ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0424 good O KOG1339 Posttranslational modification, protein turnover, chaperones Aspartyl protease
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0424 133636 135180 515
(515 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
Hs22063875 [O] KOG1339 Aspartyl protease 95 2e-19
Hs22063872 [O] KOG1339 Aspartyl protease 95 2e-19
Hs4505757 [O] KOG1339 Aspartyl protease 93 8e-19
7290034 [O] KOG1339 Aspartyl protease 88 4e-17
7303185 [O] KOG1339 Aspartyl protease 83 1e-15
Hs22063919 [O] KOG1339 Aspartyl protease 80 1e-14
Hs4503145 [O] KOG1339 Aspartyl protease 79 2e-14
CE20430 [O] KOG1339 Aspartyl protease 74 4e-13
CE21685 [O] KOG1339 Aspartyl protease 74 7e-13
7296074 [O] KOG1339 Aspartyl protease 73 1e-12
7297766 [O] KOG1339 Aspartyl protease 72 2e-12
7296076 [O] KOG1339 Aspartyl protease 68 4e-11
YPL154c [O] KOG1339 Aspartyl protease 67 6e-11
CE16843 [O] KOG1339 Aspartyl protease 66 1e-10
7300255 [O] KOG1339 Aspartyl protease 66 1e-10
7297765 [O] KOG1339 Aspartyl protease 66 1e-10
7297427 [O] KOG1339 Aspartyl protease 65 2e-10
Hs4503143 [O] KOG1339 Aspartyl protease 64 5e-10
CE21681 [O] KOG1339 Aspartyl protease 63 9e-10
7304149 [O] KOG1339 Aspartyl protease 63 9e-10
CE09539 [O] KOG1339 Aspartyl protease 62 2e-09
CE09738 [O] KOG1339 Aspartyl protease 61 5e-09
YIR039c [O] KOG1339 Aspartyl protease 60 1e-08
7300254 [O] KOG1339 Aspartyl protease 59 1e-08
CE19495 [O] KOG1339 Aspartyl protease 57 5e-08
CE03567 [O] KOG1339 Aspartyl protease 57 7e-08
7296075 [O] KOG1339 Aspartyl protease 57 7e-08
7300253 [O] KOG1339 Aspartyl protease 57 9e-08
CE21683 [O] KOG1339 Aspartyl protease 55 2e-07
YLR121c [O] KOG1339 Aspartyl protease 54 7e-07
YIL015w [O] KOG1339 Aspartyl protease 54 7e-07
At2g36670 [O] KOG1339 Aspartyl protease 51 4e-06
>Hs22063875 [O] KOG1339 Aspartyl protease
Length = 325
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/302 (26%), Positives = 134/302 (43%), Gaps = 48/302 (15%)
Query: 146 DNVKRAADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENY-PVS 204
D+ + T S+ Y +G+ +G + D + V ++ T N FG++ P F Y P
Sbjct: 59 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDT-NQIFGLSETEPGSFLYYAPFD 117
Query: 205 GIFGL--PXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTEN 262
GI GL P + +S + FS+ + A + ++
Sbjct: 118 GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADD-----------------QS 160
Query: 263 KGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSY 322
+ I G + YTG +++ +T E YWQ+ +DS+ +N +A+ G Q+
Sbjct: 161 GSVVIFGGIDSSYYTGSLNWVP-VTVEG-YWQITVDSITMNGEAI-----ACAEGCQA-- 211
Query: 323 IRSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEILS---LEINGVKWP 379
IVD+GT+LL PT ++ + S + + + C++ L INGV++P
Sbjct: 212 ----IVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYP 267
Query: 380 ISSEEYLGEAYPQDSYYYGYCVSNIQGLELD----ESWILGAVFLKDKYAVFDVQNQQFG 435
+ Y+ ++ G C+S QG+ L E WILG VF++ + VFD N Q G
Sbjct: 268 VPPSAYILQSE-------GSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVG 320
Query: 436 LA 437
LA
Sbjct: 321 LA 322
>Hs22063872 [O] KOG1339 Aspartyl protease
Length = 325
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/302 (26%), Positives = 134/302 (43%), Gaps = 48/302 (15%)
Query: 146 DNVKRAADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENY-PVS 204
D+ + T S+ Y +G+ +G + D + V ++ T N FG++ P F Y P
Sbjct: 59 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDT-NQIFGLSETEPGSFLYYAPFD 117
Query: 205 GIFGL--PXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTEN 262
GI GL P + +S + FS+ + A + ++
Sbjct: 118 GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADD-----------------QS 160
Query: 263 KGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSY 322
+ I G + YTG +++ +T E YWQ+ +DS+ +N +A+ G Q+
Sbjct: 161 GSVVIFGGIDSSYYTGSLNWVP-VTVEG-YWQITVDSITMNGEAI-----ACAEGCQA-- 211
Query: 323 IRSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEILS---LEINGVKWP 379
IVD+GT+LL PT ++ + S + + + C++ L INGV++P
Sbjct: 212 ----IVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYP 267
Query: 380 ISSEEYLGEAYPQDSYYYGYCVSNIQGLELD----ESWILGAVFLKDKYAVFDVQNQQFG 435
+ Y+ ++ G C+S QG+ L E WILG VF++ + VFD N Q G
Sbjct: 268 VPPSAYILQSE-------GSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVG 320
Query: 436 LA 437
LA
Sbjct: 321 LA 322
>Hs4505757 [O] KOG1339 Aspartyl protease
Length = 388
Score = 93.2 bits (230), Expect = 8e-19
Identities = 89/350 (25%), Positives = 145/350 (41%), Gaps = 50/350 (14%)
Query: 102 AYFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFS-TDNVKRAADESTFS 158
AYF ++IG + + ++ D+GS+ LWV F+ +++ + + TFS
Sbjct: 72 AYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFS 131
Query: 159 LIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYPVSGIFGL--PXXXXX 215
L Y SG+ +G D + V + N FG++ P F GI GL P
Sbjct: 132 LQYGSGSLTGFFGYDTLTVQSIQVP-NQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVD 190
Query: 216 XXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDL 275
+ + A++ FS+ + G + G + L
Sbjct: 191 EATTAMQGMVQEGALTSPVFSVYLSNQQGSSG----------------GAVVFGGVDSSL 234
Query: 276 YTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLL 335
YTG I++A + + YWQ+ I+ + QA + + G Q+ IVD+GT+LL
Sbjct: 235 YTGQIYWAPV--TQELYWQIGIEEFLIGGQASGWCSE----GCQA------IVDTGTSLL 282
Query: 336 ILPTQDALDLHTFFVNSVSDGTNFAIPCNSTE---ILSLEINGVKWPISSEEYLGEAYPQ 392
+P Q L + F + CNS + L+ INGV++P+ Y+
Sbjct: 283 TVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNN-- 340
Query: 393 DSYYYGYCVSNIQGLELDES-----WILGAVFLKDKYAVFDVQNQQFGLA 437
GYC ++ L WILG VFL+ Y+V+D+ N + G A
Sbjct: 341 -----GYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFA 385
>7290034 [O] KOG1339 Aspartyl protease
Length = 407
Score = 87.8 bits (216), Expect = 4e-17
Identities = 99/358 (27%), Positives = 152/358 (41%), Gaps = 51/358 (14%)
Query: 91 MSILSTDSNTQAYFVNVTIGDEIYPLVV--DSGSAYLWVYGXXXXXXXXXXXXLFSTDNV 148
M LS N Q Y+ N++IG +V D+GS+ LWV G +F +
Sbjct: 66 MEHLSNYDNFQ-YYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKS 124
Query: 149 KR-AADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFG-VANEVPDIFENYPVSGI 206
A+ + FS+ Y +G+ SG + D + L T Q+ TFG V E F + GI
Sbjct: 125 STYVANGTAFSITYGTGSVSGYLSVDCVGFAGL-TIQSQTFGEVTTEQGTNFVDAYFDGI 183
Query: 207 FGL--PXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKG 264
G+ P + + + FS + +DN + +T G
Sbjct: 184 LGMGFPSLAVDGVTPTFQNMMQQGLVQSPVFSFFL-----RDNGS---------VTFYGG 229
Query: 265 LFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIR 324
I+G LY+G + Y +++ + YW+ + D + V S ++ S
Sbjct: 230 ELILGGSDPSLYSGSLTYVNVV--QAAYWKFQTDYIKVGSTSI-------------STFA 274
Query: 325 SGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEI--LSLEINGVKWPISS 382
I D+GT+L+I P Q D + N+ S+G C+ST L + INGV + I +
Sbjct: 275 QAIADTGTSLIIAP-QAQYDQISQLFNANSEGL---FECSSTSYPDLIININGVDFKIPA 330
Query: 383 EEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLANKN 440
+ Y+ E +C IQ + D WI+G VFL Y FDV NQ+ G A N
Sbjct: 331 KYYIIEEED-------FCSLAIQSINQD-FWIMGDVFLGRIYTEFDVGNQRLGFAPVN 380
>7303185 [O] KOG1339 Aspartyl protease
Length = 404
Score = 82.8 bits (203), Expect = 1e-15
Identities = 86/351 (24%), Positives = 135/351 (37%), Gaps = 49/351 (13%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXX---XXXLFSTDNVKRAADESTF 157
YF +TIG + + ++ D+GS+ LWV F+ + F
Sbjct: 85 YFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRSTSHQVRGDHF 144
Query: 158 SLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPD-IFENYPVSGIFGLPXXXXXX 216
++ Y SG+ SG + D + V L TF A E+P IF GIFGL
Sbjct: 145 AIHYGSGSLSGFLSTDTVRVAGLEIRDQ-TFAEATEMPGPIFLAAKFDGIFGLAYRSISM 203
Query: 217 XXXX--XXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVED 274
+ E ++ FS+ + KD G G
Sbjct: 204 QRIKPPFYAMMEQGLLTKPIFSVYLSRNGEKDG----------------GAIFFGGSNPH 247
Query: 275 LYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTL 334
YTG+ Y + + YWQ+K+DS + + + E I+D+GT+
Sbjct: 248 YYTGNFTYVQV--SHRAYWQVKMDSAVIRNLELCQQGCEV------------IIDTGTSF 293
Query: 335 LILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEIL---SLEINGVKWPISSEEYLGEAYP 391
L LP A+ ++ + S F +PC+S L + + G ++ + S EY+
Sbjct: 294 LALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKITFTLGGRRFFLESHEYVFRDIY 353
Query: 392 QDSYYYGYCVSNIQGLELDES----WILGAVFLKDKYAVFDVQNQQFGLAN 438
QD C S ++L WILG VFL Y FD++ + G A+
Sbjct: 354 QDRRI---CSSAFIAVDLPSPSGPLWILGDVFLGKYYTEFDMERHRIGFAD 401
>Hs22063919 [O] KOG1339 Aspartyl protease
Length = 267
Score = 79.7 bits (195), Expect = 1e-14
Identities = 60/213 (28%), Positives = 100/213 (46%), Gaps = 27/213 (12%)
Query: 228 NAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDLYTGDIHYASLIT 287
N + ME F I ++D T D+ ++ + I G + YTG +++ +T
Sbjct: 70 NYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLDDQSGSVVIFGGIDSSYYTGSLNWVP-VT 128
Query: 288 NENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLLILPTQDALDLHT 347
E YWQ+ +DS+ +N +A+ G Q+ IVD+GT+LL PT ++ +
Sbjct: 129 VEG-YWQITVDSITMNGEAI-----ACAEGCQA------IVDTGTSLLTGPTSPIANIQS 176
Query: 348 FFVNSVSDGTNFAIPCNSTEILS---LEINGVKWPISSEEYLGEAYPQDSYYYGYCVSNI 404
S + + + C++ L INGV++P+ Y+ ++ G C+S
Sbjct: 177 DIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSE-------GSCISGF 229
Query: 405 QGLELD----ESWILGAVFLKDKYAVFDVQNQQ 433
QG+ L E WILG VF++ + VFD N Q
Sbjct: 230 QGMNLPTESGELWILGDVFIRQYFTVFDRANNQ 262
>Hs4503145 [O] KOG1339 Aspartyl protease
Length = 396
Score = 79.0 bits (193), Expect = 2e-14
Identities = 81/347 (23%), Positives = 139/347 (39%), Gaps = 44/347 (12%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAADES-TFSL 159
YF ++IG + + ++ D+GS+ LWV F + +FS+
Sbjct: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 160 IYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGL--PXXXXXXX 217
Y +G+ SG + D++ V L E F + GI GL P
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGV 197
Query: 218 XXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDLYT 277
+ N + + FS+ + + N + SE I G ++
Sbjct: 198 TPVFDNMMAQNLVDLPMFSVYMSS-NPEGGAGSE--------------LIFGGYDHSHFS 242
Query: 278 GDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLLIL 337
G +++ + + YWQ+ +D++ V + S G Q+ IVD+GT+L+
Sbjct: 243 GSLNWVPV--TKQAYWQIALDNIQVGGTVMFCSE-----GCQA------IVDTGTSLITG 289
Query: 338 PTQDALDLHTFFVNSVSDGTNFAIPCNSTEIL---SLEINGVKWPISSEEYLGEAYPQDS 394
P+ L + DG +A+ C + ++ + INGV + +S Y +
Sbjct: 290 PSDKIKQLQNAIGAAPVDG-EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGM 348
Query: 395 YYYGYCVSNIQGLELDES----WILGAVFLKDKYAVFDVQNQQFGLA 437
+ C S QGL++ WILG VF++ Y+VFD N + GLA
Sbjct: 349 QF---CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392
>CE20430 [O] KOG1339 Aspartyl protease
Length = 638
Score = 74.3 bits (181), Expect = 4e-13
Identities = 92/362 (25%), Positives = 135/362 (36%), Gaps = 47/362 (12%)
Query: 106 NVTIGDEIYPLVV--DSGSAYLWVYGXXXXXXXXXXXXLF-------STDNVKRAADEST 156
N+TIG V D+ SA LWV G L +T +
Sbjct: 65 NITIGSPPQSAFVFMDTTSANLWVMGSACTSVNCNDPLLGIIKHKFNTTKSTSFVKSNRK 124
Query: 157 FSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGL--PXXXX 214
F++ Y SG SG + D + + L Q FGVAN V F P+ GIFGL P
Sbjct: 125 FNIQYGSGECSGYLGTDTVEIGGLKI-QKQEFGVANIVDYDFGTRPIDGIFGLAWPALSV 183
Query: 215 XXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVED 274
L N + F++ D P + GL G L
Sbjct: 184 DQVTPPMQNLVSQNQLDAPIFTIFF---------DKRDPDYYYP---SNGLITYGGLDTK 231
Query: 275 LYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTL 334
+I Y + + YWQ K+D V + + +A+ + SS+ G+ S
Sbjct: 232 NCNANISYVPV--SSKTYWQFKVDGFQVGTYNRTVNRDQAIMDTGSSWF--GLPYSVIAG 287
Query: 335 LILPTQDALDLHTFFVNSVSDGTNFAIPC---NSTEILSLEINGVKWPISSEEYLGEAYP 391
+ T DL+ + + +PC NS L I K+PIS+ EY+ +
Sbjct: 288 IATQTNATWDLY---------ASVYTVPCSTMNSLPDLVFTIGAEKFPISAPEYVEDVGL 338
Query: 392 QDSYYYGYCVSNIQGLE---LDESWILGAVFLKDKYAVFDVQNQQFGLANKNENAILVPY 448
D G C + G++ S LG +F++ +VFDV N + G A+ L Y
Sbjct: 339 DD----GTCALAMYGIDASGFGPSVTLGNIFIRRYCSVFDVGNARIGFADAIHPNTLTYY 394
Query: 449 VN 450
N
Sbjct: 395 QN 396
>CE21685 [O] KOG1339 Aspartyl protease
Length = 829
Score = 73.6 bits (179), Expect = 7e-13
Identities = 84/362 (23%), Positives = 141/362 (38%), Gaps = 44/362 (12%)
Query: 96 TDSNTQAYFVNVTIGDEIYP--LVVDSGSAYLWVYGXXXXXX-------XXXXXXLFSTD 146
+D + + Y N T+G P LV+D+GSA +WV F T
Sbjct: 496 SDYSDEVYLGNFTVGTPPQPVSLVLDTGSANMWVIDASCDNMFCNGWIGSNYTRQKFDTS 555
Query: 147 NVKRAADEST-FSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSG 205
+ E+ FS+ Y G SG + D + + T + G+AN++ F P+ G
Sbjct: 556 KSSSFSRENRKFSIQYGKGLCSGYLGTDTVGLGGGLTIRKQELGIANKLDVDFAVQPMDG 615
Query: 206 IFGLPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGL 265
IFGL + + + + + FS+ + D +QA + G+
Sbjct: 616 IFGLAWPALAVDQITPPMQNLISQLDVPVFSVWL------------DRKIQASHGGSAGM 663
Query: 266 FIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRS 325
G + + Y L YWQ K+D V T SQ Y
Sbjct: 664 ITYGGIDTKNCDAGVTYVPLTAKT--YWQFKMDGFAVG------------TYSQYGY-NQ 708
Query: 326 GIVDSGTTLLILPTQDALDLHTFFVNSVSDGTN--FAIPCNSTEI---LSLEINGVKWPI 380
I D+G++ + P D+ T ++ D N + + C++ + L I G +P+
Sbjct: 709 VISDTGSSWISAPYAMINDIAT-QTHATWDEMNEIYTVKCSTMKTQPDLVFTIGGALFPV 767
Query: 381 SSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLANKN 440
S EY+ + D +S + SWILG VF++ ++D+ N + G AN +
Sbjct: 768 KSVEYILD-IGLDEGKCALAISPLMASGFGPSWILGDVFIRQYCNIYDIGNARIGFANAH 826
Query: 441 EN 442
+
Sbjct: 827 HS 828
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/299 (22%), Positives = 119/299 (39%), Gaps = 42/299 (14%)
Query: 103 YFVNVTIGDEIYP--LVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAADEST---- 156
Y N+T+G P +V+D+ SA LWV K ++S+
Sbjct: 68 YLANITVGTPPQPASVVLDTASANLWVIDAACNSQACNGNPGSGYTKQKFNPNKSSTFVK 127
Query: 157 ----FSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGL--P 210
FS+ Y SGT+SG + D + + L T + FGVA + + + P+ GIFGL P
Sbjct: 128 GTRRFSIQYGSGTSSGYLGTDVLQLGGL-TVKAQEFGVATNLGSVLGSEPMDGIFGLGWP 186
Query: 211 XXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGD 270
L + FS+ + D LQ GL G
Sbjct: 187 AISVDQVTPPMQNLISQKQLDAPLFSIWV------------DRKLQVSQGGTGGLITYGA 234
Query: 271 LVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDS 330
+ ++Y +L + YWQ +D V + + A+ +A++ + S+++ G+ +
Sbjct: 235 VDTKNCDAQVNYVAL--SSKTYWQFPMDGVAIGNYAM-MKQEQAISDTGSAWL--GLPNP 289
Query: 331 GTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEI---LSLEINGVKWPISSEEYL 386
++ T+ D + + + C++ + L I G+++P+ S EY+
Sbjct: 290 VLNAIVQQTKATYDWNYEI---------YTLDCSTMQTQPDLVFTIGGMQYPVKSIEYI 339
>7296074 [O] KOG1339 Aspartyl protease
Length = 393
Score = 72.8 bits (177), Expect = 1e-12
Identities = 83/363 (22%), Positives = 143/363 (38%), Gaps = 44/363 (12%)
Query: 83 VEVPVKPGMSILSTDSNTQAYFVN----VTIGDEIYPLVVDSGSAYLWVYGXXXXXXXXX 138
V V + G ++ T+ +Y N V++GD+ + + D+GS+ WV
Sbjct: 64 VNVTSESGKGVVITEPLINSYDTNFFGVVSVGDQSFTMQFDTGSSDFWVPSSHCRFCIKT 123
Query: 139 -XXXLFSTDNVKRAADEST-FSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPD 196
F N K T FS+ Y SG+ G V D + L QN G+ N + D
Sbjct: 124 CGNKFFRKSNSKSFRSSGTPFSITYGSGSVKGIVASDNVGFGDLKI-QNQGIGLVN-ISD 181
Query: 197 IFENYPVSGIFGLPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQ 256
S G+ V S I + I + + K ++
Sbjct: 182 -----SCSVFDGIAGFAFQQLSMTKSVPSFQQMIDQQLVEQPIFSFHLKSGSS------- 229
Query: 257 APLTENKGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVT 316
+ G I+G LY G + Y ++ E YW K+D + V+ +
Sbjct: 230 -----DGGSMILGGSNSSLYYGPLTYTNV--TEAKYWSFKLDFIAVHGK----------- 271
Query: 317 GSQSSYI-RSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTN-FAIPCNSTEILSLEIN 374
GS+SS I+D+GT+L++ P + L ++ + N + + C S L + +
Sbjct: 272 GSRSSRTGNKAIMDTGTSLIVGPVLEVLYINKDIGAEHNKTYNLYTVACESIPQLPIIVF 331
Query: 375 GVKWPISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQF 434
G I+ +E+ + + Y +C S + + WILG F+++ Y FD ++
Sbjct: 332 G----IAGKEFFVKPHTYVIRYDNFCFSAFMDMLGLQYWILGDAFMRENYVEFDWARRRM 387
Query: 435 GLA 437
G+A
Sbjct: 388 GIA 390
>7297766 [O] KOG1339 Aspartyl protease
Length = 391
Score = 72.4 bits (176), Expect = 2e-12
Identities = 86/360 (23%), Positives = 146/360 (39%), Gaps = 62/360 (17%)
Query: 97 DSNTQAYFVNVTIG--DEIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRA--- 151
+S Y+ + IG ++ + ++ D+GSA LWV D+ +
Sbjct: 70 NSMNNEYYGVIAIGTPEQRFNILFDTGSANLWVPSASCPASNTACQRHNKYDSSASSTYV 129
Query: 152 ADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYPVSGIFGLP 210
A+ F++ Y +G+ SG + D + + ++ QN TFG A P F + P +GI GL
Sbjct: 130 ANGEEFAIEYGTGSLSGFLSNDIVTIAGISI-QNQTFGEALSEPGTTFVDAPFAGILGLA 188
Query: 211 XXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTE--------- 261
+AI+++ G DN S+ L P+
Sbjct: 189 F----------------SAIAVD------GVTPPFDNMISQ-GLLDEPVISFYLKRQGTA 225
Query: 262 -NKGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQS 320
G I+G + LY G + Y + YWQ K++++ N + G Q+
Sbjct: 226 VRGGELILGGIDSSLYRGSLTYVPVSVPA--YWQFKVNTIKTNGTLL-------CNGCQA 276
Query: 321 SYIRSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEIL---SLEINGVK 377
I D+GT+L+ +P ++ + +DG F + C L +L I G
Sbjct: 277 ------IADTGTSLIAVPLAAYRKINRQLGATDNDGEAF-VRCGRVSSLPKVNLNIGGTV 329
Query: 378 WPISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
+ ++ +Y+ + Y C+S +E WILG VF+ Y VFD N++ G A
Sbjct: 330 FTLAPRDYIVKVTQNGQTY---CMSAFTYMEGLSFWILGDVFIGKFYTVFDKGNERIGFA 386
>7296076 [O] KOG1339 Aspartyl protease
Length = 405
Score = 67.8 bits (164), Expect = 4e-11
Identities = 81/352 (23%), Positives = 142/352 (40%), Gaps = 47/352 (13%)
Query: 97 DSNTQAYFVNVTIG--DEIYPLVVDSGSAYLWVYGXXXXXXXXX---XXXLFSTDNVKRA 151
+S Y+ + IG ++ + +V D+GSA LWV S+ +
Sbjct: 87 NSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDVACQQHNQYNSSASSTFV 146
Query: 152 ADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYPVSGIFGLP 210
+ FS+ Y +G+ SG + D + +N LA N TFG A P F + GI G+
Sbjct: 147 SSGQNFSIQYGTGSVSGYLAIDTVTINGLAIA-NQTFGEAVSQPGASFTDVAFDGILGMG 205
Query: 211 XXXXXXXXXXXXV--LSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFII 268
L E I F + N ++ D G +
Sbjct: 206 YQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLAR-----NGSAVDG----------GQLTL 250
Query: 269 GDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIV 328
G ++L G++ Y + + YWQ ++++ N ++ +G Q+ I
Sbjct: 251 GGTDQNLIAGEMTYTPV--TQQGYWQFAVNNITWNGTVIS-------SGCQA------IA 295
Query: 329 DSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCN---STEILSLEINGVKWPISSEEY 385
D+GT+L+ P+ + L+ + V ++ +PC+ S +L++ I G + + Y
Sbjct: 296 DTGTSLIAAPSAAYIQLNNL-IGGVPIQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVY 354
Query: 386 LGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
+ + Y + +Y C+S + WILG VFL Y+ FD + G A
Sbjct: 355 I-QTYTEGNYTT--CMSTFTDIGTG-FWILGDVFLGQYYSEFDFGQNRVGFA 402
>YPL154c [O] KOG1339 Aspartyl protease
Length = 405
Score = 67.0 bits (162), Expect = 6e-11
Identities = 76/361 (21%), Positives = 144/361 (39%), Gaps = 49/361 (13%)
Query: 90 GMSILSTDSNTQAYFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTD- 146
G + T+ Y+ ++T+G + + +++D+GS+ LWV + +
Sbjct: 78 GHDVPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSLACFLHSKYDHEA 137
Query: 147 NVKRAADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYPVSG 205
+ A+ + F++ Y +G+ G + +D + + L T F A P + F G
Sbjct: 138 SSSYKANGTEFAIQYGTGSLEGYISQDTLSIGDL-TIPKQDFAEATSEPGLTFAFGKFDG 196
Query: 206 IFGLPXXXXXXXXXXXXVLS--ESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENK 263
I GL + + + + ++F+ +G TS+D TEN
Sbjct: 197 ILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLG-------DTSKD-------TENG 242
Query: 264 GLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYI 323
G G + E + GDI + L YW++K + + + + + A
Sbjct: 243 GEATFGGIDESKFKGDITW--LPVRRKAYWEVKFEGIGLGDEYAELESHGAA-------- 292
Query: 324 RSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEILS---LEINGVKWPI 380
+D+GT+L+ LP+ A ++ + + CN+ + L NG + I
Sbjct: 293 ----IDTGTSLITLPSGLAEMINAEIGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTI 348
Query: 381 SSEEYLGEAYPQDSYYYGYCVSNIQGLELDESW----ILGAVFLKDKYAVFDVQNQQFGL 436
+Y E G C+S I ++ E I+G FL+ Y+++D+ N GL
Sbjct: 349 GPYDYTLEVS-------GSCISAITPMDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGL 401
Query: 437 A 437
A
Sbjct: 402 A 402
>CE16843 [O] KOG1339 Aspartyl protease
Length = 394
Score = 66.2 bits (160), Expect = 1e-10
Identities = 79/362 (21%), Positives = 149/362 (40%), Gaps = 55/362 (15%)
Query: 102 AYFVNVTIG-------DEIYPLVVDSGSAYLWVYGXX-----XXXXXXXXXXLFSTDNVK 149
AYF N+T+G ++ + +V+D+GS+ +WV F TD+
Sbjct: 65 AYFGNITLGTPIESTAEQTFLVVLDTGSSNVWVPDNSCGIDDKKSACTYKKKYFGTDSSS 124
Query: 150 RAADESTFSLIYSSGTASGDVYEDRIIVNKLA-TTQNFTFGVANEVPDIFENYPVSGIFG 208
D + FS+ Y +G+ASG +D + + ++ FG AN + F N + GI G
Sbjct: 125 YEKDGTPFSISYGTGSASGYFGKDTLCFSDTTLCIKSQIFGQANNIAPFFANQEIDGILG 184
Query: 209 LPXXXXXXXXXXXXVLS--ESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLF 266
L ++ E + F++ + K + G F
Sbjct: 185 LGFTDLAVHSVPPPFVNAVEQGLVDEPIFTVYLEHHGIKKEASG-------------GYF 231
Query: 267 IIGDLVEDLYTGDIHYASLIT----NENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSY 322
G D H +IT + YWQ ++ + +++ + + E ++ + +S+
Sbjct: 232 TYGGEDPD------HCGEIITWIPLTKAAYWQFRMQGIGIDNVNEHKNGWEVISDTGTSF 285
Query: 323 IRSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCN---STEILSLEINGVKWP 379
I G +I QD + + + SD ++ IPC+ + L ++IN + +
Sbjct: 286 I------GGPGKVI---QDIANKYGATYDEYSD--SYVIPCSEIKNLRSLKMKINDLTFE 334
Query: 380 ISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLANK 439
I + A+P DS + ++ G SWILG F++ + D++N++ GLA+
Sbjct: 335 IDPINLV--AHP-DSSECDLTLFDMYGGGFGPSWILGDPFIRQFCNIHDIKNKRIGLAHS 391
Query: 440 NE 441
+
Sbjct: 392 KQ 393
>7300255 [O] KOG1339 Aspartyl protease
Length = 395
Score = 66.2 bits (160), Expect = 1e-10
Identities = 76/342 (22%), Positives = 135/342 (39%), Gaps = 45/342 (13%)
Query: 107 VTIGDEIYP--LVVDSGSAYLWVYGXXXXXXXXX---XXXLFSTDNVKRAADESTFSLIY 161
++IG P ++ D+GSA LWV ++ + D FS+ Y
Sbjct: 85 ISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPDGRRFSIAY 144
Query: 162 SSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPD-IFENYPVSGIFGLPXXXXXXXXXX 220
+G+ SG + +D + + +L QN TFG+A P F + +GI GL
Sbjct: 145 GTGSLSGRLAQDTVAIGQLVV-QNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAELGIK 203
Query: 221 XXVLSESNAISMEK--FSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDLYTG 278
S + +++ FS + S+ G + G + + ++G
Sbjct: 204 PLFESMCDQQLVDECVFSFYLKRNGSE---------------RKGGELLFGGVDKTKFSG 248
Query: 279 DIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLLILP 338
+ Y L YWQ +D + V G++ + R I D+GT+LL P
Sbjct: 249 SLTYVPL--THAGYWQFPLDVI-------------EVAGTRINQNRQAIADTGTSLLAAP 293
Query: 339 TQDALDLHTFFVNSVSDGTNFAIPCNSTEILS---LEINGVKWPISSEEYLGEAYPQDSY 395
++ L +++ + + + C+ + L I G ++ + +Y+ A D
Sbjct: 294 PREYLIINSLLGGLPTSNNEYLLNCSEIDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGS 353
Query: 396 YYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
C+S ++ E WILG VF+ Y FD ++ G A
Sbjct: 354 --SICLSAFTLMDA-EFWILGDVFIGRYYTAFDAGQRRIGFA 392
>7297765 [O] KOG1339 Aspartyl protease
Length = 423
Score = 65.9 bits (159), Expect = 1e-10
Identities = 81/360 (22%), Positives = 146/360 (40%), Gaps = 45/360 (12%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXX---XXXLFSTDNVKRAADESTF 157
Y + + IG + + L D+GS+ LWV S+ + D F
Sbjct: 74 YTIRLCIGTPPQCFNLQFDTGSSDLWVPSVKCSSTNEACQKHNKYNSSASSSHVEDGKGF 133
Query: 158 SLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVP-DIFENYPVSGIFGLPXXXXXX 216
S+ Y SG+ SG + D + ++ + +N TF A + P F N GI G+
Sbjct: 134 SIQYGSGSLSGFLSTDTVDIDGM-VIRNQTFAEAIDEPGSAFVNTIFDGIIGMAFASISG 192
Query: 217 XXXX-XXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDL 275
+ + FS+ + +D T +++ G I G + +
Sbjct: 193 GVTTPFDNIIRQGLVKHPVFSVYL----RRDGT-----------SQSGGEVIWGGIDRSI 237
Query: 276 YTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLL 335
Y G I+Y + + YWQ +SV + + G Q+ I D+GT+L+
Sbjct: 238 YRGCINYVPV--SMPAYWQFTANSVKIEGILL-------CNGCQA------IADTGTSLI 282
Query: 336 ILPTQDALDLHTFF-VNSVSDGTNFAIPCNS---TEILSLEINGVKWPISSEEYLGEAYP 391
+P + ++ DG F + C+S ++L I G + ++ ++Y+ +
Sbjct: 283 AVPLRAYKAINKVLNATDAGDGEAF-VDCSSLCRLPNVNLNIGGTTYTLTPKDYIYKVQA 341
Query: 392 QDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLANKNENAILVPYVNS 451
++ C+S L+ + WILG +FL Y VFDV ++ G A +++ Y +S
Sbjct: 342 DNN--QTLCLSGFTYLQGNLLWILGDIFLGKVYTVFDVGKERIGFAKLKKHSSYRVYASS 399
>7297427 [O] KOG1339 Aspartyl protease
Length = 372
Score = 65.1 bits (157), Expect = 2e-10
Identities = 74/345 (21%), Positives = 135/345 (38%), Gaps = 40/345 (11%)
Query: 96 TDSNTQAYFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLF-STDNVKRAA 152
++S AY+ ++IG + + ++ DSGS+ LWV + S+ + A
Sbjct: 62 SNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVA 121
Query: 153 DESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGLPXX 212
+ +FS+ Y +G+ +G + D + VN L+ NE F + GI G+
Sbjct: 122 NGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYE 181
Query: 213 XXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLV 272
+ ++ ++++ L DN+ + + G I G
Sbjct: 182 SLAV-----------DGVAPPFYNMVSQGL--VDNSVFSFYLARDGTSTMGGELIFGGSD 228
Query: 273 EDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGT 332
LY+G + Y + +E YWQ + ++ G I D+GT
Sbjct: 229 ASLYSGALTYVPI--SEQGYWQFTM-------------AGSSIDGYSLCDDCQAIADTGT 273
Query: 333 TLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEILSLEINGVKWPISSEEYLGEAYPQ 392
+L++ P + L +N DG +S ++ I G + + Y+ ++
Sbjct: 274 SLIVAPYNAYITLSEI-LNVGEDGYLDCSSVSSLPDVTFNIGGTNFVLKPSAYIIQSD-- 330
Query: 393 DSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
G C+S + + D WILG VF+ Y FD+ N + G A
Sbjct: 331 -----GNCMSAFEYMGTD-FWILGDVFIGQYYTEFDLGNNRIGFA 369
>Hs4503143 [O] KOG1339 Aspartyl protease
Length = 412
Score = 63.9 bits (154), Expect = 5e-10
Identities = 81/360 (22%), Positives = 139/360 (38%), Gaps = 56/360 (15%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAA---DESTF 157
Y+ + IG + + +V D+GS+ LWV ++ K + + ++F
Sbjct: 79 YYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSF 138
Query: 158 SLIYSSGTASGDVYEDRIIVNKLATT----------QNFTFGVANEVPDI-FENYPVSGI 206
+ Y SG+ SG + +D + V + + + FG A + P I F GI
Sbjct: 139 DIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGI 198
Query: 207 FGL--PXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKG 264
G+ P L + + FS + S+D P + G
Sbjct: 199 LGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYL----SRD-----------PDAQPGG 243
Query: 265 LFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIR 324
++G Y G + Y ++ YWQ+ +D V V S + G ++
Sbjct: 244 ELMLGGTDSKYYKGSLSYLNV--TRKAYWQVHLDQVEVAS-----GLTLCKEGCEA---- 292
Query: 325 SGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEIL---SLEINGVKWPIS 381
IVD+GT+L++ P + +L + IPC L +L++ G + +S
Sbjct: 293 --IVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLS 350
Query: 382 SEEYLGEAYPQDSYYYGYCVSNIQGLELDES----WILGAVFLKDKYAVFDVQNQQFGLA 437
E+Y + C+S G+++ WILG VF+ Y VFD N + G A
Sbjct: 351 PEDYTLKVSQAGKTL---CLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFA 407
>CE21681 [O] KOG1339 Aspartyl protease
Length = 396
Score = 63.2 bits (152), Expect = 9e-10
Identities = 80/351 (22%), Positives = 140/351 (39%), Gaps = 45/351 (12%)
Query: 103 YFVNVTIGDEIYP--LVVDSGSAYLWVYGXXXXXXX--------XXXXXLFSTDNVKRAA 152
Y N+T+G P +V+D+GS+ LWV +T +
Sbjct: 68 YLGNITLGTPPQPATVVLDTGSSNLWVIDAACKTQACNGYPDSGYTKQKFDTTKSTTFVK 127
Query: 153 DESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGLPXX 212
+ FS+ Y SG+ +G + +D + L T Q+ FGV+ + D+F PV GI GL
Sbjct: 128 ETRKFSIQYGSGSCNGYLGKDVLNFGGL-TVQSQEFGVSTHLADVFGYQPVDGILGL--- 183
Query: 213 XXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLV 272
V N I+ ++ L++ T D LQ GL G +
Sbjct: 184 GWPALAVDQVVPPMQNLIAQKQ-------LDAPLFTVWLDRNLQIAQGTPGGLITYGAID 236
Query: 273 EDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGT 332
+ Y L + YWQ +D+ V + + + ++ + +S++ G ++
Sbjct: 237 TVNCAKQVTYVPL--SAKTYWQFPLDAFAVGTYS-ETKKDQVISDTGTSWL--GAPNTIV 291
Query: 333 TLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEI---LSLEINGVKWPISSEEYLGEA 389
+ ++ T+ D T + + C++ + L I G ++P+ S EY+ +
Sbjct: 292 SAIVKQTKAVFDWSTEL---------YTVDCSTMKTQPDLIFTIGGAQFPVKSVEYVLDL 342
Query: 390 YPQDSYYYGYC---VSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
G C V ++ SWILG F++ V+D+ N Q G A
Sbjct: 343 ----QLGGGKCALAVFSMGSGGFGPSWILGDTFIRQYCNVYDIGNGQIGFA 389
>7304149 [O] KOG1339 Aspartyl protease
Length = 392
Score = 63.2 bits (152), Expect = 9e-10
Identities = 75/351 (21%), Positives = 131/351 (36%), Gaps = 48/351 (13%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAA---DESTF 157
Y+ + IG + + +V D+GS+ LWV D K + + F
Sbjct: 73 YYGPIAIGSPPQNFRVVFDTGSSNLWVPSKKCHLTNIACLMHNKYDASKSKTYTKNGTEF 132
Query: 158 SLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPD-IFENYPVSGIFGLPXXXXXX 216
++ Y SG+ SG + D + + L ++ TF A P +F GI GL
Sbjct: 133 AIQYGSGSLSGYLSTDTVSIAGL-DIKDQTFAEALSEPGLVFVAAKFDGILGLGYNSISV 191
Query: 217 XXXX--XXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVED 274
+ E IS FS + + P + G I G +
Sbjct: 192 DKVKPPFYAMYEQGLISAPVFSFYLN---------------RDPASPEGGEIIFGGSDPN 236
Query: 275 LYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTL 334
YTG+ Y L YWQ+K+D+ + + + I D+GT+L
Sbjct: 237 HYTGEFTY--LPVTRKAYWQIKMDAASIGDLQLCKGGCQV------------IADTGTSL 282
Query: 335 LILPTQDALDLHTFFVNSVSDGTNFAIPCN---STEILSLEINGVKWPISSEEYLGEAYP 391
+ P ++A ++ + G + + C+ ++ + G + + ++Y+
Sbjct: 283 IAAPLEEATSINQKIGGTPIIGGQYVVSCDLIPQLPVIKFVLGGKTFELEGKDYILRVAQ 342
Query: 392 QDSYYYGYCVSNIQGLELDES----WILGAVFLKDKYAVFDVQNQQFGLAN 438
C+S GL++ WILG VF+ Y FD+ N + G A+
Sbjct: 343 MGKTI---CLSGFMGLDIPPPNGPLWILGDVFIGKYYTEFDMGNDRVGFAD 390
>CE09539 [O] KOG1339 Aspartyl protease
Length = 393
Score = 62.4 bits (150), Expect = 2e-09
Identities = 78/343 (22%), Positives = 134/343 (38%), Gaps = 34/343 (9%)
Query: 103 YFVNVTIGDEIYP--LVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAADESTFSLI 160
Y N+TIG P +V+D+GS+ LWV G ST + A+ + +
Sbjct: 73 YLGNITIGTPPQPFLVVLDTGSSNLWVPGPSCDGSCKGKREYQSTKSSTFKANGKPWQIQ 132
Query: 161 YSSGTASGDVYEDRI----IVNKLATTQNFTFGVANEVPDIFENYPVSGIFGLPXXXXXX 216
Y SG A G + ED + + K + TFG+A + F+N GI GL
Sbjct: 133 YGSGNAKGYLGEDTVAFGAVTEKQLPVPSTTFGIATHISSDFKNDAAEGILGLAFTSLAV 192
Query: 217 XXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDLY 276
+++ N +++ L L K + G+F G +
Sbjct: 193 DHVVPPLINAINQGLLDQ-PLFTVWLEHKGSANDVGG----------GVFTYGAVDTTNC 241
Query: 277 TGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLLI 336
I Y L + Y+Q DS + S + N + ++ + +S++ G ++
Sbjct: 242 GPVIAYQPL--SSATYYQFVADSFKLGSYS-NSKKYQVISDTGTSFL------GGPKAVV 292
Query: 337 LPTQDALDLHTFFVNSVSDGTNFAIPC-NSTEILSLEINGVKWPISSEEYLGEAYPQDSY 395
AL T+ N S + +PC + L + I G + I+ Y+ + D+
Sbjct: 293 AGLASALGA-TYHSNDDS----YYVPCATNIGTLDITIGGKVYSINPVNYIVDVGMGDTC 347
Query: 396 YYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLAN 438
+ N G +WILG F++ ++D+ Q+ G AN
Sbjct: 348 VFAAFAFNNFG--FGPAWILGDPFIRQFCNIYDIGGQRMGFAN 388
>CE09738 [O] KOG1339 Aspartyl protease
Length = 389
Score = 60.8 bits (146), Expect = 5e-09
Identities = 90/351 (25%), Positives = 142/351 (39%), Gaps = 41/351 (11%)
Query: 95 STDSNTQAYFVNVTIG--DEIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAA 152
+TD Y N+T+G D+ + +V+D+GSA L + G + A
Sbjct: 64 TTDYVYYEYMGNITVGTPDQNFIVVLDTGSANLLIPGTNCTTYCEKKRLFNEKASSTYIA 123
Query: 153 DESTFSLIYSSGTASGDVYEDRIIVN-----KLATTQNFTFGVANEVPDIFENYPVSGIF 207
+ + Y+SG A G + D + + +LA +++ GVA+ V F+ P GIF
Sbjct: 124 TNRPWQIKYASGDAYGTLGIDTVKIGGSGEAQLAIPRSY-LGVADTVGSDFKWSPKEGIF 182
Query: 208 GLPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFI 267
GL ++ NAI+ L + T+ AP T G F
Sbjct: 183 GLAFTALAVDNITPPII---NAINQ--------GLLDQPLFTTWFGQRGAPGTSASGAFT 231
Query: 268 IGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGI 327
G L ++ I YA L TN H+ QA FS V S ++Y I
Sbjct: 232 YGGLDKNHCGPVIGYAEL-TNARHF----------QFQATGFSLGSYV--STTTY--EVI 276
Query: 328 VDSGTTLLILPTQDALDLHTFFVNSVSDGTN--FAIPCNSTE-ILSLEINGVKWPISSEE 384
D+ T+ L P Q A+D + D TN F IPC++ + ++I + I +
Sbjct: 277 TDTATSFLCGP-QAAIDNLAKAAGATWDPTNQVFNIPCDADAGPIKMKIGQFNYVIRANN 335
Query: 385 YLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFG 435
Y+ + +S + N G SWILG F++ V D+ ++ G
Sbjct: 336 YILKI-DTNSCLFAAIPQNYAGF--GPSWILGGPFMRQYCNVHDIGQKRVG 383
>YIR039c [O] KOG1339 Aspartyl protease
Length = 537
Score = 59.7 bits (143), Expect = 1e-08
Identities = 72/306 (23%), Positives = 126/306 (40%), Gaps = 25/306 (8%)
Query: 143 FSTDNVKRAADESTF-SLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENY 201
F N + +TF + Y GT Y ++ + T +FTFGV+N D N
Sbjct: 145 FDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVSFENITLNDFTFGVSN---DTIGN- 200
Query: 202 PVSGIFG--LPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPL 259
SGI G LP L+ + I + F + + K N + L P
Sbjct: 201 -PSGILGISLPIAEFTDGIEYALALNRTPFI-YDNFPMELKN-QGKINKIAYSLFLNGP- 256
Query: 260 TENKGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQ 319
+ G + G + + YTG ++ ++ N + + +Q+V SE+ +
Sbjct: 257 DAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNP--GMIITAQSVAILDSESGNKTV 314
Query: 320 SSYIRSGIVDSGTTLLILPTQDALDLHTFFVNSVS-DGTNFAIPCNSTE--ILSLEINGV 376
S ++DSGTT LPT+ A + F S D + C+ +LS++ G
Sbjct: 315 SDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCSKVNDTLLSVDFGGF 374
Query: 377 KWPISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGL 436
+ ++ A + CV N++ + + +++LG FL D Y V+D++N + +
Sbjct: 375 NISANISNFVTSAKDR-------CVLNVK--QSESTYMLGDAFLVDAYVVYDLENYEISI 425
Query: 437 ANKNEN 442
A + N
Sbjct: 426 AQASFN 431
>7300254 [O] KOG1339 Aspartyl protease
Length = 309
Score = 59.3 bits (142), Expect = 1e-08
Identities = 76/343 (22%), Positives = 138/343 (40%), Gaps = 47/343 (13%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXX---XXXXXXXXXXLFSTDNVKRAADESTF 157
Y+ + +G+ + + ++ D+GS+ W+ S+ + D F
Sbjct: 3 YYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGRNF 62
Query: 158 SLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYPVSGIFGLPXXXXXX 216
+L Y SG G + +D + + A +FTFG + + F + G+ GL
Sbjct: 63 TLRYGSGMVVGYLSKDTMHIAG-AELPHFTFGESLFLQHFAFSSVKFDGLVGL------- 114
Query: 217 XXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDLY 276
VLS SN + L E L + + G E +
Sbjct: 115 ---GLGVLSWSNTTPFLELLCAQRLL--------EKCVFSVYLRRDPREIVFGGFDESKF 163
Query: 277 TGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLLI 336
G +HY + ++ H W L+I V ++ + G +S+ I+D+GT+L++
Sbjct: 164 EGKLHYVPV--SQWHTWSLQISKSSVGTKQI---------GGKSN----AILDTGTSLVL 208
Query: 337 LPTQDALDLHTFFVNSVSDGTNFAIPCNSTEI--LSLEINGVKWPISSEEYLGEAYPQDS 394
+P Q +L + +G F + C S + +++ I +P++S +Y+ E
Sbjct: 209 VPQQTYHNLLNTLSAKLQNGY-FVVACKSGSLPNINILIGDKVFPLTSSDYIMEVLLDRK 267
Query: 395 YYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
CV I + W+LG +FL+ Y VFD ++ GLA
Sbjct: 268 ---PACVLAIAPINRG-FWVLGDIFLRRYYTVFDATEKRIGLA 306
>CE19495 [O] KOG1339 Aspartyl protease
Length = 398
Score = 57.4 bits (137), Expect = 5e-08
Identities = 80/360 (22%), Positives = 140/360 (38%), Gaps = 44/360 (12%)
Query: 94 LSTDSNTQAYFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRA 151
LS SN Q Y+ VTIG + + ++ D+GS+ LWV D K +
Sbjct: 61 LSDYSNAQ-YYGPVTIGTPPQNFQVLFDTGSSNLWVPCANCPFGDIACRMHNRFDCKKSS 119
Query: 152 ADEST---FSLIYSSGTASGDVYEDRIIVNK---LATTQNFTFGVANEVPDI-FENYPVS 204
+ +T F + Y +G+ G V D + T +N A P I F
Sbjct: 120 SCTATGASFEIQYGTGSMKGTVDNDVVCFGHDTTYCTDKNQGLACATSEPGITFVAAKFD 179
Query: 205 GIFGLPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKG 264
GIFG+ N IS + + K+ + + A N G
Sbjct: 180 GIFGMGWDTISV-----------NKISQPMDQIFANSAICKNQLFAFWLSRDANDITNGG 228
Query: 265 LFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIR 324
+ + + Y G+I + L++ + YW++K+ SV ++ ++
Sbjct: 229 EITLCETDPNHYVGNIAWEPLVSED--YWRIKLASVVIDGTTYTSGPIDS---------- 276
Query: 325 SGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCN---STEILSLEINGVKWPIS 381
IVD+GT+LL PT + + + C+ S ++ + G + +
Sbjct: 277 --IVDTGTSLLTGPTDVIKKIQHKIGGIPLFNGEYEVECSKIPSLPNITFNLGGQNFDLQ 334
Query: 382 SEEYLGEAYPQDSYYYGYCVSNIQGLELDES----WILGAVFLKDKYAVFDVQNQQFGLA 437
++Y+ + + C+S G+++ WILG VF+ Y+VFD N++ G A
Sbjct: 335 GKDYILQM--SNGNGGSTCLSGFMGMDIPAPAGPLWILGDVFIGRFYSVFDHGNKRVGFA 392
>CE03567 [O] KOG1339 Aspartyl protease
Length = 444
Score = 57.0 bits (136), Expect = 7e-08
Identities = 79/350 (22%), Positives = 128/350 (36%), Gaps = 48/350 (13%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLFSTDNVKRAA---DESTF 157
YF ++IG + + ++ D+GS+ LW+ D+ + D
Sbjct: 94 YFGTISIGTPAQNFTVIFDTGSSNLWIPSKKCPFYDIACMLHHRYDSKSSSTYKEDGRKM 153
Query: 158 SLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYPVSGIFGL--PXXXX 214
++ Y +G+ G + +D + V + ++ F A P I F GI G+ P
Sbjct: 154 AIQYGTGSMKGFISKDSVCVAGVCA-EDQPFAEATSEPGITFVAAKFDGILGMAYPEIAV 212
Query: 215 XXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVED 274
L E + FS + + P +E G G +
Sbjct: 213 LGVQPVFNTLFEQKKVPSNLFSFWLN---------------RNPDSEIGGEITFGGIDSR 257
Query: 275 LYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTL 334
Y I Y + YWQ K+D V V S + S G Q+ I D+GT+L
Sbjct: 258 RYVEPITYVPV--TRKGYWQFKMDKV-VGSGVLGCSN-----GCQA------IADTGTSL 303
Query: 335 LILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEIL---SLEINGVKWPISSEEYLGEAYP 391
+ P + F + I C+ L S I G ++ + E+Y+ +
Sbjct: 304 IAGPKAQIEAIQNFIGAEPLIKGEYMISCDKVPTLPPVSFVIGGQEFSLKGEDYVLKVSQ 363
Query: 392 QDSYYYGYCVSNIQGLELDES----WILGAVFLKDKYAVFDVQNQQFGLA 437
C+S G++L E WILG VF+ Y+VFD + G A
Sbjct: 364 GGKTI---CLSGFMGIDLPERVGELWILGDVFIGRYYSVFDFDQNRVGFA 410
>7296075 [O] KOG1339 Aspartyl protease
Length = 410
Score = 57.0 bits (136), Expect = 7e-08
Identities = 85/397 (21%), Positives = 153/397 (38%), Gaps = 54/397 (13%)
Query: 60 NINDALSKQALQGQATAKSSTKNVEVPVK-PGMSILSTDS--NTQAYFVNVTIGDEIYPL 116
NI + L +++ + + K PG + + ++ NT+ Y+ + G+ L
Sbjct: 45 NIKNELKTLSIKHNLNVDDTKAKTKTDTKVPGSKVATLENLYNTE-YYTTLGFGNPPQDL 103
Query: 117 --VVDSGSAYLWVYGX---XXXXXXXXXXXLFSTDNVKRAADESTFSLIYSSGTASGDV- 170
++D+GSA LWV S+ + A + F++ Y S + G +
Sbjct: 104 KVLIDTGSANLWVLSSKCPDSVAPCANRIKYNSSASTTYRAINTAFNIAYGSNSEEGPIA 163
Query: 171 ---YEDRIIVNKLA-TTQNFTFGVANEVPD-IFENYPVSGIFGLPXXXXXXXXXXXXVLS 225
++ + VN + +N F P+ F + GI GL
Sbjct: 164 LSGFQSQDTVNFAGYSIKNQIFAEITNAPETAFLKSQLDGILGLGFASIAI--------- 214
Query: 226 ESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLVEDLYTGDIHYASL 285
N+I+ ++L+ L ++ + S N G I+G LY+G + Y +
Sbjct: 215 --NSITPPFYNLMAQGLVNR-SVFSIYLNRNGTNAINGGELILGGSDSGLYSGCLTYVPV 271
Query: 286 ITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIRSGIVDSGTTLLILPTQ--DAL 343
+ YWQ + S +N G Q I+D GT+L+++P Q D +
Sbjct: 272 --SSAGYWQFTMTSANLN-------------GFQFCENCEAILDVGTSLIVVPEQVLDTI 316
Query: 344 DLHTFFVNSVSDGTNFAIPCNSTEILS---LEINGVKWPISSEEYLGEAYPQDSYYYGYC 400
+ +N + F + C+S L + K+P+ S +Y+ Y C
Sbjct: 317 NQILGVLNPTASNGVFLVDCSSIGDLPDIVFTVARRKFPLKSSDYV-------LRYGNTC 369
Query: 401 VSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
VS + + ILG +FL Y +D+ + GLA
Sbjct: 370 VSGFTSMNGNSLLILGEIFLGAYYTTYDIVYKLIGLA 406
>7300253 [O] KOG1339 Aspartyl protease
Length = 465
Score = 56.6 bits (135), Expect = 9e-08
Identities = 78/359 (21%), Positives = 137/359 (37%), Gaps = 48/359 (13%)
Query: 90 GMSILSTDSNTQAYFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXXXXXXXLF---- 143
G + L +N + Y + IG + + ++ D+GS+ +WV G +
Sbjct: 138 GTATLKNTANME-YTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCKSKACKKHKQYHPAK 196
Query: 144 STDNVKRAADESTFSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDI-FENYP 202
S+ VK +F++ Y SG+ +G + +D + + L T N TF + + P F
Sbjct: 197 SSTYVKNG---KSFAITYGSGSVAGVLAKDTVRIAGLVVT-NQTFAMTTKEPGTTFVTSN 252
Query: 203 VSGIFGLPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSAL---QAPL 259
GI GL +I+++ ++ + S+D TS A+
Sbjct: 253 FDGILGLGY----------------RSIAVDNVKTLVQNMCSEDVITSCKFAICMKGGGS 296
Query: 260 TENKGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQ 319
+ G I G Y+G Y + YWQ + +YV V+ S
Sbjct: 297 SSRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQDIYVGGTKVSGSV-------- 348
Query: 320 SSYIRSGIVDSGTTLLILPTQDALDLHTFF-VNSVSDGTNFAIPCNSTEILSLEINGVKW 378
IVDSGT+L+ PT ++ + S G + + I G K+
Sbjct: 349 -----QAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKCAKKIPDFTFVIAGKKF 403
Query: 379 PISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLA 437
+ + + + + C+S + + DE ILG F++ FD+ N + G A
Sbjct: 404 VVKGNKM--KLKVRTNRGRTVCISAVTEVP-DEPVILGDAFIRHFCTEFDLANNRIGFA 459
>CE21683 [O] KOG1339 Aspartyl protease
Length = 320
Score = 55.5 bits (132), Expect = 2e-07
Identities = 60/231 (25%), Positives = 91/231 (38%), Gaps = 26/231 (11%)
Query: 103 YFVNVTIGD--EIYPLVVDSGSAYLWVYGXXXXXXX-------XXXXXLFSTDNVKRAAD 153
Y N+++G + LV+D+GS+ LWV F T
Sbjct: 69 YLGNISVGTPGQTLTLVLDTGSSNLWVIDAACNSEACNGDPKSGFAKHKFDTKASSTFVS 128
Query: 154 EST-FSLIYSSGTASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGLPXX 212
E+ FS+ Y SG+ SG + D I + L N FGVA + +F PV GI GL
Sbjct: 129 ETRKFSISYGSGSCSGHLARDTITMGGLKI-DNQEFGVAETLASVFAEQPVDGILGL--- 184
Query: 213 XXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFIIGDLV 272
+ + M+ ++ L++K T D LQ N GL G L
Sbjct: 185 ------GWPALADDKVTPPMQN---LLPQLDAKVFTVWMDRKLQGSNGGNGGLITYGALD 235
Query: 273 EDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYI 323
DI Y L YW+ +D V S + T++ ++ + +S+I
Sbjct: 236 SVNCADDISYVPLTAKT--YWEFALDGFAVGSFS-ETKTAKVISDTGTSWI 283
>YLR121c [O] KOG1339 Aspartyl protease
Length = 508
Score = 53.5 bits (127), Expect = 7e-07
Identities = 90/405 (22%), Positives = 160/405 (39%), Gaps = 54/405 (13%)
Query: 98 SNTQAYF-VNVTIGDEIYPLVV--DSGSAYLWVYGXXX----XXXXXXXXXLF--STDNV 148
+N Q+++ V + IG L V D+GSA LWV G +F + +
Sbjct: 57 ANEQSFYSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSST 116
Query: 149 KRAADESTFSLIYSSGT-ASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIF 207
+A S F Y GT A G +D++ N+L + +F VANE F G+
Sbjct: 117 FKANKSSPFYAAYGDGTYAEGAFGQDKLKYNELDLS-GLSFAVANESNSTF------GVL 169
Query: 208 GLPXXXXXXXXXXXXVLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLTENKGLFI 267
G+ + + + + F L + + D T S +++ G +
Sbjct: 170 GIGLSTLEVTYSGKVAIMDKRSYEYDNFPLFLKHSGAIDATAY--SLFLNDESQSSGSIL 227
Query: 268 IGDLVEDLYTGDIHYASLIT---NENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYIR 324
G + Y G ++ L+ ++ + + D V Q + T + ++ +
Sbjct: 228 FGAVDHSKYEGQLYTIPLVNLYKSQGYQHPVAFD---VTLQGLGLQTDKRNITLTTTKLP 284
Query: 325 SGIVDSGTTLLILPTQDALDLHTFFVNSVSDGT--NFAIPCNSTE---ILSLEINGVKWP 379
+ ++DSGTTL LP+Q A+ L +N+ T + C S++ ++ + G +
Sbjct: 285 A-LLDSGTTLTYLPSQ-AVALLAKSLNASYSKTLGYYEYTCPSSDNKTSVAFDFGGFRIN 342
Query: 380 ISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFDVQNQQFGLANK 439
++ + G CV I + + ILG FL++ Y V+D+ N + LA
Sbjct: 343 APLSDFTMQTS------VGTCVLAIIPQAGNATAILGDSFLRNAYVVYDLDNYEISLAQA 396
Query: 440 N---------------ENAILVP-YVNSATNSSDTISGDRSSTTI 468
+AI P Y N+ +N + SG TT+
Sbjct: 397 KYGTGKENVEVIKSTVPSAIRAPSYNNTWSNYASATSGGNIFTTV 441
>YIL015w [O] KOG1339 Aspartyl protease
Length = 587
Score = 53.5 bits (127), Expect = 7e-07
Identities = 84/340 (24%), Positives = 134/340 (38%), Gaps = 65/340 (19%)
Query: 153 DESTFSLIYSSGT-ASGDVYEDRIIVNKLATTQNFTFGVANEVPDIFENYPVSGIFGLPX 211
+ F + Y+ GT A G + + +N + N FGVA + PVSG+ G+
Sbjct: 122 ENGRFYITYADGTFADGSWGTETVSINGI-DIPNIQFGVAK-----YATTPVSGVLGIGF 175
Query: 212 XXXXXXXXXXX-----------VLSESNAISMEKFSLIIGALNSKDNTTSEDSALQAPLT 260
+L I + +SL LNS D+ T
Sbjct: 176 PRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLF---LNSPDSGT----------- 221
Query: 261 ENKGLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAV------NFSTSEA 314
G + G + E ++GD+ ++ N Y + +D+ + + N S+ E
Sbjct: 222 ---GSIVFGAIDESKFSGDLFTFPMV---NEYPTI-VDAPATLAMTIQGLGAQNKSSCEH 274
Query: 315 VTGSQSSYIRSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIPCNSTEILSLEIN 374
T + + Y ++DSGT+LL P A + +F S S+ I + +E N
Sbjct: 275 ETFTTTKY--PVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYN 332
Query: 375 ------GVKWPISSEEYLGEAYPQDSYYYGYCVSNIQGLELDESWILGAVFLKDKYAVFD 428
+ P+SS E + Y G+ V ++S +LG VFL Y VFD
Sbjct: 333 FDFGDLQISVPLSSLILSPET---EGSYCGFAVQ-----PTNDSMVLGDVFLSSAYVVFD 384
Query: 429 VQNQQFGLANKNENA--ILVPYVNSATNSSDTISGDRSST 466
+ N + LA N NA + VN T+ S ISG + +T
Sbjct: 385 LDNYKISLAQANWNASEVSKKLVNIQTDGS--ISGAKIAT 422
>At2g36670 [O] KOG1339 Aspartyl protease
Length = 469
Score = 51.2 bits (121), Expect = 4e-06
Identities = 57/192 (29%), Positives = 99/192 (50%), Gaps = 33/192 (17%)
Query: 264 GLFIIGDLVEDLYTGDIHYASLITNENHYWQLKIDSVYVNSQAVNFSTSEAVTGSQSSYI 323
G+F++G++ L G + Y+ L+ ++ HY L + S+ VN Q + + ++S
Sbjct: 279 GVFVLGEI---LVPGMV-YSPLVPSQPHY-NLNLLSIGVNGQMLPLDAAVF----EASNT 329
Query: 324 RSGIVDSGTTLLILPTQDALDLHTFFVNSVSDGTNFAIP---CNSTE--ILSLEINGVKW 378
R IVD+GTTL L ++A DL F+N++S+ + + N + ++S I+ + +
Sbjct: 330 RGTIVDTGTTLTYL-VKEAYDL---FLNAISNSVSQLVTPIISNGEQCYLVSTSISDM-F 384
Query: 379 PISSEEYLGEAY----PQDS-YYYG-------YCVSNIQGLELDESWILGAVFLKDKYAV 426
P S + G A PQD ++YG +C+ + E E ILG + LKDK V
Sbjct: 385 PSVSLNFAGGASMMLRPQDYLFHYGIYDGASMWCIGFQKAPE--EQTILGDLVLKDKVFV 442
Query: 427 FDVQNQQFGLAN 438
+D+ Q+ G A+
Sbjct: 443 YDLARQRIGWAS 454
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.316 0.133 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,414,392
Number of Sequences: 60738
Number of extensions: 967219
Number of successful extensions: 2409
Number of sequences better than 1.0e-05: 32
Number of HSP's better than 0.0 without gapping: 0
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2354
Number of HSP's gapped (non-prelim): 44
length of query: 515
length of database: 30,389,216
effective HSP length: 111
effective length of query: 404
effective length of database: 23,647,298
effective search space: 9553508392
effective search space used: 9553508392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)