ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0311 good L KOG0966 Replication, recombination and repair ATP-dependent DNA ligase IV
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0311 100161 97441 -907
(907 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YOR005c [L] KOG0966 ATP-dependent DNA ligase IV 732 0.0
SPCC1183.05c [L] KOG0966 ATP-dependent DNA ligase IV 291 3e-78
Hs4504997 [L] KOG0966 ATP-dependent DNA ligase IV 253 9e-67
At5g57160 [L] KOG0966 ATP-dependent DNA ligase IV 183 9e-46
7292907 [L] KOG0966 ATP-dependent DNA ligase IV 171 4e-42
Hs4557719 [L] KOG0967 ATP-dependent DNA ligase I 116 2e-25
YDL164c [L] KOG0967 ATP-dependent DNA ligase I 108 5e-23
ECU02g1220 [L] KOG0967 ATP-dependent DNA ligase I 102 2e-21
At1g49250 [L] KOG0967 ATP-dependent DNA ligase I 100 8e-21
7291668 [L] KOG0967 ATP-dependent DNA ligase I 97 9e-20
Hs7710126 [L] KOG4437 ATP-dependent DNA ligase III 96 2e-19
Hs4504995 [L] KOG4437 ATP-dependent DNA ligase III 96 2e-19
CE05328 [L] KOG0967 ATP-dependent DNA ligase I 85 6e-16
7299616 [L] KOG4437 ATP-dependent DNA ligase III 79 2e-14
SPBC713.06 [L] KOG0967 ATP-dependent DNA ligase I 77 9e-14
CE00757 [L] KOG0966 ATP-dependent DNA ligase IV 77 9e-14
At1g66730_2 [L] KOG0967 ATP-dependent DNA ligase I 71 9e-12
At1g08130 [L] KOG0967 ATP-dependent DNA ligase I 55 4e-07
>YOR005c [L] KOG0966 ATP-dependent DNA ligase IV
Length = 944
Score = 732 bits (1890), Expect = 0.0
Identities = 398/935 (42%), Positives = 570/935 (60%), Gaps = 58/935 (6%)
Query: 5 ENFSPSPEFKWLCDELLGKIYETSSKKHL-IGKPVTVRYLEIITNFIKLWRSTVGNYIYP 63
+NF+PSP+FKWLC+EL KI+E GK + +Y EII+NF+++WR TVGN IYP
Sbjct: 12 QNFAPSPDFKWLCEELFVKIHEVQINGTAGTGKSRSFKYYEIISNFVEMWRKTVGNNIYP 71
Query: 64 ALRLIVPFRDRRIYNVKENTLIKALCRYLRLPKSSETENRLLRWKQRAARGVKLSDFCVE 123
AL L +P+RDRRIYN+K+ LI+ +C YL+LPK+S TE RL WKQR +G LS VE
Sbjct: 72 ALVLALPYRDRRIYNIKDYVLIRTICSYLKLPKNSATEQRLKDWKQRVGKGGNLSSLLVE 131
Query: 124 EIRKRQKDYEGANRITIDELNGYLDEVSQEGNGKRMGYMALTDSRAFNYCLNHMTFMEMK 183
EI KR+ + + ITID +N YLD +S + G+ +L S+ F +C+ +M+F+E+K
Sbjct: 132 EIAKRRAE-PSSKAITIDNVNHYLDSLSGDRFASGRGFKSLVKSKPFLHCVENMSFVELK 190
Query: 184 FFFDIILKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERLRQTDLSITI 243
+FFDI+LK RV+ G E+ L WHPDA DYLSV+SDL V++ +LY+P RL+ DLSI +
Sbjct: 191 YFFDIVLKNRVIGGQEHKLLNCWHPDAQDYLSVISDLKVVTSKLYDPKVRLKDDDLSIKV 250
Query: 244 SHAFEPQLAKRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFS 303
AF PQLAK+ +LSYE++ L DF++EEKMDGER+Q+HY+NYGE IK+ SRRG+D++
Sbjct: 251 GFAFAPQLAKKVNLSYEKICRTLHDDFLVEEKMDGERIQVHYMNYGESIKFFSRRGIDYT 310
Query: 304 YLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELA 363
YLYG + SSG IS L+ +VK+C+LDGEM+T+D ++ ++LPFGLVK SA +
Sbjct: 311 YLYGASLSSGTISQHLRFTDSVKECVLDGEMVTFDAKRRVILPFGLVKGSAKEALSFNSI 370
Query: 364 GIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAE 423
+ PL++ FDL+YLNG SLT L L +RK YL IL+P++ VEI++ + E
Sbjct: 371 N---NVDFHPLYMVFDLLYLNGTSLTPLPLHQRKQYLNSILSPLKNIVEIVRSSRCYGVE 427
Query: 424 AIKDSLEQAISMGSEGIVLKHLHSKYFVGSRNTDWIKIKPEYLEQFGENMDLLIIGREQG 483
+IK SLE AIS+GSEG+VLK+ +S Y V SRN +WIK+KPEYLE+FGEN+DL++IGR+ G
Sbjct: 428 SIKKSLEVAISLGSEGVVLKYYNSSYNVASRNNNWIKVKPEYLEEFGENLDLIVIGRDSG 487
Query: 484 KKDSFFCGLSISDPNEVAEK------------------------PRFISFCTIANGLSNE 519
KKDSF GL + D E + + +SFC+IANG+S E
Sbjct: 488 KKDSFMLGLLVLDEEEYKKHQGDSSEIVDHSSQEKHIQNSRRRVKKILSFCSIANGISQE 547
Query: 520 EFKDIERKTWGKWHIFSEDPPSPNLLGFGTKVPYEWIHPEDSVVLEVKARAIDTKESEKR 579
EFK+I+RKT G W SE P ++L FG+K+P EWI P +S+VLE+K+R++D E+ +
Sbjct: 548 EFKEIDRKTRGHWKRTSEVAPPASILEFGSKIPAEWIDPSESIVLEIKSRSLDNTETNMQ 607
Query: 580 KYRSGCTLHFGYCKQIRYDKDWKTVASFSEFEDMKDARN--FYNKRKSHQVTDGKKRASK 637
KY + CTL+ GYCK+IRYDK+W + ++ + + ++ Y +S K K
Sbjct: 608 KYATNCTLYGGYCKRIRYDKEWTDCYTLNDLYESRTVKSNPSYQAERSQLGLIRK----K 663
Query: 638 RAKIGIVNSSEPTALVAPVSNTFSNCRFRVISDYFDSTKRRRISQEDLCSVILEHGGEIV 697
R ++ I +S P+SN F+ F V+SDY RI++ +L I+EHGG+++
Sbjct: 664 RKRVLISDSFHQNRKQLPISNIFAGLLFYVLSDYVTEDTGIRITRAELEKTIVEHGGKLI 723
Query: 698 YTSDENNLPQDNLYIIGEKLTRECKILLNAKNLIIRPSWIFSC--------IEEGYKTPF 749
Y ++ +I K T ECK L++ I+ P+W+ C IE Y F
Sbjct: 724 YNVILKRHSIGDVRLISCKTTTECKALIDRGYDILHPNWVLDCIAYKRLILIEPNY--CF 781
Query: 750 TESDIFRGELESSMDC--SQFYTDFNTASLNHL----LETANRGIKNPDSDLLLPEVPLF 803
S R E +DC F D + L+ L L G DS+ + PLF
Sbjct: 782 NVSQKMRAVAEKRVDCLGDSFENDISETKLSSLYKSQLSLPPMGELEIDSE--VRRFPLF 839
Query: 804 LFSNLKLAVLNSENVLDTSILEVEFAIKCHGGELVHIENAS--IIIVFNDFISREDLFSL 861
LFSN V + + I+E++ IK GG++ ++ III + D I R+D +
Sbjct: 840 LFSNRIAYVPRRKISTEDDIIEMK--IKLFGGKITDQQSLCNLIIIPYTDPILRKDCMNE 897
Query: 862 RQKIASKAVKESTESTPRIPRMVDISWALDSIKDN 896
+ + +K S ++ P+I R+V W SI +N
Sbjct: 898 VHEKIKEQIKAS-DTIPKIARVVAPEWVDHSINEN 931
>SPCC1183.05c [L] KOG0966 ATP-dependent DNA ligase IV
Length = 923
Score = 291 bits (745), Expect = 3e-78
Identities = 220/755 (29%), Positives = 365/755 (48%), Gaps = 62/755 (8%)
Query: 19 ELLGKIYETSSKKHLIGKPVTVRYLEIITNFIKLWRSTVGNYIYPALRL---IVPFRDRR 75
E L +I +T K P ++ +I+ ++ WR VG +YP LRL I R+R
Sbjct: 30 EPLSRIGKTRKSKTSNLDPYELKR-KILLDYFNKWRQHVGPDLYPLLRLSNLIFLDRERG 88
Query: 76 IYNVKENTLIKALCRYLRLPKSSETENRLLRWKQRAARGVKLSDFCVEEIRKRQKDYEGA 135
Y KE L K R + L +SE L W+ ++ +++I +R+
Sbjct: 89 SYGFKEFGLGKLFIRAMHLSPTSEDAKSLKNWRGSESKHTGDFSTMLQDILQRRAYRTFP 148
Query: 136 NRITIDELNGYLDEVSQEGNGKRMGYMA----LTDSRA--FNYCLNHMTFMEMKFFFDII 189
T+ ++N LD+++ + + ++ + D+R ++ +E+++ I+
Sbjct: 149 GAFTVGDVNALLDQLADASSEYVLNFLPYLTLIRDTRVNILEQFYRSLSPLELRWLIPIL 208
Query: 190 LKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERLRQTDLSITISHAFEP 249
LK R E L+ +HPDA + S L + LY+P+ L +T+ + + F+P
Sbjct: 209 LKVRKYGTSEKFILSVFHPDAARLYRLCSSLKRICWELYDPSRSLDETETDVEVFSCFQP 268
Query: 250 QLA----KRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYL 305
QLA K H + E + +K F IEEK+DGER+Q+H + + ++ SR ++Y
Sbjct: 269 QLANFKKKDLHQTLEAMGNK---PFWIEEKLDGERIQLHMSS--GKFQFYSRNARSYTYA 323
Query: 306 YGEN--SSSGPISPSLKLHFN--VKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSE 361
YG + ++ + F+ + ILDGEM+T+D + V+P+G ++S +
Sbjct: 324 YGSSYFDEQSRLTQYIIGAFDKRISQIILDGEMVTWDPVLETVIPYGSLRSIFEDS---- 379
Query: 362 LAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAIN 421
+ SY P +V FD++YLNGKSL +LE R+ L K++ + I+ Y
Sbjct: 380 ----SSHSSYSPYYVVFDILYLNGKSLVKYSLESRRRILEKVIVRESHRMSILPYKVGST 435
Query: 422 AEAIKDSLEQAISMGSEGIVLKHLHSKYFVGSRNTDWIKIKPEYLEQFGENMDLLII--- 478
E I+ L I GSEG+V+K Y +G R DWIK+KP YL+ FGE++D LI+
Sbjct: 436 IEDIEAELRNVIQEGSEGLVIKKPSGSYHLGERMDDWIKVKPYYLQGFGEDLDCLILGGY 495
Query: 479 ---GREQGKKDSFFCGLSIS-DPNEVAEKPRFISFCTIANGLSNEEFKDIERKTWGKWHI 534
G++ GK +SF CGL + P + +EK F SF + G + + I ++T GKW
Sbjct: 496 FGRGKQSGKINSFLCGLRMDYTPKDHSEK--FQSFVRVGGGFTYFDRDIIRKETEGKWLP 553
Query: 535 FSEDPPSPNLLGFGTKVPYE----WIHPEDSVVLEVKARAIDTKESEKRKYRSGCTLHFG 590
+S D L GTK +E WIHP+DS+VL++KA + K Y TL F
Sbjct: 554 WSSDALEYMELA-GTKQDFEKPDMWIHPKDSLVLQIKAAEVVVSNRFKTNY----TLRFP 608
Query: 591 YCKQIRYDKDWKTVASFSEFEDMKDARNFYNKRKSHQVTDGKKRASKRAKIGIVNSSEPT 650
+++R D+ WK + +EF +K+A + H V +K + KR K EPT
Sbjct: 609 RLEKVRLDRSWKDALTINEFFTLKNAVEKQDNVSFH-VNKKRKVSQKREKQKKFLYDEPT 667
Query: 651 --ALVAPVSNTFSNCRFRVISDYFDSTKRRRISQEDLCSVILEHGGEIVYTSDENNLPQD 708
+P S+ N F V+ ++ L +I+E+GG I N ++
Sbjct: 668 FKKEASPHSDVLKNLHFVVL-----PPTELHETKAGLQQIIIENGGLI--HQGVGNFGKE 720
Query: 709 NLYIIGEKLTRECKILLNAKNL--IIRPSWIFSCI 741
L+++ ++++ I +KN+ IIR W+ +
Sbjct: 721 RLFLVADRVSTRVSI-ERSKNMCTIIRSQWVMDSV 754
>Hs4504997 [L] KOG0966 ATP-dependent DNA ligase IV
Length = 844
Score = 253 bits (646), Expect = 9e-67
Identities = 228/886 (25%), Positives = 397/886 (44%), Gaps = 90/886 (10%)
Query: 65 LRLIVPF--RDRRIYNVKENTLIKALCRYLRLPKSSETENRLLRWKQRAARGVKLSDFCV 122
+RLI+P R+R Y +KE L K L LP+ + +LL ++ DF +
Sbjct: 1 MRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHGDAGDFAM 60
Query: 123 EEIRKRQKDYEGANRITIDELNGYLDEVSQEGNGKRMGYMALTDSRAFNYCLNHMTFMEM 182
+ +TI ++N LD ++ + KR + ++ + + +E
Sbjct: 61 IAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLI----KKSLLQLITQSSALEQ 116
Query: 183 KFFFDIILKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERLRQTDLSIT 242
K+ +I+K L + + +H DA + +V +DL+ + ++L++P+ L +D+SIT
Sbjct: 117 KWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGL--SDISIT 174
Query: 243 ISHAFEPQLAKRTHLSYERVASKLQHD-FIIEEKMDGERLQIHYINYGEQIKYLSRRGVD 301
+ A +P LA + E + ++H F IE K+DGER+Q+H G+ KY SR G +
Sbjct: 175 LFSASKPMLAAIADI--EHIEKDMKHQSFYIETKLDGERMQMH--KDGDVYKYFSRNGYN 230
Query: 302 FSYLYGENSSSGPISPSLKLHF--NVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQ 359
++ +G + + G ++P + F +++ CILDGEM+ Y+ + G +
Sbjct: 231 YTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGT---------K 281
Query: 360 SELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKA 419
++ + + + FD++ +N K L + L +R + L+ I TP+ +EI+Q +A
Sbjct: 282 FDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQA 341
Query: 420 INAEAIKDSLEQAISMGSEGIVLKHLHSKYFVGSRNTDWIKIKPEYLEQFGENMDLLIIG 479
+ D+L +AI EGI++K S Y R W+KIKPEY+ + +D+LI+G
Sbjct: 342 HTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVG 401
Query: 480 REQGK------KDSFFCGLSISDPNEVAEKPR-FISFCTIANGLSNEEFKDIERKTWGKW 532
GK F C ++ P EKP F + + +G + +E D+ K W
Sbjct: 402 GYWGKGSRGGMMSHFLCAVAEKPP--PGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYW 459
Query: 533 HIFSEDPPSPNLLGFGTKVPYEWIHPEDSVVLEVKARAIDTKESEKRKYRSGCTLHFGYC 592
F P ++L GT+ P +I P +SV++++KA I + Y++GCTL F
Sbjct: 460 KPFHRKAPPSSIL-CGTEKPEVYIEPCNSVIVQIKAAEIVPSD----MYKTGCTLRFPRI 514
Query: 593 KQIRYDKDWKTVASFSEFEDMKD-------ARNFYNKRKSHQVTDGKKRASKRAK-IGIV 644
++IR DK+W + + E ++ +++ Y +K A K K IGI+
Sbjct: 515 EKIRDDKEWHECMTLDDLEQLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGII 574
Query: 645 NSSEPTAL--VAPVSNTFSNCRFRVISDYFDSTKRRRISQEDLCSVILEHGGEIVYTSDE 702
+ L V +SN F + F V+S K DL + I E GG IV +
Sbjct: 575 EHLKAPNLTNVNKISNIFEDVEFCVMSGTDSQPK------PDLENRIAEFGGYIV----Q 624
Query: 703 NNLPQDNLYIIGEKLTRECKILLNAKNLIIRPSWIFSCIEEGYKTPFTESDIF------R 756
N P I G + R I+L+ K+ +++P+W+ C + P+ + +
Sbjct: 625 NPGPDTYCVIAGSENIRVKNIILSNKHDVVKPAWLLECFKTKSFVPWQPRFMIHMCPSTK 684
Query: 757 GELESSMDCSQFYTD--FNTASLNHLLETANRGIKNPDSDLLLPEVPLFLFSNLK----- 809
DC Y D F LN L E + GIKN S+ PE L ++L+
Sbjct: 685 EHFAREYDC---YGDSYFIDTDLNQLKEVFS-GIKN--SNEQTPEEMASLIADLEYRYSW 738
Query: 810 ----LAVLNSENV-LDTSILEVEFAIKCHGGEL------VHIENASIIIVFNDFISREDL 858
L++ V LD+ + + + K G L + A ++ + +S +
Sbjct: 739 DCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCLAEGVSHVII 798
Query: 859 FSLRQKIASKAVKESTESTPRIPRMVDISWALDSIKDNYIAETEHY 904
++A K + R +++ SW DSI + E Y
Sbjct: 799 GEDHSRVAD--FKAFRRTFKRKFKILKESWVTDSIDKCELQEENQY 842
>At5g57160 [L] KOG0966 ATP-dependent DNA ligase IV
Length = 1184
Score = 183 bits (465), Expect = 9e-46
Identities = 195/772 (25%), Positives = 330/772 (42%), Gaps = 116/772 (15%)
Query: 62 YPALRLIVPF--RDRRIYNVKENTLIKALCRYLRLPKSSETENRLLRWKQ--RAARGVKL 117
+ A+RLI+P R+R Y +KE+ L L L + + + RLL W++ A G
Sbjct: 44 FVAVRLIIPSLDRERGSYGLKESVLATCLIDALGISRDAPDAVRLLNWRKGGTAKAGANA 103
Query: 118 SDFCV---EEIRKRQKDYEGANRITIDELNGYLDEVSQEGNGKRMGYMALTDSRAFNYCL 174
+F + E +++RQ G +TI ELN LD ++ N + T +
Sbjct: 104 GNFSLIAAEVLQRRQGMASGG--LTIKELNDLLDRLASSENRAEKTLVLST-------LI 154
Query: 175 NHMTFMEMKFFFDIILKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERL 234
EMK+ IILK L E +HPDA D +V DL ++ ++L + ++R
Sbjct: 155 QKTNAQEMKWVIRIILKDLKLGMSEKSIFQEFHPDAEDLFNVTCDLKLVCEKLRDRHQRH 214
Query: 235 RQTDLSITISHAFEPQLAKR---THLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQ 291
++ D I + A PQLA R + +++++ K D + E K DG+R+QIH G
Sbjct: 215 KRQD--IEVGKAVRPQLAMRIGDVNAAWKKLHGK---DVVAECKFDGDRIQIH--KNGTD 267
Query: 292 IKYLSRRGVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVK 351
I Y SR +D S + +S + + V CILDGEM+ +DT + FG +
Sbjct: 268 IHYFSRNFLDHS------EYAHAMSDLIVQNILVDKCILDGEMLVWDTSLNRFAEFGSNQ 321
Query: 352 SSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSV 411
A A +S+K + R + L K++ P++ +
Sbjct: 322 EIAK-------AAREGLDSHK---------------------QERHELLKKVVKPLKGRL 353
Query: 412 EIIQYMKAIN----------------AEAIKDSLEQAISMGSEGIVLKHLHSKYFVGSRN 455
E++ +N A ++ ++ + EGIVLK L SK+ G R+
Sbjct: 354 EVLVPEGGLNVHRPSGEPSWSIVVHAAADVERFFKETVENRDEGIVLKDLESKWEPGDRS 413
Query: 456 TDWIKIKPEYLEQFGENMDLLII------GREQGKKDSFFCGLSISDPNEVAEKP-RFIS 508
W+K+KPEY+ + G ++D+LII GR G+ F ++++D E P RF+S
Sbjct: 414 GKWMKLKPEYI-RAGADLDVLIIGGYYGSGRRGGEVAQFL--VALADRAEANVYPRRFMS 470
Query: 509 FCTIANGLSNEEFKDIERKT---WGKWHIFSEDPPS-PNLLGFGTKVPYEWI-HPEDSVV 563
FC + GLS++E + K + K + PPS + + P WI PE S++
Sbjct: 471 FCRVGTGLSDDELNTVVSKLKPYFRKNEHPKKAPPSFYQVTNHSKERPDVWIDSPEKSII 530
Query: 564 LEVKARAIDTKESEKRKYRSGCTLHFGYCKQIRYDKDWKTVASFSEFEDMKDARN-FYNK 622
L + + D + + + +L F ++RYDK W F ++ ++ N K
Sbjct: 531 LSITS---DIRTIRSEVFVAPYSLRFPRIDKVRYDKPWHECLDVQAFVELVNSSNGTTQK 587
Query: 623 RKSHQVTDGKKRASKRAKIGIVNSSEPTALVAPVSNTFSNCRFRVISDYFDSTKRRRISQ 682
+K + T + +K +K G + V+ V + F I D+ + R S
Sbjct: 588 QKESESTQDNPKVNKSSKRGEKKN------VSLVPSQFIQTDVSDIKDFVNVP--RSHSL 639
Query: 683 EDLCSVILEHGGEIVYTSDENNLPQDNLYIIGEKLTRECKILLNAKNLIIRPSWIFSCIE 742
E +++E+GG+ NL + I + + + +I SW+ C
Sbjct: 640 ETFHKMVVENGGKF-----SMNLNNSVTHCIAAESSGIKYQAAKRQRDVIHFSWVLDCCS 694
Query: 743 EGYKTPFTE------SDIFRGELESSMD--CSQFYTDFNTASLNHLLETANR 786
P +D R +L+ +D +Y D + L +L A +
Sbjct: 695 RNKMLPLLPKYFLHLTDASRTKLQDDIDEFSDSYYWDLDLEGLKQVLSNAKQ 746
>7292907 [L] KOG0966 ATP-dependent DNA ligase IV
Length = 918
Score = 171 bits (434), Expect = 4e-42
Identities = 192/729 (26%), Positives = 313/729 (42%), Gaps = 105/729 (14%)
Query: 62 YPALRLIVPFRD--RRIYNVKENTLIKALCRYLRLPKSSETENRLLRWKQRAARGVKLSD 119
Y LRL++P D R Y ++ L + R L+LP S RL R D
Sbjct: 67 YSVLRLLLPGADTGRDTYGLQITALGRLYIRVLQLPTDSSDAIRLQHRNGNMYRDY--GD 124
Query: 120 FCVEEIRKRQKDYEGANRITIDELNGYLDEVSQEGNGKRMGYMALTDSRAFNYCLNHMTF 179
++ R + + + + E++ LD ++ E + + +A +
Sbjct: 125 VVYSVLKPRC--FNPPSNLRLKEIHQMLDTIANEDTEVKQQQLIRFTEQA--------SP 174
Query: 180 MEMKFFFDIILKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERLRQTDL 239
E K+ ++LK+ L E HP A D SDL + L + R TDL
Sbjct: 175 EEQKWLIRLLLKSLGLGIGEQKIFGVLHPKAQDIYQRCSDLGHVCNLLAD-----RTTDL 229
Query: 240 SITIS-------------------HAFEPQLAKRTHLSYERVASKLQHDFI-IEEKMDGE 279
+ S H P L +R + + +Q D + +E KMDGE
Sbjct: 230 DASSSKDSKAAVKFVNLNSVIRPFHQIRPMLCERFPGDIQEL---MQSDVLYLETKMDGE 286
Query: 280 RLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLK--LHFNVKDCILDGEMITY 337
R Q+H I+ G + Y+SR GVD++ +G + G ++P L+ L ++ ILDGEM+ +
Sbjct: 287 RFQLH-IDRG-RFMYISRNGVDYTRNFGHSYDHGTLTPKLRGLLPLGLESIILDGEMMVW 344
Query: 338 DTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRK 397
DT K L F + N +++ + P S++P FV +DL+Y NG+SL + +R
Sbjct: 345 DTNK---LRF---REKGEN---TDVKSLKPEGSWQPCFVVYDLLYFNGQSLLDHTYIQRA 395
Query: 398 DYLTKILTPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGIVLKHLHSKYFVGSR-NT 456
L K++ +++++ K + + + +QA+ +EGIVLK S+Y G R
Sbjct: 396 YKLQKLIVEQSGVLQLMRARKIGSVQEFNELFQQALDSHAEGIVLKKQGSRYQPGVRLGG 455
Query: 457 DWIKIKPEYLEQFGENMDLLIIGREQGKK----DSFFCGLSISDPNEVAEKPRFISFCTI 512
W K K +Y++ D+LIIG +K DSF G+ P + +P S +
Sbjct: 456 GWYKDKADYIKGLITEFDVLIIGAFYNRKRTFVDSFLLGVLQPAPPGSSNRPEVFSIGVV 515
Query: 513 AN-----GLSNEEFKDIERKTWGKWHIFSEDPPSPNLLGFGTK----VPYEWIHPEDSVV 563
AN G+ N K WH +PP P + K P WI P++SV+
Sbjct: 516 ANNTKQRGVLNHTLKP-------HWHDVVNEPP-PLWFHYKPKERSGCPDLWIEPQNSVI 567
Query: 564 LEVKARAIDTKESEKRKYRSGCTLHFGYCKQIRYDKDWKTVASFSEFEDMKD---ARNFY 620
L+VKA + + + + +LHF + R DK W + EF D+ A
Sbjct: 568 LQVKAADL----APNGAFFTRKSLHFPRTEMKRDDKTWSECMTLKEFNDLCGGPLAIKKL 623
Query: 621 NKR--KSHQVTDGKKR----ASKRAKIG--IVNSSEPTALVAPVSNTFSNCRFRVISDYF 672
NKR + VT +K+ S+R+++G + + A S F F ++S
Sbjct: 624 NKRQLRLEDVTTKRKQMRMTPSERSRLGLAVYEKRYDASTSASTSKLFDGLSFCILSG-- 681
Query: 673 DSTKRRRISQEDLCSVILEHGGEIVYTSDENNLPQDN--LYIIGEKLTRECKILLNAKNL 730
R S+ L + +++GG IV EN LP D I G++ +++L
Sbjct: 682 ---SAGRHSKHQLQELAVKNGGCIV----ENPLPNDPKCFCIAGDETFLVKRLILQQPRT 734
Query: 731 --IIRPSWI 737
I+R W+
Sbjct: 735 CDIVRMEWL 743
>Hs4557719 [L] KOG0967 ATP-dependent DNA ligase I
Length = 919
Score = 116 bits (290), Expect = 2e-25
Identities = 101/356 (28%), Positives = 169/356 (47%), Gaps = 25/356 (7%)
Query: 217 VSDLD-VLSQRLYNPNERLRQTDLSITISHAFEPQLAKRTHLSYERVASKLQHDFIIEEK 275
V DLD ++ L + ERL + ++ +P LA T E + + F E K
Sbjct: 510 VPDLDRIIPVLLEHGLERLPE-HCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYK 568
Query: 276 MDGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMI 335
DG+R QIH + GE +K SR D + Y + S P +KL +V ILD E +
Sbjct: 569 YDGQRAQIHALEGGE-VKIFSRNQEDNTGKYPDIISR---IPKIKLP-SVTSFILDTEAV 623
Query: 336 TYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALER 395
+D EK + PF ++ + ++ + + + AFDL+YLNG+SL L R
Sbjct: 624 AWDREKKQIQPFQVLTTRKRKEVDASEIQV------QVCLYAFDLIYLNGESLVREPLSR 677
Query: 396 RKDYLTKILTPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGIVLKHL--HSKYFVGS 453
R+ L + E + + E I + LEQ++ EG+++K L + Y +
Sbjct: 678 RRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAK 737
Query: 454 RNTDWIKIKPEYLEQFGENMDLLIIGR--EQGKKDSFFCGLSISDPNEVAEKPRFISFCT 511
R+ +W+K+K +YL+ G+ +DL++IG +GK+ + G ++ +E +E+ + I C
Sbjct: 738 RSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAI--CK 795
Query: 512 IANGLSNEEFKDIERKTWGKWHIFSEDPPSPNLLGFGTKVPYEWIHPEDSVVLEVK 567
+ G S+EE ++ + P P + G +P W+ P S V EVK
Sbjct: 796 LGTGFSDEELEEHHQSL----KALVLPSPRPYVRIDGAVIPDHWLDP--SAVWEVK 845
>YDL164c [L] KOG0967 ATP-dependent DNA ligase I
Length = 755
Score = 108 bits (269), Expect = 5e-23
Identities = 91/372 (24%), Positives = 166/372 (44%), Gaps = 23/372 (6%)
Query: 248 EPQLAKRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYLYG 307
+P LAK T E + F E K DGER Q+H +N G Y SR G + + Y
Sbjct: 392 KPMLAKPTKAINEVLDRFQGETFTSEYKYDGERAQVHLLNDGTMRIY-SRNGENMTERYP 450
Query: 308 ENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAP 367
E + I+ ++ K+ ILD E + +D ++ +LPF ++ + ++ +
Sbjct: 451 EIN----ITDFIQDLDTTKNLILDCEAVAWDKDQGKILPFQVLSTRKRKDVELNDVKV-- 504
Query: 368 TESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAEAIKD 427
K AFD++ N + L N +L+ R++YLTK+ V + + N + ++
Sbjct: 505 ----KVCLFAFDILCYNDERLINKSLKERREYLTKVTKVVPGEFQYATQITTNNLDELQK 560
Query: 428 SLEQAISMGSEGIVLKHL---HSKYFVGSRNTDWIKIKPEYLEQFGENMDLLIIGR--EQ 482
L+++++ EG+++K L S Y R+ +W+K+K +YLE G+++DL ++G +
Sbjct: 561 FLDESVNHSCEGLMVKMLEGPESHYEPSKRSRNWLKLKKDYLEGVGDSLDLCVLGAYYGR 620
Query: 483 GKKDSFFCGLSISDPNEVAEKPRFISFCTIANGLSNEEFKDIERKTWGKWHIFSEDPPSP 542
GK+ + G + N+ + F + C I G S+E + + + D P
Sbjct: 621 GKRTGTYGGFLLGCYNQ--DTGEFETCCKIGTGFSDEMLQLLHDRLTPT----IIDGPKA 674
Query: 543 NLLGFGTKVPYEWIHPEDSV-VLEVKARAIDTKESEKRKYRSGCTLHFGYCKQIRYDKDW 601
+ + P W P VL ++ + G +L F +IR DK
Sbjct: 675 TFVFDSSAEPDVWFEPTTLFEVLTADLSLSPIYKAGSATFDKGVSLRFPRFLRIREDKGV 734
Query: 602 KTVASFSEFEDM 613
+ S + ++
Sbjct: 735 EDATSSDQIVEL 746
>ECU02g1220 [L] KOG0967 ATP-dependent DNA ligase I
Length = 589
Score = 102 bits (255), Expect = 2e-21
Identities = 107/445 (24%), Positives = 190/445 (42%), Gaps = 41/445 (9%)
Query: 180 MEMKFFFDIILKTRVLSGLENMFLTAWHPDATDYLSVVSDLDVLSQRLYNPNERLRQTDL 239
+E + + LKT VL L N+F + + D+ L+ L T
Sbjct: 162 IEGRLKIGLALKT-VLISLANVFSDDKIDEIKAAFNRQPDIGRLADCLLEHGVEGLSTKF 220
Query: 240 SITISHAFEPQLA---KRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLS 296
+T +P L+ K +++RV +K F E K DGER+QIH + ++ S
Sbjct: 221 QVTPGIPLKPMLSNPSKDLTSAFKRVENK---SFTCEYKYDGERVQIH--RFDSSVETFS 275
Query: 297 RRGVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMN 356
R + Y + +S +D I+DGE++ Y+ ++ +LPF ++ +
Sbjct: 276 RNSEKTTEKYPDLMGLYDVSD--------RDFIVDGEIVAYNQKERRILPFQVLTTRKRK 327
Query: 357 QIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQY 416
+++S E + +FV FDL+Y +G+S + LE R+ L ++ ++
Sbjct: 328 RVESN-----KIEVHVCVFV-FDLIYFDGRSWIDEPLEERRRVLHSSFKEIDGKFHFAEF 381
Query: 417 MKAINAEAIKDSLEQAISMGSEGIVLKHLHSK--YFVGSRNTDWIKIKPEYLEQFGENMD 474
E + +++ EG+++K L S Y R+ WIKIK +YLE +++D
Sbjct: 382 KDCETPEEAETFFNKSVENNFEGMMIKTLGSDATYLPSQRSNKWIKIKKDYLESMSDSLD 441
Query: 475 LLIIGREQGK--KDSFFCGLSISDPNEVAEKPRFISFCTIANGLSNEEFKDIERKTWGKW 532
L+++G GK + F+ G + N+ E+ +F + C I G + + +
Sbjct: 442 LVVMGAYYGKGRRAGFYGGFLLGVYND--EEEKFEALCKIGTGFDDSILSKLHEQ----- 494
Query: 533 HIFSEDPPSPNLLGFGTKV-PYEWIHPEDSVVLEVKARAIDTK---ESEKRKYRSGCTLH 588
+ S +P + V P W+ E V EV+A I + K G +L
Sbjct: 495 -LSSSLCSAPKNYSYKESVKPDVWV--EAKYVWEVRAAGISLSPIYSAAWSKGEKGISLR 551
Query: 589 FGYCKQIRYDKDWKTVASFSEFEDM 613
F + R DKD + + S+ M
Sbjct: 552 FPRFIRERDDKDVREATTSSQAYQM 576
>At1g49250 [L] KOG0967 ATP-dependent DNA ligase I
Length = 657
Score = 100 bits (250), Expect = 8e-21
Identities = 102/406 (25%), Positives = 184/406 (45%), Gaps = 42/406 (10%)
Query: 240 SITISHAFEPQLAKRTHLSYERVASKLQHD-FIIEEKMDGERLQIHYINYGEQIKYLSRR 298
++T+ P LAK T + + K + F E K DGER QI+Y+ G ++ SR
Sbjct: 278 NLTLGVPVRPMLAKAT-TRVDLILEKFKDTVFTAEYKYDGERAQIYYMEDGT-VEIFSRH 335
Query: 299 GVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQI 358
+ G+ + LK VK ILD E++T++ EK+ +LP ++ +
Sbjct: 336 AERNT---GKYPDVALVLSRLKKP-TVKSFILDCEVVTFNREKEKILPLQSTRAHKNVNV 391
Query: 359 QSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMK 418
G+ AFD++YLNG+ L + L R++ K+ E + Q+
Sbjct: 392 SDIKVGVC--------VFAFDILYLNGQLLIHENLNIRRE---KLHDSFEEDLGYFQFAT 440
Query: 419 AINAEAI---KDSLEQAISMGSEGIVLKHLHSK--YFVGSRNTDWIKIKPEYLEQFGENM 473
A+ + I ++ L+ +I +G EG+++K L+S Y R+ +W+K+K +Y++ G+++
Sbjct: 441 ALTSNDIGELQEFLKASIDIGCEGLMIKSLYSNATYEPAKRSNNWLKLKKDYMDNIGDSV 500
Query: 474 DLLIIG--REQGKKDSFFCGLSISDPNEVAEKPRFISFCTIANGLSNEEFKDIERKTWG- 530
DL+ I +GK+ FF ++ + +K F S C I S+ E +D+
Sbjct: 501 DLVPIATFHGRGKRTGFFGAYLLACYD--VDKEEFQSICKIGTEFSDVELQDLSSSLCSK 558
Query: 531 -----KWHIFSEDPPSPNLLGFGTKVPYEW-IHPEDSVVLEVKARAIDTKESEKRKYRSG 584
K + ++ +P++ T+V W + D V V AI + +K G
Sbjct: 559 VIATPKQYYQVDNDLNPDVWLEPTEV---WEVKAADLTVSPVYREAIGIVDPDK-----G 610
Query: 585 CTLHFGYCKQIRYDKDWKTVASFSEFEDMKDARNFYNKRKSHQVTD 630
+L F +IR DK+ + + + +M A+ +V D
Sbjct: 611 ISLRFPRLVRIRKDKNPEEATTSDQIAEMYQAQKHNQPSNQGKVDD 656
>7291668 [L] KOG0967 ATP-dependent DNA ligase I
Length = 692
Score = 97.4 bits (241), Expect = 9e-20
Identities = 71/277 (25%), Positives = 131/277 (46%), Gaps = 20/277 (7%)
Query: 250 QLAKRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYLYGEN 309
Q K H +ER E K DGER QIH GE I SR + + Y +
Sbjct: 318 QPTKGVHEVFERFGGM---QITCEWKYDGERAQIHRNEKGE-ISIFSRNSENNTAKYPDL 373
Query: 310 SSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTE 369
+ + L +VK I+D E++ +D E+ +LPF ++ + + E +
Sbjct: 374 IARS----TALLKGDVKSYIIDSEIVAWDVERKQILPFQVLSTRKRKNVDIEEIKV---- 425
Query: 370 SYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAEAIKDSL 429
+ FDL+Y+NG +L L R+ L + VE + + + + ++ L
Sbjct: 426 --QVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTNDIDEVQQFL 483
Query: 430 EQAISMGSEGIVLKHLHSK--YFVGSRNTDWIKIKPEYLEQFGENMDLLIIG--REQGKK 485
E++I EG+++K L + Y + R+ +W+K+K +YL G+++DL++IG + +G++
Sbjct: 484 EESIKGNCEGLMVKTLDEEATYEIAKRSRNWLKLKKDYLSNVGDSLDLVVIGGYKGKGRR 543
Query: 486 DSFFCGLSISDPNEVAEKPRFISFCTIANGLSNEEFK 522
+ G ++ + E + S C I G ++E+ +
Sbjct: 544 TGTYGGFLLACYD--TENEEYQSICKIGTGFTDEDLQ 578
>Hs7710126 [L] KOG4437 ATP-dependent DNA ligase III
Length = 922
Score = 96.3 bits (238), Expect = 2e-19
Identities = 132/601 (21%), Positives = 239/601 (38%), Gaps = 87/601 (14%)
Query: 44 EIITNFIKLWRSTVGNY--IYPALRLIVPFRDRRIYNVKENTLIKALCRYLRLPKSSETE 101
+II +F++ + G + +Y ++L++P + +YN+ + ++K R
Sbjct: 197 QIIQDFLRKGSAGDGFHGDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDD--- 253
Query: 102 NRLLRWKQRAARGVKLSDFCVEEIR---KRQKDYEGANR--ITIDELNGYLDEVSQEGNG 156
AR ++ D E IR ++ K + A + +TI E++ +L +S+
Sbjct: 254 ---------MARDLEQGDVS-ETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSKLTKE 303
Query: 157 KRMGYMALTDSRAFNYCLNHMTFMEMKFFFDIILKTRVLSGLENMFLTAWHPDATDYLSV 216
+A + T ++K +I ++ L A P+A +
Sbjct: 304 DEQ-------QQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKA 356
Query: 217 VSDL-DVLSQRLYNPNE------RLRQTDLSITISHAFEPQLAKRTHLSYERVASKLQHD 269
+L DV+ + L+N E + R + ++ +P LA+ S E K +
Sbjct: 357 SRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTPVQPMLAEACK-SVEYAMKKCPNG 415
Query: 270 FIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLKLHFNV---- 325
E K DGER+Q+H G+ Y SR S P+ P HF
Sbjct: 416 MFSEIKYDGERVQVH--KNGDHFSYFSR-------------SLKPVLPHKVAHFKDYIPQ 460
Query: 326 -----KDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDL 380
ILD E++ D + LPFG + Q A + LFV FD
Sbjct: 461 AFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQD--ANVC-------LFV-FDC 510
Query: 381 VYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGI 440
+Y N SL + L R+ +L + + + + + A + D + + I G EG+
Sbjct: 511 IYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGL 570
Query: 441 VLKHLHSKYFVGSRNTDWIKIKPEYLEQ--FGENMDLLIIGR--EQGKKDSFFCGLSISD 496
VLK + Y G R+ W+K+K +YL + + DL+++G QG K +
Sbjct: 571 VLKDVKGTYEPGKRH--WLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGC 628
Query: 497 PNEVAEKPRFISFCTIANGLSNEEFKDIER-KTWGKWHIFSEDPPS-PNLLGFGTKVPYE 554
+ ++K +CT+ + + R + S+DP P+ L +
Sbjct: 629 YDPGSQK-----WCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPD 683
Query: 555 WI--HPEDSVVLEVKARAIDTKESEKRKYRSGCTLHFGYCKQIRYDKDWKTVASFSEFED 612
+I P+ + V E+ E+ G ++ F C +IR DKDWK+ + + ++
Sbjct: 684 FIVPDPKKAAVWEITGAEFSKSEAHT---ADGISIRFPRCTRIRDDKDWKSATNLPQLKE 740
Query: 613 M 613
+
Sbjct: 741 L 741
>Hs4504995 [L] KOG4437 ATP-dependent DNA ligase III
Length = 862
Score = 96.3 bits (238), Expect = 2e-19
Identities = 132/601 (21%), Positives = 239/601 (38%), Gaps = 87/601 (14%)
Query: 44 EIITNFIKLWRSTVGNY--IYPALRLIVPFRDRRIYNVKENTLIKALCRYLRLPKSSETE 101
+II +F++ + G + +Y ++L++P + +YN+ + ++K R
Sbjct: 197 QIIQDFLRKGSAGDGFHGDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDD--- 253
Query: 102 NRLLRWKQRAARGVKLSDFCVEEIR---KRQKDYEGANR--ITIDELNGYLDEVSQEGNG 156
AR ++ D E IR ++ K + A + +TI E++ +L +S+
Sbjct: 254 ---------MARDLEQGDVS-ETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSKLTKE 303
Query: 157 KRMGYMALTDSRAFNYCLNHMTFMEMKFFFDIILKTRVLSGLENMFLTAWHPDATDYLSV 216
+A + T ++K +I ++ L A P+A +
Sbjct: 304 DEQ-------QQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKA 356
Query: 217 VSDL-DVLSQRLYNPNE------RLRQTDLSITISHAFEPQLAKRTHLSYERVASKLQHD 269
+L DV+ + L+N E + R + ++ +P LA+ S E K +
Sbjct: 357 SRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTPVQPMLAEACK-SVEYAMKKCPNG 415
Query: 270 FIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLKLHFNV---- 325
E K DGER+Q+H G+ Y SR S P+ P HF
Sbjct: 416 MFSEIKYDGERVQVH--KNGDHFSYFSR-------------SLKPVLPHKVAHFKDYIPQ 460
Query: 326 -----KDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDL 380
ILD E++ D + LPFG + Q A + LFV FD
Sbjct: 461 AFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQD--ANVC-------LFV-FDC 510
Query: 381 VYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGI 440
+Y N SL + L R+ +L + + + + + A + D + + I G EG+
Sbjct: 511 IYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGL 570
Query: 441 VLKHLHSKYFVGSRNTDWIKIKPEYLEQ--FGENMDLLIIGR--EQGKKDSFFCGLSISD 496
VLK + Y G R+ W+K+K +YL + + DL+++G QG K +
Sbjct: 571 VLKDVKGTYEPGKRH--WLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGC 628
Query: 497 PNEVAEKPRFISFCTIANGLSNEEFKDIER-KTWGKWHIFSEDPPS-PNLLGFGTKVPYE 554
+ ++K +CT+ + + R + S+DP P+ L +
Sbjct: 629 YDPGSQK-----WCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPD 683
Query: 555 WI--HPEDSVVLEVKARAIDTKESEKRKYRSGCTLHFGYCKQIRYDKDWKTVASFSEFED 612
+I P+ + V E+ E+ G ++ F C +IR DKDWK+ + + ++
Sbjct: 684 FIVPDPKKAAVWEITGAEFSKSEAHT---ADGISIRFPRCTRIRDDKDWKSATNLPQLKE 740
Query: 613 M 613
+
Sbjct: 741 L 741
>CE05328 [L] KOG0967 ATP-dependent DNA ligase I
Length = 847
Score = 84.7 bits (208), Expect = 6e-16
Identities = 102/432 (23%), Positives = 183/432 (41%), Gaps = 52/432 (12%)
Query: 248 EPQLAKRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIKYLSRRGVDFSYLYG 307
+P LA T E + E K DGER QIH G QI SR + + Y
Sbjct: 336 KPMLAHPTKGIDEIMRRFRNQTMTCEWKYDGERGQIHKREDG-QIFIYSRNQENNTTKYP 394
Query: 308 ENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAP 367
+ S + V I+D E++ D E ++LPF ++ + +
Sbjct: 395 DIIEK----ISSCIGDGVTSFIVDAEVVAID-EAGLILPFQVLSTRKRKNATDD------ 443
Query: 368 TESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMKAINAEAIKD 427
K + FDL+Y NG+ L L +R++ L ++ S + + + I
Sbjct: 444 -NGVKVVVFLFDLLYFNGEPLVRKPLRKRRELLRTNFKKIDGSFYFATSVDTNDTDEINS 502
Query: 428 SLEQAISMGSEGIVLKHLHSK--YFVGSRNTDWIKIKPEYLEQFGENMDLLIIGREQ--G 483
++A+ EG+++K L ++ Y + R+ W+K+K +Y++ G+ +DL+++G G
Sbjct: 503 FFDEAVQNKCEGLMIKTLDTEATYEISRRSHSWLKMKKDYVDGVGDTLDLVVMGAYSGVG 562
Query: 484 KKDSFFCGLSISDPNEVAEKPRFISFCTIANGLSN----EEFKDIERKTWGKWHIFSEDP 539
K+ + G + N E+ + S C I G ++ E++K ++ K K
Sbjct: 563 KRTGVYGGYLLGCYNPTTEE--YESVCKIGTGFTDEDLAEQYKILQDKKIDK-------- 612
Query: 540 PSPNLLGFGTKVPYEWIHPED--SVVLEVKARAIDTKESEKRKYRSGCT-------LHFG 590
SP+ F + P+D S L + + D S + K SG T L F
Sbjct: 613 -SPSYYQFD-----HTLKPDDTFSPYLVFEVKCADITISPRHKAASGLTDDGKGISLRFP 666
Query: 591 YCKQIRYDKDWKTVASFSEFEDM-KDARNFYNKR--KSHQVTDG---KKRASKRAKIGIV 644
+IR DK+ S + +M K+ F N++ K+ V + +++ + ++ +
Sbjct: 667 RFLRIRDDKNSDDATSSEQVLEMYKNQEAFANQKIEKADAVDEDDEFEEKEDEEEELNMT 726
Query: 645 NSSEPTALVAPV 656
N SE ++ PV
Sbjct: 727 NVSEGSSKENPV 738
>7299616 [L] KOG4437 ATP-dependent DNA ligase III
Length = 734
Score = 79.3 bits (194), Expect = 2e-14
Identities = 100/441 (22%), Positives = 180/441 (40%), Gaps = 66/441 (14%)
Query: 65 LRLIVPFRDRRIYNVKENTLIKALCRYLRLPKSSETENRLLRWKQRAARGVKLSDFCVEE 124
++ ++P ++R+YN++ LIK R +++ + L +Q F +
Sbjct: 57 VQFLIPAANQRVYNLQNKALIKLFSRIF----NADQQQMHLDLEQGDVSETLRKHFAASK 112
Query: 125 IRKRQKDYEGANRITIDELNGYLDE-VSQEGNGKRMGYMALTDSRAFNYCLNHMTFMEMK 183
K QK +++ + E+ L V + ++ + S+A T ++++
Sbjct: 113 KLKPQKQ----SKLYLQEVEEMLLHLVERTKEDEQTDLLQKLCSKA--------TDLDLR 160
Query: 184 FFFDIILKTRVLSGLENMFLTAWHPDA-------TDYLSVVSDLDVLSQRLY--NPNERL 234
F ++ ++ L A+ PDA D +++V + Y +P ++
Sbjct: 161 TFIRLVKHDLRINARARHILDAFGPDAYPAYQSSRDLVAIVEQFATKENKNYASSPVKKT 220
Query: 235 RQTDLS-ITISHAFEPQLAKRTHLSYERVASKLQHDFIIEEKMDGERLQIHYINYGEQIK 293
++T S I + P LA S E K E K DGER+QIH G K
Sbjct: 221 KKTSSSAIQVMTPISPMLASPCK-SVEDAFKKSPTGLYSEIKYDGERVQIH--KQGNDFK 277
Query: 294 YLSRR---GVDFS------YLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIV 344
+ SR VD Y+ G + ILD E+I DT+ +
Sbjct: 278 FFSRNLKPVVDHKIRALKKYIPQAFPGGG-------------EMILDSEIILVDTDTGAL 324
Query: 345 LPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKIL 404
LPFG + + + A + LFV FD + +G+ LT L +R++ L + +
Sbjct: 325 LPFGSLGAHKKQTFAN--AAVC-------LFV-FDCILYDGEDLTQLPFRKRREILEQNI 374
Query: 405 TPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGIVLKHLHSKYFVGSRNTDWIKIKPE 464
P++ V++ + + + + EG+VLK S Y G RN W+K+K +
Sbjct: 375 QPIKSHVQLSESEFLKTTRELAAMTARVLHANLEGVVLKSPTSTYQPGKRN--WLKVKKD 432
Query: 465 YL--EQFGENMDLLIIGREQG 483
YL + + DL+++G G
Sbjct: 433 YLFDGKMADTADLVVLGAWYG 453
>SPBC713.06 [L] KOG0967 ATP-dependent DNA ligase I
Length = 774
Score = 77.4 bits (189), Expect = 9e-14
Identities = 90/411 (21%), Positives = 174/411 (41%), Gaps = 32/411 (7%)
Query: 217 VSDLDVLSQRLYNPNERLRQTDLSITISHAFEPQLAKRTHLSYERVASKLQHDFIIEEKM 276
V D ++L L + ++SI +P L T + H+F E K
Sbjct: 375 VPDYNILVATLLREGIENLKDNMSIRPGIPVKPMLGSITKNLQHMLERLTDHNFSCEFKY 434
Query: 277 DGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMIT 336
DG+R QIH G IK SR + + + + ++ F I++GE++
Sbjct: 435 DGQRAQIHCDRLGN-IKIFSRHLEEITGRFPDVIEVAQLALKHSCDF-----IIEGELVA 488
Query: 337 YDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERR 396
D +L F + + ++ +A +FV FD+++ +GKS + L R
Sbjct: 489 IDKSNGQILDFQKLSTRERKKVT-----VADITIDVCVFV-FDIMFCDGKSCLQMPLIER 542
Query: 397 KDYLTKILTPVERSVEIIQYMKAINAEAIKDSLEQAISMGSEGIVLKHLH-------SKY 449
+ + + + + ++ ++I++ AI+ EG+++K L+ S Y
Sbjct: 543 RRMFFEHFNLIPNRFQFVSSLETNEEQSIQEFFSLAITNKCEGLMVKVLNGTNSKFPSTY 602
Query: 450 FVGSRNTDWIKIKPEYLEQFGENMDLLIIGR--EQGKKDSFFCGLSISDPNEVAEKPRFI 507
R WIK+K +Y ++F E++DL+ IG G+K +F + ++ N + +
Sbjct: 603 EPDKRGEGWIKVKQDYDDEF-ESLDLVPIGAWYGNGRKAGWFSPILLAVYN--PDTGAYE 659
Query: 508 SFCTIANGLSNEEFKDIERKTWGKWHIFSEDPPSPNLLGFGTKVPYEWIHPEDSVVLEVK 567
+ C +G S++ +K++ +K + S P N G P + P++ V E+K
Sbjct: 660 AVCKCMSGFSDQFYKELTQK-YSLESGNSSLKPIYNFCETGKVTPQIYFAPQE--VWEIK 716
Query: 568 ARAIDTKESEKR-----KYRSGCTLHFGYCKQIRYDKDWKTVASFSEFEDM 613
I + + K + G ++ F ++R DK + ++ S DM
Sbjct: 717 GAQITSSPAYKAALGLIQDDRGLSIRFPRFIRVRSDKGPEDASTNSILADM 767
>CE00757 [L] KOG0966 ATP-dependent DNA ligase IV
Length = 729
Score = 77.4 bits (189), Expect = 9e-14
Identities = 92/395 (23%), Positives = 167/395 (41%), Gaps = 36/395 (9%)
Query: 108 KQRAARGVKLSDFCVEEIRKRQKDYEGANRITIDELNGYLDEVSQE--GNGKRMGYMALT 165
K + +L++ EE R + + +T+ ELN LD ++ +G + M
Sbjct: 92 KDASTAARQLAEKISEEYRTENDE---STVVTVSELNEILDFLAAGPMDDGNKRDKM--- 145
Query: 166 DSRAFNYCLNHMTFMEMKFFFDIILKT--RVLSGLENMFLTAWHPDATDYLSVVSDLDVL 223
S+ C E+++ F++ILK L N L P A DL +
Sbjct: 146 -SKLVKRCSED----ELEWIFNVILKNVESALGAPSNRILDWISPSACAIWDQTHDLKAV 200
Query: 224 SQRLYNPNERLRQT-----DLSITISHAFEPQLAKRTHLS--YERVASKLQHDFIIEEKM 276
+ N+ + D + + P L ++ Y + F ++ K
Sbjct: 201 LKGKLVENKGTNELGETNDDDDEHLFKIWTPMLLQKQKRGDWYANIEKFGGQKFFLQTKF 260
Query: 277 DGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSS-GPISPSLKLHFNVKDC---ILDG 332
DGE + +H G + ++ +R DFS YG++S + G +S + FN K+C I +
Sbjct: 261 DGENVLLH--KKGNEYRWFTRNNNDFSKEYGDSSMAIGKLSSRIHSFFN-KECESAIFNC 317
Query: 333 EMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLA 392
E++ +D + + +++ Q+ S + P ++ + V FDL+YLNGK
Sbjct: 318 ELMLWDKKTKKLCRHNDASTTSDAQVLS-FRHVKPDDNQQLTVVLFDLLYLNGKPFFGAP 376
Query: 393 LERRKDYLTKILTPVER--SVEIIQYMKAINAEAIKDSLEQAISMGSEGIVLKHLHSKYF 450
L +R + L ER ++ + ++ + E I+ E A++ EGIV+K S Y
Sbjct: 377 LHQRLEMLKIAPLKKEREDTIFVAKHEEGSKKEDIQQFFEIAMANNEEGIVVKRTDSVYV 436
Query: 451 VGSRNTD--WIKIKPEYLEQFGENMDLLIIGREQG 483
G R+ W K+KP + ++DL ++ G
Sbjct: 437 KGQRSASNGWFKLKPSASKDC--DLDLALVAVHPG 469
>At1g66730_2 [L] KOG0967 ATP-dependent DNA ligase I
Length = 684
Score = 70.9 bits (172), Expect = 9e-12
Identities = 82/341 (24%), Positives = 145/341 (42%), Gaps = 43/341 (12%)
Query: 215 SVVSDLDVLSQRLYNPNERLRQTDLSITISHAFEPQLAKRTHLSYERVASKLQHDFIIEE 274
+++ LDV+ L + + + LS+ +P LAK E + F E
Sbjct: 246 NILPSLDVVVPSLMDKDIEFSTSTLSMVPGIPIKPMLAKIAKGVQEFFNLSQEKAFTCEY 305
Query: 275 KMDGERLQIHYINYGEQIKYLSRRGVDFSYLYGENSSSGPISPSLKLHFN---VKDCILD 331
K DG+R QIH + G + SR G E +S P + F+ + +LD
Sbjct: 306 KYDGQRAQIHKLLDGT-VCIFSRNG-------DETTSRFPDLVDVIKQFSCPAAETFMLD 357
Query: 332 GEMITYDTEKDIVLPFGLVKSSAMNQIQSELAGIAPTESYKP---LFVAFDLVYLNGKSL 388
E++ D L + + + + TES K +FV FD++++NG+ L
Sbjct: 358 AEVVATDRINGNKL---MSFQELSTRERGSKDALITTESIKVEVCVFV-FDIMFVNGEQL 413
Query: 389 TNLALERRKDYLTKILTPVERSVEIIQYMKAINAEA-----------------IKDSLEQ 431
L L R+ L ++ E ++Y K I A I LE+
Sbjct: 414 LALPLRERRRRLKEVFP--ETRPGYLEYAKEITVSATVGAEEASLNNHDTLSRINAFLEE 471
Query: 432 AISMGSEGIVLKHL--HSKYFVGSRNTDWIKIKPEYLEQFGENMDLLIIGR--EQGKKDS 487
A EGI++K L ++ Y R+ W+K+K +Y++ G+ +DL+ IG G+K
Sbjct: 472 AFQSSCEGIMVKSLDVNAGYCPTKRSDSWLKVKRDYVDGLGDTLDLVPIGAWYGNGRKAG 531
Query: 488 FFCGLSISDPNEVAEKPRFISFCTIANGLSNEEFKDIERKT 528
++ ++ N E+ F S C + +G S+ + ++ + +
Sbjct: 532 WYSPFLMACFNPETEE--FQSVCRVMSGFSDAFYIEVMKSS 570
>At1g08130 [L] KOG0967 ATP-dependent DNA ligase I
Length = 794
Score = 55.5 bits (132), Expect = 4e-07
Identities = 53/201 (26%), Positives = 91/201 (44%), Gaps = 19/201 (9%)
Query: 240 SITISHAFEPQLAKRTHLSYERVASKLQHD-FIIEEKMDGERLQIHYINYGEQIKYLSRR 298
+ T+ P LAK T + +K Q F E K DGER QIH++ G + SR
Sbjct: 409 NFTLGVPIGPMLAKPTK-GVAEILNKFQDIVFTCEYKYDGERAQIHFMEDGT-FEIYSRN 466
Query: 299 GVDFSYLYGENSSSGPISPSLKLHFNVKDCILDGEMITYDTEKDIVLPFGLVKSSAMNQI 358
+ Y + + ++ S +VK ILD E++ +D EK +LPF ++ + A +
Sbjct: 467 AERNTGKYPDVA----LALSRLKKPSVKSFILDCEVVAFDREKKKILPFQILSTRARKNV 522
Query: 359 QSELAGIAPTESYKPLFVAFDLVYLNGKSLTNLALERRKDYLTKILTPVERSVEIIQYMK 418
+ AFD++YLNG+ L L+ R++ K+ E Q+
Sbjct: 523 NVNDIKVG------VCIFAFDMLYLNGQQLIQENLKIRRE---KLYESFEEDPGYFQFAT 573
Query: 419 AINA---EAIKDSLEQAISMG 436
A+ + + I+ L+ ++ +G
Sbjct: 574 AVTSNDIDEIQKFLDASVDVG 594
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.319 0.137 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,845,714
Number of Sequences: 60738
Number of extensions: 2496984
Number of successful extensions: 6270
Number of sequences better than 1.0e-05: 18
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 6192
Number of HSP's gapped (non-prelim): 22
length of query: 907
length of database: 30,389,216
effective HSP length: 116
effective length of query: 791
effective length of database: 23,343,608
effective search space: 18464793928
effective search space used: 18464793928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)