ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4853 good R KOG0254 General function prediction only Predicted transporter (major facilitator superfamily)
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4853 1719774 1717906 -623
(623 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YHL047c [R] KOG0254 Predicted transporter (major facilitator sup... 717 0.0
YHL040c [R] KOG0254 Predicted transporter (major facilitator sup... 691 0.0
YCL073c [R] KOG0254 Predicted transporter (major facilitator sup... 508 e-143
YKR106w [R] KOG0254 Predicted transporter (major facilitator sup... 505 e-143
YEL065w [R] KOG0254 Predicted transporter (major facilitator sup... 448 e-125
YOL158c [R] KOG0254 Predicted transporter (major facilitator sup... 260 5e-69
SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator ... 204 4e-52
SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator... 139 2e-32
SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator ... 130 8e-30
YPR198w [R] KOG0254 Predicted transporter (major facilitator sup... 58 5e-08
YGR224w [R] KOG0254 Predicted transporter (major facilitator sup... 53 1e-06
SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitato... 51 5e-06
>YHL047c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 637
Score = 717 bits (1851), Expect = 0.0
Identities = 350/601 (58%), Positives = 430/601 (71%), Gaps = 2/601 (0%)
Query: 21 NEFDLDEKQQPEVLNEYGLPDKLRFTRSLVLRKTEILAQQYDTWYWKAVLLFSVFLCSYG 80
NE +DEK + + DKL+ T+SL++RK+E++A++YDTW KA+ LFS F+C++
Sbjct: 23 NELMVDEKMDDDSSPRDEMKDKLKGTKSLIIRKSELMAKKYDTWQLKAIFLFSAFICTFA 82
Query: 81 YGLDGSVRSVYTTYATNXXXXXXXXXXXXXXXXVIGASAQVFFARLSDVFGRLTLLIVAT 140
YGLD S+R Y TYA N +I A +QV F LSD+FGRLTL +V+
Sbjct: 83 YGLDSSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFGGLSDIFGRLTLFLVSI 142
Query: 141 VFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXXXXXXXXXSDFSSLRWRLFYTFVPSWP 200
V Y VGTIIQSQAYDVQRYAAGAVFY SD SSL+WRLFYT +PSWP
Sbjct: 143 VLYIVGTIIQSQAYDVQRYAAGAVFYYVGLVGVMLQVVLMLSDNSSLKWRLFYTLIPSWP 202
Query: 201 FIINMWVSGNVVNAANPLENWSWSIGMWAFIFPLTCLPLVCCILHMRYRASKTEAWRHLQ 260
II WVSG+VV AANPLENWSW+I MWAFIFPL C+PL+ C+LHMR++ W+ LQ
Sbjct: 203 SIITTWVSGSVVEAANPLENWSWNIAMWAFIFPLCCIPLILCMLHMRWKVRNDVEWKELQ 262
Query: 261 LEKTYYQSHGLLQTLIQLFWKLDXXXXXXXXXXXXCILVPLTLAGGVSQKWNNPHVIAPF 320
EK+YYQ+HGL+Q L+QLFWKLD CILVPLTLAGGVS W N +I PF
Sbjct: 263 DEKSYYQTHGLVQMLVQLFWKLDVVGVLLFTAGVGCILVPLTLAGGVSTNWRNSKIIGPF 322
Query: 321 VLGFVLLPIFVVWESKWALDPIAPFELLKDRGVWSALTIQFLIYFVYQMAVGYLYTILVI 380
VLGFVL+P F+ WES+ AL P APF+LLKDRGVW+ L I F I FVYQMA GYLYTILV+
Sbjct: 323 VLGFVLVPGFIYWESRLALVPFAPFKLLKDRGVWAPLGIMFFICFVYQMAAGYLYTILVV 382
Query: 381 AVDESTTSATRITSVYSFTAAVASPFFALVVTRSKRLKPYIITGCSLWMVAMGILYHFRS 440
AVDES +SATRI ++YSF AV +PF L+VTRS RLK YII G SL+ + MG+ Y +RS
Sbjct: 383 AVDESASSATRIINLYSFVTAVVAPFLGLIVTRSSRLKSYIIFGGSLYFITMGLFYRYRS 442
Query: 441 GKDSDKGIIGGLVLWGLTSTLFTYPVTVSLQSITSHENMASVTALNYTIYRIXXXXXXXX 500
G+D+D GII G+V+WGL+S LF YP VS+QS+TSHENMA+VTALNYT++RI
Sbjct: 443 GQDADGGIIAGMVIWGLSSCLFDYPTIVSIQSVTSHENMATVTALNYTVFRIGGAVAAAI 502
Query: 501 XXXIWTQLLYKKLLKEMNGDATLATAAYGSPFDFILDYPWGTPMRDAMVESYRYVQKYEV 560
IWTQ LY KLL M GDA LATAAYGSP FIL PWGTP+R AMVE+YR+VQKYEV
Sbjct: 503 SGAIWTQSLYPKLLHYM-GDADLATAAYGSPLTFILSNPWGTPVRSAMVEAYRHVQKYEV 561
Query: 561 LVALIFTVPMFILSMFLRDPPLTDDQAQENLKEGEYINTEHDDPILAWMDDKWTRITGGK 620
+VAL+F+ PMF+L+ +RDP LT+D AQ+ L + EY+ T+ DDPI W+ ++ + GG
Sbjct: 562 IVALVFSAPMFLLTFCVRDPRLTEDFAQK-LPDREYVQTKEDDPINDWIAKRFAKALGGH 620
Query: 621 K 621
K
Sbjct: 621 K 621
>YHL040c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 627
Score = 691 bits (1782), Expect = 0.0
Identities = 328/604 (54%), Positives = 425/604 (70%), Gaps = 12/604 (1%)
Query: 25 LDEKQQPEVLNE-----YGLP------DKLRFTRSLVLRKTEILAQQYDTWYWKAVLLFS 73
++ + PE N+ YGLP + LR RSL++++TEI+ Y+ WY +A+LL S
Sbjct: 21 MEHELNPETHNDSNSDSYGLPQLSEKYNALRQNRSLIIQQTEIIGSAYNKWYLQAILLLS 80
Query: 74 VFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXXXXXVIGASAQVFFARLSDVFGRL 133
F+C YGYGLDG++R +YT YAT+ V+ A++Q+ +ARLSDVFGRL
Sbjct: 81 AFICGYGYGLDGNIRYIYTGYATSSYSEHSLLSTINVINAVVSAASQIIYARLSDVFGRL 140
Query: 134 TLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXXXXXXXXXSDFSSLRWRLFY 193
L I A + Y VGTIIQSQAYDVQRYAAGA+FYN SDFSSL+WRL Y
Sbjct: 141 YLFISAVILYVVGTIIQSQAYDVQRYAAGAIFYNAGYVGVILILLIILSDFSSLKWRLLY 200
Query: 194 TFVPSWPFIINMWVSGNVVNAANPLENWSWSIGMWAFIFPLTCLPLVCCILHMRYRASKT 253
FVP+WPFIIN W++GN+ + ANP+ NWSW +GMWAFIFPL+C+P+V C+LHM++RA KT
Sbjct: 201 QFVPTWPFIINTWIAGNITSRANPVVNWSWDVGMWAFIFPLSCVPIVLCMLHMQWRARKT 260
Query: 254 EAWRHLQLEKTYYQSHGLLQTLIQLFWKLDXXXXXXXXXXXXCILVPLTLAGGVSQKWNN 313
W L+ +K+YYQ HG ++ L QLFW LD CILVPLTLAGGV WN+
Sbjct: 261 PEWHALKGQKSYYQEHGFIKILKQLFWMLDVVGVLLMGCSLGCILVPLTLAGGVKTTWND 320
Query: 314 PHVIAPFVLGFVLLPIFVVWESKWALDPIAPFELLKDRGVWSALTIQFLIYFVYQMAVGY 373
+I PFVLGFVL+PI +WE ++A DPI P+ L+KDR VWS++ I FLI F+Y MA Y
Sbjct: 321 SRLIGPFVLGFVLIPILWIWEYRFARDPILPYRLVKDRAVWSSMGISFLIDFIYYMAADY 380
Query: 374 LYTILVIAVDESTTSATRITSVYSFTAAVASPFFALVVTRSKRLKPYIITGCSLWMVAMG 433
LYT++++AV+ES SATRI ++ SF + VASPFFAL+VTR RLKP+I+ GC+LWMVAMG
Sbjct: 381 LYTVMIVAVNESVKSATRIATLSSFVSTVASPFFALLVTRCTRLKPFIMFGCALWMVAMG 440
Query: 434 ILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSLQSITSHENMASVTALNYTIYRIX 493
+LYHFR G S GIIG L +WG+ +TLFTYPVTVS+QS SHENMA+VTALNYT+YRI
Sbjct: 441 LLYHFRGGSQSHSGIIGALCVWGVGTTLFTYPVTVSVQSAVSHENMATVTALNYTLYRIG 500
Query: 494 XXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYGSPFDFILDYPWGTPMRDAMVESYR 553
IWTQ LYK++LK M GD LAT AY SP+ FI Y WGTP R+A++ +Y+
Sbjct: 501 SAVGSAVSGAIWTQTLYKQILKRM-GDVALATTAYESPYTFIETYTWGTPQRNALMNAYK 559
Query: 554 YVQKYEVLVALIFTVPMFILSMFLRDPPLTDDQAQENLKEGEYINTEHDDPILAWMDDKW 613
YVQ+ E +VAL+F VP+ S+ LRDP LTD A E +++GEY++T+ +DPIL W +
Sbjct: 560 YVQRLETIVALVFCVPLIAFSLCLRDPKLTDTVAVEYIEDGEYVDTKDNDPILDWFEKLP 619
Query: 614 TRIT 617
++ T
Sbjct: 620 SKFT 623
>YCL073c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 508 bits (1307), Expect = e-143
Identities = 247/572 (43%), Positives = 355/572 (61%), Gaps = 1/572 (0%)
Query: 51 LRKTEILAQQYDTWYWKAVLLFSVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXX 110
L++ EI++ Q+D+ +K +L+ + F+C +G LD ++RS YT YATN
Sbjct: 43 LKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV 102
Query: 111 XXXVIGASAQVFFARLSDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXX 170
V+ +QV ++RLSD FGRL L +VAT+FY +GTIIQSQA + YAAG+VFYN
Sbjct: 103 INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGY 162
Query: 171 XXXXXXXXXXXSDFSSLRWRLFYTFVPSWPFIINMWVSGNVVNAANPLENWSWSIGMWAF 230
SDFSSL+WR+FY + WP+II W+SGN++ AANP +NWSW+I MWAF
Sbjct: 163 VGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF 222
Query: 231 IFPLTCLPLVCCILHMRYRASKTEAWRHLQLEKTYYQSHGLLQTLIQLFWKLDXXXXXXX 290
I+PL+ LP++ IL+M+Y++SKT WR L+ + ++ GL + L+ LFWKLD
Sbjct: 223 IYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLI 282
Query: 291 XXXXXCILVPLTLAGGVSQKWNNPHVIAPFVLGFVLLPIFVVWESKWALDPIAPFELLKD 350
CILVPLTLA SQKW+N +IA V G L IF+ WE+K+A P+ PF+LL D
Sbjct: 283 TVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSD 342
Query: 351 RGVWSALTIQFLIYFVYQMAVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALV 410
RG+W+ L + F +F + ++ YLY +L++++ ES+TSA RI ++ F AA ASPF++L+
Sbjct: 343 RGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLL 402
Query: 411 VTRSKRLKPYIITGCSLWMVAMGILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSL 470
V ++++LK +I GC+ WMV MG+ Y +R G S +G+I V+ GL+ L + V V L
Sbjct: 403 VAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVIL 462
Query: 471 QSITSHENMASVTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYGS 530
Q++T+H MA +T + YT ++ IWTQ + +L K + D TLA AY S
Sbjct: 463 QAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGND-TLAEIAYAS 521
Query: 531 PFDFILDYPWGTPMRDAMVESYRYVQKYEVLVALIFTVPMFILSMFLRDPPLTDDQAQEN 590
P+ FI DYPWG+P RDA+VESYRYVQ+ + V L TVP F +MF+RDP L D E
Sbjct: 522 PYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFAFTMFMRDPELIDKATHEE 581
Query: 591 LKEGEYINTEHDDPILAWMDDKWTRITGGKKV 622
E + ++ I + + + KK+
Sbjct: 582 FTEDGLVVLPDEENIFSQIKALFRHNRSNKKL 613
>YKR106w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 615
Score = 505 bits (1300), Expect = e-143
Identities = 243/543 (44%), Positives = 345/543 (62%), Gaps = 1/543 (0%)
Query: 51 LRKTEILAQQYDTWYWKAVLLFSVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXX 110
L++ EI++ Q+D+ +K +L+ + F+C +G LD ++RS YT YATN
Sbjct: 43 LKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV 102
Query: 111 XXXVIGASAQVFFARLSDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXX 170
V+ +QV ++RLSD FGRL L +VAT+FY +GTIIQSQA + YAAG+VFYN
Sbjct: 103 INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGY 162
Query: 171 XXXXXXXXXXXSDFSSLRWRLFYTFVPSWPFIINMWVSGNVVNAANPLENWSWSIGMWAF 230
SDFSSL+WR+FY + WP+II W+SGN++ AANP +NWSW+I MWAF
Sbjct: 163 VGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAF 222
Query: 231 IFPLTCLPLVCCILHMRYRASKTEAWRHLQLEKTYYQSHGLLQTLIQLFWKLDXXXXXXX 290
I+PL+ LP++ IL+M+Y++SKT WR L+ + ++ GL + L+ LFWKLD
Sbjct: 223 IYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLI 282
Query: 291 XXXXXCILVPLTLAGGVSQKWNNPHVIAPFVLGFVLLPIFVVWESKWALDPIAPFELLKD 350
CILVPLTLA SQKW+N +IA V G L IF+ WE+K+A P+ PF+LL D
Sbjct: 283 TVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSD 342
Query: 351 RGVWSALTIQFLIYFVYQMAVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALV 410
RG+W+ L + F +F + ++ YLY +L++++ ES+TSA RI ++ F AA ASPF++L+
Sbjct: 343 RGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLL 402
Query: 411 VTRSKRLKPYIITGCSLWMVAMGILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSL 470
V ++++LK +I GC+ WMV MG+ Y +R G S +G+I V+ GL+ L + V V L
Sbjct: 403 VAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVIL 462
Query: 471 QSITSHENMASVTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYGS 530
Q++T+H MA +T + YT ++ IWTQ + +L K + D TLA AY S
Sbjct: 463 QAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGND-TLAEIAYAS 521
Query: 531 PFDFILDYPWGTPMRDAMVESYRYVQKYEVLVALIFTVPMFILSMFLRDPPLTDDQAQEN 590
P+ FI DYPWG+P RDA+VESYRYVQ+ + V L TVP F +MF+R+P L D E
Sbjct: 522 PYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTMFMRNPELIDKATHEE 581
Query: 591 LKE 593
E
Sbjct: 582 FTE 584
>YEL065w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 628
Score = 448 bits (1152), Expect = e-125
Identities = 235/548 (42%), Positives = 322/548 (57%), Gaps = 7/548 (1%)
Query: 55 EILAQQYDTWYWKAVLLFSVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXXXXXV 114
EI A+ Y+ ++ L FS+FL +Y YGLDG++R + YAT+ V
Sbjct: 58 EIYAEMYNRPIYRVALFFSLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNCIKTV 117
Query: 115 IGASAQVFFARLSDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXX 174
I A Q+FFARLSD+FGR +++IV+ +FYS+GTII+SQA ++ R+A G FY
Sbjct: 118 IAAVGQIFFARLSDIFGRFSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGLTGII 177
Query: 175 XXXXXXXSDFSSLRWRLFYTFVPSWPFIINMWVSGNVVNAANPLENWSWSIGMWAFIFPL 234
SDFS+L WRL F+P+ PFIIN W+SGNV +A + NW W IGMWAFI PL
Sbjct: 178 LILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAID--ANWKWGIGMWAFILPL 235
Query: 235 TCLPLVCCILHMRYRASKTEAWRHLQLEKTYYQSHGLLQTLIQL-FWKLDXXXXXXXXXX 293
C+PL C+LHMRY A K A L+ E I + FWKLD
Sbjct: 236 ACIPLGICMLHMRYLARK-HAKDRLKPEFEALNKLKWKSFCIDIAFWKLDIIGMLLITVF 294
Query: 294 XXCILVPLTLAGGVSQKWNNPHVIAPFVLGF-VLLPIFVVWESKWALDPIAPFELLKDRG 352
C+LVP TLAGG+ ++W H+I P V+G+ V+LP++++WE K++ P+ P++L++DRG
Sbjct: 295 FGCVLVPFTLAGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLIQDRG 354
Query: 353 VWSALTIQFLIYFVYQMAVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALVVT 412
++ AL I F I F + M Y+YT+LV+AV ES SATRITS+YSF + + ++
Sbjct: 355 IFFALLIAFFINFNWYMQGDYMYTVLVVAVHESIKSATRITSLYSFVSVIVGTILGFILI 414
Query: 413 RSKRLKPYIITGCSLWMVAMGILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSLQ- 471
+ +R KP+II G S W+V+ G+L H+R + GIIG L L G + FTY S+Q
Sbjct: 415 KVRRTKPFIIFGISCWIVSFGLLVHYRGDSGAHSGIIGSLCLLGFGAGSFTYVTQASIQA 474
Query: 472 SITSHENMASVTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYGSP 531
S +H MA VT+L Y I +WT +L K++ K ++ D TLA AYGSP
Sbjct: 475 SAKTHARMAVVTSLYLATYNIGSAFGSSVSGAVWTNILPKEISKRIS-DPTLAAQAYGSP 533
Query: 532 FDFILDYPWGTPMRDAMVESYRYVQKYEVLVALIFTVPMFILSMFLRDPPLTDDQAQENL 591
F FI Y WGTP R A+V SYRYVQK ++ L+F P+ + LR+ LTD A E
Sbjct: 534 FTFITTYTWGTPERIALVMSYRYVQKILCIIGLVFCFPLLGCAFMLRNHKLTDSIALEGN 593
Query: 592 KEGEYINT 599
E NT
Sbjct: 594 DHLESKNT 601
>YOL158c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 606
Score = 260 bits (664), Expect = 5e-69
Identities = 166/537 (30%), Positives = 262/537 (47%), Gaps = 19/537 (3%)
Query: 67 KAVLLFSVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXXXXXVIGASAQVFFARL 126
K LL ++FL Y GL G + TYA N ++ + V +AR+
Sbjct: 63 KTALLVALFLQGYCTGLGGQISQSIQTYAANSFGKHSQVGSINTVKSIVASVVAVPYARI 122
Query: 127 SDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXXXXXXXXXSDFSS 186
SD FGR+ I A V Y++G II + AG V D S
Sbjct: 123 SDRFGRIECWIFALVLYTIGEIISAATPTFSGLFAGIVIQQFGYSGFRLLATALTGDLSG 182
Query: 187 LRWRLFYTFVPSWPFIINMWVSGNVVN--AANPLE-NWSWSIGMWAFIFPLTCLPLVCCI 243
LR R F + P IIN WVSGN+V+ A N W W G++ I P++ L LV
Sbjct: 183 LRDRTFAMNIFLIPVIINTWVSGNIVSSVAGNVAPYKWRWGYGIFCIIVPISTLILVLPY 242
Query: 244 LHMRYRASKTEAWRHLQLEKTYYQSHGLLQTLIQLFWK----LDXXXXXXXXXXXXCILV 299
++ +Y + WR +L + G QTL Q WK ++ +L+
Sbjct: 243 VYAQYIS-----WRSGKLPPLKLKEKG--QTLRQTLWKFADDINLIGVILFTAFLVLVLL 295
Query: 300 PLTLAGGVSQKWNNPHVIAPFVLGFVLLPIFVVWESKWALDPIAPFELLKDRGVWSALTI 359
PLT+AGG + KW H+IA V+G L IF++WE K+A +P P L D ++ AL +
Sbjct: 296 PLTIAGGATSKWREGHIIAMIVVGGCLGFIFLIWELKFAKNPFIPRVYLGDPTIYVALLM 355
Query: 360 QFLIYFVYQMAVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALVVTRSKRLKP 419
+F+ Q+ + YL T+L++A EST SA RI +Y+F + + +++ K
Sbjct: 356 EFVWRLGLQIELEYLVTVLMVAFGESTLSAQRIAQLYNFLQSCTNIVVGIMLHFYPHPKV 415
Query: 420 YIITGCSLWMVAMGILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSLQSITSHENM 479
+++ G L ++ MG+LY +R D G+IG ++ G+ + +P+ + + T+H M
Sbjct: 416 FVVAGSLLGVIGMGLLYKYRVVYDGISGLIGAEIVVGIAGGMIRFPMWTLVHASTTHNEM 475
Query: 480 ASVTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYGSPFDFILDYP 539
A+VT L ++Y+I IWTQ L K+L++ + ++L A Y SP +++ YP
Sbjct: 476 ATVTGLLMSVYQIGDAVGASIAGAIWTQRLAKELIQRLG--SSLGMAIYKSPLNYLKKYP 533
Query: 540 WGTPMRDAMVESYRYVQKYEVLVALIFTVPMFILSMFLRDPPLTDDQ---AQENLKE 593
G+ +R M+ESY +Q+ ++V++ F +L FLR + Q A+E KE
Sbjct: 534 IGSEVRVQMIESYSKIQRLLIIVSISFAAFNAVLCFFLRGFTVNKKQSLSAEEREKE 590
>SPBC4F6.09 [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 612
Score = 204 bits (518), Expect = 4e-52
Identities = 134/515 (26%), Positives = 224/515 (43%), Gaps = 11/515 (2%)
Query: 69 VLLFSVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXXXXXVIGASAQVFFARLSD 128
+ FS+FL + T YAT+ +I A+ + ARLSD
Sbjct: 95 ICYFSIFLLFFAISFQAECYYSLTAYATSAFAGHSLLSTIAVANNIISAAIKPPLARLSD 154
Query: 129 VFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXXXXXXXXXSDFSSLR 188
VFGRL + + + Y VG I+ + + +VQ YA G+V YN +D SS+
Sbjct: 155 VFGRLEAFLFSLLLYLVGLILMAASTNVQTYAGGSVLYNAGYTGVELIMTIFMADTSSMA 214
Query: 189 WRLFYTFVPSWPFIINMWVSGNVVNAANPLENWSWSIGMWAFIFPLTCLPLVCCILHMRY 248
R + PF++ +W+ V W W I +W + P +P + + ++
Sbjct: 215 NRSLVLGISYLPFVVTIWIGPRVAQEFYMHSTWRWGIAVWTILIPACSIPFLAVYSYYQF 274
Query: 249 RASKTEAWRHLQLEKTYYQSHGLLQTLIQLFWKLDXXXXXXXXXXXXCILVPLTLAGGVS 308
R AWR L+ T L ++LF KLD +L+ ++LA +
Sbjct: 275 R-----AWREGALKGT------LTINPVELFKKLDIIGLILMTAGLALVLLSISLASYDT 323
Query: 309 QKWNNPHVIAPFVLGFVLLPIFVVWESKWALDPIAPFELLKDRGVWSALTIQFLIYFVYQ 368
KW++ I ++G + L FV++E A P PF L+++ + + + FL Y +
Sbjct: 324 GKWSDAKFIVMIIIGGLCLIAFVLYEIFVASFPALPFRLMREPTIGACCAMSFLFYITFY 383
Query: 369 MAVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALVVTRSKRLKPYIITGCSLW 428
Y Y+ L + S T+A I+ YSFT+ F +++ +KR K Y + ++
Sbjct: 384 CWDNYYYSFLQVVHYTSITAAGYISYTYSFTSCATGFFLGILIRLTKRYKWYFVASIPVY 443
Query: 429 MVAMGILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSLQSITSHENMASVTALNYT 488
++ G++ +R + + I ++ G+ + +TV++Q++ S EN A VTAL T
Sbjct: 444 ILGQGLMIRYRGEQYNWGYQIMPQIIVGIGGGVIANLLTVAVQTVVSTENFAIVTALVST 503
Query: 489 IYRIXXXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYGSPFDFILDYPWGTPMRDAM 548
+ I IW ++ K+L K + D L Y GT R+A+
Sbjct: 504 VTPIGGAVGSAISGAIWNSVMPKRLEKNLPSDLKDQAYTIFESLTVQLSYTRGTDARNAI 563
Query: 549 VESYRYVQKYEVLVALIFTVPMFILSMFLRDPPLT 583
+ SY VQK VA F M F+ +P L+
Sbjct: 564 ILSYSEVQKILTSVATGFAGAMIFPVWFVANPRLS 598
>SPAC1F8.03c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 630
Score = 139 bits (349), Expect = 2e-32
Identities = 112/485 (23%), Positives = 189/485 (38%), Gaps = 8/485 (1%)
Query: 73 SVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXXXXXVIGASAQVFFARLSDVFGR 132
++ CS+ + S Y YAT +I + + + SD+ R
Sbjct: 90 AILACSWASAIQSSTTYSYQVYATASFNRTSMISTLEIATAIISSVCKPILGKFSDITSR 149
Query: 133 LTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXXXXXXXXXSDFSSLRWRLF 192
+ +FY +G I+ + + + Y G+VF + D +SL+WR F
Sbjct: 150 PMTYTLVLLFYVIGFIVVASSSTISAYVIGSVFISIGSSGLDYLNTLVVGDLTSLKWRGF 209
Query: 193 YTFVPSWPFIINMWVSGNVVNAANPLENWSWSIGMWAFIFPLTCLPLVCCILHMRYRASK 252
T + S P+I +W +G +V NW W GM+A I P P V ++++ +A+K
Sbjct: 210 MTALLSTPYIATVWFTGFIVQGIID-SNWRWGYGMFAIIMPAVMTPAVIILMYLERQANK 268
Query: 253 TEAWRHL---QLEKTYYQSHGLLQTLIQLFWKLDXXXXXXXXXXXXCILVPLTLAGGVSQ 309
E + + Q E+ Q L + ++D +L+P +L
Sbjct: 269 DENIKKIINYQTEEKNKNKQSKWQKLWKAVLEVDLFGLILLGVGWSILLLPFSLTSYAKN 328
Query: 310 KWNNPHVIAPFVLGFVLLPIFVVWESKWALDPIAPFELLKDRGVWSALTIQFLIYFVYQM 369
W NP +IA V+G V+L + +E A P P ++ +R +A+ I F Y +
Sbjct: 329 GWKNPSMIAMMVVGGVILIAYSGYEMFIAPYPSCPRRVM-NRTFITAVIIDFFYYLAGYL 387
Query: 370 AVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALVVTRSKRLKPYIITGCSLWM 429
Y T I D S T + + V F + R K I G + +
Sbjct: 388 QSMYFTTYTWILYDWSYRDWTYFNNTMTIALCVFGVFAGAMHRVFHRYKYLQIIGLVIKI 447
Query: 430 VAMGILYHFRSGKDSDKGIIGGLVLWGLTSTLFTYPVTVSLQSITSHENMASVTALNYTI 489
V GIL + L+L G+ + VS Q+ H+++A ++L
Sbjct: 448 VGYGILIRPNFAATGKVDLAWSLILIGMGGSFSVVGSQVSCQASVPHQDLAIASSLLPLY 507
Query: 490 YRIXXXXXXXXXXXIWTQLLYKKLLKEMNGDATLATAAYG--SPFDFILDYPWGTPMRDA 547
I I++ + K L+E + T Y S I +YP GT +RD
Sbjct: 508 TNIGGAIGAAIASPIFSNKV-PKYLREYLPSSINDTQVYNFYSDSSLIREYPVGTEIRDG 566
Query: 548 MVESY 552
+++Y
Sbjct: 567 AIKAY 571
>SPCC61.01c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 597
Score = 130 bits (326), Expect = 8e-30
Identities = 113/549 (20%), Positives = 227/549 (40%), Gaps = 30/549 (5%)
Query: 53 KTEILAQQYDTWYWKAVLL--FSVFLCSYGYGLDGSVRSVYTTYATNXXXXXXXXXXXXX 110
K E +A TW +++++ ++L S+ L+ YAT+
Sbjct: 52 KAEAIAS---TWSKRSIIVAYLGLYLLSFASSLEQQTTYSLQRYATSNFSAHSNLATINL 108
Query: 111 XXXVIGASAQVFFARLSDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXX 170
++ A + + +DVFGR L +A +G + + + ++Q + + Y
Sbjct: 109 VGNILLAVVRAPMVKAADVFGRSESLSLALGMTVLGYLSLAFSRNIQMFTVAYILYICGQ 168
Query: 171 XXXXXXXXXXXSDFSSLRWRLFYTFVPSWPFIINMWVSGNVVNAANPLENWSWSI--GMW 228
+D SSL R + +P P++ +W+ + A +P +N+ W + G+W
Sbjct: 169 TGLGLLSQLIIADTSSLLNRGILSAIPELPYLATVWIGPVLAQAFHPEKNYGWRLGYGIW 228
Query: 229 AFIFPLTCLPLVCCILHMRYRASKTEAWRHLQLEKTYYQSHGLLQ-------TLIQLFW- 280
AFI P LPL+ L + R +K Y + H L+ L LFW
Sbjct: 229 AFILPTVSLPLLAS-LFLNQRKAKAAG--------LYREHHNLINHSTPEKLRLFYLFWQ 279
Query: 281 KLDXXXXXXXXXXXXCILVPLTLAGGVSQKWNNPHVIAPFVLGFVLLPIFVVWESKWALD 340
+LD +L+P + + V + + L LL ++ K+A
Sbjct: 280 ELDGLGIVLFVSGFTLLLLPFSHSSQVVSPDSTILTLFTITLSIALLVTLCFYDVKYARY 339
Query: 341 PIAPFELLKDRGVWSALTIQFLIYFVYQMAVGYLYTILVIAVDESTTSATRITSVYSFTA 400
P+ + LKDR + + + F + Y + +L + L ++ S ++ +V+ F+
Sbjct: 340 PVFALKSLKDRTILGSCVLIFTYFMSYYIFSNFLTSFLQVSYGLSIDMSSLTLNVFVFSM 399
Query: 401 AVASPFFALVVTRSKRLKPYIITGCSLWMVA-MGILYHFRSGKDSDKGIIGGLVLWGLTS 459
+ ++ R R K ++ ++++ +GI+ + + ++ L+L G+
Sbjct: 400 TTTAILSGFLMKRFGRFKMLLMISVPMYVLGILGIILFGINDNHYTRPLVLVLILAGMGG 459
Query: 460 TLFTYPVTVSLQSITSHENMASVTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLKEMNG 519
L T +++QS++SH + L T + +W++ L +LL ++
Sbjct: 460 GLLTLSAQIAVQSVSSHAKLGMNLTLYLTFSSVGGAFGSAIAGGVWSKRLSSRLLHDLKD 519
Query: 520 DATLATAAYGSPFDFI---LDYPWGTPMRDAMVESYRYVQKYEVLVALIFTVPMFILSMF 576
L S F + L YP GT +R+ + +Y +K ++L+ ++ MF +
Sbjct: 520 H--LPVPEIESIFRDLRTALSYPQGTQIRNIINVAYTATEKDLFHISLVASLFMFAGLVI 577
Query: 577 LRDPPLTDD 585
+RD PL+ +
Sbjct: 578 IRDVPLSTE 586
>YPR198w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 543
Score = 57.8 bits (138), Expect = 5e-08
Identities = 75/396 (18%), Positives = 150/396 (36%), Gaps = 43/396 (10%)
Query: 121 VFFARLSDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXXXXXXXXX 180
+ + RL+++ G L+++ + + +G++I + + + +G V
Sbjct: 61 LLWGRLAEILGTKECLMISVIVFEIGSLISALSNSMATLISGRVVAGFGGSGIESLAFVV 120
Query: 181 XSDFSSLRWRLFYTFVPSWPFIINMWVSGNVVNAANPLENWSWS------IGMWAFIFPL 234
+ R + ++I V + A N +W W IG +AFI
Sbjct: 121 GTSIVRENHRGIMITALAISYVIAEGVGPFIGGAFNEHLSWRWCFYINLPIGAFAFIILA 180
Query: 235 TCLPLVCCILHMRYRASKTEAWRHLQLEKTYYQSHGLL-------QTLIQLFWKLDXXXX 287
C + W +++K +G L T L +KLD
Sbjct: 181 FC---------NTSGEPHQKMWLPSKIKKIMNYDYGELLKASFWKNTFEVLVFKLDMVGI 231
Query: 288 XXXXXXXXCILVPLTLAGGVSQKWNNPHVIAPFVLGFVLLPIFVVWESKWA--------- 338
+++ L+ GG + WN+ +I F +G +LL +F ++ +
Sbjct: 232 ILSSAGFTLLMLGLSF-GGNNFPWNSGIIICFFTVGPILLLLFCAYDFHFLSLSGLHYDN 290
Query: 339 --LDPIAPFELLKDRGVWSALTIQFLIYFVYQMAVGYLYTILVIAVDESTTSATRITSVY 396
+ P+ + + + G++++ FL F Y++ YL + + + T A+
Sbjct: 291 KRIKPLLTWNIASNCGIFTSSITGFLSCFAYELQSAYLVQLYQLVFKKKPTLASIHLWEL 350
Query: 397 SFTAAVASPFFALVVTRSKRLKPYIITGCSLWMVAMGILYHFRSGKDSDKGIIGGLVLWG 456
S A +A+ A + ++ +KP I+ G +V G L+ +G+ S IG +L G
Sbjct: 351 SIPAMIATMAIAYLNSKYGIIKPAIVFGVLCGIVGSG-LFTLINGELSQS--IGYSILPG 407
Query: 457 LT------STLFTYPVTVSLQSITSHENMASVTALN 486
+ +TL + V ++ VTA N
Sbjct: 408 IAFGSIFQATLLSSQVQITSDDPDFQNKFIEVTAFN 443
>YGR224w [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 613
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/274 (18%), Positives = 104/274 (36%), Gaps = 17/274 (6%)
Query: 258 HLQLEKTYYQSHGLLQTLIQLFWKLDXXXXXXXXXXXXCILVPLTLAGGVSQKWNNPHVI 317
HL K + + +G + ++L + D CIL+ T GG WN+ +I
Sbjct: 273 HLLKIKGFSKLNGWRKPFMELIFMYDIIEFVFCSAGFTCILLAFTF-GGNRYAWNSASII 331
Query: 318 APFVLGFVLL-----------PIFVVWESKWALDPIAPFELLKDRGVWSALTIQFLIYFV 366
F++G VL+ P F + ++ P+ + +K G+++ FL
Sbjct: 332 ILFIIGIVLVVLAGIYDFLVFPKFNIVKATPHYQPLMSWTNIKKPGIFTVNIALFLTCAG 391
Query: 367 YQMAVGYLYTILVIAVDESTTSATRITSVYSFTAAVASPFFALVVTRSKRLKPYIITGCS 426
Y Y+ + ++S A + V + + +++++KP I+
Sbjct: 392 YISQFTYIVQYFQLIYNDSAWRAAVHLVACIISTVVTAILCGAITDKTRQIKPIIVISSI 451
Query: 427 LWMVAMGILYHFRSGKDSDKG----IIGGLVLWGLT-STLFTYPVTVSLQSITSHENMAS 481
+V GIL + ++ I+ G+ GL S++ + + +S T + S
Sbjct: 452 FGVVGAGILTLLNNNANNSAHIGLLILPGVAFGGLAQSSMLASQIQLDKKSPTFRSDFVS 511
Query: 482 VTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLK 515
+T N + +++ KKL K
Sbjct: 512 ITTFNTFCKNLGQALGGVISNTVFSAAAIKKLTK 545
>SPBC12C2.13c [R] KOG0254 Predicted transporter (major facilitator superfamily)
Length = 531
Score = 51.2 bits (121), Expect = 5e-06
Identities = 86/422 (20%), Positives = 156/422 (36%), Gaps = 51/422 (12%)
Query: 114 VIGASAQVFFARLSDVFGRLTLLIVATVFYSVGTIIQSQAYDVQRYAAGAVFYNXXXXXX 173
+ + Q + RLSD+FGR ++ A +++GT + +
Sbjct: 77 ITNTAFQPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGL 136
Query: 174 XXXXXXXXSDFSSLRWRLFYTFVPSWPFIINM-WVSGNVVNAANPL-----ENWSWSIGM 227
SD SLR R +W I N+ W G + PL + W W
Sbjct: 137 GTMSSIISSDIVSLRER------GTWQGITNIVWGIGG--SLGGPLGGLIAQRWGWRTA- 187
Query: 228 WAFIFPLTCLPLVCCILHMRYRASKTEAWRHLQLEKTYYQSHGLLQTLIQLFWKLDXXXX 287
+ F P+ L + AWR ++++ T S+ L + ++D
Sbjct: 188 FHFQVPMGILSTILV------------AWR-VRVKPTVRNSNASLLS------RIDYLGS 228
Query: 288 XXXXXXXXCILVPLTLAGGVSQKWNNPHVIAPFVLGFVLLPIFVVWESKWALDPIAPFEL 347
++V + GG + W +P +I V ++L F E A++PIAP E+
Sbjct: 229 FLLVTGITALVVTFNM-GGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPVEI 287
Query: 348 LKDRGVWSALTIQFLIYF-----VYQMAVGYLYTILVIAVDESTTSATRITSVYSFTAAV 402
L + F F VY++ + + T+L+ S+ + RI Y + +V
Sbjct: 288 LSQPTPLNVCLGNFFNAFCSFVIVYELPLFFETTLLM----PSSEAGVRIFP-YVISTSV 342
Query: 403 ASPFFALVVTRSKRLKPYIITG---CSLWMVAMGILYHFRSGKDSDKGIIG-GLVLWGLT 458
S L + ++ R + +I G + +V+ +L F G + +I L + G +
Sbjct: 343 GSLCSGLYMKKTGRYRNLVIAGFFFMLMGIVSFAVLTSF--GHRTPLILISLCLAMTGCS 400
Query: 459 STLFTYPVTVSLQSITSHENMASVTALNYTIYRIXXXXXXXXXXXIWTQLLYKKLLKEMN 518
+ +++ S + E A T L+Y +L K+L +
Sbjct: 401 YGMNLTSTLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQTTTLSILMKQLASNLK 460
Query: 519 GD 520
D
Sbjct: 461 DD 462
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.325 0.138 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,443,631
Number of Sequences: 60738
Number of extensions: 1274295
Number of successful extensions: 3401
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 3363
Number of HSP's gapped (non-prelim): 13
length of query: 623
length of database: 30,389,216
effective HSP length: 112
effective length of query: 511
effective length of database: 23,586,560
effective search space: 12052732160
effective search space used: 12052732160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)