ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0265 good C KOG1317 Energy production and conversion Fumarase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0265 83648 85123 492
(492 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YPL262w [C] KOG1317 Fumarase 753 0.0
At2g47510 [C] KOG1317 Fumarase 637 0.0
At5g50950 [C] KOG1317 Fumarase 637 0.0
Hs19743875 [C] KOG1317 Fumarase 624 e-179
CE11580 [C] KOG1317 Fumarase 619 e-177
7294726 [C] KOG1317 Fumarase 561 e-160
7290741 [C] KOG1317 Fumarase 557 e-158
7290740 [C] KOG1317 Fumarase 426 e-119
Hs18581352 [I] KOG1170 Diacylglycerol kinase 282 7e-76
SPCC18.18c [C] KOG1317 Fumarase 81 3e-15
>YPL262w [C] KOG1317 Fumarase
Length = 488
Score = 753 bits (1944), Expect = 0.0
Identities = 377/462 (81%), Positives = 416/462 (89%)
Query: 30 SYRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIGGPRERMPEPIVKAFGVLKKSAAVVNE 89
S+R ETDAFGEI VP+DKYWGAQTQRS QNFKIGG RERMP P+V AFGVLKKSAA+VNE
Sbjct: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86
Query: 90 RLGTLDPEIAKPIKQAADEVAQGKLMEHFPLVVFQTGSGTQSNMNANEVISNRAIELIGG 149
LG LDP+I+K I+QAADEVA GKL +HFPLVVFQTGSGTQSNMNANEVISNRAIE++GG
Sbjct: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
Query: 150 ELGSKKIHPNNHCNQAQSSNDTFPSVMHIAAVTEITHHLLPELEGLKVALKQKSDEFQHI 209
++GSK++HPNNHCNQ+QSSNDTFP+VMHIAA +I + L+PEL LK AL+ KS EF HI
Sbjct: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206
Query: 210 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIARVKQSLYHLKFLAQGGTAVGTGLNTKVG 269
VKIGRTHLQDATPLTLGQEFSGYVQQVENGI RV SL L FLAQGGTAVGTGLNTK G
Sbjct: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
Query: 270 FAEDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLGSG 329
F IAEQ+SKETG+ F+TAPNKFEALAAHDA+VE SGALNTLA SLFKIA DIRYLGSG
Sbjct: 267 FDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSG 326
Query: 330 PRCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELNVF 389
PRCGY EL LPENEPGSSIMPGKVNPTQNEA+TQVCVQVMGN+AAITFAG+ GQFELNVF
Sbjct: 327 PRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVF 386
Query: 390 KPVMISNLLSSIRLLGDASNSFRIHCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDAA 449
KPVMI+NLL+SIRL+ DA+ SFR+HCVEGIKANE RI +LL +SLMLVTALNPKIGYDAA
Sbjct: 387 KPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAA 446
Query: 450 SKVAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKMIGPK 491
SKVAKNAHKKGITLKESALEL VL+ +EFD+WV+PE M+GPK
Sbjct: 447 SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488
>At2g47510 [C] KOG1317 Fumarase
Length = 492
Score = 637 bits (1643), Expect = 0.0
Identities = 333/489 (68%), Positives = 383/489 (78%), Gaps = 3/489 (0%)
Query: 6 IVSRGLAQTRVSAKVNRLASLRM--VSYRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIG 63
+ SR L+ + SLR S+R E D FG IQVPSDK WGAQTQRSLQNF+IG
Sbjct: 5 VASRRLSGGTTVTALRYATSLRSYSTSFREERDTFGPIQVPSDKLWGAQTQRSLQNFEIG 64
Query: 64 GPRERMPEPIVKAFGVLKKSAAVVNERLGTLDPEIAKPIKQAADEVAQGKLMEHFPLVVF 123
G RERMPEPIV+AFGVLKK AA VN G LDP I K I QAA EVA+GKL +HFPLVV+
Sbjct: 65 GERERMPEPIVRAFGVLKKCAAKVNMEYG-LDPTIGKAIMQAAQEVAEGKLNDHFPLVVW 123
Query: 124 QTGSGTQSNMNANEVISNRAIELIGGELGSKKIHPNNHCNQAQSSNDTFPSVMHIAAVTE 183
QTGSGTQSNMNANEVI+NRA E++G + G K +HPN+H N++QSSNDTFP+VMHIAA TE
Sbjct: 124 QTGSGTQSNMNANEVIANRAAEILGRKRGEKCVHPNDHVNRSQSSNDTFPTVMHIAAATE 183
Query: 184 ITHHLLPELEGLKVALKQKSDEFQHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIARV 243
I L+P L+ L L+ KS EF+ IVKIGRTH QDATPLTLGQEF GY QV+ G+ RV
Sbjct: 184 INSRLIPSLKTLHSTLESKSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVKYGLNRV 243
Query: 244 KQSLYHLKFLAQGGTAVGTGLNTKVGFAEDIAEQVSKETGIDFKTAPNKFEALAAHDAVV 303
+L L LAQGGTAVGTGLNTK GF IA V++ET + F TA NKFEALAAHDA V
Sbjct: 244 TCTLPRLYQLAQGGTAVGTGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAAHDACV 303
Query: 304 EASGALNTLAVSLFKIANDIRYLGSGPRCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQ 363
E SG+LNT+A SL KIANDIR+LGSGPRCG GEL LPENEPGSSIMPGKVNPTQ EA+T
Sbjct: 304 ETSGSLNTIATSLMKIANDIRFLGSGPRCGLGELVLPENEPGSSIMPGKVNPTQCEALTM 363
Query: 364 VCVQVMGNHAAITFAGASGQFELNVFKPVMISNLLSSIRLLGDASNSFRIHCVEGIKANE 423
VC QVMGNH A+T G++G FELNVFKPV+ S LL S+RL+ DAS SF +CV GI+AN
Sbjct: 364 VCAQVMGNHVAVTVGGSNGHFELNVFKPVIASALLHSVRLIADASASFEKNCVRGIEANR 423
Query: 424 DRIAKLLHESLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELKVLSSEEFDQWVI 483
+RI+KLLHESLMLVT+LNPKIGYD A+ VAK AHK+G TLKE+AL L VL++EEFD V+
Sbjct: 424 ERISKLLHESLMLVTSLNPKIGYDNAAAVAKKAHKEGCTLKEAALNLGVLTAEEFDTLVV 483
Query: 484 PEKMIGPKE 492
PEKMIGP +
Sbjct: 484 PEKMIGPSD 492
>At5g50950 [C] KOG1317 Fumarase
Length = 499
Score = 637 bits (1642), Expect = 0.0
Identities = 326/462 (70%), Positives = 376/462 (80%), Gaps = 1/462 (0%)
Query: 31 YRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIGGPRERMPEPIVKAFGVLKKSAAVVNER 90
+R E D FG IQVPSDK WGAQTQRSLQNF+IGG RERMPEPIV+AFGVLKK AA VN
Sbjct: 39 FREERDTFGPIQVPSDKLWGAQTQRSLQNFEIGGDRERMPEPIVRAFGVLKKCAAKVNME 98
Query: 91 LGTLDPEIAKPIKQAADEVAQGKLMEHFPLVVFQTGSGTQSNMNANEVISNRAIELIGGE 150
G LDP I + I +AA EVA+GKL +HFPLVV+QTGSGTQSNMNANEVI+NRA E++G +
Sbjct: 99 YG-LDPMIGEAIMEAAQEVAEGKLNDHFPLVVWQTGSGTQSNMNANEVIANRAAEILGHK 157
Query: 151 LGSKKIHPNNHCNQAQSSNDTFPSVMHIAAVTEITHHLLPELEGLKVALKQKSDEFQHIV 210
G K +HPN+H N++QSSNDTFP+VMHIAA TEIT L+P L+ L +L+ KS EF+ IV
Sbjct: 158 RGEKIVHPNDHVNRSQSSNDTFPTVMHIAAATEITSRLIPSLKNLHSSLESKSFEFKDIV 217
Query: 211 KIGRTHLQDATPLTLGQEFSGYVQQVENGIARVKQSLYHLKFLAQGGTAVGTGLNTKVGF 270
KIGRTH QDATPLTLGQEF GY QVE G+ RV +L + LAQGGTAVGTGLNTK GF
Sbjct: 218 KIGRTHTQDATPLTLGQEFGGYATQVEYGLNRVACTLPRIYQLAQGGTAVGTGLNTKKGF 277
Query: 271 AEDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLGSGP 330
IA V++ET + F TA NKFEALAAHDA VE SG+LNT+A SL KIANDIR+LGSGP
Sbjct: 278 DVKIAAAVAEETNLPFVTAENKFEALAAHDACVETSGSLNTIATSLMKIANDIRFLGSGP 337
Query: 331 RCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELNVFK 390
RCG GELSLPENEPGSSIMPGKVNPTQ EA+T VC QVMGNH A+T G++G FELNVFK
Sbjct: 338 RCGLGELSLPENEPGSSIMPGKVNPTQCEALTMVCAQVMGNHVAVTIGGSNGHFELNVFK 397
Query: 391 PVMISNLLSSIRLLGDASNSFRIHCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDAAS 450
PV+ S LL SIRL+ DAS SF +CV GI+AN +RI+KLLHESLMLVT+LNPKIGYD A+
Sbjct: 398 PVIASALLHSIRLIADASASFEKNCVRGIEANRERISKLLHESLMLVTSLNPKIGYDNAA 457
Query: 451 KVAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKMIGPKE 492
VAK AHK+G TLK +A++L VL+SEEFD V+PEKMIGP +
Sbjct: 458 AVAKRAHKEGCTLKHAAMKLGVLTSEEFDTLVVPEKMIGPSD 499
>Hs19743875 [C] KOG1317 Fumarase
Length = 510
Score = 624 bits (1610), Expect = e-179
Identities = 315/463 (68%), Positives = 378/463 (81%), Gaps = 2/463 (0%)
Query: 30 SYRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIGGPRERMPEPIVKAFGVLKKSAAVVNE 89
S+R+E D FGE++VP+DKY+GAQT RS NFKIGG ERMP P++KAFG+LK++AA VN+
Sbjct: 49 SFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQ 108
Query: 90 RLGTLDPEIAKPIKQAADEVAQGKLMEHFPLVVFQTGSGTQSNMNANEVISNRAIELIGG 149
G LDP+IA I +AADEVA+GKL +HFPLVV+QTGSGTQ+NMN NEVISNRAIE++GG
Sbjct: 109 DYG-LDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGG 167
Query: 150 ELGSK-KIHPNNHCNQAQSSNDTFPSVMHIAAVTEITHHLLPELEGLKVALKQKSDEFQH 208
ELGSK +HPN+H N++QSSNDTFP+ MHIAA E+ LLP L+ L AL KS EF
Sbjct: 168 ELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQ 227
Query: 209 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIARVKQSLYHLKFLAQGGTAVGTGLNTKV 268
I+KIGRTH QDA PLTLGQEFSGYVQQV+ + R+K ++ + LA GGTAVGTGLNT++
Sbjct: 228 IIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRI 287
Query: 269 GFAEDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLGS 328
GFAE +A +V+ TG+ F TAPNKFEALAAHDA+VE SGA+NT A SL KIANDIR+LGS
Sbjct: 288 GFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGS 347
Query: 329 GPRCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELNV 388
GPR G GEL LPENEPGSSIMPGKVNPTQ EAMT V QVMGNH A+T G++G FELNV
Sbjct: 348 GPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNV 407
Query: 389 FKPVMISNLLSSIRLLGDASNSFRIHCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDA 448
FKP+MI N+L S RLLGDAS SF +CV GI+AN +RI KL++ESLMLVTALNP IGYD
Sbjct: 408 FKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDK 467
Query: 449 ASKVAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKMIGPK 491
A+K+AK AHK G TLKE+A+EL L++E+FD+WV P+ M+GPK
Sbjct: 468 AAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK 510
>CE11580 [C] KOG1317 Fumarase
Length = 501
Score = 619 bits (1597), Expect = e-177
Identities = 319/500 (63%), Positives = 385/500 (76%), Gaps = 13/500 (2%)
Query: 1 MLRNSIVSRGLAQTRVSAKVNRLASLR--------MVSYRVETDAFGEIQVPSDKYWGAQ 52
ML+ +++RG A V A+ LA+ R M R E D FGE++VP+DKY+GAQ
Sbjct: 6 MLQGEMLARGGA---VIARGASLATARNFSRTTVPMAKIRKERDTFGELEVPADKYYGAQ 62
Query: 53 TQRSLQNFKIGGPRERMPEPIVKAFGVLKKSAAVVNERLGTLDPEIAKPIKQAADEVAQG 112
T RS NFKIGGP ERMP P++ AFG+LKK+AA+VN G LD ++A I QAADEV G
Sbjct: 63 TARSQMNFKIGGPEERMPIPVIHAFGILKKAAALVNTEFG-LDKKLADAISQAADEVVDG 121
Query: 113 KLMEHFPLVVFQTGSGTQSNMNANEVISNRAIELIGGELGSKK-IHPNNHCNQAQSSNDT 171
KL EHFPLV +QTGSGTQSNMN NEVISNRAIE++GGELGSKK +HPN+H N +QSSNDT
Sbjct: 122 KLDEHFPLVTWQTGSGTQSNMNVNEVISNRAIEILGGELGSKKPVHPNDHVNMSQSSNDT 181
Query: 172 FPSVMHIAAVTEITHHLLPELEGLKVALKQKSDEFQHIVKIGRTHLQDATPLTLGQEFSG 231
FP+ MHIA E+ LLP L+ L+ AL K++EF+ I+KIGRTH QDA PLTLGQEFS
Sbjct: 182 FPTAMHIAVGREVNSRLLPALKKLRTALHNKAEEFKDIIKIGRTHTQDAVPLTLGQEFSA 241
Query: 232 YVQQVENGIARVKQSLYHLKFLAQGGTAVGTGLNTKVGFAEDIAEQVSKETGIDFKTAPN 291
YV Q++N IARV+ +L L LA GGTAVGTGLNT+ GFAE +A VS+ TG+ F TAPN
Sbjct: 242 YVTQLDNSIARVESTLPRLYQLAAGGTAVGTGLNTRKGFAEKVAATVSELTGLPFVTAPN 301
Query: 292 KFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLGSGPRCGYGELSLPENEPGSSIMPG 351
KFEALAAHDA+VE GALNT+AVS KI NDIR+LGSGPRCG GELSLPENEPGSSIMPG
Sbjct: 302 KFEALAAHDALVEVHGALNTVAVSFMKIGNDIRFLGSGPRCGLGELSLPENEPGSSIMPG 361
Query: 352 KVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELNVFKPVMISNLLSSIRLLGDASNSF 411
KVNPTQ EA+T V QVMGN A++ G++G FELNVFKP+++ N+L S RLL D++ SF
Sbjct: 362 KVNPTQCEAITMVAAQVMGNQVAVSVGGSNGHFELNVFKPLIVRNVLQSTRLLADSAVSF 421
Query: 412 RIHCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELK 471
HCV+GI AN+D IAK++ ESLMLVTALNP IGYD A+K+AK AHK G TL + A++L
Sbjct: 422 TDHCVDGIVANKDNIAKIMRESLMLVTALNPHIGYDNAAKIAKTAHKNGTTLVQEAVKLG 481
Query: 472 VLSSEEFDQWVIPEKMIGPK 491
+L+ E+F QWV PE M+GPK
Sbjct: 482 ILTEEQFAQWVKPENMLGPK 501
>7294726 [C] KOG1317 Fumarase
Length = 470
Score = 561 bits (1447), Expect = e-160
Identities = 280/471 (59%), Positives = 361/471 (76%), Gaps = 5/471 (1%)
Query: 23 LASLRMVSYRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIGGPRERMPEPIVKAFGVLKK 82
++S + V R E+D G ++VP D+Y+GAQT R L NF+IGG ERMP I++A G+LKK
Sbjct: 1 MSSTKKVETRQESDTLGPMEVPMDRYYGAQTMRCLINFRIGGEEERMPRQIIQAMGILKK 60
Query: 83 SAAVVNERLGTLDPEIAKPIKQAADEVAQGKLME--HFPLVVFQTGSGTQSNMNANEVIS 140
+AA N+ G LDP+++ I AAD+V GKL + HFPL ++QTGSGTQSNMN+NEVI
Sbjct: 61 AAAETNQEFG-LDPKLSTAISNAADDVISGKLYDEGHFPLPIWQTGSGTQSNMNSNEVIG 119
Query: 141 NRAIELIGGELGSKK-IHPNNHCNQAQSSNDTFPSVMHIAAVTEITHHLLPELEGLKVAL 199
NRAIEL+GG +G+K +HPN+H N++QSSNDTFPS +HIA T +T L P + L+ +L
Sbjct: 120 NRAIELLGGRIGTKDPVHPNDHVNKSQSSNDTFPSAIHIAVATALTKDLRPAVTALRDSL 179
Query: 200 KQKSDEFQHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIARVKQSLYHLKFLAQGGTA 259
+ KS+E++ I+KIGRTH QDA PLTLGQEFSGY QQ+ NG+ R+ L + LA GGTA
Sbjct: 180 QAKSNEWKDIIKIGRTHTQDAVPLTLGQEFSGYAQQLTNGLQRIDAVLPRVYQLALGGTA 239
Query: 260 VGTGLNTKVGFAEDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKI 319
VGTGLNT+ GFAE +++++ +G+ F APN FEALA DA+VE GALN LAVSL K+
Sbjct: 240 VGTGLNTRRGFAEKCVKRIAQLSGLPFVVAPNFFEALACRDAMVEVHGALNVLAVSLMKV 299
Query: 320 ANDIRYLGSGPRCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAG 379
NDIR+LGSGPRCG GEL LPENEPGSSIMPGKVNPTQ EAMT +C QVMGNH A++ G
Sbjct: 300 TNDIRFLGSGPRCGLGELFLPENEPGSSIMPGKVNPTQCEAMTMICAQVMGNHVAVSVGG 359
Query: 380 ASGQFELNVFKPVMISNLLSSIRLLGDASNSFRIHCVEGIKANEDRIAKLLHESLMLVTA 439
A+G FELNVFKP++ SN+L SI+LL D SF +CV+GIK N++++AK+++ESLMLVTA
Sbjct: 360 ANGHFELNVFKPLIASNVLRSIKLLADGCISFNCNCVKGIKPNKEKLAKIVNESLMLVTA 419
Query: 440 LNPKIGYDAASKVAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKMIGP 490
LNP IGYD ++++AK AHK G TLK AL + S ++F++WV PEKM+GP
Sbjct: 420 LNPHIGYDKSAQIAKAAHKNGTTLKVEALNAGI-SEKDFNEWVRPEKMLGP 469
>7290741 [C] KOG1317 Fumarase
Length = 523
Score = 557 bits (1435), Expect = e-158
Identities = 286/484 (59%), Positives = 364/484 (75%), Gaps = 25/484 (5%)
Query: 31 YRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIGGPRERMPEPIVKAFGVLKKSAAVVNER 90
+R E D FGE++VP+DK +GAQT RS NF IG ERMP P+++A G+LKK+ A VN+
Sbjct: 42 FRTEKDTFGELKVPADKLYGAQTMRSKLNFPIGDIGERMPMPVIQAMGILKKACAEVNKD 101
Query: 91 LGTLDPEIAKPIKQAADEVAQGKLME--HFPLVVFQTGSGTQSNMNANEVISNRAIELIG 148
G LD +++ + A D+V GKL + HFPLV++QTGSGTQ+NMN NEVISN AI+++G
Sbjct: 102 YG-LDGKVSDAVSCACDDVISGKLYKQGHFPLVIWQTGSGTQTNMNTNEVISNAAIKMMG 160
Query: 149 GELGSKK-IHPNNHCNQAQSSNDTFPSVMHIAAVTEITHHLLPELEGLKVALKQKSDEFQ 207
GELGSKK +HPN+H N++QSSNDTFP+ +HI+ E+ L+P + L+ ALK KSDEF+
Sbjct: 161 GELGSKKPVHPNDHVNKSQSSNDTFPTAIHISVGMELNERLVPAVTHLRDALKSKSDEFK 220
Query: 208 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIARVKQSLYHLKFLAQGGTAVGTGLNTK 267
I+KIGRTHL DA PLTLGQEFSGY QQ+ NG+ R+K L + LA GGTAVGTGLNT+
Sbjct: 221 DIIKIGRTHLMDAVPLTLGQEFSGYTQQLTNGLERIKGCLPRVYELALGGTAVGTGLNTR 280
Query: 268 VGFAEDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLG 327
GFAE +A+++S+ T + F +APNKFEALAA DA+VE G LNT+AVSL KIANDIR LG
Sbjct: 281 KGFAEKVAKRISELTCLPFVSAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRLLG 340
Query: 328 SGPRCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELN 387
SGPRCG GEL LPENEPGSSIMPGKVNPTQ E+MT +C QVMGN A+T G++G FELN
Sbjct: 341 SGPRCGLGELMLPENEPGSSIMPGKVNPTQCESMTMLCAQVMGNQVAVTIGGSNGHFELN 400
Query: 388 VFKPVMISNLLSSIRLLG--------------------DASNSFRIHCVEGIKANEDRIA 427
VFKP+++SN+L SIRLLG D S +F +CVEG++AN++RI
Sbjct: 401 VFKPLVVSNVLRSIRLLGESEMCFPSGKTCIHNLLLPADGSMTFSKNCVEGLQANKERID 460
Query: 428 KLLHESLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKM 487
K+++ESLMLVTALNP IGYD A+ +AK AHK TLKE AL+ + + E+F +WV P++M
Sbjct: 461 KIMNESLMLVTALNPHIGYDKAALIAKTAHKNKTTLKEEALKTGI-TEEQFKEWVNPKEM 519
Query: 488 IGPK 491
+GPK
Sbjct: 520 LGPK 523
>7290740 [C] KOG1317 Fumarase
Length = 396
Score = 426 bits (1096), Expect = e-119
Identities = 237/462 (51%), Positives = 300/462 (64%), Gaps = 72/462 (15%)
Query: 31 YRVETDAFGEIQVPSDKYWGAQTQRSLQNFKIGGPRERMPEPIVKAFGVLKKSAAVVNER 90
+RVE+D FGE++VP+DKY+GAQT RS NF IGG ERMP A G+LKK+AA VN+
Sbjct: 6 FRVESDTFGELKVPADKYYGAQTMRSQINFPIGGATERMP-----AMGILKKAAAEVNKE 60
Query: 91 LGTLDPEIAKPIKQAADEVAQGKLMEHFPLVVFQTGSGTQSNMNANEVISNRAIELIGGE 150
G LD +++ E IS A ++I G+
Sbjct: 61 FG-LDSKVS-------------------------------------EAISKAADDVISGK 82
Query: 151 LGSKKIHPNNHCNQAQSSNDTFPSVM-HIAAVTEITHHLLPELEGLKVALKQKSDEFQHI 209
L +D FP V+ + T+ ++ +S+EF+ I
Sbjct: 83 L----------------YDDHFPLVIWQTGSGTQSNMNV------------NESEEFKDI 114
Query: 210 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIARVKQSLYHLKFLAQGGTAVGTGLNTKVG 269
+KIGRTH DA PLTLGQEFSGY QQ+ R+ L + LA GGTAVGTGLNT+ G
Sbjct: 115 IKIGRTHTMDAVPLTLGQEFSGYAQQLAYAQERIDACLPRVYELALGGTAVGTGLNTRKG 174
Query: 270 FAEDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLGSG 329
FAE A ++++ T + F TAPNKFEALAA DA+VE G LNT+AVSL KIANDIR+LGSG
Sbjct: 175 FAEKCAAKIAELTSLPFVTAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRFLGSG 234
Query: 330 PRCGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELNVF 389
PRCG GELSLPENEPGSSIMPGKVNPTQ E++T + QVMGN A+T G++G FELNVF
Sbjct: 235 PRCGLGELSLPENEPGSSIMPGKVNPTQCESLTMLSAQVMGNQVAVTIGGSNGHFELNVF 294
Query: 390 KPVMISNLLSSIRLLGDASNSFRIHCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDAA 449
KP+++SN+L SIRLL D S +F +CV GI+AN + IAK+++ESLMLVTALNP IGYD A
Sbjct: 295 KPLIVSNVLRSIRLLSDGSRTFTANCVNGIQANRENIAKIMNESLMLVTALNPHIGYDKA 354
Query: 450 SKVAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKMIGPK 491
+K+AK AHK G TLKE A+ L L+ ++F+ WV PE+M+GPK
Sbjct: 355 AKIAKTAHKNGTTLKEEAINLGYLTEQQFNDWVRPEQMLGPK 396
>Hs18581352 [I] KOG1170 Diacylglycerol kinase
Length = 1324
Score = 282 bits (722), Expect = 7e-76
Identities = 144/220 (65%), Positives = 172/220 (77%)
Query: 272 EDIAEQVSKETGIDFKTAPNKFEALAAHDAVVEASGALNTLAVSLFKIANDIRYLGSGPR 331
E +A +++ TG+ F TAPNKFEALAAHDA+VE SGA+NT A SL IAN+IR+LGSGP
Sbjct: 1105 EKVAAKLAARTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMTIANNIRFLGSGPW 1164
Query: 332 CGYGELSLPENEPGSSIMPGKVNPTQNEAMTQVCVQVMGNHAAITFAGASGQFELNVFKP 391
G GEL LPENEPGSSIMPGKVNPTQ EAMT V QVMGNH A+T G+SG FELNVFKP
Sbjct: 1165 SGLGELILPENEPGSSIMPGKVNPTQCEAMTMVVAQVMGNHVAVTVGGSSGHFELNVFKP 1224
Query: 392 VMISNLLSSIRLLGDASNSFRIHCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDAASK 451
+MI N+L S RLL DAS SF +CV GI+AN +RI KL++ES MLVTALNP+I YD A+K
Sbjct: 1225 MMIKNVLHSARLLADASVSFTENCVVGIQANTERINKLMNESQMLVTALNPRIAYDKAAK 1284
Query: 452 VAKNAHKKGITLKESALELKVLSSEEFDQWVIPEKMIGPK 491
+AK AHK G TLKE+ +EL L+ E+FD+ V + M+ PK
Sbjct: 1285 IAKTAHKNGSTLKETVIELGYLTPEQFDEQVKTKDMLSPK 1324
>SPCC18.18c [C] KOG1317 Fumarase
Length = 81
Score = 81.3 bits (199), Expect = 3e-15
Identities = 42/79 (53%), Positives = 53/79 (66%)
Query: 414 HCVEGIKANEDRIAKLLHESLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELKVL 473
HCV GI+ N + IA+ L +SLMLVTALNP IGYD +K+AK A K TLK + L
Sbjct: 2 HCVVGIEPNYEGIARHLRDSLMLVTALNPHIGYDNCAKIAKTALKNKSTLKHEFVTLGFG 61
Query: 474 SSEEFDQWVIPEKMIGPKE 492
+ E+FD+WV PE MI K+
Sbjct: 62 TPEQFDEWVRPELMISAKK 80
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,974,107
Number of Sequences: 60738
Number of extensions: 1108698
Number of successful extensions: 2906
Number of sequences better than 1.0e-05: 10
Number of HSP's better than 0.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2876
Number of HSP's gapped (non-prelim): 12
length of query: 492
length of database: 30,389,216
effective HSP length: 110
effective length of query: 382
effective length of database: 23,708,036
effective search space: 9056469752
effective search space used: 9056469752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)