ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0761 good F KOG2902 Nucleotide transport and metabolism Dihydroorotase
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0761 248710 247619 -364
(364 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YLR420w [F] KOG2902 Dihydroorotase 543 e-154
SPAC16.03c [F] KOG2902 Dihydroorotase 315 5e-86
At4g22930 [F] KOG2902 Dihydroorotase 174 2e-43
>YLR420w [F] KOG2902 Dihydroorotase
Length = 364
Score = 543 bits (1398), Expect = e-154
Identities = 252/359 (70%), Positives = 307/359 (85%), Gaps = 1/359 (0%)
Query: 7 EYDLGITCDMHVHLRDGEMCKLITPTVKEGGISVAYVMPNLSPPVITLERVQEYKCTLES 66
E DLG+TCDMHVH+R+G MC+L+TP +++GG+S+AY+MPNL PP+ TL+RV EYK TL+
Sbjct: 4 EIDLGLTCDMHVHVREGAMCELVTPKIRDGGVSIAYIMPNLQPPITTLDRVIEYKKTLQK 63
Query: 67 LAPETTFLMSFYLCKDLTPELIHAAAKVGAIQGVKCYPAGVTTNSAQGVDPNDFTVFYPL 126
LAP+TTFLMSFYL KDLTP+LIH AA+ AI+GVKCYPAGVTTNSA GVDPNDF+ FYP+
Sbjct: 64 LAPKTTFLMSFYLSKDLTPDLIHEAAQQHAIRGVKCYPAGVTTNSAAGVDPNDFSAFYPI 123
Query: 127 FKAMEEEGIVLNLHGEKPSVA-GEKEDIHVLNAEESFLPALKKLHLDFPKLKIILEHCTT 185
FKAM+EE +VLNLHGEKPSV G+KE IHVLNAEE+FLPALKKLH DFP LKIILEHCT+
Sbjct: 124 FKAMQEENLVLNLHGEKPSVHDGDKEPIHVLNAEEAFLPALKKLHNDFPNLKIILEHCTS 183
Query: 186 AAAIKTIEEINADVKDPLDVMVAATITAHHLFLTIDDWAGNPINFCKPVAKLPSDKRALV 245
+AIKTIE+IN +VK DV VAAT+TAHHLFLTIDDWAGNP+NFCKPVAKLP+DK+ALV
Sbjct: 184 ESAIKTIEDINKNVKKATDVKVAATLTAHHLFLTIDDWAGNPVNFCKPVAKLPNDKKALV 243
Query: 246 QAATSGKPYFFFGSDSAPHPIENKAKHVGVCAGVFSQSLAIPYLAEIFETQGKLDTLKNF 305
+AA SGKPYFFFGSDSAPHP++NKA + GVCAGV+SQS AIPY+A++FE Q L+ LK F
Sbjct: 244 KAAVSGKPYFFFGSDSAPHPVQNKANYEGVCAGVYSQSFAIPYIAQVFEEQNALENLKGF 303
Query: 306 VSDAPLSFYALKPEDIKSNQNVTVFKKTTNIPEIITDGKGLRVAPFKAGDELHWAVRWD 364
VSD +SFY +K ++ S+ +FKK IP++I+DGK + + PFKAGD+L W+VRW+
Sbjct: 304 VSDFGISFYEVKDSEVASSDKAILFKKEQVIPQVISDGKDISIIPFKAGDKLSWSVRWE 362
>SPAC16.03c [F] KOG2902 Dihydroorotase
Length = 337
Score = 315 bits (808), Expect = 5e-86
Identities = 171/350 (48%), Positives = 220/350 (62%), Gaps = 22/350 (6%)
Query: 15 DMHVHLRDGEMCKLITPTVKEGGISVAYVMPNLSPPVITLERVQEYKCTLESLAPETTFL 74
DMHVHLR M K + PTV EGG+SVAYVMPNL PP+ T++ +YK +E L +TT+L
Sbjct: 10 DMHVHLRQDNMLKAVVPTVAEGGVSVAYVMPNLIPPITTVDACLQYKKEIEQLDSKTTYL 69
Query: 75 MSFYLCKDLTPELIHAAAKVGAIQGVKCYPAGVTTNSAQGVDPNDFTVFYPLFKAMEEEG 134
MS YL + TPE+I+ AAK G I+GVK YP G TTNS GV+ + FYP F AM+E G
Sbjct: 70 MSLYLSPETTPEVIYEAAKKG-IRGVKSYPKGATTNSESGVE--SYEPFYPTFAAMQETG 126
Query: 135 IVLNLHGEKPSVAGEKEDIHVLNAEESFLPALKKLHLDFPKLKIILEHCTTAAAIKTIEE 194
++LN+HGE P +D V AE FLP L LH FPKLKI+LEHCTTA A++ ++
Sbjct: 127 MILNIHGEVP----PSKDNTVFTAEPKFLPTLLDLHQRFPKLKIVLEHCTTADAVEAVKA 182
Query: 195 INADVKDPLDVMVAATITAHHLFLTIDDWAGNPINFCKPVAKLPSDKRALVQAATSGKPY 254
VA TITAHHL+LT DW +P FCKPVAK D+RAL++AATS P
Sbjct: 183 CGES--------VAGTITAHHLYLTQKDWQDDPYCFCKPVAKTERDRRALIEAATSKNPK 234
Query: 255 FFFGSDSAPHPIENKAKHVGVCAGVFSQSLAIPYLAEIFETQGKLDTLKNFVSDAPLSFY 314
FFFGSDSAPHP +K K AGVF+Q A YLAE+F+ +G+LD LK+F FY
Sbjct: 235 FFFGSDSAPHPRSSKLK-TPPAAGVFTQPFAASYLAEVFDKEGRLDALKDFACIFGRKFY 293
Query: 315 ALKPEDIKSNQNVTVFKKTTNIPEIITDGKGLRVAPFKAGDELHWAVRWD 364
+ P D K + N+ + K++ +PE + + + PF + L W W+
Sbjct: 294 CI-PLDFKES-NIVLKKESFRVPESVAND----LVPFHPNEVLQWHCSWE 337
>At4g22930 [F] KOG2902 Dihydroorotase
Length = 377
Score = 174 bits (440), Expect = 2e-43
Identities = 117/351 (33%), Positives = 175/351 (49%), Gaps = 25/351 (7%)
Query: 15 DMHVHLRDGEMCKLITPTVKEGGISVAYVMPNLSPPVITLERVQEY-KCTLESLAPETTF 73
D H+HLRDG++ + P A VMPNL PPV + Y K +++L E++F
Sbjct: 42 DWHLHLRDGDLLHAVVPH-SASNFKRAIVMPNLKPPVTSTAAAIIYRKFIMKALPSESSF 100
Query: 74 --LMSFYLCKDLTPELIHAAAKVGAIQGVKCYPAGVTTNSAQGVDPNDFTVFYPLFKAME 131
LM+ YL PE I A + G + VK YPAG TTNS GV + F P+ + M
Sbjct: 101 DPLMTLYLTDKTLPEEIRLARESGVVYAVKLYPAGATTNSQDGVT-DLFGKCLPVLEEMV 159
Query: 132 EEGIVLNLHGEKPSVAGEKEDIHVLNAEESFLPALKKLHLDFPKLKIILEHCTTAAAIKT 191
++ + L +HGE + + D + E P +++L P+LK+++EH TT A+
Sbjct: 160 KQNMPLLVHGEVTDPSIDVFDREKIFIETVLQPLIQRL----PQLKVVMEHITTMDAVNF 215
Query: 192 IEEINADVKDPLDVMVAATITAHHLFLT---IDDWAGNPINFCKPVAKLPSDKRALVQAA 248
+E + V AT+T HL L + P N+C PV K + A+V+A
Sbjct: 216 VESCK-------EGSVGATVTPQHLLLNRNALFQGGLQPHNYCLPVLKREIHREAIVKAV 268
Query: 249 TSGKPYFFFGSDSAPHPIENKAKHVGVCAGVFSQSLAIPYLAEIFETQGKLDTLKNFVSD 308
TSG FF G+DSAPH K G CAG++S +A+ A++F+ G LD L+ F S
Sbjct: 269 TSGSKKFFLGTDSAPHERSRKESSCG-CAGIYSAPIALSLYAKVFDEAGALDKLEAFTSF 327
Query: 309 APLSFYALKPEDIKSNQNVTVFKKTTNIPEIITDGKGLRVAPFKAGDELHW 359
FY L +++ +T+ K +P++ G + P AG+ L W
Sbjct: 328 NGPDFYGLP----RNSSKITLKKSPWKVPDVFNFPFG-EIVPMFAGETLQW 373
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.318 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,497,498
Number of Sequences: 60738
Number of extensions: 982939
Number of successful extensions: 2139
Number of sequences better than 1.0e-05: 3
Number of HSP's better than 0.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2126
Number of HSP's gapped (non-prelim): 3
length of query: 364
length of database: 30,389,216
effective HSP length: 108
effective length of query: 256
effective length of database: 23,829,512
effective search space: 6100355072
effective search space used: 6100355072
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)