530), Expect = 2e-53
Identities = 193/756 (25%), Positives = 333/756 (43%), Gaps = 66/756 (8%)
Query: 30 WAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHF-GKVRTSF 88
WA L+N I +I + LSFE+LY Y +VL K+G +L+ L +S+H KVR
Sbjct: 32 WASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLYYGLREVVSEHLEHKVRADV 91
Query: 89 DGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRLFLKEVVE 148
+ L LNQ W + + I D+ +YMD VY ++ +V +LG LF +VV
Sbjct: 92 LEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVR 151
Query: 149 H--VSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKEGMSSVFLMEFEPFL 206
+ + L+ L+ + + R A +KNA ++L +L + +V+ +FE
Sbjct: 152 YSEIQKALREKLLGMVMEERHGEA--INHLAIKNACSMLITLGINS--RTVYEEDFEKPF 207
Query: 207 LDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAER 266
L + A+YK +AE + + ++ D+DT ++ + E
Sbjct: 208 LAQSAAFYKFESQNFLAENNA---GVYIKKVEARITEESSRAALYLDKDTEPRIVRVVEE 264
Query: 267 VLVTDN---IQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKDK--NVIFDQLSQFIVKEI 321
L+ + I E+ V ++ + K + L+ + S K++ VI D +S ++ ++
Sbjct: 265 ELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQG 324
Query: 322 TSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQIK 381
+ + ++Q L+ LKD++ + H + I+ F +
Sbjct: 325 RMLVKE--EENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLNN 382
Query: 382 IFPEFLSLYFDNYLKSEPSAM-----DSNIRKCVQFFKLFKDKDAFEIIY-XXXXXXXXX 435
PE+LSL+ D+ LK M +S + K + F+ +KD FE Y
Sbjct: 383 KSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLL 442
Query: 436 XXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNTFMQK------NGKLSKTR-D 488
+ E+ +I L+ + G +TSKL GM +D+ SNT M + N LS +
Sbjct: 443 NKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNFVNNNNLSLGGVE 502
Query: 489 ISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIA 548
++V +LT FWP Q + N + +P + + ++N Y HSGR L + T I
Sbjct: 503 LTVRILTTGFWPTQTATPNCN--IPAAPREAFDIFKNFYLNKHSGRQLTLQPQMGTAYIN 560
Query: 549 YQF--------------------------RNSYHELSMPMFSGIIFMLFKEHESLTFDEI 582
F H L + + + +LF + LT+D+I
Sbjct: 561 AVFYGRKAVESEKDKDAPSSSSSGCGVPTTTRKHILQVSTYQMCVLLLFNNRDVLTYDDI 620
Query: 583 VELTNLPQQEVRKNLISMSVA-PKTKILQKSPPGKS--ISNTDMFSINQGFTAPQRKVKV 639
+ T++P++E+ + L S+S+ P ++L ++ K+ I TD F +N F + +VK+
Sbjct: 621 HQETDIPERELVRALQSLSMGKPAQRLLVRNSKTKTKDIEPTDEFYVNDAFNSKFHRVKI 680
Query: 640 LMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSI- 698
V TR V+ + R I AA+ RIMK ++L H+ L V +
Sbjct: 681 QTVAAKGESEPERKETRGKVD----EDRKHEIEAAIVRIMKARKRLAHNLLVSDVTSQLK 736
Query: 699 PLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
F SP K +E L+ EY+QR ++ +Y+YL
Sbjct: 737 SRFLPSPVFIKKRIEGLIEREYLQRSPEDRKVYNYL 772
>Hs13270467 [D] KOG2167 Cullins
Length = 717
Score = 187 bits (474), Expect = 6e-47
Identities = 163/727 (22%), Positives = 315/727 (42%), Gaps = 47/727 (6%)
Query: 27 DEQWAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHFGKVRT 86
DE W L+ ++ I + + + E+LY V L K L+++L + DH
Sbjct: 18 DETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIH 77
Query: 87 SF--DGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENK-PDVMSLGSRLFL 143
F D + L +++ W+ + I +F+++D Y + + P + +G LF
Sbjct: 78 QFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFR 137
Query: 144 KEVVEHVSGTLKSSLVDEINQARESAAQYSGFD--ILKNAIAVLNSLELKEGMSSVFLME 201
++ +++ +D I E D +L++ +++L+ L++ +
Sbjct: 138 AHIISDQK--VQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQD-------S 188
Query: 202 FEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLH 261
FE L+ T Y +L+ E++ + I + DQ T L
Sbjct: 189 FEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLIT---YLDQTTQKSLI 245
Query: 262 NIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKDK-NVIFDQLSQFIVKE 320
E+ L+ +++ I + +++ ++ LS L + S + V+ Q ++I
Sbjct: 246 ATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAF 305
Query: 321 ITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQI 380
++I I+ +QEL+ KDK + + EAF ++
Sbjct: 306 GSTIVINPEKDKTM------VQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 359
Query: 381 KIFP-EFLSLYFDNYLKS-EPSAMDSNIRKCVQ----FFKLFKDKDAFEIIYXXXXXXXX 434
P E ++ Y D+ L++ A D + K + F+ KD FE Y
Sbjct: 360 PNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRL 419
Query: 435 XXX-XXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNTFM------QKNGKLSKTR 487
+V E+ ++ L+ + G ++TSKL GM +D+ S M +N +
Sbjct: 420 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNI 479
Query: 488 DISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEI 547
+++VN+LT +WP + +V +P ++ ++ Y HSGR L+W L +
Sbjct: 480 ELTVNILTMGYWPTY---VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVL 536
Query: 548 AYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTK 607
+F+ EL + +F ++ ++F E E + +EI + T + E+R+ L S++ K +
Sbjct: 537 KAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACG-KAR 595
Query: 608 ILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSR 667
+L K+P GK I + D F N F K K+ + +N ++S +++ R
Sbjct: 596 VLAKNPKGKDIEDGDKFICNDDF-----KHKLFRIKINQIQMKETVEEQASTTERVFQDR 650
Query: 668 LSVINAAVTRIMKQDRKLYHSELQDKVALSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDN 727
I+AA+ RIMK + L H+ L +V + F + P+ K +E L++ +Y++RD +N
Sbjct: 651 QYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLK-FPVKPADLKKRIESLIDRDYMERDKEN 709
Query: 728 TTMYHYL 734
Y+Y+
Sbjct: 710 PNQYNYI 716
>CE27593 [D] KOG2166 Cullins
Length = 777
Score = 180 bits (456), Expect = 8e-45
Identities = 182/770 (23%), Positives = 328/770 (41%), Gaps = 76/770 (9%)
Query: 26 LDEQ-----WAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDH 80
+DEQ W +L+ I +I + LSFE+LY Y +VL K+G +L+ L + DH
Sbjct: 22 IDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDH 81
Query: 81 FGKVRTS-FDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKP-DVMSLG 138
VR + + L + + W V + I D+ +YMD +Y + N V +LG
Sbjct: 82 MASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLG 141
Query: 139 SRLFLKEVVEH--VSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKEGMSS 196
+ E++ + ++ +L++ I R+S + +KNA +L SL + +
Sbjct: 142 LDAYRTEILRQNGIGDRIRDALLELIKLDRKS--NQINWHGIKNACDMLISLGIDS--RT 197
Query: 197 VFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDT 256
V+ EFE LL T YY+++ ++ ++ + + + + D+ T
Sbjct: 198 VYEDEFERPLLKETSDYYRDVCKNWLSGDNDACF--YLAQVEIAMHDEASRASRYLDKMT 255
Query: 257 ILKLHNIAERVLVTDNIQEIAIY---NVAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQL 313
K+ + + V+V ++IQ I V ++ K + L+R+ I D +
Sbjct: 256 EAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGG 315
Query: 314 SQFIVKEITSIEIDTXXXXXXXXX-----XXWIQELIKLKDKYQELGSHLNSAQAAGFKC 368
+ ++K ++ +T ++ EL++LKD + L + +
Sbjct: 316 LKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNR 375
Query: 369 INEAFGKAFSQIKIFPEFLSLYFDNYLKS-----EPSAMDSNIRKCVQFFKLFKDKDAFE 423
F + + PEF++LY D+ L+S + MD+ + + F+ ++KD FE
Sbjct: 376 FQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFE 435
Query: 424 II---YXXXXXXXXXXXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRD------LHSSN 474
Y +V E+ L+ L+ + G +T KL M RD L +S
Sbjct: 436 KYFKQYLAKRLLLDKSCSDDV--EKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSF 493
Query: 475 TFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGR 534
++ + DIS+ VLT WP + V++P + + Y + H+GR
Sbjct: 494 RDWREAQPTKMSIDISLRVLTAGVWP---TVQCNPVVLPQELSVAYEMFTQYYTEKHTGR 550
Query: 535 LLEWNYHLSTVEIAYQF--------------------------RNSYHE-LSMPMFSGII 567
L N L ++ F R H+ L + II
Sbjct: 551 KLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMII 610
Query: 568 FMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKT-KILQKSPPGK-SISNTDMFS 625
+ F H ++ ++++ +P++E+++NL S+++ + +IL + GK +I +D F+
Sbjct: 611 LLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDEFA 670
Query: 626 INQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKL 685
+N F + +VKV MV TR VE D R + AA+ RIMK +KL
Sbjct: 671 VNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVE----DDRKLEVEAAIVRIMKARKKL 726
Query: 686 YHSELQDKVALSI-PLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
H+ L +V + F SP + K +E L+ EY+ RD + Y Y+
Sbjct: 727 NHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYI 776
>At1g43140 [D] KOG2166 Cullins
Length = 711
Score = 164 bits (414), Expect = 6e-40
Identities = 180/750 (24%), Positives = 297/750 (39%), Gaps = 87/750 (11%)
Query: 26 LDEQWAILQNGIDKI--FDGKVTELSFE-----KLYTTVYGLVLTKNGPQLHERLS---R 75
L+E W++++ G+ K+ ++E F+ LYT +Y + L + + L R
Sbjct: 7 LEEGWSVMKTGVAKLQRILEDLSEPPFDPGQYINLYTIIYDMCLQQPPNDYSQELYNKYR 66
Query: 76 QLSDHFGKVRTSFDGITRAEALNLLNQV---WEKQKVYLSQISDVFIYMDSVYSKRENKP 132
+ DH+ K T + +L ++ W K+ + +S Y+D Y R P
Sbjct: 67 GVVDHYNK-ETVLPSMRERHGEYMLRELVKRWANHKILVRWLSRFCFYLDRFYVARRGLP 125
Query: 133 DVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKE 192
+ +G F V + + K L+ I++ RE + ++KN I V +
Sbjct: 126 TLNDVGFTSFHDLVYQEIQSEAKDVLLALIHKEREG--EQIDRTLVKNVIDVYCGNGV-- 181
Query: 193 GMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFE 252
G ++ +FE FLL T +YY S+ E D+ C E
Sbjct: 182 GQMVIYEEDFESFLLQDTASYYSRKASRW---SQEDSCPDYMLKAEE--------CLKLE 230
Query: 253 DQDTILKLHNIAERVLVTDNIQEIAIYNVAK------------IVNSDKNDVLSRLLAIS 300
+ LH+ E LV + +Q + VAK ++ DK LSR+ +
Sbjct: 231 KERVTNYLHSTTEPKLV-EKVQNELLVVVAKQLIENEHSGCLALLRDDKMGDLSRMYRLY 289
Query: 301 SS-QKDKNVIFDQLSQFIVKEITSI---EIDTXXXXXXXXXXXWIQELIKLKDKYQELGS 356
+ I D Q + E ++ D +++ I+L DKY
Sbjct: 290 RLIPQGLEPIADLFKQHVTAEGNALIKQAADAATNQDASASQVLVRKEIELHDKYMVYVD 349
Query: 357 HLNSAQAAGFKCINEAFGKAFSQIKIF----PEFLSLYFDNYLKSE-------PSAMDSN 405
+ K + EAF + F + E L+ Y DN LK+ A +
Sbjct: 350 ECFQKHSLFHKLLKEAF-EVFCNKTVAGASSAEILATYCDNILKTRGGSEKLSDEATEIT 408
Query: 406 IRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXXXXNVLREQELIFLLQEDVGTSYTSKLRG 465
+ K V DKD F Y +++E I L +E + T++
Sbjct: 409 LEKVVNLLVYISDKDLFAEFYRKKQARRLLFDRSGIMKEVTDITLARE-LQTNFVD---- 463
Query: 466 MLRDLHSSNTFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYEN 525
++ N D +V VLT FWP S D+ +P ++
Sbjct: 464 ----------YLSANMTTKLGIDFTVTVLTTGFWP---SYKTTDLNLPTEMVNCVEAFKV 510
Query: 526 RYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVEL 585
Y + R L W Y L T I +F EL + + + +LF E L++ EI E
Sbjct: 511 FYGTKTNSRRLSWIYSLGTCHILGKFEKKTMELVVSTYQAAVLLLFNNAERLSYTEISEQ 570
Query: 586 TNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMN 645
NL +++ + L S+S K KIL K P ++IS TD F N FT RK++V + M+
Sbjct: 571 LNLSHEDLVRLLHSLSCL-KYKILIKEPMSRTISKTDTFEFNSKFTDKMRKIRVPLPPMD 629
Query: 646 TRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSI-PLFEMS 704
R D V+K R I+AA+ RIMK + L H +L + + +F+
Sbjct: 630 ERKKVVED-----VDK----DRRYAIDAALVRIMKSRKVLAHQQLVSECVEHLSKMFKPD 680
Query: 705 PSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ K +E L+N +Y++RD +N + Y+
Sbjct: 681 IKMIKKRIEDLINRDYLERDTENANTFKYV 710
>Hs11140811 [D] KOG2167 Cullins
Length = 659
Score = 162 bits (411), Expect = 1e-39
Identities = 150/685 (21%), Positives = 295/685 (42%), Gaps = 47/685 (6%)
Query: 69 LHERLSRQLSDHFGKVRTSF--DGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYS 126
L+++L + DH F D + L +N W+ + I +F+++D Y
Sbjct: 2 LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYV 61
Query: 127 KRENK-PDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQA--RESAAQYSGFDILKNAIA 183
+ + P + +G LF ++ ++S +D I RE + + +L++ +
Sbjct: 62 LQNSTLPSIWDMGLELFRTHIIS--DKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLG 119
Query: 184 VLNSLELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXX 243
+L+ L+ V+ FE L+ T Y +L+ E++ + +
Sbjct: 120 MLSDLQ-------VYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGD 172
Query: 244 XKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQ 303
I + D T L E+ L+ +++ I + +++ ++ L+++ + S
Sbjct: 173 RVIT---YLDHSTQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLFSRV 229
Query: 304 KD-KNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQ 362
+ + + S++I T+I I+ +Q+L+ KDK +
Sbjct: 230 RGGQQALLQHWSEYIKTFGTAIVINPEKDKDM------VQDLLDFKDKVDHVIEVCFQKN 283
Query: 363 AAGFKCINEAFGKAFSQIKIFP-EFLSLYFDNYLKS-----EPSAMDSNIRKCVQFFKLF 416
+ E+F ++ P E ++ + D+ L++ ++ + K + F+
Sbjct: 284 ERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFI 343
Query: 417 KDKDAFEIIYXXXXXXXXXXX-XXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNT 475
KD FE Y +V E+ ++ L+ + G ++TSKL GM +D+ S
Sbjct: 344 HGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKD 403
Query: 476 FM------QKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAK 529
M +N S D++VN+LT +WP +V + ++ ++ Y
Sbjct: 404 IMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTP---MEVHLTPEMIKLQEVFKAFYLG 460
Query: 530 THSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLP 589
HSGR L+W L + +F+ E + +F ++ ++F E + +F+EI T +
Sbjct: 461 KHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIE 520
Query: 590 QQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPN 649
E+R+ L S++ K ++L KSP GK + + D F N F ++K+ + M
Sbjct: 521 DSELRRTLQSLACG-KARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQM----K 575
Query: 650 ATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSIPLFEMSPSLFK 709
T + S+ E+ D R I+AA+ RIMK + L H+ L ++ + F + P K
Sbjct: 576 ETVEEQVSTTERVFQD-RQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLK-FPVKPGDLK 633
Query: 710 MSLEYLLNNEYIQRDFDNTTMYHYL 734
+E L++ +Y++RD DN YHY+
Sbjct: 634 KRIESLIDRDYMERDKDNPNQYHYV 658
>At4g02570 [D] KOG2166 Cullins
Length = 676
Score = 155 bits (391), Expect = 3e-37
Identities = 177/755 (23%), Positives = 306/755 (40%), Gaps = 123/755 (16%)
Query: 21 RKTEGLDEQWAILQNGIDK---IFDGKVTELSFEK-----LYTTVYGLVLTKNGPQLHER 72
RKT L++ W +Q GI K I +G + E +F+ LYTT+Y + T+ P +
Sbjct: 3 RKTIDLEQGWDYMQTGITKLKRILEG-LNEPAFDSEQYMMLYTTIYNMC-TQKPPHDY-- 58
Query: 73 LSRQLSDHFGKVRTSFDGITRAEALN------LLNQV---WEKQKVYLSQISDVFIYMDS 123
S+QL D + + + T AL +L ++ W KV + +S F Y+D
Sbjct: 59 -SQQLYDKYREAFEEYINSTVLPALREKHDEFMLRELFKRWSNHKVMVRWLSRFFYYLDR 117
Query: 124 VYSKRENKPDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDILKNAIA 183
+ R + P + +G F V + G ++I++A +LKN +
Sbjct: 118 YFIARRSLPPLNEVGLTCFRDLVDKEREG-------EQIDRA-----------LLKNVLD 159
Query: 184 VLNSLELK---EGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXX 240
+ + LK E ++ EP L++ + H L+ + K+
Sbjct: 160 IYSEECLKKERERVAHYLHSSSEPKLVEKVQ------HELLVVFASQLLEKEHSG----- 208
Query: 241 XXXXKICCNIFEDQ--DTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLA 298
C + D D + +++ + ++L + + N K V +
Sbjct: 209 ------CRALLRDDKVDDLSRMYRLYHKIL----------RGLEPVANIFKQHVTA---- 248
Query: 299 ISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHL 358
+ N + Q ++ + I+++I+L DKY +
Sbjct: 249 ------EGNALVQQAEDTATNQVAN--------TASVQEQVLIRKVIELHDKYMVYVTEC 294
Query: 359 NSAQAAGFKCINEAFGKAFSQIKIF----PEFLSLYFDNYLKSEPS------AMDSNIRK 408
K + EAF + F + E L+ + DN LK S A++ + K
Sbjct: 295 FQNHTLFHKALKEAF-EIFCNKTVAGSSSAELLATFCDNILKKGGSEKLSDEAIEDTLEK 353
Query: 409 CVQFFKLFKDKDAFEIIYXXXXXXXXXXX-XXNVLREQELIFLLQEDVGTSYTSKLRGML 467
V+ DKD F Y N E+ ++ L++ G +TSK+ GM+
Sbjct: 354 VVKLLAYISDKDLFAEFYRKKLARRLLFDRSANDDHERSILTKLKQQCGGQFTSKMEGMV 413
Query: 468 RDL-------HSSNTFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIR 520
DL +S ++ N + D++V VLT FWP S + D+ +P
Sbjct: 414 TDLTLARENQNSFEDYLGSNPAANPGIDLTVTVLTTGFWP---SYKSFDINLPSEMIKCV 470
Query: 521 NEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFD 580
++ Y R L W Y L T I +F EL + + + +LF + L++
Sbjct: 471 EVFKGFYETKTKHRKLTWIYSLGTCHINGKFDQKAIELIVSTYQAAVLLLFNTTDKLSYT 530
Query: 581 EIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVL 640
EI+ NL +++ + L S+S A K KIL K P K++S D F N FT R++K+
Sbjct: 531 EILAQLNLSHEDLVRLLHSLSCA-KYKILLKEPNTKTVSQNDAFEFNSKFTDRMRRIKIP 589
Query: 641 MVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSIP- 699
+ ++ R D V+K R I+AA+ RIMK + L H +L + +
Sbjct: 590 LPPVDERKKVVED-----VDK----DRRYAIDAAIVRIMKSRKVLGHQQLVSECVEQLSR 640
Query: 700 LFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+F+ K +E L+ +Y++RD +N M+ YL
Sbjct: 641 MFKPDIKAIKKRMEDLITRDYLERDKENPNMFRYL 675
>At1g02980 [D] KOG2166 Cullins
Length = 648
Score = 149 bits (377), Expect = 1e-35
Identities = 119/414 (28%), Positives = 187/414 (44%), Gaps = 34/414 (8%)
Query: 341 IQELIKLKDKYQELGSHLNSAQAAGFKCINEAF----GKAFSQIKIFPEFLSLYFDNYLK 396
I++LI L DK+ + K + EAF K + + E L+ Y DN LK
Sbjct: 248 IRQLIDLHDKFMVYVDECFQKHSLFHKALKEAFEVFCNKTVAGVSS-AEILATYCDNILK 306
Query: 397 S-------EPSAMDSNIRKCVQFFKLFKDKDAF-EIIYXXXXXXXXXXXXXNVLREQELI 448
+ E ++ + K V+ DKD F E N E+ L+
Sbjct: 307 TGGGIEKLENEDLELTLEKVVKLLVYISDKDLFAEFFRKKQARRLLFDRNGNDYHERSLL 366
Query: 449 FLLQEDVGTSYTSKLRGMLRDL-----HSSN--TFMQKNGKLSKTRDISVNVLTNMFWPL 501
+E +G +TSK+ GML D+ H +N F+ N D +V VLT FWP
Sbjct: 367 TKFKELLGAQFTSKMEGMLTDMTLAKEHQTNFVEFLSVNKTKKLGMDFTVTVLTTGFWP- 425
Query: 502 QGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMP 561
S D+ +P ++ Y + R L W Y L T ++A +F E+ +
Sbjct: 426 --SYKTTDLNLPIEMVNCVEAFKAYYGTKTNSRRLSWIYSLGTCQLAGKFDKKTIEIVVT 483
Query: 562 MFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNT 621
+ + +LF E L++ EI+E NL +++ + L S+S K KIL K P ++ISNT
Sbjct: 484 TYQAAVLLLFNNTERLSYTEILEQLNLGHEDLARLLHSLSCL-KYKILIKEPMSRNISNT 542
Query: 622 DMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQ 681
D F N FT R+++V + M+ R D V+K R I+AA+ RIMK
Sbjct: 543 DTFEFNSKFTDKMRRIRVPLPPMDERKKIVED-----VDK----DRRYAIDAALVRIMKS 593
Query: 682 DRKLYHSELQDKVALSI-PLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ L H +L + + +F+ + K +E L++ +Y++RD DN + YL
Sbjct: 594 RKVLGHQQLVSECVEHLSKMFKPDIKMIKKRIEDLISRDYLERDTDNPNTFKYL 647
>CE24979 [D] KOG2167 Cullins
Length = 833
Score = 147 bits (372), Expect = 4e-35
Identities = 159/753 (21%), Positives = 326/753 (43%), Gaps = 75/753 (9%)
Query: 23 TEG-LDEQWAILQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHF 81
T+G + WA+L + + I + + T + E L++ V + L++RL +
Sbjct: 114 TDGSVGRDWAVLSDNVFAILEDRKTVTTLEGLFSKVRSVCDKNQSKVLYDRLVAIVVQFA 173
Query: 82 GKVRTSFDGITRA--------EALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKPD 133
++ S + + + + L Q+W+ V ++ I ++F+++D + + +
Sbjct: 174 KSLKESLNAVEQVPLAEDNCEQYLEKFGQIWQAYPVKINLIRNIFLHLDRI-ALGATDTE 232
Query: 134 VMSLGS---RLFLKEVVEHVSGTLKSS-LVDEINQARESAAQYSGFDI-LKNAIAVLNSL 188
++ L ++F K ++ K++ L + + A + Q D L++ + +L ++
Sbjct: 233 ILPLWECFMQIFQKTFFPNIFKEFKATKLFNALYMAMQKIMQRYPVDSPLRSLVDMLQTV 292
Query: 189 ELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICC 248
+ E EF FL+ +Y N + I + + D+
Sbjct: 293 HVSE--------EFAKFLISQLREHYNN---ERIDKVPKMNCNDYMEYCEDQINRYSQLV 341
Query: 249 NIFEDQDTILK-LHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSS-QKDK 306
+ D+ + LK + L+ I EI ++ +++SD + R+ + +
Sbjct: 342 KVNFDEPSALKDVQATVTNCLIQQAIPEILTHDFDDLIDSDNISDIGRMFNLCRQCVGGE 401
Query: 307 NVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQEL--GSHLNSAQAA 364
+ + Q S+++ K + + EL+ K K + GS ++
Sbjct: 402 DEVRTQFSKYLKKRGEKL-------IATCPDEDLVSELLAFKKKVDFIMTGSFKSANDPV 454
Query: 365 GFK-CINEAFGKAFS-QIKIFPEFLSLYFDNYLKS------EPSAMDSNIRKCVQFFKLF 416
+ C+++AF + Q+ E +S +F L S + + +D + + + F+
Sbjct: 455 KMRQCLSDAFESFVNKQVDRSAELISKHFHTLLHSSNKNVSDDTTLDQMVDEAIVLFRYL 514
Query: 417 KDKDAFEIIYXXXXXXXXXXXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNT- 475
+ KD FE Y L + +++ G+++T KL GM +D+ +S
Sbjct: 515 RGKDVFEAYYKRGLAKRLF------LERSASVDAGKDECGSAFTYKLEGMFKDMDASENY 568
Query: 476 ---FMQKNGKLSKTR-DISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTH 531
F Q ++K + + + V+T +WP + ++ +P +Y++ Y H
Sbjct: 569 GRLFNQYLEHMNKEKANFTARVITPEYWPTYDT---YEINIPKEMRDTLTDYQDFYRVQH 625
Query: 532 SGRLLEWNYHLSTVEIAYQFR-NSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQ 590
R ++W++ L++ I+ FR EL M+ +I +LF + E+ T EIVE T + +
Sbjct: 626 GNRNVKWHHGLASAVISASFRPGCKKELIATMYQTVILLLFNKCETWTVAEIVEHTKILE 685
Query: 591 QEVRKNLIS-MSVAPKTKILQKSPPGKS------ISN--TDMFSINQGFTAPQRKVKVLM 641
EV KN+++ + K K+LQ+ G S + N + F +N FT + +V++
Sbjct: 686 IEVVKNVLALLGGRDKPKVLQRVEGGGSEKKEGTVENLKNEKFVVNSKFTEKRCRVRIAQ 745
Query: 642 VLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSIPLF 701
V + T T + V++++ R I+AAV RIMK ++L H L ++ + F
Sbjct: 746 VNIKTAVEETKE-----VKEEVNSDRQYKIDAAVVRIMKARKQLNHQTLMTELLQQL-RF 799
Query: 702 EMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+S + K LE L+ EYI RD + + Y+Y+
Sbjct: 800 PVSTADIKKRLESLIEREYISRDPEEASSYNYV 832
>7304097 [D] KOG2167 Cullins
Length = 773
Score = 135 bits (341), Expect = 2e-31
Identities = 159/719 (22%), Positives = 295/719 (40%), Gaps = 79/719 (10%)
Query: 33 LQNGIDKIFDGKVTELSFEKLYTTVYGLVLTKNGPQLHERLSRQLSDHFG---KVRTSFD 89
L+ + I K + S E+LY V + K QL+ +L H K++
Sbjct: 116 LEEAVIAIQLSKPIKYSLEELYQAVVNMCSHKMDAQLYAKLKELTEQHVKRNIKLKELTG 175
Query: 90 G-ITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENKP-DVMSLGSRLFLKEVV 147
G + + L +N W + I +F+YMD Y + + + +G LF
Sbjct: 176 GSMDKLILLEKINHWWLSFCQQMIMIRSIFLYMDRTYVLQNSTVHSIWDMGLDLFRIHFA 235
Query: 148 EHVSGTLKSSLVDEINQARESAAQYSGFD--ILKNAIAVLNSLELKEGMSSVFLMEFEPF 205
++ ++ VD + E Q S D +LK+ + +L L+ ++ FE
Sbjct: 236 QN--SVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCDLQ-------IYTSSFEEK 286
Query: 206 LLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAE 265
LD+T YK ++ + E ++ + D T L E
Sbjct: 287 FLDATNQLYK---AESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDSSTKHPLIYNVE 343
Query: 266 RVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKD-KNVIFDQLSQFIVKEITSI 324
+ L+ +++ I + ++ ++ L+ L + S K+ + + + FI K+ +I
Sbjct: 344 KELLAEHLTSILQKGLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCGNFNGFIKKKGRTI 403
Query: 325 EIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQIKIFP 384
ID +Q+L+ KDK + + EAF +Q P
Sbjct: 404 VIDPEKDKSM------VQDLLDFKDKMDVIVRTCFEHNEKFTNSLREAFEFFINQRANKP 457
Query: 385 -EFLSLYFDNYLKS-EPSAMDSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXXXXNVL 442
E ++ Y D L+S D + K + K D + + +V
Sbjct: 458 AELIAKYVDMKLRSGNKGTTDEELEKTLD-----KIMDLAKRLLVGKSA--------SVD 504
Query: 443 REQELIFLLQEDVGTSYTSKLRGMLRDLHSSN--TFMQKNGKLSKTRDIS-----VNVLT 495
E+ ++ L+++ G +TSKL GM +D+ S + LS RD+ V++LT
Sbjct: 505 SEKSMLSKLKQECGGGFTSKLEGMFKDMELSRDINIAFRGHALSNNRDVHNLDLCVSILT 564
Query: 496 NMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSY 555
+WP +V +P F + + Y + HSGR L+W L + QF
Sbjct: 565 MGYWPTYAPT---EVTMPPQFINPQQIFNKFYLEKHSGRKLQWQPTLGNCMLRAQF---- 617
Query: 556 HELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPG 615
+ L+++EI+ T + E+R+ L S++ + +++ K+P G
Sbjct: 618 -----------------DAPVLSYEEILAATLIEDGELRRTLQSLACG-RARVITKTPKG 659
Query: 616 KSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAV 675
+ I + D F N FT ++K+ + M TN+ +++ E+++ R I+AA+
Sbjct: 660 REILDGDQFDFNNEFTNKLFRIKINQIQMKE----TNEEQKAT-EERVFQDRQYQIDAAI 714
Query: 676 TRIMKQDRKLYHSELQDKVALSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
RIMK + L H+ L ++ + F + P+ K +E L++ +Y++RD DN Y+Y+
Sbjct: 715 VRIMKMRKTLSHNLLITELFNQLT-FPVKPADLKKRIESLIDRDYMERDKDNQNQYNYV 772
>7304137 [D] KOG2166 Cullins
Length = 774
Score = 132 bits (333), Expect = 1e-30
Identities = 162/785 (20%), Positives = 314/785 (39%), Gaps = 83/785 (10%)
Query: 16 NRRYSRKTEGLDEQWAILQNGIDKIFDGK--VTELSFEKLYTTVYGLVLTKN-------- 65
N + ++K LD+ W+ L GI ++F+ + +T + + YT VY + +
Sbjct: 6 NSQTTQKLVNLDDIWSELVEGIMQVFEHEKSLTRSQYMRFYTHVYDYCTSVSAAPSGRSS 65
Query: 66 ---------GPQLHERLSRQLSDHFGKVRTSFDGITRAEAL-NLLNQVWEKQKVYLSQIS 115
G +L++RL + L + ++ T F I+ E L + + W+ + + +
Sbjct: 66 GKTGGAQLVGKKLYDRLEQFLKSYLSELLTKFKAISGEEVLLSRYTKQWKSYQFSSTVLD 125
Query: 116 DVFIYMDSVYSKRENKPDVMSLGS--RLFLKEVVEHVSGTLKSSLVDEINQARESAAQYS 173
+ Y++ + KRE + + RL L H+ L + + ++ E Q
Sbjct: 126 GICNYLNRNWVKRECEEGQKGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGK 185
Query: 174 GFD--ILKNAIAVLNSLELKEGMS-------SVFLMEFEPFLLDSTEAYYKNLHSQLIAE 224
+ ++++ I L E + SV+ FE + T A+Y+ ++
Sbjct: 186 LINRSLVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLST 245
Query: 225 QDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKI 284
T + F ++ + LH VL + +E+ I KI
Sbjct: 246 NTVTEYLKHVENRLEEETQR---VRGFNSKNGLSYLHETTADVLKS-TCEEVLIEKHLKI 301
Query: 285 --------VNSDKNDVLSRLLA-ISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXX 335
+N+D+ND L R+ + ++ S K+ + L I+ + T
Sbjct: 302 FHTEFQNLLNADRNDDLKRMYSLVALSSKNLTDLKSILENHILHQGTEAIAKCCTTDAAN 361
Query: 336 XXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQIKIF--------PEFL 387
++Q ++ + KY L + +++A GK + + PE L
Sbjct: 362 DPKTYVQTILDVHKKYNALVLTAFNNDNGFVAALDKACGKFINSNVVTIANSASKSPELL 421
Query: 388 SLYFDNYLKS-----EPSAMDSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXX-XXXNV 441
+ Y D LK E ++ N+ + + FK +DKD F+ Y +
Sbjct: 422 AKYCDLLLKKSSKNPEDKELEDNLNQVMVVFKYIEDKDVFQKYYSKMLAKRLVNHTSASD 481
Query: 442 LREQELIFLLQEDVGTSYTSKLRGMLRDLHSS---NTFMQK---NGKLSKTRDISVNVLT 495
E +I L++ G YT KL+ M +D+ S N++ ++ L+ D + VL+
Sbjct: 482 DAEAMMISKLKQTCGYEYTVKLQRMFQDIGVSKDLNSYFKQYLAEKNLTMEIDFGIEVLS 541
Query: 496 NMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFR--- 552
+ WP Q ++ + ++P ++ YA HSGR L W Y + E+
Sbjct: 542 SGSWPFQ---LSNNFLLPSELERSVRQFNEFYAARHSGRKLNWLYQMCKGELIMNVNRNN 598
Query: 553 NSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLIS-MSVAPKTKILQK 611
+S + L F + + F + S T ++ + T Q+ NLI + + K K+L
Sbjct: 599 SSTYTLQASTFQMSVLLQFNDQLSFTVQQLQDNTQTQQE----NLIQVLQILLKAKVLTS 654
Query: 612 SPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDST-RSSVEKKLLDSRLSV 670
S S++ + + +R++ + +P T + +V K + + R +
Sbjct: 655 SDNENSLTPESTVELFLDYKNKKRRINI------NQPLKTELKVEQETVHKHIEEDRKLL 708
Query: 671 INAAVTRIMKQDRKLYHSELQDKVALSIPL-FEMSPSLFKMSLEYLLNNEYIQRDFDNTT 729
I AA+ RIMK ++L H+ L +V + F+ + K ++ L+ EY++R +
Sbjct: 709 IQAAIVRIMKMRKRLNHTNLISEVLNQLSTRFKPKVPVIKKCIDILIEKEYLERMEGHKD 768
Query: 730 MYHYL 734
Y YL
Sbjct: 769 TYSYL 773
>At5g46210 [D] KOG2167 Cullins
Length = 617
Score = 130 bits (327), Expect = 7e-30
Identities = 138/641 (21%), Positives = 267/641 (41%), Gaps = 48/641 (7%)
Query: 114 ISDVFIYMDSVYS-KRENKPDVMSLGSRLFLKEV--VEHVSGTLKSSLVDEINQARESAA 170
I + + +D Y + N + +G +LF K + V L+ I +E A
Sbjct: 4 IRSIALTLDRKYVIQNPNVRSLWEMGLQLFRKHLSLAPEVEQRTVKGLLSMIE--KERLA 61
Query: 171 QYSGFDILKNAIAVLNSLELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRW 230
+ +L + + + +L +++ FE L+ T +Y + + + D
Sbjct: 62 EAVNRTLLSHLLKMFTAL-------GIYMESFEKPFLEGTSEFYAAEGMKYMQQSDVP-- 112
Query: 231 KDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKN 290
++ C ++ D T L ER L+ +I + +++ +
Sbjct: 113 -EYLKHVEGRLHEENERCILYIDAVTRKPLITTVERQLLERHILVVLEKGFTTLMDGRRT 171
Query: 291 DVLSRLLAISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDK 350
+ L R+ + S + LS ++ K I +D +Q L+ K
Sbjct: 172 EDLQRMQTLFSRVNALESLRQALSSYVRKTGQKIVMDEEKDKDM------VQSLLDFKAS 225
Query: 351 YQELGSHLNSAQAAGFKCINEAFGKAFSQIKIFP-EFLSLYFDNYLKS-----EPSAMDS 404
+ + I ++F + + P E ++ + D L++ ++S
Sbjct: 226 LDIIWEESFYKNESFGNTIKDSFEHLINLRQNRPAELIAKFLDEKLRAGNKGTSEEELES 285
Query: 405 NIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXX-XXNVLREQELIFLLQEDVGTSYTSKL 463
+ K + F+ + KD FE Y ++ E+ +I L+ + G+ +T+KL
Sbjct: 286 VLEKVLVLFRFIQGKDVFEAFYKKDLAKRLLLGKSASIDAEKSMISKLKTECGSQFTNKL 345
Query: 464 RGMLRDLHSSNTFMQKNGKLSKTR-------DISVNVLTNMFWPLQGSDMNRDVIVPDSF 516
GM +D+ S + + S+ R ++SV+VLT +WP DV +P
Sbjct: 346 EGMFKDIELSKEINESFKQSSQARTKLPSGIEMSVHVLTTGYWPTYPP---MDVKLPHEL 402
Query: 517 AAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMF--SGIIFMLFKEH 574
++ ++ Y +SGR L W L + F EL++ +F S I F
Sbjct: 403 NVYQDIFKEFYLSKYSGRRLMWQNSLGHCVLKADFSKGKKELAVSLFQVSQIFFPPPPLL 462
Query: 575 ES-LTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAP 633
S L+ +I + T++ +E+R+ L S++ K ++LQK+P G+ + + D F N F AP
Sbjct: 463 SSFLSSRDIKDSTSIEDKELRRTLQSLACG-KVRVLQKNPKGRDVEDGDEFEFNDEFAAP 521
Query: 634 QRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDK 693
++KV + M +T +++ R I+AA+ RIMK + L H+ L +
Sbjct: 522 LYRIKVNAIQMKETVEENTSTT-----ERVFQDRQYQIDAAIVRIMKTRKVLSHTLLITE 576
Query: 694 VALSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ + F + P+ K +E L++ EY++R+ N +Y+YL
Sbjct: 577 LFQQLK-FPIKPADLKKRIESLIDREYLEREKSNPQIYNYL 616
>Hs4503161 [D] KOG2166 Cullins
Length = 752
Score = 130 bits (326), Expect = 9e-30
Identities = 154/767 (20%), Positives = 308/767 (40%), Gaps = 68/767 (8%)
Query: 15 SNRRYSRKTEGLDEQWAILQNGIDKIFDGK-VTELSFEKLYTTVYGLVLTKN---GPQLH 70
S + K GLD+ W L+ GI +++ + + + + +LYT VY + + G +L+
Sbjct: 6 SQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQFVGLELY 65
Query: 71 ERLSRQLSDHFGKVRTSFDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKREN 130
+RL L ++ + + + L Q WE + ++ + Y++ + +RE
Sbjct: 66 KRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRREC 125
Query: 131 KPDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQARESAA------QYSGFDILKNAIAV 184
R + E+ T + L +N+ +A + +G I I+
Sbjct: 126 DE------GRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISG 179
Query: 185 LNSLELKEGMS-----------SVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDF 233
+ ++ G++ +V+ FE L TE +Y ++ + + T ++
Sbjct: 180 VVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVT---EY 236
Query: 234 XXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVL 293
+ ++ + T +L E+VL+ ++ EI ++++DKN+ L
Sbjct: 237 MKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHL-EIFHTEFQNLLDADKNEDL 295
Query: 294 SRLLAISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQE 353
R+ + S +D +L + + I+ ++Q ++ + KY
Sbjct: 296 GRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNA 355
Query: 354 LGSHLNSAQAAGFKCINEAFGKAFSQIKIF---------PEFLSLYFDNYLKS-----EP 399
L + A +++A G+ + + PE L+ Y D+ LK E
Sbjct: 356 LVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEE 415
Query: 400 SAMDSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXX-XXNVLREQELIFLLQEDVGTS 458
+ ++ + + + FK +DKD F+ Y + E +I L++ G
Sbjct: 416 AELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFE 475
Query: 459 YTSKLRGMLRDLHSSNTFMQKNGK-LSKTR----DISVNVLTNMFWPLQGSDMNRDVIVP 513
YTSKL+ M +D+ S ++ K L+ + D S+ VL++ WP Q S +P
Sbjct: 476 YTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCT---FALP 532
Query: 514 DSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKE 573
+ YA HSGR L W Y LS E+ + + L F I + +
Sbjct: 533 SELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNT 592
Query: 574 HESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTD-----MFSINQ 628
++ T ++ + T + + + L + K+K+L ++ + + +
Sbjct: 593 EDAYTVQQLTDSTQIKMDILAQVL---QILLKSKLLVLEDENANVDEVELKPDTLIKLYL 649
Query: 629 GFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHS 688
G+ + +V + V M T ++T ++E + R +I AA+ RIMK + L H
Sbjct: 650 GYKNKKLRVNI-NVPMKTEQKQEQETTHKNIE----EDRKLLIQAAIVRIMKMRKVLKHQ 704
Query: 689 ELQDKVALSI-PLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+L +V + F+ + K ++ L+ EY++R Y YL
Sbjct: 705 QLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYL 751
>Hs19482174 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component
Length = 745
Score = 127 bits (318), Expect = 8e-29
Identities = 161/760 (21%), Positives = 308/760 (40%), Gaps = 78/760 (10%)
Query: 27 DEQWAILQNGIDKIFDGKVTE-LSFEKLYTTVYGLVLTKNGPQLHERLSRQ----LSDHF 81
DE W L I + + E ++ ++ +Y L + P L ERL + L +H
Sbjct: 11 DETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEP-LGERLYTETKIFLENH- 68
Query: 82 GKVRTSFDGITRAE--ALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRE---------- 129
VR + +E L + ++ WE+ + ++ Y+++ + K+
Sbjct: 69 --VRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYG 126
Query: 130 ------NKP--DVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDILKNA 181
N+P ++ L ++ K +VE + L L+ EI R G D +
Sbjct: 127 YGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDR------GGEDPNQKV 180
Query: 182 I-AVLNSLELKEGMSSVFLMEF------EPFLLDSTEAYYKNLHSQLIAEQDETRWKDFX 234
I V+NS E F ++F PFL ++ E YYK S L+ E + +++ +
Sbjct: 181 IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGE-YYKQEASNLLQESNCSQYME-- 237
Query: 235 XXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLS 294
+I C + + K+ + ++ +V D++Q + I KND+ +
Sbjct: 238 -KVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHAECHNIIRQEKKNDMAN 296
Query: 295 RLLAISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQEL 354
+ + + + +L I E T +++ ++++ K+ +L
Sbjct: 297 MYVLLRAVSTGLPHMIQELQNHIHDEGLRA---TSNLTQENMPTLFVESVLEVHGKFVQL 353
Query: 355 GSHLNSAQAAGFKCINEAFGKAFS-----QIKIFPEFLSLYFDNYLKSEPSAMDSN---- 405
+ + + +++A + + PE L+ Y DN LK M N
Sbjct: 354 INTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVED 413
Query: 406 -IRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXXXXNVLREQE-LIFLLQEDVGTSYTSKL 463
+ + FK DKD F+ Y + +E +I L++ G +TSKL
Sbjct: 414 RLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKL 473
Query: 464 RGMLRDLHSSNTFMQKNGKLSKTRDISVN--------VLTNMFWPLQGSDMNRDVIVPDS 515
M D+ S K K +D ++ VL WPL + + I P
Sbjct: 474 HRMYTDMSVSADLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAI-PQE 532
Query: 516 FAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHE 575
+E Y++ SGR L W ++L T E+ + + + + + + F E
Sbjct: 533 LEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSE 592
Query: 576 SLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQR 635
++++ E+ + T + ++E+ K + S+ K++ + I FS+N F++ +
Sbjct: 593 TVSYKELQDSTQMNEKELTKTIKSLL---DVKMINHDSEKEDIDAESSFSLNMNFSSKRT 649
Query: 636 KVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSEL-QDKV 694
K K+ + P + TRS+V+ + R + AA+ RIMK + L H+ L Q+ +
Sbjct: 650 KFKITTSMQKDTPQEM-EQTRSAVD----EDRKMYLQAAIVRIMKARKVLRHNALIQEVI 704
Query: 695 ALSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ S F S S+ K +E L++ +YI+R + Y Y+
Sbjct: 705 SQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYV 744
>SPAC17G6.12 [D] KOG2166 Cullins
Length = 767
Score = 124 bits (311), Expect = 5e-28
Identities = 152/766 (19%), Positives = 307/766 (39%), Gaps = 70/766 (9%)
Query: 21 RKTEGLDEQWAILQNGIDKIF---DGKVTELSFEKLYTTVYGLVLTKN------------ 65
+K + L+ W L+ G+ +IF D +T + +LYT ++ +
Sbjct: 15 KKYDSLNGTWDFLKTGVSQIFERLDEGMTITKYMELYTAIHNYCADASKTITVDNFNDQT 74
Query: 66 ----GPQLHERLSRQLSDHFGKVRTSFDGITR-AEALNLLNQVWEKQKVYLSQISDVFIY 120
G L+ L L ++ ++R T E L + W + I+ +F Y
Sbjct: 75 ANVLGEALYNNLVLYLEEYLARLRKECISQTNHEEQLAAYAKYWTRFTTSARFINHLFGY 134
Query: 121 MDSVYSKRENK------PDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQAR-ESAAQYS 173
++ + K +N+ D+ +L + V H+ +L +L+ + R
Sbjct: 135 LNRYWVKLKNRFTETLVYDIYTLCLVSWHHHVFSHIRDSLLQNLLYMFTKKRLYEPTDMK 194
Query: 174 GFDILKNAIAVLN--SLELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWK 231
++ ++I L+ ++ + S + FE +++T+ +Y S+ +A T
Sbjct: 195 YVEVCVDSITSLSFDKTDMTKPNLSSYKTFFETNFIENTKNFYAKESSEYLASHSIT--- 251
Query: 232 DFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKND 291
D+ + ++ + T+ L E VL+ + +E+ + A++++ + ++
Sbjct: 252 DYLKKAEIRLAEEEELVRLYLHESTLKPLLEATEDVLIAQH-EEVLHNDFARMLDQNCSE 310
Query: 292 VLSRLLAISSSQKDKNVIFDQLSQFIVKE-----ITSIEIDTXXXXXXXXXXXWIQELIK 346
+ R+ + S + Q + VK + I + +++ L+
Sbjct: 311 DIIRMYRLMSRTPNGLQPLRQTFEEFVKRSGFAAVAKI-VPQVGGEADVDPKEYMEMLLS 369
Query: 347 LKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQIKIF-------PEFLSLYFDNYLKSEP 399
+EL + K ++ AF + ++ + PE L+ Y D+ L+
Sbjct: 370 TYKASKELVNTAFHGDTDFTKSLDTAFRELVNRNVVCQRSSSRSPELLAKYADSILRKSN 429
Query: 400 SAMD-SNIRKCVQ----FFKLFKDKDAFEIIYXXXXXXXXXXXXXNVL-REQELIFLLQE 453
+D ++ C+ F+ +DKD F+ Y N E ++ L+E
Sbjct: 430 KNVDIDDVEDCLSSIIIIFRYVEDKDVFQNFYTKLLAKRLVNGTSNSQDAESSMLSKLKE 489
Query: 454 DVGTSYTSKLRGMLRDLHSSNTFMQKNGKLSKTR----DISVNVLTNMFWPLQGSDMNRD 509
G YTSKL+ M +D+ S + +L ++R D S VL FWPL +++N
Sbjct: 490 VCGFEYTSKLQRMFQDISLSQEITEAFWQLPQSRAGNIDFSALVLGTSFWPLSPNNVNFH 549
Query: 510 VIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFR---NSYHELSMPMFSGI 566
+ P+ + ++N Y H+GR L W +HLS EI + N + + +
Sbjct: 550 L--PEELVPLYEGFQNYYYSCHNGRKLSWLFHLSKGEIKARINPQTNVTYVFQVSTYQMG 607
Query: 567 IFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSI 626
+ +L+ +S T++E+ ++T L + L ++ K K+L K + I
Sbjct: 608 VLLLYNHRDSYTYEELAKITGLSTDFLTGIL---NIFLKAKVLLLGDNDKLGDPNSTYKI 664
Query: 627 NQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLY 686
N+ F ++K + V +N + K + + R ++ +A+ RIMK R L
Sbjct: 665 NENF-----RMKKIRVQLNLPIRSEQKQESLETHKTIEEDRKLLLQSAIVRIMKARRTLK 719
Query: 687 HSELQDKVALSI-PLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMY 731
H L + I F S K ++ L+ EY++R + +Y
Sbjct: 720 HVVLVKETIDQIKSRFTPKVSDIKQCIDMLIEKEYLERQGRDEYIY 765
>SPAC3A11.08 [D] KOG2167 Cullins
Length = 734
Score = 121 bits (304), Expect = 3e-27
Identities = 158/762 (20%), Positives = 298/762 (38%), Gaps = 70/762 (9%)
Query: 8 PSVKPIISNRRYSRKTEGLDEQWAI-----LQNGIDKIFDGKVTELSFEKLYTTVYGLVL 62
P K I+ RK+ E + + L + + G + +++LY+ V L
Sbjct: 3 PEAKRIVVKGFDPRKSRQRQETYYVTMIDRLNMALQVVMAGLGLKTGYQELYSGVENLTR 62
Query: 63 TKNGPQLHERLSRQLSDHFGKVRTSFDGITRAE-------ALNLLNQVWEKQKVYLSQIS 115
+ L +S ++ S + + E A ++ W K + +
Sbjct: 63 ADQASRCFNILQHHMSSGIQLLKDSAESFIQLEGTETDTNACTVVVGCWNKWLERVEIVQ 122
Query: 116 DVFIYMDSVY-SKRENKPDVMSLGSRLFLKEV--VEHVSGTLKSSLVDEINQARESAAQY 172
++F YMD + S + P + L LF +++ V+++ +SL+ S +
Sbjct: 123 NIFYYMDKTFLSHHPDYPTIEELSLSLFREKLMAVKNIQIPFLNSLLQSFENLHSSKSTD 182
Query: 173 SGFDILKNAIAVLNSLELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKD 232
+ L++A+ +L+ E+ SSVF+ P L +Y SQ I E + +
Sbjct: 183 HAY--LQDAMLMLHRTEM---YSSVFV----PMYLVMLSRFYDTESSQKIQELPLEEYLE 233
Query: 233 FXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDV 292
+ +I D+ +I +R L+T ++ + +++ +
Sbjct: 234 YAMSSLEREDAYVEKFDIVRDKKSI---RETVQRCLITSHLDTLT-KGISQFIEKRDAHS 289
Query: 293 LSRLLAISSSQKDKNVIFDQLSQFIV----KEITSIEIDTXXXXXXXXXXXWIQELIKLK 348
L A+ + + S +V K + D ++Q ++
Sbjct: 290 CKLLYALLQFNHETEYLIQPWSDCLVDVGFKLVNDESKDDTLVQELLSFHKFLQVVVDES 349
Query: 349 DKYQELGSHLNSAQAAGFKC-INEAFGKAFSQIKIFPEFLSLYFDNYLKSEPSAMDSNIR 407
+ E L+ A F+ IN A G SQ + ++ Y D L+ A
Sbjct: 350 FLHDET---LSYAMRKAFETFINGAKG---SQREAPARLIAKYIDYLLRVGEQASGGKPL 403
Query: 408 KCV-----QFFKLFKDKDAFEIIYXXXXXXXXXXX-XXNVLREQELIFLLQEDVGTSYTS 461
K V F+ KD FE Y + E L+ +L++ G+ +T
Sbjct: 404 KEVFSEILDLFRYIASKDIFEAYYKLDIAKRLLLNKSASAQNELMLLDMLKKTCGSQFTH 463
Query: 462 KLRGMLRDLHSS----NTFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFA 517
L GM RD++ S ++F + RD+ VNVL+ +WP S + +PD
Sbjct: 464 SLEGMFRDVNISKEFTSSFRHSKAAHNLHRDLYVNVLSQAYWP---SYPESHIRLPDDMQ 520
Query: 518 AIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKE---H 574
+ +E Y G+ + W L + +F ELS+ +F + + F
Sbjct: 521 QDLDCFEKFYLSKQVGKKISWYASLGHCIVKARFPLGNKELSISLFQACVLLQFNNCLGG 580
Query: 575 ESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQ 634
E +++ ++ + T L ++ + L S+S A + + L P K S MF +N+ FT
Sbjct: 581 EGISYQDLKKSTELSDIDLTRTLQSLSCA-RIRPLVMVPKSKKPSPDTMFYVNEKFTDKL 639
Query: 635 RKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKV 694
+VK+ + + +D V+++++ R + A++ R+MKQ K+ H +L V
Sbjct: 640 YRVKINQIYLKEERQENSD-----VQEQVVRDRQFELQASIVRVMKQKEKMKHDDLVQYV 694
Query: 695 A-----LSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMY 731
IPL S K ++E LL EY++R+ ++ Y
Sbjct: 695 INNVKDRGIPLV----SDVKTAIEKLLEKEYLEREDNDIYTY 732
>7302125 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component
Length = 703
Score = 116 bits (291), Expect = 1e-25
Identities = 140/675 (20%), Positives = 284/675 (41%), Gaps = 58/675 (8%)
Query: 94 AEALNLLNQVW---EKQKVYLSQISDVFIYMDSVYSKRENKPDVMSLGSRLFLKEVVEHV 150
++ + L+Q++ +Q + +I+D + ++ S + ++ LG ++ ++E++
Sbjct: 52 SQGIKYLHQLYIYLNQQHIKKQKITDTESFYGNLSSDAAEQMEIGELGLDIWRLYMIEYL 111
Query: 151 SGTLKSSLVDEI--NQARESAAQYSGFDILKNAIAVLNSLE--LKEGMSSVFLMEFEPFL 206
S L +++ I ++A + I+ I ++ K G ++ FE +
Sbjct: 112 SSELVRHILEGIAADRASNGTLDHHRVQIINGVIHSFVEVQDYKKTGSLKLYQELFEGPM 171
Query: 207 LDSTEAYY-----KNLHSQLIAE--QDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILK 259
L+++ AYY K LH ++E Q+ R ++ F ++ K
Sbjct: 172 LEASGAYYTDEANKLLHRCSVSEYMQEVIRILEYESRRAQK----------FLHVSSLPK 221
Query: 260 LHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQLSQFIVK 319
L E + D + I ++V+ ++ L + + D + +L +
Sbjct: 222 LRKECEEKFINDRLGFI-YSECREMVSEERRQDLRNMYVVLKPIPDN--LKSELITTFLD 278
Query: 320 EITSIEIDTXXXXXXXXXX-XWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFS 378
I S + T +++ ++K+ KYQEL + + + +++A +
Sbjct: 279 HIKSEGLQTVSALKGENIHIAFVENMLKVHHKYQELIADVFENDSLFLSALDKACASVIN 338
Query: 379 QIKI------FPEFLSLYFDNYLKSEPSA---MDSNIRKCVQFFKLFKDKDAFEIIYXXX 429
+ E+++ Y D LK + +D + + FK +DKD ++ Y
Sbjct: 339 RRPTERQPCRSAEYVAKYCDTLLKKSKTCEAEIDQKLTNNITIFKYIEDKDVYQKFYSRL 398
Query: 430 XXXXXXXXXXNVLREQE-LIFLLQEDVGTSYTSKLRGMLRDLHSS-------NTFMQ-KN 480
+ +E +I L++ G +T+KL M D+ S NT ++ N
Sbjct: 399 LAKRLIHEQSQSMDAEEGMINRLKQACGYEFTNKLHRMFTDISVSVDLNNKFNTHLKDSN 458
Query: 481 GKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNY 540
L ++++ VL WPL GS VP F +E+ Y K SGR L W +
Sbjct: 459 VDLDAGINLAIKVLQAGAWPL-GSTQVIPFAVPQEFEKSIKMFEDYYHKLFSGRKLTWLH 517
Query: 541 HLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISM 600
H+ E+ + ++M + I +LF+ +SL+ EI L + +K+ M
Sbjct: 518 HMCHGELKLSHLKKSYIVTMQTYQMAIILLFETCDSLSCREIQNTLQLNDETFQKH---M 574
Query: 601 SVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVE 660
++K+L S ++++ +N +T + K K+ L P + T +SV+
Sbjct: 575 QPIIESKLLNAS--SENLAGETRIELNLDYTNKRTKFKISSALQKETPQEV-EHTINSVD 631
Query: 661 KKLLDSRLSVINAAVTRIMKQDRKLYHSEL-QDKVALSIPLFEMSPSLFKMSLEYLLNNE 719
+ R + AA+ RIMK + L H+ L Q+ ++LS F + ++ K +E L++ +
Sbjct: 632 ----EDRKLFLQAAIVRIMKARKVLKHNALIQEVLSLSKVSFTPNIAMIKKCVESLIDKQ 687
Query: 720 YIQRDFDNTTMYHYL 734
YI+R ++ Y Y+
Sbjct: 688 YIERTANSGDEYSYM 702
>YDL132w [D] KOG2166 Cullins
Length = 815
Score = 111 bits (277), Expect = 5e-24
Identities = 168/832 (20%), Positives = 313/832 (37%), Gaps = 143/832 (17%)
Query: 22 KTEGLDEQWAILQNGIDKIFDGKVTELSFEK-------------LYTTVYGLVLTKN--- 65
+++ L+ W ++ GI++I + + S K +YT +Y + K+
Sbjct: 7 RSDDLEATWNFIEPGINQILGNEKNQASTSKRVYKILSPTMYMEVYTAIYNYCVNKSRSS 66
Query: 66 ----------------GPQLHERLSRQLSDHFGKVRTSFDGITRAEALNLLNQVWEKQKV 109
G +++E+L L ++ +F L + W++ +
Sbjct: 67 GHFSTDSRTGQSTILVGSEIYEKLKNYLKNYI----LNFKQSNSETFLQFYVKRWKRFTI 122
Query: 110 YLSQISDVFIYMDSVYSKRENKP------DVMSLGSRLFLKEVVEHVSGTLKSSLVDEIN 163
++ F YM+ + ++E DV +L + + + + L + L+D++
Sbjct: 123 GAIFLNHAFDYMNRYWVQKERSDGKRHIFDVNTLCLMTWKEVMFDPSKDVLINELLDQVT 182
Query: 164 QARESAA-QYSGFDI-LKNAIAV-LNSLELKEGMSSVFLMEFEPFLLDSTEAYYKNLHSQ 220
RE Q S +K+ +A+ ++ +LK+ +V++ FE L T+ YY +
Sbjct: 183 LGREGQIIQRSNISTAIKSLVALGIDPQDLKKLNLNVYIQVFEKPFLKKTQEYYTQYTND 242
Query: 221 LIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYN 280
+ + T ++ + I+ D T L +VL+TD+I+++
Sbjct: 243 YLEKHSVT---EYIFEAHEIIKREEKAMTIYWDDHTKKPLSMALNKVLITDHIEKLENEF 299
Query: 281 VAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQLSQF--IVKEITSIEIDTXXX------- 331
V + D + S I ++D +I S F VK+ EI +
Sbjct: 300 VVLLDARDIEKITSLYALI---RRDFTLIPRMASVFENYVKKTGENEISSLLAMHKHNIM 356
Query: 332 --------------XXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAF 377
+I++L+++ D + ++ + K ++ A G AF
Sbjct: 357 KNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSKIFNESFPDDIPLAKALDNACG-AF 415
Query: 378 SQIKIFP--------------EFLSLYFDNYLKSEPS---AMDSNIRKCVQFFKLFKDKD 420
I F E L+ Y D LK A D + + FK DKD
Sbjct: 416 ININEFALPAGSPKSATSKTSEMLAKYSDILLKKATKPEVASDMSDEDIITIFKYLTDKD 475
Query: 421 AFEIIYXXXXXXXXXXXXXNVLREQE-LIFLLQEDVGTSYTSKLRGMLRDLHSSNTF--- 476
AFE Y ++E +I LQ YT K+ M +D+ S
Sbjct: 476 AFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQAANSMEYTGKITKMFQDIRLSKILEDD 535
Query: 477 ----MQKNGKLSKTR--DISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKT 530
++ SK + D+ VL WP ++ + +P + + Y++
Sbjct: 536 FAVALKNEPDYSKAKYPDLQPFVLAENMWPFSYQEV--EFKLPKELVPSHEKLKESYSQK 593
Query: 531 HSGRLLEWNYHLSTVEIAYQFRNSYH---ELSMPMFSGIIFMLFKEHESLTFDEIVELTN 587
H+GR+L+W + L E+ ++ +F I +L+ + + LT + I E T+
Sbjct: 594 HNGRILKWLWPLCRGELKADIGKPGRMPFNFTVTLFQMAILLLYNDADVLTLENIQEGTS 653
Query: 588 LPQQEVRKNLISMSVAPKTKILQKSPPGKS--ISNTDMFSINQGFTAPQRKVKVLMVLMN 645
L Q + ++ K K++Q+ PPG + F ++ R K L +N
Sbjct: 654 LTIQHIAAAMVPFI---KFKLIQQVPPGLDALVKPETQFKLS-------RPYKALKTNIN 703
Query: 646 TRPNATNDSTRS----------------------SVEKKLLDSRLSVINAAVTRIMKQDR 683
ND +S +EK+L R + A + RIMK R
Sbjct: 704 FASGVKNDILQSLSGGGHDNHGNKLGNKRLTEDERIEKELNTERQIFLEACIVRIMKAKR 763
Query: 684 KLYHSELQDK-VALSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
L H+ L ++ +A S F S+ K +++ L+ Y+QR D+ Y YL
Sbjct: 764 NLPHTTLVNECIAQSHQRFNAKVSMVKRAIDSLIQKGYLQRG-DDGESYAYL 814
>7301740 [O] KOG2285 E3 ubiquitin ligase Cullin 1 component
Length = 852
Score = 99.8 bits (247), Expect = 1e-20
Identities = 88/375 (23%), Positives = 166/375 (43%), Gaps = 29/375 (7%)
Query: 384 PEFLSLYFDNYLKSEPSA-------MDSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXX 436
PE L+ Y D L+ P + +D+ +R + K +KD F +
Sbjct: 482 PELLANYCDMLLRRTPLSKRLTSEQIDARLRDVLLVLKYVNNKDVFMRYHKVHLTRRLIL 541
Query: 437 XXXNVLREQELIFLLQEDVG--TSYTSKLRGMLRDLHSSNTF-MQKNGKLSKTRDISVNV 493
++E I +VG Y ++L M +D+ S Q +S+ I++ +
Sbjct: 542 GTSADSEKEEDIVEWLREVGMPADYVNRLARMFQDIKVSEDLNTQFRTSISRHDAINIKI 601
Query: 494 LTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRN 553
L W ++ V +P + E Y K HSGR L+W +H+S I +
Sbjct: 602 LNAGAWARCSERVS--VSLPIELEDYIPDVEEFYKKKHSGRKLQWYHHMSNGTITFVNNF 659
Query: 554 SYHELSMPMFSGIIFMLF--KEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTK--IL 609
++L + F + + ++H+ ++++ + T LP E+R+ L S+ PK K IL
Sbjct: 660 GRYDLDVTTFQMAVLFAWNQRQHDKISYENLRLATELPDPELRRTLWSLVAFPKIKKQIL 719
Query: 610 QKSPPG----KSISNTDMFSINQGFT-----APQRKVKVLMVLMNTRPNATNDSTRSSVE 660
P K + MF INQ F QR+ K+ ++ R + + ++
Sbjct: 720 LMEPAAISSPKDFAENTMFYINQEFAIVKNGKSQRRGKLNLI---GRLQLSTERSQQEDN 776
Query: 661 KKLLDSRLSVINAAVTRIMKQDRKLYHSELQ-DKVALSIPLFEMSPSLFKMSLEYLLNNE 719
+ ++ R+ A+ +IMK +++ ++ LQ + + + +F S + K LE+L+ N+
Sbjct: 777 QSIVQLRILRTQEAIIKIMKVRKRMNNAALQGELIDILKNMFLPSKKMIKEQLEWLIENK 836
Query: 720 YIQRDFDNTTMYHYL 734
Y++RD D+ M+ Y+
Sbjct: 837 YMRRDDDDINMFIYV 851
>Hs4503167 [O] KOG2285 E3 ubiquitin ligase Cullin 1 component
Length = 780
Score = 96.7 bits (239), Expect = 1e-19
Identities = 85/380 (22%), Positives = 168/380 (43%), Gaps = 34/380 (8%)
Query: 384 PEFLSLYFDNYLKSEPSA-------MDSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXX 436
PE L+ Y D L+ P + +++ +++ + K ++KD F +
Sbjct: 405 PELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLIL 464
Query: 437 --XXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNTF------MQKNGKLSKTRD 488
+ + E + +L + + Y +KL M +D+ S M KN KL+ D
Sbjct: 465 DISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPAD 524
Query: 489 -ISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEI 547
+++ +L W + V +P + E E Y K HSGR L W++ +S I
Sbjct: 525 SVNIKILNAGAWSRSSEKVF--VSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGII 582
Query: 548 AYQFRNSYHELSMPMFSGIIFMLFKE--HESLTFDEIVELTNLPQQEVRKNLISMSVAPK 605
++ ++L + F + + + E ++F+ + T LP E+R+ L S+ PK
Sbjct: 583 TFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPK 642
Query: 606 TK--ILQKSP---PGKSISNTDMFSINQGFT-----APQRKVKVLMVLMNTRPNATNDST 655
K + P K + +FS+NQ F+ Q++ K+ ++ R T +
Sbjct: 643 LKRQVFLYDPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLI---GRLQLTTERM 699
Query: 656 RSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQ-DKVALSIPLFEMSPSLFKMSLEY 714
R + ++ R+ A+ +IMK +K+ +++LQ + V + +F + K +E+
Sbjct: 700 REEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEW 759
Query: 715 LLNNEYIQRDFDNTTMYHYL 734
L+ ++YI+RD + + Y+
Sbjct: 760 LIEHKYIRRDESDINTFIYM 779
>CE11928 [D] KOG2166 Cullins
Length = 729
Score = 94.7 bits (234), Expect = 4e-19
Identities = 151/760 (19%), Positives = 295/760 (37%), Gaps = 85/760 (11%)
Query: 26 LDEQWAILQNGIDKIFDGK-VTELSFEKLYTTVYGLVLT-------KNGPQ-----LHER 72
++ W LQ+G++ ++ + +++ + LY VY + T N P+ L+++
Sbjct: 3 IEAVWGTLQDGLNLLYRREHMSKKYYMMLYDAVYNICTTTTLANSNNNSPEFASEFLYKQ 62
Query: 73 LSRQLSDHFGKVRTSFDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDS--VYSKREN 130
L + + +R + E L W+ K + +F Y++ V K E+
Sbjct: 63 LENYIRTYVIAIRDRISACSGDELLGKCTIEWDNFKFSTRICNCIFQYLNRNFVSKKVED 122
Query: 131 KPDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLEL 190
K + +L L K +D I + +L+ + +NS +
Sbjct: 123 KNGEIVEIYKLALDIWKAEFFDNFKVKTIDAILE----------LILLERCGSTINSTHI 172
Query: 191 KEGMS-----SVFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXK 245
+ ++ + FEP LD+T+ +YK Q + ET
Sbjct: 173 SSVVECLTELDIYKVSFEPQFLDATKLFYK----QEVLNSKET----------VIEYMIT 218
Query: 246 ICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIYNVAKIVNSD--------KNDVLSRLL 297
+ +F+++ + + L+ D+ + I I + K ++S+ K++ L+R+
Sbjct: 219 VENRLFQEEYRSRRYLGPSTNDLLIDSCESILISDRLKFLHSEFERLLEARKDEHLTRMY 278
Query: 298 A----ISSSQKDKNVIFDQLSQFIVKE-ITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQ 352
+ ++ +D V L + I+KE +++ +I +L+++ + Y
Sbjct: 279 SLCRRVTHGLEDLRVY---LEKRILKEGHETLQRLAKDSGLKTTPKEYITKLLEVHEIYF 335
Query: 353 ELGSHLNSAQAAGFKCINEA---FGKAFSQIKIFPE---------FLSLYFDNYLKSEPS 400
L + A + +++A F +A + + PE +L+ Y D LK
Sbjct: 336 NLINKAFDRNALFMQSLDKASKDFIEANAVTMLAPEKHRSTRSADYLARYCDQLLKKNSK 395
Query: 401 AMDSN-IRKCVQFFKLFKDKDAFEIIYXX-XXXXXXXXXXXNVLREQELIFLLQEDVGTS 458
D + K + K +KD F++ Y + E++ I L G
Sbjct: 396 VQDETALDKALTVLKYISEKDVFQLYYQNWFSERIINNSSASDDAEEKFITNLTATEGLE 455
Query: 459 YTSKLRGMLRDLHSSN--TFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSF 516
YT L M+ D S T K+ K K+ D +V + T WP S +I+P
Sbjct: 456 YTRNLVKMVEDAKISKDLTTEFKDIKTEKSIDFNVILQTTGAWP---SLDQIKIILPREL 512
Query: 517 AAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHES 576
+ I E++ Y +H+GR L W Y E+ + + + LF E +S
Sbjct: 513 STILKEFDTFYNASHNGRRLNWAYSQCRGEVNSKAFEKKYVFIVTASQLCTLYLFNEQDS 572
Query: 577 LTFDEIVELTNLPQQEVRKNLISMS-VAPKTKILQKSPPGKSISNTDMFSINQGFTAPQR 635
T ++I + + + + S++ V ++ K + S+N +
Sbjct: 573 FTIEQISKAIEMTAKSTSAIVGSLNPVIDPVLVVDKGNEKDGYPPDAVVSLNTKYA---- 628
Query: 636 KVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVA 695
KV + L AT D +V+ + R I A + RIMK + L H+ L +++
Sbjct: 629 NKKVRVDLTTAIKKATADRETDAVQNTVESDRKYEIKACIVRIMKTRKSLTHTLLINEII 688
Query: 696 LSI-PLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ F + + K+ +E L+ YI+R + +Y YL
Sbjct: 689 SQLKSRFTPNVQMIKICIEILIEQLYIRRSENEHNVYEYL 728
>CE29089 [D] KOG2166 Cullins
Length = 780
Score = 93.6 bits (231), Expect = 1e-18
Identities = 150/795 (18%), Positives = 305/795 (37%), Gaps = 90/795 (11%)
Query: 14 ISNRRYSRKTEGLDEQWAILQNGIDKIFDGK-VTELSFEKLYTTVY----GLVLTKN--- 65
++N R T + W LQ+G+D + + + + LYT+VY + L+ +
Sbjct: 1 MTNSEPRRMTCDSEVVWKKLQDGLDVAYRRENMAPKDYMTLYTSVYDYCTSITLSTSRRD 60
Query: 66 --------------------GPQLHERLSRQLSDHFGKVRTSFDGITRAEALNLLNQVWE 105
G ++++R+ + + V ++ + L WE
Sbjct: 61 GEDGRAESSTPARTAGADFVGHEMYQRVEEYVKAYVIAVCEKGAELSGEDLLKYYTTEWE 120
Query: 106 KQKVYLSQISDVFIYMDSVYSKRE------NKPDVMSLGSRLFLKEVVEHVSGTLKSSLV 159
++ + +F Y++ + +RE N V +L ++ + + + + +++
Sbjct: 121 NFRISSKVMDGIFAYLNRHWIRRELDEGHENIYMVYTLALVVWKRNLFNDLKDKVIDAML 180
Query: 160 DEINQARESAAQYSGFDILKNAIAVLNSLELKEGMS-----------SVFLMEFEPFLLD 208
+ I R + S + + + L L + + + +V+ FE L+
Sbjct: 181 ELIRSERTGSMINSRY--ISGVVECLVELGVDDSETDAKKDAETKKLAVYKEFFEVKFLE 238
Query: 209 STEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVL 268
+T +Y + ++ D+ C ++ + T L E VL
Sbjct: 239 ATRGFYTQEAANFLSNGGNVT--DYMIKVETRLNQEDDRCQLYLNSSTKTPLATCCESVL 296
Query: 269 VTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKDK-NVIFDQLSQFIVKEITSIEID 327
+++ + + + +V+ ++D LSR+ + + + + L I KE ++
Sbjct: 297 ISNQLDFLQRHFGGLLVDK-RDDDLSRMFKLCDRVPNGLDELRKSLENHIAKEGHQA-LE 354
Query: 328 TXXXXXXXXXXXWIQELIKLKDKYQELGSH--------LNSAQAAGFKCINE-AFGKAF- 377
+++ L+++ ++YQ L + + S A IN A K
Sbjct: 355 RVAMEAATDAKLYVKTLLEVHERYQSLVNRSFKNEPGFMQSLDKAATSFINNNAVTKRAP 414
Query: 378 --SQIKIFPEFLSLYFDNYLKS-----EPSAMDSNIRKCVQFFKLFKDKDAFEIIYXXXX 430
+Q+ E L+ Y D L+ + + ++ K + FK DKD F Y
Sbjct: 415 PQAQLTKSAELLARYCDQLLRKSSKMPDEAELEELQTKIMVVFKYIDDKDVFSKFYTKMF 474
Query: 431 XXXXXXX-XXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHSSNT----FMQKNGKL-- 483
+ E I L+ G YT++L M+ D S F +K +
Sbjct: 475 SKRLISELSASDEAEANFITKLKSMCGYEYTARLSKMVNDTQVSKDLTADFKEKKADMLG 534
Query: 484 SKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLS 543
K+ + +V VL++ WP + + +P + + Y + +GR L W Y S
Sbjct: 535 QKSVEFNVLVLSSGSWP---TFPTTPITLPQQLSKTIEIFGQFYNEKFNGRRLTWVYSQS 591
Query: 544 TVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQE---VRKNLISM 600
EI + + +LF E +S T ++I T + ++ + +LI
Sbjct: 592 RGEITSTAFPKKYVFTATTAQMCTMLLFNEQDSYTVEQIAAATKMDEKSAPAIVGSLIKN 651
Query: 601 SVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVE 660
V LQK + T S+N+ + +KV+V + + +A D+ +V+
Sbjct: 652 LVLKADTELQKED---EVPMTATVSLNKAYM--NKKVRVDLSKFTMKQDAVRDT--ENVQ 704
Query: 661 KKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSIP-LFEMSPSLFKMSLEYLLNNE 719
K + + R SVI+A + RIMK +++ H +L +V + F+ + K + L+ E
Sbjct: 705 KNVEEDRKSVISACIVRIMKTRKRVQHQQLMTEVITQLSGRFKPKVEMIKRCIGSLIEKE 764
Query: 720 YIQRDFDNTTMYHYL 734
Y+ R +Y YL
Sbjct: 765 YMLRTEGQKDLYEYL 779
>CE25691 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component
Length = 804
Score = 66.2 bits (160), Expect = 2e-10
Identities = 128/791 (16%), Positives = 299/791 (37%), Gaps = 111/791 (14%)
Query: 8 PSVKPIISNRRYSR---------KTEGLDEQWAILQNGIDKIFDGK-VTELSFEKLYTTV 57
P V+PI+ R R K D+ W L+ I I + + +T + + ++ V
Sbjct: 60 PVVEPILKKIRPPRPQVMYSLKPKVVEFDKVWVQLRPSIIDIINLRPITNVQWHHKFSDV 119
Query: 58 YGLVLTKNGPQLHERLSRQ----LSDHFGKVRTSFDGITRAEALNLLNQVWEKQKVYLSQ 113
Y + ++ P L ERL + + +H + R + L +++W
Sbjct: 120 YDICVSIPTP-LSERLYNEVKACIQEHVRQKRQDIVDVDPDLLLQEYHKMWRVFHEGAIF 178
Query: 114 ISDVFIYMDSVYSKRENK---------------PDVMSLGS---RLFLKEVVEHVSGTLK 155
I +F Y++ + K++ PDV +G ++ +++V+ + L
Sbjct: 179 IHRLFGYLNKQFVKQKRCTDLDNFAQYAAFLQIPDVKEIGCLALEIWKEDLVKTILPQLV 238
Query: 156 SSLVDEINQARESAAQYSGFDILKNAIA-VLNSL------------------ELKEGMSS 196
L+ I+ R+ F + N ++ V+NS + +E ++
Sbjct: 239 KLLLIAIDNDRKG-----NFPHIANEVSGVINSFVKMEETDFDVVPAEGARYKARESTTA 293
Query: 197 VFLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDT 256
+ FE LL TE YY L +++ + ++ ++ + + +
Sbjct: 294 FYQESFEKPLLTDTEQYYSALAQKMLTDLS---CSEYMEQVIVLLEQEEMRAKKYLHESS 350
Query: 257 ILKLHNIAERVLVTDNIQEIAIYNVAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQLSQF 316
+ K+ + ++V++ + ++ I N + D+ + + Q +V+ + ++
Sbjct: 351 VEKVITLCQKVMIKAHKDKLHAVCHDLITNEENKDLRNMYRLLKPIQAGLSVMVKEFEEY 410
Query: 317 IVKEITSIEIDTXXXXXXXXXXXWIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKA 376
+ K+ +E +++ ++++ +K+ ++ + + +++A
Sbjct: 411 VKKK--GLEA-VSRLTGENVPQQFVENVLRVYNKFNDMKTAVFMDDGEFSSGLDKALQGV 467
Query: 377 FSQ------IKIFPEFLSLYFDNYLKSEPSAM-----DSNIRKCVQFFKLFKDKDAFEII 425
+ + E L+ Y D LK + ++ + + F+ +DKD F+
Sbjct: 468 VNSKEPGQSVPKASERLARYTDGLLKKSTKGLSETDLEAKLDSAIVIFRYIEDKDIFQKF 527
Query: 426 YXXXXXXXXXXXXXNVLREQELIF-LLQEDVGTSYTSKLRGMLRDLHSSNTFMQKNGKLS 484
Y + +EL+ L++ G +TS L++ N + +
Sbjct: 528 YSKMLANRLIASTSISMDAEELMINKLKQACGYEFTSSW-----PLNAPQLSTNSNNQTA 582
Query: 485 KTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLST 544
+ D++ L + P + E+E Y H+GR L W +++S
Sbjct: 583 Q--DVANFHLPRILQP------------------VIQEFEKFYTGKHNGRKLTWLFNMSQ 622
Query: 545 VEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAP 604
++ + + + M ++ + F+ +++ +I E + + K + ++
Sbjct: 623 GDVRLTYLDKQYVAQMYVYQMAALLCFERRDAILVKDIGEEIGVSGDYLLKTIRTI---- 678
Query: 605 KTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLL 664
+ + ++++ + +N T+ + K + L + N + + +V +
Sbjct: 679 -LDVTLLTCDDQNLTADSLVRLNMSMTSKRMKFR----LQAPQVNKAVEKEQEAVANTVS 733
Query: 665 DSRLSVINAAVTRIMKQDRKLYHSELQDKVA-LSIPLFEMSPSLFKMSLEYLLNNEYIQR 723
R + A+ RIMK + L H+ L ++ + F K S+E L+ YIQR
Sbjct: 734 QDRKYYMECAIVRIMKTRKVLKHNALVTEIMDQTKGRFSPDVPFIKKSIEDLIEKMYIQR 793
Query: 724 DFDNTTMYHYL 734
D Y YL
Sbjct: 794 T-DQNDEYQYL 803
>CE24730 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component
Length = 728
Score = 63.9 bits (154), Expect = 8e-10
Identities = 122/768 (15%), Positives = 291/768 (37%), Gaps = 102/768 (13%)
Query: 22 KTEGLDEQWAILQNGIDKIFDGK-VTELSFEKLYTTVYGLVLTKNGPQLHERLSRQ---- 76
K D+ W L+ I I + + +T + + ++ VY + ++ P L ERL +
Sbjct: 7 KVVEFDKVWVQLRPSIIDIINLRPITNVQWHHKFSDVYDICVSIPTP-LSERLYNEVKAC 65
Query: 77 LSDHFGKVRTSFDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENK----- 131
+ +H + R + L +++W I +F Y++ + K++
Sbjct: 66 IQEHVRQKRQDIVDVDPDLLLQEYHKMWRVFHEGAIFIHRLFGYLNKQFVKQKRCTDLDN 125
Query: 132 ----------PDVMSLGS---RLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDIL 178
PDV +G ++ +++V+ + L L+ I+ R+ F +
Sbjct: 126 FAQYAAFLQIPDVKEIGCLALEIWKEDLVKTILPQLVKLLLIAIDNDRKG-----NFPHI 180
Query: 179 KNAIA-VLNSL------------------ELKEGMSSVFLMEFEPFLLDSTEAYYKNLHS 219
N ++ V+NS + +E ++ + FE LL TE YY L
Sbjct: 181 ANEVSGVINSFVKMEETDFDVVPAEGARYKARESTTAFYQESFEKPLLTDTEQYYSALAQ 240
Query: 220 QLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIY 279
+++ + ++ ++ + + ++ K+ + ++V++ + ++
Sbjct: 241 KMLTDLS---CSEYMEQVIVLLEQEEMRAKKYLHESSVEKVITLCQKVMIKAHKDKLHAV 297
Query: 280 NVAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXX 339
I N + D+ + + Q +V+ + +++ K+ +E
Sbjct: 298 CHDLITNEENKDLRNMYRLLKPIQAGLSVMVKEFEEYVKKK--GLEA-VSRLTGENVPQQ 354
Query: 340 WIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQ------IKIFPEFLSLYFDN 393
+++ ++++ +K+ ++ + + +++A + + E L+ Y D
Sbjct: 355 FVENVLRVYNKFNDMKTAVFMDDGEFSSGLDKALQGVVNSKEPGQSVPKASERLARYTDG 414
Query: 394 YLKSEPSAM-----DSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXXXXNVLREQELI 448
LK + ++ + + F+ +DKD F+ Y + +EL+
Sbjct: 415 LLKKSTKGLSETDLEAKLDSAIVIFRYIEDKDIFQKFYSKMLANRLIASTSISMDAEELM 474
Query: 449 F-LLQEDVGTSYTSKLRGMLRDLHSSNTFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMN 507
L++ G +TS L++ N + ++ D++ L + P
Sbjct: 475 INKLKQACGYEFTSSW-----PLNAPQLSTNSNNQTAQ--DVANFHLPRILQP------- 520
Query: 508 RDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGII 567
+ E+E Y H+GR L W +++S ++ + + + M ++
Sbjct: 521 -----------VIQEFEKFYTGKHNGRKLTWLFNMSQGDVRLTYLDKQYVAQMYVYQMAA 569
Query: 568 FMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSIN 627
+ F+ +++ +I E + + K + ++ + + ++++ + +N
Sbjct: 570 LLCFERRDAILVKDIGEEIGVSGDYLLKTIRTI-----LDVTLLTCDDQNLTADSLVRLN 624
Query: 628 QGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYH 687
T+ + K + L + N + + +V + R + A+ RIMK + L H
Sbjct: 625 MSMTSKRMKFR----LQAPQVNKAVEKEQEAVANTVSQDRKYYMECAIVRIMKTRKVLKH 680
Query: 688 SELQDKVA-LSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ L ++ + F K S+E L+ YIQR D Y YL
Sbjct: 681 NALVTEIMDQTKGRFSPDVPFIKKSIEDLIEKMYIQRT-DQNDEYQYL 727
>CE16729 [O] KOG2284 E3 ubiquitin ligase Cullin 2 component
Length = 745
Score = 63.9 bits (154), Expect = 8e-10
Identities = 122/768 (15%), Positives = 291/768 (37%), Gaps = 102/768 (13%)
Query: 22 KTEGLDEQWAILQNGIDKIFDGK-VTELSFEKLYTTVYGLVLTKNGPQLHERLSRQ---- 76
K D+ W L+ I I + + +T + + ++ VY + ++ P L ERL +
Sbjct: 24 KVVEFDKVWVQLRPSIIDIINLRPITNVQWHHKFSDVYDICVSIPTP-LSERLYNEVKAC 82
Query: 77 LSDHFGKVRTSFDGITRAEALNLLNQVWEKQKVYLSQISDVFIYMDSVYSKRENK----- 131
+ +H + R + L +++W I +F Y++ + K++
Sbjct: 83 IQEHVRQKRQDIVDVDPDLLLQEYHKMWRVFHEGAIFIHRLFGYLNKQFVKQKRCTDLDN 142
Query: 132 ----------PDVMSLGS---RLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDIL 178
PDV +G ++ +++V+ + L L+ I+ R+ F +
Sbjct: 143 FAQYAAFLQIPDVKEIGCLALEIWKEDLVKTILPQLVKLLLIAIDNDRKG-----NFPHI 197
Query: 179 KNAIA-VLNSL------------------ELKEGMSSVFLMEFEPFLLDSTEAYYKNLHS 219
N ++ V+NS + +E ++ + FE LL TE YY L
Sbjct: 198 ANEVSGVINSFVKMEETDFDVVPAEGARYKARESTTAFYQESFEKPLLTDTEQYYSALAQ 257
Query: 220 QLIAEQDETRWKDFXXXXXXXXXXXKICCNIFEDQDTILKLHNIAERVLVTDNIQEIAIY 279
+++ + ++ ++ + + ++ K+ + ++V++ + ++
Sbjct: 258 KMLTDLS---CSEYMEQVIVLLEQEEMRAKKYLHESSVEKVITLCQKVMIKAHKDKLHAV 314
Query: 280 NVAKIVNSDKNDVLSRLLAISSSQKDKNVIFDQLSQFIVKEITSIEIDTXXXXXXXXXXX 339
I N + D+ + + Q +V+ + +++ K+ +E
Sbjct: 315 CHDLITNEENKDLRNMYRLLKPIQAGLSVMVKEFEEYVKKK--GLEA-VSRLTGENVPQQ 371
Query: 340 WIQELIKLKDKYQELGSHLNSAQAAGFKCINEAFGKAFSQ------IKIFPEFLSLYFDN 393
+++ ++++ +K+ ++ + + +++A + + E L+ Y D
Sbjct: 372 FVENVLRVYNKFNDMKTAVFMDDGEFSSGLDKALQGVVNSKEPGQSVPKASERLARYTDG 431
Query: 394 YLKSEPSAM-----DSNIRKCVQFFKLFKDKDAFEIIYXXXXXXXXXXXXXNVLREQELI 448
LK + ++ + + F+ +DKD F+ Y + +EL+
Sbjct: 432 LLKKSTKGLSETDLEAKLDSAIVIFRYIEDKDIFQKFYSKMLANRLIASTSISMDAEELM 491
Query: 449 F-LLQEDVGTSYTSKLRGMLRDLHSSNTFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMN 507
L++ G +TS L++ N + ++ D++ L + P
Sbjct: 492 INKLKQACGYEFTSSW-----PLNAPQLSTNSNNQTAQ--DVANFHLPRILQP------- 537
Query: 508 RDVIVPDSFAAIRNEYENRYAKTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGII 567
+ E+E Y H+GR L W +++S ++ + + + M ++
Sbjct: 538 -----------VIQEFEKFYTGKHNGRKLTWLFNMSQGDVRLTYLDKQYVAQMYVYQMAA 586
Query: 568 FMLFKEHESLTFDEIVELTNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSIN 627
+ F+ +++ +I E + + K + ++ + + ++++ + +N
Sbjct: 587 LLCFERRDAILVKDIGEEIGVSGDYLLKTIRTI-----LDVTLLTCDDQNLTADSLVRLN 641
Query: 628 QGFTAPQRKVKVLMVLMNTRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYH 687
T+ + K + L + N + + +V + R + A+ RIMK + L H
Sbjct: 642 MSMTSKRMKFR----LQAPQVNKAVEKEQEAVANTVSQDRKYYMECAIVRIMKTRKVLKH 697
Query: 688 SELQDKVA-LSIPLFEMSPSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
+ L ++ + F K S+E L+ YIQR D Y YL
Sbjct: 698 NALVTEIMDQTKGRFSPDVPFIKKSIEDLIEKMYIQRT-DQNDEYQYL 744
>7294516 [D] KOG2166 Cullins
Length = 670
Score = 60.1 bits (144), Expect = 1e-08
Identities = 83/390 (21%), Positives = 151/390 (38%), Gaps = 28/390 (7%)
Query: 354 LGSHLNSAQAAGFKCINEAF--GKAFSQIKIFPEFLSLYFDNYLKSEPSAMDS--NIRKC 409
L H A+ C E G+ ++ + + +SE + +D I KC
Sbjct: 300 LRDHTKLAEVVDAVCKEEINRKGQIIDPTRLLVTYANELMTKRQESEEAIIDELKRIVKC 359
Query: 410 VQFFKLFKDKDAFEIIYXXXXXXXXXXXXXNVLREQELIF-LLQEDVGTSYTSKLRGMLR 468
V+F D+ F +Y + +++ LL + + T + LR
Sbjct: 360 VEFLS---DEYKFIDMYLKALRIRQINETSTSDGVESIMYSLLNKKMANFVTRCIYVQLR 416
Query: 469 DLHSSNTFMQKNGKLSKTRDISVNV-LTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRY 527
D+ T ++ ++ I + + GS N ++ +PD E+ Y
Sbjct: 417 DVDKLRTLKKEFQDHLNSKGIKLGFDFRPKCFKNDGSFENFNLTLPDELQQAWKEFRIFY 476
Query: 528 A--KTHSGRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVEL 585
K S +++ N LS+ EI S + L + + MLF HE T E+V
Sbjct: 477 EARKLQSKAIIQLNNELSSGEITCHLNQSVYILEVSTLQMAVLMLFNRHERFTEQELVTA 536
Query: 586 TNLPQQEVRKNLISMSVAPKTKILQKSPPGKSISNTDMFSINQGFTAPQRKVKVLMVLMN 645
+ + +++ L + + ++ + IN FT +R++ L
Sbjct: 537 LGVELETLQEALKQIKFLVYIE----------VNKVNYIEINMDFTNRKRRLFCNEPLPR 586
Query: 646 TRPNATNDSTRSSVEKKLLDSRLSVINAAVTRIMKQDRKLYHSELQDKVALSI-PLFEMS 704
+S +E K+ R ++AA+ RIMK ++L +SEL V + +
Sbjct: 587 ---KMRKIEEKSEIELKI--RRDKQVDAAIVRIMKGQKQLEYSELISLVYEELKDRVKPQ 641
Query: 705 PSLFKMSLEYLLNNEYIQRDFDNTTMYHYL 734
S K L+YL+ EY++RD + +Y YL
Sbjct: 642 VSFIKKRLDYLVEREYLERD-NYYNIYRYL 670
>At1g59790 [D] KOG2166 Cullins
Length = 374
Score = 58.2 bits (139), Expect = 5e-08
Identities = 70/311 (22%), Positives = 132/311 (41%), Gaps = 47/311 (15%)
Query: 14 ISNRRYSRKTE-GLDEQWAILQNGIDK---IFDGKVTELSFE----KLYTTVYGLVLTKN 65
+ +RR SR + +E W+ +Q GI K I +G+ + KLYT +Y + + ++
Sbjct: 1 MDSRRMSRPRQIKFEEGWSNIQKGITKLIRILEGEPEPTFYFSECFKLYTIIYDMCVQRS 60
Query: 66 --GPQLHERLSRQLSDHFGKVRTSFDGITRAEALNLLNQV---WEKQKVYLSQISDVFIY 120
QL+E+ + + D+ ++T + ++L ++ W K+ + +S F+Y
Sbjct: 61 DYSQQLYEKYRKVIEDY--TIQTVLPSLREKHDEDMLRELVKRWNNHKIMVKWLSKFFVY 118
Query: 121 MDSVYSKREN--KPDVMSLGSRLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDIL 178
+D +R P + +G FL V + T K ++ I++ RE G I
Sbjct: 119 IDRHLVRRSKIPIPSLDEVGLTCFLDLVYCEMQSTAKEVVIALIHKERE------GEQID 172
Query: 179 KNAIAVLNSLELKEGMSSV--FLMEFEPFLLDSTEAYYKNLHSQLIAEQDETRWKDFXXX 236
+ + + + ++ GM ++ + +FE F+L T +YY S+ +E D+
Sbjct: 173 RALVKNVLDIYVENGMGTLEKYEEDFESFMLQDTASYYSRKASRW---TEEDSCPDYMIK 229
Query: 237 XXXXXXXXKICCNIFEDQDTILKLHNIAE-----------RVLVTDNIQEIAIYNVAKIV 285
C E + LH+I E V+VT N E + ++
Sbjct: 230 VEE--------CLKMERERVTHYLHSITEPKLVEKIQNELLVMVTKNRLENEHSGFSALL 281
Query: 286 NSDKNDVLSRL 296
DK + LSR+
Sbjct: 282 RDDKKNDLSRI 292
>ECU07g0860 [D] KOG2166 Cullins
Length = 742
Score = 54.7 bits (130), Expect = 5e-07
Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 17/176 (9%)
Query: 413 FKLFKDKDAFEIIYXXXXXXXXXXXXXNVLREQELIFLLQEDVGTSYTSKLRGMLRDLHS 472
+K+ ++K F +Y N+ E++LI L++ + K M+ D+
Sbjct: 464 YKMVENKHVFYEMYLSGLGKRLLEGNPNLQEERKLISLMKRKSNQDFMKKAETMIADISI 523
Query: 473 SNTFMQKNGKLSKTRDISVNVLTNMFWPLQGSDMNRDVIVPDSFAAIRNEYENRYAKTHS 532
S ++ +K D V +LT +WP+Q ++ +P I+ Y++++ K
Sbjct: 524 SLSY-------NKDVDRFVWILTQAYWPMQAE--SQSTRIPAPLEMIKKVYDSKFNK--- 571
Query: 533 GRLLEWNYHLSTVEIAYQFRNSYHELSMPMFSGIIFMLFKEHESLTFDEIVELTNL 588
+ L W +HL +V + R E+ M + + LF +HE + F++++ L +
Sbjct: 572 -KRLHWVWHLGSV--CVEIRGV--EIQMNVLQYSVVDLFNKHEEIDFEKVLGLVKM 622
>At1g59800 [D] KOG2166 Cullins
Length = 255
Score = 50.4 bits (119), Expect = 9e-06
Identities = 43/210 (20%), Positives = 100/210 (47%), Gaps = 22/210 (10%)
Query: 29 QWAILQNGIDKIF---DGKVTELSFEK-----LYTTVYGLVLTKNGPQLHERLSRQLSDH 80
+W+ +Q G K+ +G+ +E +F + ++T Y + KN QL+++ R+L ++
Sbjct: 12 EWSNIQQGFTKLIRMIEGE-SEPAFNQEIMMMMHTATYRICAYKNPQQLYDKY-RELIEN 69
Query: 81 FGKVRTSFDGITRAEALNLLNQV---WEKQKVYLSQISDVFIYMDSVYSKRENKPDVMSL 137
+ ++T + +L ++ W K+ + S +Y+D + ++ P + +
Sbjct: 70 YA-IQTVLPSLREKHDECMLRELAKRWNAHKLLVRLFSRRLVYLDDSFLSKKGLPSLREV 128
Query: 138 GSRLFLKEVVEHVSGTLKSSLVDEINQARESAAQYSGFDILKNAIAVLNSLELKEGMSSV 197
G F +V + +++ I++ RE + ++++N I V ++ GM ++
Sbjct: 129 GLNCFRDQVYREMQSMAAEAILALIHKEREG--EQIDRELVRNVIDVF----VENGMGTL 182
Query: 198 --FLMEFEPFLLDSTEAYYKNLHSQLIAEQ 225
+ +FE +L T +YY + S+ I E+
Sbjct: 183 KKYEEDFERLMLQDTASYYSSKASRWIQEE 212
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.134 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,946,429
Number of Sequences: 60738
Number of extensions: 1561170
Number of successful extensions: 4504
Number of sequences better than 1.0e-05: 33
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 4344
Number of HSP's gapped (non-prelim): 51
length of query: 735
length of database: 30,389,216
effective HSP length: 114
effective length of query: 621
effective length of database: 23,465,084
effective search space: 14571817164
effective search space used: 14571817164
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)