ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4671 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4671 1657387 1655738 -550
(550 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 526 e-149
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 424 e-118
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 416 e-116
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 194 2e-49
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 162 1e-39
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 160 5e-39
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 159 8e-39
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 149 1e-35
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 116 1e-25
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 91 5e-18
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 89 2e-17
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 87 9e-17
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 83 9e-16
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 77 9e-14
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 69 2e-11
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 63 1e-09
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 54 6e-07
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 526 bits (1355), Expect = e-149
Identities = 268/521 (51%), Positives = 352/521 (67%), Gaps = 14/521 (2%)
Query: 44 DDKTKSKYAVVSSRDADATLGFLEEFDPQVPAITAEQEKRLSRKVTWIIVSLTAFINLIL 103
D + S +V SR AD TL F+EE D VP IT EQEK+L RK+ I + + INL+L
Sbjct: 11 DSISSSDEILVPSRLADVTLAFMEENDAAVPEITPEQEKKLKRKLFLTIFTFVSAINLLL 70
Query: 104 YSDKATASYASILGLWEEVGITQNQYNNSNTLFYVGFIVGQ-ANLYFVQTYPLKYVVSVM 162
Y DKAT SY SILG +E+ G+TQN YN NTLFYVGF +GQ Y Q PL + +
Sbjct: 71 YMDKATLSYDSILGFFEDTGLTQNTYNTVNTLFYVGFAIGQFPGQYLAQKLPLGKFLGGL 130
Query: 163 TALWTIVIFLHCACTNYRSFYVLRFFLGFVESVAIPCLNTTMGQFLTADEKAASAPMFYS 222
A WTI+IFL C N+ LRFFLG ESV IP L TTMG F A E+AA+ P F++
Sbjct: 131 LATWTILIFLSCTAYNFSGVVALRFFLGLTESVVIPILITTMGMFFDASERAAAQPFFFA 190
Query: 223 TCVGVTIPVGFIAYGVLNITSTSVSLWKIFMMIIGACTFLLTILVLFIYPNNPTDAKFLN 282
C+G IP GFIAYGVL+IT+ S+SLWKIF +IIG TF++T++V+ +PNNP D KF +
Sbjct: 191 ACMGSPIPTGFIAYGVLHITNPSISLWKIFTIIIGGLTFIMTVVVILWFPNNPADVKFFS 250
Query: 283 TNEKVWVIRRVQQTTGSSIEQKVVKKHQIKEALLDPISWXXXXXXXXXXXXXXXPYQQTL 342
E+VW+IRRVQ +TGSSIEQKV KK Q +EA+ D I+W PYQQ L
Sbjct: 251 IQERVWIIRRVQASTGSSIEQKVFKKSQFREAMKDYITWLFGLFFLLQQLANNLPYQQNL 310
Query: 343 LFKSIGNISSLDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVVFWTIPSFVGSIAM 402
LF+ +G + +L STLVSVA GFAV C +AT L +KN +A + +FWT+P+ VGSIA
Sbjct: 311 LFEGMGGVDALGSTLVSVAGAGFAVVCAFIATLMLAKWKNISALTAIFWTLPALVGSIAA 370
Query: 403 VSIPFDKHIALLAMLCMASPAFGVPWILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANLI 462
++P+D I +LA +CMA FG+P+I+ SW S++ SGYTKKLTR+++ +F +AN+I
Sbjct: 371 AALPWDNKIGILANICMAGQIFGIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANII 430
Query: 463 SPQLWQEKDGPRYIPAWIVQIVLSFSIAPSIAIVIWYILRKRNQERAINLEAEEKKF--- 519
SPQ+W+EKD PR++PAWIVQIVLSFS+AP+I ++I +IL++RN +R N + + +
Sbjct: 431 SPQIWREKDSPRFLPAWIVQIVLSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDR 490
Query: 520 -GLIE-VNGESIKA--------NIAMLDLTDHENKTFIYPL 550
LIE N SI+ N+A+ DLTD EN+TFIYPL
Sbjct: 491 IQLIESENPSSIEEGKVVTHENNLAVFDLTDLENETFIYPL 531
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 424 bits (1090), Expect = e-118
Identities = 221/505 (43%), Positives = 319/505 (62%), Gaps = 12/505 (2%)
Query: 54 VSSRDADATLGFLEEFDPQVPAITAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYA 113
VS+ D T F++E P +T +Q+KRL K+ + ++ + ++++LY DKAT SY+
Sbjct: 52 VSNAVLDETFSFMQEAKDLEP-LTPKQDKRLRWKLYFTVLVMLMILDMMLYIDKATLSYS 110
Query: 114 SILGLWEEVGITQNQYNNSNTLFYVGFIVGQANLYFV-QTYPLKYVVSVMTALWTIVIFL 172
SILGL+E+ I NQYN+ NTLFYVGF++GQ + + Q +P+ V+ TALWTI+IFL
Sbjct: 111 SILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFPVSKFVAASTALWTIIIFL 170
Query: 173 HCACTNYRSFYVLRFFLGFVESVAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVG 232
HCA N+ LRFFLG VES +P + T+G F E+A P FY +C G IP G
Sbjct: 171 HCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNIPAG 230
Query: 233 FIAYGVLNITSTSVSLWKIFMMIIGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRR 292
FIAYGV +T +S WK+FM+I+G TF LTI + F YP+N + A+FL E+++ + R
Sbjct: 231 FIAYGVQYAKNT-ISPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDR 289
Query: 293 VQQTTGSSIEQKVVKKHQIKEALLDPISWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISS 352
V+++ S IE K KK+Q+ EAL DP++W YQQ LLF S+ N+S
Sbjct: 290 VRRSNHSGIESKTFKKYQVIEALKDPVTWLFTFHVFCNQLSNNLAYQQNLLFTSL-NVSD 348
Query: 353 LDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVVFWTIPSFVGSIAMVSIPFDKHIA 412
L+STLV VAS G+ I+AT + KN +AF W IPS G IA V++ +D I
Sbjct: 349 LNSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVAMSWDHKIG 408
Query: 413 LLAMLCMASPAFGVPWILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDG 472
LA + +AS FG+P+I+ W + +C+GYTKKLTR + M + +AN+I PQ+WQ +D
Sbjct: 409 ELAAIIIASN-FGIPFIISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDA 467
Query: 473 PRYIPAWIVQIVLSFSIAPSIAIVIWYILRKRNQERAINLEAEEKKF-----GLIEVNGE 527
PRY PAWIVQIV+++S++P + ++I +IL +RN++R LE ++++ I+ +G
Sbjct: 468 PRYYPAWIVQIVIAWSVSPFVLLIIRWILVRRNKKRLALLEQNKEQYEKTWIETIDSSGN 527
Query: 528 SIKA--NIAMLDLTDHENKTFIYPL 550
+ +MLDLTD EN +FIYPL
Sbjct: 528 HVSGFYENSMLDLTDQENLSFIYPL 552
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 416 bits (1069), Expect = e-116
Identities = 223/528 (42%), Positives = 322/528 (60%), Gaps = 19/528 (3%)
Query: 36 DSDDTELRDDKTKSKYAVVSSRDADATLGFLEEFDPQVPAITAEQEKRLSRKVTWIIVSL 95
DSD+ +K K +++ D T F+++ P +T +QE +L K+ ++ +
Sbjct: 49 DSDEDIADVEKAGGKK--INNSLIDETFAFMQDAKKLDP-LTPKQESKLKWKLYIYLLLM 105
Query: 96 TAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFYVGFIVGQ-ANLYFVQTYP 154
F++++L+ KAT SY++ILGL+++V IT NQYNN NTLFYVG+IVGQ Y +QT+P
Sbjct: 106 LGFLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGYIVGQFPGHYIMQTFP 165
Query: 155 LKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESVAIPCLNTTMGQFLTADEKA 214
L V ++T W++++FLHC NY LRFFLGF ES +P + TMG F T E+A
Sbjct: 166 LGKFVGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQA 225
Query: 215 ASAPMFYSTCVGVTIPVGFIAYGVLNITSTSVSLWKIFMMIIGACTFLLTILVLFIYPNN 274
P+F+ +C+ IP GFIAYG L + S++ WK+FM+I G TF L+I + F YP+N
Sbjct: 226 FLQPVFWISCLSCGIPAGFIAYG-LEFVTKSIAPWKLFMIITGGITFFLSIFLFFYYPDN 284
Query: 275 PTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQIKEALLDPISWXXXXXXXXXXXXX 334
P+ A+FL EK++ I RV+++T IE K+ KKHQ EAL DPI+W
Sbjct: 285 PSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQFIEALKDPITWLFTFAAFTLMLSN 344
Query: 335 XXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVVFWTIP 394
YQQ L+F S+ N+S L+STLV VA G+ I+AT + N +A+ +FW +P
Sbjct: 345 NLAYQQNLIFTSL-NVSDLNSTLVGVALAGYNTVSAIIATFAMYLIPNQSAYHAMFWMLP 403
Query: 395 SFVGSIAMVSIPFDKHIALLAMLCMASPAFGVPWILMFSWNSTTCSGYTKKLTRNAIVMF 454
S G IA V++P+ I LA + +AS FG+ +I+ W + T +GYTKKLTR + M
Sbjct: 404 SITGGIAFVALPWSNRIGELATMIIASD-FGITYIIALGWTTATSTGYTKKLTRGLMFMV 462
Query: 455 FFCVANLISPQLWQEKDGPRYIPAWIVQIVLSFSIAPSIAIVIWYILRKRNQERAI---- 510
+ +AN+ISPQLWQ +D PRY PAWIVQIV+++ + P I +V IL +RN++R
Sbjct: 463 GYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVTPIIYLVARVILARRNKQRKELKDK 522
Query: 511 -----NLEAEEKKF-GLIEVNGESIKANI--AMLDLTDHENKTFIYPL 550
+LE EK + ++ G +K I +MLDLTD EN F+YPL
Sbjct: 523 KIAEGSLETIEKTYVDTVDEFGNPVKVLIDNSMLDLTDMENLNFVYPL 570
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 194 bits (494), Expect = 2e-49
Identities = 133/475 (28%), Positives = 229/475 (48%), Gaps = 27/475 (5%)
Query: 79 EQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFYV 138
E ++ RKV I+ L+++ DKA +YA+ +G+ + + N+++N T+F
Sbjct: 69 ELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYAASMGIKDH--LKGNEFSNLGTIFSA 126
Query: 139 GFIVGQANL-YFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESV-A 196
+I + + Y +Q +P+ ++ +W IV+ H AC Y S V+R LG ES A
Sbjct: 127 AYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAACKTYASLMVVRTLLGLFESSSA 186
Query: 197 IPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVG-FIAYGVLNITSTSVSLWKIFMMI 255
+ C+ + G + T E++A F++T G VG I++G L+ T+ + W+I ++
Sbjct: 187 VGCIAIS-GMYYTKSEQSARIG-FWATQAGTGYIVGGLISFGFLHYHGTAFTSWQIMFLV 244
Query: 256 IGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQIKEAL 315
+G T +L P+N T+A FLN EK+ V+ ++ + +E K KK Q+KE
Sbjct: 245 VGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHIRANQ-TGLETKKFKKQQVKELF 303
Query: 316 L-DPISWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVACCILAT 374
L D +W ++ ++ L+ + G ++ T
Sbjct: 304 LHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYETALLQLPIGAITAMIILITT 363
Query: 375 TFLLYFKNYTAFSVVFWTIPSFVGSIAMVSIPFDKHIA-LLAMLCMASPAFGVPWILMFS 433
L + + T + + IP+ +G I ++S+P I L ++ + S + + I +
Sbjct: 364 QMLSRWGHITLITTSMY-IPAIIGCIVLISLPLSHKIGNLFSLYLLYSGSCVITNI--YI 420
Query: 434 WNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQIVLSFSIAPSI 493
WNS SGYTK++ RNAI M + V+ +I+PQ+++ PRYIPA I +V P +
Sbjct: 421 WNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAKIALLVTQCVCVP-L 479
Query: 494 AIVIWYILRKRNQERAINLEAEEKKFGLIEVNGESIKANIAMLDLTDHENKTFIY 548
+ I YI +K N++R E +E+K LDLTD EN+ F Y
Sbjct: 480 QLYIGYICKKENEKRDKEQEGQERK-------------KYQFLDLTDIENRNFRY 521
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 162 bits (410), Expect = 1e-39
Identities = 130/490 (26%), Positives = 225/490 (45%), Gaps = 30/490 (6%)
Query: 76 ITAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTL 135
+T E++++L K+ + + L + + + DK + S A+++GL ++ + +QY+ +
Sbjct: 69 VTPEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSA 128
Query: 136 FYVGFI---VGQANLYFVQTYPLKYVVSVMTALWTIVIFLHCACT-NYRSFYVLRFFLGF 191
FY G++ +G F +T + +++V +W +++ LH A T Y SF VLR LG
Sbjct: 129 FYFGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGC 188
Query: 192 VESVAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGV-LNITSTSVSLWK 250
ESV PC Q+ +E+ +++ +I + IAYGV ++ S ++ W+
Sbjct: 189 AESVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWR 248
Query: 251 IFMMIIGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQ 310
+I G T + IL+ P++P+ A+FL+ EK+ V++R++ +KK+Q
Sbjct: 249 TLFVITGVITIFIGILIFLWIPDDPSKARFLSKREKLMVVQRIRSNQ-QGFGNHEIKKYQ 307
Query: 311 IKEALLDPISWXXXXXXXXXXX--XXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVA 368
I EAL D +W + LL G SS ++ L+ + +G +
Sbjct: 308 IIEALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFG-YSSKETLLMGLPTGAVELV 366
Query: 369 CCILATTFLLYFKN-------YTAFSVVFWTIPSFVGSIAMVSIPFDKHIALL-AMLCMA 420
C L +Y N Y +F + + + S + K L A L
Sbjct: 367 GCPLFGILAVYAANKKIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYI 426
Query: 421 SPAFGVPWILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWI 480
SP V +I + S S SGY+KK T ++I + + ANL PQ + K P+Y A +
Sbjct: 427 SP---VSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKV 483
Query: 481 VQIVLSFSIAPSIAIVIWYILRKRNQERAINLEAEEKKFGLIEVNGESIKANIAMLDLTD 540
+V + ++I++ I+ R +R + AE G E N+ DLTD
Sbjct: 484 AMVVCYAVMIVLLSILL--IVNLRENKRRDKIAAER---GFPEET-----ENLEFSDLTD 533
Query: 541 HENKTFIYPL 550
EN F Y L
Sbjct: 534 FENPNFRYTL 543
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 160 bits (405), Expect = 5e-39
Identities = 132/477 (27%), Positives = 216/477 (44%), Gaps = 23/477 (4%)
Query: 77 TAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLF 136
TA++ +R+ K+ +++ + +I Y DK SYA++ G+ + I + Y++ TLF
Sbjct: 62 TAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMKTDTHIDGHTYSSMTTLF 121
Query: 137 YVGFIVGQ-ANLYFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESV 195
Y G++V Q +Q L Y + LW+ ++ L AC N S LRF G E+
Sbjct: 122 YAGYLVAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLAGIFEAS 181
Query: 196 AIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLNITSTSVSLWKIFMMI 255
P + +E+ +Y+ I ++YG+ +I V+ W+ ++
Sbjct: 182 ITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGLGHIHG-KVASWRYVFIV 240
Query: 256 IGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQIKEAL 315
IG + ++ +FI P+NP+ A+FL++ EK + RV+ + +E K K EA
Sbjct: 241 IGLMSLGWGVVFVFI-PSNPSKARFLSSREKRIALERVRDNR-TGLENKQFKWKHAYEAF 298
Query: 316 LDPISWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVACCILATT 375
LDP TL+ K +G + L S ++++ G VA ++
Sbjct: 299 LDPQVIMITLFTGVCMITNGIGVFSTLIIKGLG-YNELHSAVLNMPLGAIEVAAMFISGV 357
Query: 376 FLLYFKNYTAFSVVFWTIPSFVGSIAMVSIPFDKHIALL--AMLCMASPAFGVPWILMFS 433
FKN VF + G + + IP L M PA L+ S
Sbjct: 358 LCKVFKNGRLLIGVFMNCLTLAGCLMIWKIPDSNPYGRLVGVWFTMWVPASSA---LLLS 414
Query: 434 WNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQIVLSFSIAPSI 493
S+ +GYTKK +A V F+ V N++SPQL++ P YI I +++S I +I
Sbjct: 415 LISSNVAGYTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIEG-IQAMIVSLCIIIAI 473
Query: 494 AIVI--WYILRKRNQERAINLEAEEKKFGLIEVNGESIKANIAMLDLTDHENKTFIY 548
A V+ +YI + ++R L AE+ GESIK N +DLTD + F Y
Sbjct: 474 AFVLTGYYIYENKRRDR---LLAEDPSL------GESIK-NEEFMDLTDRQQPKFRY 520
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 159 bits (403), Expect = 8e-39
Identities = 143/521 (27%), Positives = 224/521 (42%), Gaps = 33/521 (6%)
Query: 44 DDKTKSKYAVVSSRDADATLGFLEE----------FDPQVPAITAEQEKRLSRKVTWIIV 93
D+K K +V + D +G L D I E E+RL RK+ I
Sbjct: 7 DEKLKDPESVQNKEILDVDVGDLSPKGVDAAFNYALDVDYDEIDPETERRLVRKIDCTIF 66
Query: 94 SLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFYVGFIVGQ--ANLYFVQ 151
+ + I + DK + SYA I+GL E++ + Y+ S T FY+G++V + A+L +Q
Sbjct: 67 PVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLVFEFPASL-LLQ 125
Query: 152 TYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESVAIPCLNTTMGQFLTAD 211
+PL + V +W ++ + + NY F LR LG +ES A P Q+
Sbjct: 126 RFPLSKTLCVFLVIWGFLLCM-TSVANYPGFIALRVLLGMMESAASPGFILLTAQWYKRS 184
Query: 212 EKAASAPMFYSTCVGVTIPVGFIAYGVLNITSTSVSLWKIFMMIIGACTFLLTILVLFIY 271
E+ ++ + I +AYG+ TS + WK+ +I G L ++L +
Sbjct: 185 EQQLRTSVWVAFNGLGQILGSCMAYGLAKRTSLPMRGWKLIFIICGVLAIFLGFVILAVV 244
Query: 272 PNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQIKEALLDPISWXXXXXXXXXX 331
P+NP A FL ++ V++R++ + K +Q KE +LD +W
Sbjct: 245 PDNPFKAWFLTEEDRKLVVKRLRANK-QGVGNNHFKLYQFKETMLDIRTWIMFVSSVLLN 303
Query: 332 X-XXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVVF 390
+LL K +L + L+ + +G ++A FL F +
Sbjct: 304 IPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGG-LIAFGFLSLFIHKRMVLATI 362
Query: 391 WTIPSFVGSIAMVSIPFDKHIALLAM-LCMASPAFGVPWILMFSWNSTTCSGYTKKLTRN 449
T + +GS ++S L L M SP I+MF+ S+ SGYTKK+T
Sbjct: 363 TTCIALIGS-CLLSFAGPPRAQLAGYYLLMVSPG---AMIVMFAIISSNASGYTKKVTVG 418
Query: 450 AIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQIVLSFSIAPSIAIVIWYILRKRNQERA 509
I + +CV NLI PQ ++ D P Y+PA ++ A + Y + R +R
Sbjct: 419 VIYLIGYCVGNLIGPQTFKAADAPEYMPA--KNTMVGCYAATLVTFPALYYVNWRENKRR 476
Query: 510 INLEAEEKKFGLIEVNGESIKANIAMLDLTDHENKTFIYPL 550
L AE G IE + N DLTD EN F Y L
Sbjct: 477 DQLAAE----GKIE-----HRPNAEFEDLTDFENLDFRYTL 508
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 149 bits (375), Expect = 1e-35
Identities = 130/501 (25%), Positives = 225/501 (43%), Gaps = 51/501 (10%)
Query: 69 FDPQVPAITAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQ 128
F + P I ++L K ++ L I+ Y DK+T++Y+SI+G+ ++ + NQ
Sbjct: 29 FAEKHPIIDKSLNRKLKLKTDLWVMPLLCLISAFQYMDKSTSNYSSIMGIRTDLNMVGNQ 88
Query: 129 YNNSNTLFYVGFIVGQANL-YFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRF 187
YN T FY+GF+V L +Q +PL V S W I++ L C +Y S+ R
Sbjct: 89 YNWVGTSFYLGFMVFSLPLSTLLQKFPLSKVTSAFIVAWGILMTLTCLVHSYASYIATRT 148
Query: 188 FLGFVESVAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLN---ITST 244
LG +ESV P + Q+ +E+ + + G ++YG+ +
Sbjct: 149 LLGILESVITPAFVLFIAQWYRKEEQFFRMAFLVAWNGLGGLIGGSMSYGLYKRELENNL 208
Query: 245 SVSLWKIFMMIIGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQK 304
++S W+I +I G T + + + P+ P+ A FL+ EK V++R+ T + + K
Sbjct: 209 TMSPWRILFIITGLITIINGVFIFIHIPDEPSKAWFLSEKEKDLVLKRL-DTDHAGLGSK 267
Query: 305 VVKKHQIKEALLDPISWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGG 364
KK+QI EA D + + Q + G +S+ S ++
Sbjct: 268 KFKKYQILEACRDVRMYLYF-------------FLQIAVAIPNGGLSNFSSIMLKNLGYV 314
Query: 365 FAVACCILATTFLLYFKNYTAFSVVFWTIPSFVG---SIAMVSIPFDKHIALLAMLCMAS 421
A + T + F T F + IP F IA+V + ++ +++ A
Sbjct: 315 KGKALLMNMPTSSISFAALTLFGL----IPEFTNRRMDIALVGLAI--NLTSGSLIAFAK 368
Query: 422 PA---------FG---VPWILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQE 469
P FG +P+I + S S+ +G+TKK+ +A+ M +CV N++ PQ ++
Sbjct: 369 PTHAQLAGYWLFGISPIPYICILSCISSNSAGHTKKVFMSAVSMIGYCVGNMVGPQTFRS 428
Query: 470 KDGPRYIPAWIVQIVLSFSIAPSIAIVIWYILRKRNQERAINLEAEEKKFGLIEVNGESI 529
P+Y A V V+ + +A I I I+ + + N+ R E+ ++ E++ E
Sbjct: 429 TQAPKYQGA-KVSFVVCYCVAIFIIIAIYAVNVRENRRR-----DEKNEYLSNELSEEDK 482
Query: 530 KANIAMLDLTDHENKTFIYPL 550
K DLTD EN F Y +
Sbjct: 483 K------DLTDFENPEFRYSI 497
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 116 bits (290), Expect = 1e-25
Identities = 96/451 (21%), Positives = 193/451 (42%), Gaps = 11/451 (2%)
Query: 67 EEFDPQVPAITAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQ 126
E+ +V + + E+RL RK + I+ L A + L DK+ S A G+ +++G
Sbjct: 36 EDVTTEVYILDHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVG 95
Query: 127 NQYNNSNTLFYVGFIVGQANL-YFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVL 185
+QYN ++FY+ F++ Y + + ++ + + A N+ +
Sbjct: 96 DQYNIMISIFYIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAV 155
Query: 186 RFFLGFVESVAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLNITSTS 245
R+FLG ES +P + + F E A +FY+ + G +AYGV +I
Sbjct: 156 RWFLGMAESAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKGGK 215
Query: 246 VSLWKIFMMIIGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKV 305
+ W+ +I G TFL I++ + P + A FL EK R++ + S+I +K+
Sbjct: 216 LQGWQYLFLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKL 275
Query: 306 VKKHQIKEALLDPIS--WXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLDSTLVSVASG 363
K + PI+ W + ++ + SS+++ L++VA
Sbjct: 276 SFKQSL-TVFKHPIAILWLLEEMALGVPLNSINNWLPQIV--AAMGFSSVNTNLMTVAP- 331
Query: 364 GFAVACCILATTFLLYFKNYTAFSVVFWTIPSFVGSIAMVSIPFDKHIALLAMLC-MASP 422
+ A +L F+ F ++ + +G I SI HI + C + +
Sbjct: 332 AISGAIWLLVFAFISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTA 391
Query: 423 AFGVPWILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQ 482
+L +W + +++ ++ + V L+S +++ +D P+Y+PA +
Sbjct: 392 GAAASSVLTSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGIT 451
Query: 483 I---VLSFSIAPSIAIVIWYILRKRNQERAI 510
L + SI++ +++ R+R+ + +
Sbjct: 452 AGFGGLGILLVASISVYMFFDNRRRDNAQGV 482
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 90.9 bits (224), Expect = 5e-18
Identities = 56/222 (25%), Positives = 107/222 (47%), Gaps = 2/222 (0%)
Query: 76 ITAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTL 135
I ++E +L RK+ W ++ + + + + + D+A A+++GL E++ + QY+ + ++
Sbjct: 28 IEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVSV 87
Query: 136 FYVGFIVGQA-NLYFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVES 194
FY +I + ++ V+ + Y +S M W++V C +Y S + R LG E
Sbjct: 88 FYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGICEG 147
Query: 195 VAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLNI-TSTSVSLWKIFM 253
PCL+ + +E+ Y G IA G+ I S+ + W
Sbjct: 148 GFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGWLY 207
Query: 254 MIIGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQ 295
+I G + + + +LF P++P+ A+FLN EK + R +Q
Sbjct: 208 IIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQ 249
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 88.6 bits (218), Expect = 2e-17
Identities = 107/493 (21%), Positives = 187/493 (37%), Gaps = 48/493 (9%)
Query: 35 EDSDDTELRDDKTKSKYAVVSSRDADATLGFLEEFDPQVPAITAEQEKRLSRKVTWIIVS 94
++ D L + K + + R+ AT D +P+ + EKR+ RK+ ++
Sbjct: 39 DEGHDASLHNRSHDKKSELATEREIMATT----TDDDGIPSPSHPMEKRVLRKMDIYLIP 94
Query: 95 LTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFYVGFIVGQ---ANLYFVQ 151
L + + DK+ A + GL +++ + QYN T+F+ +++ NL +
Sbjct: 95 LMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVLFDPIGTNLLKIM 154
Query: 152 TYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESVAIPCLNTTMGQFLTAD 211
PL ++S+ + + NY V+R LG E + P +N + +
Sbjct: 155 GPPL--MMSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRRE 212
Query: 212 EKAAS-APMFYSTCVGVTIPVGFIAYGVLNITSTSVSLWKIFMMIIGACTFLLTILVLFI 270
+ A A +F + C+ + G IAYG I S S+ W+ ++ G + F
Sbjct: 213 QYALRFAFVFSAACLSSSFG-GLIAYGCSKI-SGSLKDWQYIYIVEGCISLGFVPFYAFG 270
Query: 271 YPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQIKEALLDPISWXXXXXXXXX 330
N D+ F N EK ++ R + ++K + Q+ +A+ D +W
Sbjct: 271 LSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEK-FEWFQVWQAVKDVKTWASAVALFGI 329
Query: 331 XXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVVF 390
+ T+ I + S GF L T + + F
Sbjct: 330 DLTT---FGLTVFLPII------------ITSMGFTNVRAQLMTVPIYFLTAIVFFICAV 374
Query: 391 WT------IPSFVGSIAMVSIPFDKHIALLAMLCMASPAFGVPWILM---------FSWN 435
W+ P +G+ SI +L FGV + M W
Sbjct: 375 WSDRIKLRSPFILGACLTTSIGI---AIVLGSQVHGVRYFGVYILCMGIYVNAACNCLWL 431
Query: 436 STTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQIVLSFSIAPSIAI 495
S Y K+ T I +FF + L+S Q++ KD PRYI + I L+F +
Sbjct: 432 SGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKG--LSISLAFQVFSIFMT 489
Query: 496 VIWYILRKRNQER 508
V+ L KR ++
Sbjct: 490 VVQIFLYKRENDK 502
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 86.7 bits (213), Expect = 9e-17
Identities = 104/485 (21%), Positives = 201/485 (41%), Gaps = 69/485 (14%)
Query: 81 EKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFYVGF 140
E++L K+ W I+S I Y D+++ + A + G+ E++ + N+ + N +F G+
Sbjct: 21 EQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCGY 80
Query: 141 IVGQ-ANLYFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESVAIPC 199
I+GQ Y +Q P + SVM LW ++ A + R+ +LRFF+ E+
Sbjct: 81 IIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTFAG 140
Query: 200 LNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLNITS--TSVSLWKIFMMIIG 257
+ +G + E A +F ++ + T+ G++ V + + +S W+ +I G
Sbjct: 141 THYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFIIDG 200
Query: 258 ACTFLLTILVLFIYPNNP--TDAKFLNTNEKVWVIRRV------QQTTGSSIEQKVVKKH 309
T L++ LF++P+ P T A + EK +R+ + T +I+ +V+
Sbjct: 201 ILTIPLSLYGLFLFPDVPETTKAPYFTEQEKELSFKRLPARPKKKPLTLKAIKD-IVRSW 259
Query: 310 QI------------KEALLDPI---SWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLD 354
+I +A+ + W P + ++G +S+L
Sbjct: 260 RIYGLCILWIFSGETQAIAVNVLMGQWMKWSNKFSVAQINNYP----TVITAVGVVSTLG 315
Query: 355 STLVSVASGG-----FAVACCILATTFLLYFKNYTAFSVVFWTIPSFVGSIAMVSIPFDK 409
++++S G F + C++ T +A ++ W +P K
Sbjct: 316 ASVISDKLAGNPRWPFGLFLCVITTV--------SATILLAWNVPDGA-----------K 356
Query: 410 HIALLAMLCMASPAFGVPWILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANL----ISPQ 465
A A C + A W FSW + C ++ R +V N+ +P
Sbjct: 357 FFAYFASGC--TYAGQAVW---FSWANDICRDNDQE--RGVVVFLMNMCQNIWHIWWAPI 409
Query: 466 LWQEKDGPRYIPAWIVQIVLSFSIAPSIAIVIWYILRKRNQERAINLEAEEKKFGLIEVN 525
++ D PR+I I +V+ + S IV + +R + +R+I + K F +
Sbjct: 410 MYPNTDTPRFIKGLIGLLVVGGIVFVSSCIVSYMQIRDKRIKRSIQ---DAKDFDDVFTE 466
Query: 526 GESIK 530
ES++
Sbjct: 467 HESLE 471
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 83.2 bits (204), Expect = 9e-16
Identities = 90/487 (18%), Positives = 207/487 (42%), Gaps = 35/487 (7%)
Query: 34 SEDSDDTELRDDKTKSKYAVVSSRDADATLGFLEEFDPQVPAITAEQEKRLSRKVTWIIV 93
S+D + + + K K +S D D + DP+V EK+L K+ +I
Sbjct: 10 SKDDEHSIYASEINKEKLQNTASPDVDYGDTASLKIDPKV-------EKKLLLKMDLVIS 62
Query: 94 SLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFYVGFIVGQA-NLYFVQT 152
+ F+ L+ + D++ A++ G+ E + + + N + ++FYV +I+ + ++ V+
Sbjct: 63 PIIGFLYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYILVETPSVVLVKR 122
Query: 153 YPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESVAIPCLNTTMGQFLTADE 212
+++ ++ W++ + ++Y R LG +E P LN + T E
Sbjct: 123 IKASRMLAFISFAWSMTVLFSGFMSSYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKE 182
Query: 213 KAASAPMFYSTCVGVTIPVGFIAYGVLNITSTSVSLWKIFMMIIGACTFLLTILVLFIYP 272
+ +++ G AY + + + + W+ ++ G +F+ L LF P
Sbjct: 183 QCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVEGLVSFIGVPLCLFALP 242
Query: 273 NNPTDAKFLNTNEK-VWVIRRVQQTTGSSIEQKVVKKHQIKEALLDP-ISWXXXXXXXXX 330
+ +A FL E+ V +IRR ++ + ++++A DP +
Sbjct: 243 DKMENAWFLTREEREVAIIRR--DINARYHGEQHFEWSEVRKAFKDPKVYVSATSQFCAD 300
Query: 331 XXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVVF 390
++ K +G + L + +++ +++ F+ + + T V+
Sbjct: 301 MVLYGFSSFLPVIIKGLGFV-GLQTNYMTIP----VYIAGVISFLFVAWLSDRTQLRAVY 355
Query: 391 WTIPSFVGSIA-MVSIPFDKHIA------LLAMLCMASPAFGVPWILMFSWNSTTCSGYT 443
S V ++ ++ + D + A ++A+ C P + W+ + +G+
Sbjct: 356 LISASTVVAVGYIIMLASDSNAAKYTATYIIAIGCYIGPGLNLGWL------NNNVAGHY 409
Query: 444 KKLTRNAIVMFFFCVANLISPQLWQEKDGPRYI--PAWIVQIVLSFSIAPSIAIVIWYIL 501
K+ T I + +++ Q+++ K+ P+YI A+ + V+ +A +V+++ L
Sbjct: 410 KRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTLGCVIVGGLA---YVVMFFSL 466
Query: 502 RKRNQER 508
R N++R
Sbjct: 467 RYVNKKR 473
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 76.6 bits (187), Expect = 9e-14
Identities = 91/445 (20%), Positives = 184/445 (40%), Gaps = 20/445 (4%)
Query: 76 ITAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTL 135
+T + L ++ ++ + L+ + D++ A + GL E++ + +Q+N ++
Sbjct: 43 LTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNIIASV 102
Query: 136 FYVGFIVGQ--ANLYFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVE 193
FYV FI+ + L + P + + ++ + IF C N+ R LGF E
Sbjct: 103 FYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTG-FCHNFGGLLAARLVLGFCE 161
Query: 194 SVAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLNITST-SVSLWKIF 252
+ PCL + + E A +++ G AY VL++ + W+
Sbjct: 162 AGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMDGVGGFAGWRWL 221
Query: 253 MMIIGACTFLLTILVLFIYPNNPTDAKFLNTNEKVWVIRRVQQTTGSSIEQKVVKKHQIK 312
+I G F+ + V FI PN+ T A FL+ + ++R+ Q + +E +K
Sbjct: 222 FIIEGLIGFVCGVAVYFIIPNDITKAWFLSKTHQE-MMRKRQLERAADLEAAHFDWKGVK 280
Query: 313 EALLDPISWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAV----A 368
A D + Y + +I IS + T +SV V A
Sbjct: 281 SAFTD---FKVYLYALSEFGQDTCLYGFSTFLPAI--ISGMGYTSLSVQYMTIPVYILGA 335
Query: 369 CCILATTFLLYFKNYTAFSVVFWTIPSFVGSIAMVSIPFDKHIALLA-MLCMASPAFGVP 427
+A +FL ++ ++ I VG I +++ +K + A LC G
Sbjct: 336 ATYIAASFLSDRFHHRGIILIIGNIFPIVGYILLLACQNNKSVLYFACYLCSVGVYTGAG 395
Query: 428 WILMFSWNSTTCSGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQIVLSF 487
L +W S + + K+ T ++ + + +++ Q+++ P+YI + ++ F
Sbjct: 396 --LNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYRYP--PKYIAGHLTSLIAIF 451
Query: 488 SIAPSIAIVIWYILRKRNQERAINL 512
I+ + +V + L+ +N ++ +L
Sbjct: 452 -ISTVLHVVNIFFLKHQNSKKQKSL 475
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 68.9 bits (167), Expect = 2e-11
Identities = 98/486 (20%), Positives = 192/486 (39%), Gaps = 43/486 (8%)
Query: 66 LEEFDPQVPAITAEQEKRLSRKVT-----WIIVSLTAFINLILYSDKATASYASILGLWE 120
L +FDP+ T ++EK+L RK+ W+ + + AF++LI + S I+ L
Sbjct: 56 LSKFDPEF-TWTKDEEKKLVRKMDLKIFLWVFI-MFAFLDLIRKNIARAVSDNFIVDL-- 111
Query: 121 EVGITQNQYNNSNTLFYVGFIVGQ--ANLYFVQTYPLKYVVSVMTALWTIVIFLHCACTN 178
+ N YN T++ V F+ + NL + P + V+ V LW+++ N
Sbjct: 112 --KMNTNDYNLGQTVYLVIFLASELPGNLLSKRFGPER-VIPVQIVLWSVICITQAGLKN 168
Query: 179 YRSFYVLRFFLGFVESVAIPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGV 238
F R LG V+ IP + + T E F+ I +A G+
Sbjct: 169 RGQFIATRCLLGMVQGGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGI 228
Query: 239 LNITST-SVSLWKIFMMIIGACTFLLTILVLFIYPNNPTD----------AKFLNTNEKV 287
+ + +++ W+ +I G + + + ++ PT + F EK+
Sbjct: 229 IEMRGIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKI 288
Query: 288 WVIR--RVQQTTGSSIEQKVVKKHQIKEALLDPISWXXXXXXXXXXXXXXXPYQQ-TLLF 344
V R R + G ++ V +I L + W +L+
Sbjct: 289 MVNRILRDDPSKGDMSNRQPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLIL 348
Query: 345 KSIGNISSLDSTLVSVASGGFAVACCILATTFLLYFKNYTAFSVV--FWTIPSFVGSIAM 402
KS+ N S+ S ++++ + LA K + + W +P V +A+
Sbjct: 349 KSL-NYSTFLSNILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVAL 407
Query: 403 VSI--PFDKHIALLAMLCMASPAFGVPWI--LMFSWNSTTCSGYTKKLTRNAIVMFFFCV 458
+ P+ K+I L +L G+P+ ++ W S + + A+ V
Sbjct: 408 PTDTNPWIKYILLTGIL-------GLPYTHSILAGWVSEISNSVRSRTVGTALYNMSAQV 460
Query: 459 ANLISPQLWQEKDGPRYIPAWIVQIVLS-FSIAPSIAIVIWYILRKRNQERAINLEAEEK 517
+I+ +++ D P Y + + + F+I ++A +YI R + ++R N +E+
Sbjct: 461 GAIIASNMYRNDDKPYYTRGNKILLGFTCFNICMAVATKFYYISRNKYKDRKWNSMTKEE 520
Query: 518 KFGLIE 523
+ ++
Sbjct: 521 QINYLD 526
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 63.2 bits (152), Expect = 1e-09
Identities = 84/467 (17%), Positives = 186/467 (38%), Gaps = 18/467 (3%)
Query: 77 TAEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLF 136
T+ +EK+L K+ ++ + + Y D + A + G+ E++G N ++ ++
Sbjct: 124 TSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMY 183
Query: 137 YVGFIVGQAN-LYFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESV 195
VG I+ Q L ++ PL YV+ + W+++ + +RFF+G E+
Sbjct: 184 TVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAP 243
Query: 196 AIPCLNTTMGQFLTADEKAASAPMFY-STCVGVTIPVGF--IAYGVLNITSTSVSLWKIF 252
+ G F DE + +Y +G+ G Y LN + + W+
Sbjct: 244 SYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVN-GLEGWRWN 302
Query: 253 MMIIGACTFLLTILVLFIYPNNPTDA-KFLNTNEKVWVIR---RVQQTTGSSIEQKVVKK 308
+I + ++ ++ + P +P + T++++ + R + QT S E KV
Sbjct: 303 FIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFDI 362
Query: 309 HQIKEALLD-PISWXXXXXXXXXXXXXXXPYQQTLLFKSIGNISSLDSTLVSVASGGFAV 367
K D I L KS+ S +S+ + G +
Sbjct: 363 KLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLKRYSIPKLNQLSMITPGLGM 422
Query: 368 ACCILATTFLLYFKNYTA-FSVVFWTIPSFVGSIAMVSIPFDKHIALLAMLCMASPAFGV 426
+L T ++ K ++ F+++F + + +G+ + + + A +
Sbjct: 423 VYLML--TGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFMLQCFGWAMA 480
Query: 427 PWILMFSWNSTTC--SGYTKKLTRNAIVMFFFCVANLISPQLWQEKDGPRYIPAWIVQIV 484
P +++SW + C T+ +T + + IS +W+ ++ PRY+ +
Sbjct: 481 P--VLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKGFTFTAC 538
Query: 485 LSFSIAPSIAIVIWYILR-KRNQERAINLEAEEKKFGLIEVNGESIK 530
+F ++ +V+++ R +RN + + K G+ + + ++
Sbjct: 539 SAFCLSIWTFVVLYFYKRDERNNAKKNGIVLYNSKHGVEKPTSKDVE 585
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 53.9 bits (128), Expect = 6e-07
Identities = 43/201 (21%), Positives = 85/201 (41%), Gaps = 3/201 (1%)
Query: 78 AEQEKRLSRKVTWIIVSLTAFINLILYSDKATASYASILGLWEEVGITQNQYNNSNTLFY 137
A +++ L K+ ++S I Y D+ + A I G+ E++ + N SNT+F
Sbjct: 23 AIKKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFM 82
Query: 138 VGFIVGQA-NLYFVQTYPLKYVVSVMTALWTIVIFLHCACTNYRSFYVLRFFLGFVESVA 196
+G+IVG N + P + +S T W ++ T+++ +RFF ES
Sbjct: 83 IGYIVGMVPNNLMLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCT 142
Query: 197 IPCLNTTMGQFLTADEKAASAPMFYSTCVGVTIPVGFIAYGVLNITS--TSVSLWKIFMM 254
+ +G + DE + +F + + ++ GF+ + + ++ W+ +
Sbjct: 143 FSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFI 202
Query: 255 IIGACTFLLTILVLFIYPNNP 275
I T + I +P P
Sbjct: 203 IDFCITLPIAIYGFIFFPGLP 223
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.324 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,067,078
Number of Sequences: 60738
Number of extensions: 1201982
Number of successful extensions: 4362
Number of sequences better than 1.0e-05: 17
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4302
Number of HSP's gapped (non-prelim): 22
length of query: 550
length of database: 30,389,216
effective HSP length: 111
effective length of query: 439
effective length of database: 23,647,298
effective search space: 10381163822
effective search space used: 10381163822
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)