ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4655 good K KOG1831 Transcription Negative regulator of transcription
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4655 1646511 1652930 2140
(2140 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YCR093w [K] KOG1831 Negative regulator of transcription 1061 0.0
SPAC20G8.06 [K] KOG1831 Negative regulator of transcription 284 1e-75
Hs22067248 [K] KOG1831 Negative regulator of transcription 254 1e-66
At1g02080 [K] KOG1831 Negative regulator of transcription 230 2e-59
7303881 [K] KOG1831 Negative regulator of transcription 201 1e-50
CE01337 [K] KOG1831 Negative regulator of transcription 193 3e-48
Hs7706214 [K] KOG1831 Negative regulator of transcription 131 1e-29
ECU11g1370 [K] KOG1831 Negative regulator of transcription 56 6e-07
>YCR093w [K] KOG1831 Negative regulator of transcription
Length = 2108
Score = 1061 bits (2745), Expect = 0.0
Identities = 563/1298 (43%), Positives = 838/1298 (64%), Gaps = 39/1298 (3%)
Query: 12 DLNSITYIPTFPEPFERDNSHTTASFVSIQIRLLVASVTEENFLDTEHQIYYLLQRGSFS 71
DLN+ + + T E A V QI LL ++ +NF E +I ++L R S
Sbjct: 8 DLNTASNLETSKEK-------QAAQIVIAQISLLFTTLNNDNFESVEREIRHILDRSSVD 60
Query: 72 VYISYWKLLIQLFVNEFEAQQQKRDLNLPFRFDFS-NLVHRLLYNLAQELITRTPDTIEK 130
+YI W+ L+ L RD+ +F NL+HRLL A++L ++ D IE
Sbjct: 61 IYIKVWERLLTL---------SSRDILQAGKFLLQENLLHRLLLEFAKDLPKKSTDLIEL 111
Query: 131 VKELALPLSGKYPIRPLFLSFLNK--DNESDSAIIEALNPEVHPIFTTLKDLHRTNMSVS 188
+KE + LS D ++ IIE+L+ + + D M+ +
Sbjct: 112 LKERTFNNQEFQKQTGITLSLFIDLFDKSANKDIIESLDRS-----SQINDFKTIKMNHT 166
Query: 189 NITQNLFAVENKPNFLTMLSEFLKPLQGETLNDWIALILSEILAPGSQT-SNQPSQPWIV 247
N +N F + L + L L+GE+LND +AL+LSEIL+PGSQ N P++ W+
Sbjct: 167 NYLRNFFLQTTPETLESNLRDLLHSLEGESLNDLLALLLSEILSPGSQNLQNDPTRSWLT 226
Query: 248 QVPNVDVREVIEATEMGTKVNGIIKSLGTNNVNWNRVFNLMSTKFFLNKPVNATLSSLNY 307
V++AT G + I SL N +NWNRVFNLMSTK+FL+ P+ T +SL+
Sbjct: 227 PPM------VLDATNRGNVIARSISSLQANQINWNRVFNLMSTKYFLSAPLMPTTASLSC 280
Query: 308 LFCILNSGPLVDQFFACDWSLYFKLRLSFLMYQWNYNSECLDLSSLPNIKKINKSIPLTK 367
LF L+ GP++D+FF+CDW + FKL L+ +++W+ + C DL + +K++++IP TK
Sbjct: 281 LFAALHDGPVIDEFFSCDWKVIFKLDLAIQLHKWSVQNGCFDLLNAEGTRKVSETIPNTK 340
Query: 368 KSQLSLISVGKLNIELFLSRDEISKNPLFSSFHASFSEAYNNVPEYLAAVLISESKYFSL 427
+S L L+S+ LN+ELFL R+E+S P+ + F F E +N PEYL L+ E K F L
Sbjct: 341 QSLLYLLSIASLNLELFLQREELSDGPMLAYFQECFFEDFNYAPEYLILALVKEMKRFVL 400
Query: 428 LVDNKSIIDELLISLVIKTYENNVIAFKELLKLVSKQ-KVIEVSRGIIASQNAQTINLVQ 486
L++N+++IDE+LI+L+I+ + + +FK+++ ++ K+++ ++ II S +A N ++
Sbjct: 401 LIENRTVIDEILITLLIQVHNKSPSSFKDVISTITDDSKIVDAAKIIINSDDAPIANFLK 460
Query: 487 ALHDLGILDEVFEKLPIRDSLKLSPTAMHLGYLKFSEYIERNITLKTFVPTLDFIEAQTN 546
+L D G LD V KLP ++ K+ P A +G+ F +++ ++ L+ +E QT
Sbjct: 461 SLLDTGRLDTVINKLPFNEAFKILPCARQIGWEGFDTFLKTKVSPSNVDVVLESLEVQTK 520
Query: 547 IDELDPALKSVKLLNLHSLHSLIYRTANLKLSADERVALNNVIFKALISFPRLINYGYGH 606
+ + + +S+K +L + HSLI L + ++ F LI+FPRLIN+G+GH
Sbjct: 521 MTDTNTPFRSLKTFDLFAFHSLIEVLNKCPLDVLQLQRFESLEFSLLIAFPRLINFGFGH 580
Query: 607 DDAIVANGDHAPIPQDVEKKMQTYLQKMYNKEMAIKDIVDILRKLRDSDDSNDQDIFCCI 666
D+AI+ANGD A I D+EK+MQ YLQKMY+ E+AIKD++++LR+LRDSD DQ++F CI
Sbjct: 581 DEAILANGDIAGINNDIEKEMQNYLQKMYSGELAIKDVIELLRRLRDSDLPRDQEVFTCI 640
Query: 667 IHAVIAETTFFKEYPLEALATTSVLFGSMILFDLLRGFVLDVAFQIIYTFASESPDSKMF 726
HAVIAE+TFF++YPL+ALATTSVLFGSMILF LLRGFVLDVAF+II FA E P+SKMF
Sbjct: 641 THAVIAESTFFQDYPLDALATTSVLFGSMILFQLLRGFVLDVAFRIIMRFAKEPPESKMF 700
Query: 727 KFAVQALYAFRMRLNEYSPFCKRLLDEIXXXXXXXXXXXXXXESAANPNVSIPEQKAPA- 785
KFAVQA+YAFR+RL EY +CK LL ++ E+A N E+ P
Sbjct: 701 KFAVQAIYAFRIRLAEYPQYCKDLLRDVPALKSQAQVYQSIVEAATLANAP-KERSRPVQ 759
Query: 786 -LVELNYFNINEVISPVTQEVPPREVTEAILFNVNNITMSNFDTKIVELKALLEEKYYQW 844
++ L +F ++EV + QE P++V E +LF +NN+T++N + K+ ELK L Y+ W
Sbjct: 760 EMIPLKFFAVDEVSCQINQEGAPKDVVEKVLFVLNNVTLANLNNKVDELKKSLTPNYFSW 819
Query: 845 FSNYLVNQRSKTEPNYHPLYAKMLKIIDSKTLHAYMLNFTYKQLFIMLSTKELGQTEKTH 904
FS YLV QR+KTEPNYH LY+K++ + S LH +M+N T +QLF++LSTK+ +K H
Sbjct: 820 FSTYLVTQRAKTEPNYHDLYSKVIVAMGSGLLHQFMVNVTLRQLFVLLSTKDEQAIDKKH 879
Query: 905 MKNLSSWLGSITLSLDIPIKHKHIAFRELLLDAHKNDRLTVVIPFVARIIMQSKDSKVFC 964
+KNL+SWLG ITL+L+ PIKHK+IAFRE+L++A+K +RL +V+PFV +I+ ++ +SK+F
Sbjct: 880 LKNLASWLGCITLALNKPIKHKNIAFREMLIEAYKENRLEIVVPFVTKILQRASESKIFK 939
Query: 965 PPNPWTMGILKLLLELNQKTDWPLSLSFEVEVLFKHLNLQFDDISPSNYLDIPDAAEYLS 1024
PPNPWT+GILKLL+ELN+K +W LSL+FEVEVL K NL + PSN+++ P+ E LS
Sbjct: 940 PPNPWTVGILKLLIELNEKANWKLSLTFEVEVLLKSFNLTTKSLKPSNFINTPEVIETLS 999
Query: 1025 GNLRALSVEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIISNGYGN--- 1081
G L ++++E+ I +N +
Sbjct: 1000 GALGSITLEQQQTEQQRQIILMQQHQQQMLIYQQRQQQQQQRQQQQQHHISANTIADQQA 1059
Query: 1082 AMNDQASLETSDAPHSSLVGNSVFVTHPDLKRLFQMAVSKSVREILIPAVEKAANMAVQS 1141
A + S+ + D P ++L+G+++FVTHPDLKR+FQMA++KSVREIL+ VEK++ +AV +
Sbjct: 1060 AFGGEGSI-SHDNPFNNLLGSTIFVTHPDLKRVFQMALAKSVREILLEVVEKSSGIAVVT 1118
Query: 1142 TVNIVLKDFATEVDEQKLKTAAINMVQYLAQNVAHSISVPLLKDTIRNTTQSLTPNLINM 1201
T I+LKDFATEVDE KLKTAAI MV++LAQ++A + S+ LK+ IR+T QSL PNL+++
Sbjct: 1119 TTKIILKDFATEVDESKLKTAAIIMVRHLAQSLARATSIEPLKEGIRSTMQSLAPNLMSL 1178
Query: 1202 TNSPIAELNTAIDDNIAIAVSPIEKAAVERAIQEVNEKLVQAVAVRRYHLERRSDQPFVA 1261
++SP EL+TAI++NI IA+ IEKA+++++ Q++ ++L+QA+A+RRYH ERR+DQPF+
Sbjct: 1179 SSSPAEELDTAINENIGIALVLIEKASMDKSTQDLADQLMQAIAIRRYHKERRADQPFIT 1238
Query: 1262 QNINRFSLNLPDPLGLKPTGVTREQFSLYEQFPASMPS 1299
QN N +SL+LP+PLGLK TGVT +QF +YE+F ++P+
Sbjct: 1239 QNTNPYSLSLPEPLGLKNTGVTPQQFRVYEEFGKNIPN 1276
Score = 805 bits (2080), Expect = 0.0
Identities = 396/731 (54%), Positives = 530/731 (72%), Gaps = 5/731 (0%)
Query: 1409 ISAAHSELEQNHRVLLQLMDTLVSQIKDYSEDVEF-NLQNDSTIKNTIVEILSFISRSNQ 1467
I+A S+LEQN RVL+ LMD LVSQIK+ + L + + IK I +IL+FI++S Q
Sbjct: 1353 IAAVQSDLEQNQRVLVHLMDILVSQIKENATKNNLAELGDQNQIKTIIFQILTFIAKSAQ 1412
Query: 1468 KDQLSLKVSQAVVNSLFGSNESKLCRDVXXXXXXXXXXXXIVARKDVVWWLVYALDPRKF 1527
KDQL+LKVSQAVVNSLF ++ES LCR+V +VARKDVVWWLVYALD RKF
Sbjct: 1413 KDQLALKVSQAVVNSLFATSESPLCREVLSLLLEKLCSLSLVARKDVVWWLVYALDSRKF 1472
Query: 1528 NVPVVRSLLEVNLINIAEFDAVLVTAMKNGMAGATEFSMNLIRDTVMADSPILMRLDFIR 1587
NVPV+RSLLEVNLI+ E D VLVTAMKN M +TEF+M LI++TV++D PILMR+DFI+
Sbjct: 1473 NVPVIRSLLEVNLIDATELDNVLVTAMKNKMENSTEFAMKLIQNTVLSDDPILMRMDFIK 1532
Query: 1588 ILGYLRTINTPEIKAFLEEYEQCRAVPVSKTTSITKVERYYLVFTEWVKLQQRVETDDVV 1647
L +L + +K F++E+E + +PV K T T+ E+ YLVFTEWVKL QRVE +DV+
Sbjct: 1533 TLEHLASSEDENVKKFIKEFEDTKIMPVRKGTKTTRTEKLYLVFTEWVKLLQRVENNDVI 1592
Query: 1648 NIVFIRQLFEKGVIDSKEKVIEFIKAALELSVNSFKQSDPTGEVFTSIDALSRLITSLLV 1707
VFI+QL EKGVI + ++ F+K++LELSV+SFK+SDPT EVF +IDAL LI LL+
Sbjct: 1593 TTVFIKQLVEKGVISDTDNLLTFVKSSLELSVSSFKESDPTDEVFIAIDALGSLIIKLLI 1652
Query: 1708 VQELNVEERKEYLNLLLSVVTLVFAKDHQTNMTSFNERPYFRLYSSLLSDWDKLRDHHFI 1767
+Q + R++Y+N + SV+ LVFAKDH T+FNERPYFRL+S++L +W +R H+F+
Sbjct: 1653 LQGFKDDTRRDYINAIFSVIVLVFAKDHSQEGTTFNERPYFRLFSNILYEWATIRTHNFV 1712
Query: 1768 RVSDSVVRKSLIEFDQYFFDIFASFLHSYQPIAFPGFSFAWITLISHRMFLPKVLRSKEL 1827
R+SDS R+ LIEFD F++ F+ +LH+ QP AFPGFSFAW+TL+SHRM LP +LR
Sbjct: 1713 RISDSSTRQELIEFDSVFYNTFSGYLHALQPFAFPGFSFAWVTLLSHRMLLPIMLRLPNK 1772
Query: 1828 YGWDKLVLLLIDLMKFLSQYIKKDNVPDSISVIYKGALRIFLGISNDVPEFLIQNHYKLV 1887
GW+KL+LL+IDL KFL QY K V D++SV+YKG LR+ LGISND+P FLI+NHY+L+
Sbjct: 1773 IGWEKLMLLIIDLFKFLDQYTSKHAVSDAVSVVYKGTLRVILGISNDMPSFLIENHYELM 1832
Query: 1888 KNVPPTCIQLRNIILSAIPKKMMIPDPFVSEITEDN---CKDIPQVFYDPSQDLKSLKKP 1944
N+PPT QL+N+ILSAIPK M +P+P+ ++ ++ CK++P+VF+DP DL SLKKP
Sbjct: 1833 NNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDIPACKELPEVFFDPVIDLHSLKKP 1892
Query: 1945 IINYLRIPSSSLLRTICGGMFRTELEYENGIGYDENNVDVNLIHAIVTHVAVEVGLEVEK 2004
+ NYLRIPS+SLLRTI +++ + + G+GYD +VD LI AIV HV +E G+E ++
Sbjct: 1893 VDNYLRIPSNSLLRTILSAIYKDTYDIKKGVGYDFLSVDSKLIRAIVLHVGIEAGIEYKR 1952
Query: 2005 ASKNAVFNVKSSYYTLLFGLLSDGNDEVKFHIIQAMVNQLRYPNVHTHWFNFALKLMFQS 2064
S NAVFN KSSYYTLLF L+ +G+ E+K+ II ++V QLRYPN+HT+WF+F L MF+S
Sbjct: 1953 TSSNAVFNTKSSYYTLLFNLIQNGSIEMKYQIILSIVEQLRYPNIHTYWFSFVLMNMFKS 2012
Query: 2065 DQWPDDQLSTXXXXXXXXXXXXXXVNKPHPWGVVVTFMDLLKLEGTKMIEKPFINDIPEI 2124
D+W D +L VNKPH WGV V F L+ +++ PF+ +PEI
Sbjct: 2013 DEWNDQKLEV-QEIILRNFLKRIIVNKPHTWGVSVFFTQLINNNDINLLDLPFVQSVPEI 2071
Query: 2125 HAIMKNLQKYA 2135
I++ L KY+
Sbjct: 2072 KLILQQLVKYS 2082
>SPAC20G8.06 [K] KOG1831 Negative regulator of transcription
Length = 2100
Score = 284 bits (727), Expect = 1e-75
Identities = 194/634 (30%), Positives = 326/634 (50%), Gaps = 52/634 (8%)
Query: 406 AYNNVPEYLAAVLISESKYFSLLVDNKSIIDELLISLVIKTYENNVIAFKELLKLVSKQK 465
A+N V E LA S+ +FS ++K + + +T + AF L L
Sbjct: 461 AWNPVQESLAFQWCSD--FFSNFKEHKFVFVR-----IERTNPQFLFAFLRSLWLKDSSS 513
Query: 466 VIEVSRGIIASQNAQTINLVQALHDLGILDEVFEKLPIRDSLKLSPTAMHLGYLKFSEYI 525
V +V II + I +Q P R +L+++ A L F +++
Sbjct: 514 VNQVVEFIIENDFTSHIGNIQ---------------PNRFALEIAALAAARKALSFQDWL 558
Query: 526 ERNIT-------LKTF-VPTLDFIEAQTNIDELDPALKSVKL-LNLHSLHSLIYRTA-NL 575
++ + L F V LDF+ ++ + + + K + L++ +++ L+ N+
Sbjct: 559 DKKMLEFEDADGLNVFLVEVLDFLMSRAALQKNESEQKEESVVLSIDTVNVLLTTLMDNV 618
Query: 576 KLSADERVALNNVIFKALISFPRLINYGYGHDDAIVANGDHAPIPQDVEKKMQTYLQKMY 635
+S + + +V L +PRL + G+ D ++A DVE ++++Y Q +Y
Sbjct: 619 SISEEVSEHIKDVQILCLQVYPRLFSLGHDRDSIVIATNTTNSFSPDVESEVESYFQALY 678
Query: 636 NKEMAIKDIVDILRKLRDSDDSNDQDIFCCIIHAVIAETTFFKEYPLEALATTSVLFGSM 695
+ ++I IV L+ + S++ D D+F C+ H++ E FF +YPLEALA T+VLFGS+
Sbjct: 679 ERRISIGKIVLTLQNFKKSENPRDLDLFACLQHSLFDEYRFFPDYPLEALALTAVLFGSL 738
Query: 696 ILFDLLRGFVLDVAFQIIYTFASESPDSKMFKFAVQALYAFRMRLNEYSPFCKRLLDEIX 755
I F+LL L VA + +Y DSKMF+F +QAL F+ +L +Y +C +L
Sbjct: 739 IQFELLSFVPLGVALRYVYQALLMPTDSKMFRFGMQALVQFQEKLPKYINYCNLILGIPS 798
Query: 756 XXXXXXXXXXXXXES-AANPNVSIPEQK-----------APALVELNYFNINEVISPVTQ 803
E A+N N + + K +P E + +I+ + P+
Sbjct: 799 LQLVRPDIYDSIREMIASNENTEVEKDKLDSFSALANPASPKAPEYTFVSIH--VPPLNV 856
Query: 804 EVPPREVTEA----ILFNVNNITMSNFDTKIVELKALLEEKYYQWFSNYLVNQRSKTEPN 859
E+ E+ ILF +NN++ NF+ K+ ++K L Y WFS+Y+V QR E N
Sbjct: 857 PNAEGEIEESVCDNILFAINNLSQLNFNEKLKDVKDNLTPAYLPWFSHYIVTQRVSREAN 916
Query: 860 YHPLYAKMLKIIDSKTLHAYMLNFTYKQLFIML--STKELGQTEKTHMKNLSSWLGSITL 917
+ LY K L+ + S L+ + T + + ++ + + L +EKT++KNL SWLGSITL
Sbjct: 917 FLSLYGKFLEELKSSDLYKIVFRDTLQAILDIMNNNAETLSPSEKTNLKNLGSWLGSITL 976
Query: 918 SLDIPIKHKHIAFRELLLDAHKNDRLTVVIPFVARIIMQSKDSKVFCPPNPWTMGILKLL 977
+ PI ++F++LLL+ + R+ V+PFV +++ ++ S +F PPNPW MGILKLL
Sbjct: 977 LRNKPITTLQVSFKDLLLEGIDSGRIDRVLPFVCKVLEKASSSVIFKPPNPWLMGILKLL 1036
Query: 978 LELNQKTDWPLSLSFEVEVLFKHLNLQFDDISPS 1011
+EL Q D+ L+L FE+E+L +LN++ D+I PS
Sbjct: 1037 VELYQFADFRLNLKFEIELLLNNLNVKMDNIEPS 1070
Score = 206 bits (524), Expect = 3e-52
Identities = 156/645 (24%), Positives = 291/645 (44%), Gaps = 51/645 (7%)
Query: 1520 YALDPRKFNVPVVRSLLEVNLINIAEFDAVLVTAMKN--GMAGATEFSMNLIRDTVMADS 1577
++ D K N+P++ SL+ ++ E D + +++ G T+F++ L+R V ++
Sbjct: 1467 FSNDLEKLNLPIILSLIRFGILTSGEVDYHVARGVRSEQGSGPVTDFAIELLRTAVGGEN 1526
Query: 1578 PILMRLDFIRILGYLRTIN---TPEIKAFLEEYEQCRAVPVSKTTSITKV--------ER 1626
P+ + +F+ + L I+ + E K E+ + VS + I ++
Sbjct: 1527 PMALPGNFVNSITSLYEISESFSGETKQAYEQLVETMNKSVSPASEILSDLDNKQQLNDQ 1586
Query: 1627 YYLVFTEWVKLQQRVETDDVVNIVFIRQLFEKGVIDSKEKVIEFIKAALELSVNSFKQSD 1686
+VF WV L + T+D F+ QL ++G++ E I+F + LE + +F ++
Sbjct: 1587 IIIVFVSWVHLLRNSATNDETKAAFVYQLHKQGILSEPELCIQFFRCNLEAVLVAFLEAA 1646
Query: 1687 PTGEV-FTSIDALSRLITSLLVVQELNVE----ERKEYLNLLLSVVTLVFAKDHQTNMTS 1741
+ ++DA + L+ +++ E + E + +++++ VFA+ H +
Sbjct: 1647 SVNAPDYFNVDAYASLLVNVVKYTEGSTEGTVSSKSVLFRKIIALIIGVFAELHNSMAEF 1706
Query: 1742 FNERPYFRLYSSLLSDWDKLRDHHFIRVSDSVVRKSLIEFDQYFFDIFASFLHSY---QP 1798
+++ +FRL+SS+LS+ D +D + F DI++ L + QP
Sbjct: 1707 VHQKTFFRLFSSILSELDDAKD----------------VLESCFVDIYSVILECFLAIQP 1750
Query: 1799 IAFPGFSFAWITLISHRMFLPKVLRSKELYGWDKLVLLLIDLMKFLSQYIKKDNVPDSIS 1858
+FP F+FAW++LISH LPKVL D +L+ +KFL +K D
Sbjct: 1751 RSFPAFTFAWLSLISHSYLLPKVLLVNNDKINDLFSEILMSFLKFLD--LKDDIDKAQFK 1808
Query: 1859 VIYKGALRIFLGISNDVPEFLIQNHYKLVKNVPPTCIQLRNIILSAIPKKMMIPDPFVSE 1918
++Y G LRI L + +D P FL + Y+L+ +P C+QLRN++LSA P + +PDPF
Sbjct: 1809 LLYNGFLRIILVLLHDFPGFLATHCYQLIPYIPLECVQLRNMVLSAFPSDLHLPDPFAQG 1868
Query: 1919 ITEDNCKDI---PQVFYDPSQDLKSLKKPIINYLRIPSSSLLRTICGGMFRTELEYENGI 1975
+ ++ P + S L+ + SS E+
Sbjct: 1869 LKVGRLPEVTRAPLISNSVSASLEKFASALDLEACFSSSKPAEV---AKLLLEVYSSQDT 1925
Query: 1976 GYDENNVDVNLIHAIVTHVAVEVGLEVEKASKNAVFNVKSSYYTLLFGLLSDGNDEVKFH 2035
N + ++ H + A + F KS ++ + + + ++
Sbjct: 1926 PTKLNEWANYFMLCLIRHATRD-----SPAKQAPQFQSKSPECVIISTMNRSCDSKCRYF 1980
Query: 2036 IIQAMVNQLRYPNVHTHWFNFALKLMFQSDQWPDDQLSTXXXXXXXXXXXXXXVNKPHPW 2095
++ A+ NQLRYP+ HT++ + +F+S +L N+PHPW
Sbjct: 1981 LLTAIANQLRYPSSHTYYASCCFLYLFKSSSNNPQEL-LIKEQMTTVLLERIICNRPHPW 2039
Query: 2096 GVVVTFMDLLKLEGTKMIEKPFINDIPEIHAIMKNLQKYALTSSS 2140
G+++TF +LLK E + P+I EI + +L ++ + SS
Sbjct: 2040 GLLITFTELLKNEDYNFWKHPYIKRNDEICRLFDSLHEHVMAPSS 2084
Score = 78.6 bits (192), Expect = 1e-13
Identities = 56/190 (29%), Positives = 100/190 (52%), Gaps = 9/190 (4%)
Query: 1109 PDLKRLFQMAVSKSVREILIPAVEKAANMAVQSTVNIVLKDFATEVDEQKLKTAAINMVQ 1168
P +K + Q+ + +SV EI+ V ++ +A +T +++ KDFA E + +L AA M +
Sbjct: 1129 PAIKNITQLIIQQSVLEIISAVVRRSVGIAAITTKSLLQKDFAAESNPSRLLLAARQMAK 1188
Query: 1169 YLAQNVAHSISVPLLKDTIRNTTQSLTPNLINMTNSPIAE-LNTAIDDNIAIAVSPIEKA 1227
LA N+A L+ + N +++ + ++ +A+ ++ + N+ +A S IE
Sbjct: 1189 TLAGNLAMVTCREPLQMLMINNFRTIALQDVENVHAAVAQAIDELVSQNLFVASSVIESV 1248
Query: 1228 AVERAIQEVNEKLVQAVAVRRYHLERRSDQPFV----AQNINRFSLNLPDPLGLKPTGVT 1283
A E AI E++ ++ + R H + + PFV A N++ LNLP L L + +T
Sbjct: 1249 ASETAIAEIDAEIEHMIVERVRHRKTTPNLPFVDPAGAANLH---LNLPSVLKLS-SELT 1304
Query: 1284 REQFSLYEQF 1293
+QF LYE F
Sbjct: 1305 PQQFQLYENF 1314
>Hs22067248 [K] KOG1831 Negative regulator of transcription
Length = 1805
Score = 254 bits (649), Expect = 1e-66
Identities = 196/759 (25%), Positives = 347/759 (44%), Gaps = 101/759 (13%)
Query: 621 QDVEKKMQTYLQKMYNKE----MAIKDIVDILRKLRDSDDSNDQDIFCCIIHAVIAETTF 676
++++ + +Y Q++YN M++ +++++L++ +DS ++++F C++ + E F
Sbjct: 271 KEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQRFKDSTIKREREVFNCMLRNLFEEYRF 330
Query: 677 FKEYPLEALATTSVLFGSMILFDLLRGFVLDVAFQIIYTFASESPDSKMFKF-------- 728
F +YP + L T+ LFG +I L+ L +A + + + SKM+ F
Sbjct: 331 FPQYPDKELHITACLFGGIIEKGLVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRF 390
Query: 729 ---------------AVQALYAFRMRLNEYSPFCKRLLDEIXXXXXXXXXXXXXXESAAN 773
++ F L EY + ++ D + A
Sbjct: 391 KNRLKDYPQYCQHLASISHFMQFPHHLQEYIEYGQQSRDPPVKMQGSITTPGSIALAQAQ 450
Query: 774 PNVSIPEQKAPALVE----------------------------------LNYFNINEVIS 799
+P KAP + +N NI+ ++
Sbjct: 451 AQAQVPA-KAPLAGQVSTMVTTSTTTTVAKTVTVTRPTGVSFKKDVPPSINTTNIDTLLV 509
Query: 800 PVTQEV----PPREVTEAILFNVNNITMSNFDTKIVELKALLEEKYYQWFSNYLVNQRSK 855
Q PP + E I F NN++ SN K+ ELK ++E++ W S YLV +R
Sbjct: 510 ATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVS 569
Query: 856 TEPNYHPLYAKMLKIIDSKTLHAYMLNFTYKQLFIMLSTKELGQ--TEKTHMKNLSSWLG 913
EPN+H LY+ L + + + +LN TY+ + ++L++ + ++++ +KNL WLG
Sbjct: 570 IEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLG 629
Query: 914 SITLSLDIPIKHKHIAFRELLLDAHKNDR--LTVVIPFVARIIMQSKDSKVFCPPNPWTM 971
ITL+ + PI H + + LLL+A+ + L V+PFVA+++ S S VF PPNPWTM
Sbjct: 630 MITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSVVFRPPNPWTM 689
Query: 972 GILKLLLELNQKTDWPLSLSFEVEVLFKHLNLQFDDISPSNYLDIPDAAEYLSGNLRALS 1031
I+ +L EL+Q+ D L+L FE+EVL K+L L +++ P N L D + L LS
Sbjct: 690 AIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLD---EQLS 746
Query: 1032 VEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIISNGYGNAMNDQASLET 1091
K N Y A
Sbjct: 747 APKKDVKQPEELPPITTTTTSTTPATNTTCTATVPPQPQYSYHDINVYSLA--------- 797
Query: 1092 SDAPHSSLVGN-SVFVTHPDLKRLFQMAVSKSVREILIPAVEKAANMAVQSTVNIVLKDF 1150
APH +L +F HP LK+ + A+ ++V+E++ P V+++ +A+ + IV KDF
Sbjct: 798 GLAPHITLNPTIPLFQAHPQLKQCVRQAIERAVQELVHPVVDRSIKIAMTTCEQIVRKDF 857
Query: 1151 ATEVDEQKLKTAAINMVQYLAQNVA---------HSISVPLLKDTIRNTTQSLTPNLINM 1201
A + +E +++ AA +M++ L +A SIS LK++ + ++ +P M
Sbjct: 858 ALDSEESRMRIAAHHMMRNLTAGMAMITCREPLLMSISTN-LKNSFASALRTASPQQREM 916
Query: 1202 TNSPIAELNTAIDDNIAIAVSPIEKAAVERAIQEVNEKLVQAVAVRRYHLE--RRSDQPF 1259
+ A+L DN +A I+K AVE+A E++++L +R++ + RR P
Sbjct: 917 MDQAAAQL---AQDNCELACCFIQKTAVEKAGPEMDKRLATEFELRKHARQEGRRYCDPV 973
Query: 1260 VAQNINRFSLNLPDPLGLKPTGVTREQFSLYEQFPASMP 1298
V + + +P+ + LK GV +Q ++YE+F ++P
Sbjct: 974 V---LTYQAERMPEQIRLKVGGVDPKQLAVYEEFARNVP 1009
Score = 225 bits (574), Expect = 5e-58
Identities = 174/675 (25%), Positives = 311/675 (45%), Gaps = 81/675 (12%)
Query: 1512 KDVVWWLVYALDPRKFNVPVVRSLLEVNLINIAEFDAVLVTAMKNGMAG-ATEFSMNLIR 1570
K + L+ D K+NV V L+ +L+N+ ++D L +M+NG+ A F+M L++
Sbjct: 1137 KQITRCLIECRDEYKYNVEAVELLIRNHLVNMQQYDLHLAQSMENGLNYMAVAFAMQLVK 1196
Query: 1571 DTVMADSPI--LMRLDFIRILGYLRTINT------PE-IKAFLEEYEQCRAVPVSKT--- 1618
++ + + + D + L IN PE + +E + +
Sbjct: 1197 ILLVDERSVAHVTEADLFHTIETLMRINAHSRGNAPEGLPQLMEVVRSNYEAMIDRAHGG 1256
Query: 1619 ------TSITKVERY-----------YLVFTEWVKLQQRVET---DDVVNIVFIRQLFEK 1658
+ I++ Y YL+ EWV L F+ Q+ ++
Sbjct: 1257 PNFMMHSGISQASEYDDPPGLREKAEYLL-REWVNLYHSAAAGRDSTKAFSAFVGQMHQQ 1315
Query: 1659 GVIDSKEKVIEFIKAALELSVN------SFKQSDPTG-------EVFTSIDALSRLITSL 1705
G++ + + + F + E+ V + +Q +P + + ++DA RLI L
Sbjct: 1316 GILKTDDLITRFFRLCTEMCVEISYRAQAEQQHNPAANPTMIRAKCYHNLDAFVRLIALL 1375
Query: 1706 LVV--QELNVEERKEYLNLLLSVVTLVFAKDHQTNMTSFNERPYFRLYSSLLSDWDKLRD 1763
+ + N + LN +L +V V +DH + F + PY R++ LL + +
Sbjct: 1376 VKHSGEATNTVTKINLLNKVLGIVVGVLLQDHDVRQSEFQQLPYHRIFIMLLLELNAPE- 1434
Query: 1764 HHFIRVSDSVVRKSLIEFDQYFFDIFASFLHSYQPIAFPGFSFAWITLISHRMFLPKVL- 1822
V +++ ++L F F H +P PGF +AW+ LISHR+F+ ++L
Sbjct: 1435 ----HVLETINFQTLTAFCNTF--------HILRPTKAPGFVYAWLELISHRIFIARMLA 1482
Query: 1823 RSKELYGWDKLVLLLIDLMKFLSQYIKKDNVPDSISVIYKGALRIFLGISNDVPEFLIQN 1882
+ + GW LLIDL K+L+ +++ + + ++YKG LR+ L + +D PEFL
Sbjct: 1483 HTPQQKGWPMYAQLLIDLFKYLAPFLRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDY 1542
Query: 1883 HYKLVKNVPPTCIQLRNIILSAIPKKMMIPDPFVSEITEDNCKDI---PQVFYDPSQDL- 1938
HY +PP CIQLRN+ILSA P+ M +PDPF + D +I P++ + + +
Sbjct: 1543 HYGFCDVIPPNCIQLRNLILSAFPRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMP 1602
Query: 1939 KSLKKPIINYLRIPSSSLLRTICGGMFRTELEYENGIGYDENNVDVNLIHAIVTHVAVEV 1998
KK + +YL+ S + R+ L+ N G N ++ LI+A+V +V +
Sbjct: 1603 PQFKKDLDSYLKTRSPVTFLS----DLRSNLQVSNEPG---NRYNLQLINALVLYVGTQA 1655
Query: 1999 GLEV-EKASKNAVFNVKSSYYTLLF-GLLSDGNDEVKFHIIQAMVNQLRYPNVHTHWFNF 2056
+ K S ++ + S + +F L D + E ++ + A+ NQLRYPN HTH+F+
Sbjct: 1656 IAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSC 1715
Query: 2057 ALKLMFQSDQWPDDQLSTXXXXXXXXXXXXXXVNKPHPWGVVVTFMDLLKLEGTKMIEKP 2116
+ +F + VN+PHPWG+++TF++L+K K
Sbjct: 1716 TMLYLF-----AEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHE 1770
Query: 2117 FINDIPEIHAIMKNL 2131
F++ PEI + +++
Sbjct: 1771 FVHCAPEIEKLFQSV 1785
>At1g02080 [K] KOG1831 Negative regulator of transcription
Length = 2226
Score = 230 bits (586), Expect = 2e-59
Identities = 187/746 (25%), Positives = 330/746 (44%), Gaps = 106/746 (14%)
Query: 1450 TIKNTIVEILSFISRSNQKDQLSLKVSQAVVNSLFGSNESKLCRDVXXXXXXXXXXXXIV 1509
T K I E+ I R +D+ + V+Q +L+ + S L V +
Sbjct: 1502 TQKAVISEVPEIILRCISRDEAAFAVAQKAFKALYENASSNL--HVSANLAILVAIRDVC 1559
Query: 1510 AR--KDVVWWLVYALDPRKFNVPVVRSLLEVNLINIAEFDAVLVTAMKNGM-AGATEFSM 1566
R K++ W++Y+ + RK N + L++ L+++AE++ + + G AT+F++
Sbjct: 1560 KRVVKELTSWVIYSEEDRKLNKDITIGLIQRELLSLAEYNVHMAKHLDGGRNKTATDFAI 1619
Query: 1567 NLIRDTVMADSPILMRLDFI------------------RILGYLRT--INTPEIKAFL-- 1604
+L++ V +S ++ L + +++ +R NT +
Sbjct: 1620 SLLQSLVTEESSVISELHSLVDALAKLASKSGSSESLQQLIDIIRNPVTNTAGLSDSSTG 1679
Query: 1605 --------EEYEQCRAVPVSKTTSITKVE--------RYYLVFTEWVKLQQRVETDDVVN 1648
+E C ++TS+ VE R +F W ++ + ++
Sbjct: 1680 NDNNDRQKDEKVACNTTNTEESTSLDYVESDPAGFQNRVSTLFKNWYQICELPGANETAC 1739
Query: 1649 IVFIRQLFEKGVIDSKEKVIEFIKAALELSVNSFKQSD------------PTGEVFTSID 1696
++ L + G++ + F + LELSV S+ P F ID
Sbjct: 1740 SQYVLHLHQTGLLKGDDTTESFFRILLELSVAHCISSEDINSGAVQSPQQPQSPSFLIID 1799
Query: 1697 ALSRLITSLLVVQELNVEERKEYLNLLLSVVTLVFAKDHQTNMTSFNERPYFRLYSSLLS 1756
++L+ S+L + V KD + TS N +PYFRL+ + L
Sbjct: 1800 MYAKLVFSILKIMADTVR---------------FIQKDAEDKKTSLNSKPYFRLFINWLL 1844
Query: 1757 DWDKLRDHHFIRVSDSVVRKSLIEFDQYFFDIFASFLHSYQPIAFPGFSFAWITLISHRM 1816
D L +D + L FA+ H+ QP+ P FSFAW+ L+SHR
Sbjct: 1845 DLCSLDPG-----TDGANFQVL--------TAFANAFHALQPLKIPAFSFAWLELVSHRS 1891
Query: 1817 FLPKVLRSKELYGWDKLVLLLIDLMKFLSQYIKKDNVPDSISVIYKGALRIFLGISNDVP 1876
F+PK+L GW + LL+DL++FL +++ + + +YKG LR+ L + +D P
Sbjct: 1892 FMPKLLTVNGQKGWPYVQRLLVDLLQFLEPFLRNAELGGPVHFLYKGTLRVLLVLLHDFP 1951
Query: 1877 EFLIQNHYKLVKNVPPTCIQLRNIILSAIPKKMMIPDPFVSEITEDNCKDIPQV-----F 1931
EFL H+ +P +CIQ+RNIILS+ P+ M +PDP + D +I +
Sbjct: 1952 EFLCDYHFTFCDVIPSSCIQMRNIILSSFPRNMRLPDPSTPNLKIDLLPEIVEAPCILSE 2011
Query: 1932 YDPSQDLKSLKKPIINYL--RIPSSSLLRTICGGMFRTELEYENGIGYDENNVDVNLIHA 1989
D + K +K + YL R +S+ L + + + E + V LI++
Sbjct: 2012 VDAALKAKQMKNDVDEYLTSRQQNSTFLSELKTKLLLSSSEASSA----GTRYSVPLINS 2067
Query: 1990 IVTHVAVEVGLEVEKASKNAVFNVKSSYYTLLFGLLS-DGNDEVKFHIIQAMVNQLRYPN 2048
+V + ++ ++ +A + NV + +F LS + + E ++ + A+ NQLRYPN
Sbjct: 2068 LVLYTGMQ-AIQQLQAGETQAQNVVA---LQMFKYLSMELDTEGRYLFLNAIANQLRYPN 2123
Query: 2049 VHTHWFNF-ALKLMFQSDQWPDDQLSTXXXXXXXXXXXXXXVNKPHPWGVVVTFMDLLKL 2107
HTH+F+F L L F+SDQ VN+PHPWG+++TF++L+K
Sbjct: 2124 NHTHYFSFIMLYLFFESDQ------EIIQEQITRVLLERLIVNRPHPWGLLITFIELIKN 2177
Query: 2108 EGTKMIEKPFINDIPEIHAIMKNLQK 2133
++ FI PEI + +++ +
Sbjct: 2178 PRYSFWKQAFIRCAPEIEKLFESVAR 2203
Score = 154 bits (388), Expect = 2e-36
Identities = 77/233 (33%), Positives = 139/233 (59%), Gaps = 12/233 (5%)
Query: 804 EVPPREVTEAILFNVNNITMSNFDTKIVELKALLEEKYYQWFSNYLVNQRS--------K 855
E PP +V + + F +NNI+ +N ++K E +L ++YY WF+ Y+V +R+
Sbjct: 813 EAPPSDVQDKVSFIINNISTTNIESKGKEFAEILPQQYYPWFAQYMVMKRAMCLIPDRAS 872
Query: 856 TEPNYHPLYAKMLKIIDSKTLHAYMLNFTYKQLFIMLSTKELGQT--EKTHMKNLSSWLG 913
EPN+H LY K L +DSK L +L TY+ ++L ++ + + E++ +KNL SWLG
Sbjct: 873 IEPNFHDLYLKFLDKVDSKLLFKEILQNTYENCKVLLGSELIKSSSEERSLLKNLGSWLG 932
Query: 914 SITLSLDIPIKHKHIAFRELLLDAHKNDRLTVVIPFVARIIMQSKDSKVFCPPNPWTMGI 973
+T+ + ++ + I + L+++A++ + VIPF ++++ ++S + PPNPWTM I
Sbjct: 933 RLTIGRNYVLRAREIDPKSLIVEAYEKGLMIAVIPFTSKVLEPCQNSIAYQPPNPWTMAI 992
Query: 974 LKLLLELNQKTDWPLSLSFEVEVLFKHLNLQFDDISPSNYLDIPDAAEYLSGN 1026
L LL E+ + ++L F++EVLFK+L ++ ++ P++ L D + GN
Sbjct: 993 LGLLAEIYSMPNLKMNLKFDIEVLFKNLGVEMKEVVPTSLL--KDRKREIDGN 1043
Score = 89.4 bits (220), Expect = 6e-17
Identities = 62/196 (31%), Positives = 109/196 (54%), Gaps = 9/196 (4%)
Query: 1103 SVFVTHPDLKRLFQMAVSKSVREILIPAVEKAANMAVQSTVNIVLKDFATEVDEQKLKTA 1162
S F H +R+ +A+ ++++EI+ V+++ +A Q+T +VLKD+A E DE ++ A
Sbjct: 1161 SAFGMHFPFQRVVPLAMDRAIKEIVSGIVQRSVCIACQTTKELVLKDYALEPDESRIYNA 1220
Query: 1163 AINMVQYLAQNVAHSISVPLLKDTI----RNTTQSLTPNLINMTNSPIAELNTAIDDNIA 1218
A MV LA ++AH L+ +I RN+ Q L N+ N I +L T +DN+
Sbjct: 1221 AHLMVASLAGSLAHVTCKEPLRTSISGHLRNSLQGL--NISNDALEQIVQLVT--NDNLD 1276
Query: 1219 IAVSPIEKAAVERAIQEVNEKLVQAVAVRRYHLERRSDQPFVAQNINRFSLN-LPDPLGL 1277
+ + IE+AA E+AIQ ++ + Q + +RR H + F +++ S++ +P+ L
Sbjct: 1277 LGCAAIEQAATEKAIQTIDADIAQQLLLRRKHRDGAGSSFFDPNILSQNSVSFIPESLRP 1336
Query: 1278 KPTGVTREQFSLYEQF 1293
KP ++ Q +YE F
Sbjct: 1337 KPGHLSLSQQRVYEDF 1352
Score = 83.2 bits (204), Expect = 4e-15
Identities = 71/271 (26%), Positives = 117/271 (42%), Gaps = 18/271 (6%)
Query: 493 ILDEVFEKLPIRDSLKLSPTAMHLGYLKFSEYIERNITLKT---------FVPTLDFIEA 543
IL V E +P+ S++L+ A G L ++ + + FV + F E+
Sbjct: 402 ILSVVLESVPVSSSIRLAVLASLRGLLDIENWLPNCLYMYKDLFAEECLKFVKNVHFSES 461
Query: 544 ---QTNIDELDPALKSVKLLNLHSLHSLIYRTANLKLSADERVALNNVIFKALISFPRLI 600
+ I L + L SL ++ N S+ + V L P+L
Sbjct: 462 DDFRAKIFHPSDPLSDLHLEATTSLLKVLKAHDNAITSSQLVEEIEKVNAAILDCNPKLQ 521
Query: 601 NYGYGHDDAIVANGDHAPIPQDVEKKMQTYLQKMYNKEMAIKDIVDILRKLRDSDDSNDQ 660
N A A GD DVE + Y +M++ +++ +V +L + ++S ++
Sbjct: 522 NGEAKDSSAPNAYGD------DVEAEANAYFHQMFSSHLSVDAMVQMLSRYKESLVPREK 575
Query: 661 DIFCCIIHAVIAETTFFKEYPLEALATTSVLFGSMILFDLLRGFVLDVAFQIIYTFASES 720
IF C+I + E FF +YP L S+LFGS+I L+ L +A +++ +
Sbjct: 576 LIFECMIANLFEEYRFFPKYPERQLKIASILFGSVIKHQLISSLTLGMALRLVLDSLRKP 635
Query: 721 PDSKMFKFAVQALYAFRMRLNEYSPFCKRLL 751
DSKMF F +AL F RL E +C +L
Sbjct: 636 ADSKMFLFGSKALEQFVNRLVELPQYCNHIL 666
>7303881 [K] KOG1831 Negative regulator of transcription
Length = 1766
Score = 201 bits (511), Expect = 1e-50
Identities = 147/541 (27%), Positives = 253/541 (46%), Gaps = 52/541 (9%)
Query: 1625 ERYYLVFTEWVKL---QQRVETDDVVNI-VFIRQLFEKGVIDSKEKVIEFIKAALELSVN 1680
E+ + +WV L Q + T D N F++++ G++ + + + F + A + +
Sbjct: 1232 EKTEFLLKDWVALYTQQNQQSTRDARNFGAFVQKMNTYGILKTDDLITRFFRQATHICTD 1291
Query: 1681 ---------SFKQSDPTGEVFTSIDALSRLITSLL--VVQELNVEERKEYLNLLLSVVTL 1729
S + ++F IDA LI L+ + N + LN +L +V
Sbjct: 1292 VVYRMFAEPSLPINQAKNKIFQWIDAFVHLIAMLVRHSGEAGNPTTKINLLNKVLGIVLG 1351
Query: 1730 VFAKDHQTNMTSFNERPYFRLYSSLLSDWDKLRDHHFIRVSDSVVRKSLIEFDQYFFDIF 1789
KDH+ SF + Y R + L + + V+ +SL+ F
Sbjct: 1352 TLIKDHEMRGVSFQQVGYHRFFMMLFMEL----------CTADVILESLMHS---IVSAF 1398
Query: 1790 ASFLHSYQPIAFPGFSFAWITLISHRMFLPKVL-RSKELYGWDKLVLLLIDLMKFLSQYI 1848
A H P PGF FAW+ LISHR+FL ++L + GW LL DL K+L+ ++
Sbjct: 1399 AYTYHLLNPSVAPGFCFAWLELISHRVFLGRILVQIPGQKGWPLYAQLLQDLFKYLAPFL 1458
Query: 1849 KKDNVPDSISVIYKGALRIFLGISNDVPEFLIQNHYKLVKNVPPTCIQLRNIILSAIPKK 1908
+ + + ++YKG LR+ L + +D PEFL H+ +PP C+Q+RNIILSA P+
Sbjct: 1459 RNTELGKPVQLLYKGTLRVLLVLLHDFPEFLCDYHFGFCDTIPPNCVQMRNIILSAFPRN 1518
Query: 1909 MMIPDPFVSEITEDNCKD---IPQVFYDPSQDLK--SLKKPIINYLRIPSSSLLRTICGG 1963
M +PDPF + D D P+V +++ + KK + +YL+ + + G
Sbjct: 1519 MRLPDPFTPNLKVDMLSDSSNAPKVLSSYIMNIQPANFKKDLDSYLKARAPVTFLSELRG 1578
Query: 1964 MFRTELEYENGIGYDENNVDVNLIHAIVTHVAVEVGLEVEKASKNAVFNVK----SSYYT 2019
++ E G Y ++ L++A+V +V + + +KN V N S++
Sbjct: 1579 --HLQVTSEPGTRY-----NMALMNALVMYVGTQAIALIR--NKNFVPNTSNIAHSAHMD 1629
Query: 2020 LLFGLLSDGNDEVKFHIIQAMVNQLRYPNVHTHWFNFALKLMFQSDQWPDDQLSTXXXXX 2079
+ L D + E ++ + A+ NQLRYPN HTH+F+ A+ +F +
Sbjct: 1630 IFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCAVLHLF-----AEANSEAIQEQI 1684
Query: 2080 XXXXXXXXXVNKPHPWGVVVTFMDLLKLEGTKMIEKPFINDIPEIHAIMKNLQKYALTSS 2139
VN+PHPWG+++TF++L+K K + F++ PEI + +++ + L S
Sbjct: 1685 TRVLLERLIVNRPHPWGLLITFIELIKNPIYKFWDHDFVHCAPEITKLFESVARSCLAKS 1744
Query: 2140 S 2140
+
Sbjct: 1745 N 1745
Score = 143 bits (361), Expect = 3e-33
Identities = 81/236 (34%), Positives = 136/236 (57%), Gaps = 7/236 (2%)
Query: 790 NYFNINEVISPVTQE---VPPREVTEAILFNVNNITMSNFDTKIVELKALLEEKYYQWFS 846
N NI+ ++ +E VPP V + F NN++ N K E+K ++ ++Y+ W +
Sbjct: 394 NATNIDTLLVANQEEKVTVPPEPVQDKTAFIFNNLSQLNIPQKCDEIKEIMTKEYWPWLA 453
Query: 847 NYLVNQRSKTEPNYHPLYAKMLKIIDSKTLHAYMLNFTYKQLFIMLSTKE--LGQTEKTH 904
YLV +R+ E N+H LY L + + ++ ++ T + + ++L + + + ++++
Sbjct: 454 QYLVLKRASMEFNFHTLYYNFLDALKNGEINRFVTKETLRNIKVLLRSDKGVINFSDRSL 513
Query: 905 MKNLSSWLGSITLSLDIPIKHKHIAFRELLLDA-HKNDR-LTVVIPFVARIIMQSKDSKV 962
+KNL WLG +TL + PI + + LL +A HK + L V+PFVA+I+ S S++
Sbjct: 514 LKNLGHWLGMMTLGRNRPILQLDLDLKSLLAEAYHKGQQELLFVVPFVAKILESSAKSRI 573
Query: 963 FCPPNPWTMGILKLLLELNQKTDWPLSLSFEVEVLFKHLNLQFDDISPSNYLDIPD 1018
F PNPWTMGI+ +L EL+Q+ D L+L FE+EVL K LNL+ + YL P+
Sbjct: 574 FRSPNPWTMGIMYVLAELHQEPDLKLNLKFEIEVLCKTLNLELAKLRQVIYLKDPN 629
Score = 85.9 bits (211), Expect = 6e-16
Identities = 42/138 (30%), Positives = 85/138 (61%), Gaps = 5/138 (3%)
Query: 618 PIPQDVEKKMQTYLQKMYNKE----MAIKDIVDILRKLRDSDDSNDQDIFCCIIHAVIAE 673
P+ ++VE ++ +Y Q++YN + ++I +++DIL++ ++S + +Q++F C++ + E
Sbjct: 170 PVSKEVEDEVNSYFQRIYNHQPNPTLSIDEVLDILQRFKESSNRREQEVFLCMLRNLFEE 229
Query: 674 TTFFKEYPLEALATTSVLFGSMILFDLLRGFV-LDVAFQIIYTFASESPDSKMFKFAVQA 732
FF +YP + L T+ LFG +I +L+ FV L ++ + + + SK++ F V A
Sbjct: 230 YRFFCQYPEKELQITAQLFGGIIDRNLVPTFVALGLSLRCVLDALRKPDGSKLYYFGVTA 289
Query: 733 LYAFRMRLNEYSPFCKRL 750
L FR RL+ Y+ +C+ +
Sbjct: 290 LDRFRTRLHTYNKYCEHI 307
Score = 72.4 bits (176), Expect = 7e-12
Identities = 57/211 (27%), Positives = 104/211 (49%), Gaps = 14/211 (6%)
Query: 1108 HPDLKRLFQMAVSKSVREILIPAVEKAANMAVQSTVNIVLKDFATEVDEQKLKTAAINMV 1167
+P +K + AV +++ + L P V+++ +A +T I+ KDFA + DE +++TAA MV
Sbjct: 760 NPGIKHMVVNAVERTITDWLQPIVDRSIRIACATTEQIIRKDFALDADENRMRTAAHQMV 819
Query: 1168 QYLAQNVAHSISVPLLKDTI-RNTTQSLTPNLINMTNS--PIAELNTA----IDDNIAIA 1220
+ LA +A KD I R +Q+L L++ N +AE+ A +N+ +
Sbjct: 820 RNLAAGMAMITG----KDEIARAISQNLHKALLSGLNGMPSMAEIQAAAMQLASENVELV 875
Query: 1221 VSPIEKAAVERAIQEVNEKLVQAVAVRRYHLERRSDQPFV-AQNINRFSLNLPDPLGLKP 1279
+ I+K + E+A E++ +L R+ + R FV AQ + LP+ + +K
Sbjct: 876 CAFIQKTSAEKAAAEIDRRLSTDFETRK--IAREEGNRFVDAQILTYQQERLPEAVRIKV 933
Query: 1280 TGVTREQFSLYEQFPASMPSDSSRSPLETIL 1310
+++Y +F S+P S + L
Sbjct: 934 GAAPATLYAVYSEFARSIPGFQQMSDRDIAL 964
>CE01337 [K] KOG1831 Negative regulator of transcription
Length = 2500
Score = 193 bits (490), Expect = 3e-48
Identities = 171/764 (22%), Positives = 326/764 (42%), Gaps = 124/764 (16%)
Query: 621 QDVEKKMQTYLQKMY--NKEMAIKDIVDILRKLRDSDDSNDQDIFCCIIHAVIAETTFFK 678
+D++++ +Y +K+Y N M++++++D+L++ R S+D ++ + C++ + E FF
Sbjct: 924 EDIQEEANSYFEKIYSVNNAMSVENLIDLLKRFRVSNDRRERLVLACVVKNLFEEYRFFH 983
Query: 679 EYPLEALATTSVLFGSMILFDLLRGFVLDVAFQIIYTFASESPDSKMFKFAVQALYAFRM 738
EYP L TT+ ++G +I D++ A + + S P++ ++ F + AL R
Sbjct: 984 EYPERELRTTAAVYGGIIREDIISNVQFATAVRKVIESLSADPNTMLWTFGIVALQHCRS 1043
Query: 739 RL-------------NEYSPFCKRLLDEIXX----------------------------- 756
+L ++ F + L D +
Sbjct: 1044 KLCAYPKVCQMIVSSENFARFPQLLKDYVIAGVKGELPPEGGRHTPVGSAQAGSASSTPT 1103
Query: 757 -XXXXXXXXXXXXESAANPNVSIPEQKAPALVELNYFNINEVISPVTQE-----VPPREV 810
++ +P S+P + + L+Y N++ ++ ++ P +
Sbjct: 1104 PAAAPTNWGAVARAASVDPKNSLPANRTGNV--LSYTNVDTLVMATNKDGAEIAQPAEAI 1161
Query: 811 TEAILFNVNNITMSNFDTK---IVELKALLEEKYYQWFSNYLVNQRSKTEPNYHPLYAKM 867
+ I F NN++ SN K +VE+ + + + W + Y+V +R E N+ PLY +
Sbjct: 1162 VDKISFLFNNLSQSNLIQKKDEVVEMISDHGDAFTLWLAQYIVMKRVSIEQNFQPLYNQF 1221
Query: 868 LKIIDSKTLHAYMLNFTYKQLFIMLSTKELGQTEKTHMKNLSSWLGSITLSLDIPIKHKH 927
+ I++ L ++ +KNL SWLG+IT++ + PI
Sbjct: 1222 VNAIENPYL----------------------DHDRQLLKNLGSWLGAITIARNKPILLND 1259
Query: 928 IAFRELLLDAHKNDR--LTVVIPFVARIIMQSKDSKVFCPPNPWTMGILKLLLELNQKTD 985
+ + LLL+A+ + L V+PF+++I+ + +F P W ILK+L EL+ + D
Sbjct: 1260 LDLKSLLLEAYYKGQAELLYVVPFISKILTACSKTSLFTPTCAWIRSILKVLAELHNEPD 1319
Query: 986 WPLSLSFEVEVLFKHLN-----LQFDDI---------SPSNYLDI-----PDAAEYLSGN 1026
++L FE+EVL K LN LQ D I P D+ P+AA +
Sbjct: 1320 LKINLKFEIEVLCKELNVDLNQLQMDGILKDTEKLVRVPQQLCDVKLLTRPEAASPVQSK 1379
Query: 1027 LR-ALSVEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIISNGYGNAMND 1085
+ + S E+ ++ N A +D
Sbjct: 1380 IHMSGSAEQLSGMSPAIPDQVKPATPQPTEAELQSGTGGGGSQGAEAQVVPNVTHFAYHD 1439
Query: 1086 QASLETSDA--PHSSLVGN-SVFVTHPDLKRLFQMAVSKSVREILIPAVEKAANMAVQST 1142
++ T D PH +V + +F HP K L + A+ +++E++ P E+A +A+ T
Sbjct: 1440 -INVLTYDGLIPHVKIVSHLPLFQLHPHAKHLVRPAMIHAIKELIGPVTERALKIAMTVT 1498
Query: 1143 VNIVLKDFATEVDEQKLKTAAINMVQYLAQNVA------------HSISVPLLKDTIRNT 1190
++V KDFA + +EQ L+ A+ +M++ + +A HS ++R+T
Sbjct: 1499 ESLVRKDFALDPEEQNLRAASFHMMRAMTAGMAMITCRDPLASSMHSNLANAFSSSLRST 1558
Query: 1191 TQSLTPNLINMTNSPIAELNTAIDDNIAIAVSPIEKAAVERAIQEVNEKLVQAVAVRRYH 1250
+ P + M A T DN+ ++ + I K A E+A Q++ EK ++A +R
Sbjct: 1559 --AANPEMKQMIEDAAA---TITQDNVELSTNFIVKTACEKATQDI-EKRLEADYQKR-- 1610
Query: 1251 LERRSDQPFVAQNI-NRFSLNLPDPLGLKPTGVTREQFSLYEQF 1293
+ +++ F I LP + P + +Y+QF
Sbjct: 1611 IAAKAEMSFYRDEIAAAIHAQLPKAIATVPGPTDKALMGIYDQF 1654
Score = 191 bits (486), Expect = 8e-48
Identities = 140/533 (26%), Positives = 252/533 (47%), Gaps = 52/533 (9%)
Query: 1629 LVFTEWVKL-----QQRVETDDVVNIVFIRQLFEKGVIDSKEKVIEFIKAALE----LSV 1679
++ EW+ L QR + + + I+ + E GV+ + +K+ +F + +E +SV
Sbjct: 1951 IIMREWIGLCYSPTGQRSPQESLAQM--IQLMHEHGVLATDDKITQFFRLCVENCVDISV 2008
Query: 1680 NSFKQSD-----PTGEV----FTSIDALSRLITSLLVVQELNVEERK-EYLNLLLSVVTL 1729
K PT + + ++DA +L+ ++ + + K L LL+++
Sbjct: 2009 RVMKSEQLANGLPTTLIRHRCYYTLDAFVKLMALMIRHSDNGQSQNKINLLKKLLNIIVG 2068
Query: 1730 VFAKDHQTNMTSFNERPYFRLYSSLLSDWDKLRDHHFIRVSDSVVRKSLIEFDQYFFDIF 1789
V DH+ FN PY R+ L+S ++++ +++ + + L F Q FF +
Sbjct: 2069 VLHMDHEVRKQDFNAMPYHRI---LISLFNEITGPDPLKLLEPIAWSILEAFGQTFFAL- 2124
Query: 1790 ASFLHSYQPIAFPGFSFAWITLISHRMFLPKVLRSKELYGWDKLVL-------LLIDLMK 1842
QP PGF+FAW+ ++ HR + ++L + + V L+I +K
Sbjct: 2125 -------QPRRMPGFAFAWLDIVGHRNVIGRLLANTGIAETVDAVKTAATYTQLIISHLK 2177
Query: 1843 FLSQYIKKDNVPDSISVIYKGALRIFLGISNDVPEFLIQNHYKLVKNVPPTCIQLRNIIL 1902
FL+ +++ +P SI+++YKG LR+ L I +D PE L + HY + +PP C+QLRN+IL
Sbjct: 2178 FLAPFLRNIQLPKSIAILYKGTLRVLLVILHDFPELLCEFHYVICDTIPPNCVQLRNLIL 2237
Query: 1903 SAIPKKMMIPDPFVSEITEDNCKDIPQVFYDPSQDLKSLKKPIINYLRIPSSSLLRTICG 1962
SA P++M +PDPF + IP++ +P +L ++ I + +RIP L
Sbjct: 2238 SAYPRQMRLPDPFALNFKQ--VDTIPEMAVEPKSNL-NMATIIPDNIRIPLDEYLANRIS 2294
Query: 1963 GMF----RTELEYENGIGYDENNVDVNLIHAIVTHVAVEVGLEVEKASKNAVFNVKSSYY 2018
F T L+ +N G N +N + V A+E L + + + + +SY
Sbjct: 2295 VDFLPNLPTLLQTQNQAGTKYNTTVMNALVLYVGIRAIE-HLHLRRQRISTLNIAHTSYM 2353
Query: 2019 TLLFGLLSDGNDEVKFHIIQAMVNQLRYPNVHTHWFNFALKLMFQSDQWPDDQLSTXXXX 2078
+ L + E ++ + + NQLRYPN HTH+F+ +F+ + T
Sbjct: 2354 DIFQNLAIQLDTEGRYLLFNGIANQLRYPNAHTHYFSCVFLYLFK-----NSTNDTIQEQ 2408
Query: 2079 XXXXXXXXXXVNKPHPWGVVVTFMDLLKLEGTKMIEKPFINDIPEIHAIMKNL 2131
+PHPWG+++TF++L+K F + PEI + +N+
Sbjct: 2409 ITRILFERLVALRPHPWGLLITFIELIKNPTYNFWRYEFTSCAPEIQRLFQNV 2461
>Hs7706214 [K] KOG1831 Negative regulator of transcription
Length = 316
Score = 131 bits (330), Expect = 1e-29
Identities = 84/266 (31%), Positives = 140/266 (52%), Gaps = 24/266 (9%)
Query: 1789 FASFLHSYQPIAFPGFSFAWITLISHRMFLPKVL-RSKELYGWDKLVLLLIDLMKFLSQY 1847
F + H +P PGF +AW+ LISHR+F+ ++L + + GW LLIDL K+L+ +
Sbjct: 24 FCNTFHILRPTKAPGFVYAWLELISHRIFIARMLAHTPQQKGWPMYAQLLIDLFKYLAPF 83
Query: 1848 IKKDNVPDSISVIYKGALRIFLGISNDVPEFLIQNHYKLVKNVPPTCIQLRNIILSAIPK 1907
++ + + ++YKG LR+ L + +D PEFL HY +PP CIQLRN+ILSA P+
Sbjct: 84 LRNVELTKPMQILYKGTLRVLLVLLHDFPEFLCDYHYGFCDVIPPNCIQLRNLILSAFPR 143
Query: 1908 KMMIPDPFVSEITEDNCKDI---PQVFYDPSQDL-KSLKKPIINYLRIPS-----SSLLR 1958
M +PDPF + D +I P++ + + + KK + +YL+ S S L R
Sbjct: 144 NMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRR 203
Query: 1959 TICGGMFRTELEYENGIGYDENNVDVNLIHAIVTHVAVEVGLEV-EKASKNAVFNVKSSY 2017
T+ ++ E G N ++ LI+A+V +V + + K S ++ + S
Sbjct: 204 TV-------QVSNEPG-----NRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSA 251
Query: 2018 YTLLF-GLLSDGNDEVKFHIIQAMVN 2042
+ +F L D + E ++ + A+ N
Sbjct: 252 HMDIFQNLAVDLDTEGRYLFLNAIAN 277
>ECU11g1370 [K] KOG1831 Negative regulator of transcription
Length = 1461
Score = 56.2 bits (134), Expect = 6e-07
Identities = 39/136 (28%), Positives = 64/136 (46%), Gaps = 7/136 (5%)
Query: 1458 ILSFISRSNQKDQLSLKVSQAVVNSLFGSNESKLCRDVXXXXXXXXXXXXIVARKDVVWW 1517
IL + S KD+ +++ + + L S + D +K+V+ W
Sbjct: 971 ILESVESSEDKDEECIRLCRYITGHLIKSGSKE---DFLFRCMEKIFKISFKTQKEVLGW 1027
Query: 1518 LVYALDPRKFNVPVVRSLLEVNLINIAEFDAVLVTAMKNGMA-GATEFSMNLIRDTVMAD 1576
L+Y+ DPRKF++ +V +E NLIN+ E+D L K +A G +F + L+ + A+
Sbjct: 1028 LIYSNDPRKFSISLVGKFIEHNLINVVEYDQAL---SKIPLADGNLDFVIALLASLITAE 1084
Query: 1577 SPILMRLDFIRILGYL 1592
I DFI L L
Sbjct: 1085 VQICTVYDFICTLEML 1100
Score = 54.7 bits (130), Expect = 2e-06
Identities = 35/127 (27%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Query: 879 YMLNFTYKQL-FIMLSTKELGQTEKTHMKNLSSWLGSITLSLDIPIKHKHIAFRELLLDA 937
+ L F+ K L F+ + ++E K+L LG + L+ + + + F++ ++ +
Sbjct: 616 FYLRFSRKSLEFLKMLLDYRCRSEVKVAKSLGLVLGRVMLAKNRIVTSEQFDFKKFVVKS 675
Query: 938 HKNDRLTVVIPFVARIIMQSKDSKVFCPPNPWTMGILKLLLELNQKTDWPLSLSFEVEVL 997
+ R+ + F++ + Q K VF P NPW M IL LL E++ T P + E++ L
Sbjct: 676 VECRRILFGVSFISSFLRQGKCGIVFIPNNPWVMSILDLLSEIHSCT--PRVVRDEIQGL 733
Query: 998 FKHLNLQ 1004
F+HL+++
Sbjct: 734 FRHLSVE 740
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 110,453,068
Number of Sequences: 60738
Number of extensions: 4540978
Number of successful extensions: 12140
Number of sequences better than 1.0e-05: 8
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 12051
Number of HSP's gapped (non-prelim): 43
length of query: 2140
length of database: 30,389,216
effective HSP length: 122
effective length of query: 2018
effective length of database: 22,979,180
effective search space: 46371985240
effective search space used: 46371985240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)