ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0645 good I KOG2208 Lipid transport and metabolism Vigilin
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0645 206063 202449 -1205
(1205 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJL080c [I] KOG2208 Vigilin 1058 0.0
SPCC550.14 [I] KOG2208 Vigilin 258 4e-68
Hs4885409 [I] KOG2208 Vigilin 172 2e-42
CE23530 [I] KOG2208 Vigilin 151 5e-36
7302610 [I] KOG2208 Vigilin 126 2e-28
Hs5803195 [T] KOG2279 Kinase anchor protein AKAP149 contains KH ... 54 1e-06
Hs10092617 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and rel... 53 3e-06
>YJL080c [I] KOG2208 Vigilin
Length = 1222
Score = 1058 bits (2737), Expect = 0.0
Identities = 559/1124 (49%), Positives = 763/1124 (67%), Gaps = 25/1124 (2%)
Query: 104 AKPLRSRNIQEVFSLDLDAQYQITKTEFSSIVQSVKQKYDVSVESTLSKTSRTFLISGSS 163
AK +RS+NIQE F+LDL +Q ITK E S IVQSVK+ +DVSVESTLSK +RTFL+SG +
Sbjct: 101 AKRMRSKNIQEAFTLDLQSQLSITKPELSRIVQSVKKNHDVSVESTLSKNARTFLVSGVA 160
Query: 164 DKIGLAKRELVKKLTKPVNVTFEVPSKTRSAIIGSGGKTIRAISDAAGVKIVVPKEVDEG 223
+ AKRELVKKLTKP+N EVPSK +++IIGSGG+TIR ISDA VKI V KEV+E
Sbjct: 161 ANVHEAKRELVKKLTKPINAVIEVPSKCKASIIGSGGRTIREISDAYEVKINVSKEVNEN 220
Query: 224 TYDSDLEDYSVTISLHGDAESVLVAKSKILDVVKEETKNAKIVLPVEDSKLVPFIDLE-- 281
+YD D++D + +SL GD ESV +AK+KIL +VKEETKNA I L VED K +P+ID+
Sbjct: 221 SYDEDMDDTTSNVSLFGDFESVNLAKAKILAIVKEETKNATIKLVVEDEKYLPYIDVSEF 280
Query: 282 -SVEIPADVKAQLFTNNDPAEIALNGPRDNVKLAKVKVINYLNELGLKIVVKKEKVPFKF 340
S E +VK Q + + +I + GPR+ K K + +YL +L + +K K+P KF
Sbjct: 281 ASDEGDEEVKVQFYKKS--GDIVILGPREKAKATKTSIQDYLKKLASNLDEEKVKIPSKF 338
Query: 341 HPLVKPSELNEKFHVEVQAPSISGDDQFVFIGSSDNVNEAIVYAKNSSKFHTVESLEISK 400
L+ EL EK++V V PS D+ F+G D V EAI YA++SSK + VESL+ISK
Sbjct: 339 QFLIDAEELKEKYNVIVTFPSTPDDELVSFVGLRDKVGEAITYARSSSKSYVVESLDISK 398
Query: 401 AHGKNVKHAKNLILYFQKYNVLDQITEDFPQVQVVLPKVESIPALESVSITLISNNDAAD 460
AH KN+ HAKNLI+YF KY+VL + E P V++ LP ++S+P E+V+I + + +D A+
Sbjct: 399 AHSKNLTHAKNLIMYFTKYSVLKGLEESHPNVKISLPSIQSLPTAETVTIHISAKSDEAN 458
Query: 461 AIKTVRKQIVALVNELSPEQTLTISDLDYHLFHKDIKQILVSTESDVPFIQLGDCFPGND 520
IK VRK++++ VN + P +TL I+DLDY LF IK L+++ES V F+Q GD +P ++
Sbjct: 459 DIKAVRKELISFVNNIPPSETLVITDLDYELFGGSIKHCLLASESSVAFVQFGDYYPNDN 518
Query: 521 DILLITKINEDDFKPSDDELKVKLESVNQQLEPIRKKQSLLASNVVSLAKKEQDELLGES 580
ILL+ ++DFKPS +E++ L N+ L +R KQ+ + + +++ QD L S
Sbjct: 519 SILLVALTEDEDFKPSIEEIQASLNKANESLNSLRTKQNNMETKTYEFSEEVQDSLFKPS 578
Query: 581 KVTLNLINEAVSHAGAHALIKLSTPSVNQITIRGDDHGCKIASAAVKSIVENSSTESKIT 640
T LI E +S H IKL TP NQ+T+RGD+ K A+ +SI+ + S++SK+T
Sbjct: 579 SATWKLIMEDISEQEGHLQIKLHTPEENQLTVRGDEKAAKAANKIFESILNSPSSKSKMT 638
Query: 641 FQVPTNVVSRLIGPKGANLQQIREKFDVQTFIPQD-----SKDENTDVTLTGLQYNLDQA 695
+P N V+RLIG KG+NLQQIREKF Q IP + SKD+ +VTLTGL+YNL A
Sbjct: 639 VNIPANSVARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHA 698
Query: 696 KTYILAEAKKWSDIITKELIVPMKYHRTLSGPQGTYRIRLENKYSVFIRFPKDSELVTIR 755
K Y+ AEAKKW+DIITKELIVP+K+H +L GP GTYR RL+ KY+VFI FP+D+E+VTIR
Sbjct: 699 KKYLAAEAKKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYNVFINFPRDNEIVTIR 758
Query: 756 GPSRGVKAAYDELKALLDFEIENGHKELLKVPVDYVTRVIGKSGETINDIKAEYGVELNF 815
GPSRGV A++ELKALLDFE+ENGHK ++ VP ++V R+IGK+G+ INDI+AEYGVE++F
Sbjct: 759 GPSRGVNKAHEELKALLDFEMENGHKMVINVPAEHVPRIIGKNGDNINDIRAEYGVEMDF 818
Query: 816 LDKTDSEKAKEAGEVELEITGSRSSIKEAANKVKSIIDQASNFETVTLEDIDSKYYSDII 875
L K+ KA+E GEVELEITGSR +IK+AA +V+SI+ +AS+F T L+ ID KY+ I+
Sbjct: 819 LQKSTDPKAQETGEVELEITGSRQNIKDAAKRVESIVAEASDFVTEVLK-IDHKYHKSIV 877
Query: 876 GRSGSQLKEIISKAGGDEIRNKRVNIPDASSEDKVITIFGPSDFXXXXXXXXXXXXSGLE 935
G G L+EIISKAGG+EIRNK V+IP+A SE+K IT+ GP F E
Sbjct: 878 GSGGHILREIISKAGGEEIRNKSVDIPNADSENKDITVQGPQKFVKKVVEEINKIVKDAE 937
Query: 936 NSITEELNIPQEKFGALIGPAGSVRRELETEFKVRIHVPNKNSSDEKVTVSGSPANXXXX 995
NS+T+ ++IP E+ GALIGP G VRR+LE+EF + + VPNK+ K+T++G+P N
Sbjct: 938 NSVTKTIDIPAERKGALIGPGGIVRRQLESEFNINLFVPNKDDPSGKITITGAPENVEKA 997
Query: 996 XXXXXXXXXRDSFDLEIAVPAKYHSYVSNSGLIFQTLRNEFSIDVSHGNLTRTAQSLSRA 1055
R++FD E+ VPA + YVS G Q LR + S++V GN ++ A L+RA
Sbjct: 998 EKKILNEIIRENFDREVDVPASIYEYVSERGAFIQKLRMDLSVNVRFGNTSKKANKLARA 1057
Query: 1056 NYKVP-ENVAG---GEN-ESSNVLIQSV-TETEAKVDTIPWRLTYSPIDLSDVLGE---- 1105
++P E V G GEN E + I+ V T ++ I RLTY PIDLS +L +
Sbjct: 1058 PIEIPLEKVCGSTEGENAEKTKFTIEEVGAPTSSEEGDITMRLTYEPIDLSSILSDGEEK 1117
Query: 1106 ----DYKKDEESKDQVLEKASKLIEDRIAEAKLVNTEGFVWSKDAKKFNSIVGPNGRNIR 1161
D D K++ L+ A KLI++RIA+A G+VW D ++FN IVGP G NI+
Sbjct: 1118 EVTKDTSNDSAKKEEALDTAVKLIKERIAKAPSATYAGYVWGADTRRFNMIVGPGGSNIK 1177
Query: 1162 EIRNATKTVIHVPRKSDKVNNVIYVLGSEEGVKKAAELICKRLK 1205
+IR A +I+VPRKSDKVN+V+Y+ G++ GV+KA E++ K L+
Sbjct: 1178 KIREAADVIINVPRKSDKVNDVVYIRGTKAGVEKAGEMVLKSLR 1221
>SPCC550.14 [I] KOG2208 Vigilin
Length = 1279
Score = 258 bits (659), Expect = 4e-68
Identities = 262/1165 (22%), Positives = 510/1165 (43%), Gaps = 156/1165 (13%)
Query: 132 SSIVQSVKQKYDVSVE-STLSKTSRT-FLISGSSDKIGLAKRELVKKLTKPVNVTFEVPS 189
+ IV++V + + ST SKT T FLI G + + A+R+++K + + T P
Sbjct: 174 AEIVRTVMHQTSTRINVSTASKTKNTTFLIQGKTSAVKAARRQILKLIGRRETKTMPCPV 233
Query: 190 KTRSAIIGSGGKTIRAISDAAGVKIVVPK---------------EVDEGTYDSDLEDYS- 233
AIIG+ G+ +++I D +I +PK E +E + S L+D
Sbjct: 234 FVVGAIIGTNGQNLKSIMDRTSTRIQIPKRNNTANESSDDAKKPEKEENSAASTLDDLEP 293
Query: 234 ----VTISLHGDAESVLVAKSKILDVVKEETKNAKIVLPVEDSKLVPFI------DLESV 283
TI++ GD E V +A+ I ++ E T N + + ++L + +++ +
Sbjct: 294 QYEMTTITIEGDFEGVELAQKDIEAIINERTSNTTVRISHISTELYSLLRGPDGKNIKEL 353
Query: 284 EIPADVKAQL-FTNNDPA----EIALNGPRDNVKLAKVKVINYLNELGLKIVVKKEKVPF 338
E D+K Q+ F DP+ I L+G + V+ + + EL + +P
Sbjct: 354 EEGRDLKVQIPFAYLDPSAPVNPIVLSGEKSAVRECALYLQGQAEELLRTTIPTMLPIPR 413
Query: 339 KFHPLVKP------SELNEKFHVEVQAPSISGDDQFVFI-GSSDNVNEAIVYAKNSSKFH 391
+ H + ++ K V P I+GD V + G + N++E I +
Sbjct: 414 RQHRFINGEKGVGIQDILRKSGCSVILPPINGDSDVVSVRGPALNISEGIRLTLERANST 473
Query: 392 TVESLEISKAH--GKNVKHAKNLI--LYFQKYNVLDQITEDFPQVQVVLPKVESIPALES 447
V+++ I+ A+ KN +++ L+ + ++ E+ VQ LPK E + + +
Sbjct: 474 IVDAVNITTAYASSKNPFDIASIVARLFLRSRKLIP--LEEECAVQYHLPKREELQSNSN 531
Query: 448 VSITLISNNDAADAIKTVRKQIVALVNEL--SPEQTLTISDL--DYHLFHKDIKQILVST 503
++ + + + +A++ R +++ALVN+ S +TI L Y + K +
Sbjct: 532 KTVIIEISGKSQEAVREGRAKLLALVNQFPESKFYKVTIDPLLQRYVIGSKGKNLQKLRN 591
Query: 504 ESDVPFIQLGDCFPGNDDILLITKINEDDFKPSDDELKVKLESVNQQLEPIRKKQSLLAS 563
E V + +G+ + D +++ I DD K S D+++ +L + + ++ + + + S
Sbjct: 592 EHQVELL-VGE-YGEEDPDVIVCYIGADDGK-SPDQIQKELADLAESVKSSAEASAKIVS 648
Query: 564 NVVSLAKKEQDELLGESKVTLNLINEAVSHAGAHALIKLSTPSV------NQITIRGDDH 617
++ + ++G TLN I + + + +++L S + + IRG
Sbjct: 649 EIIQVPSVYHKHIVGPKGTTLNAI---IGKSEENVIVQLGKVSYRPDSTDDDVYIRGFSK 705
Query: 618 GCKIASAAVKSIVENSSTESKI-----TFQVPTNVVSRLIGPKGANLQQIREKFDVQTFI 672
+ + +K +V ++ + F P +IG G+N+ +RE VQ +
Sbjct: 706 DVERVVSEIKQVVRDAKNHEILHSHVEEFDFPAQYSKNVIGKNGSNVSSLREDLGVQINV 765
Query: 673 PQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKELIVPMKYHRTLSGPQGTYR 732
E + + G++ N+++ I ++ + D + +P +HR L G G Y
Sbjct: 766 ------EEGHIRIQGIKKNVEETAARIKSQIEALIDDTILRVNIPNDFHRQLIGSNGKYV 819
Query: 733 IRLENKYSVFIRFPKDSEL----------------VTIRGPSRGVKAAYDELKALLDFEI 776
RLE K+SV +RFP++ + V IRG + V AA EL L ++E
Sbjct: 820 RRLEEKFSVRVRFPREDDSSNSTGNELMKPTSPDEVVIRGGKKSVAAAKQELLELYEYEK 879
Query: 777 ENGHKELLKVPVDYVTRVIGKSGETINDIKAEYGVELNFLDKTDSEKAKEAGEVELEITG 836
+ + +P V+RV+G++G T+ +I+ ++ V+++ D + E + + G
Sbjct: 880 SIAYTSTIDIPSKAVSRVVGRNGSTVENIRTQFDVKIDIGDVSTEE------TTPVSVRG 933
Query: 837 SRSSIKEAANKVKSIIDQASNFETVTLEDIDSKYYSDIIGRSGSQLKEIISKAGG--DEI 894
+++ ++ A ++ +I ++ N ++ ID +Y+ +IG +GS+L+ I + GG D+
Sbjct: 934 AKADVENAIKEISAIAEEVKNLVEKVIK-IDREYHRYLIGPNGSKLQNTIKECGGSTDKT 992
Query: 895 RNKR-VNIPDASSEDK--VITIFGPSDFXXXXXXXXXXXXSGLENSITEELNIPQEKFGA 951
R ++ + +SE++ + + G + L+N + E++ +PQ +
Sbjct: 993 ETARLISFSNGNSEEERNSVVLRGDKEIVEALETRLLEIVEELKNQVEEKIEVPQRCISS 1052
Query: 952 LIGPAGSVRRELETEFKVRIHVPNKNSSDEKVTVS--GSPANXXXXXXXXXXXXXRDSFD 1009
+IG GS RR++E + +++PN +E VT++ GSP N +
Sbjct: 1053 IIGRMGSTRRDIERKTSTMLNIPNVLDPEETVTITIVGSPENCEKAKEMIQEKVA-SQYT 1111
Query: 1010 LEIAVPAKYHSYVSNSGLIFQTLRNEFSIDVSHGNLTRTAQSLSRANYKVPENVAGGENE 1069
I VP + + G++ + LR++ + V PE
Sbjct: 1112 QMITVPDTVYESIM-KGILMKKLRSDLKVFVD-----------------TPE-------- 1145
Query: 1070 SSNVLIQSVTETEAKVD-----TIPWRLT---YSPIDLSDVLGEDYKKDEESKDQVLEKA 1121
I+ V TE ++ PW+L Y+ S+ +K++ E LEK+
Sbjct: 1146 -----IKPVQPTEVVLEDHEDGVFPWKLVTHDYTGSSSSEWAVRGHKENVEKAIASLEKS 1200
Query: 1122 SK-LIEDRIAEAKLVNTEGFVWSKDAKKFNSIVGPNGRNIREIRNATKTVIHVPRKSDKV 1180
K ++E+ IA + I+G G I +IR + I VPR
Sbjct: 1201 IKQVMENCIAYLGI----------PTNLHRRIIGSGGSIINKIRKIAQVKIDVPRTPG-- 1248
Query: 1181 NNVIYVLGSEEGVKKAAELICKRLK 1205
+ ++ V GS GV KA +LI +RL+
Sbjct: 1249 DEIVVVQGSRAGVVKAKDLIFERLQ 1273
>Hs4885409 [I] KOG2208 Vigilin
Length = 1268
Score = 172 bits (437), Expect = 2e-42
Identities = 261/1196 (21%), Positives = 493/1196 (40%), Gaps = 174/1196 (14%)
Query: 105 KPLRSRNIQEVFSLDLDAQY-----QITKTEFSSIVQSVKQKYDVSVESTLSKTSR-TFL 158
+P+++ I +VF + L+ + Q + E + I + Q+ +E +L+K + +
Sbjct: 69 RPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIM 128
Query: 159 ISGSSDKIGLAKRELVKKLTKPVNVTFEVPSKTRSAIIGSGGKTIRAISDAAGVKIVVPK 218
+SG D + A++++V +L + T +P + +IG G+ ++ + KI +P+
Sbjct: 129 VSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPR 188
Query: 219 EVDEGTYDSDLEDYSVTISLHGDAESVLVAKSKILDVVKEETKNAKIVLPVEDSKLVPFI 278
+D S I + G E + A+ ++L + E+ K A L VE + PFI
Sbjct: 189 P----------DDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKA-FHPFI 237
Query: 279 DLESVEIPADVKAQLFTN-NDP------AEIALNGPRDNVKLAKVKVINYLNELGLK--- 328
+ ++ + T N P EI G ++ + A ++ E K
Sbjct: 238 AGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTT 297
Query: 329 --IVVKKEKVPFKFHPLVKP-SELNEKFHVEVQ-APSISGDDQFVFIGSSDNVNEAI--V 382
+ VKK + + P E+ E+ V V+ PS S + + G + + +A+ V
Sbjct: 298 IAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEV 357
Query: 383 YAKNSSKFHTVESLEISKAHGKNVKHAKNLILYFQKYNVLDQITEDFPQVQVVLPKVESI 442
YAK S +S + H + +K L +IT+ P+V + + E
Sbjct: 358 YAK-------ANSFTVSSVAAPSWLHR---FIIGKKGQNLAKITQQMPKVHIEFTEGEDK 407
Query: 443 PALESVSITLISNNDAADAIKTVRKQIVALVNELSPEQTLTISDLDY---HLFHKDIKQI 499
LE + + ++QI +V +L I+ +DY ++ HK + +
Sbjct: 408 ITLEG----------PTEDVNVAQEQIEGMVKDL-------INRMDYVEINIDHKFHRHL 450
Query: 500 LVSTESDVPFIQLGDCFPGNDDILLITKINEDDFKPSDDELKVKLESVNQQLEPIRKKQS 559
+ + +++ I+ D + +I D S+ +++E Q ++ +++
Sbjct: 451 IGKSGANINRIK--------DQYKVSVRIPPD----SEKSNLIRIEGDPQGVQQAKRELL 498
Query: 560 LLASNVVSLAKKEQDELLGESKVTLNLINE------AVSHAGAHALIKLSTPSVNQ--IT 611
LAS + + +L+ E + +I + + +I P+ +
Sbjct: 499 ELASR---MENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQ 555
Query: 612 IRGD----DHGCKIASAAVKSIVENSSTESKITFQVPTNVVSRLIGPKGANLQQIREKFD 667
+RG + K V +VENS + S F+ +IG GAN+++IRE+ +
Sbjct: 556 LRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFK---QFHKNIIGKGGANIKKIREESN 612
Query: 668 VQTFIPQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKELIVPMKYHRTLSGP 727
+ +P ++ + T + +TG + N + A++ IL+ K ++I E+ +P K H +L G
Sbjct: 613 TKIDLPAENSNSET-IIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGT 671
Query: 728 QG-TYRIRLENKYSVFIRFPKD---SELVTIRGPSRGVKAAYDELKALLDFEIENGHKEL 783
+G R +E V I FP + S+ V IRGPS V+ A +L L + +
Sbjct: 672 KGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVD 731
Query: 784 LKVPVDYVTRVIGKSGETINDIKAEYGVELNFLDKTDSEKAKEAGEVELEITGSRSSIKE 843
++ +Y +IGK G I ++ G + F A++ + + I G +++E
Sbjct: 732 IRAKPEYHKFLIGKGGGKIRKVRDSTGARVIF------PAAEDKDQDLITIIGKEDAVRE 785
Query: 844 AANKVKSIIDQASNFETVTLED---IDSKYYSDIIGRSGSQLKEIISKAGGDEIRNKRVN 900
A +++++I N +ED +D K++ + R G L+EI + GG V+
Sbjct: 786 AQKELEALIQNLDN----VVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGG-----VMVS 836
Query: 901 IPDASSEDKVITIFGPSDFXXXXXXXXXXXXSGLENSITEELNIPQEKFGALIGPAGSVR 960
P + ++ +T+ G D LE +T E IPQ+ +++GP GS
Sbjct: 837 FPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRI 896
Query: 961 RELETEFKVRIHVPNK-----NSSDEKVTVSGSPANXXXXXXXXXXXXXRD--------- 1006
+++ +F V+I P++ +S++ V +G A R
Sbjct: 897 QQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGR 956
Query: 1007 ---------------SFDLEIAVPAKYHSYV-SNSGLIFQTLRNEFSIDVSHG------- 1043
+E+ VP H YV G + + +EF +++
Sbjct: 957 KEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSD 1016
Query: 1044 --NLTRTAQSLSRAN----YKVPENVAGGENESSNVLIQSVTETEAKVDTIPWR--LTYS 1095
+T A +L RA +V E A E+ + SVT I R +
Sbjct: 1017 IIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVIT 1076
Query: 1096 PIDLS-DVLGEDYKKDE--ESKDQV----LEKASKLIEDRIAEAKLVNTEGFVWSKDA-- 1146
I L DV + KD+ + +DQ+ EK ++ D I ++V + S+D
Sbjct: 1077 QIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAI--LRIVGELEQMVSEDVPL 1134
Query: 1147 --KKFNSIVGPNGRNIREIRNATKTVIHVPRKSDKVNNVIYVLGSEEGVKKAAELI 1200
+ I+G G+ IR+I + K I P+ N + V G E V++A + I
Sbjct: 1135 DHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHI 1190
>CE23530 [I] KOG2208 Vigilin
Length = 1220
Score = 151 bits (382), Expect = 5e-36
Identities = 237/1128 (21%), Positives = 450/1128 (39%), Gaps = 144/1128 (12%)
Query: 129 TEFSSIVQSVKQKYDVSVESTLSKTSR-TFLISGSSDKIGLAKRELVKKLTKPVNVTFEV 187
+E S Q++ +E + SK T ++ G K A+ +++ L + ++
Sbjct: 83 SEESKKAQAIATATKTRIELSESKDGELTVVVKGERAKAEEARARIIRDLQTQASREIDI 142
Query: 188 PSKTRSAIIGSGGKTIRAISDAAGVKIVVPKEVDEGTYDSDLEDYSVTISLHGDAESVLV 247
P +IG G +R + +I +P + S I++ G E +
Sbjct: 143 PKDHHGRLIGKEGALLRNLEAETNCRIQIPNR----------DGPSSKITITGPREGIQR 192
Query: 248 AKSKILDVVKEETKNAK--IVLPVEDSKLVPFIDLESVEIPADVKAQLFTNNDPAEI--- 302
A + IL V + E K A IV P LV F V P + T N+ +I
Sbjct: 193 AAAHILAVSEREAKLATEHIVCP---KNLVAF-----VRGPKNETYDRLTQNNGVKINIP 244
Query: 303 ---------ALNGPRDNVKLAKVKVINYL----NELGLKIVVKKEKVPFKFHPLVKPS-- 347
++ G +D V ++ + N +++ V + + + +V S
Sbjct: 245 PPHVTNEVISVTGEKDGVLRVAAEIRQIIESKKNVSSIQVAVARTQHRY----IVGQSRS 300
Query: 348 ---ELNEKFHVEVQAPSI-SGDDQFVFIGSSDNVNEAIVYAKNSSKFHTVESLEISKAHG 403
++ +K V+ P+ SG DQ IG++ ++ +A+ + +S+
Sbjct: 301 GIHDVLQKTGCVVEVPAEDSGSDQVTLIGNAQDLAKALALVIERASSVVTQSIS-----A 355
Query: 404 KNVKHAKNLILYFQKYNVLDQITEDFPQVQVVLPKVESIPALESVSITLISNNDAADAIK 463
N H K+LI K L + + VQ+ I LE S + A +
Sbjct: 356 PNWLH-KHLI--GPKGATLTALVPNRNNVQIEFDNSNQI-FLEG------SPEEVKLAFE 405
Query: 464 TVRKQIVALVNELSPEQTLTISDLDYHLFHKDIKQILVSTESDVPFIQLGDCFPGNDDIL 523
+ K++ L EL+ E+ L H+ + L+S D +Q
Sbjct: 406 PLSKEVARLQMELAIEKVKVHPTLHRHVIGRGGS--LISKIKDQHGVQ------------ 451
Query: 524 LITKINEDDFKPSDDELKV--KLESVNQQLEPIRKKQSLLA---SNVVSLAKKEQDELLG 578
IT NE+ + DE+ V K E V + + IR + + S + + ++ ++G
Sbjct: 452 -ITIPNEET---NSDEIVVEGKKEGVKKAVTEIRAIVTKIENEKSRDIIIPQRLHKLIIG 507
Query: 579 ESKVTLNLINEAVSHAGAHALIKLSTPSVNQITIRGD----DHGCKIASAAVKSIVENSS 634
+ +I + SH + + + + IRGD D K +A K EN+
Sbjct: 508 SKGSGVQVIRD--SHPNVSVVFPDAKSKSDVVNIRGDKTEVDAVYKKLTALSKEYAENNY 565
Query: 635 TESKITFQVPTNVVSRLIGPKGANLQQIREKFDVQTFIPQDSKDENTDVTLTGLQYNLDQ 694
++ F+ + ++G GA+++++R++ + + +P+ D+ +T+TG Q N+++
Sbjct: 566 QQTVAIFK---EFLKHIVGKGGASIRKLRDETETRIDLPESGSDDGK-ITVTGKQANVEK 621
Query: 695 AKTYILAEAKKWSDIITKELIVPMKYHRTLSGPQGTYRIRLENKYS-VFIRFPKD---SE 750
A + ++ +++ + + +P K G +E++ V IRFP + S
Sbjct: 622 AVAQLNKIQEELANVAEESIEIPQKVQSRFFGNGRRLISDIEDECGGVHIRFPSEKSEST 681
Query: 751 LVTIRGPSRGVKAAYDELKALLDFEIENGHKELLKVPVDYVTRVIGKSGETINDIKAEYG 810
VTIRGP+ V A L AL + EN ++ +K ++ +IGK G I ++
Sbjct: 682 KVTIRGPAGDVAKAVGLLSALAKDKEENYVEDTVKAKPEFHRFLIGKGGSKIAKLRDTLN 741
Query: 811 VELNFLDKTDSEKAKEAGEVELEITGSRSSIKEAANKVKSIIDQASNFETVTLE-DIDSK 869
V + F + D+EK + + G + + +A ++ I Q S ETV ++ +D K
Sbjct: 742 VRVMFPKEGDAEKET------IHLLGKKEDVPKAKAALEDAIKQLS--ETVDIKITVDPK 793
Query: 870 YYSDIIGRSGSQLKEIISKAGGDEIRNKRVNIPDASSEDKVITIFGPSDFXXXXXXXXXX 929
YY + + R + +KEI + GG I + P ++ ++I G
Sbjct: 794 YYKNFLARGAALVKEIQEQNGGVVI-----SFPKNGTDSSEVSIRGSKQCVEAAKNRIED 848
Query: 930 XXSGLENSITEELNIPQEKFGALIGPAGSVRRELETEFKVRIHVPNK----NSSDEKVTV 985
E IT+ + IP + L+ G+ EL++++ V I PN + ++VTV
Sbjct: 849 VVEDYEKQITDNVTIPAQFHRGLLAGRGAKIHELQSKYNVSIRFPNNREEGSEGSDQVTV 908
Query: 986 SGSPANXXXXXXXXXXXXXRDSFDLEIAVPAKYH-SYVSNSGLIFQTLRNEFSIDVS--- 1041
SG I +P H S + G + L ++ +++S
Sbjct: 909 SGRDTKVEEAKEALLAMV---PISKVIQLPVDMHRSIIGRGGETVRKLMQDYDVNISIPK 965
Query: 1042 ---------HGNLTRTAQSLSRANYKVPENVAGGENESSNVLIQSVTETEAKVDTIPWRL 1092
G Q+L K+ E A E+ S+ I +
Sbjct: 966 DNSSEDITVTGQTENVDQALEALRGKLGEYEAQAEDRKLKQWSMSINVPTDYHQKIIGQR 1025
Query: 1093 TYSPIDLSDVLGEDYKKDEESKDQVL------EKASKL---IEDRIAEAKLVNTEGFVWS 1143
+ L + G E ++ + EKA++ IE+ I+E + + T+ S
Sbjct: 1026 GATITALKEKYGVIINVPREDGNETITIQGYEEKANECAAAIEEMISELRSMFTQEI--S 1083
Query: 1144 KDAKKFNSIVGPNGRNIREIRNATKTVIHVPRKSDKVNNVIYVLGSEE 1191
DA+ ++G G+N++++ + I +PR+ + N++ V G +E
Sbjct: 1084 LDARYHPRLIGQRGKNLKKVMEDYRVEIRLPRQGAEDPNLVVVAGKDE 1131
Score = 113 bits (282), Expect = 2e-24
Identities = 182/929 (19%), Positives = 366/929 (38%), Gaps = 135/929 (14%)
Query: 153 TSRTFLISGSSD---KIGLAKRELVKKLTKPVNVTFEVPSKTRSAIIGSGGKTIRAISDA 209
T+ ++G D ++ R++++ ++ V I+G I +
Sbjct: 249 TNEVISVTGEKDGVLRVAAEIRQIIESKKNVSSIQVAVARTQHRYIVGQSRSGIHDVLQK 308
Query: 210 AGVKIVVPKE---VDEGTYDSDLEDYSVTISLHGDAESVLVAKSKILDVVKEETKNAKIV 266
G + VP E D+ T + +D + ++L + S +V +S + K +
Sbjct: 309 TGCVVEVPAEDSGSDQVTLIGNAQDLAKALALVIERASSVVTQS-----ISAPNWLHKHL 363
Query: 267 LPVEDSKLVPFI-DLESVEIPADVKAQLFTNNDPAEIALNGPRDNVKLAKVKVINYLNEL 325
+ + + L + + +V+I D Q+F P E VKLA + + L
Sbjct: 364 IGPKGATLTALVPNRNNVQIEFDNSNQIFLEGSPEE---------VKLAFEPLSKEVARL 414
Query: 326 GLKIVVKKEKVPFKFHPLVKP------SELNEKFHVEVQAPSI-SGDDQFVFIGSSDNVN 378
+++ ++K KV H V S++ ++ V++ P+ + D+ V G + V
Sbjct: 415 QMELAIEKVKVHPTLHRHVIGRGGSLISKIKDQHGVQITIPNEETNSDEIVVEGKKEGVK 474
Query: 379 EAIVYAKNSSKFHTVESLEISKAHGKNVKHAKNLILYFQKYNVLDQITEDFPQVQVVLPK 438
+A+ + V +E K+ + + ++ K + + I + P V VV P
Sbjct: 475 KAVTEIRA-----IVTKIENEKSRDIIIPQRLHKLIIGSKGSGVQVIRDSHPNVSVVFPD 529
Query: 439 VESIPALESVSITLISNNDAADAIKTVRKQIVALVNELSP---EQTLTI-SDLDYHLFHK 494
+S +S + + + DA V K++ AL E + +QT+ I + H+ K
Sbjct: 530 AKS----KSDVVNIRGDKTEVDA---VYKKLTALSKEYAENNYQQTVAIFKEFLKHIVGK 582
Query: 495 ---DIKQILVSTESDVPFIQLGDCFPGNDDILLITKINEDDFKPSDDELKVKLESVN--- 548
I+++ TE+ + + G +D + +T + K K++ E N
Sbjct: 583 GGASIRKLRDETETRIDLPESGS----DDGKITVTGKQANVEKAVAQLNKIQEELANVAE 638
Query: 549 QQLEPIRKKQSLLASNVVSLAKKEQDELLG-----------ESKVTL------------- 584
+ +E +K QS N L +DE G +KVT+
Sbjct: 639 ESIEIPQKVQSRFFGNGRRLISDIEDECGGVHIRFPSEKSESTKVTIRGPAGDVAKAVGL 698
Query: 585 ----------NLINEAVSHA----------GAHALIKL-------------STPSVNQIT 611
N + + V G + KL I
Sbjct: 699 LSALAKDKEENYVEDTVKAKPEFHRFLIGKGGSKIAKLRDTLNVRVMFPKEGDAEKETIH 758
Query: 612 IRGDDHGCKIASAAVKSIVENSSTESKITFQVPTNVVSRLIGPKGANLQQIREKFD-VQT 670
+ G A AA++ ++ S I V + A +++I+E+ V
Sbjct: 759 LLGKKEDVPKAKAALEDAIKQLSETVDIKITVDPKYYKNFLARGAALVKEIQEQNGGVVI 818
Query: 671 FIPQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKELIVPMKYHRTLSGPQGT 730
P++ D +++V++ G + ++ AK I + + IT + +P ++HR L +G
Sbjct: 819 SFPKNGTD-SSEVSIRGSKQCVEAAKNRIEDVVEDYEKQITDNVTIPAQFHRGLLAGRGA 877
Query: 731 YRIRLENKYSVFIRFPKD-------SELVTIRGPSRGVKAAYDELKALLDFEIENGHKEL 783
L++KY+V IRFP + S+ VT+ G V+ A + L A++ ++
Sbjct: 878 KIHELQSKYNVSIRFPNNREEGSEGSDQVTVSGRDTKVEEAKEALLAMVPI------SKV 931
Query: 784 LKVPVDYVTRVIGKSGETINDIKAEYGVELNFLDKTDSEKAKEAGEVELEITGSRSSIKE 843
+++PVD +IG+ GET+ + +Y V ++ SE G+ E + + +++
Sbjct: 932 IQLPVDMHRSIIGRGGETVRKLMQDYDVNISIPKDNSSEDITVTGQTE-NVDQALEALRG 990
Query: 844 AANKVKSIIDQASNFETVTLEDIDSKYYSDIIGRSGSQLKEIISKAGGDEIRNKRVNIPD 903
+ ++ + + ++ + Y+ IIG+ G+ + + K G +N+P
Sbjct: 991 KLGEYEAQAEDRKLKQWSMSINVPTDYHQKIIGQRGATITALKEKYG------VIINVP- 1043
Query: 904 ASSEDKVITIFGPSDFXXXXXXXXXXXXSGLENSITEELNIPQEKFGALIGPAGSVRREL 963
++ ITI G + S L + T+E+++ LIG G +++
Sbjct: 1044 REDGNETITIQGYEEKANECAAAIEEMISELRSMFTQEISLDARYHPRLIGQRGKNLKKV 1103
Query: 964 ETEFKVRIHVPNKNSSDEK-VTVSGSPAN 991
+++V I +P + + D V V+G N
Sbjct: 1104 MEDYRVEIRLPRQGAEDPNLVVVAGKDEN 1132
Score = 107 bits (268), Expect = 9e-23
Identities = 198/1074 (18%), Positives = 422/1074 (38%), Gaps = 121/1074 (11%)
Query: 181 VNVTFEVPSKTRSAIIGSGGKTIRAISDAAGVKIVVPKEVDEGTYDSDLEDYSVTISLHG 240
VN+TF + S RS + S G T A + ++ S+ +D +T+ + G
Sbjct: 61 VNITFRLASDERSNKVKSFGSTSEESKKAQAIATATKTRIEL----SESKDGELTVVVKG 116
Query: 241 DAESVLVAKSKILDVVKEETKNAKIVLPVEDSKLVPFID--LESVEIPADVKAQLFTNND 298
+ A+++I+ ++ + + +L+ L ++E + + Q+ +
Sbjct: 117 ERAKAEEARARIIRDLQTQASREIDIPKDHHGRLIGKEGALLRNLEAETNCRIQIPNRDG 176
Query: 299 PA-EIALNGPRDNVKLAKVKVINYLNELGLKIVVKKEKVPFKFHPLVKPSELNEKFHVEV 357
P+ +I + GPR+ ++ A ++ ++E K+ + P V+ + NE +
Sbjct: 177 PSSKITITGPREGIQRAAAHILA-VSEREAKLATEHIVCPKNLVAFVRGPK-NETYDRLT 234
Query: 358 QAPSISGDDQFVFIGSSDNVNEAI-VYAKNSSKFHTVESLEISKAHGKNVKHAKNLILYF 416
Q + + I NE I V + + KNV + +
Sbjct: 235 QNNGVK-----INIPPPHVTNEVISVTGEKDGVLRVAAEIRQIIESKKNVSSIQVAVART 289
Query: 417 QKYNVLDQITEDFPQVQVVLPKVESIPALESVS--ITLISNNDAADAIKTVRKQIVALVN 474
Q ++ Q V V +PA +S S +TLI N + + K + ++
Sbjct: 290 QHRYIVGQSRSGIHDVLQKTGCVVEVPAEDSGSDQVTLIGN------AQDLAKALALVIE 343
Query: 475 ELSPEQTLTISDLDYHLFHKDIKQILVSTESDVPFIQLGDCFPGNDDILL-ITKINEDDF 533
S T +IS ++ HK + +T L P +++ + N+
Sbjct: 344 RASSVVTQSISAPNW--LHKHLIGPKGAT--------LTALVPNRNNVQIEFDNSNQIFL 393
Query: 534 KPSDDELKVKLESVNQQLEPIRKKQSLLASNVVSLAKKEQDELLGESKVTLNLINEAVSH 593
+ S +E+K+ E ++++ + + Q LA V + ++G +LI++
Sbjct: 394 EGSPEEVKLAFEPLSKE---VARLQMELAIEKVKVHPTLHRHVIGRGG---SLISKIKDQ 447
Query: 594 AGAHALIKLSTPSVNQITIRGDDHGCKIASAAVKSIVENSSTESKITFQVPTNVVSRLIG 653
G I + ++I + G G K A +++IV E +P + +IG
Sbjct: 448 HGVQITIPNEETNSDEIVVEGKKEGVKKAVTEIRAIVTKIENEKSRDIIIPQRLHKLIIG 507
Query: 654 PKGANLQQIREKFDVQTFIPQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKE 713
KG+ +Q IR+ + + D+K ++ V + G + +D + A +K++++ ++
Sbjct: 508 SKGSGVQVIRDSHPNVSVVFPDAKSKSDVVNIRGDKTEVDAVYKKLTALSKEYAENNYQQ 567
Query: 714 LIVPMK-YHRTLSGPQGTYRIRLENKYSVFIRFPK---DSELVTIRGPSRGVKAAYDELK 769
+ K + + + G G +L ++ I P+ D +T+ G V+ A +L
Sbjct: 568 TVAIFKEFLKHIVGKGGASIRKLRDETETRIDLPESGSDDGKITVTGKQANVEKAVAQLN 627
Query: 770 ALLDFEIENGHKELLKVPVDYVTRVIGKSGETINDIKAEY-GVELNFLDKTDSEKAKEAG 828
+ + E+ N +E +++P +R G I+DI+ E GV + F SEK++
Sbjct: 628 KIQE-ELANVAEESIEIPQKVQSRFFGNGRRLISDIEDECGGVHIRF----PSEKSE--- 679
Query: 829 EVELEITGSRSSIKEAANKVKSII-DQASNFETVTLEDIDSKYYSDIIGRSGSQLKEIIS 887
++ I G + +A + ++ D+ N+ T++ +++ +IG+ GS++ ++
Sbjct: 680 STKVTIRGPAGDVAKAVGLLSALAKDKEENYVEDTVK-AKPEFHRFLIGKGGSKIAKL-- 736
Query: 888 KAGGDEIRNKRVNIP-DASSEDKVITIFGPSDFXXXXXXXXXXXXSGLENSITEELNIPQ 946
+ N RV P + +E + I + G + L ++ ++ +
Sbjct: 737 ----RDTLNVRVMFPKEGDAEKETIHLLGKKEDVPKAKAALEDAIKQLSETVDIKITVDP 792
Query: 947 EKFGALIGPAGSVRREL-ETEFKVRIHVPNKNSSDEKVTVSGSP--ANXXXXXXXXXXXX 1003
+ + + ++ +E+ E V I P + +V++ GS
Sbjct: 793 KYYKNFLARGAALVKEIQEQNGGVVISFPKNGTDSSEVSIRGSKQCVEAAKNRIEDVVED 852
Query: 1004 XRDSFDLEIAVPAKYH-SYVSNSGLIFQTLRNEFSIDVSHGNLTRTAQSLSRANYKVPEN 1062
+ +PA++H ++ G L++++++ + + P N
Sbjct: 853 YEKQITDNVTIPAQFHRGLLAGRGAKIHELQSKYNVSI-----------------RFPNN 895
Query: 1063 VAGGENESSNVLIQ----SVTET-EAKVDTIP-WRLTYSPIDL-SDVLG----------E 1105
G S V + V E EA + +P ++ P+D+ ++G +
Sbjct: 896 REEGSEGSDQVTVSGRDTKVEEAKEALLAMVPISKVIQLPVDMHRSIIGRGGETVRKLMQ 955
Query: 1106 DY------KKDEESKDQVLEKASKLIEDRI--AEAKLVNTEGFVWSKDAKKFN------- 1150
DY KD S+D + ++ ++ + KL E + K+++
Sbjct: 956 DYDVNISIPKDNSSEDITVTGQTENVDQALEALRGKLGEYEAQAEDRKLKQWSMSINVPT 1015
Query: 1151 ----SIVGPNGRNIREIRNATKTVIHVPRKSDKVNNVIYVLGSEEGVKKAAELI 1200
I+G G I ++ +I+VPR+ N I + G EE + A I
Sbjct: 1016 DYHQKIIGQRGATITALKEKYGVIINVPREDG--NETITIQGYEEKANECAAAI 1067
>7302610 [I] KOG2208 Vigilin
Length = 1268
Score = 126 bits (316), Expect = 2e-28
Identities = 142/662 (21%), Positives = 291/662 (43%), Gaps = 87/662 (13%)
Query: 608 NQITIRGDDHGCKIASAAVKSIVENSSTESKITFQVPT---NVVSRLIGPKGANLQQIRE 664
++I + GD A A + I++N E TF+V T + +IG GAN+ ++++
Sbjct: 389 DKIKLEGDPENVDRAVAYLSEIIKNY--EENFTFEVMTVNPSYYKHIIGKAGANVNRLKD 446
Query: 665 KFDVQTFIPQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKELIVPMKYHRTL 724
+ V I + ++ ++ + G + + QA+ + + K + +K++I+ + HR++
Sbjct: 447 ELKVNINI--EEREGQNNIRIEGPKEGVRQAQLELQEKIDKLENEKSKDVIIDRRLHRSI 504
Query: 725 SGPQGTYRIRLENKY-SVFIRFP---KDSELVTIRGPSRGVKAAYDELKALLDFEIENGH 780
G +G ++++Y V I P +++++V +RGP V + +L L+ E+ H
Sbjct: 505 IGAKGEKIREVKDRYRQVTITIPTPQENTDIVKLRGPKEDVDKCHKDLLKLVKEIQESSH 564
Query: 781 KELLKVPV--DYVTRVIGKSGETINDIKAEYGVELNFLDKTDSEKAKEAGEVELEITGSR 838
+++VP+ + VIGK G I I+ E +++ + D+ + + ITG +
Sbjct: 565 --IIEVPIFKQFHKFVIGKGGANIKKIRDETQTKIDLPAEGDTNEV-------IVITGKK 615
Query: 839 SSIKEAANKVKSIIDQASNFETVTLEDIDSKYYSDIIGRSGSQLKEIISKAGGDEIRNKR 898
++ EA +++ I ++ S+ T ++ I KYY+ IIG G + I+ + GG I+
Sbjct: 616 ENVLEAKERIQKIQNELSDIVTEEVQ-IPPKYYNSIIGTGGKLISSIMEECGGVSIK--- 671
Query: 899 VNIPDASSEDKVITIFGPSDFXXXXXXXXXXXXSGLE-NSITEELNIPQEKFGALIGPAG 957
P++ S+ +TI GP D + + S T E+ Q+ LIG G
Sbjct: 672 --FPNSDSKSDKVTIRGPKDDVEKAKVQLLELANERQLASFTAEVRAKQQHHKFLIGKNG 729
Query: 958 SVRRELETEFKVRIHVPNKNSSDEKV-TVSGSPANXXXXXXXXXXXXXR--DSFDLEIAV 1014
+ R++ RI P+ +D++V T+ G + + + E++V
Sbjct: 730 ASIRKIRDATGARIIFPSNEDTDKEVITIIGKEESVKKAREQLEAIIKECDEVTEGEVSV 789
Query: 1015 PAKYHS-YVSNSGLIFQTLRNE----------FSIDVSHGNLTRTAQSLSRANYKVPENV 1063
K+H +V+ G I + E I+ + + A ++ E V
Sbjct: 790 DPKHHKHFVAKRGFILHRISEECGGVMISFPRVGINSDKVTIKGAKDCIEAARQRIEEIV 849
Query: 1064 AGGENESS-----------------NVLIQSVT-ETEAKVDTIPWRLTYSPID--LSDVL 1103
A E +++ +Q VT E + ++ P R P++ +
Sbjct: 850 ADLEAQTTIEVVIPQRHHRTIMGARGFKVQQVTFEFDVQIK-FPDRDATEPVEGLTNGGS 908
Query: 1104 GEDYKKDE-ESKDQVLEKASKLIEDRIAEAKLVNTEGFVWSKDAKK-------------- 1148
GE+ ++E + +Q +EK ++ ++ + + ++ G + +A K
Sbjct: 909 GENGGENEGQEGEQEVEKEAE--QEPVRQCDVIRITGRIEKCEAAKQALLDLIPIEEELS 966
Query: 1149 -----FNSIVGPNGRNIREIRNATKTVIHVPRKSDKVNNVIYVLGSEEGVKKAAELICKR 1203
+I+GP G N+R+ + + +P S+ ++VI V G+ V +A E + K
Sbjct: 967 VPFDLHRTIIGPRGANVRQFMSKHDVHVELP-PSELKSDVIKVCGTPARVAEAREALVKM 1025
Query: 1204 LK 1205
++
Sbjct: 1026 IE 1027
Score = 122 bits (307), Expect = 3e-27
Identities = 143/664 (21%), Positives = 274/664 (40%), Gaps = 86/664 (12%)
Query: 541 KVKLESVNQQLEPIRKKQSLLASNVVSLAKKEQDELLGESKVTLNLINEAVSHAGAHALI 600
K + Q++ + +Q +S+ +++ K ++G LN + E GA +
Sbjct: 187 KEGIAQAEQEIRQLSAEQYKKSSDRITVPKVYHPFIVGPYSENLNKLQE---ETGARINV 243
Query: 601 KLSTPSVNQITIRGDDHGCKIASAAVKSIVENSSTE-SKITFQVPTNVVSRLIGPKGANL 659
++I I G+ A A V++I ++ + S ++ +V +IGPKG+ +
Sbjct: 244 PPQQVQKDEIVISGEKDAVAAAKAKVEAIYKDMEKKCSTVSVEVAKPKHRYVIGPKGSTI 303
Query: 660 QQIREKFDVQTFIPQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKELIVPMK 719
+I + V +P + T +TL G Q L A T + +K + + + E+
Sbjct: 304 AEILQLTGVSVEMPPNDSPSET-ITLRGPQVALGNALTVVY---QKSNSVKSVEINAAHW 359
Query: 720 YHRTLSGPQGTYRIRLENKY-SVFIRFPKDSELVTIRGPSRGVKAAYDELKALLDFEIEN 778
H+ + G +G +LE +V + +D + + G V A L ++ EN
Sbjct: 360 IHKYVIGRKGANMKQLEEDCPNVNVNCLEDK--IKLEGDPENVDRAVAYLSEIIKNYEEN 417
Query: 779 GHKELLKVPVDYVTRVIGKSGETINDIKAEYGVELNFLDKTDSEKAKEAGEVELEITGSR 838
E++ V Y +IGK+G +N +K E V +N ++ G+ + I G +
Sbjct: 418 FTFEVMTVNPSYYKHIIGKAGANVNRLKDELKVNINIEERE--------GQNNIRIEGPK 469
Query: 839 SSIKEAANKVKSIIDQASNFETVTLEDIDSKYYSDIIGRSGSQLKEIISKAGGDEIRNKR 898
+++A +++ ID+ N ++ + ID + + IIG G +++E+ D R
Sbjct: 470 EGVRQAQLELQEKIDKLENEKSKDVI-IDRRLHRSIIGAKGEKIREV-----KDRYRQVT 523
Query: 899 VNIPDASSEDKVITIFGPSDFXXXXXXXXXXXXSGL-ENSITEELNIPQEKFGALIGPAG 957
+ IP ++ + GP + + E+S E+ I ++ +IG G
Sbjct: 524 ITIPTPQENTDIVKLRGPKEDVDKCHKDLLKLVKEIQESSHIIEVPIFKQFHKFVIGKGG 583
Query: 958 SVRRELETEFKVRIHVPNKNSSDEKVTVSGSPANXXXXXXXXXXXXXR--DSFDLEIAVP 1015
+ +++ E + +I +P + ++E + ++G N D E+ +P
Sbjct: 584 ANIKKIRDETQTKIDLPAEGDTNEVIVITGKKENVLEAKERIQKIQNELSDIVTEEVQIP 643
Query: 1016 AKYH-SYVSNSGLIFQTLRNEFSIDVSHGNLTRTAQSLSRANYKVPENVAGGENESSNVL 1074
KY+ S + G + ++ E + K P + +++S V
Sbjct: 644 PKYYNSIIGTGGKLISSIMEE----------------CGGVSIKFPNS----DSKSDKVT 683
Query: 1075 IQSVTETEAKVDTIPWRLTYSPIDLSDVLGEDYKKDEESKDQVLEKASKLIEDRIAEAKL 1134
I+ + DV E++K Q+LE A+ E +L
Sbjct: 684 IRGPKD--------------------DV--------EKAKVQLLELAN--------ERQL 707
Query: 1135 VNTEGFVWSKDAKKFNSIVGPNGRNIREIRNATKTVIHVPRKSDKVNNVIYVLGSEEGVK 1194
+ V +K + ++G NG +IR+IR+AT I P D VI ++G EE VK
Sbjct: 708 ASFTAEVRAKQ-QHHKFLIGKNGASIRKIRDATGARIIFPSNEDTDKEVITIIGKEESVK 766
Query: 1195 KAAE 1198
KA E
Sbjct: 767 KARE 770
Score = 102 bits (253), Expect = 5e-21
Identities = 173/907 (19%), Positives = 354/907 (38%), Gaps = 138/907 (15%)
Query: 158 LISGSSDKIGLAKRE---LVKKLTKPVN-VTFEVPSKTRSAIIGSGGKTIRAISDAAGVK 213
+ISG D + AK + + K + K + V+ EV +IG G TI I GV
Sbjct: 254 VISGEKDAVAAAKAKVEAIYKDMEKKCSTVSVEVAKPKHRYVIGPKGSTIAEILQLTGVS 313
Query: 214 IVVPKEVDEGTYDSDLEDYSVTISLHGDAESVLVAKSKILDVVKEETKNAKIVLPVEDSK 273
+ +P + S TI+L G VA L VV +++ + K V +
Sbjct: 314 VEMPPN----------DSPSETITLRGPQ----VALGNALTVVYQKSNSVKSV----EIN 355
Query: 274 LVPFIDLESVEIPADVKAQLFTNNDPAEIALNGPRDNVKLAKV-----KVINYLNELGLK 328
+I + QL D + +N D +KL + + YL+E
Sbjct: 356 AAHWIHKYVIGRKGANMKQL--EEDCPNVNVNCLEDKIKLEGDPENVDRAVAYLSE---- 409
Query: 329 IVVKKEKVPFKFHPL-VKPS--------------ELNEKFHVEVQAPSISGDDQFVFIGS 373
++K + F F + V PS L ++ V + G + G
Sbjct: 410 -IIKNYEENFTFEVMTVNPSYYKHIIGKAGANVNRLKDELKVNINIEEREGQNNIRIEGP 468
Query: 374 SDNVNEAIVYAKNSSKFHTVESLEISKAHGKNVKHAKNLILYFQKYNVLDQITEDFPQVQ 433
+ V +A + + ++ LE K+ + + + K + ++ + + QV
Sbjct: 469 KEGVRQAQLELQEK-----IDKLENEKSKDVIIDRRLHRSIIGAKGEKIREVKDRYRQVT 523
Query: 434 VVLPKVESIPALESVSITLISNNDAADAIKTVRKQIVALVNELSPEQTLTISDLDYHLFH 493
+ +P + + ++ + + K ++ LV E+ E + I + FH
Sbjct: 524 ITIPTPQE-------NTDIVKLRGPKEDVDKCHKDLLKLVKEIQ-ESSHIIEVPIFKQFH 575
Query: 494 K--------DIKQILVSTESDVPFIQLGDCFPGNDDILLITKINEDDFKPSDDELKVKLE 545
K +IK+I T++ + GD +++++IT E+ E K +++
Sbjct: 576 KFVIGKGGANIKKIRDETQTKIDLPAEGD----TNEVIVITGKKENVL-----EAKERIQ 626
Query: 546 SVNQQLEPIRKKQSLLASNVVSLAKKEQDELLGESKVTLNLINEAVSHAGAHALIKLSTP 605
+ +L I ++ V + K + ++G ++ I E G S
Sbjct: 627 KIQNELSDIVTEE-------VQIPPKYYNSIIGTGGKLISSIMEECG--GVSIKFPNSDS 677
Query: 606 SVNQITIRGDDHGCKIASAAVKSIVENSSTESKITFQVPTNVVSR--LIGPKGANLQQIR 663
+++TIRG + A + + N + T +V LIG GA++++IR
Sbjct: 678 KSDKVTIRGPKDDVEKAKVQLLELA-NERQLASFTAEVRAKQQHHKFLIGKNGASIRKIR 736
Query: 664 EKFDVQTFIPQDSKDENTDVTLTGLQYNLDQAKTYILAEAKKWSDIITKELIVPMKYHRT 723
+ + P + + +T+ G + ++ +A+ + A K+ ++ E+ V K+H+
Sbjct: 737 DATGARIIFPSNEDTDKEVITIIGKEESVKKAREQLEAIIKECDEVTEGEVSVDPKHHKH 796
Query: 724 LSGPQGTYRIRL-ENKYSVFIRFPK---DSELVTIRGPSRGVKAAYDELKALL-DFEIEN 778
+G R+ E V I FP+ +S+ VTI+G ++AA ++ ++ D E +
Sbjct: 797 FVAKRGFILHRISEECGGVMISFPRVGINSDKVTIKGAKDCIEAARQRIEEIVADLEAQT 856
Query: 779 GHKELLKVPVDYVTRVIGKSGETINDIKAEYGVELNFLDKTDSEKAK------------- 825
+ + +P + ++G G + + E+ V++ F D+ +E +
Sbjct: 857 TIE--VVIPQRHHRTIMGARGFKVQQVTFEFDVQIKFPDRDATEPVEGLTNGGSGENGGE 914
Query: 826 ---EAGEVELEITGSRSSIKEA-ANKVKSIIDQASNFETVTLE--------DIDSKYYSD 873
+ GE E+E + +++ ++ I++ + L+ + +
Sbjct: 915 NEGQEGEQEVEKEAEQEPVRQCDVIRITGRIEKCEAAKQALLDLIPIEEELSVPFDLHRT 974
Query: 874 IIGRSGSQLKEIISKAGGDEIRNKRVNIPDASSEDKVITIFGPSDFXXXXXXXXXXXXSG 933
IIG G+ +++ +SK + V +P + + VI + G
Sbjct: 975 IIGPRGANVRQFMSK------HDVHVELPPSELKSDVIKVCGTPARVAEAREALVKMIED 1028
Query: 934 LE--------NSITEELNIPQEKFGALIGPAGSVRRELETEFKVRIHVPNKNS-SDEKVT 984
E S ++++ E LIG G+V +L + V I +P ++ +D ++
Sbjct: 1029 YEADRADRELRSFVLQVDVDTEFHSKLIGRHGAVINKLRADHDVIISLPKRDEPNDRIIS 1088
Query: 985 VSGSPAN 991
++G AN
Sbjct: 1089 ITGYQAN 1095
>Hs5803195 [T] KOG2279 Kinase anchor protein AKAP149 contains KH and Tudor
RNA-binding domains
Length = 606
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/112 (37%), Positives = 58/112 (51%), Gaps = 8/112 (7%)
Query: 155 RTFLISGSSDKIGLAKRELVKKLTK--PVNVTFEVPSKTRSAIIGSGGKTIRAISDAAGV 212
R LISG ++ AK + + LT+ PV+ VP ++ IIG GG+TIR+I A+G
Sbjct: 97 RVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGA 156
Query: 213 KIVVPKEVDEGTYDSDLEDYSVTISLHGDAESVLVAKSKILDVVKEETKNAK 264
KI KE EGT S I + G + V AK IL+ V E+ + K
Sbjct: 157 KITCDKE-SEGTL-----LLSRLIKISGTQKEVAAAKHLILEKVSEDEELRK 202
>Hs10092617 [AR] KOG2190 PolyC-binding proteins alphaCP-1 and related KH domain
proteins
Length = 339
Score = 53.1 bits (126), Expect = 3e-06
Identities = 36/136 (26%), Positives = 64/136 (46%), Gaps = 21/136 (15%)
Query: 869 KYYSDIIGRSGSQLKEIISKAGGDEIRNKRVNIPDASSEDKVITIFGPSD-----FXXXX 923
K IIG+ G +K++ ++G R+NI + + ++++TI GP+D F
Sbjct: 23 KEVGSIIGKKGETVKKMREESGA------RINISEGNCPERIVTITGPTDAIFKAFAMIA 76
Query: 924 XXXXXXXXSGLENS-------ITEELNIPQEKFGALIGPAGSVRRELETEFKVRIHVPNK 976
+ + NS +T L +P + G+LIG GS +E+ ++ V
Sbjct: 77 YKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGD 136
Query: 977 ---NSSDEKVTVSGSP 989
NS++ VT+SG+P
Sbjct: 137 MLPNSTERAVTISGTP 152
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.311 0.131 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,436,639
Number of Sequences: 60738
Number of extensions: 2697610
Number of successful extensions: 8466
Number of sequences better than 1.0e-05: 7
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 8189
Number of HSP's gapped (non-prelim): 63
length of query: 1205
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1087
effective length of database: 23,222,132
effective search space: 25242457484
effective search space used: 25242457484
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)