ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIII4879 good R KOG1382 General function prediction only Multiple inositol polyphosphate phosphatase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIII4879 1729569 1730975 469
(469 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YBR093c [R] KOG1382 Multiple inositol polyphosphate phosphatase 496 e-140
YBR092c [R] KOG1382 Multiple inositol polyphosphate phosphatase 494 e-139
YHR215w [R] KOG1382 Multiple inositol polyphosphate phosphatase 491 e-139
YAR071w [R] KOG1382 Multiple inositol polyphosphate phosphatase 491 e-139
YDL024c [R] KOG1382 Multiple inositol polyphosphate phosphatase 489 e-138
SPBC21H7.03c [R] KOG1382 Multiple inositol polyphosphate phospha... 147 4e-35
SPBC428.03c [R] KOG1382 Multiple inositol polyphosphate phosphatase 143 5e-34
SPBP4G3.02 [R] KOG1382 Multiple inositol polyphosphate phosphatase 140 3e-33
7294096 [R] KOG1382 Multiple inositol polyphosphate phosphatase 62 2e-09
Hs19923761 [R] KOG1382 Multiple inositol polyphosphate phosphatase 60 5e-09
>YBR093c [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 467
Score = 496 bits (1276), Expect = e-140
Identities = 233/442 (52%), Positives = 312/442 (69%), Gaps = 4/442 (0%)
Query: 28 KIGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGAKLS 87
KIGTQ+ +F +L G PY+ +P DYGI+ +PE CE+KQ+Q++ RHGERYP+ S +
Sbjct: 30 KIGTQKDIFPFLGGAGPYYSFPGDYGISRDLPEGCEMKQLQMVGRHGERYPTVSLAKTIK 89
Query: 88 NVYQKLQNYTGALNGSLSFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTH 147
+ + KL NYT NGSLSFLNDD Y F D LE+E T NS D LNPYTGE +A+ H
Sbjct: 90 STWYKLSNYTRQFNGSLSFLNDD-YEFFIRDDDDLEMETTFANSDDVLNPYTGEMNAKRH 148
Query: 148 ARQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEELDNAVKSTHMNIISEDSSSGAN 207
AR F++ YG ++E ++ +FT+NSKR HDTA +F + L + T + +SE S+GAN
Sbjct: 149 ARDFLAQYGYMVENQTSFAVFTSNSKRCHDTAQYFIDGLGDQFNIT-LQTVSEAESAGAN 207
Query: 208 NLSPGYSCLPWDEDENEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSLFVWCGF 267
LS SC WD D N++ +++Y + YL+DIA R T+TDAS+LF WC F
Sbjct: 208 TLSACNSCPAWDYDANDDIVNEYDTTYLDDIAKRLNKENKGLNL--TSTDASTLFSWCAF 265
Query: 268 EISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVELLKQSD 327
E++ KGYSD C+IFT EL+H+SY DL+ YY +GPG+ + K +GS LFNASV+LLKQS+
Sbjct: 266 EVNAKGYSDVCDIFTKDELVHYSYYQDLHTYYHEGPGYDIIKSVGSNLFNASVKLLKQSE 325
Query: 328 ELDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVPFLDHIYRKAWMTPMAARLYTEK 387
DQKVWLSFTHDTDI+N+L T G+ D+ L A VPF+ + + ++W P AR+YTEK
Sbjct: 326 IQDQKVWLSFTHDTDILNFLTTAGIIDDKNNLTAEYVPFMGNTFHRSWYVPQGARVYTEK 385
Query: 388 FQCSNETFVRYTLNDAVIPIESCSSGPGFSCPEKEFYSYAEKKLDGMDFVKACDIKSSSN 447
FQCSN+T+VRY +NDAV+PIE+CS+GPGFSC +FY YAEK++ G DF+K C++ S SN
Sbjct: 386 FQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSN 445
Query: 448 YTSLSFYWDYESVNYNASLLIQ 469
T L+FYWD+ + +YNASLL Q
Sbjct: 446 STELTFYWDWNTTHYNASLLRQ 467
>YBR092c [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 467
Score = 494 bits (1271), Expect = e-139
Identities = 230/442 (52%), Positives = 311/442 (70%), Gaps = 4/442 (0%)
Query: 28 KIGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGAKLS 87
KIGTQE +F +L G PYF +P DYGI+ +PE CE+KQ+Q+LARHGERYP+ SKGA +
Sbjct: 30 KIGTQEDIFPFLGGAGPYFSFPGDYGISRDLPEGCEMKQLQMLARHGERYPTYSKGATIM 89
Query: 88 NVYQKLQNYTGALNGSLSFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTH 147
+ KL NYT NGSLSFLNDD Y F D LE+E T NS + LNPYTGE A+ H
Sbjct: 90 KTWYKLSNYTRQFNGSLSFLNDD-YEFFIRDDDDLEMETTFANSDNVLNPYTGEMDAKRH 148
Query: 148 ARQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEELDNAVKSTHMNIISEDSSSGAN 207
AR+F++ YG + E ++ +F +S+RVHDTA +F + L + + + +SE S+GAN
Sbjct: 149 AREFLAQYGYMFENQTSFPIFAASSERVHDTAQYFIDGLGDQFNIS-LQTVSEAMSAGAN 207
Query: 208 NLSPGYSCLPWDEDENEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSLFVWCGF 267
LS G +C WDED N++ L KY + YL+DIA R T+ DA++LF WC +
Sbjct: 208 TLSAGNACPGWDEDANDDILDKYDTTYLDDIAKRLNKENKGLNL--TSKDANTLFAWCAY 265
Query: 268 EISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVELLKQSD 327
E++ +GYSD C+IFT+ EL+ +SY DL +YQDGPG+ + + +G+ LFNA+++LLKQS+
Sbjct: 266 ELNARGYSDVCDIFTEDELVRYSYGQDLVSFYQDGPGYDMIRSVGANLFNATLKLLKQSE 325
Query: 328 ELDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVPFLDHIYRKAWMTPMAARLYTEK 387
D KVWLSFTHDTDI+NYL T G+ D+ L A VPF+ + + K+W P AR+YTEK
Sbjct: 326 TQDLKVWLSFTHDTDILNYLTTAGIIDDKNNLTAEYVPFMGNTFHKSWYVPQGARVYTEK 385
Query: 388 FQCSNETFVRYTLNDAVIPIESCSSGPGFSCPEKEFYSYAEKKLDGMDFVKACDIKSSSN 447
FQCSN+T+VRY +NDAV+PIE+CS+GPGFSC +FY YAEK++ G DF+K C++ S SN
Sbjct: 386 FQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSN 445
Query: 448 YTSLSFYWDYESVNYNASLLIQ 469
T L+FYWD+ + +YN +LL Q
Sbjct: 446 VTELTFYWDWNTTHYNDTLLKQ 467
>YHR215w [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 467
Score = 491 bits (1264), Expect = e-139
Identities = 227/442 (51%), Positives = 312/442 (70%), Gaps = 4/442 (0%)
Query: 28 KIGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGAKLS 87
KIGTQ +F +L G+ PY+ +P DYGI+ +PE CE+KQVQ++ RHGERYP+ SK +
Sbjct: 30 KIGTQTEIFPFLGGSGPYYSFPGDYGISRDLPESCEMKQVQMVGRHGERYPTVSKAKSIM 89
Query: 88 NVYQKLQNYTGALNGSLSFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTH 147
+ KL NYTG +G+LSFLNDD Y F DT LE+E T NS++ LNPYTGE +A+ H
Sbjct: 90 TTWYKLSNYTGQFSGALSFLNDD-YEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRH 148
Query: 148 ARQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEELDNAVKSTHMNIISEDSSSGAN 207
AR F++ YG ++E ++ +FT+NS R HDTA +F + L + + + ISE S+GAN
Sbjct: 149 ARDFLAQYGYMVENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFNIS-LQTISEAESAGAN 207
Query: 208 NLSPGYSCLPWDEDENEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSLFVWCGF 267
LS +SC WD+D N++ L KY ++YL IA R T++DA++ F WC +
Sbjct: 208 TLSAHHSCPAWDDDVNDDILKKYDTKYLSGIAKRLNKENKGLNL--TSSDANTFFAWCAY 265
Query: 268 EISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVELLKQSD 327
EI+ +GYSD CNIFT EL+ FSY DL YYQ GPG+ + + +G+ LFNASV+LLK+S+
Sbjct: 266 EINARGYSDICNIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESE 325
Query: 328 ELDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVPFLDHIYRKAWMTPMAARLYTEK 387
DQKVWLSFTHDTDI+NYL T+G+ D+ L A VPF+++ + ++W P AR+YTEK
Sbjct: 326 VQDQKVWLSFTHDTDILNYLTTIGIIDDQNNLTAEHVPFMENTFHRSWYVPQGARVYTEK 385
Query: 388 FQCSNETFVRYTLNDAVIPIESCSSGPGFSCPEKEFYSYAEKKLDGMDFVKACDIKSSSN 447
FQCSN+T+VRY +NDAV+PIE+CS+GPGFSC +FY YAEK++ G DF+K C++ S SN
Sbjct: 386 FQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYGYAEKRVAGTDFLKVCNVSSVSN 445
Query: 448 YTSLSFYWDYESVNYNASLLIQ 469
T L+F+WD+ + +YN +LL Q
Sbjct: 446 STELTFFWDWNTKHYNDTLLKQ 467
>YAR071w [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 467
Score = 491 bits (1264), Expect = e-139
Identities = 227/442 (51%), Positives = 312/442 (70%), Gaps = 4/442 (0%)
Query: 28 KIGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGAKLS 87
KIGTQ +F +L G+ PY+ +P DYGI+ +PE CE+KQVQ++ RHGERYP+ SK +
Sbjct: 30 KIGTQTEIFPFLGGSGPYYSFPGDYGISRDLPESCEMKQVQMVGRHGERYPTVSKAKSIM 89
Query: 88 NVYQKLQNYTGALNGSLSFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTH 147
+ KL NYTG +G+LSFLNDD Y F DT LE+E T NS++ LNPYTGE +A+ H
Sbjct: 90 TTWYKLSNYTGQFSGALSFLNDD-YEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRH 148
Query: 148 ARQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEELDNAVKSTHMNIISEDSSSGAN 207
AR F++ YG ++E ++ +FT+NS R HDTA +F + L + + + ISE S+GAN
Sbjct: 149 ARDFLAQYGYMVENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFNIS-LQTISEAESAGAN 207
Query: 208 NLSPGYSCLPWDEDENEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSLFVWCGF 267
LS +SC WD+D N++ L KY ++YL IA R T++DA++ F WC +
Sbjct: 208 TLSAHHSCPAWDDDVNDDILKKYDTKYLSGIAKRLNKENKGLNL--TSSDANTFFAWCAY 265
Query: 268 EISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVELLKQSD 327
EI+ +GYSD CNIFT EL+ FSY DL YYQ GPG+ + + +G+ LFNASV+LLK+S+
Sbjct: 266 EINARGYSDICNIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESE 325
Query: 328 ELDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVPFLDHIYRKAWMTPMAARLYTEK 387
DQKVWLSFTHDTDI+NYL T+G+ D+ L A VPF+++ + ++W P AR+YTEK
Sbjct: 326 VQDQKVWLSFTHDTDILNYLTTIGIIDDKNNLTAEHVPFMENTFHRSWYVPQGARVYTEK 385
Query: 388 FQCSNETFVRYTLNDAVIPIESCSSGPGFSCPEKEFYSYAEKKLDGMDFVKACDIKSSSN 447
FQCSN+T+VRY +NDAV+PIE+CS+GPGFSC +FY YAEK++ G DF+K C++ S SN
Sbjct: 386 FQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSN 445
Query: 448 YTSLSFYWDYESVNYNASLLIQ 469
T L+F+WD+ + +YN +LL Q
Sbjct: 446 STELTFFWDWNTKHYNDTLLKQ 467
>YDL024c [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 468
Score = 489 bits (1260), Expect = e-138
Identities = 232/441 (52%), Positives = 312/441 (70%), Gaps = 4/441 (0%)
Query: 29 IGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGAKLSN 88
IG+Q+ LF +L G+APYF +P +YGI IPE C L QVQ++ RHGERYP++S+ +
Sbjct: 32 IGSQKSLFPFLGGSAPYFSFPANYGIPTDIPEGCRLTQVQMIGRHGERYPTRSEAKDIFE 91
Query: 89 VYQKLQNYTGALNGSLSFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTHA 148
V+ K+ NYTG GSLSFLN+ Y F D S LE+E T +NS+D LNPYTGE +A+ HA
Sbjct: 92 VWYKISNYTGKYEGSLSFLNN-GYEFFIPDESLLEMETTLQNSIDVLNPYTGEMNAKRHA 150
Query: 149 RQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEELDNAVKSTHMNIISEDSSSGANN 208
R+F++ YG L+E + +FTTNSKR++DTA +FAE L + + + +SE+SSSGAN
Sbjct: 151 REFLAKYGKLMENCTNFPIFTTNSKRIYDTAQYFAEALGDGFNIS-LQTLSENSSSGANT 209
Query: 209 LSPGYSCLPWDEDENEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSLFVWCGFE 268
L+ SC W+ + N + L YS +YLE+I+DR + DA++LF WC FE
Sbjct: 210 LAAKSSCPNWNSNANNDILMSYSRDYLENISDRLNDENKGLNL--SRKDAAALFSWCAFE 267
Query: 269 ISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVELLKQSDE 328
++ KGYS+ C+IF+ AEL+H+SYE DL +YQ+GPG+ L K IG+ LFNA+V+L++QS
Sbjct: 268 LNAKGYSNICDIFSAAELIHYSYETDLTSFYQNGPGYKLIKSIGANLFNATVKLIRQSAH 327
Query: 329 LDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVPFLDHIYRKAWMTPMAARLYTEKF 388
LDQKVWLSFTHDTDI+NYL T GL D+ + L + VPF DH Y ++W P AR+YTEKF
Sbjct: 328 LDQKVWLSFTHDTDILNYLTTAGLIDDTRNLTTNHVPFRDHSYHRSWYIPQGARVYTEKF 387
Query: 389 QCSNETFVRYTLNDAVIPIESCSSGPGFSCPEKEFYSYAEKKLDGMDFVKACDIKSSSNY 448
QCSN+++VRY +NDAV+PIESCSSGPGFSC E FY YA+ +L G+ F + CD+ S
Sbjct: 388 QCSNDSYVRYVVNDAVVPIESCSSGPGFSCEEGTFYEYAKDRLRGVSFYEDCDVSKVSKE 447
Query: 449 TSLSFYWDYESVNYNASLLIQ 469
L+FYWD+ + YNASL+ Q
Sbjct: 448 KELTFYWDWNTTRYNASLVNQ 468
>SPBC21H7.03c [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 463
Score = 147 bits (370), Expect = 4e-35
Identities = 126/414 (30%), Positives = 194/414 (46%), Gaps = 33/414 (7%)
Query: 19 NYGFSENSKKIGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYP 78
N F + +EHL + PYF G++ PE CE++QV LL RHG R P
Sbjct: 20 NVQFEDYESNFFFKEHLGTLSPYHEPYFD-----GLDSAFPETCEIQQVHLLQRHGSRNP 74
Query: 79 SKSKGAKLSNVYQKLQNYTGAL-NGSL--SFLNDDNYHIFWEDTSQLELEVTSKNSLDPL 135
+ A Q L N+ L NGS+ +F +N F + + V + D L
Sbjct: 75 TGDVTATDVYSSQYLNNFQEKLLNGSIPVNFSYPENPLCFIKQWTP----VIDAENADQL 130
Query: 136 NPYTGEQSARTHARQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEEL--DNAVKST 193
+ G RQ Y L + + ++ T +RV ++A +F L D + T
Sbjct: 131 SS-RGRLELFDLGRQLYQRYYKLFD-SYVYDINTAEQERVVESAKWFTYGLFGDKMYEKT 188
Query: 194 HMNIISEDSSSGANNLSPGYSCLPWDEDEN------EEYLSKYSSEYLEDIADRXXXXXX 247
+ +ISE ++GAN+LS Y+ P +D N + + + + ++E I +R
Sbjct: 189 NFILISEGKAAGANSLSM-YNACPVFKDNNFHKNATDAAHAVWRNIFIEPIVNRLAKYFD 247
Query: 248 XXXXXXTATDASSLFVWCGFEISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSL 307
T D SLF C +EI++K +SD C+IFT +E L+F Y+ DL Y GP
Sbjct: 248 SSYKL-TINDVRSLFYICEYEIAIKDHSDFCSIFTPSEFLNFEYDSDLDQAYGGGPVSEW 306
Query: 308 AKPIGSLLFNASVELLKQ--SDELDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVP 365
A +G N + L+ + + D+KV+L+FTHD++II A +G F + N +P
Sbjct: 307 ASTLGGAYINNLADSLRNVTNPDFDRKVFLAFTHDSNIIPVEAALGFFPDITPQN--PLP 364
Query: 366 FLDHIYRKAWMT----PMAARLYTEKFQCS-NETFVRYTLNDAVIPIESCSSGP 414
+IY + T P A L TE F CS ++ +VR+ +N V P+ C GP
Sbjct: 365 TDKNIYTYSQKTSSFVPFAGNLITELFFCSDSKYYVRHLVNQQVYPLIDCGYGP 418
>SPBC428.03c [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 463
Score = 143 bits (361), Expect = 5e-34
Identities = 116/398 (29%), Positives = 189/398 (47%), Gaps = 27/398 (6%)
Query: 32 QEHLFQYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGAKLSNVYQ 91
++HL + PYF P PE C +KQV LL RHG R P+ A + Q
Sbjct: 33 KDHLGTISVYHEPYFNGP-----TTSFPESCAIKQVHLLQRHGSRNPTGDDTATDVSSAQ 87
Query: 92 KLQNYTGAL-NGSL--SFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTHA 148
+ + L NGS+ +F +N F + + V + D L+ +G
Sbjct: 88 YIDIFQNKLLNGSIPVNFSYPENPLYFVKHWTP----VIKAENADQLSS-SGRIELFDLG 142
Query: 149 RQFISLYGDLLEENSTLELFTTNSKRVHDTAAFFAEEL--DNAVKSTHMNIISEDSSSGA 206
RQ Y +L + + ++ T +RV D+A +F+ + D+ T+ ++ ED S+GA
Sbjct: 143 RQVFERYYELFDTD-VYDINTAAQERVVDSAEWFSYGMFGDDMQNKTNFIVLPEDDSAGA 201
Query: 207 NNLSPGYSCLPW-----DEDENEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSL 261
N+L+ YSC + DE+ E + + + +L+ IA+R T +D SL
Sbjct: 202 NSLAMYYSCPVYEDNNIDENTTEAAHTSWRNVFLKPIANRLNKYFDSGYNL-TVSDVRSL 260
Query: 262 FVWCGFEISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVE 321
+ C +EI+++ SD C++FT +E L+F Y+ DL Y GP A +G N
Sbjct: 261 YYICVYEIALRDNSDFCSLFTPSEFLNFEYDSDLDYAYWGGPASEWASTLGGAYVNNLAN 320
Query: 322 LLKQ--SDELDQKVWLSFTHDTDIINYLATVGLFDN--GKKLNASSVPFLDHIYRKAWMT 377
L++ ++ D+KV+L+FTHD+ II A +G F + + + + + +
Sbjct: 321 NLRKGVNNASDRKVFLAFTHDSQIIPVEAALGFFPDITPEHPLPTDKNIFTYSLKTSSFV 380
Query: 378 PMAARLYTEKFQCS-NETFVRYTLNDAVIPIESCSSGP 414
P A L TE F CS N+ +VR+ +N V P+ C GP
Sbjct: 381 PFAGNLITELFLCSDNKYYVRHLVNQQVYPLTDCGYGP 418
>SPBP4G3.02 [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 453
Score = 140 bits (354), Expect = 3e-33
Identities = 112/404 (27%), Positives = 187/404 (45%), Gaps = 30/404 (7%)
Query: 37 QYLAGNAPYFKYPLDYGINLPIPEHCELKQVQLLARHGERYPSKSKGA----KLSNVYQK 92
++L +PY K P YG ++ P C++KQV L RHG R P+ A ++N Q+
Sbjct: 34 EHLTSRSPYHK-PYFYGPSIDFPTTCKIKQVHTLQRHGSRNPTGGNAAFDAVGIANFQQR 92
Query: 93 LQNYTGALNGSLSFLNDDNYHIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTHARQFI 152
L N + ++ S+S N ++ W +E + ++L +G RQF
Sbjct: 93 LLNGSVPIDYSVSG-NPLSFVPTWTPV----IEAANADALSS----SGRVELFDMGRQFY 143
Query: 153 SLYGDLLEENSTLELFTTNSKRVHDTAAF-----FAEELDNAVKSTHMNIISEDSSSGAN 207
Y +L ST ++T +RV D+A + F E++ N T+ ++SE++++G+N
Sbjct: 144 ERYHELFNA-STYNIYTAAQQRVVDSALWYGYGMFGEDVHNF---TNYILVSENATAGSN 199
Query: 208 NLSPGYSCLPWDEDE-NEEYLSKYSSEYLEDIADRXXXXXXXXXXXXTATDASSLFVWCG 266
+LS +C D D+ L + + Y+ I R T D +L+ C
Sbjct: 200 SLSSYNACPASDADDFTTPALEAWRNVYMPPIRQRLNPYFSNYNL--TNDDILNLYGICS 257
Query: 267 FEISVKGYSDACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLFNASVELLKQS 326
+EI+++ YS+ C +F + L+F YE DL Y G G N+ L+
Sbjct: 258 YEIALQDYSEFCKLFNSVDFLNFEYEGDLSFSYGMGNSVKWGSIFGGAYANSLANSLRSV 317
Query: 327 DELDQKVWLSFTHDTDIINYLATVGLFDNGKKLN--ASSVPFLDHIYRKAWMTPMAARLY 384
+ Q+V+ +FTHD +II +G F + N +S H + + P A L
Sbjct: 318 ENNTQQVFFAFTHDANIIPVETALGFFTDNTPENPLPTSYQVHSHSMKASEFVPFAGNLI 377
Query: 385 TEKFQC-SNETFVRYTLNDAVIPIESCSSGPGFSCPEK-EFYSY 426
TE FQC ++ +VR+ +N+ V P+ C GP + E Y+Y
Sbjct: 378 TELFQCEDSKYYVRHLVNEEVFPLSDCGFGPSNTSDGMCELYAY 421
>7294096 [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 460
Score = 61.6 bits (148), Expect = 2e-09
Identities = 90/421 (21%), Positives = 165/421 (38%), Gaps = 29/421 (6%)
Query: 3 LLLLTIIAIAEGASIYNYGFSENSKKIGTQEHLFQYLAGNAPYFKYPLDYGINLPIPEHC 62
LLLL ++AIA+ +Y FS+++ ++ T+ Q+ + A D +P C
Sbjct: 6 LLLLPLVAIAQD----DYCFSKDTSRLQTR----QFSSKTAYQIVKGTDIDKQYLVPG-C 56
Query: 63 ELKQVQLLARHGERYPSKSKGAKLSNVYQKLQNYTGALNGSLSFLNDDNYHIFWEDTSQL 122
+ +++ + RHG R P KS K S V + N ++ + + D +
Sbjct: 57 QPQKMWIFHRHGTRLPKKSMINKASRVAELRDLIIN--NYQVARTKPETDALCQTDLIAI 114
Query: 123 ELEVTSKNSLDPLNPY---TGEQSARTHARQFISLYGDLLEENSTLELFTTNSKRVHDTA 179
+L + + + Y G + R A+ + Y +L N T +R ++
Sbjct: 115 KLWKWNSSITPDMEEYLTAQGYEDLRGTAKLYQRYYPTVLTANYN----DTYYQRTTESF 170
Query: 180 AFFAEELDNAVKSTH-MNIISEDSSSGANNLSPGYSCLPWDEDENEEYLSKYSSEYLEDI 238
FAE L + + H + I +D + + + + ++ +E Y S Y + +
Sbjct: 171 KAFAEGLFGSQNAAHPVEIPKQDLLLRPYDYCSSFKNVNYKDEGSEYYKFHQSKLYNDTL 230
Query: 239 ADRXXXXXXXXXXXXTATDASSLFVWCGFE--ISVKGYSDACNIFTDAELLHFSYEDDLY 296
AD D ++ C +E +V S C F ++ F Y +DL
Sbjct: 231 AD--ISTRLGFLYTLEEADIKLMYDMCRYEQAWNVDRNSVWCGAFLPEQITVFEYLEDLK 288
Query: 297 DYYQDGPGHSLAKPIGSLLFNASVELLKQSDELDQKVWLSFTHDTDIINYLATVGLFDNG 356
YY G G + L + L S+ + V F H T ++ L +G+ +
Sbjct: 289 YYYGSGYGFPENAHLNCRLVQDLLTHL--SNPVSPHVVAHFGHSTGLLTLLTALGIQKDD 346
Query: 357 KKLNASSVPFL-DHIYRKAWMTPMAARLYTEKFQCS---NETFVRYTLNDAVIPIESCSS 412
KL A + L ++ + + P AA K+ C + V + LN + ++ CS
Sbjct: 347 IKLRADNYDSLTSRRWKSSLIDPFAANFVAVKYDCPADLDREKVVFFLNQQAVQLDWCSV 406
Query: 413 G 413
G
Sbjct: 407 G 407
>Hs19923761 [R] KOG1382 Multiple inositol polyphosphate phosphatase
Length = 487
Score = 60.5 bits (145), Expect = 5e-09
Identities = 84/386 (21%), Positives = 148/386 (37%), Gaps = 58/386 (15%)
Query: 62 CELKQVQLLARHGERYPSKSKGAKLSNVYQKLQ---------NYTGALNGSLSFLNDDNY 112
C Q+ L RHG RYP+ + KL ++ LQ + TG+ + + + +
Sbjct: 78 CTPVQLVALIRHGTRYPTVKQIRKLRQLHGLLQARGSRDGGASSTGSRDLGAALADWPLW 137
Query: 113 HIFWEDTSQLELEVTSKNSLDPLNPYTGEQSARTHARQFISLYGDLL--EENSTLELFTT 170
+ W D +E G Q R A + SL+ L E L L T+
Sbjct: 138 YADWMDGQLVE---------------KGRQDMRQLALRLASLFPALFSRENYGRLRLITS 182
Query: 171 NSKRVHDTAAFFAEELDNAVKSTHMNIISEDSSSGANNLSPGYSCLPWDEDENEEYLSKY 230
+ R D++A F + L + H + D + L D E++L++
Sbjct: 183 SKHRCMDSSAAFLQGL---WQHYHPGLPPPDVADMEFGPPTVNDKLMRFFDHCEKFLTEV 239
Query: 231 SSEY--------------LEDIADRXXXXXXXXXXXXTATDASSLFVWCGFEISVKGY-S 275
+++I + A F C F++++KG S
Sbjct: 240 EKNATALYHVEAFKTGPEMQNILKKVAATLQVPVNDLNADLIQVAFFTCSFDLAIKGVKS 299
Query: 276 DACNIFTDAELLHFSYEDDLYDYYQDGPGHSLAKPIGSLLF-------NASVELLKQSDE 328
C++F + Y +DL Y++ G G+++ LF + +VE ++S
Sbjct: 300 PWCDVFDIDDAKVLEYLNDLKQYWKRGYGYTINSRSSCTLFQDIFQHLDKAVEQKQRSQP 359
Query: 329 LDQKVWLSFTHDTDIINYLATVGLFDNGKKLNASSVPFLDH-IYRKAWMTPMAARLYTEK 387
+ V L F H ++ L+ +G F + + L A + H +R + P A+ L
Sbjct: 360 ISSPVILQFGHAETLLPLLSLMGYFKDKEPLTAYNYKKQMHRKFRSGLIVPYASNLIFVL 419
Query: 388 FQCSN-----ETF-VRYTLNDAVIPI 407
+ C N E F V+ LN+ V+P+
Sbjct: 420 YHCENAKTPKEQFRVQMLLNEKVLPL 445
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,243,084
Number of Sequences: 60738
Number of extensions: 1287424
Number of successful extensions: 3328
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3289
Number of HSP's gapped (non-prelim): 12
length of query: 469
length of database: 30,389,216
effective HSP length: 110
effective length of query: 359
effective length of database: 23,708,036
effective search space: 8511184924
effective search space used: 8511184924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)