ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4629 good IE KOG1430 Amino acid transport and metabolism C-3 sterol dehydrogenase/3-beta-hydroxysteroid dehydrogenase and related dehydrogenases
r_klactIII4629 good IE KOG1430 Lipid transport and metabolism C-3 sterol dehydrogenase/3-beta-hydroxysteroid dehydrogenase and related dehydrogenases
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4629 1637489 1636437 -351
(351 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YGL001c [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyster... 573 e-163
SPBC3F6.02c [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxy... 307 1e-83
Hs8393516 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 222 7e-58
At1g47290 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 187 2e-47
At2g26260 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 184 2e-46
Hs21553311 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxys... 155 8e-38
At2g33630 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 136 4e-32
At2g43420 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 119 9e-27
Hs19923621 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxys... 111 2e-24
Hs4504507 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 105 1e-22
Hs4504509 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyst... 100 4e-21
CE07577 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyster... 99 1e-20
At4g33360 [V] KOG1502 Flavonol reductase/cinnamoyl-CoA reductase 81 2e-15
CE29623 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyster... 81 3e-15
CE20185 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyster... 79 8e-15
Hs17488989 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxys... 69 1e-11
7294013 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxyster... 67 5e-11
At3g14790 [G] KOG0747 Putative NAD+-dependent epimerases 65 2e-10
Hs20533350 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxys... 64 4e-10
At4g23920 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 64 4e-10
At1g78570 [G] KOG0747 Putative NAD+-dependent epimerases 64 4e-10
At1g53500 [G] KOG0747 Putative NAD+-dependent epimerases 63 6e-10
At1g12780 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 62 1e-09
Hs7657641 [G] KOG0747 Putative NAD+-dependent epimerases 62 1e-09
At4g10960 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 61 3e-09
At1g63180 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 58 2e-08
SPBPB2B2.12c [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinov... 57 4e-08
SPBC365.14c [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovo... 55 1e-07
Hs4503891 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 55 1e-07
Hs18601393 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxys... 55 1e-07
Hs14725159 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovos... 55 1e-07
YDR541c [V] KOG1502 Flavonol reductase/cinnamoyl-CoA reductase 54 4e-07
YBR019c_1 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 53 6e-07
At1g30620 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 53 8e-07
At5g44480 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 51 2e-06
At1g64440 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 51 3e-06
7291983 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose s... 51 3e-06
At2g34850 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose... 50 6e-06
>YGL001c [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 349
Score = 573 bits (1477), Expect = e-163
Identities = 273/348 (78%), Positives = 307/348 (87%)
Query: 4 SDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQG 63
S + SVL+IGGSGFLGLHLIQQF ++ P+P IH+FDVR LP+++SKQFTF+ I FH+G
Sbjct: 2 SKIDSVLIIGGSGFLGLHLIQQFFDINPKPDIHIFDVRDLPEKLSKQFTFNVDDIKFHKG 61
Query: 64 DLTSPADVRKAIETSGATIVVHSASPMHGNSQEIYEKVNVKGTKNLLTVAKQCRVKAVVY 123
DLTSP D+ AI S A +VVH ASPMHG + +IY+ VNVKGT+N++ + K+C V +VY
Sbjct: 62 DLTSPDDMENAINESKANVVVHCASPMHGQNPDIYDIVNVKGTRNVIDMCKKCGVNILVY 121
Query: 124 TSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIALRPAG 183
TSSAGVIFNGQD+HNADETWPIPEVPMD YNETKAIAE+MVL ANDP +DF T+ALRPAG
Sbjct: 122 TSSAGVIFNGQDVHNADETWPIPEVPMDAYNETKAIAEDMVLKANDPSSDFYTVALRPAG 181
Query: 184 IFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLNPTTAAL 243
IFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLL+P T
Sbjct: 182 IFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLDPKTRTA 241
Query: 244 VSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFFSKLLGKEP 303
VSGETFFITNDTPTYFWALARTVWKADGHIDK VIVL RP+AI AGYLS++ SK+LGKEP
Sbjct: 242 VSGETFFITNDTPTYFWALARTVWKADGHIDKHVIVLKRPVAICAGYLSEWVSKMLGKEP 301
Query: 304 GLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTLAWMDEGL 351
GLTPFRVKIVCAYRYHNI+KAK+LLGY PRV IEEGI +TLAWMDEGL
Sbjct: 302 GLTPFRVKIVCAYRYHNIAKAKKLLGYTPRVGIEEGINKTLAWMDEGL 349
>SPBC3F6.02c [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 340
Score = 307 bits (787), Expect = 1e-83
Identities = 170/348 (48%), Positives = 222/348 (62%), Gaps = 20/348 (5%)
Query: 6 VKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDV---RPLPDRISKQFTFDPSTITFHQ 62
+ SVL+IG SGFLG H+I+Q E + +I FD+ L + QFT +
Sbjct: 3 MNSVLVIG-SGFLGGHIIRQLCE-RENLRIAAFDLFENEKLLHELHGQFTM-------YT 53
Query: 63 GDLTSPADVRKAIETSGATIVVHSASPMHGNSQEIYEKVNVKGTKNLLTVAKQCRVKAVV 122
GDLT D+ + E +V+H+ASP+H +++IY +VNV GT N++ ++ V A+V
Sbjct: 54 GDLTKQGDIERVFEEFHPRVVIHTASPVHNLARDIYFEVNVDGTANIIKACQKFNVDALV 113
Query: 123 YTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIALRPA 182
YTSSAGV+FNG D+ N DE+ PIPEV MD YNE+KA+AE+ VL A+ T ALR A
Sbjct: 114 YTSSAGVVFNGADLINVDESQPIPEVHMDAYNESKALAEKQVLEAS--SESLKTAALRVA 171
Query: 183 GIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLL--NPTT 240
G+FGPGDRQLVPG+ V K GQ+KFQ+GDN NLFD+TY N A AH+LA LL NPT
Sbjct: 172 GLFGPGDRQLVPGMLSVLKNGQTKFQLGDNLNLFDFTYIENAAYAHLLAMDNLLSSNPT- 230
Query: 241 AALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFFSKLLG 300
+G+ FFITN YFW AR +W GH+ +I RP+ + +++ L
Sbjct: 231 ---ANGQVFFITNGQVIYFWDFARAIWAHAGHVPPYIIKFPRPVGMLLATAAEWVCYFLK 287
Query: 301 KEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTLAWMD 348
KEPG T FRV+ CA RY NI KA+++L Y P VD+EEGIRRTLAWMD
Sbjct: 288 KEPGFTRFRVQFSCANRYFNIQKAEDVLKYHPIVDLEEGIRRTLAWMD 335
>Hs8393516 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 373
Score = 222 bits (565), Expect = 7e-58
Identities = 134/348 (38%), Positives = 196/348 (55%), Gaps = 20/348 (5%)
Query: 1 MSSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITF 60
++ + K +IGGSGFLG H+++Q L ++VFD+ Q FD + F
Sbjct: 32 VNQNQAKRCTVIGGSGFLGQHMVEQL--LARGYAVNVFDI---------QQGFDNPQVRF 80
Query: 61 HQGDLTSPADVRKAIETSGATIVVHSASPM-HGNSQEIYEKVNVKGTKNLLTVAKQCRVK 119
GDL S D+ A++ G V H ASP N++E++ +VN GTKN++ K+ V+
Sbjct: 81 FLGDLCSRQDLYPALK--GVNTVFHCASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQ 138
Query: 120 AVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIAL 179
++ TSSA VIF G DI N E P P+D Y ETK + E VL ANDPE +FLT A+
Sbjct: 139 KLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAI 198
Query: 180 RPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLNPT 239
RP GIFGP D QLVP L + A+ G+ KF IG+ NL D+T+ NV H+LAA++L +
Sbjct: 199 RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS 258
Query: 240 TAALVSGETFFITNDTPTYFWA-LARTVWKADGHIDKRVIV--LNRPMAIAAGYLSQFFS 296
T + G+ F ITND P FW L+R + + K I + +A+ L S
Sbjct: 259 T---LGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVIS 315
Query: 297 KLLGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTL 344
++ +P TP RV + + Y++ +AK+ +GYQP V +++ + RT+
Sbjct: 316 PVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTV 363
>At1g47290 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 439
Score = 187 bits (475), Expect = 2e-47
Identities = 122/350 (34%), Positives = 186/350 (52%), Gaps = 22/350 (6%)
Query: 10 LLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFT------FDPSTITFHQG 63
++ GG GF HL++ + + + D+ P + T + +
Sbjct: 13 VVTGGRGFAARHLVEMLVRYQ-MFHVRIADLAPAIVLNPHEETGILGEAIRSGRVQYVSA 71
Query: 64 DLTSPADVRKAIETSGATIVVHSASPMHG-NSQEIYEKVNVKGTKNLLTVAKQCRVKAVV 122
DL + V K + GA +V H A+P N+ ++ VNV+GT N++ + VK ++
Sbjct: 72 DLRNKTQVVKGFQ--GAEVVFHMAAPDSSINNHQLQYSVNVQGTTNVIDACIEVGVKRLI 129
Query: 123 YTSSAGVIFNGQDIH---NADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIAL 179
YTSS V+F+G +H NADE+ P P D Y+ TKA E ++L AN + LT +
Sbjct: 130 YTSSPSVVFDG--VHGTLNADESLPYPPKHNDSYSATKAEGEALILKANG-RSGLLTCCI 186
Query: 180 RPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLN-P 238
RP+ IFGPGD+ +VP L A+ G+SKF IGD +N +D+TY NV AHV A + L +
Sbjct: 187 RPSSIFGPGDKLMVPSLVTAARAGKSKFIIGDGSNFYDFTYVENVVHAHVCAERALASGG 246
Query: 239 TTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFFSKL 298
A +G+ +FITN P FW + + G+ ++ I + + + YL + KL
Sbjct: 247 EVCAKAAGQAYFITNMEPIKFWEFMSQLLEGLGY-ERPSIKIPASLMMPIAYLVELAYKL 305
Query: 299 LG----KEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTL 344
LG K P LTP RV+++ R + SKAK+ LGY P V ++EGI+RT+
Sbjct: 306 LGPYGMKVPVLTPSRVRLLSCNRTFDSSKAKDRLGYSPVVPLQEGIKRTI 355
>At2g26260 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 390
Score = 184 bits (467), Expect = 2e-46
Identities = 123/348 (35%), Positives = 185/348 (52%), Gaps = 18/348 (5%)
Query: 10 LLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRP--LPDRISKQFTFDPST----ITFHQG 63
++ GG GF HL++ + + + D+ P + D D + +
Sbjct: 13 VVTGGRGFAARHLVEMLVRYE-MFCVRIADLAPAIMLDPQEGNGVLDEGLRSGRVQYISA 71
Query: 64 DLTSPADVRKAIETSGATIVVHSASPMHG-NSQEIYEKVNVKGTKNLLTVAKQCRVKAVV 122
DL + V KA + GA +V H A+P N+ ++ VNV+GT+N++ VK ++
Sbjct: 72 DLRDKSQVVKAFQ--GAEVVFHMAAPDSSINNHQLQYSVNVQGTQNVIDACVDVGVKRLI 129
Query: 123 YTSSAGVIFNG-QDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIALRP 181
YTSS V+F+G I N E+ P D Y+ TKA EE+++ AN N LT +RP
Sbjct: 130 YTSSPSVVFDGVHGILNGTESMAYPIKHNDSYSATKAEGEELIMKANG-RNGLLTCCIRP 188
Query: 182 AGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLN-PTT 240
+ IFGPGDR LVP L A+ G+SKF IGD NNL+D+TY NVA AHV A + L +
Sbjct: 189 SSIFGPGDRLLVPSLVAAARAGKSKFIIGDGNNLYDFTYVENVAHAHVCAERALASGGDV 248
Query: 241 AALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFFSKLLG 300
+ +G+ +FITN P FW + G+ ++ I + + + +L + K+LG
Sbjct: 249 STKAAGQAYFITNMEPIKFWEFMSQLLDGLGY-ERPSIKIPAFIMMPIAHLVELTYKVLG 307
Query: 301 ----KEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTL 344
P LTP RV+++ R + +KAK+ LGY P V ++EGIRRT+
Sbjct: 308 PYGMTVPQLTPSRVRLLSCSRTFDSTKAKDRLGYAPVVPLQEGIRRTI 355
>Hs21553311 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 383
Score = 155 bits (392), Expect = 8e-38
Identities = 119/357 (33%), Positives = 184/357 (51%), Gaps = 35/357 (9%)
Query: 4 SDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHV--FDVRPLPDRISKQFTFDPSTITFH 61
S +SVL+ GGSG+ G L + Q +HV FD+ I P I F
Sbjct: 6 SQKESVLITGGSGYFGFRLGCALN----QNGVHVILFDISSPAQTI-------PEGIKFI 54
Query: 62 QGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQ---EIYEKVNVKGTKNLLTVAKQCR 117
QGD+ +DV KA + + T V H AS M G Q + ++VNV+GT N+L V ++ R
Sbjct: 55 QGDIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRR 114
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEVPM----DGYNETKAIAEEMVLSANDPEND 173
V +VYTS+ VIF GQ I N DE+ +P +P+ D Y+ TK+IAE+ VL AN D
Sbjct: 115 VPRLVYTSTFNVIFGGQVIRNGDES--LPYLPLHLHPDHYSRTKSIAEQKVLEANATPLD 172
Query: 174 -----FLTIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAH 228
T ALRPAGI+GPG+++ +P + + G KF GD +L ++ + N+ AH
Sbjct: 173 RGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAH 232
Query: 229 VLAAQKLLNPTTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAA 288
+LA++ L + SG+ +FI++ P + R + + G+ L +
Sbjct: 233 ILASE-ALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPST-RLPLTLVYCF 290
Query: 289 GYLSQFFSKLLGK----EPGLTPFRVKIVCAYRYHNISKAKELLGYQPR-VDIEEGI 340
+L++ +LG+ +P LT V Y ++ KAK+ LGY+ + D++E +
Sbjct: 291 AFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAV 347
>At2g33630 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 480
Score = 136 bits (343), Expect = 4e-32
Identities = 110/366 (30%), Positives = 183/366 (49%), Gaps = 36/366 (9%)
Query: 10 LLIGGSGFLGLHLIQQFSELKPQPQIHVFDVR---PLPDRISKQFTFDPSTITFHQGDLT 66
++ GG GF+G L + + Q+ FD+R P D + S + QGD+T
Sbjct: 15 VVTGGLGFVGAALCLELVR-RGARQVRSFDLRHSSPWSDDLKN------SGVRCIQGDVT 67
Query: 67 SPADVRKAIETSGATIVVHSAS-PMHGNSQEIY---EKVNVKGTKNLLTVAKQCRVKAVV 122
DV A++ GA V+H AS M G + ++VN+ GT N+L A + + +V
Sbjct: 68 KKQDVDNALD--GADCVLHLASYGMSGKEMLRFGRCDEVNINGTCNVLEAAFKHEITRIV 125
Query: 123 YTSSAGVIFNGQDIHNADETWPIPEVP--MDGYNETKAIAEEMVLSAN-----DPENDFL 175
Y S+ V+F G++I N +E P + +D Y+ TK+IAE++VL +N +
Sbjct: 126 YVSTYNVVFGGKEILNGNEGLPYFPLDDHVDAYSRTKSIAEQLVLKSNGRPFKNGGKRMY 185
Query: 176 TIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKL 235
T A+RPA I+GPG+ + +P + + KLG + F+IG+ + DW Y N+ A +LA+ L
Sbjct: 186 TCAIRPAAIYGPGEDRHLPRIVTLTKLGLALFKIGEPSVKSDWIYVENLVLAIILASMGL 245
Query: 236 LNPTTA----ALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYL 291
L+ + +G+ +F+++ P + R + K+ + D ++ P A++ G +
Sbjct: 246 LDDIPGREGQPVAAGQPYFVSDGYPVNTFEFLRPLLKSLDY-DLPKCTISVPFALSLGKI 304
Query: 292 SQFF--------SKLLGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRT 343
Q F SK +P + P V V Y + KAKE LGY P +EG+ T
Sbjct: 305 FQGFYTVLYPWLSKSWLPQPLVLPAEVYKVGVTHYFSYLKAKEELGYVPFKSSKEGMAAT 364
Query: 344 LAWMDE 349
+++ E
Sbjct: 365 ISYWQE 370
>At2g43420 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 437
Score = 119 bits (297), Expect = 9e-27
Identities = 87/283 (30%), Positives = 141/283 (49%), Gaps = 6/283 (2%)
Query: 58 ITFHQGDLTSPADVRKAIETSGATIVVH-SASPMHGNSQEIYEKVNVKGTKNLLTVAKQC 116
+ F DL+ V T G+ +V + A+ + + KV V+GT+N+++ ++
Sbjct: 115 LRFSGSDLSFGVTVLFLAVTEGSYVVFYMGATDLRSHDYFDCYKVIVQGTRNVISACRES 174
Query: 117 RVKAVVYTSSAGVIFNG-QDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFL 175
V+ ++Y S+A V+F+G Q I + DE+ P + KA AE ++ AN+ + L
Sbjct: 175 GVRKLIYNSTADVVFDGSQPIRDGDESLRRPLKFQSMLTDFKAQAEALIKLANNRDG-LL 233
Query: 176 TIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKL 235
T ALR + +FGPGD + VP L +AK G +KF +G N+ D+TY+ NV+ AH+ A + L
Sbjct: 234 TCALRSSIVFGPGDTEFVPFLVNLAKSGYAKFILGSGENISDFTYSENVSHAHICAVKAL 293
Query: 236 LNPTTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFF 295
+ V+G+ FFITN P FW + + G+ + + R + L
Sbjct: 294 --DSQMEFVAGKEFFITNLKPVRFWDFVSHIVEGLGYPRPSIKLPVRLVLYVFSLLKWTH 351
Query: 296 SKL-LGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIE 337
K LG + + R N + AK+ LGY P V +E
Sbjct: 352 EKEGLGSNYDTAHQYALLASSTRTFNCNAAKKHLGYTPVVTLE 394
>Hs19923621 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 369
Score = 111 bits (277), Expect = 2e-24
Identities = 104/358 (29%), Positives = 168/358 (46%), Gaps = 29/358 (8%)
Query: 10 LLIGGSGFLGLHLIQQFSELKPQ-PQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTSP 68
L+ GG GFLG H+++ + +P+ ++ VFD P ++ P +T QGD+T
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGP--WLEELKTGPVRVTAIQGDVTQA 70
Query: 69 ADVRKAIETSGATIVVHSAS--PMHGN-SQEIYEKVNVKGTKNLLTVAKQCRVKAVVYTS 125
+V A+ +GA +V+H+A + G S + +VNV+GT+N++ Q + +VYTS
Sbjct: 71 HEVAAAV--AGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTS 128
Query: 126 SAGVI---FNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPE----NDFLTIA 178
S V+ G + +E P V Y +KA+AE +VL AN + +T A
Sbjct: 129 SMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCA 188
Query: 179 LRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLNP 238
LRP GI+G G + + RQ +LG F+ + Y GNVA HVLAA++L
Sbjct: 189 LRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAAREL--E 246
Query: 239 TTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRP---------MAIAAG 289
A L+ G+ +F + +P + + + G R +V RP +A
Sbjct: 247 QRATLMGGQVYFCYDGSP--YRSYEDFNMEFLGPCGLR-LVGARPLLPYWLLVFLAALNA 303
Query: 290 YLSQFFSKLLGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTLAWM 347
L L+ P L P+ + + + KA+ GY+P E+ RT+ W+
Sbjct: 304 LLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILWV 361
>Hs4504507 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 373
Score = 105 bits (261), Expect = 1e-22
Identities = 107/368 (29%), Positives = 175/368 (47%), Gaps = 43/368 (11%)
Query: 8 SVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTF--DPSTITFHQGDL 65
S L+ G GFLG +I+ + K +I V D P+ + ++F+ + + +T +GD+
Sbjct: 5 SCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPE-LREEFSKLQNKTKLTVLEGDI 63
Query: 66 TSPADVRKAIETSGATIVVHSASPMHG---NSQEIYEKVNVKGTKNLLTVAKQCRVKAVV 122
+++A + ++++H+A + +E VNVKGT+ LL Q V +
Sbjct: 64 LDEPFLKRACQD--VSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI 121
Query: 123 YTSS---AG------VIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPE-- 171
YTSS AG +I NG + + TWP P Y +K +AE+ VL+AN
Sbjct: 122 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAP------YPHSKKLAEKAVLAANGWNLK 175
Query: 172 --NDFLTIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHV 229
T ALRP I+G G R L + + +G + + + Y GNVA AH+
Sbjct: 176 NGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTV-NPVYVGNVAWAHI 234
Query: 230 LAAQKLLNPTTAALVSGETFFITNDTPTYFW-ALARTVWKADG-HIDKRVIVLNRPMAIA 287
LA + L +P A + G+ ++I++DTP + L T+ K G +D R + P+++
Sbjct: 235 LALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSR---WSFPLSLM 291
Query: 288 --AGYLSQFFSKLLGKEPGLT---PFRVKIVC---AYRYHNISKAKELLGYQPRVDIEEG 339
G+L + S LL P T PF IV + + KA+ L Y+P EE
Sbjct: 292 YWIGFLLEIVSFLL--RPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEA 349
Query: 340 IRRTLAWM 347
++T+ W+
Sbjct: 350 KQKTVEWV 357
>Hs4504509 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 372
Score = 100 bits (248), Expect = 4e-21
Identities = 100/366 (27%), Positives = 168/366 (45%), Gaps = 39/366 (10%)
Query: 8 SVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTF--DPSTITFHQGDL 65
S L+ G G LG +++ E K +I D P+ + ++F+ + + +T +GD+
Sbjct: 4 SCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPE-LREEFSKLQNRTKLTVLEGDI 62
Query: 66 TSPADVRKAIETSGATIVVHSASPMHG---NSQEIYEKVNVKGTKNLLTVAKQCRVKAVV 122
+++A + ++V+H+A + +E VNVKGT+ LL Q V +
Sbjct: 63 LDEPFLKRACQD--VSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI 120
Query: 123 YTSS---AG------VIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSAND---P 170
YTSS AG +I NG + + TWP P Y +K +AE+ VL+AN
Sbjct: 121 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTP------YPYSKKLAEKAVLAANGWNLK 174
Query: 171 ENDFL-TIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHV 229
D L T ALRP I+G G L + + +G + + + Y GNVA AH+
Sbjct: 175 NGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTV-NPVYVGNVAWAHI 233
Query: 230 LAAQKLLNPTTAALVSGETFFITNDTPTYFWALARTVWKADG--HIDKRVIVLNRPMAIA 287
LA + L +P A V G+ ++I++DTP + + + +D R + P+ +
Sbjct: 234 LALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSR---WSLPLTLM 290
Query: 288 --AGYLSQFFSKLLGK----EPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIR 341
G+L + S LL +P V + + + KA+ L Y+P EE +
Sbjct: 291 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ 350
Query: 342 RTLAWM 347
+T+ W+
Sbjct: 351 KTVEWV 356
>CE07577 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 374
Score = 98.6 bits (244), Expect = 1e-20
Identities = 94/335 (28%), Positives = 148/335 (44%), Gaps = 26/335 (7%)
Query: 10 LLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTSPA 69
+++GG GFLG H+I ++ + +I V D P P K D S I++ +
Sbjct: 5 VIVGGGGFLGAHVISALQKIGCKERIIVVD--PCPQEF-KTIKIDKSNISYIKASFLDDK 61
Query: 70 DVRKAIETSGATIVVHSASPMH-----GNSQEIYEKVNVKGTKNLLTVAKQCRVKAVVYT 124
+ + +GA+ VVH A+ H G+ + ++ NV GTK L+ K VK +Y
Sbjct: 62 VLENIL--NGASAVVHLAAVGHTGLIAGDRKSVHN-FNVNGTKQLIKQCKALGVKRFLYA 118
Query: 125 SSAGVIFNGQDIHNADETWPIPEVP--MDGYNETKAIAEEMVLSANDPENDFLTIALRPA 182
SS V F G+ + N E P+P+ +D Y+ +KA AE VLS + P DF T+ LR
Sbjct: 119 SSVAVSFIGEPLDNVTEDDPLPDPKKYLDFYSASKAEAETYVLSQSTP--DFKTVCLRFR 176
Query: 183 GIFGPGDRQLVPGLRQVAKLGQSKFQIG-----DNNNLFDWTYAGNVADAHVLAAQKLLN 237
GI+GP D + +VA L ++ IG ++ + N A A LA Q L N
Sbjct: 177 GIYGPEDPNVT---LKVANLIKNGLFIGMVSAHGRESVSCASSGVNCAKAFALADQMLQN 233
Query: 238 PTTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFFSK 297
P + G ++I + + + A G + Y
Sbjct: 234 PDG---LHGRAYYILDGENVGQFQFWTPLVLALGKQPPSFYTPYDFIKAVVPYFQNVCYG 290
Query: 298 LLGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQP 332
+ P LT F + I+ ++I +A+ LGY+P
Sbjct: 291 VFKLPPLLTKFELSILAVDNTYSIERARRELGYEP 325
>At4g33360 [V] KOG1502 Flavonol reductase/cinnamoyl-CoA reductase
Length = 344
Score = 81.3 bits (199), Expect = 2e-15
Identities = 94/358 (26%), Positives = 152/358 (42%), Gaps = 55/358 (15%)
Query: 9 VLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTSP 68
+L+ G +G+LG L VR L R S P + GD+T
Sbjct: 15 ILVTGSTGYLGARLCHVLLR-------RGHSVRALVRRTSDLSDLPPE-VELAYGDVTDY 66
Query: 69 ADVRKAIETSGATIVVHSASPMHG--NSQEIYEKVNVKGTKNLLTVAKQCR-VKAVVYTS 125
+ A SG IV H+A+ + + VNV G KN+L K+ + V+ ++YTS
Sbjct: 67 RSLTDAC--SGCDIVFHAAALVEPWLPDPSRFISVNVGGLKNVLEAVKETKTVQKIIYTS 124
Query: 126 SA-------GVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIA 178
S G + N +HN E + E Y +KA+A++M L+A I
Sbjct: 125 SFFALGSTDGSVANENQVHN--ERFFCTE-----YERSKAVADKMALNA--ASEGVPIIL 175
Query: 179 LRPAGIFGPGDRQLVPGLRQVAKLGQSKFQ------IGDNNNLFDWTYAGNVADAHVLAA 232
L P IFGPG + VA++ +F IG + + +++ +V + HV A
Sbjct: 176 LYPGVIFGPGK---LTSANMVARMLIERFNGRLPGYIGSGTDRYSFSHVDDVVEGHVAAM 232
Query: 233 QKLLNPTTAALVSGETFFITNDTPTY---FWALARTVWKADGHIDKRVIVLNRPMAIAAG 289
+K GE + +T + ++ F A + + +N A G
Sbjct: 233 EKGR--------LGERYLLTGENASFKLVFDMAALITGTKKPNFSIPLWAIN-----AYG 279
Query: 290 YLSQFFSKLLGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTLAWM 347
+LS S++ GK P ++P V ++ ++ KAK LGY PR ++EG+ L W+
Sbjct: 280 WLSVLISRVTGKLPLISPPTVTVLRHQWSYSCDKAKLELGYNPR-SLKEGLEEMLPWL 336
>CE29623 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 643
Score = 80.9 bits (198), Expect = 3e-15
Identities = 83/333 (24%), Positives = 136/333 (39%), Gaps = 38/333 (11%)
Query: 10 LLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTSPA 69
++ GG GFLG HLI + + + V D P S FD S + + +
Sbjct: 8 VITGGGGFLGAHLIAALQKNGDRTKCIVVDPNPRLSHFSA-IDFDKSLVEYEKAQ----- 61
Query: 70 DVRKAIETSGATIVVHSASPMHGNSQEIYEKVNVKGTKNLLTVAKQCRVKAVVYTSSAGV 129
+E NV GTK L+ K V +Y+SS V
Sbjct: 62 -----------------------KHREYVYAFNVTGTKFLIEKCKFFGVPRFIYSSSIAV 98
Query: 130 IFNGQDIHNADET--WPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIALRPAGIFGP 187
+F G+ I+N DE+ +P+ +D Y+ +KA AE V S + + F T LR I+GP
Sbjct: 99 VFVGKPIYNCDESEPYPLKSEYLDIYSSSKAEAEAFVRSQSTIQ--FKTTCLRFRAIYGP 156
Query: 188 GDRQLVPGLRQVAK--LGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKLLNPTTAALVS 245
D + + Q+ + L K ++ + + N A LA Q+L +
Sbjct: 157 QDVTVAEKVVQMVRKNLFMVKISRHGRESVSNMSSGENCGLALHLANQELSKKEGS---H 213
Query: 246 GETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQFFSKLLGKEPGL 305
GE +FIT+ +++ + KA G V ++ S K+ P +
Sbjct: 214 GEVYFITDGETVGQYSVWSPLIKALGKTPPHHFVSCLLVSTFVSLSSYLCYKIFNSSPPM 273
Query: 306 TPFRVKIVCAYRYHNISKAKELLGYQPRVDIEE 338
T F ++++ ++I KA+ LGY P ++ E
Sbjct: 274 TRFELEVLITDNTYSIEKARRELGYCPEQNLFE 306
>CE20185 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 462
Score = 79.3 bits (194), Expect = 8e-15
Identities = 68/236 (28%), Positives = 113/236 (47%), Gaps = 8/236 (3%)
Query: 101 VNVKGTKNLLTVAKQCRVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIA 160
+N GT NLL A+ V+ +YTSS GV+F+G+ ++NA E P+ + Y E+KA A
Sbjct: 168 INAVGTMNLLIWARNSGVQRFIYTSSVGVVFSGEPMYNATEEVGYPDDFYNYYCESKAHA 227
Query: 161 EEMVLSANDPENDFLTIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIG--DNNNLFDW 218
E +V A+ + T LR GI+GPG++++ +V K + I N +
Sbjct: 228 ERIVQKASG--HRMRTTVLRFNGIYGPGEKRVT---ERVVKFMLTGMWIATCKPNGVEAQ 282
Query: 219 TYAGNVADAHVLAAQKLLNPTTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVI 278
T +VA+ + L + G+ + I + TP ++ + A G +
Sbjct: 283 TQLSSVANCIQGLVKAELALRWSDTPHGQIYNIMDKTPVGTFSFWTPLNIALGFSSSMIT 342
Query: 279 VLNRPMAIAAGYLSQFFSKLLGKEPGLTPFRVKIVCAYRYHNISKAKELLGYQPRV 334
V P+ + A YLSQ + + +P ++ V ++ NI KA+ LGY+P V
Sbjct: 343 VPATPIRLFA-YLSQIIADRMRIDPIVSVLEVDLLLVNNTFNIEKAERDLGYEPSV 397
>Hs17488989 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 280
Score = 68.9 bits (167), Expect = 1e-11
Identities = 80/285 (28%), Positives = 122/285 (42%), Gaps = 67/285 (23%)
Query: 8 SVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTS 67
S L+ G GFLG +I + + D++ L ++I +T +GD+
Sbjct: 5 SCLVTGAGGFLGQRIICLSNRYQ--------DLQELQNKIK---------LTVLEGDILD 47
Query: 68 PADVRKAIETSGATIVVHSASPMHG---NSQEIYEKVNVKG---------------TKNL 109
+++A + ++V+H+A + ++ VNVKG T+ L
Sbjct: 48 EPFLKRACQD--VSVVIHTACIIDVFGVTHRQSIMNVNVKGRGYFLTLKACSFWAGTQLL 105
Query: 110 LTVAKQCRVKAVVYTSS---AGVIFNGQDIHNADE------TWPIPEVPMDGYNETKAIA 160
L Q V +YTS+ AG + I NA E TW P Y +K +A
Sbjct: 106 LEACVQATVPVFIYTSTLQLAGPNSYKEIIENAHEEDFLENTWSAP------YPYSKKLA 159
Query: 161 EEMVLSAND---PENDFL-TIALRPAGIFGPGDRQLVPGLRQVAK-----LGQSKFQIGD 211
E+ VL+AN D L T ALRP I+G G L + + SKF +
Sbjct: 160 EKAVLAANGWTLKNGDTLYTCALRPMYIYGEGSPFLTANINEALNNNGILSSVSKFSTAN 219
Query: 212 NNNLFDWTYAGNVADAHVLAAQKLLNPTTAALVSGETFFITNDTP 256
Y GNVA AH+LA + L +P A V G+ ++I++DTP
Sbjct: 220 P------VYVGNVAWAHILALRALRDPKKAPSVLGQFYYISDDTP 258
>7294013 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 398
Score = 66.6 bits (161), Expect = 5e-11
Identities = 78/287 (27%), Positives = 126/287 (43%), Gaps = 38/287 (13%)
Query: 1 MSSSDVKSVLLIGGSGFLGLHLIQQFSELKPQ---PQIHVFDVRPLPDRISKQFTFDPST 57
M + + +L+ GGSGFLG HLI+Q E K + +I D+ P + I + T S
Sbjct: 1 MGNKSGEVLLVTGGSGFLGQHLIKQLLERKEELGIKEIRSLDIVPYKNNIGHEET---SL 57
Query: 58 ITFHQGDLTSPADVRKAIETSGATIVVHSASPM---HGNSQEIYEKVNVKGTKNLLTVAK 114
+ + D+ I +G V H A+ + + + E E+VNV GT ++ +
Sbjct: 58 LRTYVADIGGDLKALSPI-FNGVDGVFHCAASVKIEYPPNYEELERVNVNGTLAVVDLCI 116
Query: 115 QCRVKAVVYTSSAGVI---FNGQDIHNA--DETWPIPEVP---------------MDGYN 154
Q VK +VYTS V F G+ +A + T + P + GY
Sbjct: 117 QNNVKRLVYTSCTSVCFVPFKGRSTFSAVINSTESKTDTPTLDSSTLWEQDNQFLIPGYA 176
Query: 155 ETKAIAEEMVLSANDP----ENDFL-TIALRPAGIFGPGDRQLVPGLRQ-VAKLGQSKFQ 208
+K AE +VL++N + ++L T A+R +G D + + ++ G +
Sbjct: 177 SSKLRAENIVLNSNGAPLHNQKEYLATSAMRAPLTYGECDSHFITEIFDFLSTRGWVFPR 236
Query: 209 IGDNNNLFDWTYAGNVADAHVLAAQKLLNPTTAALVSGETFFITNDT 255
I YAGNVA H+ A + L + V+G F+T+DT
Sbjct: 237 IAGVGGKQQLVYAGNVAWGHICAYKAL--KVSDKAVNGLPVFVTDDT 281
>At3g14790 [G] KOG0747 Putative NAD+-dependent epimerases
Length = 664
Score = 64.7 bits (156), Expect = 2e-10
Identities = 89/368 (24%), Positives = 147/368 (39%), Gaps = 66/368 (17%)
Query: 1 MSSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPS---- 56
M++ K++L+ G +GF+ H+ + P +I V D D S +PS
Sbjct: 1 MATYKPKNILITGAAGFIASHVANRLVRSYPDYKIVVLDKL---DYCSNLKNLNPSKSSP 57
Query: 57 TITFHQGDLTSPADVRKAIETSGATIVVHSASPMH-----GNSQEIYEKVNVKGTKNLLT 111
F +GD+ S V + T ++H A+ H GNS E + K N+ GT LL
Sbjct: 58 NFKFVKGDIASADLVNYLLITEEIDTIMHFAAQTHVDNSFGNSFE-FTKNNIYGTHVLLE 116
Query: 112 VAKQC-RVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDP 170
K +++ ++ S+ V + + +P + Y+ TKA AE +V+ A
Sbjct: 117 ACKVTGQIRRFIHVSTDEVYGETDEDASVGNHEASQLLPTNPYSATKAGAEMLVM-AYGR 175
Query: 171 ENDFLTIALRPAGIFGPGD--RQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAH 228
I R ++GP +L+P +A G+ GD +N+ + Y +VA+A
Sbjct: 176 SYGLPVITTRGNNVYGPNQFPEKLIPKFILLAMNGKPLPIHGDGSNVRSYLYCEDVAEAF 235
Query: 229 VLAAQKLLNPTTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAA 288
+ K GE + N T ++RVI
Sbjct: 236 EVVLHK-----------GEVNHVYNIGTTR---------------ERRVI---------- 259
Query: 289 GYLSQFFSKLLGKEPGLT-------PFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIR 341
++ SKL G +P T PF + RY + + LG+ R + EEG+R
Sbjct: 260 -DVANDISKLFGIDPDSTIQYVENRPFNDQ-----RYFLDDQKLKKLGWCERTNWEEGLR 313
Query: 342 RTLAWMDE 349
+T+ W E
Sbjct: 314 KTMEWYTE 321
>Hs20533350 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 211
Score = 63.5 bits (153), Expect = 4e-10
Identities = 59/258 (22%), Positives = 106/258 (40%), Gaps = 61/258 (23%)
Query: 4 SDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHV--FDVRPLPDRISKQFTFDPSTITFH 61
S ++ L+ GG G+ G HL + Q +HV FD+ I P I F
Sbjct: 6 SPKETFLITGGGGYFGFHLGHALN----QKGVHVILFDISSPAQTI-------PEGIKFV 54
Query: 62 QGDLTSPADVRKAI-ETSGATIVVHSASPMHGNSQEIYEKVNVKGTKNLLTVAKQCRVKA 120
GD+ +D+ KA+ + S ++ +Q + ++V++ T N+L V ++
Sbjct: 55 HGDIRHLSDIEKALTQMSHVCSILPLMVWKEQLNQNLIKEVSIGSTDNILQVCQR----- 109
Query: 121 VVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPEND-----FL 175
+ + E+ VL A D
Sbjct: 110 ------------------------------------RGVPEKKVLEAKSTPLDRGDGVLR 133
Query: 176 TIALRPAGIFGPGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQKL 235
T +LRPAGI+GPG+++ +P + + KF GD +L + + N+ AH+LA++
Sbjct: 134 TCSLRPAGIYGPGEQRHLPRIVSYIEKDTFKFVCGDPRSLVESVHVDNLVQAHILASE-A 192
Query: 236 LNPTTAALVSGETFFITN 253
L + SG+ +F+++
Sbjct: 193 LRADKGHIASGQPYFVSD 210
>At4g23920 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 350
Score = 63.5 bits (153), Expect = 4e-10
Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 29/255 (11%)
Query: 7 KSVLLIGGSGFLGLHLIQQFSELKPQPQI---HVFDVRPLPDRISKQFTFDPSTITFHQG 63
KSVL+ GG+G++G H + Q E + + R+ K + + ++FHQ
Sbjct: 3 KSVLVTGGAGYIGSHTVLQLLEGGYSAVVVDNYDNSSAASLQRVKKLAGENGNRLSFHQV 62
Query: 64 DLTSPADVRKAIETSGATIVVHSAS-PMHGNSQE---IYEKVNVKGTKNLLTVAKQCRVK 119
DL + K + V+H A G S E +Y N+ GT LL V Q K
Sbjct: 63 DLRDRPALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNIVGTVTLLEVMAQYGCK 122
Query: 120 AVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIAL 179
+V++SSA V +++ +E+ P + Y TK EE+ + ++++ I L
Sbjct: 123 NLVFSSSATVYGWPKEVPCTEES---PISATNPYGRTKLFIEEICRDVHRSDSEWKIILL 179
Query: 180 R--------PAGIFG-----------PGDRQLVPGLRQVAKLGQSKFQIGDNNNLFDWTY 220
R P+G G P +Q+ G R + + ++ D + D+ +
Sbjct: 180 RYFNPVGAHPSGYIGEDPLGVPNNLMPYVQQVAVGRRPHLTVFGTDYKTKDGTGVRDYIH 239
Query: 221 AGNVADAHVLAAQKL 235
++AD H+ A +KL
Sbjct: 240 VMDLADGHIAALRKL 254
>At1g78570 [G] KOG0747 Putative NAD+-dependent epimerases
Length = 669
Score = 63.5 bits (153), Expect = 4e-10
Identities = 67/249 (26%), Positives = 110/249 (43%), Gaps = 23/249 (9%)
Query: 1 MSSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPS---- 56
M+S K++L+ G +GF+ H+ + P +I V D D S +PS
Sbjct: 1 MASYTPKNILITGAAGFIASHVANRLIRSYPDYKIVVLDKL---DYCSNLKNLNPSKHSP 57
Query: 57 TITFHQGDLTSPADVRKAIETSGATIVVHSASPMH-----GNSQEIYEKVNVKGTKNLLT 111
F +GD+ S V + T G ++H A+ H GNS E + K N+ GT LL
Sbjct: 58 NFKFVKGDIASADLVNHLLITEGIDTIMHFAAQTHVDNSFGNSFE-FTKNNIYGTHVLLE 116
Query: 112 VAKQC-RVKAVVYTSSAGVIFNGQD---IHNADETWPIPEVPMDGYNETKAIAEEMVLSA 167
K +++ ++ S+ V + + N + + +P P Y+ TKA AE +V+ A
Sbjct: 117 ACKVTGQIRRFIHVSTDEVYGETDEDALVGNHEASQLLPTNP---YSATKAGAEMLVM-A 172
Query: 168 NDPENDFLTIALRPAGIFGPGD--RQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVA 225
I R ++GP +L+P +A GQ GD +N+ + Y +VA
Sbjct: 173 YGRSYGLPVITTRGNNVYGPNQFPEKLIPKFILLAMRGQVLPIHGDGSNVRSYLYCEDVA 232
Query: 226 DAHVLAAQK 234
+A + K
Sbjct: 233 EAFEVVLHK 241
>At1g53500 [G] KOG0747 Putative NAD+-dependent epimerases
Length = 667
Score = 63.2 bits (152), Expect = 6e-10
Identities = 85/359 (23%), Positives = 143/359 (39%), Gaps = 66/359 (18%)
Query: 7 KSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPS----TITFHQ 62
K++L+ G +GF+ H+ + P +I V D D S DPS F +
Sbjct: 9 KNILITGAAGFIASHVANRLIRNYPDYKIVVLDKL---DYCSDLKNLDPSFSSPNFKFVK 65
Query: 63 GDLTSPADVRKAIETSGATIVVHSASPMH-----GNSQEIYEKVNVKGTKNLLTVAKQC- 116
GD+ S V + T ++H A+ H GNS E + K N+ GT LL K
Sbjct: 66 GDIASDDLVNYLLITENIDTIMHFAAQTHVDNSFGNSFE-FTKNNIYGTHVLLEACKVTG 124
Query: 117 RVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLT 176
+++ ++ S+ V + +P + Y+ TKA A EM++ A
Sbjct: 125 QIRRFIHVSTDEVYGETDEDAAVGNHEASQLLPTNPYSATKAGA-EMLVMAYGRSYGLPV 183
Query: 177 IALRPAGIFGPGD--RQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQK 234
I R ++GP +++P +A G+ GD +N+ + Y +VA+A + K
Sbjct: 184 ITTRGNNVYGPNQFPEKMIPKFILLAMSGKPLPIHGDGSNVRSYLYCEDVAEAFEVVLHK 243
Query: 235 LLNPTTAALVSGETFFITNDTPTYFWALARTVWKADGHIDKRVIVLNRPMAIAAGYLSQF 294
GE + N ++RVI + R +
Sbjct: 244 -----------GEIGHVYN---------------VGTKRERRVIDVARDIC--------- 268
Query: 295 FSKLLGKEPGLT-------PFRVKIVCAYRYHNISKAKELLGYQPRVDIEEGIRRTLAW 346
KL GK+P + PF + RY + + LG+Q R + E+G+++T+ W
Sbjct: 269 --KLFGKDPESSIQFVENRPFNDQ-----RYFLDDQKLKKLGWQERTNWEDGLKKTMDW 320
>At1g12780 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 351
Score = 62.4 bits (150), Expect = 1e-09
Identities = 70/264 (26%), Positives = 112/264 (41%), Gaps = 34/264 (12%)
Query: 1 MSSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFD-----VRPLPDRISKQFTFDP 55
M SS +++L+ GG+GF+G H + Q LK ++ + D V DR+ + D
Sbjct: 1 MGSSVEQNILVTGGAGFIGTHTVVQL--LKDGFKVSIIDNFDNSVIEAVDRVRELVGPDL 58
Query: 56 S-TITFHQGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQE---IYEKVNVKGTKNLL 110
S + F+ GDL + D+ K V+H A G S E Y N+ GT NL
Sbjct: 59 SKKLDFNLGDLRNKGDIEKLFSKQRFDAVIHFAGLKAVGESVENPRRYFDNNLVGTINLY 118
Query: 111 TVAKQCRVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDP 170
+ K +V++SSA V + I ++ M+ Y TK EE+
Sbjct: 119 ETMAKYNCKMMVFSSSATVYGQPEKIPCMED---FELKAMNPYGRTKLFLEEIARDIQKA 175
Query: 171 ENDFLTIALR---PAGIFGPGD---------RQLVPGLRQVA-------KLGQSKFQIGD 211
E ++ I LR P G G L+P ++QVA + + D
Sbjct: 176 EPEWRIILLRYFNPVGAHESGSIGEDPKGIPNNLMPYIQQVAVGRLPELNVYGHDYPTED 235
Query: 212 NNNLFDWTYAGNVADAHVLAAQKL 235
+ + D+ + ++AD H+ A +KL
Sbjct: 236 GSAVRDYIHVMDLADGHIAALRKL 259
>Hs7657641 [G] KOG0747 Putative NAD+-dependent epimerases
Length = 350
Score = 62.0 bits (149), Expect = 1e-09
Identities = 60/235 (25%), Positives = 103/235 (43%), Gaps = 11/235 (4%)
Query: 7 KSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTF-DPSTITFHQGDL 65
K VL+ GG+GF+ H+I E P I D + T + F QGD+
Sbjct: 18 KRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDI 77
Query: 66 TSPADVRKAIETSGATIVVHSASPMHGNSQEI----YEKVNVKGTKNLLTVAKQCRVKAV 121
V+ ET IV+H A+ H + + + VNV GT L++ A + RV+
Sbjct: 78 CDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKF 137
Query: 122 VYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTIALRP 181
+Y S+ ++ G DE+ P+ P + Y +KA AE V S + + F + R
Sbjct: 138 IYVST-DEVYGGSLDKEFDES--SPKQPTNPYASSKAAAECFVQSYWE-QYKFPVVITRS 193
Query: 182 AGIFGPGD--RQLVPGLRQVAKLGQSKFQIGDNNNLFDWTYAGNVADAHVLAAQK 234
+ ++GP +++P + + + G ++ YA +V +A + +K
Sbjct: 194 SNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFLTVLKK 248
>At4g10960 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 351
Score = 60.8 bits (146), Expect = 3e-09
Identities = 67/257 (26%), Positives = 112/257 (43%), Gaps = 33/257 (12%)
Query: 7 KSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFD-----VRPLPDRISKQFTFDPSTITFH 61
++VL+ GG+G++G H + Q L + V D R+ K ++FH
Sbjct: 4 RNVLVSGGAGYIGSHTVLQL--LLGGYSVVVVDNLDNSSAVSLQRVKKLAAEHGERLSFH 61
Query: 62 QGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQE---IYEKVNVKGTKNLLTVAKQCR 117
Q DL + + K + V+H A G S E +Y N+ GT LL V Q
Sbjct: 62 QVDLRDRSALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNLVGTITLLEVMAQHG 121
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMV--LSANDPE---- 171
K +V++SSA V + +++ +E P ++ Y TK EE+ + +DPE
Sbjct: 122 CKNLVFSSSATVYGSPKEVPCTEE---FPISALNPYGRTKLFIEEICRDVYGSDPEWKII 178
Query: 172 --NDFLTIALRPAGIFGPGDR----QLVPGLRQVA-------KLGQSKFQIGDNNNLFDW 218
F + P+G G R L+P ++QVA + + + D + D+
Sbjct: 179 LLRYFNPVGAHPSGDIGEDPRGIPNNLMPFVQQVAVGRRPHLTVFGNDYNTKDGTGVRDY 238
Query: 219 TYAGNVADAHVLAAQKL 235
+ ++AD H+ A +KL
Sbjct: 239 IHVIDLADGHIAALRKL 255
>At1g63180 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 353
Score = 57.8 bits (138), Expect = 2e-08
Identities = 68/269 (25%), Positives = 117/269 (43%), Gaps = 38/269 (14%)
Query: 1 MSSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFD-----VRPLPDRISKQFTFDP 55
M SS +++L+ GG+GF+G H + Q L ++ + D V R+ + D
Sbjct: 1 MGSSVEQNILVTGGAGFIGTHTVVQL--LNQGFKVTIIDNLDNSVVEAVHRVRELVGPDL 58
Query: 56 ST-ITFHQGDLTSPADVRKAI--ETSGATIVVHSA-----SPMHGNSQEIYEKVNVKGTK 107
ST + F+ GDL + D+ K + + V+H A GN + ++ N+ GT
Sbjct: 59 STKLEFNLGDLRNKGDIEKLFSNQRNRFDAVIHFAGLKAVGESVGNPRRYFDN-NLVGTI 117
Query: 108 NLLTVAKQCRVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSA 167
NL + K +V++SSA ++ +I E + + M+ Y TK EE+
Sbjct: 118 NLYETMAKYNCKMMVFSSSA-TVYGQPEIVPCVEDFELQ--AMNPYGRTKLFLEEIARDI 174
Query: 168 NDPENDFLTIALR---PAGIFGPG---------DRQLVPGLRQVA-------KLGQSKFQ 208
+ E ++ I LR P G G L+P ++QVA + +
Sbjct: 175 HAAEPEWKIILLRYFNPVGAHESGRIGEDPKGIPNNLMPYIQQVAVGRLPELNVFGHDYP 234
Query: 209 IGDNNNLFDWTYAGNVADAHVLAAQKLLN 237
D + + D+ + ++AD HV A KL +
Sbjct: 235 TMDGSAVRDYIHVMDLADGHVAALNKLFS 263
>SPBPB2B2.12c [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 713
Score = 57.0 bits (136), Expect = 4e-08
Identities = 64/256 (25%), Positives = 109/256 (42%), Gaps = 34/256 (13%)
Query: 9 VLLIGGSGFLGLHLIQQFSELKPQPQIHVFD--VRPLPDRISKQFTFDPSTITFHQGDLT 66
+L+ GG+G++G H + + + ++ + D D +++ +I F + DL
Sbjct: 8 ILVTGGAGYIGSHTVIEL--INHGYKVIIVDNLCNSCYDAVARVEFIVRKSIKFFKLDLR 65
Query: 67 SPADVRKAIETSGATIVVHSAS-PMHGNSQEI---YEKVNVKGTKNLLTVAKQCRVKAVV 122
+ + +T V+H A+ G S ++ Y N+ GT LL V ++ RVK VV
Sbjct: 66 DKEGLAQIFDTFKIKGVIHFAALKAVGESMKLPLEYYDNNICGTITLLNVMREHRVKTVV 125
Query: 123 YTSSAGVIFNGQDIHNADETWPIPEV----PMDGYNETKAIAEEMVLSANDPEND----- 173
++SSA V D D PIPE P + Y +TK E ++ + +N
Sbjct: 126 FSSSATVY---GDATRFDNMIPIPESCPNDPTNPYGKTKYAIENIIKDLHTSDNTWRGAI 182
Query: 174 ---FLTIALRPAGIFGPG----DRQLVPGLRQVAKLGQSK-------FQIGDNNNLFDWT 219
F I P+G+ G L+P L QVA + K + D + D+
Sbjct: 183 LRYFNPIGAHPSGLLGEDPLGIPNNLLPFLAQVAIGRREKLLVFGDDYDSHDGTPIRDYI 242
Query: 220 YAGNVADAHVLAAQKL 235
+ ++A H+ A L
Sbjct: 243 HVVDLAKGHIAALNYL 258
>SPBC365.14c [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 355
Score = 55.5 bits (132), Expect = 1e-07
Identities = 65/255 (25%), Positives = 99/255 (38%), Gaps = 30/255 (11%)
Query: 8 SVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTS 67
+VL+ GG+G++G H E I + + + + FHQ DL
Sbjct: 8 TVLVTGGAGYIGSHTCVVLLEKGYDVVIVDNLCNSRVEAVHRIEKLTGKKVIFHQVDLLD 67
Query: 68 PADVRKAIETSGATIVVHSAS-PMHGNSQEI---YEKVNVKGTKNLLTVAKQCRVKAVVY 123
+ K + V+H A G S ++ Y K N+ GT NL+ K+ V+ V+
Sbjct: 68 EPALDKVFANQNISAVIHFAGLKAVGESVQVPLSYYKNNISGTINLIECMKKYNVRDFVF 127
Query: 124 TSSAGVIFNGQDIHNADETWPIPE-VPMDG---YNETKAIAEEMV---LSANDPENDFLT 176
+SSA V D T PIPE P +G Y TK E ++ N N L
Sbjct: 128 SSSATVY---GDPTRPGGTIPIPESCPREGTSPYGRTKLFIENIIEDETKVNKSLNAALL 184
Query: 177 IALRPAGIFGPGD---------RQLVPGLRQVA-------KLGQSKFQIGDNNNLFDWTY 220
P G G+ L+P + QVA + + D + D+ +
Sbjct: 185 RYFNPGGAHPSGELGEDPLGIPNNLLPYIAQVAVGRLDHLNVFGDDYPTSDGTPIRDYIH 244
Query: 221 AGNVADAHVLAAQKL 235
++A+AHV A L
Sbjct: 245 VCDLAEAHVAALDYL 259
>Hs4503891 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 348
Score = 55.5 bits (132), Expect = 1e-07
Identities = 61/258 (23%), Positives = 109/258 (41%), Gaps = 31/258 (12%)
Query: 7 KSVLLIGGSGFLGLHLIQQFSELKPQPQI-----HVF-DVRPLPDRISKQFTFDPSTITF 60
+ VL+ GG+G++G H + + E P + + F LP+ + + ++ F
Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
Query: 61 HQGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQEI---YEKVNVKGTKNLLTVAKQC 116
+ D+ +++ + V+H A G S + Y +VN+ GT LL + K
Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
Query: 117 RVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLT 176
VK +V++SSA V N Q + DE P + Y ++K EEM+ + +
Sbjct: 123 GVKNLVFSSSATVYGNPQYL-PLDEAHPTGGC-TNPYGKSKFFIEEMIRDLCQADKTWNV 180
Query: 177 IALR---PAGIFGPG----DRQLVP------------GLRQVAKLGQSKFQIGDNNNLFD 217
+ LR P G G D Q +P G R+ + + + D + D
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
Query: 218 WTYAGNVADAHVLAAQKL 235
+ + ++A H+ A +KL
Sbjct: 241 YIHVVDLAKGHIAALRKL 258
>Hs18601393 [IE] KOG1430 C-3 sterol dehydrogenase/3-beta-hydroxysteroid
dehydrogenase and related dehydrogenases
Length = 398
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/216 (25%), Positives = 98/216 (44%), Gaps = 14/216 (6%)
Query: 18 LGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTF--DPSTITFHQGDLTSPADVRKAI 75
+G +I+ E K +I D P+ + K+F+ + + +T +GD+ + +++A
Sbjct: 9 MGSSIIRLLVEEKELKEIRALDKAFRPE-LRKEFSELQNKTKLTVLEGDILDESCLKRAC 67
Query: 76 ETSGATIVVHSASPMHG-NSQEIYEKVNVKGTKNLLTVAKQCRVKAVVYTSS---AGVIF 131
+ I S + G +E +NVK T+ LL Q V +YTS+ AG
Sbjct: 68 QDMSVIIHTTSIIDIIGVTHRESIMNINVKRTQLLLEACVQATVPVFIYTSTPEVAGPNS 127
Query: 132 NGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSAN----DPENDFLTIALRPAGIFGP 187
+ I N+ E P+ Y +K +AE+ VL+AN T ALRP I+G
Sbjct: 128 YKEIIQNSHEEEPLENTWYAPYPHSKKLAEKAVLAANGWTLKNGGTLYTCALRPMFIYGE 187
Query: 188 GDRQLVPGLRQVAK---LGQSKFQIGDNNNLFDWTY 220
G L G+ + + S ++ +N++F ++Y
Sbjct: 188 GSPILSAGINEALNNHGILSSFSKVTLSNSVFTFSY 223
>Hs14725159 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 348
Score = 55.5 bits (132), Expect = 1e-07
Identities = 61/258 (23%), Positives = 109/258 (41%), Gaps = 31/258 (12%)
Query: 7 KSVLLIGGSGFLGLHLIQQFSELKPQPQI-----HVF-DVRPLPDRISKQFTFDPSTITF 60
+ VL+ GG+G++G H + + E P + + F LP+ + + ++ F
Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
Query: 61 HQGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQEI---YEKVNVKGTKNLLTVAKQC 116
+ D+ +++ + V+H A G S + Y +VN+ GT LL + K
Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
Query: 117 RVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLT 176
VK +V++SSA V N Q + DE P + Y ++K EEM+ + +
Sbjct: 123 GVKNLVFSSSATVYGNPQYL-PLDEAHPTGGC-TNPYGKSKFFIEEMIRDLCQADKTWNA 180
Query: 177 IALR---PAGIFGPG----DRQLVP------------GLRQVAKLGQSKFQIGDNNNLFD 217
+ LR P G G D Q +P G R+ + + + D + D
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
Query: 218 WTYAGNVADAHVLAAQKL 235
+ + ++A H+ A +KL
Sbjct: 241 YIHVVDLAKGHIAALRKL 258
>YDR541c [V] KOG1502 Flavonol reductase/cinnamoyl-CoA reductase
Length = 344
Score = 53.5 bits (127), Expect = 4e-07
Identities = 55/205 (26%), Positives = 93/205 (44%), Gaps = 29/205 (14%)
Query: 8 SVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFHQGDLTS 67
+VL+ G SGF+ LH++ Q + + I ++ +QF +P+ D++
Sbjct: 4 TVLVSGASGFIALHILSQLLK-QDYKVIGTVRSHEKEAKLLRQFQHNPNLTLEIVPDISH 62
Query: 68 PADVRKAIETSGATI--VVHSASPMHGNSQEIYEK----VNVKGTKNLLTVAKQC---RV 118
P K ++ G I V+H+ASP H ++ E YEK ++GTKN+L K+ V
Sbjct: 63 PNAFDKVLQKRGREIRYVLHTASPFHYDTTE-YEKDLLIPALEGTKNILNSIKKYAADTV 121
Query: 119 KAVVYTSSA------------GVIFNGQDIHNADETWPIPEVP-MDGYNETKAIAEEMV- 164
+ VV TSS V+F + + A TW ++ ++ Y +K AE+
Sbjct: 122 ERVVVTSSCTAIITLAKMDDPSVVFTEESWNEA--TWESCQIDGINAYFASKKFAEKAAW 179
Query: 165 --LSANDPENDFLTIALRPAGIFGP 187
N+ F + P+ +FGP
Sbjct: 180 EFTKENEDHIKFKLTTVNPSLLFGP 204
>YBR019c_1 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 363
Score = 53.1 bits (126), Expect = 6e-07
Identities = 68/265 (25%), Positives = 104/265 (38%), Gaps = 37/265 (13%)
Query: 2 SSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPSTITFH 61
S S K VL+ GG+G++G H + + E + D +++ I F+
Sbjct: 7 SESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFY 66
Query: 62 QGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQEI---YEKVNVKGTKNLLTVAKQCR 117
+ DL + K + V+H A G S +I Y N+ GT LL + +Q
Sbjct: 67 EVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQYN 126
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEV----PMDGYNETKAIAEEMVLSANDPEND 173
V V++SSA V + N PIPE P + Y TK E ++ ND N
Sbjct: 127 VSKFVFSSSATVYGDATRFPN---MIPIPEECPLGPTNPYGHTKYAIENIL---NDLYNS 180
Query: 174 ------------FLTIALRPAGIFGPG----DRQLVPGLRQVAKLGQSKFQI-------G 210
F I P+G+ G L+P + QVA + K I
Sbjct: 181 DKKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSR 240
Query: 211 DNNNLFDWTYAGNVADAHVLAAQKL 235
D + D+ + ++A H+ A Q L
Sbjct: 241 DGTPIRDYIHVVDLAKGHIAALQYL 265
>At1g30620 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 412
Score = 52.8 bits (125), Expect = 8e-07
Identities = 64/263 (24%), Positives = 110/263 (41%), Gaps = 44/263 (16%)
Query: 6 VKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPD----RISKQFTFDPSTITFH 61
V VL+ GG+G++G H + LK ++ + D + RI ++ +P + F
Sbjct: 63 VTHVLVTGGAGYIGSHAALRL--LKESYRVTIVDNLSRGNLAAVRILQELFPEPGRLQFI 120
Query: 62 QGDLTSPADVRKAIETSGATIVVHSASPMH-GNSQEIYEKVNVKGTKNLLTVAKQCR--- 117
DL V K + V+H A+ + G S + K T N L V +
Sbjct: 121 YADLGDAKAVNKIFTENAFDAVMHFAAVAYVGESTQFPLKYYHNITSNTLVVLETMAAHG 180
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLS----------- 166
VK ++Y+S+ + +ET P+VP++ Y + K +AE+++L
Sbjct: 181 VKTLIYSSTCATYGEPDIMPITEET---PQVPINPYGKAKKMAEDIILDFSKNSDMAVMI 237
Query: 167 -------ANDPENDFLTIALRP--------AGIFGPGDRQLVPGLRQVAKLGQSKFQIGD 211
+DPE L A RP +G R ++PGL ++ + ++ D
Sbjct: 238 LRYFNVIGSDPEGR-LGEAPRPELREHGRISGACFDAARGIMPGL----QIKGTDYKTAD 292
Query: 212 NNNLFDWTYAGNVADAHVLAAQK 234
+ D+ ++ DAHV A QK
Sbjct: 293 GTCVRDYIDVTDLVDAHVKALQK 315
>At5g44480 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 436
Score = 51.2 bits (121), Expect = 2e-06
Identities = 59/259 (22%), Positives = 108/259 (40%), Gaps = 36/259 (13%)
Query: 6 VKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPD----RISKQFTFDPSTITFH 61
V VL+ GG+G++G H + L+ ++ + D + + +Q + F
Sbjct: 94 VTHVLVTGGAGYIGSHAALRL--LRDSYRVTIVDNLSRGNLGAVKTLQQLFPQTGRLQFI 151
Query: 62 QGDLTSPADVRKAIETSGATIVVHSASPMHGNSQEIYE-KVNVKGTKNLLTVAKQC---R 117
DL P V K + V+H A+ + +Y K T N L V + +
Sbjct: 152 YADLGDPLAVEKIFSENAFDAVMHFAAVAYVGESTLYPLKYYHNITSNTLGVLEAMARHK 211
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLSANDPENDFLTI 177
VK ++Y+S+ + + ++T P+VP++ Y + K +AE+M+L + +D +
Sbjct: 212 VKKLIYSSTCATYGEPEKMPITEDT---PQVPINPYGKAKKMAEDMILDFS-KNSDMAVM 267
Query: 178 ALRPAGIFG--PGDR---QLVPGLRQVAKLGQSKF-----------------QIGDNNNL 215
LR + G PG R P LR+ ++ + F + D +
Sbjct: 268 ILRYFNVIGSDPGGRLGEAPRPELREQGRISGACFDAARGFIPGLQVKGTDYKTSDGTCI 327
Query: 216 FDWTYAGNVADAHVLAAQK 234
D+ ++ DAHV A +K
Sbjct: 328 RDYIDVTDLVDAHVKALEK 346
>At1g64440 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 348
Score = 50.8 bits (120), Expect = 3e-06
Identities = 65/258 (25%), Positives = 104/258 (40%), Gaps = 33/258 (12%)
Query: 6 VKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPDRISKQFTFDPS-----TITF 60
V ++L+ GG+G++G H + Q L V D +S Q D + +T
Sbjct: 2 VGNILVTGGAGYIGSHTVLQL--LLGGYNTVVIDNLDNSSLVSIQRVKDLAGDHGQNLTV 59
Query: 61 HQGDLTSPADVRKAIETSGATIVVHSAS-PMHGNSQE---IYEKVNVKGTKNLLTVAKQC 116
HQ DL + K + V+H A G S +Y N+ T LL V
Sbjct: 60 HQVDLRDKPALEKVFSETKFDAVMHFAGLKAVGESVAKPLLYYNNNLIATITLLEVMAAH 119
Query: 117 RVKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMV--LSANDPE--- 171
K +V++SSA V +++ +E+ P M Y TK E++ + DPE
Sbjct: 120 GCKKLVFSSSATVYGWPKEVPCTEES---PLSGMSPYGRTKLFIEDICRDVQRGDPEWRI 176
Query: 172 ---NDFLTIALRPAGIFG-----------PGDRQLVPGLRQVAKLGQSKFQIGDNNNLFD 217
F + P+G G P +Q+V G K+ + + D + D
Sbjct: 177 IMLRYFNPVGAHPSGRIGEDPCGTPNNLMPYVQQVVVGRLPNLKIYGTDYTTKDGTGVRD 236
Query: 218 WTYAGNVADAHVLAAQKL 235
+ + ++AD H+ A QKL
Sbjct: 237 YIHVVDLADGHICALQKL 254
>7291983 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 350
Score = 50.8 bits (120), Expect = 3e-06
Identities = 62/264 (23%), Positives = 106/264 (39%), Gaps = 41/264 (15%)
Query: 8 SVLLIGGSGFLGLHLIQQ-----FSELKPQPQIHVFDV-RPLPDRISKQFTFDPSTITFH 61
+VL+ GG+G++G H + + ++ + + + LP+ +S+ + F+
Sbjct: 5 TVLVTGGAGYIGSHTVLEMLNAGYNVICVDNLCNAYSSGAKLPEALSRVQEITGKKVNFY 64
Query: 62 QGDLTSPADVRKAIETSGATIVVH-SASPMHGNSQEI---YEKVNVKGTKNLLTVAKQCR 117
+ D+T VR + +V H +A G S I Y N+ GT LL
Sbjct: 65 RVDITDREQVRSVFQEHKIDMVAHFAALKAVGESCRIPLQYYHNNMTGTNVLLEAMADNN 124
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDG-----YNETKAIAEEMVLSANDPEN 172
V VY+SSA ++ + P+ E G Y +TK EE++ +
Sbjct: 125 VFKFVYSSSA-------TVYGEPKFLPVTEEHPTGNCTSPYGKTKYFTEEILKDLCKSDK 177
Query: 173 DFLTIALR---PAGIFGPG---------DRQLVPGLRQVA-------KLGQSKFQIGDNN 213
+ ++LR P G G L+P + QVA + S F D
Sbjct: 178 RWAVVSLRYFNPVGAHISGRIGEDPNGEPNNLMPYIAQVAVGRRPSLSVYGSDFPTHDGT 237
Query: 214 NLFDWTYAGNVADAHVLAAQKLLN 237
+ D+ + ++A+ HV A KL N
Sbjct: 238 GVRDYIHIVDLAEGHVKALDKLRN 261
>At2g34850 [M] KOG1371 UDP-glucose 4-epimerase/UDP-sulfoquinovose synthase
Length = 375
Score = 49.7 bits (117), Expect = 6e-06
Identities = 61/263 (23%), Positives = 109/263 (41%), Gaps = 46/263 (17%)
Query: 2 SSSDVKSVLLIGGSGFLGLHLIQQFSELKPQPQIHVFDVRPLPD----RISKQFTFDPST 57
S V VL+ GG+G++G H + LK ++ + D + +I +Q +P
Sbjct: 33 SEPGVTHVLVTGGAGYIGSHAALRL--LKDSYRVTIVDNLSRGNLGAVKILQQLFPEPGK 90
Query: 58 ITFHQGDLTSPADVRKAIETSGATIVVHSASPMHGNSQEIYEKVNVKGTKNLLTVAKQCR 117
+ F DL V K + V+H A+ + Y + L T+A
Sbjct: 91 LQFIYADLGDANAVNKIFSENAFDAVMHFAAVAY-----YYHNITSNTLVVLETMAAH-G 144
Query: 118 VKAVVYTSSAGVIFNGQDIHNADETWPIPEVPMDGYNETKAIAEEMVLS----------- 166
VK ++Y+S+ + + +ET P+VP++ Y + K +AE+++L
Sbjct: 145 VKTLIYSSTCATYGEPEKMPITEET---PQVPINPYGKAKKMAEDIILDFSKNSIMAVMI 201
Query: 167 -------ANDPENDFLTIALRP--------AGIFGPGDRQLVPGLRQVAKLGQSKFQIGD 211
+DPE L A RP +G R ++PGL ++ + ++ D
Sbjct: 202 LRYFNVIGSDPEGR-LGEAPRPELSEHGRISGACFDAARGIIPGL----QIKGTDYKTVD 256
Query: 212 NNNLFDWTYAGNVADAHVLAAQK 234
+ D+ ++ DAHV A +K
Sbjct: 257 GTCVRDYIDVTDLVDAHVKALEK 279
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,357,350
Number of Sequences: 60738
Number of extensions: 926859
Number of successful extensions: 2070
Number of sequences better than 1.0e-05: 38
Number of HSP's better than 0.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1985
Number of HSP's gapped (non-prelim): 47
length of query: 351
length of database: 30,389,216
effective HSP length: 107
effective length of query: 244
effective length of database: 23,890,250
effective search space: 5829221000
effective search space used: 5829221000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)