ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0417 good R KOG0118 General function prediction only FOG: RRM domain
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0417 129351 132803 1151
(1151 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YML117w [R] KOG0118 FOG: RRM domain 405 e-112
SPAC2F7.11 [R] KOG0118 FOG: RRM domain 152 4e-36
YPL184c [R] KOG0118 FOG: RRM domain 150 1e-35
SPCC74.09 [R] KOG0118 FOG: RRM domain 103 2e-21
>YML117w [R] KOG0118 FOG: RRM domain
Length = 1134
Score = 405 bits (1041), Expect = e-112
Identities = 296/943 (31%), Positives = 433/943 (45%), Gaps = 207/943 (21%)
Query: 21 VGYEQQVYDVAGRNGGSNHHPPQY-IYYTHRXXXXXXXXXXXXXXXXXXXQTPFDPVYGI 79
VG + V NG + P Q+ YYT+ TPFD YG
Sbjct: 28 VGNPMMYHPVDFVNGAGQYGPSQHPAYYTN-------------SPLPNIPPTPFDTAYGA 74
Query: 80 TLLPSHLLVGSPFVNTPQTGGPMSAGTGAN------GVPVGSNNIMNLRNSSYKSFYPPA 133
+L PSHLL+GSPFV++P ++ +N PV ++N N ++S ++
Sbjct: 75 SLFPSHLLMGSPFVSSPNMQSGYNSARSSNLKRKAYSRPVSNHNGYNGNSNSNQN---NT 131
Query: 134 PKLRPAPSGRLRRARRKDNKPQQQREHSRDNNKVEAEYDVEXXXXXXXXXXXXXXXXXXX 193
PS R R ++ + NN +
Sbjct: 132 NNGMVTPSNYYRMGRNSFSRNNNSTRNVTHNNNKGCD--------------------TRN 171
Query: 194 XXXXXXXXXXXXXKTIDSELKIQ----FQYSILPKGNDTYRSRSLLFTNVNSELDIVEFL 249
I E+ +Q Y +LP G+D YR+RSLL NV+ +D+ +
Sbjct: 172 NSGRRTFARNNIFDDILPEMLLQRPFCINYKVLPTGDDAYRTRSLLIENVDHSIDLHSIV 231
Query: 250 QKVAKNYPIESIYLIKDEDTGDDIENLNTSXXXXXXXXXXXXXXXXXSKREDDKDKESAP 309
+ K+ +ES YLI+ K +D KD E
Sbjct: 232 KNFVKSNTLESAYLIEG------------------------------GKSDDSKDVE--- 258
Query: 310 ALTKQIAISPSSCSQQSYLLSFFTKESCLDFYNNLLQRYAEIKNAVKSDQLAMNFVKIQD 369
TK ++I L+SF TK CL+FYNN+LQR +E K +KS+ L + FV +
Sbjct: 259 --TKNLSI----------LISFLTKGDCLNFYNNILQRLSEFKTFLKSEALNLKFVCLNY 306
Query: 370 DEEWM--------------------------ANLKMNVISLGATRSLYVEFADDSVTSDT 403
D + + A+L N+ + ATRS+ +EF SD
Sbjct: 307 DPKCLPTFIESEALTENAEEADITNGSTMISASLHHNIANKDATRSIIIEFKSPVEKSDL 366
Query: 404 IWDTLPFLKNSG--KYXXXXXXXXXXXERRKNFGLHYCLLHFLSVTMALEVKELLETGDE 461
L FL S +Y F +Y +L FL+++MA+EV + L+ +
Sbjct: 367 FKKKLQFLDRSKNKRYILESIDLVNTDVPSNQFPENYAVLTFLNISMAIEVLDYLKKYSK 426
Query: 462 --AVSRVSFVTPA----NSADKEMRRRRSSAISLKQEASPQMFSTDXXXXXXXXN----- 510
+S+ +V+ A +SA + S + + P + + + N
Sbjct: 427 NLGISKCFYVSLAPLVVSSARSSVANIYEGKTSTHRLSVPSVTAGNNNDSNNNGNNNKSN 486
Query: 511 --------------VSLPLSEQVSTASTDISTPIYEEFDG--------NLTWSTLIVDVS 548
VS+ +S S S + EE D L + L ++
Sbjct: 487 MSGITTLNNNSSIGVSVYGHSNMSLTSLSSSVSLNEEIDMLATKLQGVELDGTYLEINYR 546
Query: 549 EYKEPIVNEFDHHLNSWSISKPTT------------------LYMHESGTTNFXXXXXXX 590
+Y+ P + E HL++ ISK T ++M++S +N
Sbjct: 547 DYQTPTIEEHSTHLSNVKISKTTENSRQFSQDIPSPLPLNEHMFMNDSNQSN-------- 598
Query: 591 XXXXXXXXXXXXVPQQMLLNEYPY-----IMEPLMPPQITQTIQNQYSKSIQ---AVNAG 642
+PQQ++ P + + ++P ITQ+++ ++ S + ++ +
Sbjct: 599 ---------GAIIPQQLIATPSPVSPNLQMNQRVLPNPITQSLEQNFNVSAKVASSMGSD 649
Query: 643 MEHRTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHKRICFVTFIETAAAVQFYANTTL 702
+ +RT+YIGNINPRSKAEDICNVVRGGILQ IK++ K+ICFVTFIE +AVQFYAN+ +
Sbjct: 650 IGNRTIYIGNINPRSKAEDICNVVRGGILQSIKYIPEKKICFVTFIEAPSAVQFYANSFI 709
Query: 703 EPIILHGNVLKVGWGQNPGPLPKNIALAVTVGASRNVYVSLPDKAFKDKFINDPQFKEYQ 762
+PI+LHGN+L+VGWG GPLPK I+LAVT+GASRNVYVSLP+ AFK+KFI+DPQ+K+
Sbjct: 710 DPIVLHGNMLRVGWGHYSGPLPKLISLAVTIGASRNVYVSLPEFAFKEKFIHDPQYKKLH 769
Query: 763 NRYKIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINFMNISSAIKLVEEYSD-------- 814
+P+ QL+ DF YG +EQ+N+ SD HCCWINFMNISSAI LVEE +
Sbjct: 770 ETLSLPDAEQLREDFSTYGDIEQINYLSDSHCCWINFMNISSAISLVEEMNKESTVQNES 829
Query: 815 ---TKDNLFHKKTEGRYVGLIIGYGKDRCGNINRNLVFNKNGK 854
T +K GRY GL+I YGKDRCGNIN+NL+ KN +
Sbjct: 830 GEVTLKRATEEKFGGRYKGLLINYGKDRCGNINKNLIAGKNSR 872
>SPAC2F7.11 [R] KOG0118 FOG: RRM domain
Length = 529
Score = 152 bits (383), Expect = 4e-36
Identities = 76/198 (38%), Positives = 113/198 (56%), Gaps = 30/198 (15%)
Query: 645 HRTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHKRICFVTFIETAAAVQFYANTTLEP 704
+RTVYIGNI+ + E+ICN VRGG+L +I+++ K ICFVTF++ +A +F+ + +
Sbjct: 322 NRTVYIGNIHADTTIEEICNAVRGGLLHNIRYLQEKHICFVTFVDPVSAFRFFEMSNIHG 381
Query: 705 IILHGNVLKVGWGQNPGPLPKNIALAVTVGASRNVYVSLPDKAFKDKFINDPQFKEYQNR 764
+++ LK+GWG++ GPLP NIALAV GASRN+Y+ D +
Sbjct: 382 LVIRNRRLKIGWGKHSGPLPSNIALAVAGGASRNIYIGNADDSL---------------- 425
Query: 765 YKIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINFMNISSAIKLVEEYSDTKDNLFHKKT 824
I +LK DF +G +E VNF + +C ++NF +++SAI ++ K
Sbjct: 426 ----TIERLKEDFEEFGEIEYVNFFREKNCAFVNFTSLASAINAIDRIKQKKG------- 474
Query: 825 EGRYVGLIIGYGKDRCGN 842
Y I YGKDRCGN
Sbjct: 475 ---YENYRISYGKDRCGN 489
Score = 83.2 bits (204), Expect = 2e-15
Identities = 54/212 (25%), Positives = 105/212 (49%), Gaps = 33/212 (15%)
Query: 646 RTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHKRICFVTFIETAAAVQFYANTTLEPI 705
+TVY+GN+ P + ++I + VR G ++ + K F++F++ + A F+ + L+ +
Sbjct: 115 KTVYVGNLPPNTPIDEILSCVRTGPIESAWILPEKNCAFISFLDPSHATAFFQDAALKRL 174
Query: 706 ILHGNVLKVGWGQNPGPLPKNIALAVTVGASRNVYV-SLPDKAFKDKFINDPQFKEYQNR 764
+ G +KVGWG+N + GA RNV++ +LP+ +D
Sbjct: 175 TIRGTEVKVGWGKNSASNSSVLLAVQQSGACRNVFLGNLPNGITED-------------- 220
Query: 765 YKIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINFMNISSAIKLVEEYSDTKDNLFHKKT 824
+++ D +G ++Q+ ++ + +++F+NI++AIK V+E L K +
Sbjct: 221 -------EIREDLEPFGPIDQIKIVTERNIAFVHFLNIAAAIKAVQELP-----LNPKWS 268
Query: 825 EGRYVGLIIGYGKDRCG-NINRNLVFNKNGKG 855
+ R I YG+DRC + + F+K G
Sbjct: 269 KRR-----IYYGRDRCAVGLKQPAYFSKGQVG 295
>YPL184c [R] KOG0118 FOG: RRM domain
Length = 612
Score = 150 bits (379), Expect = 1e-35
Identities = 89/220 (40%), Positives = 130/220 (58%), Gaps = 25/220 (11%)
Query: 628 IQNQYSKSIQAVNAG----MEHRTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHKRIC 683
+Q + + A +AG + +RTVY+G++ K E+ICN VRGG+LQ IK ++ + +C
Sbjct: 409 LQQSAAAAAIATSAGGPNNLGNRTVYLGSLPKDVKIEEICNAVRGGLLQSIKLLNDRYVC 468
Query: 684 FVTFIETAAAVQFYANTTLEPIILHGNVLKVGWGQNPGPLPKNIALAVTVGASRNVYVSL 743
FVTFI+ AA QFYA ++L + KVGWG++ GPLP +ALAV+ GASRNVYV
Sbjct: 469 FVTFIDPTAAAQFYAMSSLYGFTVQKKRCKVGWGKHSGPLPNALALAVSNGASRNVYVGN 528
Query: 744 PDKAFKDKFINDPQFKEYQNRYKIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINFMNIS 803
D F+ D E ++ + L+ F YG +EQ+NF + +CC+IN+ NIS
Sbjct: 529 ID------FVGDSLRDE-----RVFTESNLRHIFQQYGEVEQINFLPEKNCCFINYTNIS 577
Query: 804 SAIKLVEEYSDTKDNLFHKKTEGRYVGLIIGYGKDRCGNI 843
+AI +++ K N + K L I +GKDRCGN+
Sbjct: 578 NAILALDK---IKSNPYFK-------DLKINFGKDRCGNV 607
Score = 84.7 bits (208), Expect = 8e-16
Identities = 55/205 (26%), Positives = 99/205 (47%), Gaps = 24/205 (11%)
Query: 646 RTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHKRICFVTFIETAAAVQFYANTTLEPI 705
RTVY+GN+ P +++ + VR G+++ +K + K FV+FI+ +AA+ F+++ L+ +
Sbjct: 201 RTVYLGNVPPNLSVKELLDHVRSGVVEDVKIIPEKMCAFVSFIDESAALLFHSDAILKRL 260
Query: 706 ILHGNVLKVGWGQNPGPLPKNIALAVTVGASRNVYVSLPDKAFKDKFINDPQFKEYQNRY 765
+ +K+GWG+ P A T GA+RNVY+ ++ +++
Sbjct: 261 NIGDRDIKIGWGKPTRIDPIVAARISTDGATRNVYIGRMTIEGEESHLSE---------- 310
Query: 766 KIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINFMNISSAIKLVEEYSDTKDNLFHKKTE 825
QL+ D YG ++ + + +I+F +I +AIK+V +K+
Sbjct: 311 -----EQLRVDLEEYGEIDCIKIIKEKGIAFIHFASILNAIKVVTNLPIRNPYYQNKR-- 363
Query: 826 GRYVGLIIGYGKDRCGNINRNLVFN 850
I YGKDRC I + N
Sbjct: 364 -------IFYGKDRCAFITKTQQHN 381
>SPCC74.09 [R] KOG0118 FOG: RRM domain
Length = 654
Score = 103 bits (257), Expect = 2e-21
Identities = 57/165 (34%), Positives = 93/165 (55%), Gaps = 20/165 (12%)
Query: 645 HRTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHKRICFVTFIETAAAVQFYANTTLEP 704
+RTV++GN++ ++K +IC+++R G LQ ++ K ICFVTFI +AA F+ E
Sbjct: 408 NRTVFLGNLHTKTKGHEICDLIRHGGLQDFHYIPEKHICFVTFITYSAANAFHDYLAEEE 467
Query: 705 IILHGNVLKVGWGQNPGPLPKNIALAVTVGASRNVYVSLPDKAFKDKFINDPQFKEYQNR 764
++LHG +KVGWG+ GPLP+ + ++ +GASRNVY S I+D E
Sbjct: 468 VLLHGRRIKVGWGKESGPLPRVLEDSILMGASRNVYFS---------HISDSLTTE---- 514
Query: 765 YKIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINFMNISSAIKLV 809
+L+ YG +E + + + ++ + NIS+A+K V
Sbjct: 515 -------ELELILRQYGEIESIKYLKNRSSGFVAYTNISNAMKAV 552
Score = 79.0 bits (193), Expect = 4e-14
Identities = 57/223 (25%), Positives = 98/223 (43%), Gaps = 32/223 (14%)
Query: 621 PPQITQTIQNQYSKSIQAVNAGMEHRTVYIGNINPRSKAEDICNVVRGGILQHIKWVSHK 680
PP Q Q+S + ++ R + +GN+ K ++ +++ G L+ I+ K
Sbjct: 183 PPPFAQQPAEQFSPFNSEYESLLDFRALILGNLPVDYKISELLSLIHSGPLEKIQSNPGK 242
Query: 681 RICFVTFIETAAAVQFYANTTLEPIILHGNVLKVGWGQNPGPLPKNIA-LAVTVGASRNV 739
R +TF+++A A FY I HG LK+ + + P PLP++I ASRNV
Sbjct: 243 RRIIITFLDSADAFFFYERYHPRGFIFHGRPLKLTFAR-PSPLPESIQNFCSNTAASRNV 301
Query: 740 YVSLPDKAFKDKFINDPQFKEYQNRYKIPNIAQLKSDFGAYGTMEQVNFHSDGHCCWINF 799
++ ++ +K +++ FG +G +E + S + +++F
Sbjct: 302 FIGNLPSSYHEK--------------------EIEEAFGKFGKIEHIKILSKKNIAFVHF 341
Query: 800 MNISSAIKLVEEYSDTKDNLFHKKTEGRYVGLIIGYGKDRCGN 842
+NI AIK+V S D Y I +G DRC N
Sbjct: 342 LNIRDAIKVVRTLSCDPD----------YHSWRIFFGSDRCAN 374
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.315 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,685,722
Number of Sequences: 60738
Number of extensions: 2407869
Number of successful extensions: 4638
Number of sequences better than 1.0e-05: 4
Number of HSP's better than 0.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4609
Number of HSP's gapped (non-prelim): 15
length of query: 1151
length of database: 30,389,216
effective HSP length: 117
effective length of query: 1034
effective length of database: 23,282,870
effective search space: 24074487580
effective search space used: 24074487580
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)