ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4773 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4773 1689555 1691087 511
(511 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 437 e-122
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 347 2e-95
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 328 1e-89
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 265 2e-70
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 169 7e-42
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 137 4e-32
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 127 4e-29
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 123 7e-28
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 118 2e-26
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 105 2e-22
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 102 1e-21
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 96 2e-19
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 93 8e-19
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 86 1e-16
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 84 4e-16
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 82 1e-15
SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superf... 75 2e-13
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 70 1e-11
YGR065c [G] KOG2533 Permease of the major facilitator superfamily 67 8e-11
YOL163w [G] KOG2533 Permease of the major facilitator superfamily 57 5e-08
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 54 4e-07
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 437 bits (1124), Expect = e-122
Identities = 218/460 (47%), Positives = 296/460 (63%), Gaps = 1/460 (0%)
Query: 52 ENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSN 111
+++ I+ KEEA VRKLD L+PM + +YFLS LDR+NIGNA G++EDL+L + QYS
Sbjct: 24 DDITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSA 83
Query: 112 AVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLG 171
AVSVFY+TY+ AE YY+S +++ WS++T+ FV+ Y SL+ R+LLG
Sbjct: 84 AVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLG 143
Query: 172 AFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEGW 231
EGGFFP ++L IS+ YK++EQGKR TGL + + GL W
Sbjct: 144 ICEGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNW 203
Query: 232 RWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGRFEWSY 291
WLYIIEGLIS +++W+ LP D +L+ RE E++KIRA+QR YMG F+W+
Sbjct: 204 GWLYIIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWTQ 263
Query: 292 VFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVYILAAIV 351
A KD K Y+S IQFCQD++LYG STF+ +ILKL LGY+S AQYMSVPVY L I
Sbjct: 264 FRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGIS 323
Query: 352 FLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFSLYTGTGLNI 411
+ +SDR +R + N G G+I+LL+ N++ Y A YLI LY LNI
Sbjct: 324 VYVICLLSDRTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNI 383
Query: 412 AWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIYTTAPYTFGHSFSLGCIVLSNLLAIT 471
W+ NN+APHY+RATALG NQT+GN++G +AGQ+Y ++PY GH F+LGC V+ L A
Sbjct: 384 TWINNNMAPHYRRATALGCNQTIGNLAGVIAGQVYRSSPYKLGHGFALGCTVVGTLTATA 443
Query: 472 QMFILKRINRKRQRILSGEISDDHRGVRNGDNALDFKYCM 511
F L+R N+ +Q IL+GE D+ + R+G +ALDF Y +
Sbjct: 444 MRFYLQRQNKIKQEILNGERVDEKK-ERDGCDALDFVYVL 482
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 347 bits (891), Expect = 2e-95
Identities = 192/487 (39%), Positives = 275/487 (56%), Gaps = 21/487 (4%)
Query: 38 SIASFSIEQESLENE-----------NLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLD 86
SI + I +E L+N +L+IDPK E + K+D + P++ F+Y ++ LD
Sbjct: 16 SIYASEINKEKLQNTASPDVDYGDTASLKIDPKVEKKLLLKMDLVISPIIGFLYLMAFLD 75
Query: 87 RSNIGNAYTSGMREDLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLS 146
RSNIGNA +GM E L L ++ + AVS+FY Y+ E ++F+ +
Sbjct: 76 RSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYILVETPSVVLVKRIKASRMLAFISFA 135
Query: 147 WSIITLCNAFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXX 206
WS+ L + F+ SY LIA R++LG EG FPA+ L ++ Y ++EQ +R
Sbjct: 136 WSMTVLFSGFMSSYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAG 195
Query: 207 XXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSAR 266
L + AG EGW+W+YI+EGL+S LP +N +L+
Sbjct: 196 LAGAFGGLFAYALEQVH-AGNKEGWQWIYIVEGLVSFIGVPLCLFALPDKMENAWFLTRE 254
Query: 267 ETEILKIRAKQRVAYMGDGRFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAIL 326
E E+ IR Y G+ FEWS V A KD K Y+S T QFC D++LYGFS+F+ I+
Sbjct: 255 EREVAIIRRDINARYHGEQHFEWSEVRKAFKDPKVYVSATSQFCADMVLYGFSSFLPVII 314
Query: 327 KLGLGYTSREAQYMSVPVYILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSV 386
K GLG+ + YM++PVYI I FL A++SDR ++RA + + + AVGYI++L+
Sbjct: 315 K-GLGFVGLQTNYMTIPVYIAGVISFLFVAWLSDRTQLRAVYLISASTVVAVGYIIMLAS 373
Query: 387 HNNSVKYFACYLITFSLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIY 446
+N+ KY A Y+I Y G GLN+ WL NNVA HYKRATA+G+ QTL N SG VAGQIY
Sbjct: 374 DSNAAKYTATYIIAIGCYIGPGLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIVAGQIY 433
Query: 447 TT--AP-YTFGHSFSLGCIVLSNLLAITQMFILKRINRKR-QRILSGEISDDHRGVRNGD 502
+ AP Y G++F+LGC+++ L + F L+ +N+KR +R GE GD
Sbjct: 434 RSKNAPKYILGNAFTLGCVIVGGLAYVVMFFSLRYVNKKRDERCARGEFDPS----AIGD 489
Query: 503 NALDFKY 509
A DF+Y
Sbjct: 490 FADDFRY 496
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 328 bits (841), Expect = 1e-89
Identities = 179/479 (37%), Positives = 259/479 (53%), Gaps = 3/479 (0%)
Query: 35 ESGSIASFSIEQESLENENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAY 94
ES + S S + EN + E + + +LD L P + +Y ++ LDRSNIGNA
Sbjct: 22 ESEKVISRSNTASPISIENTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAK 81
Query: 95 TSGMREDLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCN 154
+G+ EDL+L Q++ SVFY T++ E ++F+V+S+S+ T+
Sbjct: 82 VAGLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFT 141
Query: 155 AFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXX 214
F ++ L+A R++LG E G FP + L ++++Y + E R
Sbjct: 142 GFCHNFGGLLAARLVLGFCEAGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGL 201
Query: 215 XXTGLASMKPAGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIR 274
+ M GG GWRWL+IIEGLI V ++ +P D +LS E+++ R
Sbjct: 202 FAYAVLHMDGVGGFAGWRWLFIIEGLIGFVCGVAVYFIIPNDITKAWFLSKTHQEMMRKR 261
Query: 275 AKQRVAYMGDGRFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTS 334
+R A + F+W V A DFK Y+ +F QD LYGFSTF+ AI+ G+GYTS
Sbjct: 262 QLERAADLEAAHFDWKGVKSAFTDFKVYLYALSEFGQDTCLYGFSTFLPAIIS-GMGYTS 320
Query: 335 REAQYMSVPVYILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVHNN-SVKY 393
QYM++PVYIL A ++ ++++SDR R I + N+ VGYILLL+ NN SV Y
Sbjct: 321 LSVQYMTIPVYILGAATYIAASFLSDRFHHRGIILIIGNIFPIVGYILLLACQNNKSVLY 380
Query: 394 FACYLITFSLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIYTTAP-YT 452
FACYL + +YTG GLN+ WL+ N+APHYKRATA+ L + N SG +AGQIY P Y
Sbjct: 381 FACYLCSVGVYTGAGLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYRYPPKYI 440
Query: 453 FGHSFSLGCIVLSNLLAITQMFILKRINRKRQRILSGEISDDHRGVRNGDNALDFKYCM 511
GH SL I +S +L + +F LK N K+Q+ L+ + D D F Y +
Sbjct: 441 AGHLTSLIAIFISTVLHVVNIFFLKHQNSKKQKSLASSSTIDLSEQPKDDKDARFHYIL 499
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 265 bits (676), Expect = 2e-70
Identities = 145/430 (33%), Positives = 238/430 (54%), Gaps = 6/430 (1%)
Query: 61 EAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYSTY 120
E +RK+D L+P++ +YFLS+LD+SNIGNA +G+ +D+ L QY+ V+VF++TY
Sbjct: 81 EKRVLRKMDIYLIPLMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATY 140
Query: 121 LAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFFPA 180
+ + MS + + I+L A+V++YA LI +R+LLGAFEG +PA
Sbjct: 141 VLFDPIGTNLLKIMGPPLMMSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPA 200
Query: 181 MTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEGL 240
+ + +S+ Y++++ R G + K +G L+ W+++YI+EG
Sbjct: 201 INMYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYGCS--KISGSLKDWQYIYIVEGC 258
Query: 241 ISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGRFEWSYVFDALKDFK 300
IS+ + L K+ ++ + + E E + R K + D +FEW V+ A+KD K
Sbjct: 259 ISLGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFEWFQVWQAVKDVK 318
Query: 301 TYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVYILAAIVFLISAYISD 360
T+ S F D+ +G + F+ I+ +G+T+ AQ M+VP+Y L AIVF I A SD
Sbjct: 319 TWASAVALFGIDLTTFGLTVFLPIIIT-SMGFTNVRAQLMTVPIYFLTAIVFFICAVWSD 377
Query: 361 RLKVRAPIFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFSLYTGTGLNIAWLTNNVAP 420
R+K+R+P + + ++G ++L + V+YF Y++ +Y N WL+ N
Sbjct: 378 RIKLRSPFILGACLTTSIGIAIVLGSQVHGVRYFGVYILCMGIYVNAACNCLWLSGNTGN 437
Query: 421 HYKRATALGLNQTLGNVSGAVAGQIYTTAP---YTFGHSFSLGCIVLSNLLAITQMFILK 477
++KRATALG+N G+ SG V+GQI+ Y G S SL V S + + Q+F+ K
Sbjct: 438 YFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQIFLYK 497
Query: 478 RINRKRQRIL 487
R N K++ I+
Sbjct: 498 RENDKKKAII 507
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 169 bits (429), Expect = 7e-42
Identities = 106/405 (26%), Positives = 187/405 (46%), Gaps = 5/405 (1%)
Query: 45 EQESLENENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQL 104
E E + E +D K E RK D R+LP+LA +Y ++LD+SN+ NA T+GM +DL
Sbjct: 34 EGEDVTTEVYILDHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGF 93
Query: 105 TSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLI 164
QY+ +S+FY ++ + F +LS+ ++LC A V+++ ++
Sbjct: 94 VGDQYNIMISIFYIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMM 153
Query: 165 ALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKP 224
A+R LG E P + ++ Y++ E +R G+ +K
Sbjct: 154 AVRWFLGMAESAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIK- 212
Query: 225 AGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGD 284
G L+GW++L++IEG ++ ++ +FL LP + +L+ E + K+R + +
Sbjct: 213 GGKLQGWQYLFLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAIS 272
Query: 285 GRFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPV 344
+ + K + + V L + ++ I+ +G++S M+V
Sbjct: 273 EKLSFKQSLTVFKHPIAILWLLEEMALGVPLNSINNWLPQIV-AAMGFSSVNTNLMTVAP 331
Query: 345 YILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSV---HNNSVKYFACYLITF 401
I AI L+ A+ISD LK R + + +G+I+ S+ ++ V YFAC+L+T
Sbjct: 332 AISGAIWLLVFAFISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTA 391
Query: 402 SLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIY 446
+ L W NN +RA + L NV G V+ I+
Sbjct: 392 GAAASSVLTSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIF 436
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 137 bits (345), Expect = 4e-32
Identities = 122/510 (23%), Positives = 228/510 (43%), Gaps = 31/510 (6%)
Query: 1 MQAQTTAMSSNSVDRYEMSKG------KSVIEVGEC----DGEGESGSIASFSIEQESLE 50
M + T+ +SS S K K+ EVGE D EG + ++A QE L
Sbjct: 1 MSSITSRVSSRSSHELTEKKSGVTNDFKNSFEVGEVKRLPDAEGTADAVA-----QELLA 55
Query: 51 NENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYS 110
+++ KE + K+D ++P++ Y + LD++ + A GM+ D + YS
Sbjct: 56 DDDFTYTAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMKTDTHIDGHTYS 115
Query: 111 NAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLL 170
+ ++FY+ YL A+ Y++ V WS + A ++ SL+ LR L
Sbjct: 116 SMTTLFYAGYLVAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAACRNGPSLLGLRFLA 175
Query: 171 GAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEG 230
G FE PA I ++ Y+++EQ R GL + G +
Sbjct: 176 GIFEASITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGLGHIH--GKVAS 233
Query: 231 WRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGRFEWS 290
WR+++I+ GL+S+ V +F+ +P + +LS+RE I R + + + +F+W
Sbjct: 234 WRYVFIVIGLMSLGWGV-VFVFIPSNPSKARFLSSREKRIALERVRDNRTGLENKQFKWK 292
Query: 291 YVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVYILAAI 350
+ ++A D I T+ +I G F T I+K GLGY + +++P+ +
Sbjct: 293 HAYEAFLD-PQVIMITLFTGVCMITNGIGVFSTLIIK-GLGYNELHSAVLNMPLGAIEVA 350
Query: 351 VFLISAYISDRLK-VRAPIFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFSLY--TGT 407
IS + K R I V N + G +++ + +++ Y + F+++ +
Sbjct: 351 AMFISGVLCKVFKNGRLLIGVFMNCLTLAGCLMIWKIPDSN-PYGRLVGVWFTMWVPASS 409
Query: 408 GLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIY---TTAPYTFGHSFSLG--CI 462
L ++ +++NVA + K+ +V V+ Q++ T Y G + CI
Sbjct: 410 ALLLSLISSNVAGYTKKTVTSATVFVFYSVGNIVSPQLFKSGQTPEYIEGIQAMIVSLCI 469
Query: 463 VLSNLLAITQMFILKRINRKRQRILSGEIS 492
+++ +T +I + N++R R+L+ + S
Sbjct: 470 IIAIAFVLTGYYIYE--NKRRDRLLAEDPS 497
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 127 bits (319), Expect = 4e-29
Identities = 121/513 (23%), Positives = 221/513 (42%), Gaps = 25/513 (4%)
Query: 8 MSSNSVDRY----EMSKGKSVIEVGECDGEGESGSIASFSIEQESLENENLEIDPKEEAA 63
MSS S+D E + K +++V D G A+F+ +L+ + EIDP+ E
Sbjct: 1 MSSISIDEKLKDPESVQNKEILDVDVGD-LSPKGVDAAFNY---ALDVDYDEIDPETERR 56
Query: 64 FVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYSTYLAA 123
VRK+D + P++ +Y + LD+++ A G++EDL++ + YS + + FY YL
Sbjct: 57 LVRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLVF 116
Query: 124 EXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFFPAMTL 183
E + ++ W + LC V +Y IALRVLLG E P L
Sbjct: 117 EFPASLLLQRFPLSKTLCVFLVIWGFL-LCMTSVANYPGFIALRVLLGMMESAASPGFIL 175
Query: 184 IISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEGLISV 243
+ + YK+ EQ R GLA + + + GW+ ++II G++++
Sbjct: 176 LTAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAK-RTSLPMRGWKLIFIICGVLAI 234
Query: 244 CASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGRFEWSYVFDALKDFKTYI 303
+ +P + +L+ + +++ R + +G+ F+ + + D +T+I
Sbjct: 235 FLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETMLDIRTWI 294
Query: 304 SFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVYI-----LAAIVFLISAYI 358
F ++ G TF + ++K +GY + + M +P L A FL S +I
Sbjct: 295 MFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFL-SLFI 353
Query: 359 SDRLKVRAPIFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFSLYTGTGLNIAWLTNNV 418
R+ V A I C +IG+ LLS A Y + + A +++N
Sbjct: 354 HKRM-VLATITTCIALIGS----CLLSFAGPPRAQLAGYYLLMVSPGAMIVMFAIISSNA 408
Query: 419 APHYKRATA---LGLNQTLGNVSGAVAGQIYTTAPYTFGHSFSLGCIVLSNLLAITQMFI 475
+ + K+ T + +GN+ G + Y + +GC + L+ ++
Sbjct: 409 SGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYA-ATLVTFPALYY 467
Query: 476 LKRINRKRQRILSGEISDDHRGVRNGDNALDFK 508
+ KR+ L+ E +HR ++ DF+
Sbjct: 468 VNWRENKRRDQLAAEGKIEHRPNAEFEDLTDFE 500
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 123 bits (308), Expect = 7e-28
Identities = 77/297 (25%), Positives = 136/297 (44%), Gaps = 3/297 (1%)
Query: 50 ENENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQY 109
E + +E+ P+E+ K+D + P++ +Y + +D+ + +A G+R DL++ QY
Sbjct: 63 EAKEIEVTPEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQY 122
Query: 110 SNAVSVFYSTYL---AAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIAL 166
S S FY YL F+V+ ++ L A Y S I L
Sbjct: 123 SWVTSAFYFGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVL 182
Query: 167 RVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAG 226
RVLLG E P T+I + +K +EQ R G+ + +
Sbjct: 183 RVLLGCAESVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSY 242
Query: 227 GLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGR 286
++GWR L++I G+I++ + +FL +P D +LS RE ++ R + G+
Sbjct: 243 AIKGWRTLFVITGVITIFIGILIFLWIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHE 302
Query: 287 FEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVP 343
+ + +ALKD +T++ F ++ G S+F++ +L GY+S+E M +P
Sbjct: 303 IKKYQIIEALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLP 359
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 118 bits (295), Expect = 2e-26
Identities = 113/484 (23%), Positives = 195/484 (39%), Gaps = 11/484 (2%)
Query: 34 GESGSIASFSIEQESLENENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNA 93
GE GS + + E + ID K D ++P+L + +D+S +
Sbjct: 15 GEKGSDSQEDVAVIFAEKHPI-IDKSLNRKLKLKTDLWVMPLLCLISAFQYMDKSTSNYS 73
Query: 94 YTSGMREDLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLC 153
G+R DL + QY+ + FY ++ S +++W I+
Sbjct: 74 SIMGIRTDLNMVGNQYNWVGTSFYLGFMVFSLPLSTLLQKFPLSKVTSAFIVAWGILMTL 133
Query: 154 NAFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXX 213
V SYAS IA R LLG E PA L I+ Y+K+EQ R
Sbjct: 134 TCLVHSYASYIATRTLLGILESVITPAFVLFIAQWYRKEEQFFRMAFLVAWNGLGGLIGG 193
Query: 214 XXXTGLASMKPAGGL--EGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEIL 271
GL + L WR L+II GLI++ V++F+ +P + +LS +E +++
Sbjct: 194 SMSYGLYKRELENNLTMSPWRILFIITGLITIINGVFIFIHIPDEPSKAWFLSEKEKDLV 253
Query: 272 KIRAKQRVAYMGDGRFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLG 331
R A +G +F+ + +A +D + Y+ F +Q + G S F + +LK LG
Sbjct: 254 LKRLDTDHAGLGSKKFKKYQILEACRDVRMYLYFFLQIAVAIPNGGLSNFSSIMLK-NLG 312
Query: 332 YTSREAQYMSVPVYILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVHNNSV 391
Y +A M++P ++ + I + R I + I L+
Sbjct: 313 YVKGKALLMNMPTSSISFAALTLFGLIPEFTNRRMDIALVGLAINLTSGSLIAFAKPTHA 372
Query: 392 KYFACYLITFSLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIY--TTA 449
+ +L S + ++ +++N A H K+ ++ V V Q + T A
Sbjct: 373 QLAGYWLFGISPIPYICI-LSCISSNSAGHTKKVFMSAVSMIGYCVGNMVGPQTFRSTQA 431
Query: 450 PYTFGHSFS-LGCIVLSNLLAITQMFILKRINRKR---QRILSGEISDDHRGVRNGDNAL 505
P G S + C ++ + I + R NR+R LS E+S++ +
Sbjct: 432 PKYQGAKVSFVVCYCVAIFIIIAIYAVNVRENRRRDEKNEYLSNELSEEDKKDLTDFENP 491
Query: 506 DFKY 509
+F+Y
Sbjct: 492 EFRY 495
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 105 bits (261), Expect = 2e-22
Identities = 109/467 (23%), Positives = 193/467 (40%), Gaps = 30/467 (6%)
Query: 44 IEQESLENENLEIDPKEEAAF----------VRKLDTRLLPMLAFMYFLSSLDRSNIGNA 93
+++ S NE+ ++ EEA F +RK+D +LP L Y L LD++ + A
Sbjct: 45 LDESSTANED-DVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYA 103
Query: 94 YTSGMREDLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLC 153
+ G+++ L+ ++SN ++F + Y+ E + + W I+ C
Sbjct: 104 ASMGIKDHLK--GNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLAC 161
Query: 154 NAFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXX 213
+A ++YASL+ +R LLG FE I + Y K EQ R
Sbjct: 162 HAACKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGG 221
Query: 214 XXXTGLASMKPAGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARE--TEIL 271
G W+ ++++ GL++V V FL LP + N +L+ E +
Sbjct: 222 LISFGFLHYH-GTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVE 280
Query: 272 KIRAKQRVAYMGDGRFEWSYVFDA-LKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGL 330
IRA Q + +F+ V + L D T+ + C + TF I
Sbjct: 281 HIRANQ--TGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGT-F 337
Query: 331 GYTSREAQYMSVPVYILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLS--VHN 388
G+ E + +P+ + A++ LI+ + R I + +G I+L+S + +
Sbjct: 338 GFDKYETALLQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLISLPLSH 397
Query: 389 NSVKYFACYLITFSLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIYT- 447
F+ YL+ T + I W + N + + KR + + NVS +A Q++
Sbjct: 398 KIGNLFSLYLLYSGSCVITNIYI-WNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRA 456
Query: 448 -TAPYTFGHSFSL---GCIVLSNLLAITQMFILKRINRKRQRILSGE 490
+AP +L C+ + L I +I K+ N KR + G+
Sbjct: 457 YSAPRYIPAKIALLVTQCVCVPLQLYIG--YICKKENEKRDKEQEGQ 501
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 102 bits (255), Expect = 1e-21
Identities = 92/371 (24%), Positives = 163/371 (43%), Gaps = 29/371 (7%)
Query: 59 KEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYS 118
K E + K+D +L YF++ LDRS+I NAY SGM+EDL++ + + VF
Sbjct: 19 KVEQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTC 78
Query: 119 TYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFF 178
Y+ + + S + + W ++T+ + V S +L+ LR + E F
Sbjct: 79 GYIIGQLPGSYALQRVPARLWFSVMNILWGLMTIFSFAVHSVRALMILRFFMAVAEASTF 138
Query: 179 PAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGL-ASMKPAGGLEGWRWLYII 237
I+ YK+ E KR T + +S+ GGL GWRWL+II
Sbjct: 139 AGTHYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLFII 198
Query: 238 EGLISVCASVW---LFLELPKDFDNIPYLSARETEI----LKIRAKQRVAYMGDGRFEWS 290
+G++++ S++ LF ++P + PY + +E E+ L R K++ +
Sbjct: 199 DGILTIPLSLYGLFLFPDVP-ETTKAPYFTEQEKELSFKRLPARPKKKPLTL-------K 250
Query: 291 YVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLG--LGYTSR--EAQYMSVPVYI 346
+ D ++ ++ Y C I G + + + +G + ++++ AQ + P I
Sbjct: 251 AIKDIVRSWRIY-----GLCILWIFSGETQAIAVNVLMGQWMKWSNKFSVAQINNYPTVI 305
Query: 347 LA--AIVFLISAYISDRL--KVRAPIFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFS 402
A + L ++ ISD+L R P + VI V +LL+ + F Y +
Sbjct: 306 TAVGVVSTLGASVISDKLAGNPRWPFGLFLCVITTVSATILLAWNVPDGAKFFAYFASGC 365
Query: 403 LYTGTGLNIAW 413
Y G + +W
Sbjct: 366 TYAGQAVWFSW 376
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 95.5 bits (236), Expect = 2e-19
Identities = 86/328 (26%), Positives = 138/328 (41%), Gaps = 13/328 (3%)
Query: 60 EEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYST 119
+E + KLD L Y++ LD NI NAY SGM+EDL + ++
Sbjct: 127 KEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVG 186
Query: 120 YLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFFP 179
+ + Y + L L WS++T+ A+V S L A+R +GAFE +
Sbjct: 187 NIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYL 246
Query: 180 AMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGL-ASMKPAGGLEGWRWLYIIE 238
A + YK E +R + + +S+ GLEGWRW +II+
Sbjct: 247 AYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFIID 306
Query: 239 GLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGRFEWSYVFD---- 294
++SV + F LP D N + + EI R + + G FE + VFD
Sbjct: 307 AIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFE-TKVFDIKLW 365
Query: 295 --ALKDFKTYI-SFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVYILAAIV 351
D+K YI + FC + ++ + L Y+ + +S+ L +
Sbjct: 366 KTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSL-KRYSIPKLNQLSMITPGLGMVY 424
Query: 352 FLISAYISDRLKVR--APIFV-CYNVIG 376
+++ I+D+L R A IF +N+IG
Sbjct: 425 LMLTGIIADKLHSRWFAIIFTQVFNIIG 452
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 93.2 bits (230), Expect = 8e-19
Identities = 100/448 (22%), Positives = 173/448 (38%), Gaps = 27/448 (6%)
Query: 60 EEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYST 119
EE VRK+D ++ + M+ L R NI A + DL++ + Y+ +V+
Sbjct: 69 EEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVI 128
Query: 120 YLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFFP 179
+LA+E + ++ WS+I + A +++ IA R LLG +GGF P
Sbjct: 129 FLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGGFIP 188
Query: 180 AMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEG 239
L +S Y E R +G+ M+ L GW++L+IIEG
Sbjct: 189 DNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEG 248
Query: 240 LISV---CASVWLFLELPKDFDNIPYLSAR------ETEILKIRAKQRVAYMGDGRFEWS 290
+S+ AS +L P + + E +I+ R + GD
Sbjct: 249 FLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSNRQP 308
Query: 291 YVFD----ALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVYI 346
F L +F + F + L ++++ ILK L Y++ + +++P
Sbjct: 309 VTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILK-SLNYSTFLSNILAIPGQA 367
Query: 347 LAAIVFLISAYISDRLKVRAPIFVCYNVIGA------VGYILLLSVHNNSVKYFACYLIT 400
L I ++A +S +LK ++ +C + V + L + N +KY I
Sbjct: 368 LLLINLPLAALLSRKLKEKS---LCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTGIL 424
Query: 401 FSLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAVAGQIYTTAP---YTFGHSF 457
YT + L W++ R L V +A +Y YT G+
Sbjct: 425 GLPYTHSIL-AGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKI 483
Query: 458 SLGCIVLSNLLAITQMFILKRINRKRQR 485
LG + +A+ F N+ + R
Sbjct: 484 LLGFTCFNICMAVATKFYYISRNKYKDR 511
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 85.9 bits (211), Expect = 1e-16
Identities = 88/410 (21%), Positives = 166/410 (40%), Gaps = 35/410 (8%)
Query: 67 KLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQL--TSKQYSN-----AVSVFYST 119
K+D R++P L +YFLS R + ++T + L T YS +++FY
Sbjct: 80 KMDLRIIPCLWILYFLSCCLRFTVSLSFTMNTAQGHSLIQTLSGYSAHYLALGLALFYVG 139
Query: 120 YLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSY----ASLIALRVLLGAFEG 175
Y+ E ++S + L+ ++ C+A + + S +ALR LG E
Sbjct: 140 YIIFEVPSNLMMAFIEPRIWVSRIQLTIGVVGACHAVLGTKHGNAQSYVALRFFLGVAES 199
Query: 176 GFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEGWRWLY 235
G +P + +S Y+ + GKR G M A GL G++W++
Sbjct: 200 GLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKMDGARGLYGYQWMF 259
Query: 236 IIEGLISVCASV----WL--------------FLELPKDFDNI-PYLSARETEILKIRAK 276
+I G++++ ++ WL F+ LPK + P T K
Sbjct: 260 LIWGVVAIAQALSIPWWLPAVASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADKSLHS 319
Query: 277 QRVAYMGDG-RFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAIL-KLGLGYTS 334
+ +A M G R++WS + + D + + + F + G + T I+ ++ ++
Sbjct: 320 RYIAEMNVGKRWQWSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLIIEEINPSFSG 379
Query: 335 REAQYMSVPVYILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVHNNSVKYF 394
+ ++ P+++ A+ + + DR + F +I G + +Y
Sbjct: 380 IDISLLNAPIWLADALGIVTVMPLYDRFHKKFSFFTGSCLIIIAGLAVANYAPRAWSRYG 439
Query: 395 ACYLITFSLYTGTGLNIAWLTNNVAPHYKR---ATALGLNQTLGNVSGAV 441
+I F L + +AW + ++A Y A++L L LGN+ V
Sbjct: 440 GLLMIGFGLGPTVPICMAWCSASMAKTYGDVGVASSLALVTGLGNLGSVV 489
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 84.3 bits (207), Expect = 4e-16
Identities = 92/419 (21%), Positives = 172/419 (40%), Gaps = 20/419 (4%)
Query: 35 ESGSIASFSIEQESLENENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAY 94
ES SI +E+ES+ ++ ++ + K+D +L + Y+++ +DR NAY
Sbjct: 4 ESKSITQHEVERESVSSKRAI----KKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAY 59
Query: 95 TSGMREDLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCN 154
SGM+EDL++ + + +VF Y+ ++SF +W ++TL
Sbjct: 60 ISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPRIWLSFCTFAWGLLTLGM 119
Query: 155 AFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXX 214
V S+ + A+R FE F ++ YK+ E R
Sbjct: 120 YKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGF 179
Query: 215 XXTGL-ASMKPAGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSA-------- 265
T + + GL GWRWL+II+ I++ +++ F+ P D +S
Sbjct: 180 MQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGLPDQTSAVSKFSMTRYIF 239
Query: 266 RETEILKIRAKQRVAYMGDGRFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAI 325
E E+ R ++ A R +WS + LK + ++ F++ + GF++ T
Sbjct: 240 NEQELHYAR-RRLPARDESTRLDWSTIPRVLKRWHWWM-FSLVWVLGGENLGFASNSTFA 297
Query: 326 LKL-GLGYTSREAQYMSVPVYILAAIVFLISA-YISDRLKVRA-PIFVCYNVIGAVGYIL 382
L L YT + ++ + + L SA Y+S + R + V +++ + +L
Sbjct: 298 LWLQNQKYTLAQRNNYPSGIFAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVL 357
Query: 383 LLSVHNNSVKYFACYLITFSLYTGTGLNIAWLTNNVAPHYKRATALGLNQTLGNVSGAV 441
+ + N F+ + Y G + +W N+ H + ++ SGAV
Sbjct: 358 IRADPLNPKVVFSAQYLGGVAYAGQAVFFSWA--NIICHADLQERAIVLASMNMFSGAV 414
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 82.4 bits (202), Expect = 1e-15
Identities = 104/491 (21%), Positives = 207/491 (41%), Gaps = 35/491 (7%)
Query: 22 KSVIEVGECDGEGESGSIA--SFSIEQESLENENLEIDPKEEAAFVRKLDTRLLPMLAFM 79
+ + +V + G+ + S+ +F+ Q++ + + L PK+E+ KL LL ML F+
Sbjct: 52 EDIADVEKAGGKKINNSLIDETFAFMQDAKKLDPLT--PKQESKLKWKLYIYLLLMLGFL 109
Query: 80 YFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYY 139
+ + ++ + + G+ +D+ +TS QY+N ++FY Y+ + +
Sbjct: 110 DMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGYIVGQFPGHYIMQTFPLGKF 169
Query: 140 MSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXX 199
+ + SWS+I + +Y LIALR LG E PAM + + + QEQ
Sbjct: 170 VGLVTFSWSVIVFLHCCAYNYGGLIALRFFLGFTESCLLPAMEATMGMFFTHQEQAFLQP 229
Query: 200 XXXXXXXXXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDN 259
GL + + + W+ II G I+ S++LF P +
Sbjct: 230 VFWISCLSCGIPAGFIAYGLEFVTKS--IAPWKLFMIITGGITFFLSIFLFFYYPDNPSK 287
Query: 260 IPYLSARET--EILKIRAKQRVAYMGDGRFEWSYVFDALKD----FKTYISFTIQFCQDV 313
+L+ E I ++R R + + F+ +ALKD T+ +FT+ +
Sbjct: 288 ARFLTDEEKLYTIDRVRKSTR-GGIENKIFKKHQFIEALKDPITWLFTFAAFTLMLSNN- 345
Query: 314 ILYGFSTFVTAILKLGLGYT---SREAQYMSVPVYILAAIVFLI---SAYISDRLKVRAP 367
+ Y + T++ L T A Y +V I ++LI SAY A
Sbjct: 346 LAYQQNLIFTSLNVSDLNSTLVGVALAGYNTVSAIIATFAMYLIPNQSAY-------HAM 398
Query: 368 IFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFSLYTGTGLNIAWLTNNVAPHYKRATA 427
++ ++ G + ++ L +N + A +I + + W T + K+ T
Sbjct: 399 FWMLPSITGGIAFVAL--PWSNRIGELATMIIASDFGITYIIALGWTTATSTGYTKKLTR 456
Query: 428 LGLNQTLG-NVSGAVAGQIYTTAPYTFGHSFSLGCIV----LSNLLAITQMFILKRINRK 482
GL +G ++ ++ Q++ + + + IV ++ ++ + IL R N++
Sbjct: 457 -GLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAWFVTPIIYLVARVILARRNKQ 515
Query: 483 RQRILSGEISD 493
R+ + +I++
Sbjct: 516 RKELKDKKIAE 526
>SPAC1B3.15c [G] KOG2533 Permease of the major facilitator superfamily
Length = 628
Score = 75.5 bits (184), Expect = 2e-13
Identities = 108/507 (21%), Positives = 193/507 (37%), Gaps = 45/507 (8%)
Query: 22 KSVIEVGECDGEGESGSIASFSIEQESLENENLEIDPKEEAAFVR-KLDTRLLPMLAFMY 80
KS+++ D E + S ES++ + K+ + +R KLD R++ L Y
Sbjct: 106 KSMLDEKHPDSEDITAVSLSTPPFPESIDVARFSSEEKKILSRIRRKLDLRIITCLWITY 165
Query: 81 FLSSLDRSNIGNAYTSGMRED---LQLTSKQYSNAVSV----FYSTYLAAEXXXXXXXXX 133
FLS +I + T + LQ S + +SV Y + + +
Sbjct: 166 FLSRSVTYSISLSLTMNKHQGHSLLQTVSGLNYHTLSVGTGLSYVSLIIFDLPSNLLMTR 225
Query: 134 XXXXYYMSFLVLSWSIITLCNAFV----QSYASLIALRVLLGAFEGGFFPAMTLIISILY 189
++S + ++ II C+A + S + IALR G G +P S Y
Sbjct: 226 ADPRLWLSRIQVTTGIIGACHAVLGTKGSSASGFIALRFFNGLAIAGMWPGFAFYTSRFY 285
Query: 190 KKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEGLISVCASVWL 249
+ Q GKR M GL G++W+++I G+++ ++L
Sbjct: 286 RDQHLGKRIGWYYTAAQISSVATSLLSAAFQKMDGLHGLYGYQWMFLIWGVVAFTQGLFL 345
Query: 250 FLELPKDFDN---------------IPYLSARE-TEILKIRAKQRVAYMGDGRFEWSYVF 293
LP N + +L A E T + + YM + + S+
Sbjct: 346 PRWLPCIKHNQHNEKWISWIRIPKFLGFLKASENTGLTPEEEEVHAIYMAEMQVGKSWTL 405
Query: 294 ----DALKDFKTYISFTIQFCQDVILYGFSTFVTAIL-KLGLGYTSREAQYMSVPVYILA 348
DA D + + + F I G + + I+ ++ ++S + P+++
Sbjct: 406 TDLADAFLDVRLWPPIFMFFGVVGISNGLVNYSSLIISEINENFSSVTVSLLVAPIWVFD 465
Query: 349 AIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVHNNSVKYFACYLITFSLYTGTG 408
AI L + DR + FV + G ++ V N +Y ++ F L
Sbjct: 466 AIAILTVLPLHDRFHKKMLFFVGSCLFVLAGLLITTFVSNVWGRYVGLLILGFGLGPTVP 525
Query: 409 LNIAWLTNNVAPHYKR---ATALGLNQTLGNVSGAVA-GQIYT--TAPYTFGHSFSLGC- 461
+ + W+++ + P + A L + LGN+ VA +Y+ A TF S C
Sbjct: 526 IIMTWVSSAMGPSHGDVGVAAGLAIVSGLGNLGSVVATSALYSGWKADTTFRRSNETMCG 585
Query: 462 -----IVLSNLLAITQMFILKRINRKR 483
IV S ++ + Q F ++R KR
Sbjct: 586 MVGIAIVASIVMHMVQKFNIRRFPFKR 612
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 69.7 bits (169), Expect = 1e-11
Identities = 80/394 (20%), Positives = 155/394 (39%), Gaps = 19/394 (4%)
Query: 41 SFSIEQESLENENLEIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMRE 100
+FS QE+ + E L PK++ KL +L ML + + +D++ + + G+ E
Sbjct: 60 TFSFMQEAKDLEPLT--PKQDKRLRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFE 117
Query: 101 DLQLTSKQYSNAVSVFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSY 160
D + S QY++ ++FY ++ + +++ W+II + ++
Sbjct: 118 DTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFPVSKFVAASTALWTIIIFLHCAAYNF 177
Query: 161 ASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLA 220
+ L+ALR LG E P M I + + EQ G+
Sbjct: 178 SGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNIPAGFIAYGVQ 237
Query: 221 SMKPAGGLEGWRWLYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVA 280
K + W+ II G I+ ++ LF P + +L+ +E + + +R
Sbjct: 238 YAK--NTISPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKE-RLYTVDRVRRSN 294
Query: 281 YMG--DGRFEWSYVFDALKDFKTYISFTIQFCQDV---ILYGFSTFVTAILKLGLGYT-- 333
+ G F+ V +ALKD T++ FC + + Y + T++ L T
Sbjct: 295 HSGIESKTFKKYQVIEALKDPVTWLFTFHVFCNQLSNNLAYQQNLLFTSLNVSDLNSTLV 354
Query: 334 -SREAQYMSVPVYILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVHNNSVK 392
A Y V A I + + I ++ I+ ++ G + + + H +
Sbjct: 355 GVASAGYNCVS----AIIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVAMSWDH--KIG 408
Query: 393 YFACYLITFSLYTGTGLNIAWLTNNVAPHYKRAT 426
A +I + +++ W T + A + K+ T
Sbjct: 409 ELAAIIIASNFGIPFIISLGWTTASCAGYTKKLT 442
>YGR065c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 66.6 bits (161), Expect = 8e-11
Identities = 77/359 (21%), Positives = 131/359 (36%), Gaps = 17/359 (4%)
Query: 59 KEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVSVFYS 118
K E + KLD + + + S+D +N NAY S M+EDL + Y ++
Sbjct: 116 KAERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANV 175
Query: 119 TYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFF 178
+ + + + L W+ T S A L A R +L AF ++
Sbjct: 176 GAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYY 235
Query: 179 PAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGL-ASMKPAGGLEGWRWLYII 237
P I+ Y E R + + S+ GL GWRW+++I
Sbjct: 236 PVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFLI 295
Query: 238 EGL-ISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDG----------- 285
+ + IS+ ++ F +P L + EI RA+ + + DG
Sbjct: 296 DAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWS 355
Query: 286 RFEWSYVFDALKDFKTYISFTIQFCQDVILYGFSTFVTAILKLGLGYTSREAQYMSVPVY 345
R W VF F + F C + +S T LK Y+ + +SV
Sbjct: 356 RKLWKKVF-CTPAFWVLVVF--DTCSWNNMTAYSGSYTLWLKSNTKYSIAQVNNLSVIPA 412
Query: 346 ILAAIVFLISAYISDRLKVRAPIFVCYNVIGAVGYILLLSVH-NNSVKYFACYLITFSL 403
L + A+ +D + + V ++ V LL+ + K++A + FS+
Sbjct: 413 CLGFAYVIFCAFGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTYFSV 471
>YOL163w [G] KOG2533 Permease of the major facilitator superfamily
Length = 169
Score = 57.4 bits (137), Expect = 5e-08
Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 7/135 (5%)
Query: 144 VLSWSIITLCNAFVQSYASLIALRVLLGAFEGGFFPAMTLIISILYKKQEQGKRXXXXXX 203
+++WS++ + +S R L+G FEGGF + L +S Y E R
Sbjct: 1 MIAWSLVATLQCKMTGKSSFYTCRALMGLFEGGFVADLVLWMSYFYSSSELSIRLSFFWV 60
Query: 204 XXXXXXXXXXXXXTGLASMKPAGGLEGWRWLYIIEGLISVCASV-WLFLELP------KD 256
G+ M+ GG+ GW+WL++IE + ++ + FL +P K
Sbjct: 61 TLSLTQIITSIVAFGVFHMRGIGGMAGWQWLFLIERIFTLVIGISAYFLMVPSVVQTKKP 120
Query: 257 FDNIPYLSARETEIL 271
+ + + RE +I+
Sbjct: 121 WSKKGWFTEREEKII 135
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 54.3 bits (129), Expect = 4e-07
Identities = 47/251 (18%), Positives = 102/251 (39%), Gaps = 4/251 (1%)
Query: 55 EIDPKEEAAFVRKLDTRLLPMLAFMYFLSSLDRSNIGNAYTSGMREDLQLTSKQYSNAVS 114
EI P++E RKL + ++ + L +D++ + G ED LT Y+ +
Sbjct: 42 EITPEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNT 101
Query: 115 VFYSTYLAAEXXXXXXXXXXXXXYYMSFLVLSWSIITLCNAFVQSYASLIALRVLLGAFE 174
+FY + + ++ L+ +W+I+ + +++ ++ALR LG E
Sbjct: 102 LFYVGFAIGQFPGQYLAQKLPLGKFLGGLLATWTILIFLSCTAYNFSGVVALRFFLGLTE 161
Query: 175 GGFFPAMTLIISILYKKQEQGKRXXXXXXXXXXXXXXXXXXXTGLASM-KPAGGLEGWRW 233
P + + + + E+ G+ + P+ L W+
Sbjct: 162 SVVIPILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGVLHITNPSISL--WKI 219
Query: 234 LYIIEGLISVCASVWLFLELPKDFDNIPYLSARETEILKIRAKQRVAYMGDGR-FEWSYV 292
II G ++ +V + L P + ++ + S +E + R + + + F+ S
Sbjct: 220 FTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKKSQF 279
Query: 293 FDALKDFKTYI 303
+A+KD+ T++
Sbjct: 280 REAMKDYITWL 290
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.323 0.138 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,254,276
Number of Sequences: 60738
Number of extensions: 1008548
Number of successful extensions: 2560
Number of sequences better than 1.0e-05: 21
Number of HSP's better than 0.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2505
Number of HSP's gapped (non-prelim): 22
length of query: 511
length of database: 30,389,216
effective HSP length: 111
effective length of query: 400
effective length of database: 23,647,298
effective search space: 9458919200
effective search space used: 9458919200
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)