ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0699 good T KOG4305 Signal transduction mechanisms RhoGEF GTPase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0699 224253 220270 -1328
(1328 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR425w [T] KOG4305 RhoGEF GTPase 951 0.0
SPCC645.06c [T] KOG4305 RhoGEF GTPase 145 5e-34
SPAC1006.06 [T] KOG4305 RhoGEF GTPase 69 4e-11
YLR371w [T] KOG4305 RhoGEF GTPase 69 5e-11
SPCC645.07 [T] KOG4305 RhoGEF GTPase 57 3e-07
YGR070w [T] KOG4305 RhoGEF GTPase 56 3e-07
>YLR425w [T] KOG4305 RhoGEF GTPase
Length = 1307
Score = 951 bits (2458), Expect = 0.0
Identities = 501/1094 (45%), Positives = 693/1094 (62%), Gaps = 33/1094 (3%)
Query: 248 YYPQPPKMKDVSNGAIGPNEPRLXXXXXXXXXXXXXAFNKNVEEYARHESFGSITGSKPL 307
++ +PP S G + R+ FN + AR SF S+ G+KPL
Sbjct: 223 FFTKPPPPLSTSRNVSGNS--RVSEALESVYSDSDYTFNNS---NARQSSFNSLLGAKPL 277
Query: 308 NNVASITVPTYPFTIDLLDERKLYQCYNISQLSHIYQWLLKVYFEWFNEYVFGKLEFFQI 367
SIT PT PF+I +DE KLYQC N+ +LS IY+W+LKVYFEWFNE VF K++ FQI
Sbjct: 278 ELAPSITAPTQPFSIQSIDEHKLYQCDNVYKLSAIYEWILKVYFEWFNECVFTKIDLFQI 337
Query: 368 VQLLLEFQLPNSCEQDIIDSNVDKIIESLILQGAVRFEDDPETGNQITIIIAGLDTQGVF 427
VQLLLEFQ+P + +QD IDSNVD I+ S I Q AVRF D ++ +++ GLD GVF
Sbjct: 338 VQLLLEFQMPTNFDQDTIDSNVDNIMASFISQKAVRF--DIINDEEVAVVVGGLDITGVF 395
Query: 428 TDLLPCYSYSHIYDDPTTDLKCYSYTCWSSKGSENYRSQLKISEFINKSVGLWTDYWKLT 487
T+LLPCYS+ T L CYS C + S +R ++K+SE INKSVGLWT+YW LT
Sbjct: 396 TELLPCYSFIDNTYGSTNSLICYSNVCTHGQSS-GFRKEIKLSEIINKSVGLWTEYWHLT 454
Query: 488 PEELSEINPKEVKRQSFIFDLIVLEERSLNLANAAVEIYGASFDPALLPDDPNFKSMAYD 547
P++L+EINP+EV+RQSFIFDLI+LEERSLN+A AAVEIYG FD +LLPD+P FK++A+D
Sbjct: 455 PDDLAEINPREVQRQSFIFDLIILEERSLNMATAAVEIYGKRFDKSLLPDEPEFKALAFD 514
Query: 548 IFIPLIELHKDILLSPILWKLKIKGKFIDGVGKIYLKWANDAKQVYVKYAQNMATVHEII 607
IF PLI+LH + LL+PI WKLK +GKFIDGVGKIY KW +AK +Y+ YA+ MATVHEII
Sbjct: 515 IFEPLIQLHTEFLLTPIFWKLKTRGKFIDGVGKIYSKWCGEAKNIYLNYAKAMATVHEII 574
Query: 608 NWEKENNTRFASWLRQIDESTPITRSKLYHDVIFFGGFFKSLQNMPVTLRSVLKCTDPSM 667
WEK+N T+F +WL++ID S ITRSK+YHDVIFFGGFFKSLQNMPVTLRS+LK TDPSM
Sbjct: 575 MWEKKNKTKFVTWLKEIDNSVEITRSKMYHDVIFFGGFFKSLQNMPVTLRSILKNTDPSM 634
Query: 668 DDHEYLRMAIQEIEQLSRLVDKAHGDAIDKRKIVRLARQLIFTSKTGNTVNYLNIQSGND 727
+D+EYL++ I+E+E+L+ V++ HG AID RK+VR ++QL+ ++ + N +Y+N+ G+
Sbjct: 635 EDYEYLKIVIKEVEKLNFEVNQVHGLAIDHRKLVRFSKQLVLSTNSSNATSYVNV-GGST 693
Query: 728 SVSNFTTNNEHXXXXXXXXXXXXIMQGILQKKRELWLESAPVYVFLLDNYFLITEEIFKG 787
+ ++ + ++ G + KKR+LWL+ PVY+ LLDN LITEEI KG
Sbjct: 694 NANDDDAIQDKLALGLTYPERKLVLSGTVYKKRDLWLDPTPVYIALLDNCLLITEEISKG 753
Query: 788 SGKKYKLIERPIPIDYLSVETKEDINYKRKSLSDADEES-----CNVQTPSTSKKPPLLP 842
+KYKLIERPIPIDYLS+E ++ ++ L + ++ N TP S +P L
Sbjct: 754 ETQKYKLIERPIPIDYLSLEKRKIPGTSKQPLRNYSQKEHKSPMHNFSTPINSMRPLLKS 813
Query: 843 AGTTMSSIPKTIY--QXXXXXXXXXXXXEESSYSFKIRNTASNESHTFSTSTMEEREHWV 900
+G MS T Y + +SFKIRNTA+ ES F T + E W+
Sbjct: 814 SGNHMS----TAYGDRKTSNTEISNANPNTDEFSFKIRNTATGESFKFFTESAEVLNQWI 869
Query: 901 ASLVKAFQNHMGHNEKQAFQLQCLCDLFSYDEIQAPTNLPLEPEGSAVSSAMKEF-YSVN 959
+++++F+ + +++ AF+ L F+Y + AP NLP+ PEGS + A+K + N
Sbjct: 870 DAIMESFKRNAENHDLNAFEFTVLSSEFAYFDKDAPVNLPVAPEGSEIDVALKAYAQKAN 929
Query: 960 SPKTFASMKGDILCSVSFQYENETFLLCSVNHGVYITL-PRLLHQWKRILNFSKVTKMEI 1018
S ILC ++E +L + G+Y+ + +IL + V +ME
Sbjct: 930 KDSCSWSKTTRILCCEDVKFEGRIYLFVATTDGIYVKYRDDYGSGFVKILELNDVKRMEA 989
Query: 1019 STKLGLLFLLADRKLCYFNIPSLISAFYDSEQYLPDNRIVGIIIQEKITFFKMAEDFSNS 1078
+ KLGLLF+L +RKLCYFNI +++S + L +N IVG +I++K+ FFK+A+DF NS
Sbjct: 990 NVKLGLLFVLDNRKLCYFNISTVVSRYLAQGNTLDENCIVGTVIRDKVRFFKIADDFGNS 1049
Query: 1079 RHLFYERKGEIIIMTPEFDPLTKVFKFFKHYKSYKIPVSSSGLTASTVSDITILRNSFIV 1138
+HLF+ERKG+I+I+TPEFD LT K+FK YK YK+P SS+ + + + DI I R SF V
Sbjct: 1050 KHLFFERKGKIVILTPEFDQLTNQVKYFKFYKEYKLPSSSNNILNNEIEDIAIFRKSFAV 1109
Query: 1139 CSSKGAILYSDSFNEEGAFLPTTLTDTSKL------KLNHLSFRKQTEXXXXXXXXTMKM 1192
C+ K ILY DSF + G LP+ L D + LN L F+ T+ + +
Sbjct: 1110 CTKKTVILYQDSFEDNGIVLPSFLNDKDMMAHLRHPHLNSLPFKSATDSKKRPSIES--L 1167
Query: 1193 AEYVKSDILSKKTKPIACFRIDPNNFI-ICYDEAIIRINKFGEIPDWKKDILVLDFYCIG 1251
E K DI + K P+ F+I ++F + YDEA+++IN +GE+ DW+KDIL+LDF C G
Sbjct: 1168 TEEAKKDIATCKAIPVNFFQISQSSFFALVYDEAVVKINCYGEMSDWRKDILLLDFCCTG 1227
Query: 1252 VSLNLGHLILAGDNLVQVYNLRFVDTGEWALNTXXXXXXXXXXXXXXTDTSQDCTSIVLT 1311
S + HLIL GDNL+Q+Y+L+ V+ L + ++ T +VL+
Sbjct: 1228 ASFHGNHLILVGDNLIQIYDLKNVEQNLGEL--VPVQIIKGKKIKLASSERREKTILVLS 1285
Query: 1312 HPNIAGRQLLLHFN 1325
HPNI RQLL+ N
Sbjct: 1286 HPNILNRQLLVACN 1299
>SPCC645.06c [T] KOG4305 RhoGEF GTPase
Length = 1275
Score = 145 bits (365), Expect = 5e-34
Identities = 194/887 (21%), Positives = 345/887 (38%), Gaps = 135/887 (15%)
Query: 449 CYSYTCWSSKGSENYR---------SQLKISEFINKSVGLWTDYWKLTPEEL--SEINPK 497
CYSY C S Y+ S L+ + +S W+ +W ++ S ++ +
Sbjct: 403 CYSYICRSRSCPSKYQCYSCRCARNSSLEFTSLPGQSSDTWSIFWNISSLNSLPSSLSKR 462
Query: 498 EVKRQSFIFDLIVLEERSLNLANAAVEIYGASF---DPALLPDD--PNFKSMAYDIFIPL 552
E+ RQ+ I +LI E + N E++ A++P + +F + +
Sbjct: 463 EIARQNNIHELICKESDYVADLNTLAELFRDGIVQQQDAIVPSNRVADFIQSVFGNVESI 522
Query: 553 IELHKDILLSPILWKLKIKGKFIDGVGKIYLKWANDAKQVYVKYAQNMATVHEIINWEKE 612
+LH + L ++ + +++G + +G I L+W + AK Y+ YA+ E E +
Sbjct: 523 RQLHSRLFLPQLIMRERLQGPVVSIIGDILLEWIHAAKSSYINYAKQFPLADETYKLECQ 582
Query: 613 NNTRFASWLRQIDESTPITRSKLYHDVIFFGGFFKSLQNMPVTLRSVLKCTDPSMDDHEY 672
NT FA WL R H F + LQ + L ++LK T+ S D +
Sbjct: 583 RNTYFARWLAACRSDPRCRRLDFQH---FLQRPTQRLQRYTLELDTILKHTEQSSWDFQL 639
Query: 673 LRMAIQEIEQLSRLVDKAHGDAIDKRKIVRLARQLIFTSKTGNTVNYLNIQSGNDSVSNF 732
+ A++E+ D ++ +I L+ QL+F
Sbjct: 640 ITQAVKELRATCEECDAVIATVLEANRIRDLSYQLLFK---------------------- 677
Query: 733 TTNNEHXXXXXXXXXXXXIMQGILQKKRELWLESAPVYVFLLDNYFLITE--EIFKGSGK 790
N+E +GI+Q++ + L+ +++FLLDNY ++ + + + +
Sbjct: 678 --NHESVNLELRDPEREFFFEGIVQRRSDSRLDWLDIHLFLLDNYLIMAKARKDKRTNAS 735
Query: 791 KYKLIERPIPIDYLSVETK-EDINYKRKSLSDADEESCNVQTPSTSKKPPLLPAGTTMSS 849
+Y + +RPIP+D L + K +D K + + N+ S + K
Sbjct: 736 RYVVSKRPIPLDLLVLSPKMDDFQLKSNTNKFLGSLAGNLPQESLTTKSKRKSKVNLELM 795
Query: 850 IPKTIYQXXXXXXXXXXXXEESSYSFKIRNT-ASNESHTFSTSTMEEREHWVASLVKAFQ 908
T + + Y F IR+ A S+T +++ R+ WV + A +
Sbjct: 796 FDATAEKNNENSMNSAVFEKSQLYPFTIRHLGAYTASYTLYVESLQLRKLWVEKINVAKK 855
Query: 909 NHMGH-NEKQAFQLQCLCDL-FSYDEIQAPT-NLPLEP-------EGSAVSSAMKEF--- 955
H N K F L+ + D+ F Y N PL EGS++ A+ E
Sbjct: 856 RHSQKINIKNPFALKVVSDVAFQYPPSDLVNGNEPLNSFNEITLVEGSSIDRALNEVAWK 915
Query: 956 YSVNSPKTFAS--MKGDILCSVSF-QYENETFLLCSVNHGVYITL---PRLLHQWKRILN 1009
+ + S + GDI C F YE +L + + G+++ + WK+I +
Sbjct: 916 HPIVSEELLPEPIAYGDISCIAQFNDYEGHVSVLIATSTGIFLGAFGDSSDIRDWKKISS 975
Query: 1010 FSKVTKMEISTKLGLLFLLADRKLCYFNIPSLISAFYDSEQYLPDNRIVGII-IQEKITF 1068
+VT++ + + +L L D+ L + +I E L +++I +I ++F
Sbjct: 976 QRRVTQLGVVEEFDILLELRDKTLYAHKLSRII------EMGLIESKIAVVIGTPHAVSF 1029
Query: 1069 FKMAE-----DFSNSRHLFYERKG-----EIIIMTPEF---DPLTKVFKFFKHYKSYKIP 1115
FK+ + R L + ++G II P K + F + +
Sbjct: 1030 FKIGKLSEGASVKRERTLVFYKEGLGNTTTIICCEPVIGLGHNYQKTYAFKRKDVTSFRT 1089
Query: 1116 VSSSGLTASTVSDITILRNSFIVCSSKGA-ILYSDSFNEEGAFLPTTLTDTSKLKLNHLS 1174
+ +TA+ S I + S +C +KG +L D G P+ L DT
Sbjct: 1090 LDDFHVTANCHS-IDCFKYSIALCHNKGIDVLRLDPKLAVGFPSPSVLNDT--------L 1140
Query: 1175 FRKQTEXXXXXXXXTMKMAEYVKSDILSKKTKPIACFRI-DPNNFIICYDEAIIRINKFG 1233
FR + +KP+ FRI DP+ F CY + +N G
Sbjct: 1141 FRNRI-----------------------NNSKPLGVFRIHDPSLFACCYQFGAVFVNGEG 1177
Query: 1234 EIPD---WKKDILVLDFYCIG----VSLNLGHLILAGDNLVQVYNLR 1273
+ + W F IG V+ G+LI D V+++N R
Sbjct: 1178 SMVNKECW--------FDWIGKPNSVTSCHGYLIAFNDEFVEIWNTR 1216
>SPAC1006.06 [T] KOG4305 RhoGEF GTPase
Length = 1158
Score = 69.3 bits (168), Expect = 4e-11
Identities = 85/405 (20%), Positives = 166/405 (40%), Gaps = 57/405 (14%)
Query: 425 GVFTDLLPCYSYSHIYDDPTTDLKCYSYTCWSSKGSENYRSQLKISEFINKSVGLWTD-- 482
GVFT L CYS + + + CYS +C + + R LK+ ++ TD
Sbjct: 369 GVFTLLTECYSSTC-----SRNRLCYSISC-PRRLEQQARLHLKVQPVLSGGSTSITDKQ 422
Query: 483 -----YWK--LTPEELSEINPKEVKRQSFIFDLIVLEERSLNLANAAVEIYGASFDPALL 535
W + + + +I+ +E KRQ IF++I E + + + + +
Sbjct: 423 EEDHRLWSENVPKQVVDQIDVREWKRQEIIFEVIYTERDFVRDLEYIRDFWIKPLSTSNV 482
Query: 536 PDDPNFKSMAYDIFIPLIELHK-DILLSPILWKLKIKGKFIDGVGKIYLKWANDAKQVYV 594
+ N + +F ++++H + LS L + + ++ +G ++L + + ++
Sbjct: 483 IPENNRQQFIRCVFHNIMQIHAVNSRLSNALNRTQTLQPVVNTIGDLFLDYVPKFEP-FI 541
Query: 595 KYAQNMATVHEIINWEKENNTRFASWLRQIDESTPITRSKLYHDVIFFGGFFKS----LQ 650
KY N A EK N FA+++ +++ + +L G+ L
Sbjct: 542 KYGANQAIAKFEFEREKSTNRNFANYVHEVERLRESRKLEL-------NGYLTKPTTRLA 594
Query: 651 NMPVTLRSVLKCTDPSMDDHEYLRMAIQEIEQ-LSRLVDKAHGDAIDKRKIVRLARQLIF 709
P+ L VLK TD D E + I+ I + L++L
Sbjct: 595 RYPLLLSGVLKYTDKDNPDTENIPRVIEMIREFLTKL----------------------- 631
Query: 710 TSKTGNTVNYLNIQSGNDSVSNFTTNNEHXXXXXXXXXXXXIMQGILQKKRELWLESAP- 768
+TG T N L++ N+ +S + + I +G+++ K +
Sbjct: 632 NYETGKTENRLSLLQLNEQLS--CSPADRAKLTLFDPSRLLIFKGVVKLKASSYSNGDTE 689
Query: 769 --VYVFLLDNYFLITEEIFKGSGKKYKLIERPIPIDYLSVETKED 811
+++FLLDN+ L+ + + + +KL RP+P++ LS+ ED
Sbjct: 690 NDIHMFLLDNFLLLCKIKIQMKRRVHKLHLRPLPLELLSISYIED 734
>YLR371w [T] KOG4305 RhoGEF GTPase
Length = 1356
Score = 68.9 bits (167), Expect = 5e-11
Identities = 91/437 (20%), Positives = 176/437 (39%), Gaps = 60/437 (13%)
Query: 422 DTQGVFTDLLPCYSYSHIYDDPTTDLKCYSYTCWSSKGSENYRSQLKISEFINKSVGL-- 479
+ GVFT L CYS + T D CYS +C + + R LK + + +++ +
Sbjct: 578 NVNGVFTLLAECYSPTC-----TRDALCYSISC-PRRLEQQARLNLKPNGGLKRNISMAL 631
Query: 480 ---------WTDYWKLTPEELSEINPKEVKRQSFIFDLIVLEERSLNLANAAVEIYGASF 530
WT ++ E+ + KE+KRQ I+++ + E+ + + + +
Sbjct: 632 DDDDEEKPSWTS--SVSKEDWENLPKKEIKRQEAIYEVYITEKNFVKSLEITRDTFMKTL 689
Query: 531 DPALLPDDPNFKSMAYDIFIPLIELHK-DILLSPILWKLKIKGKFIDGVGKIYLKWANDA 589
+ K+ +F + +++ + L + + G+G I L++
Sbjct: 690 AETNIISADIRKNFIKHVFAHINDIYSVNRRFLKALTDRQRSSPVVRGIGDIVLRFI-PF 748
Query: 590 KQVYVKYAQNMATVHEIINWEKENNTRFASWLRQIDESTPITRSKLYHDVIFF--GGFFK 647
+ +V Y + +I ++ N FA + + S L H + F G +
Sbjct: 749 FEPFVSYVASRPYAKYLIETQRSVNPYFARF------DDDMMSSSLRHGIDSFLSQGVSR 802
Query: 648 SLQNMPVTLRSVLKCTDPSMD--DHEYLRMAIQEIEQLSRLVDKAHGDAIDKRKIVRLAR 705
+ M + ++ ++K TDP D D+E L A+ + + +D+A G A D+ + L +
Sbjct: 803 PGRYM-LLVKEIMKSTDPEKDKSDYEDLSKAMDALRDFMKRIDQASGAAQDRHDVKLLKQ 861
Query: 706 QLIFTSKTGNTVNYLNIQSGNDSVSNFTTNNEHXXXXXXXXXXXXIMQGILQKKRELWLE 765
+++F ++ Y+N+ N+E +GIL +K +
Sbjct: 862 KILFKNE------YVNLG----------LNDERRKIKH---------EGILSRKELSKSD 896
Query: 766 SAPV---YVFLLDNYFLITEEIFKGSGKKYKLIERPIPIDYLSVETKEDINYKRKSLSDA 822
V +LLDN L + ++K+ +RPIP+ L ED+ RK + D
Sbjct: 897 GTVVGDIQFYLLDNMLLFLKAKAVNKWHQHKVFQRPIPLPLLFACPGEDMPALRKYIGDH 956
Query: 823 DEESCNVQTPSTSKKPP 839
+ S V P + P
Sbjct: 957 PDCSGTVIQPEYNTSNP 973
>SPCC645.07 [T] KOG4305 RhoGEF GTPase
Length = 1334
Score = 56.6 bits (135), Expect = 3e-07
Identities = 101/454 (22%), Positives = 180/454 (39%), Gaps = 69/454 (15%)
Query: 406 DDPETGNQITIIIAGLDTQ---GVFTDLLPCYSYSHIYDDPTTDLKCYSYTCWSSKGSEN 462
+D E+G +I+ G DT G+FT L CYS + D P CYS +C + +
Sbjct: 524 EDNESGTRISPSTLG-DTSFPNGIFTLLTHCYSPTCAKDHP-----CYSISC-PRRLEQQ 576
Query: 463 YRSQLKISEFINKSVGLWTD------YWKLTPEELS-EINPKEVKRQSFIFDLIVLEERS 515
+R K+ +S L D + P+E++ ++ +E KRQ I ++I E
Sbjct: 577 HRLFAKMRANTEQSSSLAFDDKEQKLWIHSVPQEIAYSVSDRERKRQEVICEVIYTERDF 636
Query: 516 LN----LANAAVEIYGASFDPALLPDDPNFKSMAYDIFIPLIELHK-DILLSPILWKLKI 570
+ L + ++ AS + +P+ K + +F+ +E+ + L+ L K +
Sbjct: 637 VKDLEYLRDYWIKPLWAS---SCIPERKKEKFIR-TVFLNALEVQAVNSKLAEALTKRQN 692
Query: 571 KGKFIDGVGKIYLKWANDAKQVYVKYAQNMATVHEIINWEKENNTRFASWLRQIDESTPI 630
+D + I+L+ + +++Y EK +N FA ++ ++
Sbjct: 693 YKPIVDNIADIFLEHVPKFEP-FIRYGAGQLYGKYEFEKEKSSNPAFAKFVSDVERLKES 751
Query: 631 TRSKLYHDVIFFGGFFKS----LQNMPVTLRSVLKCTDPSMDDHEYLRMAIQEIEQLSRL 686
+ +L G+ L P+ L +VLK TD D + + I +
Sbjct: 752 RKLEL-------NGYLTKPTTRLARYPLLLEAVLKYTDEGNPDKQDIPKVINIVRGFLSR 804
Query: 687 VDKAHGDAIDKRKIVRLARQLIFTSKTGNTVNYLNIQSGNDSVSNFTTNNEHXXXXXXXX 746
++ G A +K + L +QL+F K G EH
Sbjct: 805 LNVESGKAENKFNLFHLNQQLVF--KPG----------------------EHYDLHLLDA 840
Query: 747 XXXXIMQGILQKKRELWLES---APVYVFLLDNYFLITEEIFKGSGKKYKLIERPIPIDY 803
I +G L+K+ S + V +FL D+ LI + + K+ +RPIP+
Sbjct: 841 NRQLIFKGPLKKRSAGSTSSESASDVTLFLFDHALLIVKPKTINKRELLKVFQRPIPLLL 900
Query: 804 LSVETKED----INYKRKSLSDADEESCNVQTPS 833
L + +D I Y K A ++ N + PS
Sbjct: 901 LQLFLVDDNGLRIPYSSKQQLAAVSKAANGKPPS 934
>YGR070w [T] KOG4305 RhoGEF GTPase
Length = 1155
Score = 56.2 bits (134), Expect = 3e-07
Identities = 88/437 (20%), Positives = 182/437 (41%), Gaps = 66/437 (15%)
Query: 425 GVFTDLLPCYSYSHIYDDPTTDLKCYSYTCWSSKGSENYRSQLKISEFINKSVGLWTD-- 482
GVF L CYS + + + CYS +C ++ + LK+ + +++ L D
Sbjct: 386 GVFVPLTHCYSSTC-----SLEKLCYSISC-PNRLQQQANLHLKLGGGLKRNISLALDKE 439
Query: 483 ------YWKLTPEELSE-INPKEVKRQSFIFDLIVLEERSLNLANAAVEIYGASFDPALL 535
+ P+ + E ++ +++KRQ I++L E++ + ++EI +F LL
Sbjct: 440 DDERISWTNSVPKSVWESLSKQQIKRQEAIYELFTTEKKFVK----SLEIIRDTFMKKLL 495
Query: 536 -----PDDP--NFKSMAYDIFIPLIELHKDILLSPILWKLKIKGKFIDGVGKIYLKWAND 588
P D NF + + ++++ L + L + + G+ I+L++
Sbjct: 496 ETNIIPSDVRINFVKHVFAHINEIYSVNREFLKA--LAQRQSLSPICPGIADIFLQYL-P 552
Query: 589 AKQVYVKYAQNMATVHEIINWEKENNTRFASWLRQIDESTPITRSKLYHDV-IFFGGFFK 647
++ Y + +I ++ N FA R DE ++ S L H + F
Sbjct: 553 FFDPFLSYIASRPYAKYLIETQRSVNPNFA---RFDDE---VSNSSLRHGIDSFLSQGVS 606
Query: 648 SLQNMPVTLRSVLKCTDPSMD-DHEYLRMAIQEI-EQLSRLVDKAHGDAIDKRKIVRLAR 705
+ +R ++ +DP D D + M +Q++ + L + +D+A G A D+ + L +
Sbjct: 607 RPGRYSLLVREIIHFSDPVTDKDDLQMLMKVQDLLKDLMKRIDRASGAAQDRYDVKVLKQ 666
Query: 706 QLIFTSKTGNTVNYLNIQSGNDSVSNFTTNNEHXXXXXXXXXXXXIMQGILQKKRELWLE 765
+++F ++ Y+N+ N+ +H +G+L +K +
Sbjct: 667 KILFKNE------YVNLGLNNEK-----RKIKH--------------EGLLSRKDVNKTD 701
Query: 766 ---SAPVYVFLLDNYFLITEEIFKGSGKKYKLIERPIPIDYLSVETKEDINYKRKSLSDA 822
S + +LLDN L + ++ + +RPIP+ L + ED+ ++ +++
Sbjct: 702 ASFSGDIQFYLLDNMLLFLKSKAVNKWHQHTVFQRPIPLPLLFICPAEDMPPIKRYVTEN 761
Query: 823 DEESCNVQTPSTSKKPP 839
S V P P
Sbjct: 762 PNCSAGVLLPQYQTSNP 778
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,834,881
Number of Sequences: 60738
Number of extensions: 3233796
Number of successful extensions: 7907
Number of sequences better than 1.0e-05: 6
Number of HSP's better than 0.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 7883
Number of HSP's gapped (non-prelim): 11
length of query: 1328
length of database: 30,389,216
effective HSP length: 118
effective length of query: 1210
effective length of database: 23,222,132
effective search space: 28098779720
effective search space used: 28098779720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)