ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0754 good T KOG1998 Signal transduction mechanisms Signaling protein DOCK180
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0754 246019 240200 -1940
(1940 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR422w [T] KOG1998 Signaling protein DOCK180 1272 0.0
7301710 [T] KOG1998 Signaling protein DOCK180 161 8e-39
Hs4503355 [T] KOG1998 Signaling protein DOCK180 141 9e-33
Hs20546502 [T] KOG1998 Signaling protein DOCK180 132 5e-30
Hs7662264 [T] KOG1998 Signaling protein DOCK180 130 2e-29
CE24779 [T] KOG1998 Signaling protein DOCK180 120 2e-26
Hs20538507 [T] KOG1998 Signaling protein DOCK180 111 1e-23
Hs8923210 [T] KOG1997 PH domain-containing protein 74 2e-12
Hs21389541 [T] KOG1997 PH domain-containing protein 65 8e-10
Hs18601117 [T] KOG1997 PH domain-containing protein 59 6e-08
At4g16340 [T] KOG1997 PH domain-containing protein 57 3e-07
Hs22046914 [T] KOG1997 PH domain-containing protein 55 1e-06
>YLR422w [T] KOG1998 Signaling protein DOCK180
Length = 1932
Score = 1272 bits (3291), Expect = 0.0
Identities = 724/1856 (39%), Positives = 1077/1856 (58%), Gaps = 71/1856 (3%)
Query: 28 WIPTDRLIPGTVARAFLPLKKCPELVLKSSDYVDLYPGDEVFVMEQTKDGKWCRGYVSND 87
W+PTDRLI G + ++FLPL++ PELV ++S+Y ++Y G EV+V E++ D KWCR Y
Sbjct: 9 WLPTDRLIYGVLVKSFLPLQRYPELVYENSNYANVYVGAEVYVFEESVDKKWCRAYQCLR 68
Query: 88 LMPIDFMSNMGSVTDNLPKQKIQRVIFPRRFVHLDFDEQIENYAFLRFPTGTELEQQDGR 147
P +F+SNM S D LP K + VIFPR++VH + ++ + F + P+ + + +
Sbjct: 69 PFPEEFISNMNSANDVLPDVKPKVVIFPRKYVHFEAEKAVSTMPFFKAPSAEDFKPLISK 128
Query: 148 LKKLPSLYQLMRASKVS-------RETP-PPYPFFVANGYALNREILLNLFTLTKHIYYL 199
+ S + S R+TP PP+PFF + E+ L ++ H+Y +
Sbjct: 129 ECESRSFCDSLYVSSTDDISTGKPRKTPRPPFPFFRYQKRSFKDEMGPILSLISSHVYSM 188
Query: 200 YSFGEFEIVDQMVDLYYKLDAVRIQLQANFMATNERSLIMKKATALMSIFSKFIAS-HSV 258
YS GEF I +M+ LYY LD +R +L N E+ +++ AT+L + +KF++S +
Sbjct: 189 YSIGEFSIYRKMIKLYYDLDTIRFRLSMNLTTEAEKINLIRAATSLRTKIAKFLSSTYRK 248
Query: 259 TKKIGSLQKRNRIDPFGFESILTRDQATGKLLTDSVSP-QLMATSTSLYAMTTNYPVSNA 317
K I + RN DP+GFE I RD TG+LL+ + + + +S+ L +T N+P
Sbjct: 249 NKLIANSTPRNP-DPYGFEGIFARDIDTGELLSYEIDKLRTLVSSSMLCGLTNNFPTVPV 307
Query: 318 NDLKLKPDENTKFKSFPPSQILVDCQEII-GTLVSDQHAEALTAYLYLRTAKEVLTEPFL 376
+ + N F + S ILV+ +++ +SD + L+ +YLRT EVLTE F
Sbjct: 308 VESDDESSSNGLFGTVR-SSILVNLKDLAWDPSISDPKYQDLSICVYLRTKDEVLTESFT 366
Query: 377 IDLKKNNQKSMDNVSAALFRNLPYNIGENNRVYL----------XXXXXXXXXXXXXXXX 426
+ N + ++D + A LF+N+ I N+VYL
Sbjct: 367 MTKSSNMESALDEIPAMLFKNILETIVHKNKVYLVVVLKETIAITTETAPEISSYNISTE 426
Query: 427 XQKFVKPFVPFAASADDITGSIRRGVVAGATDISRVFSKEKGSLASGHAYNFKVELFASF 486
PF PF +S ++ +++G+ AG +IS VF G + A F + L++S
Sbjct: 427 ESSSHSPFSPFNSSTENKIDHVKKGLAAGVINISPVFKFYNGLSVANKAQRFNLYLYSSD 486
Query: 487 YTDSKSEQPPIPAATLTDPAKLAKLMKAKSNVSTKNNGWGDLIDRIINDSHTGIAVTGQM 546
+DS++ + +K A L GWG LI++II DS G++V +
Sbjct: 487 SSDSQN----------FNSSKDADL------------GWGGLINKIIKDSSEGVSVNPRA 524
Query: 547 ESLVVSVKEIKEDCKFLQTNSDNAMAITAVNPIFYDTLEQKQTDRIYLTLDKVSICGLEN 606
SL V+VKEI + + S + + I ++ FYDT+ Q +RIYL L +VS+ GL
Sbjct: 525 VSLSVTVKEIIGKQEAEKVLSTSLVPIRSIPTYFYDTMFS-QAERIYLNLGRVSLYGLPA 583
Query: 607 KKSNVSNITIQISSNNDKITFRPSSVTHSYKKWAFITVRPGELVNETIRIDGIDSMTKEE 666
+N+ N+T+QIS N + F + + W F++VRP E + E+IRI+G+++M ++E
Sbjct: 584 ADTNIENVTVQISCRNKAVKFCKNKLEERSGDWKFVSVRPNESIGESIRIEGVENMNEDE 643
Query: 667 TLRVSAYLNGRLFAKSRFYVKKGLQILEYKKKSVFQLISSLGKPLVEIEVGTRYVGNNYN 726
TLRV YLNG L AKS ++KK +I+EY+K +VFQ++SS PL+ +E+ Y G YN
Sbjct: 644 TLRVLVYLNGFLMAKSNIHIKKKNEIIEYRKGTVFQIMSSKSVPLIHLELEASYFGRRYN 703
Query: 727 MDRTVHSLLSLLRKHQITENDFEQKSLEALKSLKMVSIKQITKYFNPIXXXXXXXXYYTC 786
++ + + L L K+ + ++ LK L VS K + K+F+ I +Y
Sbjct: 704 INPAITNFLVLQTKNVEFDQQLKEHYSVTLKQLNNVSFKDLLKHFDTILA------HYLL 757
Query: 787 YRHAARS-------SEALKKAVFSSLVQFLDMNIARHDNYKHLFNDFFEEVERENSNYLP 839
+ S +L VFS V+FL++ + +N ++ FN +++V + P
Sbjct: 758 LLESVNEATDKKGPSSSLPNIVFSEFVKFLNLMLTHQENSRYWFNRLYKKVMSKELE-CP 816
Query: 840 ELGPILVRLMSEQFSSSANSWSYVGRALCRS--YILLLKLGRLFSKDIVGYHQAVDEFFN 897
+ PIL++ M+ F S +SW+ G A+CR+ YI++L +G S ++ + FF
Sbjct: 817 NVAPILIKHMTTIFDRSHSSWTRTGTAICRTILYIIVLAIGSSHSDEMPNF----SHFFR 872
Query: 898 SLSIFFRVTNDSVLVDQVTILETYDLAINETSAIFDDPHLIQLVLLLFNACQEKENSIEF 957
SL F + ++ ++ DQ+ ++E+ + + L++ + LF CQEKE + +
Sbjct: 873 SLHKFLMLADEPIMADQILLIESIPSMLETMTNHCKVEDLVRFAIGLFECCQEKEMNQKM 932
Query: 958 SQDDLSTKEKNFVNAKYLLLRRILQNPELAPFFKDPAE-NPLRTKFLGQVIEWCFKPFIK 1016
LS +E+ ++N K+ L +++ L + + + LR +FL + +EW P+
Sbjct: 933 YSRPLSVREEEYLNTKFNCLLKLINKKVLQNYLTNTESVDKLRLQFLSKTLEWLLTPYTP 992
Query: 1017 EKGCVPNLTTASYANGVLITIIEQAQDTVFKRNLIRLLPIFCRIFLFLRSACEKEDCFKF 1076
++ + N V ITIIE + + +RNLIRLLP C+ F+ LR C+K +
Sbjct: 993 GDDKCFHVESLRLVNSVFITIIEDYKFDMLQRNLIRLLPYLCKSFVHLRRYCKKARLMRP 1052
Query: 1077 KRVFAPLFPTVTPLPEITVDSMVTDEVFVGVLLETATIIIALTKIVEQQYDSHGSFIKAI 1136
+RVF LFP P I VDS+V DEV V VLLE A II +TKI ++ S+ SF + I
Sbjct: 1053 RRVFTMLFPREIPCNYIPVDSIVNDEVVVEVLLELAIIICEITKIASSRFPSYQSFSEII 1112
Query: 1137 EACREDEDFQSPYYVTKIVREDLATIFVTIHRLIKGDFFPSKKWFTMTAAIMRACMTLSE 1196
C +D FQS +Y +I E++ TI T+ K D+FP KW ++A + R+ + L
Sbjct: 1113 NLCDKDTLFQSNFYSRQITNENVYTITKTVFLFFKQDWFPGMKWLGVSALLGRSSLILLS 1172
Query: 1197 MCLDVFKLYYVPDEQCTLET-FDAELWGRYFKLVLCIANHKTVNSTPLAPLPRKAVYLVT 1255
+C D P E D LW Y K++L ++NHK+ + T LA PRKAVYL++
Sbjct: 1173 LCKDYIIENNSPSPSKESEKRVDMRLWAEYVKVILLVSNHKSASLTKLAITPRKAVYLIS 1232
Query: 1256 GDLIGRASYILEQIWDILGDNCIGTDLDNKYGILRSSVYQMTFLTAAMDIVTDFCAFSFL 1315
GDL ++YIL + WD L KYG+ S Q ++ + F+F
Sbjct: 1233 GDLKKISAYILNECWDALATGHYNITYAKKYGLGALSDCQFELFVHNQFLIREIFIFAFH 1292
Query: 1316 RHVDARRVGSKIIWVVLILVWTNENSLTTAIEELTPQFFNAYQKGALRPTVFEVEIFLDT 1375
RH+DA R+ KI+W + + W SL A+ P+ F+AYQ G LR +E+E F+
Sbjct: 1293 RHIDATRICCKILWGLGLNFWRIFGSLQPAVNACIPELFSAYQIGKLRLNDYELERFVSC 1352
Query: 1376 LLHVIHLDTEDSIKDTLFNYVRFLKEFLLSLAETEDIPSGEEFDDDRTASQLRIFGYLMS 1435
L ++H+ D+ +++R L FL + E IP+ EEFDDDRTA + +F YL+
Sbjct: 1353 LFFMMHVPDSDTFFPACMDFLRDLLGFLHIVNEIYKIPNQEEFDDDRTARHIEMFEYLLE 1412
Query: 1436 MKRPEMLHTLVNDLFINHMRRKDYIQAALSLELLALTYEWNPNDSLPATKYPPLPEQSSF 1495
RPE+ H ++ DLFI+ +++KD++QAALSLELLA TY W+ ND+L A +PPLPEQSSF
Sbjct: 1413 ANRPELFHKMIYDLFIHFIQKKDFVQAALSLELLAGTYAWDSNDTLEAISFPPLPEQSSF 1472
Query: 1496 ERREYLYKEAARNFTKGLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQN 1555
ER+EYL KE+ARNF++G K EKAL VYKDL AYD+INYDL+GL++VH QI+ IYT LQ+
Sbjct: 1473 ERKEYLLKESARNFSRGQKPEKALAVYKDLIKAYDEINYDLNGLAFVHDQIAGIYTRLQS 1532
Query: 1556 VDRLVPNYFKVSFYGYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGSKLVNSFTEA 1615
+DRLVP YFKVSF G+GFPK+LR K+FVFEGLPFEHITS+H+RLL+ Y GS +V+S E
Sbjct: 1533 IDRLVPTYFKVSFMGFGFPKSLRNKSFVFEGLPFEHITSMHDRLLRSYHGSNIVHSQEEV 1592
Query: 1616 DKLLVSPPNGKFIHVISVEPRLQISDEYATSDKKND-NNKVRLYVENRDLKTFSSSRRVA 1674
D LL++PP GK+IHV SVEP L ISD Y +SDKK+ NNKVR+Y+ENRDL+TFS+SRR+
Sbjct: 1593 DMLLMNPPMGKYIHVASVEPCLSISDNYNSSDKKSSINNKVRMYIENRDLRTFSNSRRLP 1652
Query: 1675 GTHGITDLWVIEYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQELSGLED 1734
G G+TDLWV EY + T +TFPTLMNRSE+VKVT+ +LSP+ NAI+SLQ KIQEL GLE+
Sbjct: 1653 GAKGVTDLWVEEYTYHTMNTFPTLMNRSEIVKVTKSKLSPLENAIRSLQVKIQELYGLEN 1712
Query: 1735 MCYKLMKENGDCSEVFSELSRNITGTIDAPINGGIAEYRVFYTDEETKSKLDPADVELLV 1794
MC K +K++GD +++F+ELS NITGTI AP+NGGI++Y+ F + T + D+ L
Sbjct: 1713 MCNKTLKDHGDVNDLFTELSTNITGTISAPVNGGISQYKAF-LEPSTSKQFSTDDLGRLT 1771
Query: 1795 AAFNELTIVLNRCLALHGQLCPI-SLSKSHTLLKDLFAKNFEKEIKVSGIDINETN 1849
AF+EL VL RCL LH +L P L SH LL LF +NF +EI+ ++E N
Sbjct: 1772 LAFDELVAVLGRCLTLHAELLPSKDLKPSHDLLVRLFEENFAEEIERYSRTLSEAN 1827
>7301710 [T] KOG1998 Signaling protein DOCK180
Length = 2015
Score = 161 bits (408), Expect = 8e-39
Identities = 174/758 (22%), Positives = 318/758 (40%), Gaps = 86/758 (11%)
Query: 1105 VGVLLETATIIIALTKIVEQQYDSHGSFIKAIEACREDE-----DFQSPYYVTKIVREDL 1159
+G+L+ T +II+ + V Q S + ++ E D SP + ++E L
Sbjct: 769 LGILIRTISIIMEGSNAVLPQLVS--CLLGLLQLLDETHYKRYWDELSPNKDPRDLKEFL 826
Query: 1160 ATIFVTIHRLIKGDF--FPSKKWFTMTAA---IMRACMTLSEMCLDVFKLYYVPDEQCTL 1214
+ + L+ D+ FP+ W M A ++R M+L E + + P
Sbjct: 827 SKSLLVYEELLTQDWHVFPND-WLVMKLAANDVLR--MSLEEFAKPLVYRFLGP------ 877
Query: 1215 ETFDAELWGRYFKLVLCIANHKTVNSTPLAPLPRKAVYLVTGDLIGRASYILEQIWDILG 1274
+ FD++LW YF L + ++ R + GD+ + + +W LG
Sbjct: 878 QAFDSQLWWSYFSLAVAFLTQPSLQLEQYREPKRLKILHSHGDMRVLMGFQILSMWSQLG 937
Query: 1275 D-------NCIGTDLDNKYGILRSSVYQMTFLTAAMDIVTDFCAFSFLRHVDARRVGSKI 1327
+ + +G L+ + V + A + + D R V S++
Sbjct: 938 EQKLHFIPSMVGPFLEV------TLVPEPALRKATLSVFYDMMQCEQAARGSFRLVESEL 991
Query: 1328 IWVVLILVWTNENSLTTAIEELTPQFFNAYQKGALRPTVFEVEIFLDTLLHVIHLDTEDS 1387
I + +L+ N+ + Y+ E+F LL + ++ +
Sbjct: 992 IDKLDLLISENKGD-------------DEYR-----------ELFSTILLEKVQVENPNW 1027
Query: 1388 IKDTLFNYVRFLKEFLLSLAETEDIPSGEEFDDDRTASQLRIFG-YLMSMKRPEMLHTLV 1446
K+ ++ + L L + + GEE D R + + Y + R EM +
Sbjct: 1028 -KEAGIAFIASVTRLLERLLDYRSVMQGEENRDKRMTCTVNLLNFYKNEINRKEMYLRYI 1086
Query: 1447 NDLFINHMRRKDYIQAALSLELLALTYEWNPNDSLPATKYPPLPE--QSSFERREYLYKE 1504
L H++ ++Y +A +L+L A W+ + P Q ++R+E LY E
Sbjct: 1087 YKLHNLHLQAENYTEAGFTLKLYASMLSWDRETQ----SFAPFDNSGQPEWQRKERLYHE 1142
Query: 1505 AARNFTKGLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVDRLVPNYF 1564
+ F KG EK + + K+LA Y+ +D + LS + Q + + ++ R P YF
Sbjct: 1143 ILKYFDKGKCWEKGIPLCKELAHLYETRRFDYNKLSEILIQEAKFFQNILTQLRPEPEYF 1202
Query: 1565 KVSFYGYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGSKLVNSFTEADKLLVSPPN 1624
+V FYG G P +R K FV+ GL +E I + RL +P ++++ + + D +++ P+
Sbjct: 1203 RVGFYGMGLPLFVRNKQFVYRGLEYERIGAFTQRLQTEFPSAQILGNNSPPDNAILNAPD 1262
Query: 1625 GKFIHVISVEPRLQISDEYATSDKKND-NNKVRLYVENRDLKTFSSSR-----RVAGTHG 1678
++I + +V P + D A K+ + E D+ F R V +
Sbjct: 1263 -QYIQISNVRP---VGDAQALKTAMVPVPEKIARFYEVNDVTRFIYDRPMYKGTVDKDNE 1318
Query: 1679 ITDLWVIEYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQELSGLEDMCYK 1738
LW+ I E S P ++ EV + T + L+P+ A + + +ELS L
Sbjct: 1319 FKSLWIERTILEIASPLPGILRWYEVKQKTMQELTPVEYACEIISNAGKELSEL------ 1372
Query: 1739 LMKENGDCSEVFSELSRNITGTIDAPINGGIAEYR-VFYTDEETKSKL---DPADVELLV 1794
+++ D + S + GTIDA + GGI++Y+ F++++ KS A+V+ L
Sbjct: 1373 IVQYKRDPKRNINPFSMRLQGTIDANVMGGISKYQEAFFSEQFLKSPQGAGQQANVQRLK 1432
Query: 1795 AAFNELTIVLNRCLALHGQLCPISLSKSHTLLKDLFAK 1832
E +L + L LHGQL P + H L + F++
Sbjct: 1433 VLILEQIQILEQALELHGQLAPSGVQPLHNRLLERFSQ 1470
>Hs4503355 [T] KOG1998 Signaling protein DOCK180
Length = 1865
Score = 141 bits (356), Expect = 9e-33
Identities = 155/762 (20%), Positives = 307/762 (39%), Gaps = 72/762 (9%)
Query: 1094 TVDSMVTDEVFVGVLLETATIIIALTKIVEQQYDSH-GSFIKAIEACREDEDFQSPYYVT 1152
TV SM D +G + +T I+ Q D H IK R D
Sbjct: 917 TVISMGRDSELIG------NFVACMTAILRQMEDYHYAHLIKTFGKMRTD---------- 960
Query: 1153 KIVREDLATIFVTIHRLIKGDFFPSKKWFTMTAAIMRACMTLSEMCLDVFKLYYVPDEQC 1212
V + L F+ LI + +P W M + + D+ ++
Sbjct: 961 --VVDFLMETFIMFKNLIGKNVYPFD-WVIMNMVQNKVFLRAINQYADMLNKKFLDQAN- 1016
Query: 1213 TLETFDAELWGRYFKLVLCIANHKTVNSTPLAPLPRKAVYLVTGDLIGRASYILEQIWDI 1272
F+ +LW YF L + +++ + R + GD+ + + + +W
Sbjct: 1017 ----FELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYN 1072
Query: 1273 LGDNCIGTDLDNKYGILRSSVYQMTFLTAAMDIVTDFCAFSFLRHVDARRVGSKIIWVVL 1332
LG +++ F+ ++V + + + R+ I + ++
Sbjct: 1073 LGQ------------------HKIKFIP---EMVGPILEMTLIPETELRKATIPIFFDMM 1111
Query: 1333 ILVWTNENSLTTAIEELTPQFFNAYQKGALRPTVFEVEIFLDTLLHVIHLDTEDSIKDTL 1392
+ + S E+ + + + G + ++ D +L + H + T
Sbjct: 1112 QCEFHSTRSFQMFENEIITKLDHEVEGGRGDE---QYKVLFDKIL-LEHCRKHKYLAKTG 1167
Query: 1393 FNYVRFLKEFLLSLAETEDIPSGEEFDDDRTASQLRIFGYLMSMKRPEMLHTLVNDLFIN 1452
+V+ + + L + I E ++R + + + + ++R EM + L
Sbjct: 1168 ETFVKLVVRLMERLLDYRTIMHDEN-KENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDL 1226
Query: 1453 HMRRKDYIQAALSLELLALTYEWNPNDSLP-ATKYPPLPEQSSFERREYLYKEAARNFTK 1511
H +Y +AA +L L A +W+ + + T+ + + +E LY+E F K
Sbjct: 1227 HKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDK 1286
Query: 1512 GLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVDRLVPNYFKVSFYGY 1571
G E+A+ + K+LA+ Y+ +D + LS + + + Y ++ V R P+YF V +YG
Sbjct: 1287 GKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQ 1346
Query: 1572 GFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGS-KLVNSFTEADKLLVSPPNGKFIHV 1630
GFP LRGK F++ G +E RLL +P + K+ + D + SP G++I
Sbjct: 1347 GFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSP--GQYIQC 1404
Query: 1631 ISVEPRLQISDEYATSDKKNDNNKVRLYVENRDLKTFSSSRRVA-----GTHGITDLWVI 1685
+V+P+L + ++ + + ++ + +++ F SR + + ++W+
Sbjct: 1405 FTVKPKLDLPPKF----HRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIE 1460
Query: 1686 EYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQELSGLEDMCYKLMKENGD 1745
I+ T P ++ EV V +SP+ NAI+++Q +++ + + + D
Sbjct: 1461 RTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKINSM------VQQHLDD 1514
Query: 1746 CSEVFSELSRNITGTIDAPINGGIAEY-RVFYTDEETKSKLDPAD-VELLVAAFNELTIV 1803
S + LS + G +D + GG A Y + F+TD + + + +E L
Sbjct: 1515 PSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPF 1574
Query: 1804 LNRCLALHGQLCPISLSKSHTLLKDLFAKNFEKEIKVSGIDI 1845
L + +HG +L H ++ F + EK K G+ I
Sbjct: 1575 LAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRI 1616
>Hs20546502 [T] KOG1998 Signaling protein DOCK180
Length = 1830
Score = 132 bits (332), Expect = 5e-30
Identities = 145/706 (20%), Positives = 288/706 (40%), Gaps = 73/706 (10%)
Query: 1094 TVDSMVTDEVFVGVLLETATIIIALTKIVEQQYDSHGSF-IKAIEACREDEDFQSPYYVT 1152
TV +M D + + + + +T I+ Q D H SF I+ + E DF
Sbjct: 922 TVITMGRDHILI------SHFVACMTAILNQMGDQHYSFYIETFQTSSELVDF------- 968
Query: 1153 KIVREDLATIFVTIHRLIKGDFFPSKKWFTMTAAIMRACMTLSEMCLDVFKLYYVPDEQC 1212
L F+ LI + +P W M+ M + + L + Q
Sbjct: 969 ------LMETFIMFKDLIGKNVYPGD-WMAMS-------MVQNRVFLRAINKFAETMNQK 1014
Query: 1213 TLE--TFDAELWGRYFKLVLCIANHKTVNSTPLAPLPRKAVYLVTGDLIGRASYILEQIW 1270
LE F+ +LW YF L + ++ + + GD+ + + +W
Sbjct: 1015 FLEHTNFEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMW 1074
Query: 1271 DILGDNCIGTDLDNKYGILRSSVYQMTFLTAAMDIVTDFCAFSFLRHVDARRVGSKIIWV 1330
LG N ++ F+ + + + + + + R+ I +
Sbjct: 1075 YKLGQN------------------KICFIPGMVGPILEM---TLIPEAELRKATIPIFFD 1113
Query: 1331 VLILVWTNENSLTTAIEELTPQFFNAYQKGALRPTVFEVEIFLDTLLHVIHLDTEDSIKD 1390
+++ + E+ + + + G ++ L+++L + +I
Sbjct: 1114 MMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQL---LESILMECAAE-HPTIAK 1169
Query: 1391 TLFNYVRFLKEFLLSLAETEDIPSGEEFDDDRTASQLRIFGYLMSMKRPEMLHTLVNDLF 1450
++ N+V +K L L + + + +E D+R + + + + R EM + L
Sbjct: 1170 SVENFVNLVKGLLEKLLDYRGVMT-DESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLR 1228
Query: 1451 INHMRRKDYIQAALSLELLALTYEWNPNDSLPATKYPPLPE-QSSFERREYLYKEAARNF 1509
H+ +Y +AA +L L +W+ Q+ + +E LY+ F
Sbjct: 1229 DLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQLKETLYETIIGYF 1288
Query: 1510 TKGLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVDRLVPNYFKVSFY 1569
KG E+A+++ K+LA+ Y+ +D + LS Q + Y + + R P+YF V +Y
Sbjct: 1289 DKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYY 1348
Query: 1570 GYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGSKLVNSFTEADKLLVSPPNGKFIH 1629
G GFP LR K F++ G +E +L+ +P ++ +N+ T A V G++I
Sbjct: 1349 GQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNT-TSAPGDDVKNAPGQYIQ 1407
Query: 1630 VISVEPRLQISDEYATSDKKNDNNKVRLYVENRDLKTFSSSRRV-AGT----HGITDLWV 1684
+V+P + DE+ K +++ + ++ ++ F SR V GT + +W+
Sbjct: 1408 CFTVQP---VLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDPENEFASMWI 1464
Query: 1685 IEYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQELSGLEDMCYKLMKENG 1744
F T P ++ EVV +++ +SP+ NAI+++ + E + + +
Sbjct: 1465 ERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMS------TANEKILMMINQYQS 1518
Query: 1745 DCSEVFSELSRNITGTIDAPINGGIAEY-RVFYTDEETKSKLDPAD 1789
D + + LS + G +D + GG A+Y + F+T+E + + D
Sbjct: 1519 DETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQD 1564
>Hs7662264 [T] KOG1998 Signaling protein DOCK180
Length = 765
Score = 130 bits (328), Expect = 2e-29
Identities = 107/408 (26%), Positives = 184/408 (44%), Gaps = 25/408 (6%)
Query: 1432 YLMSMKRPEMLHTLVNDLFINHMRRKDYIQAALSLELLALTYEWNPNDSLPATKYPPLPE 1491
Y + + EM ++ L+ H++ +++ +AA +L L EW+ P ++ P
Sbjct: 26 YKTELNKEEMYIRYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDR---PLREFLTYPM 82
Query: 1492 QSSFERREYLYKEAARNFTKGLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYT 1551
Q+ ++R+E+L+ +NF +G E + + + +A+ Y+ YD LS + +++Y
Sbjct: 83 QTEWQRKEHLHLTIIQNFDRGKCWENGIILCRKIAEQYESY-YDYRNLSKMRMMEASLYD 141
Query: 1552 DLQNVDRLVPNYFKVSFYGYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGSKLVNS 1611
+ + RL P +F+V FYG FP LR K FV G +E + + R+L +P + +
Sbjct: 142 KIMDQQRLEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQH 201
Query: 1612 FTEADKLLVSPPNGKFIHVISVEPRLQISDEYATSDKKNDNNKVRLYVENRDLKTFSSSR 1671
+ D+ + +++ + +V P + S E + DN K Y N K
Sbjct: 202 ANQPDETIFQ-AEAQYLQIYAVTP-IPESQEVLQREGVPDNIK-SFYKVNHIWKFRYDRP 258
Query: 1672 RVAGT----HGITDLWVIEYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQ 1727
GT + LWV + P + EV K +SP+ NAI+ L+ K Q
Sbjct: 259 FHKGTKDKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQ 318
Query: 1728 ELSGLEDMCYKLMKENGDCSEVFSELSRNITGTIDAPINGGIAEYR-VFYTDEETKSKLD 1786
+L L C +N + L+ + G IDA +NGG++ Y+ F+ E S
Sbjct: 319 QLKTLISQCQTRQMQN------INPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILS--H 370
Query: 1787 PADVELLVAAFNELTI----VLNRCLALHGQLCPISLSKSHTLLKDLF 1830
P D E +A EL + +L LA+H + P + H L D F
Sbjct: 371 PEDGE-KIARLRELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQF 417
>CE24779 [T] KOG1998 Signaling protein DOCK180
Length = 1781
Score = 120 bits (301), Expect = 2e-26
Identities = 118/490 (24%), Positives = 208/490 (42%), Gaps = 54/490 (11%)
Query: 1399 LKEFLLSLAETEDIPSGE--EFDDDRTASQLRIFGYLMSMKRPEMLHTLVNDLFINHMRR 1456
+ L +L E ++ S E D + +++ Y E+ + L+ H
Sbjct: 1182 IDRLLTALIEYHEVASKSLVECVDSLMSRTVQLMRYYNQYSHKELYVKYIYKLYDLHTSY 1241
Query: 1457 KDYIQAALSL--ELLALTYEWNPNDSLPATKYP-PLPEQSSFER--REYLYKEAARNFTK 1511
+ I+AA +L LT++ +D+LP L R +E L +EA F+K
Sbjct: 1242 GNKIEAAKTLLRHATMLTFD---DDALPQWLIARSLNRHRELHRQLKEDLMEEAGNLFSK 1298
Query: 1512 GLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVDRLVPNYFKVSFYGY 1571
G E AL VY L Y I D D L+ + +I+ +YT + +R Y+ V+FYG
Sbjct: 1299 GEDWEDALIVYNQLVPVYQNIIMDYDKLAGLLQKIAQLYTSISRTERAYFYYYLVAFYGQ 1358
Query: 1572 GFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGSKLVNSFTEADKLLVSPPNGKFIHVI 1631
GFP L G FVF E R++K+Y + + L+ SP G++I V
Sbjct: 1359 GFPAYLNGHKFVFRSEKLEMHGEFMQRIMKMYDNPEKIMKTDPCPHLVDSP--GRYIQVF 1416
Query: 1632 SVEPRLQISDEYATSDKKNDNNKVRLYVENRDLKTFSSSR----------RVAGTHGITD 1681
+++P I + + ++ Y +++TF S+ + +
Sbjct: 1417 NIDP---IGTGCSFENNPEVKPVIKKYFRYYNIQTFEYSKVEERKDTKWTSIDPSSEFMR 1473
Query: 1682 LWVIEYIFETKSTFPTLMNRSEVVKVTEK-RLSPINNAIKSLQQKIQELSGLEDMCYKLM 1740
W++ +T + PT + +E+V++++ ++P+ NA++ +++K +EL+ E
Sbjct: 1474 NWLVRRRIKTADSLPTDLRFTEIVELSDPIYVTPLQNAVEQMRKKNKELN--ETAASAES 1531
Query: 1741 KENGDCSEVFSELSRNITGTIDAPINGGIAEYRVFYTDEETKSKLDPADVELLVAAFNEL 1800
N D LSR+I G + A + GG+ Y VF+T E + + ++ + L
Sbjct: 1532 NPNFD----LKLLSRDILGVVSAAVMGGVKNYEVFFT--EACRNICECGEQSVIMELSSL 1585
Query: 1801 TI----VLNRCLALHGQLCPISLSKSHTLLKDLF-------AKNFEK---------EIKV 1840
I +L C +H C +T+L D F +NF K I++
Sbjct: 1586 IIEQVEILEYCCYVHASRCQGEARAINTMLADSFDSHRRYVEENFGKTRSRLPTHANIRL 1645
Query: 1841 SGIDINETND 1850
S D + ND
Sbjct: 1646 SSFDSDSIND 1655
>Hs20538507 [T] KOG1998 Signaling protein DOCK180
Length = 988
Score = 111 bits (278), Expect = 1e-23
Identities = 103/499 (20%), Positives = 205/499 (40%), Gaps = 49/499 (9%)
Query: 1111 TATIIIALTKIVEQQYDSHGSFIKAIEACREDEDFQSPYYVTKIVREDLATIFVTIHRLI 1170
T + L ++ Q D+H + ++FQS ++E L IF L+
Sbjct: 494 TGEYVSCLLSLLRQMCDTHFQHLL--------DNFQSK----DELKEFLLKIFCVFRNLM 541
Query: 1171 KGDFFPSKKWFTMTAAIMRACMTLSEMCLDVFKLYYVPDEQCTLETFDAELWGRYFKLVL 1230
K FP + W M +T + + V L + T FD ++W YF L +
Sbjct: 542 KMSVFP-RDWMVMRL------LTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAV 594
Query: 1231 CIANHKTVNSTPLAPLPRKAVYLVTGDLIGRASYILEQIWDILGDNCIGTDLDNKYGILR 1290
N ++ + RK + GD+ +Y L +W LG+
Sbjct: 595 LFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGE--------------- 639
Query: 1291 SSVYQMTFLTAAMDIVTDFCAFSFLRHVDARRVGSKIIWVVLILVWTNENSLTTAIEELT 1350
+++ F+ ++ F + + + R + I ++ + EL
Sbjct: 640 ---HKIHFIPG---MIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELI 693
Query: 1351 PQFFNAYQKGALRPTVFEVEIFLDTLL----HVIHLDTEDSIKDTLFNYVRFLKEFLLSL 1406
+ + +G + E+ L L ++ +++ ++T ++V + + L
Sbjct: 694 DKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGISFVTSVTRLMERL 753
Query: 1407 AETEDIPSGEEFDDDRTASQLRIFGYLMS-MKRPEMLHTLVNDLFINHMRRKDYIQAALS 1465
+ D GEE ++ + + + + S + + EM ++ L H++ ++Y +AA +
Sbjct: 754 LDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFT 813
Query: 1466 LELLALTYEWNPNDSLPATKYPPLPEQSSFERREYLYKEAARNFTKGLKLEKALTVYKDL 1525
L L +W + P ++ P Q+ ++R+E L ++ F KG E + + ++L
Sbjct: 814 LLLYCELLQW---EDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCREL 870
Query: 1526 ADAYDKINYDLDGLSYVHGQISNIYTDLQNVDRLVPNYFKVSFYGYGFPKNLRGKTFVFE 1585
A Y+ + YD LS++ ++ Y ++ RL P +F+V FYG FP LR K +V
Sbjct: 871 ACQYESL-YDYQSLSWIRKMEASYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCR 929
Query: 1586 GLPFEHITSVHNRLLKLYP 1604
G +E + + R+L +P
Sbjct: 930 GHDYERLEAFQQRMLSEFP 948
>Hs8923210 [T] KOG1997 PH domain-containing protein
Length = 500
Score = 73.9 bits (180), Expect = 2e-12
Identities = 76/304 (25%), Positives = 128/304 (42%), Gaps = 42/304 (13%)
Query: 1522 YKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVDRLVPNYFKVSFYGYGFPKNLRGKT 1581
+K L+D Y YD +H + + + RL Y++V+FYG GF + GK
Sbjct: 202 FKKLSDLY----YD------IHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKE 251
Query: 1582 FVFEGLPFEHITSVHNRLLKLYP---GSKLVNSFTEADKLLVSP----PNGKFIHVISVE 1634
++++ ++ + RLLKLY G+ V +++K V+P P +I V V
Sbjct: 252 YIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNK--VNPKDLDPKYAYIQVTYVT 309
Query: 1635 PRLQISDEYATSDKKND----NNKVRLYVENRDLKTFSSSRRVAGTHGITDLWVIEYIFE 1690
P +E D+K+D +N R E F+ S + G G+ + I
Sbjct: 310 P---FFEEKEIEDRKSDFEMHHNINRFVFET----PFTLSGKKHG--GVAEQCKRRTILT 360
Query: 1691 TKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQELSGLEDMCYKLMKENGDCSEVF 1750
T FP + R +V+ + L+PI AI + +K+ EL+ L M E D
Sbjct: 361 TSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTM------EEVD----M 410
Query: 1751 SELSRNITGTIDAPINGGIAEYRVFYTDEETKSKLDPADVELLVAAFNELTIVLNRCLAL 1810
L + G++ +N G Y + +E K V+LL F + + L +
Sbjct: 411 IRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDV 470
Query: 1811 HGQL 1814
+ +L
Sbjct: 471 NERL 474
>Hs21389541 [T] KOG1997 PH domain-containing protein
Length = 881
Score = 65.5 bits (158), Expect = 8e-10
Identities = 90/434 (20%), Positives = 171/434 (38%), Gaps = 55/434 (12%)
Query: 1439 PEMLHTLVNDLFINHMRRKDYIQAALS-LELLALTYEWN------PNDSLPATKYPPLPE 1491
PE+ T ++ + H++ D+ +AA+ + + AL E+ PN K P +
Sbjct: 423 PELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNID 482
Query: 1492 QSSFERREY--------------LYKEAARNFTKGLKLEKALTVYKDLADAYDKINYDLD 1537
+ + + L ++ K + E + K + Y+K + +
Sbjct: 483 EEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEK-RREFE 541
Query: 1538 GLSYVHGQISNIYTDLQNV----DRLVPNYFKVSFYGYGFPKNLRGKTFVFEGLPFEHIT 1593
L+ V+ + YT + V RL+ +F+V+FYG F + GK ++++ ++
Sbjct: 542 KLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLS 601
Query: 1594 SVHNRLLKLYP---GSKLVNSFTEADKLLVSPPNGKFIHVISVEPRLQISDEYATSDK-- 1648
+ RL+KLY G++ V ++DK+ + K+ H+ + D+ T K
Sbjct: 602 EISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTE 661
Query: 1649 -KNDNNKVRLYVENRDLKTFSSSRRVAGTHGITDLWVIEYIFETKSTFPTLMNRSEVVKV 1707
+ ++N R E ++ S + G I + I T ++FP + R +
Sbjct: 662 FERNHNISRFVFE----APYTLSGKKQGC--IEEQCKRRTILTTSNSFPYVKKRIPINCE 715
Query: 1708 TEKRLSPINNAIKSLQQKIQELSGLEDMCYKLMKENGDCSEV---FSELSRNITGTIDAP 1764
+ L PI+ A ++ K EL L CS +L + G +
Sbjct: 716 QQINLKPIDVATDEIKDKTAELQKL-------------CSSTDVDMIQLQLKLQGCVSVQ 762
Query: 1765 INGGIAEYRVFYTDEETKSKLDPADVELLVAAFNELTIVLNRCLALHGQLCPISLSKSHT 1824
+N G Y + ++ SK P V L F + + L L+ +L + H
Sbjct: 763 VNAGPLAYARAFLNDSQASKYPPKKVSELEDMFRKFIQACSIALELNERLIKEDQVEYHE 822
Query: 1825 LLKDLFAKNFEKEI 1838
LK F ++ KE+
Sbjct: 823 GLKSNF-RDMVKEL 835
>Hs18601117 [T] KOG1997 PH domain-containing protein
Length = 2047
Score = 59.3 bits (142), Expect = 6e-08
Identities = 62/243 (25%), Positives = 109/243 (44%), Gaps = 24/243 (9%)
Query: 1501 LYKEAARNFTKGLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNV---- 1556
L ++AA FT G E VYK+L + + D L+ VHG++ +T + +
Sbjct: 1686 LLEQAAGYFTMGGLYEAVNEVYKNLIPILEA-HRDYKKLAAVHGKLQEAFTKIMHQSSGW 1744
Query: 1557 DRLVPNYFKVSFYGYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYP---GSKLVNSFT 1613
+R+ YF+V FYG F +L + FV++ + + +RL + Y G +V
Sbjct: 1745 ERVFGTYFRVGFYGAHFG-DLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIK 1803
Query: 1614 EADKLLVSPPNGK--FIHVISVEPRLQISDEYATSDKKNDNNKVRLYVENRDLKTF---S 1668
+++ + S + + +I + VEP D Y D+ V + N L+TF +
Sbjct: 1804 DSNPVDKSKLDSQKAYIQITYVEPYF---DTYELKDR------VTYFDRNYGLRTFLFCT 1854
Query: 1669 SSRRVAGTHG-ITDLWVIEYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQ 1727
HG + + + + T FP + R V E L+P+ AI+ +Q+K +
Sbjct: 1855 PFTPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTR 1914
Query: 1728 ELS 1730
EL+
Sbjct: 1915 ELA 1917
>At4g16340 [T] KOG1997 PH domain-containing protein
Length = 1120
Score = 57.0 bits (136), Expect = 3e-07
Identities = 74/324 (22%), Positives = 131/324 (39%), Gaps = 47/324 (14%)
Query: 1515 LEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVDR-----LVPNYFKVSFY 1569
LE + VYK AY + L+ H ++NIY + + + + Y++V FY
Sbjct: 818 LELVIPVYKS-RKAYGQ-------LAKCHTLLTNIYESILDQESNPIPFIDATYYRVGFY 869
Query: 1570 GYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGSKLVNSFTEADKLLVSPPNGKFIH 1629
G F K L K +V+ + + +L +Y S +++ +L P+ + +
Sbjct: 870 GEKFGK-LDRKEYVYREPRDVRLGDIMEKLSHIY------ESRMDSNHILHIIPDSRQVK 922
Query: 1630 VISVEPR---LQISDEYATSDKKNDNNKVRLYVENRDLKTFSSSRRVAGTHGITDLWVIE 1686
++ LQI+ V +E+ DL SRR I L
Sbjct: 923 AEDLQAGVCYLQIT-------------AVDAVMEDEDL----GSRR----ERIFSLSTGS 961
Query: 1687 YIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQELSGLEDMCYKLMKENGDC 1746
T+ +FP L+NR V K SP+ NAI ++ + + L + + +GD
Sbjct: 962 VRARTEGSFPALVNRLLVTKSESLEFSPVENAIGMIETRT---TALRNELEEPRSSDGDH 1018
Query: 1747 SEVFSELSRNITGTIDAPINGGIAEYRVFYTDEETKSKLDPADVELLVAAFNELTIVLNR 1806
L R + G++ +N G+ + E ++L +++ L+AA E V R
Sbjct: 1019 LPRLQSLQRILQGSVAVQVNSGVLSVCTAFLSGEPATRLRSQELQQLIAALLEFMAVCKR 1078
Query: 1807 CLALHGQLCPISLSKSHTLLKDLF 1830
+ +H +L + HT L + F
Sbjct: 1079 AIRVHFRLIGEEDQEFHTQLVNGF 1102
>Hs22046914 [T] KOG1997 PH domain-containing protein
Length = 1573
Score = 54.7 bits (130), Expect = 1e-06
Identities = 72/299 (24%), Positives = 125/299 (41%), Gaps = 37/299 (12%)
Query: 1501 LYKEAARNFTKGLKLEKALTVYKDLADAYDKINYDLDGLSYVHGQISNIYTDLQNVD--R 1558
L ++AA F+ G E VYK L + + + L+ H ++ + + N D R
Sbjct: 1205 LLEQAAELFSTGGLYETVNEVYK-LVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKR 1263
Query: 1559 LVPNYFKVSFYGYGFPKNLRGKTFVFEGLPFEHITSVHNRLLKLYPGS------KLVNSF 1612
+ YF+V F+G F +L + FV++ + + +RL Y +++
Sbjct: 1264 MFGTYFRVGFFGSKFG-DLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDS 1322
Query: 1613 TEADKLLVSPPNGKFIHVISVEPRLQISDEYATSDK-----KNDNNKVRLYVENRDLKTF 1667
T DK + P N +I + VEP DEY D+ KN N + +Y F
Sbjct: 1323 TPVDKTKLDP-NKAYIQITFVEPYF---DEYEMKDRVTYFEKNFNLRRFMYTT-----PF 1373
Query: 1668 SSSRRVAGTHGITDLWVIEYIFETKSTFPTLMNRSEVVKVTEKRLSPINNAIKSLQQKIQ 1727
+ R G + + + + T FP + R V++ E L+PI AI+ +++K
Sbjct: 1374 TLEGRPRGE--LHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTL 1431
Query: 1728 ELSGLEDMCYKLMKENGDCSEVFSELSRNITGTIDAPINGGIAEY-RVFYTDEETKSKL 1785
+L+ + +E D L + G++ A +N G E +VF + KL
Sbjct: 1432 QLA------VAINQEPPDA----KMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKL 1480
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.320 0.136 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 109,519,715
Number of Sequences: 60738
Number of extensions: 4686781
Number of successful extensions: 12286
Number of sequences better than 1.0e-05: 12
Number of HSP's better than 0.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 12232
Number of HSP's gapped (non-prelim): 23
length of query: 1940
length of database: 30,389,216
effective HSP length: 121
effective length of query: 1819
effective length of database: 23,039,918
effective search space: 41909610842
effective search space used: 41909610842
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)