ORF STATUS Function Best COG Functional category Pathways and functional systems
r_klactIV0773 good G KOG2533 Carbohydrate transport and metabolism Permease of the major facilitator superfamily
Only best alignment is shown:
BLASTP 2.2.3 [May-13-2002]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= r_klactIV0773 252052 253701 550
(550 letters)
Database: KOG eukaryal database 04/03
60,738 sequences; 30,389,216 total letters
Searching..................................................done
Color Key for Alignment Scores: 
Score E
Sequences producing significant alignments: (bits) Value
YJR152w [G] KOG2533 Permease of the major facilitator superfamily 641 0.0
SPCC417.10 [G] KOG2533 Permease of the major facilitator superfa... 416 e-116
SPBC1773.15 [G] KOG2533 Permease of the major facilitator superf... 387 e-107
SPCC757.13 [G] KOG2533 Permease of the major facilitator superfa... 251 2e-66
YLR004c [G] KOG2533 Permease of the major facilitator superfamily 229 1e-59
SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator super... 191 3e-48
SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator super... 174 3e-43
YLL055w [G] KOG2533 Permease of the major facilitator superfamily 162 9e-40
YGR260w [G] KOG2533 Permease of the major facilitator superfamily 136 9e-32
SPAC11D3.18c [G] KOG2533 Permease of the major facilitator super... 131 3e-30
SPBC1683.12 [G] KOG2533 Permease of the major facilitator superf... 130 4e-30
SPAC1002.16c [G] KOG2533 Permease of the major facilitator super... 130 7e-30
SPAC1039.04 [G] KOG2533 Permease of the major facilitator superf... 124 3e-28
YAL067c [G] KOG2533 Permease of the major facilitator superfamily 96 1e-19
YIL166c [G] KOG2533 Permease of the major facilitator superfamily 93 1e-18
SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superf... 90 8e-18
YCR028c [G] KOG2533 Permease of the major facilitator superfamily 79 2e-14
SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superf... 62 2e-09
YGR065c [G] KOG2533 Permease of the major facilitator superfamily 52 2e-06
>YJR152w [G] KOG2533 Permease of the major facilitator superfamily
Length = 543
Score = 641 bits (1653), Expect = 0.0
Identities = 313/516 (60%), Positives = 402/516 (77%), Gaps = 1/516 (0%)
Query: 36 NEIADRDALITTILSPDGKEVKITGDVDDAMKLALKSQNVVLTPEKDAKLLRKIDLMLFP 95
NE + +++T+LSP+GK V I+ VD+AMKLA +++ + +TPE+D KL KID +FP
Sbjct: 28 NEDVTAEPVLSTVLSPNGKIVYISDKVDEAMKLAEEAKEIEVTPEEDRKLRWKIDYCMFP 87
Query: 96 IMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGYLG-GLFILPFLMQK 154
+MCI+Y+VQFMDKI+TS+AA+MGL+TDLKMHG+QYS+V SAFYFGYL L + F+ Q+
Sbjct: 88 LMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQR 147
Query: 155 TKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESAITPAFTIITSQYWKK 214
T KML IVIWGM+LALHAAP+V YPSFI LR LLG ES +TP FTIIT+QYWK
Sbjct: 148 TSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKT 207
Query: 215 EEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKLVFIITGCITIVVGFIMMI 274
EEQF+R++ WFG NGLGSI AIAYG+YIH+DSY + W+ +F+ITG ITI +G ++ +
Sbjct: 208 EEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVITGVITIFIGILIFL 267
Query: 275 HLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQIVEAFKDVRTWLYFLFSVSS 334
+PD P KA F S+ EKL++V+RIR NQQGFGNH IKKYQI+EA KDVRTWLYFLF+VSS
Sbjct: 268 WIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIKKYQIIEALKDVRTWLYFLFTVSS 327
Query: 335 NIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVELVGCPLFGMLSFWCLKRKYKVVG 394
NIPNGGI++F SILL DF +S+ ++LL+ + +GAVELVGCPLFG+L+ + +K
Sbjct: 328 NIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFGILAVYAANKKIPFWK 387
Query: 395 SRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFGISPVSFICVLSCISSNTLGFTK 454
+L+WA FA + + CML FA + K ARLAG L+ ISPVSFICVLS IS+N+ G++K
Sbjct: 388 YKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYISPVSFICVLSNISANSSGYSK 447
Query: 455 KWTVSSINLLAYASANIAGPHTFIATQAPSYTGAKISLVVNYAAAMVIIVLIYIVNAREN 514
KWTVSSINL+AYA+AN+AGP TFIA QAP Y GAK+++VV YA +V++ ++ IVN REN
Sbjct: 448 KWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKVAMVVCYAVMIVLLSILLIVNLREN 507
Query: 515 KRRDKIEAERTHEQVVENIEFADLTDFENLKFRYAI 550
KRRDKI AER + EN+EF+DLTDFEN FRY +
Sbjct: 508 KRRDKIAAERGFPEETENLEFSDLTDFENPNFRYTL 543
>SPCC417.10 [G] KOG2533 Permease of the major facilitator superfamily
Length = 508
Score = 416 bits (1070), Expect = e-116
Identities = 234/527 (44%), Positives = 319/527 (60%), Gaps = 25/527 (4%)
Query: 24 DEKIQAVVSITANEIADRDALITTILSPDGKEVKITGDVDDAMKLALKSQNVVLTPEKDA 83
DEK++ S+ EI D D LSP G VD A AL + PE +
Sbjct: 7 DEKLKDPESVQNKEILDVDV---GDLSPKG--------VDAAFNYALDVDYDEIDPETER 55
Query: 84 KLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGYLG 143
+L+RKID +FP+MC++Y +QF+DK + S A IMGL+ DLKM G+ YS+ G+AFY GYL
Sbjct: 56 RLVRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLV 115
Query: 144 GLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESAITPA 203
F L+Q+ K L +VIWG +L + + NYP FI LR LLG +ESA +P
Sbjct: 116 FEFPASLLLQRFP-LSKTLCVFLVIWGFLLCMTSV--ANYPGFIALRVLLGMMESAASPG 172
Query: 204 FTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKLVFIITGC 263
F ++T+Q++K+ EQ R + W FNGLG I G +AYGL + S P+ WKL+FII G
Sbjct: 173 FILLTAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGL-AKRTSLPMRGWKLIFIICGV 231
Query: 264 ITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQIVEAFKDVR 323
+ I +GF+++ +PD+P KAWF +EE++ L+V+R+R N+QG GN+H K YQ E D+R
Sbjct: 232 LAIFLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETMLDIR 291
Query: 324 TWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVELVGCPLFGMLSF 383
TW+ F+ SV NIPNGGI FSS+L+K + T ++LL+ + +GA E G FG LS
Sbjct: 292 TWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSL 351
Query: 384 WCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFGISPVSFICVLS 443
+ + R+ A T I +G C+L+FA + A+LAG L +SP + I + +
Sbjct: 352 F--------IHKRMVLATITTCIALIGSCLLSFAGPPR-AQLAGYYLLMVSPGAMIVMFA 402
Query: 444 CISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQAPSYTGAKISLVVNYAAAMVII 503
ISSN G+TKK TV I L+ Y N+ GP TF A AP Y AK ++V YAA +V
Sbjct: 403 IISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTF 462
Query: 504 VLIYIVNARENKRRDKIEAERTHEQVVENIEFADLTDFENLKFRYAI 550
+Y VN RENKRRD++ AE E N EF DLTDFENL FRY +
Sbjct: 463 PALYYVNWRENKRRDQLAAEGKIEH-RPNAEFEDLTDFENLDFRYTL 508
>SPBC1773.15 [G] KOG2533 Permease of the major facilitator superfamily
Length = 497
Score = 387 bits (994), Expect = e-107
Identities = 207/492 (42%), Positives = 316/492 (64%), Gaps = 16/492 (3%)
Query: 61 DVDDAMKLALKSQNVVLTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQ 120
D + + + ++ ++ + KL K DL + P++C+I + Q+MDK T++ ++IMG++
Sbjct: 20 DSQEDVAVIFAEKHPIIDKSLNRKLKLKTDLWVMPLLCLISAFQYMDKSTSNYSSIMGIR 79
Query: 121 TDLKMHGEQYSYVGSAFYFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPS 180
TDL M G QY++VG++FY G++ L L+QK K+ ++ IV WG+++ L
Sbjct: 80 TDLNMVGNQYNWVGTSFYLGFMVFSLPLSTLLQKFP-LSKVTSAFIVAWGILMTLTCLVH 138
Query: 181 VNYPSFIFLRCLLGFLESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAY 240
+Y S+I R LLG LES ITPAF + +Q+++KEEQF R+ +NGLG + GG+++Y
Sbjct: 139 -SYASYIATRTLLGILESVITPAFVLFIAQWYRKEEQFFRMAFLVAWNGLGGLIGGSMSY 197
Query: 241 GLYIHK--DSYPLAAWKLVFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERI 298
GLY + ++ ++ W+++FIITG ITI+ G + IH+PD P KAWF SE+EK L+++R+
Sbjct: 198 GLYKRELENNLTMSPWRILFIITGLITIINGVFIFIHIPDEPSKAWFLSEKEKDLVLKRL 257
Query: 299 RENQQGFGNHHIKKYQIVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTD 358
+ G G+ KKYQI+EA +DVR +LYF ++ IPNGG++NFSSI+LK + +
Sbjct: 258 DTDHAGLGSKKFKKYQILEACRDVRMYLYFFLQIAVAIPNGGLSNFSSIMLK-NLGYVKG 316
Query: 359 KSLLVNMGSGAVELVGCPLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAK 418
K+LL+NM + ++ LFG++ + R+ A AI ++AFAK
Sbjct: 317 KALLMNMPTSSISFAALTLFGLIP--------EFTNRRMDIALVGLAINLTSGSLIAFAK 368
Query: 419 HDKSARLAGLMLFGISPVSFICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHTFI 478
A+LAG LFGISP+ +IC+LSCISSN+ G TKK +S+++++ Y N+ GP TF
Sbjct: 369 -PTHAQLAGYWLFGISPIPYICILSCISSNSAGHTKKVFMSAVSMIGYCVGNMVGPQTFR 427
Query: 479 ATQAPSYTGAKISLVVNYAAAMVIIVLIYIVNARENKRRDKIEAERTHEQVVENIEFADL 538
+TQAP Y GAK+S VV Y A+ II+ IY VN REN+RRD+ ++E E+ + DL
Sbjct: 428 STQAPKYQGAKVSFVVCYCVAIFIIIAIYAVNVRENRRRDEKNEYLSNELSEEDKK--DL 485
Query: 539 TDFENLKFRYAI 550
TDFEN +FRY+I
Sbjct: 486 TDFENPEFRYSI 497
>SPCC757.13 [G] KOG2533 Permease of the major facilitator superfamily
Length = 522
Score = 251 bits (641), Expect = 2e-66
Identities = 166/493 (33%), Positives = 263/493 (52%), Gaps = 20/493 (4%)
Query: 60 GDVDDAMKLALKSQNVVLTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGL 119
G D + L + T ++ ++L KIDL++ P+MCI Y +Q++DK S AA+ G+
Sbjct: 44 GTADAVAQELLADDDFTYTAKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGM 103
Query: 120 QTDLKMHGEQYSYVGSAFYFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAP 179
+TD + G YS + + FY GYL + LMQK + + ++ +W ++ L AA
Sbjct: 104 KTDTHIDGHTYSSMTTLFYAGYLVAQYPAAILMQKCRLSYFIFCNVF-LWSAMVCLMAA- 161
Query: 180 SVNYPSFIFLRCLLGFLESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIA 239
N PS + LR L G E++ITPAF IT+ ++++EEQ R CW+ FNG+ I G ++
Sbjct: 162 CRNGPSLLGLRFLAGIFEASITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILS 221
Query: 240 YGL-YIHKDSYPLAAWKLVFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERI 298
YGL +IH +A+W+ VFI+ G +++ G ++ + +P +P KA F S EK + +ER+
Sbjct: 222 YGLGHIHG---KVASWRYVFIVIGLMSLGWG-VVFVFIPSNPSKARFLSSREKRIALERV 277
Query: 299 RENQQGFGNHHIKKYQIVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTD 358
R+N+ G N K EAF D + + LF+ I N GI FS++++K ++
Sbjct: 278 RDNRTGLENKQFKWKHAYEAFLDPQVIMITLFTGVCMITN-GIGVFSTLIIK-GLGYNEL 335
Query: 359 KSLLVNMGSGAVELVGCPLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAK 418
S ++NM GA+E+ + G+L C K RL F + G C++ +
Sbjct: 336 HSAVLNMPLGAIEVAAMFISGVL---CKVFK----NGRLLIGVFMNCLTLAG-CLMIWKI 387
Query: 419 HDKS--ARLAGLMLFGISPVSFICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHT 476
D + RL G+ P S +LS ISSN G+TKK S+ + Y+ NI P
Sbjct: 388 PDSNPYGRLVGVWFTMWVPASSALLLSLISSNVAGYTKKTVTSATVFVFYSVGNIVSPQL 447
Query: 477 FIATQAPSYTGAKISLVVNYAAAMVIIVLIYIVNARENKRRDKIEAE-RTHEQVVENIEF 535
F + Q P Y +++V+ + I ++ ENKRRD++ AE + + ++N EF
Sbjct: 448 FKSGQTPEYIEGIQAMIVSLCIIIAIAFVLTGYYIYENKRRDRLLAEDPSLGESIKNEEF 507
Query: 536 ADLTDFENLKFRY 548
DLTD + KFRY
Sbjct: 508 MDLTDRQQPKFRY 520
>YLR004c [G] KOG2533 Permease of the major facilitator superfamily
Length = 523
Score = 229 bits (583), Expect = 1e-59
Identities = 163/523 (31%), Positives = 260/523 (49%), Gaps = 29/523 (5%)
Query: 31 VSITANEIADRDALITTILSPDGKEVKITGDVDDAMKLALKSQNVVLTPEKDAKLLRKID 90
VS ++ + D D + L +G + T + DD + A + N + E K+LRK+D
Sbjct: 23 VSTSSINVDDADVALR-FLKQNGLDESSTANEDDVV--AGEEANFYGSHELSPKVLRKVD 79
Query: 91 LMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGYLGGLFILPF 150
L + P +C Y + F+DK + AA MG++ LK G ++S +G+ F Y+ ++ +
Sbjct: 80 LFILPFLCCTYLLMFLDKALLNYAASMGIKDHLK--GNEFSNLGTIFSAAYIFMEPVVTY 137
Query: 151 LMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESAITPAFTIITSQ 210
L+QK K+L + I +WG+VLA HAA Y S + +R LLG ES+ I+
Sbjct: 138 LIQKFP-ISKILGTFITVWGIVLACHAACKT-YASLMVVRTLLGLFESSSAVGCIAISGM 195
Query: 211 YWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKLVFIITGCITIVVGF 270
Y+ K EQ +RI W G G I GG I++G ++H +W+++F++ G +T+ G
Sbjct: 196 YYTKSEQSARIGFWATQAGTGYIVGGLISFG-FLHYHGTAFTSWQIMFLVVGLVTVAFGV 254
Query: 271 IMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQIVEAF-KDVRTWLYFL 329
+ ++LPD+ AWF ++EEK+ +VE IR NQ G KK Q+ E F D TW L
Sbjct: 255 LTFLYLPDNVTNAWFLNKEEKIQVVEHIRANQTGLETKKFKKQQVKELFLHDKFTWPMLL 314
Query: 330 FSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVELVGCPLFGMLSFWCLKRK 389
+ S I G I F S+ + F F ++ L+ + GA+ + +++ L R
Sbjct: 315 LTACSQISTGAIGTF-SVTITGTFGFDKYETALLQLPIGAI----TAMIILITTQMLSRW 369
Query: 390 YKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFGISPVSFICVLSCI---- 445
+ + A C + +++ K L L L S CV++ I
Sbjct: 370 GHITLITTSMYIPAIIGC---IVLISLPLSHKIGNLFSLYLL----YSGSCVITNIYIWN 422
Query: 446 SSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQAPSYTGAKISLVVNYAAAMVIIVL 505
S NT G+TK+ ++I ++ Y + I P F A AP Y AKI+L+V + + +
Sbjct: 423 SCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAKIALLVTQCVCVPLQLY 482
Query: 506 IYIVNARENKRRDKIEAERTHEQVVENIEFADLTDFENLKFRY 548
I + +EN++RDK Q + +F DLTD EN FRY
Sbjct: 483 IGYICKKENEKRDK----EQEGQERKKYQFLDLTDIENRNFRY 521
>SPCPB1C11.03 [G] KOG2533 Permease of the major facilitator superfamily
Length = 570
Score = 191 bits (484), Expect = 3e-48
Identities = 153/555 (27%), Positives = 257/555 (45%), Gaps = 47/555 (8%)
Query: 25 EKIQAVVSITANEIADRDALITTILSPDGKEVKITGDVDDAMKLALKSQNV-VLTPEKDA 83
EK + V T + D D I + GK++ +D+ ++ + LTP++++
Sbjct: 34 EKKENAVDTTIAKPFDSDEDIADVEKAGGKKIN-NSLIDETFAFMQDAKKLDPLTPKQES 92
Query: 84 KLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGYLG 143
KL K+ + L ++ + + F+ K T S + I+GL D+ + QY+ + + FY GY+
Sbjct: 93 KLKWKLYIYLLLMLGFLDMMLFIGKATLSYSTILGLFDDVHITSNQYNNLNTLFYVGYIV 152
Query: 144 GLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESAITPA 203
G F ++MQ T K + + W +++ LH + NY I LR LGF ES + PA
Sbjct: 153 GQFPGHYIMQ-TFPLGKFVGLVTFSWSVIVFLHCC-AYNYGGLIALRFFLGFTESCLLPA 210
Query: 204 FTIITSQYWKKEEQ-FSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKLVFIITG 262
++ +EQ F + W G I G IAYGL S +A WKL IITG
Sbjct: 211 MEATMGMFFTHQEQAFLQPVFWISCLSCG-IPAGFIAYGLEFVTKS--IAPWKLFMIITG 267
Query: 263 CITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQ-GFGNHHIKKYQIVEAFKD 321
IT + + + PD+P KA F ++EEKL ++R+R++ + G N KK+Q +EA KD
Sbjct: 268 GITFFLSIFLFFYYPDNPSKARFLTDEEKLYTIDRVRKSTRGGIENKIFKKHQFIEALKD 327
Query: 322 VRTWLY----FLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVELVGCPL 377
TWL+ F +S+N+ + L+ S S LV + V +
Sbjct: 328 PITWLFTFAAFTLMLSNNLA------YQQNLIFTSLNVSDLNSTLVGVALAGYNTVSA-I 380
Query: 378 FGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFGISPVS 437
+ + + + S F+ G+ +A ++ LA +++ ++
Sbjct: 381 IATFAMYLIPNQ-----SAYHAMFWMLPSITGGIAFVALPWSNRIGELATMIIASDFGIT 435
Query: 438 FICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQAPSYTGAKI-SLVVNY 496
+I L ++ + G+TKK T + ++ YA ANI P + + AP Y A I +VV +
Sbjct: 436 YIIALGWTTATSTGYTKKLTRGLMFMVGYAIANIISPQLWQSRDAPRYYPAWIVQIVVAW 495
Query: 497 AAAMVIIVLIYIVNARENKRRDKIEAERTHEQVVENIE---------------------F 535
+I ++ ++ AR NK+R +++ ++ E +E IE
Sbjct: 496 FVTPIIYLVARVILARRNKQRKELKDKKIAEGSLETIEKTYVDTVDEFGNPVKVLIDNSM 555
Query: 536 ADLTDFENLKFRYAI 550
DLTD ENL F Y +
Sbjct: 556 LDLTDMENLNFVYPL 570
>SPBPB10D8.01 [G] KOG2533 Permease of the major facilitator superfamily
Length = 552
Score = 174 bits (441), Expect = 3e-43
Identities = 139/497 (27%), Positives = 240/497 (47%), Gaps = 40/497 (8%)
Query: 77 LTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSA 136
LTP++D +L K+ + ++ I+ + ++DK T S ++I+GL D ++ QY+ + +
Sbjct: 73 LTPKQDKRLRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTL 132
Query: 137 FYFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFL 196
FY G++ G L+Q+ K + + +W +++ LH A + N+ + LR LG +
Sbjct: 133 FYVGFVIGQIPGHMLLQRF-PVSKFVAASTALWTIIIFLHCA-AYNFSGLMALRFFLGLV 190
Query: 197 ESAITPAFTIITSQYWKKEEQ-----FSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPL 251
ES++ P ++ EQ F I+C +G N I G IAYG+ K++ +
Sbjct: 191 ESSLLPTMEATIGMFFPHSEQALLQPFFYISC-YGCN----IPAGFIAYGVQYAKNT--I 243
Query: 252 AAWKLVFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERI-RENQQGFGNHHI 310
+ WKL II G IT + + + PD+ A F +++E+L V+R+ R N G +
Sbjct: 244 SPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTF 303
Query: 311 KKYQIVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAV 370
KKYQ++EA KD TWL F F V N + + + LL S S LV + S
Sbjct: 304 KKYQVIEALKDPVTWL-FTFHVFCNQLSNNLA-YQQNLLFTSLNVSDLNSTLVGVASAGY 361
Query: 371 ELVGCPLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLML 430
V + +K + G+ W + A G+ +A + K LA +++
Sbjct: 362 NCVSA-IIATYMMSVIKNQSAFHGA--IWYIPSIA---GGIACVAMSWDHKIGELAAIII 415
Query: 431 FGISPVSFICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQAPSYTGAKI 490
+ FI L +++ G+TKK T + ++ YA ANI GP + + AP Y A I
Sbjct: 416 ASNFGIPFIISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWI 475
Query: 491 -SLVVNYAAAMVIIVLIYIVNARENKRR------DKIEAERTHEQVVENI---------- 533
+V+ ++ + ++++I + R NK+R +K + E+T + +++
Sbjct: 476 VQIVIAWSVSPFVLLIIRWILVRRNKKRLALLEQNKEQYEKTWIETIDSSGNHVSGFYEN 535
Query: 534 EFADLTDFENLKFRYAI 550
DLTD ENL F Y +
Sbjct: 536 SMLDLTDQENLSFIYPL 552
>YLL055w [G] KOG2533 Permease of the major facilitator superfamily
Length = 531
Score = 162 bits (411), Expect = 9e-40
Identities = 141/502 (28%), Positives = 233/502 (46%), Gaps = 41/502 (8%)
Query: 77 LTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSA 136
+TPE++ KL RK+ L +F + I + +MDK T S +I+G D + Y+ V +
Sbjct: 43 ITPEQEKKLKRKLFLTIFTFVSAINLLLYMDKATLSYDSILGFFEDTGLTQNTYNTVNTL 102
Query: 137 FYFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFL 196
FY G+ G F +L QK K L ++ W +++ L + + N+ + LR LG
Sbjct: 103 FYVGFAIGQFPGQYLAQKL-PLGKFLGGLLATWTILIFL-SCTAYNFSGVVALRFFLGLT 160
Query: 197 ESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKL 256
ES + P ++ E+ + +F I G IAYG+ +H + ++ WK+
Sbjct: 161 ESVVIPILITTMGMFFDASERAAAQPFFFAACMGSPIPTGFIAYGV-LHITNPSISLWKI 219
Query: 257 VFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQ-QGFGNHHIKKYQI 315
II G +T ++ ++++ P++P FFS +E++ ++ R++ + KK Q
Sbjct: 220 FTIIIGGLTFIMTVVVILWFPNNPADVKFFSIQERVWIIRRVQASTGSSIEQKVFKKSQF 279
Query: 316 VEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVELVGC 375
EA KD TWL+ LF + + N + ++L + S LV++ +GA V C
Sbjct: 280 REAMKDYITWLFGLFFLLQQLAN-NLPYQQNLLFEGMGGVDALGSTLVSV-AGAGFAVVC 337
Query: 376 PLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFG-IS 434
L + K+K + S L F+ + A +K LA + + G I
Sbjct: 338 AFIATL----MLAKWKNI-SALTAIFWTLPALVGSIAAAALPWDNKIGILANICMAGQIF 392
Query: 435 PVSFICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQAPSYTGAKI-SLV 493
+ FI LS SS+ G+TKK T SS++L A ANI P + +P + A I +V
Sbjct: 393 GIPFIIALSWASSSASGYTKKLTRSSVSLFAMGIANIISPQIWREKDSPRFLPAWIVQIV 452
Query: 494 VNYAAAMVIIVLIYIVNARENKRRDK---------------IEAER----------THEQ 528
++++ A I++LI+ + R N +R K IE+E THE
Sbjct: 453 LSFSLAPAILLLIHFILKRRNNQRLKNYDENLQNYLDRIQLIESENPSSIEEGKVVTHE- 511
Query: 529 VVENIEFADLTDFENLKFRYAI 550
N+ DLTD EN F Y +
Sbjct: 512 --NNLAVFDLTDLENETFIYPL 531
>YGR260w [G] KOG2533 Permease of the major facilitator superfamily
Length = 534
Score = 136 bits (342), Expect = 9e-32
Identities = 120/476 (25%), Positives = 221/476 (46%), Gaps = 33/476 (6%)
Query: 82 DAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGY 141
+ ++LRK+D+ L P+M ++Y + +DK NA + GL D+ + G QY+ + F+ Y
Sbjct: 81 EKRVLRKMDIYLIPLMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATY 140
Query: 142 LGGLFILPFLMQKTKKFM--KMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESA 199
+ + + K M ++ SI + ++L A NY I +R LLG E
Sbjct: 141 V----LFDPIGTNLLKIMGPPLMMSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGM 196
Query: 200 ITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKLVFI 259
I PA + S +++E+ R F L S +GG IAYG K S L W+ ++I
Sbjct: 197 IYPAINMYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYG--CSKISGSLKDWQYIYI 254
Query: 260 ITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQIVEAF 319
+ GCI++ L + + +WFF++EEK + ER + + + +Q+ +A
Sbjct: 255 VEGCISLGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFEWFQVWQAV 314
Query: 320 KDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVELVGCPLFG 379
KDV+TW + ++ G+T F I++ F+ ++ L+ + + + +F
Sbjct: 315 KDVKTWASAVALFGIDLTTFGLTVFLPIII-TSMGFTNVRAQLMTV---PIYFLTAIVFF 370
Query: 380 MLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFGI------ 433
+ + W + K+ + A T+I G+ ++ +++ G+ FG+
Sbjct: 371 ICAVW--SDRIKLRSPFILGACLTTSI---GIAIVL------GSQVHGVRYFGVYILCMG 419
Query: 434 SPVSFICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQAPSY-TGAKISL 492
V+ C +S NT + K+ T INL + + + F+A P Y G ISL
Sbjct: 420 IYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISL 479
Query: 493 VVNYAAAMVIIVLIYIVNARENKRRDKIEAERTHEQVVENIEFADLTDFENLKFRY 548
+ + +V I++ REN ++ I +R +E + E I + + +N +F+Y
Sbjct: 480 AFQVFSIFMTVVQIFLYK-RENDKKKAI-IDRCNE-LGEPIPYDERLSDKNPEFKY 532
>SPAC11D3.18c [G] KOG2533 Permease of the major facilitator superfamily
Length = 498
Score = 131 bits (329), Expect = 3e-30
Identities = 114/490 (23%), Positives = 220/490 (44%), Gaps = 37/490 (7%)
Query: 40 DRDALITTILSPDGKEVKITGDVDDAMKLALKSQNVVLTPEKDAKLLRKIDLMLFPIMCI 99
D ++ + ++ + + + DVD +LK + P+ + KLL K+DL++ PI+
Sbjct: 13 DEHSIYASEINKEKLQNTASPDVDYGDTASLK-----IDPKVEKKLLLKMDLVISPIIGF 67
Query: 100 IYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGYLGGLFILP-FLMQKTKKF 158
+Y + F+D+ NAA+ G+ L ++GE+ + S FY Y+ L P ++ K K
Sbjct: 68 LYLMAFLDRSNIGNAAVAGMTEALSLYGERLNVAVSIFYVLYI--LVETPSVVLVKRIKA 125
Query: 159 MKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESAITPAFTIITSQYWKKEEQF 218
+ML I W M + S +Y I R +LG LE + PA + + ++ ++EQ
Sbjct: 126 SRMLAFISFAWSMTVLFSGFMS-SYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQC 184
Query: 219 SRITCWFGFNGLGSIWGGAIAYGL-YIHKDSYPLAAWKLVFIITGCITIVVGFIMMIHLP 277
R++ F GL +GG AY L +H + W+ ++I+ G ++ + + + LP
Sbjct: 185 QRLSYLFASAGLAGAFGGLFAYALEQVHAGN--KEGWQWIYIVEGLVSFIGVPLCLFALP 242
Query: 278 DSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQIVEAFKDVRTWLYFLFSVSSNIP 337
D + AWF + EE+ + + R N + G H + ++ +AFKD + ++ +++
Sbjct: 243 DKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRKAFKDPKVYVSATSQFCADMV 302
Query: 338 NGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVEL----VGCPLF--GMLSFWCLKRKYK 391
G ++F +++K G G V L + P++ G++SF +
Sbjct: 303 LYGFSSFLPVIIK---------------GLGFVGLQTNYMTIPVYIAGVISFLFVAWLSD 347
Query: 392 VVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLFGIS-PVSFICVLSCISSNTL 450
R + A+ + +G ++ A +A+ + I + L +++N
Sbjct: 348 RTQLRAVYLISASTVVAVGY-IIMLASDSNAAKYTATYIIAIGCYIGPGLNLGWLNNNVA 406
Query: 451 GFTKKWTVSSINLLAYASANIAGPHTFIATQAPSY-TGAKISLVVNYAAAMVIIVLIYIV 509
G K+ T I S+ I + + AP Y G +L + +V+ + +
Sbjct: 407 GHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTLGCVIVGGLAYVVMFFSL 466
Query: 510 NARENKRRDK 519
NK+RD+
Sbjct: 467 R-YVNKKRDE 475
>SPBC1683.12 [G] KOG2533 Permease of the major facilitator superfamily
Length = 482
Score = 130 bits (328), Expect = 4e-30
Identities = 82/284 (28%), Positives = 143/284 (49%), Gaps = 2/284 (0%)
Query: 74 NVVLTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYV 133
++ + +++AKL+RK+D L P+ ++Y + F+D+ NAA++GL+ DLK+ QYS
Sbjct: 25 DITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAA 84
Query: 134 GSAFYFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLL 193
S FY Y+ L++K L+++I+ W +V + +Y S + R LL
Sbjct: 85 VSVFYATYITAETPSVLLVKKFGPHY-YLSAMIIGWSLV-TIFTCFVRHYWSLVLTRLLL 142
Query: 194 GFLESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAA 253
G E P ++ S +K+EEQ R+ + + +GG IA GL S L
Sbjct: 143 GICEGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPN 202
Query: 254 WKLVFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKY 313
W ++II G I+ + ++ LPD P A F + EK L+ R + Q+ G+ +
Sbjct: 203 WGWLYIIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWT 262
Query: 314 QIVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFST 357
Q +AFKD + ++ + ++ GI+ F +LK + +S+
Sbjct: 263 QFRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSS 306
>SPAC1002.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 499
Score = 130 bits (326), Expect = 7e-30
Identities = 113/457 (24%), Positives = 203/457 (43%), Gaps = 19/457 (4%)
Query: 73 QNVVLTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSY 132
+N LT + LL ++DL+L P + I+Y V F+D+ NA + GL DLK+ G+Q++
Sbjct: 39 ENTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKGDQFNI 98
Query: 133 VGSAFYFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCL 192
+ S FY ++ LF +P + K K + + IVI + + N+ + R +
Sbjct: 99 IASVFYVTFI--LFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGGLLAARLV 156
Query: 193 LGFLESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSY-PL 251
LGF E+ + P + + + + E RI F + L +GG AY + +H D
Sbjct: 157 LGFCEAGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGLFAYAV-LHMDGVGGF 215
Query: 252 AAWKLVFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIK 311
A W+ +FII G I V G + +P+ KAWF S+ + ++ +R E H
Sbjct: 216 AGWRWLFIIEGLIGFVCGVAVYFIIPNDITKAWFLSKTHQEMMRKRQLERAADLEAAHFD 275
Query: 312 KYQIVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMGSGAVE 371
+ AF D + +LY L + G + F ++ SL V + V
Sbjct: 276 WKGVKSAFTDFKVYLYALSEFGQDTCLYGFSTFLPAIISG----MGYTSLSVQYMTIPVY 331
Query: 372 LVGCPLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLF 431
++G + SF L ++ G L +G +L +++KS L
Sbjct: 332 ILGAATYIAASF--LSDRFHHRGIIL---IIGNIFPIVGYILLLACQNNKSVLYFACYLC 386
Query: 432 GISPVSFICV-LSCISSNTLGFTKKWTVSSINL-LAYASANIAGPHTFIATQAPSY-TGA 488
+ + + ++ +S+N K+ T S+ L +A +S +AG I P Y G
Sbjct: 387 SVGVYTGAGLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQ---IYRYPPKYIAGH 443
Query: 489 KISLVVNYAAAMVIIVLIYIVNARENKRRDKIEAERT 525
SL+ + + ++ +V I+ + + +K++ + + T
Sbjct: 444 LTSLIAIFISTVLHVVNIFFLKHQNSKKQKSLASSST 480
>SPAC1039.04 [G] KOG2533 Permease of the major facilitator superfamily
Length = 507
Score = 124 bits (312), Expect = 3e-28
Identities = 109/456 (23%), Positives = 208/456 (44%), Gaps = 29/456 (6%)
Query: 76 VLTPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGS 135
+L + + +L RK D + P++ ++Y +DK SNA G+ DL G+QY+ + S
Sbjct: 44 ILDHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMIS 103
Query: 136 AFYFGYLGGLFILPF-LMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLG 194
FY ++ L PF + K ++L ++ +G ++L A N+ + +R LG
Sbjct: 104 IFYIPFV--LCAFPFSYLYKRFGAARILPFFMLSFG-AMSLCQAAVKNFGGMMAVRWFLG 160
Query: 195 FLESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAW 254
ESA+ P + ++++ E R+ ++ + S +GG +AYG++ H L W
Sbjct: 161 MAESAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVF-HIKGGKLQGW 219
Query: 255 KLVFIITGCITIVVGFIMMIHLPDSPDKAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQ 314
+ +F+I G +T + ++ + LP S + A F ++EEK L RI + + + Q
Sbjct: 220 QYLFLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQ 279
Query: 315 IVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMG---SGAVE 371
+ FK L+ L ++ +P I N+ ++ FS+ + L+ + SGA+
Sbjct: 280 SLTVFKHPIAILWLLEEMALGVPLNSINNWLPQIVAA-MGFSSVNTNLMTVAPAISGAIW 338
Query: 372 LVGCPLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLAGLMLF 431
L+ +F +S + R G L A T I F+ + H + A ++
Sbjct: 339 LL---VFAFISDFLKNR-----GIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMT 390
Query: 432 GISPVSFICVLSCISSNTLGFTKKWTVSSI-----NLLAYASANIAGPHTFIATQAPSYT 486
+ S + + ++NT +++ +S+ N++ SANI P AP Y
Sbjct: 391 AGAAASSVLTSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQ-----DAPKYV 445
Query: 487 GAKISLVVNYAAAMVIIVL-IYIVNARENKRRDKIE 521
A + + + +++V I + +N+RRD +
Sbjct: 446 PA-LGITAGFGGLGILLVASISVYMFFDNRRRDNAQ 480
>YAL067c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 96.3 bits (238), Expect = 1e-19
Identities = 103/458 (22%), Positives = 200/458 (43%), Gaps = 33/458 (7%)
Query: 78 TPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAF 137
T K+ KLL K+D++L CI Y V+++D + +NA + G++ DL G + +
Sbjct: 124 TSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMY 183
Query: 138 YFGYLGGLFILPFLMQKTKKFMK-MLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFL 196
G + +F LPFL+ K + +L S+ + W + L + AA + P +R +G
Sbjct: 184 TVGNI--IFQLPFLIYLNKLPLNYVLPSLDLCWSL-LTVGAAYVNSVPHLKAIRFFIGAF 240
Query: 197 ESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSY-PLAAWK 255
E+ A+ + ++K +E R ++ +G + G I +Y + L W+
Sbjct: 241 EAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWR 300
Query: 256 LVFIITGCITIVVGFIMMIHLPDSPDKAW--FFSEEEKLLLVERIRENQQGFGNHHIKKY 313
FII +++VVG I LP P + F +++E L +R++ENQ G + K +
Sbjct: 301 WNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVF 360
Query: 314 QI---VEAFKDVRTWLYFLFSV----SSNIPNGGITNFSSILLKEDFQFSTDKSLLVNMG 366
I F D + ++ L+++ SN+ +G + LK ++S K ++M
Sbjct: 361 DIKLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYL----LWLKSLKRYSIPKLNQLSMI 416
Query: 367 SGAVELVGCPLFGMLSFWCLKRKYKVVGSRLAWAFFATAICFMGVCMLAFAKHDKSARLA 426
+ + +V L G+++ R + ++ F +G +LA + A+
Sbjct: 417 TPGLGMVYLMLTGIIADKLHSRWFAII--------FTQVFNIIGNSILAAWDVAEGAKWF 468
Query: 427 GLML----FGISPVSFICVLSCISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQA 482
ML + ++PV + + T+ T+ ++N++A +S + +A
Sbjct: 469 AFMLQCFGWAMAPVLYSWQNDICRRDAQ--TRAITLVTMNIMAQSSTAWISVLVWKTEEA 526
Query: 483 PSY-TGAKISLVVNYAAAMVIIVLIYIVNARENKRRDK 519
P Y G + + ++ V++Y E K
Sbjct: 527 PRYLKGFTFTACSAFCLSIWTFVVLYFYKRDERNNAKK 564
>YIL166c [G] KOG2533 Permease of the major facilitator superfamily
Length = 542
Score = 92.8 bits (229), Expect = 1e-18
Identities = 116/485 (23%), Positives = 210/485 (42%), Gaps = 33/485 (6%)
Query: 78 TPEKDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAF 137
T +++ KL+RK+DL +F + I+++ + + + A DLKM+ Y+ +G
Sbjct: 66 TKDEEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYN-LGQTV 124
Query: 138 YFGYLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLE 197
Y + L+ K +++ IV+W V+ + A N FI RCLLG ++
Sbjct: 125 YLVIFLASELPGNLLSKRFGPERVIPVQIVLWS-VICITQAGLKNRGQFIATRCLLGMVQ 183
Query: 198 SAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAWKLV 257
P + S Y+ E R++ ++ L I G +A G+ + + LA W+ +
Sbjct: 184 GGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYL 243
Query: 258 FIITGCITIVVG---FIMMIHLPDSPDKAWF------FSEEEKLLLVERIRENQQGFGN- 307
FII G +++ VG F +M P ++ F F+E E+ ++V RI + G+
Sbjct: 244 FIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDM 303
Query: 308 ---HHIKKYQIVEAFKDVRTWLYFLFSVSSNIPNGGITNFSSILLKEDFQFSTDKSLLVN 364
+ +I+ + W F+ +++ I + ++ S++LK +ST S ++
Sbjct: 304 SNRQPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILK-SLNYSTFLSNILA 362
Query: 365 MGSGAVELVGCPLFGMLSFWCLKRKYKVVGSRLAWAF-FATAICFMGVCMLAFAKHDKSA 423
+ A+ L+ PL +LS LK K VG W F ++ + + K+
Sbjct: 363 IPGQALLLINLPLAALLS-RKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLT 421
Query: 424 RLAGLMLFGISPVSFICVLS-CISSNTLGFTKKWTVSSINLLAYASANIAGPHTFIATQA 482
+ GL ++ +S + S T+G + N+ A A IA + +
Sbjct: 422 GILGLPYTHSILAGWVSEISNSVRSRTVG------TALYNMSAQVGAIIAS-NMYRNDDK 474
Query: 483 PSYT-GAKISL-VVNYAAAMVIIVLIYIVNARENKRRDKIEAERTHEQVVENIEFADLTD 540
P YT G KI L + M + Y ++ NK +D+ T E E I + D T
Sbjct: 475 PYYTRGNKILLGFTCFNICMAVATKFYYIS--RNKYKDRKWNSMTKE---EQINYLDTTK 529
Query: 541 FENLK 545
+ +K
Sbjct: 530 DKGMK 534
>SPBC2G2.01c [G] KOG2533 Permease of the major facilitator superfamily
Length = 514
Score = 90.1 bits (222), Expect = 8e-18
Identities = 72/250 (28%), Positives = 124/250 (48%), Gaps = 17/250 (6%)
Query: 82 DAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGY 141
+ KLL KID + C+ Y + ++D+ + +NA + G+Q DLKMHG + + F GY
Sbjct: 21 EQKLLIKIDWFILSYCCVSYFINYLDRSSINNAYLSGMQEDLKMHGNELQDINVVFTCGY 80
Query: 142 LGGLFILPFLMQKTKKFMKMLTSIIVIWG-MVLALHAAPSVNYPSFIFLRCLLGFLESAI 200
+ G + +Q+ + + + ++WG M + A SV + + LR + E A
Sbjct: 81 IIGQLPGSYALQRVPARL-WFSVMNILWGLMTIFSFAVHSVR--ALMILRFFMAVAE-AS 136
Query: 201 TPAFTIITSQYWKKEEQFSRITCWFGFNGL-GSIWGGAIAYGLYIHKDSY-PLAAWKLVF 258
T A T W KE + + F +GL G+++ G + ++ + L+ W+ +F
Sbjct: 137 TFAGTHYILGAWYKESELCKRAGIFSASGLVGTMFAGYLQTAVHSSLNGKGGLSGWRWLF 196
Query: 259 IITGCITIVVGFIMMIHLPDSPD--KAWFFSEEEKLLLVERIRENQQGFGNHHIKKYQIV 316
II G +TI + + PD P+ KA +F+E+EK L +R+ + KK +
Sbjct: 197 IIDGILTIPLSLYGLFLFPDVPETTKAPYFTEQEKELSFKRLPARPK-------KKPLTL 249
Query: 317 EAFKD-VRTW 325
+A KD VR+W
Sbjct: 250 KAIKDIVRSW 259
>YCR028c [G] KOG2533 Permease of the major facilitator superfamily
Length = 512
Score = 78.6 bits (192), Expect = 2e-14
Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 3/203 (1%)
Query: 81 KDAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFG 140
K LL KIDL + +C+ Y + ++D++ +NA I G++ DLKM G + + F G
Sbjct: 25 KKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIG 84
Query: 141 YLGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVNYPSFIFLRCLLGFLESAI 200
Y+ G+ + LM L+ WG+ L L ++ +R ES
Sbjct: 85 YIVGM-VPNNLMLLCVPPRIWLSFCTFAWGL-LTLGMYKVTSFKHICAIRFFQALFESCT 142
Query: 201 TPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDS-YPLAAWKLVFI 259
+ ++K++E R + G +GS++ G + ++ H + LA W+ +FI
Sbjct: 143 FSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFI 202
Query: 260 ITGCITIVVGFIMMIHLPDSPDK 282
I CIT+ + I P PD+
Sbjct: 203 IDFCITLPIAIYGFIFFPGLPDQ 225
>SPAC1B3.16c [G] KOG2533 Permease of the major facilitator superfamily
Length = 568
Score = 62.0 bits (149), Expect = 2e-09
Identities = 106/485 (21%), Positives = 196/485 (39%), Gaps = 77/485 (15%)
Query: 28 QAVVSITANEIADRDALITTILSPDGKEVKITGDVDDAMKLALKSQNVVLTPEKDAKLLR 87
+ V S++ ++ + ++ TT++ D ++ + +D + +K Q + + + LR
Sbjct: 24 EIVESVSDSKPSLKNQFSTTVI--DSSDLNV---FNDGAETTVKEQEFTSSELRRLQKLR 78
Query: 88 -KIDLMLFPIMCIIYSVQFMDKITTSNAAIMG-------LQTDLKMHGEQYSYVGSA-FY 138
K+DL + P + I+Y + + T S + M +QT L + Y +G A FY
Sbjct: 79 LKMDLRIIPCLWILYFLSCCLRFTVSLSFTMNTAQGHSLIQT-LSGYSAHYLALGLALFY 137
Query: 139 FGYLGGLFILPF-LMQKTKKFMKMLTSIIVIWGMVLALHAAPSV---NYPSFIFLRCLLG 194
GY+ +F +P LM + ++ I + G+V A HA N S++ LR LG
Sbjct: 138 VGYI--IFEVPSNLMMAFIEPRIWVSRIQLTIGVVGACHAVLGTKHGNAQSYVALRFFLG 195
Query: 195 FLESAITPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDSYPLAAW 254
ES + P S++++ + RI ++ + + ++ G + L +
Sbjct: 196 VAESGLWPGLAYYMSRWYRGKHLGKRIGWYYTAAQIAAAAVSLVSAGFQKMDGARGLYGY 255
Query: 255 KLVFIITGCITIVVGFIMMIHLPD-----------------------SPDKAWFFSEEEK 291
+ +F+I G + I + LP SP + F + +K
Sbjct: 256 QWMFLIWGVVAIAQALSIPWWLPAVASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADK 315
Query: 292 LLLVERIRENQQGFGNHHIKKYQIVEAFK---DVRTWLYFLFSVSSNIPNGGITNFSSIL 348
L I E G K++Q + K D+R W + L GI N+ +++
Sbjct: 316 SLHSRYIAEMNVG------KRWQWSDLLKSCLDLRVWPFILMYFGIVGVGNGIFNYCTLI 369
Query: 349 LKE-DFQFSTDKSLLVNMGSGAVELVG----CPLFGMLSFWCLKRKYKVVGSRLAWAFFA 403
++E + FS L+N + +G PL+ +K+ F
Sbjct: 370 IEEINPSFSGIDISLLNAPIWLADALGIVTVMPLYDR-----FHKKFS----------FF 414
Query: 404 TAICFMGVCMLAFAKHDKSA--RLAGLML--FGISPVSFICVLSCISSNTLGFTKKWTVS 459
T C + + LA A + A R GL++ FG+ P IC+ C +S + S
Sbjct: 415 TGSCLIIIAGLAVANYAPRAWSRYGGLLMIGFGLGPTVPICMAWCSASMAKTYGDVGVAS 474
Query: 460 SINLL 464
S+ L+
Sbjct: 475 SLALV 479
>YGR065c [G] KOG2533 Permease of the major facilitator superfamily
Length = 593
Score = 52.0 bits (123), Expect = 2e-06
Identities = 53/229 (23%), Positives = 99/229 (43%), Gaps = 14/229 (6%)
Query: 82 DAKLLRKIDLMLFPIMCIIYSVQFMDKITTSNAAIMGLQTDLKMHGEQYSYVGSAFYFGY 141
+ +LL K+D+++ ++ + +D +NA + ++ DL M G Y Y + G
Sbjct: 118 ERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGA 177
Query: 142 LGGLFILPFLMQKTKKFMKMLTSIIVIWGMVLALHAAPSVN-YPSFIFLRCLLGFLESAI 200
+ +F LPF M +F + ++ G A N R +L +A
Sbjct: 178 I--VFQLPF-MYLLPRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAY 234
Query: 201 TPAFTIITSQYWKKEEQFSRITCWFGFNGLGSIWGGAIAYGLYIHKDS-YPLAAWKLVFI 259
P I ++ +E SR+ +F LGS+ G + ++ + + LA W+ +F+
Sbjct: 235 YPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFL 294
Query: 260 ITGCI----TIVVGFIMMIHLPDSPDKAW--FFSEEEKLLLVERIRENQ 302
I T ++GF + +P P K + F ++EE + R + NQ
Sbjct: 295 IDAIAISLPTAIIGFFV---IPGVPSKCYSLFLTDEEIRIARARNKRNQ 340
Database: KOG eukaryal database 04/03
Posted date: Apr 14, 2003 1:07 PM
Number of letters in database: 30,389,216
Number of sequences in database: 60,738
Lambda K H
0.326 0.139 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,280,727
Number of Sequences: 60738
Number of extensions: 1253390
Number of successful extensions: 3878
Number of sequences better than 1.0e-05: 19
Number of HSP's better than 0.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3810
Number of HSP's gapped (non-prelim): 19
length of query: 550
length of database: 30,389,216
effective HSP length: 111
effective length of query: 439
effective length of database: 23,647,298
effective search space: 10381163822
effective search space used: 10381163822
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)