ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0575 good O KOG1357 Posttranslational modification, protein turnover, chaperones Serine palmitoyltransferase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0575 184033 182348 -562
(562 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YDR062w [O] KOG1357 Serine palmitoyltransferase 839 0.0
Hs4758668 [O] KOG1357 Serine palmitoyltransferase 427 e-119
CE27380 [O] KOG1357 Serine palmitoyltransferase 408 e-113
CE07246 [O] KOG1357 Serine palmitoyltransferase 408 e-113
At3g48780 [O] KOG1357 Serine palmitoyltransferase 401 e-111
At5g23670 [O] KOG1357 Serine palmitoyltransferase 400 e-111
7298232 [O] KOG1357 Serine palmitoyltransferase 389 e-108
CE13990 [O] KOG1357 Serine palmitoyltransferase 370 e-102
ECU05g0730 [O] KOG1357 Serine palmitoyltransferase 367 e-101
At3g48790 [O] KOG1357 Serine palmitoyltransferase 298 2e-80
7294669 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobu... 179 8e-45
SPAC21E11.08 [O] KOG1357 Serine palmitoyltransferase 166 7e-41
Hs7657118 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-keto... 161 2e-39
Hs5454084 [O] KOG1358 Serine palmitoyltransferase 159 1e-38
CE08323 [O] KOG1358 Serine palmitoyltransferase 154 4e-37
7303358 [O] KOG1358 Serine palmitoyltransferase 152 2e-36
SPBC18E5.02c [O] KOG1358 Serine palmitoyltransferase 148 2e-35
Hs4502025 [H] KOG1360 5-aminolevulinate synthase 136 1e-31
Hs4557299 [H] KOG1360 5-aminolevulinate synthase 135 2e-31
At4g36480 [O] KOG1358 Serine palmitoyltransferase 133 6e-31
YDR232w [H] KOG1360 5-aminolevulinate synthase 127 4e-29
YMR296c [O] KOG1358 Serine palmitoyltransferase 122 1e-27
7291697 [H] KOG1360 5-aminolevulinate synthase 120 4e-27
Hs20559517 [O] KOG1357 Serine palmitoyltransferase 117 4e-26
SPAC2F3.09 [H] KOG1360 5-aminolevulinate synthase 116 8e-26
At5g04620 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-keto... 110 6e-24
CE06500 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobu... 96 2e-19
Hs18597111 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ket... 92 2e-18
ECU02g0860 [O] KOG1358 Serine palmitoyltransferase 80 8e-15
>YDR062w [O] KOG1357 Serine palmitoyltransferase
Length = 561
Score = 839 bits (2167), Expect = 0.0
Identities = 405/554 (73%), Positives = 465/554 (83%), Gaps = 2/554 (0%)
Query: 7 TRVPLIPPEDIPLEDKKENEFGQLTSEEYLYQSKSRDGKALQDPILDAPAYHVSXXXXXX 66
TRVPL PE++P + +KENE+G L S +LYQ KSR GK L +P++D P Y++S
Sbjct: 8 TRVPLCEPEELPDDIQKENEYGTLDSPGHLYQVKSRHGKPLPEPVVDTPPYYISLLTYLN 67
Query: 67 XXXXXXXXXXXXXXXXTFQKEKHKDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTT 126
TFQK KH D++E DGLAPWFS FESFYVRR+K RIDDCFSRPTT
Sbjct: 68 YLILIILGHVHDFLGMTFQKNKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTT 127
Query: 127 GVPGRFIRCLDRVSHNLNDYFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYG 186
GVPGRFIRC+DR+SHN+N+YFTY G C+NLSSYNYLGFAQS+GQCT AALE+ DKY
Sbjct: 128 GVPGRFIRCIDRISHNINEYFTYSGAVYPCMNLSSYNYLGFAQSKGQCTDAALESVDKYS 187
Query: 187 VYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDS 246
+ SGGPR +IGTTDLH+ EK VA+F+GKEDA++FSMGYGTNAN FN+FLD KCLVISD
Sbjct: 188 IQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDE 247
Query: 247 LNHTSIRTGVRLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSM 306
LNHTSIRTGVRLSGAAV+TFKH DM LEKLIREQIV GQ KT+RPWKKI+IC EGL+SM
Sbjct: 248 LNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPWKKILICAEGLFSM 307
Query: 307 EGTMANLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKS 366
EGT+ NLPKLVELKKKYKCYLF+DEAHSIGAMGP+GRGVC+ FG+ D+DI+MGT TKS
Sbjct: 308 EGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKS 367
Query: 367 FGAAGGYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQ 426
FGAAGGYIAAD+WIIDR RLDLTT Y E PAPVLAQ SSL+TI+G+I PG+G ERLQ
Sbjct: 368 FGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPGQGTERLQ 427
Query: 427 RIAFNARYLRLALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPA 486
RIAFN+RYLRLALQRLGFIVYG+ADSPVIP+LLY PSKMPAFSRMMLQR+IAVVVVAYPA
Sbjct: 428 RIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPA 487
Query: 487 TPLIESRVRFCVSAALTKEDIDYLLQHINEVGDKLFLKVSSGKAGGSLDGKPPRWNIDEV 546
TPLIESRVRFC+SA+LTKEDIDYLL+H++EVGDKL LK +SGK+ S DGK RW+I+EV
Sbjct: 488 TPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKS--SYDGKRQRWDIEEV 545
Query: 547 IKRTPTDCKDDSFF 560
I+RTP DCKDD +F
Sbjct: 546 IRRTPEDCKDDKYF 559
>Hs4758668 [O] KOG1357 Serine palmitoyltransferase
Length = 562
Score = 427 bits (1099), Expect = e-119
Identities = 216/443 (48%), Positives = 294/443 (65%), Gaps = 1/443 (0%)
Query: 94 EQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTYPGTT 153
EQ + FE+FY R L RI D ++RP VPG + ++R SH+ N F Y G
Sbjct: 107 EQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNI 166
Query: 154 SM-CLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQF 212
+N+ SYNYLGFA++ G C AA + ++YG R IG D H E+ VA+F
Sbjct: 167 IKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARF 226
Query: 213 VGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMR 272
+G E A+ + MG+ TN+ + + CL++SD LNH S+ G RLSGA ++ FKHN+M+
Sbjct: 227 LGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQ 286
Query: 273 ALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEA 332
+LEKL+++ IV GQ +T RPWKKI+I VEG+YSMEG++ LP+++ LKKKYK YL++DEA
Sbjct: 287 SLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEA 346
Query: 333 HSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPH 392
HSIGA+GP+GRGV ++FG+ D+D+MMGT TKSFGA+GGYI K +ID R +
Sbjct: 347 HSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAV 406
Query: 393 YGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADS 452
Y PV+ QI +S+K I G G+E +Q++A N RY R L+ +GFI+YG DS
Sbjct: 407 YATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDS 466
Query: 453 PVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQ 512
PV+P++LY P+K+ AF R ML+R I VVVV +PATP+IESR RFC+SAA TKE +D L+
Sbjct: 467 PVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALK 526
Query: 513 HINEVGDKLFLKVSSGKAGGSLD 535
I+EVGD L LK S + LD
Sbjct: 527 EIDEVGDLLQLKYSRHRLVPLLD 549
>CE27380 [O] KOG1357 Serine palmitoyltransferase
Length = 586
Score = 408 bits (1049), Expect = e-113
Identities = 204/429 (47%), Positives = 279/429 (64%)
Query: 90 KDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTY 149
K+ + P FS FE+FY R ++ D F RP VPG + +DRVSH+ N + Y
Sbjct: 137 KENAKMKDFVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWTYEY 196
Query: 150 PGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYV 209
PGT + +N+ SYNYLGFAQS G C + + D+ G+ G + EK V
Sbjct: 197 PGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLV 256
Query: 210 AQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHN 269
A+F+G EDAI FSMG+ TN+ +D L+ISD NH S+ G RLSGA+ K F+HN
Sbjct: 257 AEFLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHN 316
Query: 270 DMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFV 329
DM +LE+++R+ I G KTHRP+KKI+I VEG+YSMEG++ NLP ++ LKKKY+ YL++
Sbjct: 317 DMESLERILRDAIAYGNPKTHRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYL 376
Query: 330 DEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLT 389
DEAHSIGAMG +G+GV +++G D+DI+MGT TKSFGAAGGYIA K +D R
Sbjct: 377 DEAHSIGAMGKTGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASP 436
Query: 390 TPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGI 449
T +Y P P+ QI +S+ I G +G +R++R+A N+ Y R+ L++ GFIVYG
Sbjct: 437 TGYYSSPMSPPIAQQIYTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGS 496
Query: 450 ADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDY 509
DSPV+PML+Y P+ + R ML R I VVV++PAT + E RVRFC+SAA TKE +D
Sbjct: 497 NDSPVVPMLIYFPTMCGFYGREMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDE 556
Query: 510 LLQHINEVG 518
+L+ +N +G
Sbjct: 557 VLETVNLLG 565
>CE07246 [O] KOG1357 Serine palmitoyltransferase
Length = 558
Score = 408 bits (1049), Expect = e-113
Identities = 204/429 (47%), Positives = 279/429 (64%)
Query: 90 KDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTY 149
K+ + P FS FE+FY R ++ D F RP VPG + +DRVSH+ N + Y
Sbjct: 109 KENAKMKDFVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWTYEY 168
Query: 150 PGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYV 209
PGT + +N+ SYNYLGFAQS G C + + D+ G+ G + EK V
Sbjct: 169 PGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLV 228
Query: 210 AQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHN 269
A+F+G EDAI FSMG+ TN+ +D L+ISD NH S+ G RLSGA+ K F+HN
Sbjct: 229 AEFLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHN 288
Query: 270 DMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFV 329
DM +LE+++R+ I G KTHRP+KKI+I VEG+YSMEG++ NLP ++ LKKKY+ YL++
Sbjct: 289 DMESLERILRDAIAYGNPKTHRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYL 348
Query: 330 DEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLT 389
DEAHSIGAMG +G+GV +++G D+DI+MGT TKSFGAAGGYIA K +D R
Sbjct: 349 DEAHSIGAMGKTGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASP 408
Query: 390 TPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGI 449
T +Y P P+ QI +S+ I G +G +R++R+A N+ Y R+ L++ GFIVYG
Sbjct: 409 TGYYSSPMSPPIAQQIYTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGS 468
Query: 450 ADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDY 509
DSPV+PML+Y P+ + R ML R I VVV++PAT + E RVRFC+SAA TKE +D
Sbjct: 469 NDSPVVPMLIYFPTMCGFYGREMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDE 528
Query: 510 LLQHINEVG 518
+L+ +N +G
Sbjct: 529 VLETVNLLG 537
>At3g48780 [O] KOG1357 Serine palmitoyltransferase
Length = 489
Score = 401 bits (1031), Expect = e-111
Identities = 201/428 (46%), Positives = 274/428 (63%)
Query: 97 GLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTYPGTTSMC 156
G AP E FY+RRL RI DCF RP + P +I ++RVS + N TS C
Sbjct: 43 GYAPICLAHEDFYIRRLYHRIQDCFGRPISSAPDAWIDVVERVSDDNNKTLKRTTKTSRC 102
Query: 157 LNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKE 216
LNL SYNYLGF + CT +E+ K+ + R GTT +H E VA++VG+
Sbjct: 103 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSASTCSSRVDAGTTSVHAELEDCVAKYVGQP 162
Query: 217 DAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEK 276
A++F MGY TN+ + L+ISDSLNHTSI G R SGA ++ F+HN LEK
Sbjct: 163 AAVIFGMGYATNSAIIPVLIGKGGLIISDSLNHTSIVNGARGSGATIRVFQHNTPGHLEK 222
Query: 277 LIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIG 336
+++EQI +GQ +THRPWKKII+ VEG+YSMEG + +LP++V + KKYK Y+++DEAHSIG
Sbjct: 223 VLKEQIAEGQPRTHRPWKKIIVVVEGIYSMEGEICHLPEIVSICKKYKAYVYLDEAHSIG 282
Query: 337 AMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEP 396
A+G +GRGVC+ G+ SD+DIMMGT TKSFG+ GGYIA K +I + Y
Sbjct: 283 AIGKTGRGVCELLGVDTSDVDIMMGTFTKSFGSCGGYIAGSKDLIQYLKHQCPAHLYATS 342
Query: 397 TPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIP 456
P QI S++K I G+ G ++L RI N+ + R LQ++GF V G DSPV+P
Sbjct: 343 ISTPSATQIISAIKVILGEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMP 402
Query: 457 MLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINE 516
++LY P+K+PAFSR L+ +AVVVV +PATPL+ +R R C+SA+ ++ED+ LQ I++
Sbjct: 403 IMLYNPAKIPAFSRECLRENLAVVVVGFPATPLLLARARICISASHSREDLIKALQVISK 462
Query: 517 VGDKLFLK 524
GD +K
Sbjct: 463 AGDLTGIK 470
>At5g23670 [O] KOG1357 Serine palmitoyltransferase
Length = 489
Score = 400 bits (1027), Expect = e-111
Identities = 196/423 (46%), Positives = 275/423 (64%)
Query: 97 GLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTYPGTTSMC 156
G AP E FY+RRL RI DCF RP + P + ++R S++ N TS C
Sbjct: 43 GYAPICLGHEDFYIRRLYHRIQDCFERPISSAPDAWFDVVERYSNDNNKTLKRTTKTSRC 102
Query: 157 LNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKE 216
LNL SYNYLGF + CT +E+ K+ + R GTT +H E+ V +FVGK
Sbjct: 103 LNLGSYNYLGFGSFDEYCTPRVIESLKKFSASTCSSRVDAGTTSVHAELEECVTRFVGKP 162
Query: 217 DAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEK 276
A++F MGY TN+ + L+ISDSLNH+SI G R SGA ++ F+HN LE+
Sbjct: 163 AAVVFGMGYATNSAIIPVLIGKGGLIISDSLNHSSIVNGARGSGATIRVFQHNTPSHLER 222
Query: 277 LIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIG 336
++REQI +GQ +THRPWKKII+ VEG+YSMEG + +LP++V + KKYK Y+++DEAHSIG
Sbjct: 223 VLREQIAEGQPRTHRPWKKIIVVVEGIYSMEGEICHLPEVVAICKKYKAYVYLDEAHSIG 282
Query: 337 AMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEP 396
A+G +G+G+C+ G+ +D+D+MMGT TKSFG+ GGYIA K +I + Y
Sbjct: 283 AIGKTGKGICELLGVDTADVDVMMGTFTKSFGSCGGYIAGSKELIQYLKHQCPAHLYATS 342
Query: 397 TPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIP 456
P P QI S++K I G+ G ++L RI N+ + R LQ++GF V G DSPV+P
Sbjct: 343 IPTPSAQQIISAIKVILGEDGSNRGAQKLARIRENSNFFRAELQKMGFEVLGDNDSPVMP 402
Query: 457 MLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINE 516
++LY P+K+PAFSR L++K+AVVVV +PATPL+ +R R C+SA+ ++ED+ L+ I++
Sbjct: 403 IMLYNPAKIPAFSRECLRQKVAVVVVGFPATPLLLARARICISASHSREDLIRALKVISK 462
Query: 517 VGD 519
VGD
Sbjct: 463 VGD 465
>7298232 [O] KOG1357 Serine palmitoyltransferase
Length = 597
Score = 389 bits (998), Expect = e-108
Identities = 200/433 (46%), Positives = 275/433 (63%), Gaps = 1/433 (0%)
Query: 95 QDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTYPGTTS 154
+DG + FESFY R + +RI DC++RP VPG + DRV+ + F + GT +
Sbjct: 154 RDGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTGTET 213
Query: 155 MCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVG 214
CLNL SYNYLGFA + GQC + E+ G+ R +G + E A++ G
Sbjct: 214 RCLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFG 273
Query: 215 KEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRAL 274
EDAI+F MG+ TNA S L LVISD NH SI G+RLSGA K FKHN+MR L
Sbjct: 274 VEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDL 333
Query: 275 EKLIREQIVQGQSKTH-RPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAH 333
E+++R+ + G K +PW K++I VEG++SMEG++ LP+++ LKKKYK YL++DEAH
Sbjct: 334 ERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAH 393
Query: 334 SIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHY 393
S+GAMG GRGV D+F + ++DI+MGT TKSFG+AGGY+A K +ID R + Y
Sbjct: 394 SVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCY 453
Query: 394 GEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSP 453
P+ QI +S+KTI G+ G++++ ++A N RY R L +LG I YG DSP
Sbjct: 454 AASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSP 513
Query: 454 VIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQH 513
V+PML+Y SK+ A R + R IA V +PATP++E R+RFC+SAA TKE +D+ L+
Sbjct: 514 VVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEA 573
Query: 514 INEVGDKLFLKVS 526
I+E+ D L LK S
Sbjct: 574 IDEIADDLGLKYS 586
>CE13990 [O] KOG1357 Serine palmitoyltransferase
Length = 527
Score = 370 bits (950), Expect = e-102
Identities = 189/447 (42%), Positives = 272/447 (60%), Gaps = 15/447 (3%)
Query: 87 EKHKDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVS--HNLN 144
++ K + P ++F++ Y + ++ D +RP +GVPG +R DR + H
Sbjct: 67 KRSKGDPRMESFQPLGNSFDATYTDHIYRQSTDVVNRPISGVPGAIVRLKDRYTDDHGWT 126
Query: 145 D-------------YFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGG 191
+++Y GT S +NL SYNYLGF+ G C AA DKYG+ GG
Sbjct: 127 QKLVIERASQLEYIFWSYTGTESEVINLGSYNYLGFSHRSGVCAEAAAAHIDKYGINCGG 186
Query: 192 PRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTS 251
R IG H E +AQ++ EDAI+F MG+ TN+ S +D L++SD LNH S
Sbjct: 187 SRQEIGNHVAHKSVESTIAQYLNVEDAIVFPMGFATNSMNIPSLVDKGSLILSDRLNHAS 246
Query: 252 IRTGVRLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMA 311
+ TG RLSGA F+HND E+ +R+ + KT + K++I +EG+YSMEGT+
Sbjct: 247 LVTGCRLSGAHTVVFRHNDASDCERKLRDALCGVSPKTGEKYNKVLIIIEGIYSMEGTIV 306
Query: 312 NLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAG 371
NLP + +KKKY CYLF+DEAHSIGA+GPSGRGV +++G DIDIMMGTLTKSF +AG
Sbjct: 307 NLPAFIAVKKKYNCYLFLDEAHSIGAVGPSGRGVAEYWGCNPRDIDIMMGTLTKSFASAG 366
Query: 372 GYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFN 431
GY+ K +ID R YG P++AQ+ ++ ++G G+++ ++ N
Sbjct: 367 GYMGGSKKVIDHIRRYSAGTCYGVTMSPPLIAQVERAVLIMSGKDGTDIGRQKAIQLLEN 426
Query: 432 ARYLRLALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIE 491
+RY R L++ GF+VYG DSPV+P++ + +K+ FSR ML+ I +V V YPATPL+E
Sbjct: 427 SRYFRKELRKRGFLVYGNNDSPVVPLMTFYITKVVEFSRRMLKHNIGIVAVGYPATPLLE 486
Query: 492 SRVRFCVSAALTKEDIDYLLQHINEVG 518
+RVRFC+SA TKE +DY+L+ + +VG
Sbjct: 487 ARVRFCLSADHTKEHLDYILEAVEQVG 513
>ECU05g0730 [O] KOG1357 Serine palmitoyltransferase
Length = 475
Score = 367 bits (942), Expect = e-101
Identities = 186/442 (42%), Positives = 275/442 (62%), Gaps = 3/442 (0%)
Query: 84 FQKEKHKDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNL 143
F + +K +G P +S+FESF+ RR+ +R+ DC+ RP GVPGR + ++R+S +
Sbjct: 35 FFPKVYKKYKLDNGKPPLYSSFESFFSRRIFRRVRDCWERPIVGVPGRHVTVMERISDDY 94
Query: 144 NDYFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHV 203
N+ F G LN SYNYLGF+ ++G ++A +Y + P +G D+
Sbjct: 95 NESFRLTGRRLKLLNFGSYNYLGFSSNKGPVVEKVVKAVYRYPLVLAAPAREVGCYDIAR 154
Query: 204 MTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAV 263
E+ +A F+ +ED ++FSMGYGTN++ + + L++SD LNH S+ TG ++S +
Sbjct: 155 ELEEEMASFLHQEDCMVFSMGYGTNSSNIPVICEEETLILSDELNHASLITGAKISRGVI 214
Query: 264 KTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKY 323
+ F+HN+M LE+ + I QGQ THR WKKII+ VEG+YSMEGT+ L +LVELK+KY
Sbjct: 215 RVFEHNNMEDLERKLVFNISQGQPLTHRAWKKIIVIVEGIYSMEGTVVKLRRLVELKRKY 274
Query: 324 KCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDR 383
K Y+FVDEAHSIGA+G +GRGVC+ G+ +++DI+MGT TKSFG GGYIA + +I
Sbjct: 275 KFYIFVDEAHSIGALGATGRGVCEHTGVDFTEVDILMGTFTKSFGGMGGYIAGSRKLITW 334
Query: 384 FRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLG 443
R YG+ P V +Q+ SL+ I G+ +++++ N +R +L G
Sbjct: 335 LRFYSDMSLYGDQLPPLVCSQVLESLRCIK---FTELGRMKIEKLRSNTVLMRQSLVSAG 391
Query: 444 FIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALT 503
F V G SPVIP+L+ P K+ FSR + I VVVV YPATP++ SR R CVSA+ T
Sbjct: 392 FFVLGDEFSPVIPVLILCPGKVAEFSRRCMSEGIGVVVVGYPATPILTSRARLCVSASHT 451
Query: 504 KEDIDYLLQHINEVGDKLFLKV 525
ED+ + I+ +G++L +K+
Sbjct: 452 TEDVMRAFEVIDRIGEELGMKI 473
>At3g48790 [O] KOG1357 Serine palmitoyltransferase
Length = 350
Score = 298 bits (762), Expect = 2e-80
Identities = 147/328 (44%), Positives = 215/328 (64%), Gaps = 7/328 (2%)
Query: 197 GTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGV 256
GTT +H E+ VA+FVGK A++F MGY TN+ + + L+ISDSLNHTSI G
Sbjct: 7 GTTAVHGELEECVAKFVGKPAAVVFGMGYLTNSAIISVLIGKGGLIISDSLNHTSIINGA 66
Query: 257 RLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKL 316
R SGA ++ F+HN +++E I++GQ +THRPWKKII+ VEG+YSMEG + +LP++
Sbjct: 67 RGSGATIRVFQHN-------ILKEHIIEGQPRTHRPWKKIIVVVEGIYSMEGEICDLPEI 119
Query: 317 VELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAA 376
V + +YK Y+++DEAHSIGA+G +GRGVC+ G+ +++DIMMGT TKS G+ GGYIA
Sbjct: 120 VSVCSEYKAYVYLDEAHSIGAIGKTGRGVCELLGVDTTEVDIMMGTFTKSLGSCGGYIAG 179
Query: 377 DKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLR 436
K ++ + Y P Q+ S++K I G G+ +L RI N+ + R
Sbjct: 180 SKDLVQYLKQHYPAHLYATSISTPAAQQVISAIKVIFGVDGSNRGELKLARIRENSNFFR 239
Query: 437 LALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRF 496
LQ++GF V G+ DSP++P++LY P+K+ AFSR L+ +A+VVV++P PL+ +R R
Sbjct: 240 AELQKMGFKVLGVYDSPIMPIMLYNPAKIAAFSRECLRENLAIVVVSFPPIPLLLARARI 299
Query: 497 CVSAALTKEDIDYLLQHINEVGDKLFLK 524
C SA+ +ED+ LQ I+ GD +K
Sbjct: 300 CNSASHLREDLIKALQVISRAGDLTGIK 327
>7294669 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobutyrate-CoA
ligase
Length = 404
Score = 179 bits (455), Expect = 8e-45
Identities = 122/384 (31%), Positives = 196/384 (50%), Gaps = 20/384 (5%)
Query: 139 VSHNLNDYFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGT 198
++ + + T G+ LN + NYLG A + + + + ++YG R GT
Sbjct: 36 ITSSQSTQITVQGSDKKILNFCANNYLGLANNP-EIVEHSQKLLEQYGAGLSSVRFICGT 94
Query: 199 TDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRL 258
D+H EK +AQF G+ED IL++ + NA F + L + V SD LNH SI G+RL
Sbjct: 95 QDIHKQLEKKIAQFHGREDTILYASCFDANAGIFEAILTPEDAVFSDELNHASIIDGIRL 154
Query: 259 SGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVE 318
A + ++H D+ LE EQ+ ++ +I +G++SM+G +A L ++VE
Sbjct: 155 CKAKKQRYRHRDLGDLE----EQLKASDARLK------LIATDGVFSMDGNIAPLARIVE 204
Query: 319 LKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSF-GAAGGYIAAD 377
L +KY +FVDE H+ G G +GRG ++ + ++DI+ TL K+ GA+GGY
Sbjct: 205 LARKYNALVFVDECHATGFFGATGRGTEEYDNV-MGEVDIINSTLGKALGGASGGYTTGP 263
Query: 378 KWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRL 437
+I F + P+ T P A +A LK + + + E QR+ N + R
Sbjct: 264 AELIS-FLRQKSRPYLFSNTLPP--AVVAVGLKVMDMLL---QSSELTQRVQSNTQRFRQ 317
Query: 438 ALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFC 497
A+ + GF + G + P+ P++L F+ ML R I V+ +YP P ++R+R
Sbjct: 318 AMTKAGFTIAG-ENHPICPVMLGDARLASQFADEMLTRGIYVIGFSYPVVPQGKARIRVQ 376
Query: 498 VSAALTKEDIDYLLQHINEVGDKL 521
+SAA T+ +ID + EVG L
Sbjct: 377 ISAAHTEAEIDRAINAFIEVGRSL 400
>SPAC21E11.08 [O] KOG1357 Serine palmitoyltransferase
Length = 272
Score = 166 bits (421), Expect = 7e-41
Identities = 91/225 (40%), Positives = 122/225 (53%), Gaps = 1/225 (0%)
Query: 12 IPPEDIPLEDKKENEFGQLTSEEYLYQSKSRDGKALQDPILDAPAYHVSXXXXXXXXXXX 71
+ E + E ENEF +T + SK+ DG L D P+Y+
Sbjct: 46 VAAEKLNSEHLLENEFAPITDPTHRRVSKNPDGAELFQ-FEDEPSYYYVVATYLTYLVLI 104
Query: 72 XXXXXXXXXXXTFQKEKHKDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGR 131
F K+ +K + + DG AP ++ F++FYVRRL+ RI+DCFSRPT GVPGR
Sbjct: 105 IIGHVRDFFGKRFHKDDYKYLKDNDGYAPLYNHFDNFYVRRLQHRINDCFSRPTMGVPGR 164
Query: 132 FIRCLDRVSHNLNDYFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGG 191
IR ++R S + N F G TS+ LN+SSYNYLGFAQS G C T EA KYG+ +
Sbjct: 165 VIRLMNRYSTDSNSTFKLTGDTSLALNVSSYNYLGFAQSHGPCATKVEEAMQKYGLSTCS 224
Query: 192 PRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFL 236
GT LH E+ A FVGK A++FS G+ TNA F++ +
Sbjct: 225 SNAICGTYGLHKEVEELTANFVGKPAALVFSQGFSTNATVFSTLM 269
>Hs7657118 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobutyrate-CoA
ligase
Length = 419
Score = 161 bits (408), Expect = 2e-39
Identities = 111/369 (30%), Positives = 182/369 (49%), Gaps = 19/369 (5%)
Query: 151 GTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVA 210
G + LN + NYLG + S + A L+A +++G R GT +H E +A
Sbjct: 62 GVSGGILNFCANNYLGLS-SHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIA 120
Query: 211 QFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHND 270
+F +EDAIL+ Y NA F + L + V+SD LNH SI G+RL A ++H D
Sbjct: 121 RFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLD 180
Query: 271 MRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVD 330
M LE ++E ++ HR ++ +G +SM+G +A L ++ L +Y +F+D
Sbjct: 181 MADLEAKLQE------AQKHR---LRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMD 231
Query: 331 EAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSF-GAAGGYIAADKWIIDRFRLDLT 389
E H+ G +GP+GRG + G+ + I+ TL K+ GA+GGY ++ R
Sbjct: 232 ECHATGFLGPTGRGTDELLGV-MDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRAR 290
Query: 390 TPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGI 449
+ P V+ + +L + G +Q +A + R ++ GF + G
Sbjct: 291 PYLFSNSLPPAVVGCASKALDLLMG------SNTIVQSMAAKTQRFRSKMEAAGFTISG- 343
Query: 450 ADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDY 509
A P+ P++L + ML+R I V+ +YP P ++R+R +SA ++EDID
Sbjct: 344 ASHPICPVMLGDARLASRMADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDR 403
Query: 510 LLQHINEVG 518
++ EVG
Sbjct: 404 CVEAFVEVG 412
>Hs5454084 [O] KOG1358 Serine palmitoyltransferase
Length = 473
Score = 159 bits (402), Expect = 1e-38
Identities = 118/381 (30%), Positives = 189/381 (48%), Gaps = 20/381 (5%)
Query: 156 CLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGK 215
C+N +S+N+LG + + AAL + KYGV + GPR GT D+H+ E +A+F+
Sbjct: 100 CINFASFNFLGLLDNP-RVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKT 158
Query: 216 EDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALE 275
E+AI++S G+ T A+ ++ +V D +I+ G++ S + +K FKHNDM LE
Sbjct: 159 EEAIIYSYGFATIASAIPAYSKRGDIVFVDRAACFAIQKGLQASRSDIKLFKHNDMADLE 218
Query: 276 KLIREQIVQGQSKTHRP-WKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHS 334
+L++EQ ++ Q + + I VEGLY GT+ LP+LV+LK KYK +F++E+ S
Sbjct: 219 RLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIFLEESLS 278
Query: 335 IGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYG 394
G +G GRGV + +GI DID++ + + + GG+ ++ID RL +
Sbjct: 279 FGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFS 338
Query: 395 EPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRL-GFIVYGIADSP 453
P P+LA A I + NPG ++ + ALQ + G V G + SP
Sbjct: 339 ASLP-PLLAAAAIEALNIMEE-NPGIFAVLKEKCG----QIHKALQGISGLKVVGESLSP 392
Query: 454 VIPMLLYAPSKMPAFSRMMLQ--------RKIAVVVVAY---PATPLIESRVRFCVSAAL 502
+ L + +LQ R IA+ Y L +R V+
Sbjct: 393 AFHLQLEESTGSREQDVRLLQEIVDQCMNRSIALTQARYLEKEEKCLPPPSIRVVVTVEQ 452
Query: 503 TKEDIDYLLQHINEVGDKLFL 523
T+E+++ I EV + L
Sbjct: 453 TEEELERAASTIKEVAQAVLL 473
>CE08323 [O] KOG1358 Serine palmitoyltransferase
Length = 458
Score = 154 bits (388), Expect = 4e-37
Identities = 98/300 (32%), Positives = 162/300 (53%), Gaps = 6/300 (2%)
Query: 157 LNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKE 216
LN++S N+L F + + A + KYGV S GPR GT D+H+ EK +A+F+G E
Sbjct: 89 LNMASTNFLSFIGVK-RIEDRAKQTIFKYGVGSCGPRGFYGTVDVHLDLEKELAKFMGCE 147
Query: 217 DAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEK 276
+A+L+S G+ T ++ ++ ++ D + +I+ G++ S + V+ FKHNDM LE+
Sbjct: 148 EAVLYSYGFATVSSAIPAYAKKGDVIFVDEGVNFAIQKGLQASRSRVEYFKHNDMEHLER 207
Query: 277 LIREQIVQGQSKTHRPWKKI--IICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHS 334
L+ EQ Q K + K + I VEGLY + LPK++E K ++K +F+DE+ S
Sbjct: 208 LLLEQ-EQRDKKDPKKAKSVRRFIVVEGLYVNYADLCPLPKIIEFKWRFKVRVFIDESWS 266
Query: 335 IGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYG 394
G +G +GRGV + F +P D+D++M +L + + GG+ +++ RL +
Sbjct: 267 FGVIGKTGRGVTEHFNVPMEDVDMVMASLENALASTGGFCVGRSYVVGHQRLSGLGYCFS 326
Query: 395 EPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPV 454
P P+LA AS +I D P Q+ + + L+ AL F + G +SP+
Sbjct: 327 ASLP-PLLATAASEAISII-DEEPSRVQKVTEMAINGQKKLQDALSGSKFSLQGCPESPM 384
>7303358 [O] KOG1358 Serine palmitoyltransferase
Length = 468
Score = 152 bits (383), Expect = 2e-36
Identities = 112/379 (29%), Positives = 184/379 (47%), Gaps = 20/379 (5%)
Query: 156 CLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGK 215
CLNL S+NYLGF + + + A ++ KYGV S GPR GT D+H+ E +A+F+G
Sbjct: 96 CLNLGSHNYLGFLEDQ-EILEEACKSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGL 154
Query: 216 EDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALE 275
E+AI++S G+ T A+ ++ L+ D + +I+ G+ S + + FKHND+ LE
Sbjct: 155 EEAIVYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLE 214
Query: 276 KLIREQIVQGQSKTHRPWK-KIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHS 334
+L+ EQ + Q + K + + EG+Y G + LP LV L++KYK LF+DE+ S
Sbjct: 215 RLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESIS 274
Query: 335 IGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYG 394
G +G G GV + F + ++D++ + S GG+ +I + RL +
Sbjct: 275 FGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFS 334
Query: 395 EPTPAPVLAQIA-SSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSP 453
P P+L Q A S+L + E Q + + + ++LR + L G SP
Sbjct: 335 ASLP-PMLTQAAISALDRFEREPQIFE-QLQAKSKTLHQKFLRFSKLTL----RGDEVSP 388
Query: 454 VIPMLLYAPSK--------MPAFSRMMLQRKIAVVVVAY---PATPLIESRVRFCVSAAL 502
V + L P++ + + + R +AVV AY + +R V+ L
Sbjct: 389 VKHLYLAQPAENFDKELKLLTELADKCIARGVAVVQAAYLQNRERQPVRPSIRIAVNRLL 448
Query: 503 TKEDIDYLLQHINEVGDKL 521
+ID + I V +
Sbjct: 449 ESSEIDNAFEVIESVSSSV 467
>SPBC18E5.02c [O] KOG1358 Serine palmitoyltransferase
Length = 509
Score = 148 bits (374), Expect = 2e-35
Identities = 103/379 (27%), Positives = 188/379 (49%), Gaps = 19/379 (5%)
Query: 158 NLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKED 217
N +S+N+L A+++ T A+ + G+ + GP GT D H+ EK +A F+G E
Sbjct: 131 NFASFNFLDLAENK-HITECAVATLRECGLGACGPPGFYGTQDKHLRLEKDIASFIGVER 189
Query: 218 AILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKL 277
AI+++ + T ++ +F +++ D + +I+ G+++S ++ FKHN+M+ LE++
Sbjct: 190 AIVYAQSFQTISSVIPAFSKRGDILVVDEACNFAIQKGIQISRTTIRYFKHNNMKDLERI 249
Query: 278 IREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGA 337
++E + K +RP + I EG+ G M +L K+V LKKKYK L +DE S G
Sbjct: 250 LQE-LEDDFVKHNRPLTRRFIITEGISENYGDMVDLTKIVALKKKYKYRLILDETWSFGT 308
Query: 338 MGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPT 397
G +G+G+ + FG+P +D++I++G+LT S GG+ A + +++ RL Y
Sbjct: 309 CGRTGKGLTEHFGVPPTDVEIIIGSLTTSLAGGGGFCAGSELMVEHQRLSGMAYIYSAAL 368
Query: 398 PAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPM 457
PA + ++ ++ D R + F+A+ R F +SP+I
Sbjct: 369 PASLAVAAYEAISILSRDGGSMLNDLRSKSALFHAKLSRNKF----FETSSDIESPII-H 423
Query: 458 LLYAPSKMPAFSRMMLQRKIAVVVVA----YPATPLIES--------RVRFCVSAALTKE 505
L + + ++ L +I + +A +ES +R C+S + E
Sbjct: 424 LRFKDKDISHDKQVFLLEEIVELCIAEGFLIARAKRVESLERVKVQPSLRICISTGHSAE 483
Query: 506 DIDYLLQHINEVGDKLFLK 524
+I+ L I E + +F K
Sbjct: 484 EIEKLALLIKEKTEIVFDK 502
>Hs4502025 [H] KOG1360 5-aminolevulinate synthase
Length = 640
Score = 136 bits (342), Expect = 1e-31
Identities = 119/436 (27%), Positives = 201/436 (45%), Gaps = 28/436 (6%)
Query: 85 QKEKHKDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNL- 143
Q+ + + QD L STF+ Y R +++ID+ + T R + ++R +H
Sbjct: 177 QRPERVSHLLQDNLPKSVSTFQ--YDRFFEKKIDEKKNDHTY----RVFKTVNRRAHIFP 230
Query: 144 --NDYFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDL 201
+DY T S +YLG ++ C A ++ ++G +GG R GT+
Sbjct: 231 MADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCG-AVMDTLKQHGAGAGGTRNISGTSKF 289
Query: 202 HVMTEKYVAQFVGKEDAILFSMGYGTNAN--FFNSFLDSKCLVISDSLNHTSIRTGVRLS 259
HV E+ +A GK+ A+LFS + N + F + + C + SDS NH S+ G+R S
Sbjct: 290 HVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNS 349
Query: 260 GAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVEL 319
F+HND+ L +L++ P I+ E ++SM+G + L +L ++
Sbjct: 350 RVPKYIFRHNDVSHLRELLQRS---------DPSVPKIVAFETVHSMDGAVCPLEELCDV 400
Query: 320 KKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKW 379
++ FVDE H++G G G G+ D G+ +DI+ GTL K+FG GGYIA+
Sbjct: 401 AHEFGAITFVDEVHAVGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIASTSS 459
Query: 380 IIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLAL 439
+ID R + P +LA S++ + EG+ ++ N + +R L
Sbjct: 460 LIDTVRSYAAGFIFTTSLPPMLLAGALESVRI----LKSAEGRVLRRQHQRNVKLMRQML 515
Query: 440 QRLGFIVYGIADSPVIPM-LLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCV 498
G V S +IP+ + A +M + I V + YP P E +R
Sbjct: 516 MDAGLPVVH-CPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEELLRIAP 574
Query: 499 SAALTKEDIDYLLQHI 514
+ T + ++Y L+++
Sbjct: 575 TPHHTPQMMNYFLENL 590
>Hs4557299 [H] KOG1360 5-aminolevulinate synthase
Length = 587
Score = 135 bits (339), Expect = 2e-31
Identities = 104/342 (30%), Positives = 166/342 (48%), Gaps = 19/342 (5%)
Query: 161 SYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAIL 220
S +YLG ++ Q A E ++G +GG R GT+ HV E+ +A+ K+ A+L
Sbjct: 196 SNDYLGMSRHP-QVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALL 254
Query: 221 FSMGYGTNAN--FFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKLI 278
FS + N + F + + C + SD+ NH S+ G+R SGAA F+HND L+KL+
Sbjct: 255 FSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL 314
Query: 279 REQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAM 338
+ P I+ E ++SM+G + L +L ++ +Y FVDE H++G
Sbjct: 315 EKS---------NPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLY 365
Query: 339 GPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPTP 398
G G G+ + GI IDI+ GTL K+FG GGYIA+ + ++D R + P
Sbjct: 366 GSRGAGIGERDGI-MHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLP 424
Query: 399 APVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPML 458
VL+ S++ + G+ EGQ + N +++R L G V S +IP+
Sbjct: 425 PMVLSGALESVRLLKGE----EGQALRRAHQRNVKHMRQLLMDRGLPVIP-CPSHIIPIR 479
Query: 459 LYAPSKMPAFSRMMLQRK-IAVVVVAYPATPLIESRVRFCVS 499
+ + ++L + I V + YP P E +R S
Sbjct: 480 VGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPS 521
>At4g36480 [O] KOG1358 Serine palmitoyltransferase
Length = 475
Score = 133 bits (335), Expect = 6e-31
Identities = 84/266 (31%), Positives = 141/266 (52%), Gaps = 8/266 (3%)
Query: 157 LNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKE 216
+N +S NYLG E + + A +KYGV S GPR GT D+H+ E +++F+G
Sbjct: 112 VNFASANYLGLIGHE-KLLESCTSALEKYGVGSCGPRGFYGTIDVHLDCETRISKFLGTP 170
Query: 217 DAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEK 276
D+IL+S G T + F ++++D H I+ G++LS + + FKHNDM +L +
Sbjct: 171 DSILYSYGLSTMFSTIPCFCKKGDVIVADEGVHWGIQNGLQLSRSTIVYFKHNDMESL-R 229
Query: 277 LIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIG 336
+ E+I+ ++ + I+ E +Y G +A L ++V+LK+KY+ + +DE++S G
Sbjct: 230 ITLEKIMTKYKRSKNLRRYIV--AEAVYQNSGQIAPLDEIVKLKEKYRFRVILDESNSFG 287
Query: 337 AMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEP 396
+G SGRG+ + +P ID++ + + GG+ + IID RL + +
Sbjct: 288 VLGRSGRGLAEHHSVPIEKIDVVTAAMGHALATEGGFCTGNARIIDYQRLSSSGYVFSAS 347
Query: 397 TPAPVLAQIASSLKTI---TGDINPG 419
P P LA A + + DIN G
Sbjct: 348 LP-PYLASAAITAIDVIDQNPDINAG 372
>YDR232w [H] KOG1360 5-aminolevulinate synthase
Length = 548
Score = 127 bits (319), Expect = 4e-29
Identities = 114/402 (28%), Positives = 185/402 (45%), Gaps = 44/402 (10%)
Query: 161 SYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAIL 220
S +YL ++ + A + DKYG +GG R G + E +A KE A++
Sbjct: 120 SNDYLALSKHP-EVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALV 178
Query: 221 FSMGYGTNANFFNSFLDSKC---LVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKL 277
FS Y N S L K ++ SD LNH S+ G++ + FKHND+ LE
Sbjct: 179 FSSCYVANDAVL-SLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELE-- 235
Query: 278 IREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGA 337
Q++Q K+ +I E +YSM G++A++ K+ +L KY F+DE H++G
Sbjct: 236 ---QLLQSYPKSVPK----LIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGL 288
Query: 338 MGPSGRGV---CDFFGIPCSDI------------------DIMMGTLTKSFGAAGGYIAA 376
GP G GV CDF S I D++ GTL KSFG+ GGY+AA
Sbjct: 289 YGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAA 348
Query: 377 DKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLR 436
+ +ID FR + P V+A ++++ I+ Q++ + Y++
Sbjct: 349 SRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQK------HTMYVK 402
Query: 437 LALQRLGFIVYGIADSPVIPMLL-YAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVR 495
A LG V S ++P+L+ A A ++ + +I V + +P R+R
Sbjct: 403 KAFHELGIPVIP-NPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLR 461
Query: 496 FCVSAALTKEDIDYLLQHINEVGDKLFL-KVSSGKAGGSLDG 536
+ T + D L+ +++V ++L L +V ++ G L G
Sbjct: 462 ITPTPGHTNDLSDILINAVDDVFNELQLPRVRDWESQGGLLG 503
>YMR296c [O] KOG1358 Serine palmitoyltransferase
Length = 558
Score = 122 bits (306), Expect = 1e-27
Identities = 77/272 (28%), Positives = 138/272 (50%), Gaps = 4/272 (1%)
Query: 158 NLSSYNYLGFAQSEGQCTTAALEATDK-YGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKE 216
NL+S N+L + +E ++ T K YGV + GP G D+H E +AQF G +
Sbjct: 149 NLASNNFLQLSATEP--VKEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQ 206
Query: 217 DAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEK 276
++L+ + + +F ++++D ++ ++LS + V F HNDM +LE
Sbjct: 207 GSVLYGQDFCAAPSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLEC 266
Query: 277 LIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIG 336
L+ E Q + + + I EG++ G +A LP+L +LK KYK LFVDE SIG
Sbjct: 267 LLNELTEQEKLEKLPAIPRKFIVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVDETFSIG 326
Query: 337 AMGPSGRGVCDFFGIP-CSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGE 395
+G +GRG+ + F + + IDI +G++ + G+ GG++ D + R+ +
Sbjct: 327 VLGATGRGLSEHFNMDRATAIDITVGSMATALGSTGGFVLGDSVMCLHQRIGSNAYCFSA 386
Query: 396 PTPAPVLAQIASSLKTITGDINPGEGQERLQR 427
PA + ++ LK + + + + ++L +
Sbjct: 387 CLPAYTVTSVSKVLKLMDSNNDAVQTLQKLSK 418
>7291697 [H] KOG1360 5-aminolevulinate synthase
Length = 539
Score = 120 bits (302), Expect = 4e-27
Identities = 100/369 (27%), Positives = 177/369 (47%), Gaps = 19/369 (5%)
Query: 161 SYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAIL 220
S +YLG + G A +A +++G +GG R G + H E +A+ KE A+L
Sbjct: 146 SNDYLGMSAHPG-VKRAVQDALNRHGSGAGGTRNISGNSLHHERLESKLAELHQKEAALL 204
Query: 221 FSMGYGTNAN--FFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKLI 278
F+ + N + F + L C + SD+ NH S+ G+R SG F+HND+ L +L+
Sbjct: 205 FTSCFVANDSTLFTLAKLLPGCEIFSDAGNHASMIMGIRNSGVPKHIFRHNDVDHLHQLL 264
Query: 279 REQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAM 338
++ T + KI+ E ++SM G + L +L+++ ++ F+DE H++G
Sbjct: 265 KQ--------TDKSVPKIV-AFETVHSMTGAICPLEELLDVAHEHGAITFIDEVHAVGLY 315
Query: 339 GPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPTP 398
G G GV + G+ +DI+ GTL K+FG GGYIA ++D R + P
Sbjct: 316 GDHGAGVGERDGV-LHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIRSYAAGFIFTTSLP 374
Query: 399 APVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPML 458
VL ++ + + EG++ N YL+ L+R GF V S +IP+
Sbjct: 375 PTVLCGALEAVNILASE----EGRQLRHLHQRNVSYLKSLLKREGFPVEE-TPSHIIPIK 429
Query: 459 LYAPSKMPAFSRMMLQR-KIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINEV 517
+ P K S +++++ + + YP + ++R + T E ++ L+ + +V
Sbjct: 430 IGDPLKSSQISNVLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKV 489
Query: 518 GDKLFLKVS 526
+ + L +
Sbjct: 490 WEMVDLSTN 498
>Hs20559517 [O] KOG1357 Serine palmitoyltransferase
Length = 121
Score = 117 bits (294), Expect = 4e-26
Identities = 58/112 (51%), Positives = 80/112 (70%)
Query: 400 PVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPMLL 459
P+ QI SLK I G +G +R+Q++A N RY R LQ +GFI+YG ++ V+P+LL
Sbjct: 4 PIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLL 63
Query: 460 YAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLL 511
Y P K+ AF+R ML++KI VVVV +PATPL E+R RFCVSAA T+E +D ++
Sbjct: 64 YMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVI 115
>SPAC2F3.09 [H] KOG1360 5-aminolevulinate synthase
Length = 558
Score = 116 bits (291), Expect = 8e-26
Identities = 99/345 (28%), Positives = 154/345 (43%), Gaps = 20/345 (5%)
Query: 180 EATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDS- 238
+ + YG +GG R G V EK +A K A++F Y N ++
Sbjct: 199 QCIETYGGGAGGTRNIAGHNQHAVRLEKSLADLHQKPAALVFGSCYVANDATLSTLGRKL 258
Query: 239 -KCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKII 297
C+ +SD +NH S+ G+R S FKHND+ LE + +RP I
Sbjct: 259 PNCIFLSDEMNHASMINGIRNSRCEKIIFKHNDLVDLEAKL------ASLPLNRPK---I 309
Query: 298 ICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDID 357
I E +YSM G +A + ++ +L KKY F+DE H++G GP G GV + S +D
Sbjct: 310 IAFESVYSMSGNVAPISEICDLAKKYGAITFLDEVHAVGMYGPRGAGVAEETPGLLSRVD 369
Query: 358 IMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDIN 417
I+ GTL KS+G GGYIAA ++D R P + T P + + T +
Sbjct: 370 IITGTLAKSYGCVGGYIAASSTLVDMIR--SLAPGFIFTTSLPPHVMVGA--LTAVEHLK 425
Query: 418 PGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIP-MLLYAPSKMPAFSRMMLQRK 476
+ QR A R ++ +L +G V D+ ++P M+ A A ++
Sbjct: 426 VSNVEREQQRSA--VRRVKQSLSEIGIPVLS-NDTHIVPAMVGDAHLAKLASDSLLHDHN 482
Query: 477 IAVVVVAYPATPLIESRVRFCVSAA-LTKEDIDYLLQHINEVGDK 520
I V + +P + R+R + A T+ + L +N+V K
Sbjct: 483 IYVQSINFPTVSVGTERLRITPTPAHNTEHYVQSLTNAMNDVWSK 527
>At5g04620 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobutyrate-CoA
ligase
Length = 469
Score = 110 bits (275), Expect = 6e-24
Identities = 103/392 (26%), Positives = 167/392 (42%), Gaps = 60/392 (15%)
Query: 151 GTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVA 210
G L S +YLG + S + AA A +YG+ G G T H + E +A
Sbjct: 99 GRFKKLLLFSGNDYLGLS-SHPTISNAAANAVKEYGMGPKGSALICGYTTYHRLLESSLA 157
Query: 211 QFVGKEDAILFSMGYGTN--------------ANFFNSFLDSKCLVISDSLNHTSIRTGV 256
Q KED ++ G+ N A + K + SD+LNH SI GV
Sbjct: 158 QLKKKEDCLVCPTGFAANMAAMVAIGSVASLLAASGKPLKNEKVAIFSDALNHASIIDGV 217
Query: 257 RLS----GAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMAN 312
RL+ V ++H D+ ++ K+ ++ + L+SM+G A
Sbjct: 218 RLAERQGNVEVFVYRHCDI-----------------SNCKMKRKVVVTDSLFSMDGDFAP 260
Query: 313 LPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGG 372
+ +L +L+KKY L +D+AH G +G GV + F +D+D+ +GTL+K+ G GG
Sbjct: 261 MEELSQLRKKYGFLLVIDDAHGTFVCGENGGGVAEEFNCE-ADVDLCVGTLSKAAGCHGG 319
Query: 373 YIA-ADKW---IIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRI 428
+IA + KW I R R + + P A A + + K I E + + +
Sbjct: 320 FIACSKKWKQLIQSRGRSFIFSTAIPVPMAAAAYAAVVVARKEIWRRKAIWERVKEFKEL 379
Query: 429 AFNARYLRLALQRLGFIVYGI-ADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPAT 487
+ G+ SP+I +++ K SR +L+ V+ + P
Sbjct: 380 S------------------GVDISSPIISLVVGNQEKALKASRYLLKSGFHVMAIRPPTV 421
Query: 488 PLIESRVRFCVSAALTKEDIDYLLQHINEVGD 519
P R+R +SAA T ED+ L+ ++ D
Sbjct: 422 PPNSCRLRVTLSAAHTTEDVKKLITALSSCLD 453
>CE06500 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobutyrate-CoA
ligase
Length = 366
Score = 95.5 bits (236), Expect = 2e-19
Identities = 69/227 (30%), Positives = 114/227 (49%), Gaps = 11/227 (4%)
Query: 297 IICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDI 356
+I +G++SM+G +A L + L +KY LF+DE H+ G G +GRG + G
Sbjct: 146 LIVTDGVFSMDGDVAPLGDITSLAEKYNALLFIDECHATGFFGKTGRGTAEAVG---GRP 202
Query: 357 DIMMGTLTKSFGAA-GGYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGD 415
D++ TL K+ G + GGY K +ID R + P+ + AP + + SS+K
Sbjct: 203 DVINSTLGKALGGSMGGYTTGPKPLIDLLR-QRSRPYLFSNSLAPSI--VGSSIKVFDLL 259
Query: 416 INPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADS-PVIPMLLYAPSKMPAFSRMMLQ 474
+N LQ N + R ++ GF + G + P+ P+LL + +L+
Sbjct: 260 MNDSSFIGSLQT---NVSHFRKSMAANGFTILGNDPTHPICPVLLGDAKLAATMADELLK 316
Query: 475 RKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINEVGDKL 521
I V+ ++P P ++R+R +SAA +K+ ID L++ VG KL
Sbjct: 317 MGIYVIGFSFPVVPKGKARIRVQISAAHSKQHIDQLIEAFATVGKKL 363
>Hs18597111 [E] KOG1359 Glycine C-acetyltransferase/2-amino-3-ketobutyrate-CoA
ligase
Length = 348
Score = 92.4 bits (228), Expect = 2e-18
Identities = 85/323 (26%), Positives = 138/323 (42%), Gaps = 60/323 (18%)
Query: 197 GTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGV 256
GT +H E +A+F +EDAIL+ NA F L + V+SD LN SI G+
Sbjct: 78 GTQSIHKNLEAKIARFHQREDAILYPSCCDANAGLFEVLLRPEDAVLSDELNCASIIHGI 137
Query: 257 RLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKL 316
L A + H D+ LE ++E ++ HR ++ +G +SM+G + L K+
Sbjct: 138 CLCKAHKYHYCHLDVAYLETKLQE------AQKHR---LFLVATDGAFSMDGDIVPLQKI 188
Query: 317 VELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSF-GAAGGYIA 375
L +Y +FVDE H+ G +G +G+G + G+ + I+ TL K+ GA+GGY
Sbjct: 189 CRLASRYGALVFVDECHATGFLGLTGQGTDELLGV-MGQVTIINSTLGKALGGASGGYTT 247
Query: 376 ADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYL 435
+ F L P V+ + +L + E +Q +A ++
Sbjct: 248 GPGPLPYLFSNSL---------PPAVVGCTSKALDLLM------ESNTIVQSMAARTQWF 292
Query: 436 RLALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVR 495
++ GF V G A P+ P ++++R
Sbjct: 293 CSKMEAAGFTVSG-ASHPIRPG---------------------------------KAQIR 318
Query: 496 FCVSAALTKEDIDYLLQHINEVG 518
+SA +EDIDY ++ EVG
Sbjct: 319 IQISALHNEEDIDYHVEAFVEVG 341
>ECU02g0860 [O] KOG1358 Serine palmitoyltransferase
Length = 422
Score = 80.1 bits (196), Expect = 8e-15
Identities = 77/351 (21%), Positives = 158/351 (44%), Gaps = 42/351 (11%)
Query: 179 LEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDS 238
++ KYGV + GPR GT DLH+ E+ + + +G E +I++ + + F
Sbjct: 100 IDVIRKYGVGTCGPRGFYGTLDLHLDLEETITKELGAEASIVYPNSFTAINSIITCFCKQ 159
Query: 239 KCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIII 298
+ +V ++ +I G+ LS + KT + + LE + P + +
Sbjct: 160 QDIVFYHEDSNEAILRGIELSRS--KTIEFGSISDLEIKL--------EYFGNPNVRNFV 209
Query: 299 CVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDI 358
VEGL+ G + + +++EL+ KYK + +DE++SI + RGVC GI +IDI
Sbjct: 210 VVEGLFRNTGRIIEIRRILELRNKYKFRIILDESYSIPLL--DKRGVCGMEGIGIKEIDI 267
Query: 359 MMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINP 418
++G+L+ ++G + D +L ++ + P A + +++ I + +
Sbjct: 268 VIGSLSGGLCSSGAFATGTHSTADYQKLSGSSYCFSASIPG---AMVKAAILNIRREFDH 324
Query: 419 GEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPMLLYAPSK-----MPAFSRMML 473
E + ++ F+A + Y I S + P+++ A + MP ++L
Sbjct: 325 EELRAKVS--VFHANFKSK--------TYEIVSSVLSPIIIAAKRREMRRSMP--KEILL 372
Query: 474 QRKIAV--------VVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINE 516
+ + + V+V + P +R C+ A++ ++ + L +N+
Sbjct: 373 KEILGIRNELLGDNVIVGFNHNPY--PSLRICLKASMPEDQVARLAVLLNK 421
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.321 0.138 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,578,316
Number of Sequences: 60738
Number of extensions: 1434150
Number of successful extensions: 3031
Number of sequences better than 1.0e-05: 29
Number of HSP's better than 0.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2959
Number of HSP's gapped (non-prelim): 32
length of query: 562
length of database: 30,389,216
effective HSP length: 112
effective length of query: 450
effective length of database: 23,586,560
effective search space: 10613952000
effective search space used: 10613952000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)